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         Anophthalmos:     more detail
  1. Microphthalmia and Anophthalmia: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Laith, M.D. Gulli, 2006

41. Eyeatlas - Online Atlas Of Ophthalmology
SLA Tilt Tilt Vertical dissociated deviation. GLOBE. anophthalmos anophthalmos.GLAUCOMA. Angle recession Glaucoma, Acute Glaucoma, Closure
http://www.eyeatlas.com/contents.htm
ANATOMY Eye anatomy
ANTERIOR CHAMBER Angle, Closure
Angle, Pigmentation

Anterior chamber IOL

Atalamia
...
Synchysis scintillans

CHOROID Angioid Streaks
CONJUNCTIVA Allergic conjunctivitis, Giant papillae
Allergic conjunctivitis, Giant papillae

Allergic conjunctivitis, Giant papillae

Amyloidosis
... Vernal conjunctivitis CORNEA Abrasion Abrasion Abrasion Alkali burn ... Wilson's disease EXTRAOCULAR MUSCLES Accomodative strabismus Accomodative strabismus Brown's syndrome Duane's syndrome ... Vertical dissociated deviation GLOBE Anophthalmos Anophthalmos GLAUCOMA Angle recession Glaucoma, Acute Glaucoma, Closure angle Glaucoma, Closure angle ... Trabeculectomy, Bleb INTRAOCULAR PRESSURE Bleb after trabeculectomy Glaucoma cupping Neovascular glaucoma Pseudoexfoliatio IRIS AND CILIARY BODY Aniridia Anisocoria Ciliary body adenoma Coloboma ... Wilson's disease LACRIMAL SYSTEM Canaliculitis Canaliculitis Dacryoadenitis Dacryocele ... Pseudocanaliculitis LENS Aphakia, Surgical Capsular fibrosis Capsular fibrosis Capsule rupture ... Pseudoexfoliatio lentis LID Allergy, Atropine

42. ClinicalTrials.gov - Linking Patients To Medical Research: Study Details
Condition. anophthalmos. Detailed Web Page. Publications. Sensi A, IncorvaiaC, Sebastiani A, Calzolari E. Clinical anophthalmos in a family. Clin Genet.
http://www.clinicaltrials.gov/ct/gui/show/NCT00011843?order=13

43. Anophthalmos From Ophthalmology / Globe
anophthalmos True or primary anophthalmos is very rare. Only when BackgroundTrue or primary anophthalmos is very rare. Only when
http://author.emedicine.com/OPH/topic572.htm
eMedicine Journal Ophthalmology Globe
Anophthalmos Author Information Introduction Clinical Differentials ... Bibliography
AUTHOR INFORMATION Section 1 of 11 Authored by Nick Mamalis, MD , Director of Ophthalmic Pathology, Director of Intermountain Ocular Research Center, Professor, Department of Ophthalmology, University of Utah School of Medicine Nick Mamalis, MD, is a member of the following medical societies: American Academy of Ophthalmology American Medical Association American Society of Cataract and Refractive Surgery , and Association for Research in Vision and Ophthalmology Edited by Ron W Pelton, MD, PhD , Consulting Staff, Department of Surgery, Memorial Hospital; Donald S Fong, MD, MPH , Assistant Clinical Professor of Ophthalmology, UCLA School of Medicine; Consulting Physician, Department of Ophthalmology, Southern California Permamente Medical Group; Mark T Duffy, MD, PhD Lance L Brown, OD, MD , Ophthalmologist, Regional Eye Center, Affiliated With Freeman Hospital and St John's Hospital, Joplin, Missouri; and Hampton Roy, Sr, MD

44. Anophthalmia And Microphthalmia Resource Guide
Other Names. anophthalmos and microphthalmos, small eye syndrome. What structures.Publishes a factsheet on anophthalmos and orbital implants.
http://www.nei.nih.gov/health/anoph/
Health Funding News Laboratories ... Health Information
Anophthalmia and Microphthalmia
On this page:
Related Topics:

