41. Aplastic Anemia - Lucile Packard Children's Hospital Hematology Blood Disorders. aplastic anemia What is aplastic anemia? Whatcauses aplastic anemia? aplastic anemia in children has multiple causes. http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/hematology/aplsanem.html

Bone Marrow Transplantation Hematology Hematopoietic Stem Cell Transplantation Oncology ... Oncology Aplastic Anemia What is aplastic anemia? Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: red cells, white cells, and platelets. A reduced number of red blood cells causes the hemoglobin (a type of protein in the red blood cells that carries oxygen to the tissues of the body) to drop. A reduced number of white blood cells causes the patient to be susceptible to infection. A reduced number of platelets can cause the blood not to clot as easily. What causes aplastic anemia? Aplastic anemia in children has multiple causes. Some of these causes are idiopathic, meaning they occur sporadically for no known reason. Other causes are secondary, resulting from a previous illness or disorder. Nearly 50 to 75 percent of childhood cases of aplastic anemia occur sporadically for no known reason. Acquired causes, however, may include the following: history of specific infectious diseases such as hepatitis, Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus B19, or human immunodeficiency virus (HIV)

42. Aplastic Anemia In A Petrochemical Factory Worker aplastic anemia in a Petrochemical Factory Worker. Abstract A petrochemicalworker with aplastic anemia was referred to our hospital. http://ehpnet1.niehs.nih.gov/docs/1999/107p851-853baak/abstract.html

Environmental Health Perspectives Volume 107, Number 10, October 1999 Citation in PubMed Related Articles St. Mary's Hospital, The Catholic University of Korea Aplastic Anemia in a Petrochemical Factory Worker Young Mann Baak, Byoung Yong Ahn, Hwang Shin Chang, Ji Hong Kim, Kyoung Ah Kim, and Young Lim Department of Industrial Medicine, St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea Abstract A petrochemical worker with aplastic anemia was referred to our hospital. He worked in a petroleum resin-producing factory and had been exposed to low-level benzene while packaging the powder resin and pouring lime into a deactivation tank. According to the yearly environmental survey of the working area, the airborne benzene level was approximately 0.28 ppm. Exposure to benzene, a common chemical used widely in industry, may progressively lead to pancytopenia, aplastic anemia, and leukemia. The hematotoxicity of benzene is related to the amount and duration of exposure. Most risk predictions for benzene exposures have been based on rubber workers who were exposed to high concentrations. In the petroleum industry, the concentration of benzene is relatively low, and there are disputes over the toxicity of low-level benzene because of a lack of evidence. In this paper we report the case of aplastic anemia induced by low-level benzene exposure. Key words : aplastic anemia, benzene, petrochemical worker.

43. Johns Hopkins Kimmel Cancer Center aplastic anemia (AA) is the medical term for bone marrow failure. Severe aplasticanemia is a serious disorder requiring prompt medical attention. http://www.hopkinskimmelcancercenter.org/cancertypes/aplastic-anemia.cfm?canceri

44. Publications The aplastic anemia Controversy. What is the best therapy for the rare but deadlyblood disorder known as aplastic anemia? It depends on whom you ask. http://www.hopkinskimmelcancercenter.org/publications/publication.cfm?DocumentID

45. Blood Disorders - Aplastic Anemia - Methodist Health Care System, Houston, Texas aplastic anemia What is aplastic anemia? And, a reduced number of platelets causesthe blood not to clot as easily. What are the symptoms of aplastic anemia? http://www.methodisthealth.com/blood/aneaplas.htm

Blood Disorders Home Page Las Enfermedades de la Sangre (en español) Clinical Services Eileen Murphree McMillan Blood Center Center for Cell and Gene Therapy The Methodist Hospital's Hematology Service ... Transplantation Blood Disorders Anemia Types of Anemia Bleeding Disorders Hemochromatosis ... Appointment Aplastic Anemia What is aplastic anemia? Aplastic anemia occurs when the bone marrow produces too few of all three types of blood cells: red cells, white cells, and platelets. A reduced number of red blood cells causes hemoglobin to drop. A reduced number of white blood cells makes the patient susceptible to infection. And, a reduced number of platelets causes the blood not to clot as easily. What are the symptoms of aplastic anemia? The following are the most common symptoms for aplastic anemia, however, each individual may experience symptoms differently. headache dizziness nausea shortness of breath bruising The symptoms of anemia may resemble other blood disorders or medical problems. Consult your physician for a diagnosis.

