21. 1Up Health > Alport Syndrome > Causes, Incidence, And Risk Factors Of Alport Syn Comprehesive information on alport syndrome (Hematuria nephropathy - deafness,Hemorrhagic familial nephritis, Hereditary deafness and nephropathy http://www.1uphealth.com/health/alport_syndrome_info.html

1Up Health Alport syndrome Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Alport syndrome Information Alport syndrome Causes, Incidence, and Risk Factors Alternative names : Hematuria - nephropathy - deafness, Hemorrhagic familial nephritis, Hereditary deafness and nephropathy, Hereditary nephritis Definition : Alport syndrome is an inherited (usually X-linked) disorder involving damage to the kidney, blood in the urine , and in some families, loss of hearing . The disorder may also include eye defects Causes, Incidence, and Risk Factors Alport syndrome is very similar to hereditary nephritis. There may be nerve deafness and congenital eye abnormalities associated with Alport syndrome. The cause is a mutation in a gene for collagen. The disorder is uncommon, and most often affects males since the genetic defect is typically found on the X chromosome. In women, the disorder is usually mild, with minimal or no symptoms. Women can transmit the gene for the disorder to their children, even if the woman has no symptoms of the disorder. In men, the symptoms are more severe and progress faster. The disorder causes chronic glomerulonephritis with destruction of the glomeruli. Initially, there are no symptoms. Progressive destruction of the glomeruli causes

22. Alport Syndrome . alport syndrome affects about onein 5,000 Americans, striking men more often and severely than women....... alport syndrome. Definition. http://www.healthatoz.com/healthatoz/Atoz/ency/alport_syndrome.html

Encyclopedia Index A Home Encyclopedia Encyclopedia Index A Alport syndrome Definition A hereditary disease of the kidneys that primarily affects men, causing blood in the urine, hearing loss and eye problems. Eventually, kidney dialysis or transplant may be necessary. Description Alport syndrome affects about one in 5,000 Americans, striking men more often and severely than women. There are several varieties of the syndrome, some occurring in childhood and others not causing symptoms until men reach their 20s or 30s. All varieties of the syndrome are characterized by kidney disease that usually progresses to chronic kidney failure and by uremia (the presence of excessive amounts of urea and other waste products in the blood). Causes and symptoms Alport syndrome in most cases is caused by a defect in one or more genes located on the X chromosome. It is usually inherited from the mother, who is a normal carrier. However, in up to 20% of cases there is no family history of the disorder. In these cases, there appears to be a spontaneous genetic mutation causing Alport syndrome. Blood in the urine (hematuria) is a hallmark of Alport syndrome. Other symptoms that may appear in varying combinations include:

23. Member Sign In Assuming that he does have alport syndrome, I have 2 questions (1) Should he berelisted for transplantation and if so, what is the chance of a similar outcome http://www.medscape.com/viewarticle/414192

If you are having trouble logging in: In order to use Medscape, your browser must be set to accept "cookies." To find out how to adjust your browser settings, please click here Log In Username Password Forgot your password? Not a Member? Register Now for free access to: MEDLINE (Optimized for Physicians) 200+ Free CME Courses 25 Medical Specialty Sites 100+ Medical Journals Conference Coverage Daily Medical News About Medscape Help WebMD Health

24. NORD - National Organization For Rare Disorders, Inc. alport syndrome. View Cart/Checkout. Copyright 1988, 1989 Synonyms of AlportSyndrome Hereditary Nephritis; Nephritis and Nerve Deafness, Hereditary; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Alport Syndro