The information provided in this Resource Guide was developed by the National Eye Institute to help patients and their families in searching for general information about anophthalmia and microphthalmia . An eye care professional who has examined the patient's eyes and is familiar with his or her medical history is the best person to answer specific questions.
Other Names
Anophthalmos and microphthalmos, small eye syndrome.
What are anophthalmia and microphthalmia?
Anophthalmia and microphthalmia are often used interchangeably. Microphthalmia is a disorder in which one or both eyes are abnormally small, while anophthalmia is the absence of one or both eyes. These rare disorders develop during pregnancy and can be associated with other birth defects.
What causes anophthalmia and microphthalmia?

45. USCAP - 91st Annual Meeting
History Eye removed postmortem from a female infant of 33 weeks gestationwith multiple congenital anomalies and apparent anophthalmos.
http://www.uscap.org/91st/optcase07.htm

OPHTHALMIC PATHOLOGY FOR THE NON-SPECIALIST
History

Eye removed post-mortem from a female infant of 33 weeks gestation with multiple congenital anomalies and apparent anophthalmos. Diagnosis
Microphthalmos, with corneal scarring and neovascularization dysgenesis of anterior segment cataract retinal dysplasia persistent hyperplastic primary vitreous Histopathology
There is parakeratosis of the corneal epithelium. Bowman's membrane is absent and there is scarring of the anterior stroma. Blood vessels are present in the anterior and mid-stroma. Descemet's membrane has formed but the trabecular meshwork is not recognizable. Both iris leaflets are markedly hypoplastic. The lens occupies much of the globe and there is posterior migration of the subcapsular epithelium with formation of bladder cells and also Morgagnian globules. There is a cyst of the pigmented ciliary epithelium on one side with posterior displacement of the ciliary processes. At the ora serrata non-pigmented ciliary epithelium is hyperplastic and has been drawn inwards behind the lens in a fibrovascular membrane. Between this membrane and the folded, dysplastic retina there is hemorrhage. The retinal pigment epithelium (RPE) shows focal reduplication. The sclera is unremarkable.
Slide 16

Anterior segment of eye with corneal scar, hypoplastic iris, cataractous lens and dysplastic retina.

46. Anophthalmos Related Search
anophthalmos Begin your search for. anophthalmos. anophthalmos searchGo! Search for other books. All Products.
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About Anophthalmos Touching the derivation of the name Anophthalmos, I confess
myself, with sorrow, equally at fault. Among a multitude of opinions
upon this delicate point- some acute, some learned, some sufficiently
the reverse I am able to select nothing which ought to be
considered satisfactory. Modified text originally written by Edgar Allan Poe.

47. Clinical Study: 01-HG-0094, Molecular Analysis Of Microphthalmia/Anophthalmia
Keywords Lenz Dysplasia Mental Retardation Microphthalmia/Anophthalmia MutationScreening Gene Characterization Conditions anophthalmos Investigational Drug(s
http://clinicalstudies.info.nih.gov/detail/A_2001-HG-0094.html
Protocol Number: 01-HG-0094
Title:
Molecular Analysis of Microphthalmia/Anophthalmia
Number:
01-HG-0094
Summary:
This study will try to learn more about the genetic cause and symptoms of microphthalmia (small eyes) or anophthalmia (absence of one or both eyes). Patients with microphthalmia or anophthalmia with mental retardation may be eligible for this study. Patients' parents and siblings will also be included for genetic studies. Patients may participate in both the clinical and laboratory parts of the study or just the laboratory part, as described below: Laboratory The laboratory study consists of DNA analysis to determine the genetic cause of microphthalmia/anophthalmia. The DNA sample is obtained using one of the following methods: -Blood draw - for young children, a numbing cream is applied to the skin before the needlestick to decrease the pain -Skin biopsy - a small piece of skin (about 1/8-inch in diameter) is removed surgically after the area has been numbed with an anesthetic -Cotton swab - a specimen is collected from inside the cheek using a cotton swab. This is done only for patients who cannot provide a blood or skin sample.

