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         Akinetic Mutism:     more detail
  1. Preserved auditory cognitive ERPs in severe akinetic mutism: a case report [An article from: Cognitive Brain Research] by L. Naccache, M. Obadia, et all 2004-04-01

41. Brain Maps
56. akinetic mutism is a neurobehavioral condition that results whenthe dopaminergic pathways in the brain are damaged. Damage
http://www.biausa.org/Pages/brain maps.html

42. Alphabetical Topic Index (AZ) Jump To A B C D E F G H I J K L M
Embolism, Air. Back To Top ^ Ak Akathisia, DrugInduced Akathisia,Drug-Induced akinetic mutism akinetic mutism. Back To Top ^ Al
http://www.uscuh.com/apps/Intermap/topiclist/SectionA.html
Alphabetical Topic Index (A-Z):
Jump To: A B C D ... Ax
A
Ab
Abdominal Cancer Seeding

Neoplasm Seeding

Abdominal Problems
Colorectal Cancer Overview

Early Stage Colorectal Cancer

Stage I Colorectal Cancer

Liver Cirrhosis
...
Stage II or III Colorectal Cancer

Abducens Nerve Injury Abducens Nerve Injury Abetalipoproteinemia Abetalipoproteinemia Abnormal Menstrual Bleeding Abnormal Menstrual Bleeding Abnormal Pap/Dysplasia Abnormal PAP Smear Cervical Dysplasia Abortion, Incomplete Abortion, Incomplete Abortion, Missed Abortion, Missed Abortion, Septic Abortion, Septic Abortion, Threatened Abortion, Threatened Abuse - Physical or Mental Rape Shaken Baby Syndrome Back To Top ^ Ac Acanthamoeba Keratitis Acanthamoeba Keratitis Acantholysis Acantholysis Acanthosis Nigricans Acanthosis Nigricans Acatalasia Acatalasia Accelerated Idioventricular Rhythm Accelerated Idioventricular Rhythm Accessory Nerve Diseases Accessory Nerve Diseases Achlorhydria Achlorhydria Achondroplasia Achondroplasia Acinetobacter Infections Acinetobacter Infections Acne Acne Overview And Treatment Acne Keloid Acne Keloid Acoustic Neuroma Neuroma, Acoustic

43. Publications
J Neurol 1986, 2334447. Németh Gy, Hegedüs K, Molnár L akinetic mutism andlocked-in syndrome the functional-anatomical basis for their differentiation.
http://www.neuropat.dote.hu/refer.html
Representative Publications

44. Untitled
72, 8788 (1985). Németh, Gy., Hegedüs, K., Molnár, L. akinetic mutism andlocked-in syndrome The functional-anatomical basis for their differentation.
http://www.neuropat.dote.hu/explab/lmolnar.htm
Curriculum vitae Name: Date and place of birth: Education:
  • 1941 - Graduated from High School June 1947 - M.D. ('sub laurea almae matris'), Medical School, University of Szeged, Hungary 1965 - Ph.D. in Physiology, University of Paris, Sorbonne, France 1966 - Ph.D. in Neurology, Hungarian Academy of Sciences 1977 - Doctor of Medical Sciences (D.Sci), Hungarian Academy of Sciences
Board Certification: Neurology, Neurosurgery, Psychiatry Brief chronology of employment:
  • 1959-1960 Visiting Scientist, Institute of Physiology, Cologne, Germany 1969 (Jan-April) Scientific Representative of the UNESCO, State University of Pernambuco, Recife, Brasil 1969-1992 Head, Department of Neurology and Psychiatry, University of Debrecen, Hungary
  • Societies:
    • International Brain Research Organization (IBRO) Member of "Kuratorium der Donau-Symposien für Neurologische Wissenschaften" "Founder member" of the International Society for Cerebral Blood Flow and Metabolism Honorary President of the Hungarian EEG and Clinical Ekectrophysiological Society Member der Deutschen Akademie der Naturforscher Leopoldina, Halle, Germany

    45. Fleshandbones Bookshop
    Extrapyramidal system; Dystonia; Cerebellar function; Sensation; The unconsciouspatient Lockedin syndrome; Coma vigil (akinetic mutism); Chronic vegetative
    http://www.fleshandbones.com/bookshop/title.cfm?ISBN=0750625201

    46. EMedicine - HIV-1 Encephalopathy And AIDS Dementia Complex
    prominent. Later, severe psychomotor retardation and language impairmentbecome obvious, leading to akinetic mutism. Neurological
    http://www.emedicine.com/NEURO/topic447.htm