25. AskDocTrish.com -- Alport Syndrome alport syndrome. Enter your email to join A Newsletter From Doc Trish today! Returnto Table of Contents My father died of alport syndrome several years ago. http://www.askdoctrish.com/alport.html

var srl33t_id = '1455'; Alport Syndrome Enter your email to join "A Newsletter From Doc Trish" today! Home Ask Doc Trish See The Answers About Doc Trish ... Link To Us Be notified when this page changes it's private powered by ChangeDetection We subscribe to the HONcode principles of the Health On the Net Foundation Thank you for visiting! I am glad you are here. Don't forget to bookmark this page! Return to Table of Contents My father died of Alport Syndrome several years ago. I was told I would have no problems with the disease, but my sister is a carrier of it, and any male children she would have could be at risk. I've been able to find very little on the disease, and what I have found is pretty technical. What is the disease and how does it affect those who have it? If you look at a piece of the body's tissue from just about any area of the body under a microscope, you will see something called a basement membrane, which is sort of like "glue" that holds different body tissues together. In Alport syndrome, there is a genetic birth defect which causes a key ingredient to be missing in the basement membranes of the kidney, the ear and the eye. So the "glue" starts coming apart, so to speak. This leads to kidney failure, deafness, and eye problems at an early age (20-30 years old). For some reason, men have worse symptoms than women do.

26. Alport Syndrome (Alport Deafness-Nephropathy, [Deafness/Hearing Loss]-Nephritis HOME alport syndrome (Alport DeafnessNephropathy, Deafness/HearingLoss-Nephritis Syndrome, Dickinson Syndrome). http://www.bdid.com/alport.htm

HOME Alport Syndrome (Alport Deafness-Nephropathy, [Deafness/Hearing Loss]-Nephritis Syndrome, Dickinson Syndrome) Alport Syndrome Home Page ALPORT SYNDROME Le syndrome d'Alport Alport syndrome (AS, ATS) ... SINDROME DI ALPORT Autosomal Dominant ALPORT SYNDROME, AUTOSOMAL DOMINANT Autosomal Recessive ALPORT SYNDROME, AUTOSOMAL RECESSIVE X-Linked ALPORT SYNDROME, X-LINKED; ATS HOME

27. Birth Disorder Information Directory - A alport syndrome. alport syndrome (Alport DeafnessNephropathy, Deafness/HearingLoss-Nephritis Syndrome, Dickinson Syndrome) List http://www.bdid.com/defectag.htm

HOME Ag-Am Aganglionosis Total Intestinal Aganglionosis total intestinal AGANGLIONOSIS, TOTAL INTESTINAL Aganthia with Holoprosencephaly and Situs Inversus Aganthia holoprosencephaly situs inversus AGNATHIA-HOLOPROSENCEPHALY Agammaglobulinemia List of Sites Agenesis of the Cerebellar Vermis List of Sites Agenesis of the Corpus Callosum List of Sites Related Books Aglossia Adactylia (Oromandibular Limb Hypoplasia) Aglossia adactylia AGLOSSIA-ADACTYLIA Also see Hanhart Syndrome Agnathia -Holoprosencephaly See Holoprosencephaly-Agnathia Agyria-Pachygyria Type I See Miller-Dieker (Lissencephaly) Syndrome Aicardi Syndrome List of Sites Aicardi-Goutieres Syndrome (Encephalopathy-Basal Ganglia Calcification) Aicardi-Goutieres syndrome Encephalopathy, Familial Infantile, with Calcification of Basal Ganglia and Chronic Cerebrospinal Fluid Lymphocytosis Related Books Cutis verticis gyrata thyroid aplasia mental retardation ... CUTIS VERTICIS GYRATA, THYROID APLASIA, AND MENTAL RETARDATION Aksu Stockhausen Syndrome (Branchial Arch Defects) branchial arch defects Al-Awadi Farag Teebi Syndrome (Primary Hypogonadism with Partial Alopecia) Al awadi farag teebi syndrome HYPOGONADISM, PRIMARY, AND PARTIAL ALOPECIA

28. Alport Syndrome alport syndrome. (See HEARING IMPAIRMENTS, KIDNEY DISEASES, HEREDITARY, VISIONIMPAIRMENTS). alport syndromeHereditary Nephritis Study,. Dept. http://www.childhealthinfo.com/alport-syndrome.htm

ALPORT SYNDROME (See HEARING IMPAIRMENTS, KIDNEY DISEASES, HEREDITARY, VISION IMPAIRMENTS) Alport Syndrome-Hereditary Nephritis Study, Dept. of Physiology, Room #156 University of Utah 410 Chipea Way Salt Lake City, UT 84198-1297 [Home] [Printed Guide] [Child Care for the '90's] [Links] ... MoreInfo@ChildHealthInfo.com