46. Blood Disorders - Aplastic Anemia - Spanish Content - Methodist Health Care Syst Translate this page La Anemia Aplásica ¿Qué es la anemia aplásica? Qué causa laanemia aplásica? La anemia aplásica tiene múltiples causas. http://www.methodisthealth.com/spanish/blood/aneaplas.htm

Página Principal de las Enfermedades de la Sangre Servicios Clínicos Center for Cell and Gene Therapy The Methodist Hospital's Hematology Service Methodist Diagnostic Hospital ... El Trasplante de Médula Ósea Las Anemias Descripción General de la Anemia La Anemia Aplásica La Anemia por Deficiencia de Folato La Deficiencia de Glucosa-6-Fosfato Deshidrogenasa (su sigla en inglés es G6PD) ... La Trombocitemia Las Leucemias Descripción General de las Leucemias La Leucemia Linfocítica Aguda La Leucemia Linfocítica Crónica La Leucemia Mielógena Aguda ... La Leucemia Mielógena Crónica Los Linfomas La Enfermedad de Hodgkin El Linfoma no Hodgkin Glosario Recursos en la Red ... procedimiento Póngase en Contacto con Nosostros: Referencia Médica Plan Para Hacer una Cita Médica Preguntas Generales Planes de Salud ... Directorio de Médicos La Anemia Aplásica ¿Qué es la anemia aplásica? La anemia aplásica se presenta cuando la médula ósea produce muy poca cantidad de los tres tipos de células sanguíneas: glóbulos rojos, glóbulos blancos y plaquetas. Un número reducido de glóbulos rojos causa una baja en la hemoglobina. Un número reducido de glóbulos blancos hace al paciente susceptible a infecciones. Y un número reducido de plaquetas hace que la sangre no se coagule tan fácilmente. ¿Qué causa la anemia aplásica?

47. HealthlinkUSA Aplastic Anemia Links medical and health related topics. FindWhat. Click here for page 1of aplastic anemia information from the HealthlinkUSA directory. http://www.healthlinkusa.com/23ent.htm

48. Aplastic Anemia; Treatment, Prevention, Cure aplastic anemiaSearch information from many of the best aplastic anemia healthsites. aplastic anemia and Myleodysplastic Syndrome support list. http://www.healthlinkusa.com/content/23.html

Latest Health News Find Drug Information Health Calculators All Words Any Words A B C D ... Z Sunday, March 30, 2003 Alternative therapy struggles to bridge East-West divide Click here to read more Doctors are not following guidelines recommending flu and pneumonia vaccinations for hospitalized adults, leaving millions of elderly patients vulnerable to potentially deadly ailment Click here to read more A helping hand for uninsured; Agencies find ways to provide health care for area children Click here to read more The government has approved the first generic version of the acne drug, Accutane Click here to read more Gates to give India $100m for AIDS; Microsoft CEO begins controversy-laced trip to fight virus Click here to read more Allergies and Asthma Alternative Medicine Arthritis and Your Health ... Women's Health Sunday March 30, 2003 Spina Bifida: Spina Bifida is a rare birth disorder, affecting approximately 1 in 12-1400 live births. Click here to learn more Craniosynostosis: Sagittal Synostosis...males are affected about three times as often as females. Click here to learn more Spinal Cord Injury: Acts of violence have now overtaken falls as the second most common source of spinal cord injury.

49. APLASTIC ANEMIA aplastic anemia A severe lowering of the red blood cells (and white bloodcells) due to the failure of the bone marrow to produce more cells. http://www.medhelp.org/glossary2/new/GLS_0474.HTM

APLASTIC ANEMIA - A severe lowering of the red blood cells (and white blood cells ) due to the failure of the bone marrow to produce more cells . Often the result of chemotherapy . Some drugs can cause aplastic anemia as a side effect. Med Help Home Search Ask the Doctor Patient Network The medical glossary has been made possible by a generous donation from:

50. AIH And Aplastic Anemia Subject AIH and aplastic anemia Topic Area Misc. After a few months of monitoringthis, she was diagnosed with aplastic anemia after a bone marrow biopsy. http://www.medhelp.org/forums/hepatitis/messages/30200a.html