48. Enucleation, Evisceration And Exenteration
these criteria. GO TO TOP. Orbital Implants in anophthalmos. Implantscan be integrated or nonintegrated. Nonintegrated implants have
http://www.ophthalmic.hyperguides.com/Tutorials/oculoplastics/e_e_e/tutorial.asp
You've spent minutes on Ophthalmic Hyperguide
Enucleation, Evisceration and Exenteration Rodger Davies, MD
Introduction
The surgical procedure to remove an eye should be performed with efforts to minimize cosmetic deformity. The anophthalmic socket must be able to hold a prosthesis and allow movement of the prosthesis that matches the movements of the contralateral eye. The eyelids also must be positioned so their movement matches the contralateral eyelids. To achieve this, a socket with the following characteristics is required:
  • A centrally placed, buried, inert implant of adequate size attached to the extraocular muscles Deep fornices A lower eyelid that can support a prosthesis A superior eyelid with position and movement symmetric to the normal eyelid Prosthesis and implant volume equal to that of the natural eye An implant peg that couples with the prosthesis
These characteristics apply to both patients undergoing enucleation and patients undergoing evisceration. Many different implants and techniques can be used to meet these criteria.
Orbital Implants in Anophthalmos
Implants can be integrated or nonintegrated. Nonintegrated implants have no direct attachments to the extraocular muscles and are usually inert spheres of silicone or methylmethacrylate, placed in Tenon's capsule within the muscle cone, deep to anterior Tenon's fascia and conjunctiva. The rectus muscles may be sutured together anterior to the implant.

49. Congenital Anomalies Of The Eyelid, Orbit, And Lacrimal System
anophthalmos and Microphthalmos. anophthalmos results from abnormaldevelopment of optic vesicle. True anophthalmos is extremely rare.
http://www.ophthalmic.hyperguides.com/Tutorials/oculoplastics/congenital_anom/tu
You've spent minutes on Ophthalmic Hyperguide
Congenital Anomalies of the Eyelid, Orbit, and Lacrimal System Forrest J. Ellis, MD
Nasolacrimal Duct Obstruction
The development of the lacrimal drainage system begins at approximately 6 week's gestation. Canalization of the ectodermal cord begins during the third month in the area of the medial canthus. Canalization progresses toward the eyelid margin and toward the inferior meatus. The lacrimal puncta normally opens with eyelid separation during the seventh month of gestation. The distal lacrimal drainage system may not become patent until birth or shortly after birth. Blockage of the nasolacrimal system typically occurs in the distal portion where the tear duct opens into the nose beneath the inferior turbinate (Hasner valve). Because tears are not normally produced until a few weeks after birth, blockage of the lacrimal duct may not be recognized until several weeks after birth. Only about 1% to 6% of infants have symptomatic nasolacrimal duct obstruction. However, the majority of cases resolve by 1 year of age.

50. NSW Health - ICD-9-CM 740-759
743.0 anophthalmos 743.00 Clinical anophthalmos, unspecified Agenesis Congenitalabsence of eye anophthalmos NOS 743.03 Cystic eyeball, congenital 743.06
http://www.health.nsw.gov.au/public-health/icd/740-759.htm
14. CONGENITAL ANOMALIES (740-759)
740 Anencephalus and similar anomalies
  • Anencephalus Acrania Amyelencephalus Hemianencephaly Hemicephaly
  • Craniorachischisis
  • Iniencephaly
741 Spina bifida
    Excludes : spina bifida occulta (756.17) The following fifth-digit subclassification is for use with category 741: unspecified region 1 cervical region 2 dorsal (thoracic) region 3 lumbar region
  • With hydrocephalus Arnold-Chiari syndrome, type II Chiari malformation, type II Any condition classifiable to 741.9 with any condition classifiable to 742.3
  • Without mention of hydrocephalus Hydromeningocele (spinal) Hydromyelocele Meningocele (spinal) Meningomyelocele Myelocele Myelocystocele Rachischisis Spina bifida (aperta) Syringomyelocele
742 Other congenital anomalies of nervous system
  • Encephalocele Encephalocystocele Encephalomyelocele Hydroencephalocele Hydromeningocele, cranial Meningocele, cerebral Meningoencephalocele