    47. SYMPTOMS OF PSYCHIATRIC SYMPTOMS
    unconsciousness. 6. Coma vigil coma in which the patient appears tobe asleep but ready to be aroused (also known as akinetic mutism). 7
    http://utmed.com/wmanuel/psyc/symptoms.html
    SYMPTOMS OF PSYCHIATRIC SYMPTOMS
    I. Consciousness : State of awareness A. Disturbances of Consciousness Disorientation: disturbance of orientation in time, place, or person Clouding of consciousness: incomplete clear-mindedness with disturbances in perception and attitudes Stupor: lack of reaction to and unawareness of surroundings, the patient is akinetic, a state of unresponsiveness with immobility and mutism Delirium: clouded of consciousness, bewildered, confused, disoriented reaction associated with fear and hallucinations Coma: profound degree of unconsciousness Coma vigil: coma in which the patient appears to be asleep but ready to be aroused (also known as akinetic mutism) Twilight state: a transitory disturbance of consciousness with hallucinations Dreamlike state: often used as a synonym for complex partial seizure or psychomotor epilepsy Somnolence: abnormal drowsiness
    II. Emotion : a complex feeling state with psychic, somatic, and behavioral components that is related to affect and mood A.

    48. Meaning Of Akinetic Mutism
    Search For Lycos Zone Home, Family Zone, Teachers Zone, Click hereto see more, Back to Fact Monster Home Page Home World. US People
    http://infoplease.kids.lycos.com/ipd/A0311365.html
    Search For: Lycos Zone Home Family Zone Teachers Zone
    Dictionary

    Pathol., Psychiatry.
    a state of apparent alertness with normal eye movements but no speech or other voluntary motion, usually due to a stroke.
    akinete
    Akins
    Awards and Press
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    49. ªL¥úÅï Âå®v
    1995;14537541. 2. KL Lin, HS Wang, ML Chou, TN Rui Role of Cavum Septum Pellucidumin akinetic mutism. of Hydrocephalic Children. Pediatric Neurology.
    http://www.cgmh.com.tw/chldhos/intr/c4a90/new_page_9.htm
    ¸g¾ú ¬ã¨s½×¤å ­Ó¤H­º­¶ ¸g¾ú 1. Resident, July, 1991 - July, 1994, Department of Pediatrics, Chang Gung Memorial Hospital 2. Chief Resident, July, 1994 - June, 1995, Department of Pediatrics, Chang Gung Children Hospital 3. Attending, since July, 1995, Department of Pediatrics, Chang Gung Children Hospital 4. Research fellow, July 2000 to August 2001, Laboratory for Brain Magnetic Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston Chief, Division of Pediatric Neurology, Department of Pediatrics, Chang Gung Children Hospital , since October 1, 1999 ¦a¾_¥tþ¨a¥Á V.S. ¯«¸g¥Ö½§¯g­Ô¸s ¨­°ª¶i«×¸¨«á ÅéÀ˧ä¥X­ì¦] Åöíw¦W¤H¿ý «¢¦ò±d«Â¹Ï®ÑÀ]ªº¦a¤U«Ç ¦­¦w
    ¤U³· ...
    ¬ì¾Ç»P´¼¼z ¬ã¨s½×¤å Publications : KL Lin
    , HS Wang, TN Rui: Sonographic Diagnosis of an Infant with a Corpus Callosum Lipoma with Extracranial Extension. Journal of Ultrasound in Medicine. 1995;14:537-541 KL Lin , HS Wang, ML Chou, TN Rui: Role of Cavum Septum Pellucidum in Akinetic Mutism of Hydrocephalic Children. Pediatric Neurology. 1997;16:156-159

    50. Listings Of The World Health Conditions And Diseases
    Listings World Health Conditions and Diseases Neurological DisordersBrain Diseases akinetic mutism. Listings World,
    http://listingsworld.com/Health/Conditions_and_Diseases/Neurological_Disorders/B