Advertisement Welcome to .... Questions in The Hepatitis Forum are being answered by doctors from Henry Ford Health System , consistently ranked one of the best hospitals in America. Subject: AIH and Aplastic Anemia Topic Area: Misc. Forum: The Hepatitis Forum Question Posted By: Michele on Thursday, March 16, 2000 I have a 13 yr old daughter that was diagnosed with Autoimmune Hepatitus 9 months ago. After treatment with Prednisone, she appears to be doing very well. During one of her blood tests though, her WBC count was alarmingly low. Her RBC and platelets were also low. After a few months of monitoring this, she was diagnosed with Aplastic anemia - after a bone marrow biopsy. I understand that certain viral hepatitus can cause this but my hemotologist and G.I. Specialist said a link could not be made with the AIH. I think it is too coincidental that two pretty rare idiopathic conditions could happen and not be linked in some way. Do you think there a connection? Answer Posted By: HFHSM.D.-D.M. on Sunday, March 19, 2000 Dear Michele: I appreciate your question. I can certainly imagine how concerned you are about your 13 year old daughter. As a general rule, I have to agree with your hematologist and gastroenterologist. I agree that both conditions are pretty unusual and it would be easy to think there would be a connection. In fact, there could well be a connection. I just am not sure what it is.

51. Diseases And Conditions -- Discovery Health -- Aplastic Anemia aplastic anemia is a condition in which the bone marrow fails to produceblood cells. aplastic anemia By Thomas Fisher, MD. Aplastic http://health.discovery.com/diseasesandcond/encyclopedia/533.html

aplastic anemia By Thomas Fisher, MD Aplastic anemia is a condition in which the bone marrow fails to produce blood cells. What is going on in the body? The bone marrow contains special cells known as stem cells. Stem cells are like infant cells. They may develop into red blood cells, white blood cells, and platelets. Red blood cells carry oxygen throughout the body. White blood cells fight infection. Platelets control bleeding by forming blood clots in certain situations. Blood cells have a limited life, so new ones are made constantly. Certain conditions can damage stem cells or change their environment. The stem cells stop making blood cells. The bone marrow fills up with fat, instead of developing blood cells. The low level of red blood cells, white blood cells, and platelets in the body is known as aplastic anemia. What are the signs and symptoms of the condition? A person with aplastic anemia may have the following symptoms: fatigue pale skin rapid heartbeat weakness What are the causes and risks of the condition? In 50% of the people with aplastic anemia, the cause is unknown. In other cases, the anemia may be caused by one of the following factors:

52. Aplastic Anemia - Cambridge University Press Home Catalogue aplastic anemia. Related Areas aplastic anemia. Pathophysiologyand Treatment. Edited by Hubert Schrezenmeier, Andrea Bacigalupo. £90.00. http://books.cambridge.org/0521641012.htm

Home Catalogue Related Areas: Medicine New titles Email For updates on new titles in: Medicine Aplastic Anemia Pathophysiology and Treatment Edited by Hubert Schrezenmeier, Andrea Bacigalupo In stock Reviews ‘This book provide a comprehensive and up to date concepts on the pathophysiology, epidemiology, diagnosis and treatment of acquired and inherited aplastic anemia. The book is an excellent and enjoyable to read. The amateur who is satisfied with certainty will drive more from it than the impartial professional seeking and challenge. For the mahority of doctors and especially human hematologists, the book succeeds as an example of the precept ‘first do not harm’. Aplastic Anemia is a super textbook and should be in the library of every scientist interested in this subject. I would also suggest the book to medical students.’Professor Pio Conti Aplastic Anemia is a super textbook and should be in the library of every scientist interested in this subject. I would also suggest the book to medical students.’Professor Pio Conti, International Journal of Immunopathology and Pharmacology Aplastic Anemia will be a useful reference work for clinicians who deal with this disorder and will be a good source of background information for those conducting basic research on the mechanisms.’Journal of the Royal Society of Medicine

53. Aplastic Anemia aplastic anemia Guide picks. A fatal, noncontagious bone marrow failure. LRFaplastic anemia Information from the Leukaemia Research Fund (UK). http://rarediseases.about.com/cs/aplasticanemia/

zfp=-1 About Rare/Orphan Diseases Search in this topic on About on the Web in Products Web Hosting Rare/Orphan Diseases with Mary Kugler Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects BUYER'S GUIDE Before You Buy Top Picks Sites for Online Specialty Shopping ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Aplastic anemia Guide picks A fatal, non-contagious bone marrow failure. LRF: Aplastic Anemia Information from the Leukaemia Research Fund (UK). NORD: Aplastic Anemia Brief definition of the disorder, with links, from the National Organization for Rare Disorders. Aplastic Anemia Answer Book Comprehensive information from the Medical Education Information Center (MEdIC) at the University of Texas - Houston. Offers services, educational materials, FAQs, research studies, and news. Aplastic Anemia Central Personal site offers numerous links to Internet resources related to the disorder. Clinical Study at NHLBI Description of a study at the National Heart, Lung, and Blood Institute on aplastic anemia, and information on how to be part of it. Introduction for the General Physician Medical information about aplastic anemia from the Medical Education Information Center (MEdIC) at the University of Texas - Houston.