51. Korean Standard Classification Of Diseases
Q11 anophthalmos, microphthalmos and macrophthalmos Q11.0 Cystic eyeball Q11.1Other anopthalmos Agenesis of eye Aplasia of eye Q11.2 Microphthalmos
http://www.nso.go.kr/eng/standards/edis/q11.htm
Q11 Anophthalmos, microphthalmos and macrophthalmos Q11.0 Cystic eyeball Q11.1 Other anopthalmos Agenesis of eye Aplasia of eye Q11.2 Microphthalmos Cryptophthalmos NOS Dysplasia of eye Hypoplasia of eye Rudimentary eye Exclusion £ºcryptophthalmos syndrome(Q87.0) Q11.3 Macrophthalmos Exclusion £ºmacrophthalmos in congenital glaucoma(Q15.0)

52. ICD-9-CM From Code 740
743 Congenital anomalies of eye 743.0 anophthalmos 743.00 Clinicalanophthalmos, unspecified Agenesis; Congenital absence of eye;
http://www.cpmc.columbia.edu/homepages/hripcsa/icd9/1tabular740.html
CONGENITAL ANOMALIES (740-759)
  • 740 Anencephalus and similar anomalies
    • 740.0 Anencephalus
      • Acrania
      • Amyelencephalus
      • Hemianencephaly
      • Hemicephaly
    • 740.1 Craniorachischisis
    • 740.2 Iniencephaly
  • 741 Spina bifida
    • Excludes: spina bifida occulta (756.17)
    • The following fifth-digit subclassification is for use with category 741:
      • 0 unspecified region
      • 1 cervical region
      • 2 dorsal (thoracic) region
      • 3 lumbar region
    • 741.0 With hydrocephalus
      • Arnold-Chiari syndrome, type II
      • Chiari malformation, type II
      • Any condition classifiable to 741.9 with any condition classifiable to 742.3
    • 741.9 Without mention of hydrocephalus
      • Hydromeningocele (spinal)
      • Hydromyelocele
      • Meningocele (spinal)
      • Meningomyelocele
      • Myelocele
      • Myelocystocele
      • Rachischisis
      • Spina bifida (aperta)
      • Syringomyelocele
    • 742 Other congenital anomalies of nervous system
      • 742.0 Encephalocele
        • Encephalocystocele
        • Encephalomyelocele
        • Hydroencephalocele
        • Hydromeningocele, cranial
        • Meningocele, cerebral
        • Meningoencephalocele
      • 742.1 Microcephalus
        • Hydromicrocephaly
        • Micrencephaly
      • 742.2 Reduction deformities of brain
        • Absence of part of brain
        • Agenesis of part of brain
        • Agyria
        • Aplasia of part of brain
        • Arhinencephaly
        • Holoprosencephaly
        • Hypoplasia of part of brain
        • Microgyria
      • 742.3 Congenital hydrocephalus

53. Umlslex.nlm.nih.gov/Lexicon/LEX_DB/SM.DB
anociassociation noun anocithesia noun anocithesia anocithesia noun anociassociation nounanophthalmia anophthalmia noun anophthalmos noun anophthalmos
http://umlslex.nlm.nih.gov/Lexicon/LEX_DB/SM.DB

