1. Beryllium Disease Prevention Program At Lawrence Livermore National Laboratory Resources, program information and FAQs from Lawrence Livermore National Laboratory.Category Health Occupational Health and Safety Beryllium......LLNL's beryllium disease Prevention Program is part of longstandingberyllium control efforts here that predate any federal mandates. http://www.llnl.gov/Be-prevention/home.html

Home Facts Medical Surveillance Regulations ... Training Administration: Health Services Hazards Control LLNL's Beryllium Disease Prevention Program is part of long-standing beryllium control efforts here that predate any federal mandates. These controls, plus a high level of awareness of the hazards of beryllium among scientists, engineers, technicians and other staff who work in areas where beryllium is used, have resulted in a low beryllium disease rate at LLNL. Although solid beryllium poses no health hazard, inhaling beryllium particulates (such as dust, mists, or welding fumes) can produce acute or chronic lung disease. Skin irritation may result from direct contact with soluble beryllium compounds, and healing is impaired in beryllium-contaminated wounds. LLNL's Beryllium Disease Prevention Program addresses a new DOE effort designed to reduce the number of workers exposed to beryllium, minimize the levels of beryllium exposure, and ensure early detection of beryllium-related disease. LLNL's control program consists of: workplace evaluations and establishment of controls training medical surveillance Implementation of the Chronic Beryllium Disease Prevention Program Requirements " contains a complete description of LLNL's implementation program.

2. ATSDR - ToxFAQs: Beryllium This fact sheet answers the most frequently asked health questions (FAQs) about beryllium. For more information, call the ATSDR Information Center at 1888-422-8737. air become sensitive to beryllium and may develop chronic beryllium disease (CBD), an irreversible and sometimes fatal http://www.atsdr.cdc.gov/tfacts4.html

Search Index Home Glossary ... Contact Us RELATED RESOURCES PDF for Printing (See PDF Info) Public Health Statement Toxicological Profile CONTENTS Highlights What is it? What happens to it in the environment? How might I be exposed to it? ... More external safety and chemistry information ATSDR RESOURCES Minimal Risk Levels Division of Toxicology PROFILE HOMEPAGES Toxicological Profiles Public Health Statements ToxFAQs Beryllium CAS# September 2002 This fact sheet answers the most frequently asked health questions (FAQs) about beryllium. For more information, call the ATSDR Information Center at 1-888-422-8737. This fact sheet is one in a series of summaries about hazardous substances and their health effects. It is important you understand this information because this substance may harm you. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. HIGHLIGHTS: People working or living near beryllium industries have the greatest potential for exposure to beryllium. Lung damage has been observed in people exposed to high levels of beryllium in the air. About 1-15% of all people occupationally-exposed to beryllium in air become sensitive to beryllium and may develop chronic beryllium disease (CBD), an irreversible and sometimes fatal scarring of the lungs. CBD may be completely asymptomatic or begin with coughing, chest pain, shortness of breath, weakness, and/or fatigue. Beryllium has been found in at least 535 of the 1,613 National Priorities List sites identified by the Environmental Protection Agency (EPA).

3. Department Of Energy Chronic Beryllium Disease Prevention Program US Department of Energy information on disease preventive workshops.Category Health Occupational Health and Safety Beryllium...... Part III. Department of Energy. 10CFR Part 850 Chronic beryllium disease PreventionProgram; Final Rule. Wednesday December 8, 1999. CLARIFICATIONS, INTERPRETATIONS. http://tis.eh.doe.gov/be/

Part III Department of Energy 10CFR Part 850 Chronic Beryllium Disease Prevention Program; Final Rule Wednesday December 8, 1999 CLARIFICATIONS INTERPRETATIONS AIHA announces Beryllium Proficiency Testing Program Availability (February 2003) Beryllium Sensitivity/Chronic Beryllium Disease Testing for Current Department of Energy (DOE)/DOE Contractor Employees (February 2003) Sites with CBDPP CBDPP Points of Contact Office of Worker Advocacy Former Workers Program ... Beryllium Compensation