54. ICT - More About Aplastic Anemia aplastic anemia. More About aplastic anemia. Aplastic radiation. Aplasticanemia most commonly affects adolescents and young adults. http://ict.louisville.edu/bedside/aa/whatis.html

More About Aplastic Anemia Aplastic Anemia is classified as a bone marrow disorder caused by the deficiency of the production of red blood cells. The cause of aplastic anemia is usually not known, but a small number of cases may be caused by exposure to chemical and antineoplastic agents and ionizing radiation. Aplastic anemia most commonly affects adolescents and young adults. Infiltration of cells into the bone marrow that are not normally present in bone marrow can interfere with normal blood production. Aplastic anemia may be acute or chronic, but it will always progress. Patients with aplastic anemia learn to take steps to prevent infections and to get adequate rest. When the platelet count becomes too low ( <20,000/mm3), steps are taken to prevent bleeding: not shaving with a razor, humidifying to prevent dry mucous membranes and using stool softeners and a healthy diet to promote regular bowel movements. Patients can check for bleeding early by checking for blood in urine and stools using a chemical test and by examining the skin for petechiae and ecchymoses . A diet high in vitamins and proteins is recommended. Individuals with aplastic anemia may be treated with either bone marrow transplantation or immunosuppressive agents.

55. Childrens Severe Aplastic Anemia aplastic anemia. What is aplastic anemia? Aplastic easily. What causesaplastic anemia? aplastic anemia in children has multiple causes. http://www.chw.org/Templates/PPF/ParentID/1849/NID/1849/PageID/1856/Greystone.as

Anemia Aplastic Anemia Hemolytic Anemia Iron Deficiency Anemia ... Blood Disorders Aplastic Anemia in Children What is aplastic anemia? Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: red cells, white cells and platelets. A reduced number of red blood cells causes the hemoglobin (a type of protein in the red blood cells that carries oxygen to the tissues of the body) to drop. A reduced number of white blood cells causes the patient to be susceptible to infection. A reduced number of platelets can cause the blood not to clot as easily. What causes aplastic anemia? Aplastic anemia in children has multiple causes. Some of these causes are idiopathic, meaning they occur sporadically for no known reason. Other causes are secondary, resulting from a previous illness or disorder. Nearly 50 to 75 percent of childhood cases of aplastic anemia occur sporadically for no known reason. Acquired causes, however, may include: History of specific infectious diseases such as hepatitis, Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus B19, or human immunodeficiency virus (HIV).

56. ThirdAge - Adam - Secondary Aplastic Anemia Secondary aplastic anemia. Secondary aplastic anemia is a failure of the bloodcellforming capacity of the bone marrow that affects all blood-cell types. http://www.thirdage.com/health/adam/ency/article/000529.htm

document.write(''); document.write(''); document.write('<'); document.write('/SCRIPT>'); document.write(''); document.write(''); document.write('<'); document.write('/A>'); document.write('<'); document.write('/NOSCRIPT>'); document.write('<'); document.write('/IFRAME>'); Activities Computers Family Tree Health ... Prevention Secondary aplastic anemia Definition: Secondary aplastic anemia is a failure of the blood-cell forming capacity of the bone marrow that affects all blood-cell types. Alternative Names: Anemia - secondary aplastic; Acquired aplastic anemia Causes, incidence, and risk factors: Secondary aplastic anemia is a condition that is a result of injury to the stem cell, a cell that gives rise to other blood cell types when it divides and differentiates. Consequently, there is a reduction in all types of blood cells: red blood cells, white blood cells, and platelets (which is called pancytopenia). Causes of secondary aplastic anemia include chemotherapy , drug therapy to suppress the immune system, radiation therapy toxins such as benzene or arsenic, drugs