54. ANOFTALMUS VE ANKILOBLEFARON FILIFORM ADNATUMUN BIRLIKTE BULUNDUGU BIR OLGU
case. Key Words anophthalmos, Ankyloblepharon filiforme adnatum. GIRIS.Göze olusturmustur. KAYNAKLAR. 1. Marchac D. anophthalmos. Current
http://lokman.cu.edu.tr/COD/Kongre95/metinler/21b-p014.htm
ANOFTALMUS VE ANKÝLOBLEFARON FÝLÝFORM ADNATUMUN BÝRLÝKTE BULUNDUÐU BÝR OLGU Uzm.Dr. Murat Yolar, Doç.Dr. Velittin Oðuz, Prof.Dr. Halit Pazarlý Ý.Ü. Cerrahpaþa Týp Fakültesi Göz Hastalýklarý A.B.D. ÖZET Amaç: Nadir konjenital anomalilerden olan anoftalmus ve ankiloblefaron filiform adnatuma ait özellikleri bir olgu dolayýsý ile irdelemektir. Metod: Müracaatýnda 7 günlük olan erkek olgu genel anestezi altýnda muayene edilmiþ, ultrasonografik ve bilgisayarlý tomografik incelemeleri ile sistemik ve genetik muayeneleri yapýlmýþtýr. Bulgular: Genel anestezi altýnda yapýlan muayenesinde bilateral olarak kapaklarýn son derece küçük olduðu; alt ve üst kapaklarýn birbirine ince bridler ile yapýþtýðý gözlendi. Kapaklar küçük bir müdahale ile birbirlerinden ayrýldý; ancak klinik, ultrasonografik ve tomografik incelemelerde her iki globa ait herhangi bir bulguya rastlanýlmadý. Sonuç: Ankiloblefaron filiform adnatum ile birlikte globlarýn bulunmayýþý olgunun baþlýca özelliðini oluþturmaktadýr. Anahtar Kelimeler: Anoftalmus, Ankiloblefaron filiform adnatum

55. EyePlastics: The Anophthalmic Socket (anophthalmos): Including Medpor, Enucluati
Definition. Anophthalmia is a medical term used to describe the absenceof the globe and ocular tissue from the orbit. This was first
http://www.eye-plastics.com/eyeplastics/anophthalmos.html
Definition Anophthalmia is a medical term used to describe the absence of the globe and ocular tissue from the orbit. This was first reported more than 400 years ago, yet it is only recently that significant reconstuctive options became available. There are many reasons why one might lose an eye.
Etiology Anophthalmia can be congenital (present at birth) or acquired later in life. Congenital anophthalmia can occur alone or along with other birth defects. Cases of anophthalmia may result from inherited genetic mutations, sporadic genetic mutations, chromosome abnormalities, prenatal environmental insult or unknown. born without eye. (Anophthalmia is very rare but the exact incidence is unknown. One report from a prospective study of 50,000 newborns found an incidence of microphthalmia of 0.22 per 1,000 live births) trauma infection tumor (such as retinoblastoma, choroidal malignant melanoma) advanced ocular disease (corneal disease, advanced resistant glaucoma)

56. MEANWHILE BACK IN IRAQ AND VIETNAM
I have not seen any reports on anophthalmos cases (babies born without eyes) associatedwith these compounds, but this data may well be in company files.
http://www.firethistime.org/meanwhileiniraq.htm
MEANWHILE....BACK IN IRAQ (and Vietnam)
"The Security Council began to streamline its vetting procedures in March 2000, when the total value of blocked contracts stood at about 1.7 billion dollars. In his letter, Sevan said a total of 1,854 contracts were now on hold, worth a total 4.956 billion dollars. They included orders for 4.28 billion dollars worth of humanitarian supplies and for 676 million dollars worth of oil industry equipment."
- from 'UN alarmed by contract blocking of Iraq oil-for-food programme,' reported by Agence France Press, 9th January 2002 "In 30 years in Washington I've never seen anything quite like it. They're being treated like enemies because of a policy disagreement." - Richard Perle, US Defense Policy Board Chairman and reiterated by former CIA Director James Woolsey, quoted in the Wall Street Journal, 10th January 2002 Perle was describing the US State Deptartment decision to suspend funding to the INC citing financial irregularities. The INC (Iraqi National Congress - in opposition to Saddam Hussein) had been pledged $97 million and were given a January 15th 2002 deadline to produce accounts. The State Department announcement came 10 days ahead of schedule. The INC informed them that undercover sources in Iraq would be compromised by full disclosure.
A CHAMBER OF HORRORS NEXT TO THE GARDEN OF EDEN
by
Andy Kershaw The Independent
1st December 2001
I thought I had a strong stomach - toughened by the minefields and foul frontline hospitals of Angola, by the handiwork of the death squads in Haiti and by the wholesale butchery of Rwanda. But I nearly lost my breakfast last week at the Basrah Maternity and Children's Hospital in southern Iraq.