    51. Regis Et Al. 11-96
    The morbidity (new deficit or deterioration of a preexisting deficit) was, inour study, separated into severe (coma, akinetic mutism, or other longterm
    http://www.c3.hu/~mavideg/ns/Regis11-96.html
    CLINICAL STUDIES
    Pineal Region Tumors and the Role of Stereotactic Biopsy: Review of the Mortality, Morbidity, and Diagnostic Rates in 370 Cases
    OBJECTIVE: It is classically considered that the morbidity and mortality rates are greater for stereotactic biopsies of pineal region tumors, compared with tumors in other regions. However, to date, the number of cases studied in the literature has been insufficient to evaluate these parameters and compare them with the morbidity and mortality rates for stereotactic biopsies of tumors located elsewhere. METHODS: With the aim of evaluating these parameters, we reviewed 370 stereotactic biopsies of pineal region tumors, from 15 French neurosurgical centers. We statistically verified the absence of heterogeneity of the different French centers with regard to diagnostic, mortality, and morbidity rates. In contrast, statistical heterogeneity was clearly seen for the large stereotactic biopsy series (for all tumor locations) in the literature. RESULTS: The mortality rate was 1.3% (5 patients of 370), and 3 patients suffered severe neurological complications. This study is the first to clearly demonstrate that the mortality, morbidity, and diagnostic rates for stereotactic biopsies are not different in the pineal region. CONCLUSION: Our conclusion is that stereotactic biopsy must remain a main diagnostic modality for tumors of the pineal region.

    52. Efficacy Of Bilateral Pallidotomy
    permanent. No complications resulted from his first procedure; however,he experienced akinetic mutism following the second. In
    http://www.c3.hu/~mavideg/jns/2-3-8.html
    Efficacy of bilateral pallidotomy
    Richard Kim, M.D., M.S., Ron Alterman, M.D., Patrick J. Kelly, M.D., Enrico Fazzini, D.O., Ph.D, David Eidelberg, M.D., Ph.D., Alaksandar Beric, M.D., D.Sci., and Djorje Sterio, M.D. New York University Center for the Study and Treatment of Movement Disorders, New York, New York; Department of Neurosurgery, New York University Medical Center, New York, New York; and North Shore University Hospital, Manhassett, New York The authors completed 11 of 12 attempted bilateral pallidotomies among 150 patients undergoing pallidotomy at New York University. In all but one patient, the pallidotomies were separated by at least 9 months. Patients were selected for bilateral pallidotomy if they exhibited bilateral rigidity, bradykinesia, or levodopa-induced dyskinesia prior to treatment or if they exhibited disease progression contralateral to their previously treated side. The Unified Parkinson's Disease Rating Scale (UPDRS) and timed upper-extremity tasks of the Core Assessment Protocol for Intracerebral Transplantation (CAPIT) were administered to all 12 patients in the "off" state (12 hours without receiving medications) preoperatively and again at 6 and 12 months after each procedure. The median UPDRS and contralateral CAPIT scores improved 60% following the initial procedure (p = 0.008, Wilcoxon rank sums test). The second pallidotomy generated only an additional 10% improvement in the UPDRS and CAPIT scores ipsilateral to the original procedure (p = 0.05). Worsened speech was observed in two cases. In the 12th case, total speech arrest was noted during test stimulation. Speech returned within minutes after stimulation was halted. Lesioning was not performed.

    53. Mental Health Foundation Homepage
    Agoraphobia. Agraphia. AIDS. Akathesia. Akathisia (2). Akinesia. akinetic mutism.Alcohol Abuse. Alexia. Alexithymia. Alexythymia (2). Alienation. Alternative Therapies.
    http://www.mentalhealth.org.uk/wordbank.cfm?wbletter=A

    54. Neurogate.com Neurosurgery Search Engine And Neurosurgery Custom Medline Searchi
    Afferent Neurons Afferent Pathways - Ageusia - Agnosia - Agraphia - AIDS DementiaComplex - akinetic mutism - Allergic Encephalomyelitis - Alzheimer Disease
    http://www.neurogate.com/neuro/index2.html
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    55. SpringerLink: Neuroradiology - Abstract Volume 37 Issue 7 (1995) Pp 531-534
    This patient followed an atypical clinical course 16 months had passed before shedeveloped akinetic mutism, and periodic sharp waves had not been detected on
    http://link.springer-ny.com/link/service/journals/00234/bibs/5037007/50370531.ht
    Neuroradiology
    ISSN: 0028-3940 (printed version)
    ISSN: 1432-1920 (electronic version) Table of Contents Abstract Volume 37 Issue 7 (1995) pp 531-534
    Serial MRI in early Creutzfeldt-Jacob disease with a point mutation of prion protein at codon 180
    S. Ishida (1), M. Sugino (1), N. Koizumi (2), K. Shinoda (1), N. Ohsawa (1), T. Ohta (3), T. Kitamoto (4), J. Tateishi (4)
    (1) First Department of Internal Medicine, Osaka Medical College, Daigaku-cho 2-7, Takatsuki City, Osaka 569, Japan
    (2) Division of Cardiology, Department of Internal Medicine, Minami Osaka General Hospital, Higashikagaya Suminoe-ku, 1-18-18 Osaka City 559, Japan
    (3) Department of Neurosurgery, Osaka Medical College, Daigaku-cho 2-7, Takatsuki City 569, Japan
    (4) Department of Neuropathology, Neurological Institute, Kyusyu University, Maidashi Higashi-ku 3-1-1, Hukuoka City 812, Japan
    Received: 14 April 1994 Accepted: 7 June 1994 Abstract We report a 66-year-old woman with histologically diagnosed Creutzfeldt-Jacob disease (CJD), followed with MRI from an early clinical stage. MRI demonstrated expansion of the high cortical signal on T2-weighted images, which differs from previous MRI reports of CJD. This patient followed an atypical clinical course: 16 months had passed before she developed akinetic mutism, and periodic sharp waves had not been detected on EEG after 2 years in spite of her akinetic mutism. Brain biopsy showed primary spongiform changes in the grey matter, and a point mutation of the prion protein gene at codon 180 was discovered using polymerase chain reaction direct sequencing and Tth 111 I cutting. This is the first case with the point mutation of the codon 180 variant with an atypical clinical course and characteristic MRI findings.