57. ThirdAge - Adam - Idiopathic Aplastic Anemia Idiopathic aplastic anemia. Definition Idiopathic aplastic anemia is a failure ofthe bone marrow to properly form all types of blood cells. Alternative Names http://www.thirdage.com/health/adam/ency/article/000554.htm

document.write(''); document.write(''); document.write('<'); document.write('/SCRIPT>'); document.write(''); document.write(''); document.write('<'); document.write('/A>'); document.write('<'); document.write('/NOSCRIPT>'); document.write('<'); document.write('/IFRAME>'); Activities Computers Family Tree Health ... Prevention Idiopathic aplastic anemia Definition: Idiopathic aplastic anemia is a failure of the bone marrow to properly form all types of blood cells. Alternative Names: Anemia - idiopathic aplastic Causes, incidence, and risk factors: Idiopathic aplastic anemia is a condition that results from injury to the stem cell, a cell that gives rise to other cell types after it divides. Consequently, there is a reduction in all cell types red blood cells, white blood cells and platelets with this type of anemia , which is called pancytopenia. The cause of idiopathic aplastic anemia is unknown, but is thought to be an autoimmune process (the body reacting against its own cells). Causes of other types of aplastic anemia may be chemotherapy radiation therapy toxins , drugs, pregnancy , congenital disorder, or systemic lupus erythematosus Symptoms arise as the consequence of bone marrow failure. Anemia (low

58. Hematology & Blood Disorders - Aplastic Anemia Always consult your physician for a diagnosis. aplastic anemia. What is aplasticanemia? What causes aplastic anemia? aplastic anemia has multiple causes. http://www.viahealth.org/disease/blood/aneaplas.htm

ViaHealth Disease and Wellness Information ViaHealth's Hematology Services Laboratories Cancer Care Heart Care What is anemia? Anemia is a common blood disorder, which is caused when there is a drop in hemoglobin or hematocrit in the blood. Hemoglobin is the part of blood that distributes oxygen from the lungs to tissues in the body. Hematocrit is the measurement of the percentage of red blood cells found in a specific volume of blood. Anemia is usually a symptom of a disease rather than a disease itself. Anemia may be a symptom of another disease. The following are the most common symptoms of anemia. However, each individual may experience symptoms differently. Symptoms may include: abnormal paleness or lack of color of the skin increased heart rate (tachycardia) breathlessness, or difficulty catching a breath (dyspnea) lack of energy, or tiring easily (fatigue) dizziness, or vertigo, especially when standing

59. MEL: Aplastic Anemia aplastic anemia. AA providers. aplastic anemia Central; aplastic anemiaFoundation of America; aplastic anemia Association of Canada; http://mel.lib.mi.us/health/health-aplastic.html

Michigan.gov Home HAL Home MeL Internet MeL Magazines and eBooks Health Information Resources About the Health Collection Back to the Health Index Medline Evaluating Health Information ... Michigan Health and Hospitals Aplastic Anemia AA-MDS-TALK , an electronic mailing list in support of Aplastic Anemia (AA) and Myelodysplastic Syndromes (MDS) patients, friends, families, and care providers. Aplastic Anemia Central Aplastic Anemia Foundation of America Aplastic Anemia Association of Canada Johns Hopkings Oncology Center Aplastic Anemia page ... MEL Cancer Index Page Selector and Collection Librarian: Metta Lansdale ( lansdale@mel.org The Health Information Resources section of the Michigan Electronic Library (MEL) provides resources for informational purposes. Health information should always be carefully reviewed with your health care provider. This service is funded in part by the State of Michigan through the Library of Michigan. Additional project support comes from the federal Library Services and Technology Act (LSTA) via the Institute of Museum and Library Services (IMLS) http://mel.org/health/health-aplastic.html

60. Aplastic Anemia - Evaluation, Treatment And Research At The National Heart, Lung The National Heart, Lung and Blood Institute is actively seeking patients withaplastic anemia to receive free evaluation and/or treatment in our clinical http://patientrecruitment.nhlbi.nih.gov/AplasticAnemia.aspx

Patient Recruitment Home Patient Recruitment - Aplastic Anemia Research Studies Immunosuppression for Aplastic Anemia Aplastic Anemia Research Study Immunosuppression for Aplastic Anemia Aplastic anemia results from failure of the bone marrow to make a normal quantity of red blood cells, and may be treated by drugs that suppress the immune system. For patients with severe aplastic anemia, we offer a combination of antithymocyte globulin plus cyclosporine combined with a new drug call mycophenolate mofetil. Our goal is to decrease the risk of relapse and of late complications. To be eligible, patients cannot previously have received immunosuppressive therapies. For moderate aplastic anemia, we offer patients therapy with a monoclonal antibody that recognizes activated T lymphocytes. This therapy does not require hospitalization and has very few of side effects. Eligible patients are not asked to pay for their medical treatment and hospital costs. For more information, please contact the Patient Recruitment and Public Liaison Office at 1-800-411-1222 or email: prpl@mail.cc.nih.gov

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