57. ãÚáæãÇÊ Úä ÇáæßÇáÉ
shallow, reduced in anteroposterior diameter, with a small culde-sac and completelylined by conjunctiva with absence of both eyeballs (Bilateral anophthalmos
http://www.uruklink.net/iraqnews/echild.htm

58. Advances In Ophthalmology
to expand them. The goal is prosthetic eyes for Jacob. Jacob was bornwith a rare condition called anophthalmos. There is a total
http://www.kellogg.umich.edu/advances/transplant.html
Fall 2000
Lasers in Ophthalmology

Center Finds Link

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Content Submissions:
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rwallach@umich.edu

New Transplant Technique
Like any 2-year-old, Jacob Johnson has a bunch of bright white baby teeth, which he flashes frequently in a big smile. However, Jacob might never have been able to smile with his eyes, as well, had he not come to the Kellogg Eye Center for correction of a birth defect that left him without eyes. Last December, Christine C. Nelson, M.D., FACS, Associate Professor in the Department of Ophthalmology and Visual Sciences, performed surgery that will one day enable Jacob to flash his baby blues along with his smile. Jacob was born with a rare condition called anophthalmos While blindness cannot be helped, disfigurement can be essentially eliminated by the use of carefully created prosthetic eyes that are produced by an ocularist, a person who combines artistry and engineering. The ocularist works closely with the ophthalmologist and the patient to create life-like artificial eyes that fit and move comfortably within the sockets. In order to prepare for a cosmetically pleasing prosthesis, it is critical to stimulate the socket early so that it can enlarge to accommodate a series of artificial eyes as the baby moves through childhood. Experts advise that such a prosthesis must be in place by the age of two.

59. Eye Abnormalities
Coll. of Wisconsin; PAIRED BOX HOMEOTIC GENE 6; PAX6. anophthalmos SearchPUBMED for anophthalmos All Review Therapy Diagnosis. Blepharophimosis
http://www.ohsu.edu/cliniweb/C11/C11.250.html
Eye Abnormalities
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60. Clearinghouse:Publications
Birth Defects presented in all Annual reports are following Abdominal wall defects(others) Anencephaly anophthalmos / Microphthalmos Anorectal Atresia
http://www.icbd.org/publications.htm
ICBDMS Papers and Reports Updated February 07, 2003 Home Who/What Symposium Papers/Reports Members Web guide Questions Annual report 2000 ...
Pub Med

(National Library of Medicine)
Last September has been printed Annual report 2002 (with the data 2000) and
can be requested to the ICBD using the appropriate order form (7Kb;Word)
The Annual report 2001 (with the data 1999) will be available at the web as soon as possible. Birth Defects presented in all Annual reports are following:
Abdominal wall defects (others)
Anencephaly
Anophthalmos / Microphthalmos
Anorectal Atresia / Stenosis
Anotia / Microtia Arhinencephaly / Holoprosencephaly Bilateral renal agenesis Bladder Extrophy Choanal atresia, bilateral Cleft Lip Palate, with or without Cleft Palate Cleft Palate without Cleft Lip Cystyc Kidney (2) Diaphragmatic Hernia Encephalocele Epispadias Hydrocephaly Hypoplastic Left Heart Syndrome Hypospadias (1) Indeterminate sex Limb Reduction Defects Microcephaly Oesophageal Atresia / Stenosis, with or without fistula

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