29. Alport Syndrome Articles, Support Groups, And Resources alport syndrome articles, support groups, and resources for patientsfrom Med Help International (www.medhelp.org). alport syndrome. http://www.medhelp.org/HealthTopics/Alport_Syndrome.html

[Health Topics A-Z] A B C D ... Z Alport Syndrome Medical Glossary: ALPORT SYNDROME [Med Help Home] [Library Search] [Medical Forums] ... [Patient Network] Revised: 3/30/2003

30. ALPORT SYNDROME alport syndrome An inherited disorder (sex linked autosomal dominant)involving damage to the kidneys, hematuria, and hearing loss. http://www.medhelp.org/glossary2/new/GLS_0252.HTM

ALPORT SYNDROME - An inherited disorder (sex linked autosomal dominant ) involving damage to the kidneys hematuria , and hearing loss. In some individuals vision may also be affected. This genetic disease is uncommon affecting 2 out of 100,000 people. Symptoms include loss of hearing, abnormal color to urine, swelling, cough, and decline in vision. Med Help Home Search Ask the Doctor Patient Network The medical glossary has been made possible by a generous donation from:

31. ThirdAge - Adam - Alport Syndrome alport syndrome. Definition Alport Causes, incidence, and risk factorsalport syndrome is very similar to hereditary nephritis. There http://www.thirdage.com/health/adam/ency/article/000504.htm

document.write(''); document.write(''); document.write('<'); document.write('/SCRIPT>'); document.write(''); document.write(''); document.write('<'); document.write('/A>'); document.write('<'); document.write('/NOSCRIPT>'); document.write('<'); document.write('/IFRAME>'); Activities Computers Family Tree Health ... Prevention Alport syndrome Definition: Alport syndrome is an inherited (usually X-linked) disorder involving damage to the kidney, blood in the urine , and in some families, loss of hearing . The disorder may also include eye defects Alternative Names: Hereditary nephritis; Hematuria - nephropathy - deafness; Hemorrhagic familial nephritis; Hereditary deafness and nephropathy Causes, incidence, and risk factors: Alport syndrome is very similar to hereditary nephritis. There may be nerve deafness and congenital eye abnormalities associated with Alport syndrome. The cause is a mutation in a gene for collagen. The disorder is uncommon, and most often affects males since the genetic defect is typically found on the X chromosome. In women, the disorder is usually mild, with minimal or no symptoms. Women can transmit the gene for the disorder to their children, even if the woman has no symptoms of the disorder. In men, the symptoms are more severe and progress faster.

32. GeneReviews: Alport Syndrome Your browser does not support HTML frames so you must view alport syndromein a slightly less readable form. Please follow this link to do so. http://www.geneclinics.org/profiles/alport/

Your browser does not support HTML frames so you must view Alport Syndrome in a slightly less readable form. Please follow this link to do so.

33. Health Ency.: Disease: Alport Syndrome alport syndrome. The disorder may also include eye defects. Causes andRisks. alport syndrome is very similar to hereditary nephritis. http://www.accessatlanta.com/shared/health/adam/ency/article/000504.html

SEARCH: The Web Yellow Pages HOME AJC.COM Illustrated Health Encyclopedia Important notice Ency. home Disease A Alport syndrome Overview Symptoms Treatment Prevention Alternative names: Hereditary nephritis; Hematuria - nephropathy - deafness; Hemorrhagic familial nephritis; Hereditary deafness and nephropathy Definition: Alport syndrome is an inherited (usually X-linked) disorder involving damage to the kidney, blood in the urine , and in some families, loss of hearing . The disorder may also include eye defects Causes and Risks Alport syndrome is very similar to hereditary nephritis. There may be nerve deafness and congenital eye abnormalities associated with Alport syndrome. The cause is a mutation in a gene for collagen. The disorder is uncommon, and most often affects males since the genetic defect is typically found on the X chromosome. In women, the disorder is usually mild, with minimal or no symptoms. Women can transmit the gene for the disorder to their children, even if the woman has no symptoms of the disorder. In men, the symptoms are more severe and progress faster. The disorder causes chronic glomerulonephritis with destruction of the glomeruli. Initially, there are no symptoms. Progressive destruction of the glomeruli causes