4. Med Facts-Medfacts-National Jewish Medical And Research Center in the development of a scarring lung disease, chronic beryllium disease (CBD). CBD results from an allergic response; http://www.nationaljewish.org/medfacts/beryllium_medfact.html

FACTS ABOUT BERYLLIUM DISEASE What is Beryllium? Beryllium is a naturally occurring metal which is found in beryl and bertrandite rock. It is extremely lightweight and hard, is a good electrical and thermal conductor and is non-magnetic. These properties make beryllium suitable for use in many industries, which include: Metal working (pure beryllium, copper and aluminum alloys, jet brake pads, aerospace components) Ceramic manufacturing (semi-conductor chips, ignition modules, crucibles, jet engine blades, rocket covers) Electronics (transistors, heat sinks, x-ray windows) Atomic energy industry (heat shields, nuclear reactors, nuclear weapons) Laboratory work (research and development, metallurgy, chemistry) Extraction (ore and scrap metal) Dental work (alloys in crowns, bridges, dental plates) Prior to 1951, it was used in fluorescent lamp work. What is Beryllium Disease (Berylliosis)? Beryllium disease primarily affects the lungs. The disease occurs when people inhale beryllium dust or fumes. Skin disease with poor wound healing and rash or wart-like bumps can also occur. A person can develop beryllium disease even after being away from the beryllium industry for many years. There are two forms of beryllium disease: Acute Beryllium Disease usually has a quick onset and resembles pneumonia or bronchitis. It is now rare due to improved industrial protective measures designed to reduce beryllium exposure levels.

5. The Natural History Of Beryllium Sensitization And Chronic Beryllium Disease who are sensitized to beryllium and those who have chronic beryllium disease (CBD) with lung pathology and impairment. http://ehpnet1.niehs.nih.gov/docs/1996/Suppl-5/newm

Conference on Beryllium-related Diseases Environmental Health Perspectives 104, Supplement 5, October 1996 Citation in PubMed Related Articles The Natural History of Beryllium Sensitization and Chronic Beryllium Disease Lee S. Newman, Jenifer Lloyd, and Elaine Daniloff Departmet of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado; Department of Medicine and Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado Abstract Environ Health Perspect 104(Suppl 5):937-943 (1996) Key words: beryllium, chronic beryllium disease, granuloma, cell-mediated immunity, lymphocyte, natural history, lung disease, pulmonary, immunology, metal toxicity This paper was presented at the Conference on Beryllium-related Diseases held 8-10 November 1994 in the Research Triangle Park, North Carolina. Manuscript received 29 April 1996; manuscript accepted 1 May 1996. Address correspondence to Dr. S. Newman, National Jewish Center for Immunology and Respiratory Medicine, 1400 Jackson Street, Room D-104, Denver, CO 80206. Telephone: (303) 398-1725. Fax: (303) 398-1851. E-mail: newmanl@njc.org

6. Med Facts-Medfacts-National Jewish Medical And Research Center Fact sheet by National Jewish Medical and Research Center. http://nationaljewish.org/medfacts/beryllium_medfact.html

FACTS ABOUT BERYLLIUM DISEASE What is Beryllium? Beryllium is a naturally occurring metal which is found in beryl and bertrandite rock. It is extremely lightweight and hard, is a good electrical and thermal conductor and is non-magnetic. These properties make beryllium suitable for use in many industries, which include: Metal working (pure beryllium, copper and aluminum alloys, jet brake pads, aerospace components) Ceramic manufacturing (semi-conductor chips, ignition modules, crucibles, jet engine blades, rocket covers) Electronics (transistors, heat sinks, x-ray windows) Atomic energy industry (heat shields, nuclear reactors, nuclear weapons) Laboratory work (research and development, metallurgy, chemistry) Extraction (ore and scrap metal) Dental work (alloys in crowns, bridges, dental plates) Prior to 1951, it was used in fluorescent lamp work. What is Beryllium Disease (Berylliosis)? Beryllium disease primarily affects the lungs. The disease occurs when people inhale beryllium dust or fumes. Skin disease with poor wound healing and rash or wart-like bumps can also occur. A person can develop beryllium disease even after being away from the beryllium industry for many years. There are two forms of beryllium disease: Acute Beryllium Disease usually has a quick onset and resembles pneumonia or bronchitis. It is now rare due to improved industrial protective measures designed to reduce beryllium exposure levels.