    56. Central And Extrapontine Myelinolysis Following Allogeneic Peripheral Haematopoi
    seizures, visual hallucinations and cortical blindness; also ocular flutter, 2 parkinsonism,3 cortical dysarthria or speech apraxia, 4 akinetic mutism 5 and
    http://www.nature.com/cgi-taf/DynaPage.taf?file=/bmt/journal/v31/n1/full/1703781

    57. BDJ | Login To The British Dental Journal
    and 65 years of age. 14 There is rapid progression, over weeks, to anakinetic mutism. Aside from the predominant mental deterioration
    http://www.nature.com/cgi-taf/DynaPage.taf?file=/bdj/journal/v188/n8/full/480050

    58. HONselect - Brain Diseases
    Hydrocephalus, Hypothalamic Diseases. Intracranial Hypertension, NeuroaxonalDystrophies. akinetic mutism, Amblyopia. Amnesia, Transient Global, Brain Death.
    http://www.hon.ch/HONselect/Selection/C10.228.140.html
    HONselect: Introduction Search Browse Favourites List of Rare Disease add HONselect Contents on "Brain Diseases": MeSH hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Wondering about the holiday blues! MeSH Hierarchy English French German Spanish Portuguese MeSH Broader term(s) Diseases
    Nervous System Diseases
    Central Nervous System Diseases
    Brain Diseases MeSH definition Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
    Subheadings : complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy
    MeSH Narrow term(s) Auditory Diseases, Central Basal Ganglia Diseases Brain Abscess Brain Damage, Chronic Brain Diseases, Metabolic Brain Injuries Brain Neoplasms Cerebellar Diseases Cerebrovascular Disorders Dementia Encephalitis Encephalomalacia Epilepsy Headache Disorders Hydrocephalus Hypothalamic Diseases Intracranial Hypertension Neuroaxonal Dystrophies Akinetic Mutism Amblyopia Amnesia, Transient Global

    59. Slider Index: AK, AKS, Kalashnikov - Akutagawa, Ryunosuke
    Akers,_Tom Akers, Brian Dana Akers, Tom AkhalTeke Associations Breeders Akhmatova,Anna Akihabara Denno Gumi Akiko Akin, David akinetic mutism Akins, Rhett
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    60. New York City Department Of Health & Mental Hygiene - Communicable Disease - 200
    of the following four clinical features Myoclonus; Visual or cerebellarsigns; Pyramidal/extrapyramidal signs; akinetic mutism and;
    http://www.nyc.gov/html/doh/html/cd/02md15.html
    ALERT #15: Surveillance for transmissible spongiform encephalopathies, including the classic and new variant forms of Creutzfeld-Jakob Disease July 2, 2002 Please distribute to colleagues in Neurology, Pathology, Internal Medicine, Infectious Diseases, Family Practice and Geriatrics Dear Colleagues in Infection Control, Infectious Diseases and Laboratory Medicine: The New York City Board of Health added transmissible spongiform encephalopathies (TSEs) to the reportable disease list in Section 11.03 of the New York City Health Code effective July 28, 2001 due to concerns about the potential for the introduction or emergence of new variant Creutzfeldt-Jakob disease (CJD) in the United States. TSEs, such as the classic and new variant forms of CJD and kuru, are prion-mediated diseases that cause progressive neurodegenerative disorders. These diseases have long incubation periods and cause characteristic spongiform changes in the brain tissue resulting in fatal dementing illnesses. Background:
    The classic form of CJD occurs sporadically (approximately 90% of cases), through iatrogenic transmission (

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