34. Alport Syndrome . alport syndrome affects aboutone in 5,000 Americans, striking men more often and severely than women.......MAIN SEARCH INDEX alport syndrome. http://www.hendrickhealth.org/healthy/000053.htm

MAIN SEARCH INDEX Alport syndrome Definition Description Causes and symptoms Diagnosis ... Resources Definition A hereditary disease of the kidneys that primarily affects men, causing blood in the urine, hearing loss and eye problems. Eventually, kidney dialysis or transplant may be necessary. Description Alport syndrome affects about one in 5,000 Americans, striking men more often and severely than women. There are several varieties of the syndrome, some occurring in childhood and others not causing symptoms until men reach their 20s or 30s. All varieties of the syndrome are characterized by kidney disease that usually progresses to chronic kidney failure and by uremia (the presence of excessive amounts of urea and other waste products in the blood). Causes and symptoms Alport syndrome in most cases is caused by a defect in one or more genes located on the X chromosome. It is usually inherited from the mother, who is a normal carrier. However, in up to 20% of cases there is no family history of the disorder. In these cases, there appears to be a spontaneous genetic mutation causing Alport syndrome. Blood in the urine (hematuria) is a hallmark of Alport syndrome. Other symptoms that may appear in varying combinations include:

35. ALPORT SYNDROME: FROM GENES TO BEDSIDE Editorial. alport syndrome from genes to bedside. Mohammed Akhtar, MD, FCAP,FRCPA, FRCPath. alport syndrome clinical phenotypes, incidence and pathology. http://www.kfshrc.edu.sa/annals/191/98-290ED.html

Editorial Alport syndromE: from genes to bedside Mohammed Akhtar, MD, FCAP, FRCPA, FRCPath Alport syndrome (AS) is an inherited disorder characterized by the familial occurrence in successive generations of progressive nephritis with hematuria and of neural hearing loss. Ever since the early descriptions of this disease by Guthrie and Hurst, the pathogenetic basis of AS has remained an enigma. The first clues to an understanding of the pathogenesis of AS were provided by the advent of electron microscopy in the early 1970s, which helped to characterize the changes in glomerular basement membrane (GBM). Ultrastructural studies usually revealed variable thinning of the GBM in the early stages and regional thinning and thickening, frequently accompanied by splitting and lamellation, as the disease progresses (Figures 1 and 2). This in turn indicated that the genetic abnormality in AS was likely to be found in some gene or genes encoding proteins responsible for the structural integrity of GBM. In 1971, Kefalides demonstrated for the first time that GBM is composed of a unique type of collagen, which he referred to as type IV collagen. This inspired Spear to suggest that AS might be caused by mutation in type IV collagen gene.

36. ORPHANET® : Alport Syndrome With Macrothrombocytopenia ORPHANET. ORPHANET database access. alport syndrome with macrothrombocytopenia.Direct access to details Alias Epstein syndrome. Home Page. http://www.orpha.net/static/GB/alport_with_macrothrombocytopenia.html

ORPHANET database access Alport syndrome with macrothrombocytopenia Direct access to details Alias : Home Page

37. ORPHANET® : Alport Syndrome Translate this page ORPHANET. ORPHANET database access. alport syndrome.Direct access to details Alias Home Page. http://www.orpha.net/static/GB/alport.html

ORPHANET database access Alport syndrome Direct access to details Alias : Home Page

38. Alport Syndrome | BluePrint For Health You are here Home Health A to Z alport syndrome.alport syndrome. Turkington, Carol A. http://blueprint.bluecrossmn.com/topic/topic100586414