7. Department Of Energy Chronic Beryllium Disease Prevention Program Provides fact sheets and articles about the incurable disease, plus details about government regulations regarding exposure to beryllium. and control of beryllium. To provide current and historical information of the nature of this disease and its effects http://tis-nt.eh.doe.gov/be

Part III Department of Energy 10CFR Part 850 Chronic Beryllium Disease Prevention Program; Final Rule Wednesday December 8, 1999 CLARIFICATIONS INTERPRETATIONS AIHA announces Beryllium Proficiency Testing Program Availability (February 2003) Beryllium Sensitivity/Chronic Beryllium Disease Testing for Current Department of Energy (DOE)/DOE Contractor Employees (February 2003) Sites with CBDPP CBDPP Points of Contact Office of Worker Advocacy Former Workers Program ... Beryllium Compensation

8. Chronic Beryllium Disease For First Time in 40 Years National Jewish Researchers Report Chronicberyllium disease Caused by Extremely Low Levels of Exposure http://www.nationaljewish.org/news/balkissoonbercop.html

nurses answer your questions by E-mail! For First Time in 40 Years National Jewish Researchers Report Chronic Beryllium Disease Caused by Extremely Low Levels of Exposure DENVER-Exposure to extremely low levels of a lightweight metal commonly used to make everything from nuclear weapons to golf clubs has been shown to cause chronic beryllium disease (CBD) in workers who manufacture these products, according to National Jewish Medical and Research Center physicians. Investigators at National Jewish reported cases of CBD occurring in two people working with 2 percent beryllium copper alloy, according to the current issue of the Journal of Occupational and Environmental Medicine . CBD caused by 2 percent beryllium copper alloy was last described in the U.S. medical literature more than 40 years ago. "From the 1930s to the present, there have been people in industry and academics who have implied that these types of alloys with less than 2 percent beryllium content are safe," said Ronald C. Balkissoon, M.D.

9. Document 14.4 - Implementation Of The Chronic Beryllium Disease Prevention Progr Document 14.4. Implementation of the Chronic beryllium disease PreventionProgram Requirements. Formerly 2.1 Acute beryllium disease. Acute http://www.llnl.gov/es_and_h/hsm/doc_14.04/doc14-04.html

Part 14: Chemical Document 14.4 Implementation of the Chronic Beryllium Disease Prevention Program Requirements Revision Definitions Revision History Approval date: August 1, 2001 Table of Contents 1.0 Introduction 1.1 Goals 1.2 Applicability 2.0 Hazards ... 6.3 Other Sources Appendices Appendix A Acronyms, Terms, and Definitions Appendix B Medical Protection Requirements for Current and Prospective Beryllium Workers Appendix C Statistical Analysis of Beryllium Data Tables Table 1. Beryllium concentrations in soils. Table 2. Occupational exposure, housekeeping, and release standards. Table 3. Required training. Table 4. Required respiratory protection. ... Table 5. Beryllium emergency response actions. Figures Figure 1. Access posting for entrance to beryllium work areas. Figure 2. Access sign for regulated beryllium work areas. Figure 3. Label for containers of beryllium or items contaminated with beryllium. Figure 4. Label for beryllium items. ... Figure 6. Beryllium storage area sign. 1.0 Introduction Beryllium metal, alloys, and compounds are widely used at LLNL and other Department of Energy (DOE) facilities because of the materials' nuclear properties as a moderator (i.e., reflector) of neutrons. Favorable mechanical properties have also resulted in beryllium's widespread use in the aerospace industry. Addition of 2% or less beryllium to copper forms an alloy with high strength and hardnessproperties that have made the alloy useful in electronics, automotive, defense, and aerospace industries worldwide. Beryllium oxide (also known as beryllia) can be formed into beryllia ceramics, which have an exceptional combination of high thermal conductivity, electrical resistivity, and dielectric properties and which are used widely in electronics, laser, automotive, and defense applications.