Search COMPLEMENTARY CARE Acupuncture Massage therapy Fitness centers ... SITE AWARDS You are here: Home Health A to Z Alport Syndrome Alport Syndrome Turkington, Carol A. Below: Definition Description Causes and symptoms Diagnosis ... Resources Definition A hereditary disease of the kidneys that primarily affects men, causing blood in the urine, hearing loss and eye problems. Eventually, kidney dialysis or transplant may be necessary. Description Alport syndrome affects about one in 5,000 Americans, striking men more often and severely than women. There are several varieties of the syndrome, some occurring in childhood and others not causing symptoms until men reach their 20s or 30s. All varieties of the syndrome are characterized by kidney disease that usually progresses to chronic kidney failure and by uremia (the presence of excessive amounts of urea and other waste products in the blood). Causes and symptoms Alport syndrome in most cases is caused by a defect in one or more genes located on the X chromosome. It is usually inherited from the mother, who is a normal carrier. However, in up to 20% of cases there is no family history of the disorder. In these cases, there appears to be a spontaneous genetic mutation causing Alport syndrome. Blood in the urine (hematuria) is a hallmark of Alport syndrome. Other symptoms that may appear in varying combinations include:

39. Alport Syndrome | AHealthyAdvantage You are here Home Health A to Z alport syndrome. alport syndrome. Turkington,Carol A. Blood in the urine (hematuria) is a hallmark of alport syndrome. http://www.ahealthyadvantage.com/topic/topic100586414

Site Search Ills and Conditions Women's Health Men's Health Senior Health ... Self-Care Centers Go To Premera Home Provider Directory Preferred Drug List Cool Tools ... Health A-Z You are here: Home Health A to Z Alport Syndrome Alport Syndrome Turkington, Carol A. Below: Definition Description Causes and symptoms Diagnosis ... Resources Definition A hereditary disease of the kidneys that primarily affects men, causing blood in the urine, hearing loss and eye problems. Eventually, kidney dialysis or transplant may be necessary. Description Alport syndrome affects about one in 5,000 Americans, striking men more often and severely than women. There are several varieties of the syndrome, some occurring in childhood and others not causing symptoms until men reach their 20s or 30s. All varieties of the syndrome are characterized by kidney disease that usually progresses to chronic kidney failure and by uremia (the presence of excessive amounts of urea and other waste products in the blood). Causes and symptoms Alport syndrome in most cases is caused by a defect in one or more genes located on the X chromosome. It is usually inherited from the mother, who is a normal carrier. However, in up to 20% of cases there is no family history of the disorder. In these cases, there appears to be a spontaneous genetic mutation causing Alport syndrome. Blood in the urine (hematuria) is a hallmark of Alport syndrome. Other symptoms that may appear in varying combinations include:

40. The National Kidney Foundation Of Illinois - JUST THE FACTS about alport syndrome What is alport syndrome? Because of the way alport syndromeis inherited, the disease tends to be more severe in men than in women. http://www.nkfi.org/factsheets/Alport2.html

National Kidney Foundation of Illinois, Inc. connecting you to JUST THE FACTS... about ALPORT SYNDROME What is Alport Syndrome? What are its symptoms? Alport Syndrome is an inherited disease that affects the glomeruli, the tiny blood vessels within the kidneys that filter the blood of its wastes. An English doctor, A. Cecil Alport, described many of the important features of the disease in the British Medical Journal in 1927, and his name has been associated with the disorder ever since. Because of the way Alport Syndrome is inherited, the disease tends to be more severe in men than in women. The central feature of the disease is the presence of blood in the urine. Boys with Alport Syndrome develop this symptom in infancy, while girls who carry the Alport gene may or may not have it. Another important symptom of Alport Syndrome is hearing loss. In boys with the disease, hearing loss is usually detectable by 8-10 years of age, and it may be severe enough to require the use of hearing aids. Hearing loss in girls tends to be much milder, rarely resulting in the need for hearing aids. Some boys with Alport Syndrome lose large amounts of protein in the urine, resulting in retention of fluid and body swelling. This condition is called the "nephrotic syndrome." With the passage of years, boys with Alport Syndrome develop the typical signs and symptoms of kidney failurehigh blood pressure, swelling, and in some cases, impaired growth.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 2     21-40 of 97    Back | 1  | 2  | 3  | 4  | 5  | Next 20