10. Beryllium Disease - Golomb & Honik Law firm offers consumer information on the effects of exposure to beryllium, which can lead to lung damage. Symptoms include shortness of breath, fever, and fatigue. http://redirect-west.inktomi.com/click?u=http://www.looksmart.com/og/pr%3Dcdd%3B

11. Chronic Beryllium Disease Chronic beryllium disease. Exposure to beryllium in the workplace can result inthe development of a scarring lung disease, chronic beryllium disease (CBD). http://www.njc.org/deoh/acr14.html

Chronic Beryllium Disease Exposure to beryllium in the workplace can result in the development of a scarring lung disease, chronic beryllium disease (CBD). CBD results from an allergic response; a test is available which can detect those with the allergic response, prompting clinical evaluation and diagnosis, often before symptoms are apparent. Onset of this disease may be very slow with first symptoms including cough, shortness of breath, fatigue, fevers and night sweats. From 1-6% of exposed workers will eventually develop this disease within months after first exposure while others may develop it years after exposure has ceased. Although highly exposed workers may be at greater risk of developing CBD, it can occur in those with only brief or low levels of exposure. OVERVIEW Team Leaders CLINICAL and PREVENTIVE SERVICES Beryllium Sensitization Screening and Surveillance Diagnosis and Treatment INDUSTRIAL HYGIENE SERVICES Exposure Sampling Control and Monitoring Systems Consulting and Planning Employee Education and Risk Management RISK SURVEILLANCE PROGRAM CONTACT INFORMATION See related information: Personal Respiratory Protection Program (PDF format, requires

12. Chronic Beryllium Disease: Uncommon Disease, Less Common Diagnosis Abstract. Chronic beryllium disease (CBD) is typically considered only when occupational exposure to beryllium is a http://ehpnet1.niehs.nih.gov/docs/1998/106p765-767middleton/abstract.html

Environmental Health Perspectives Volume 106, Number 12, December 1998 Citation in PubMed Related Articles Chronic Beryllium Disease: Uncommon Disease, Less Common Diagnosis Dannie C. Middleton Health Investigations Branch, Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333 USA Abstract Key words : berylliosis, beryllium, granulomatous, hypersensitive, lymphocyte, pulmonary, sarcoidosis. Environ Health Perspect 106:765-767 (1998). [Online 2 November 1998] http://ehpnet1.niehs.nih.gov/docs/1998/106p765-767middleton/abstract.html Address correspondence to D.C. Middleton, Health Investigations Branch, Division of Health Studies, Agency for Toxic Substances and Disease Registry, 1600 Clifton Road MS E31, Atlanta, GA 30333 USA. I thank Mary C. White and Myron G. Schultz for advice and encouragement during the preparation of this manuscript. Received 15 May 1998; accepted 16 July 1998. Table of Contents Full Article Citation in PubMed Related Articles Last Update: November 2, 1998

13. Chronic Beryllium Disease Conference At National Jewish Medical And Research Medical Personnel to Hear beryllium disease Expert Dr. Lee Newman at NationalJewish Medical and Research Center January 911, 2002. Health News Home. http://www.njc.org/news/beryllium_conference_2001.html

September 12, 2002 Contact: William Allstetter allstetterw@njc.org Medical Personnel to Hear Beryllium Disease Expert Dr. Lee Newman at National Jewish Medical and Research Center January 9-11, 2002 Health News Home National Jewish Home Health-E-News Subscribe to our newsletter DENVER - Exposure to beryllium, found in a wide variety of industries, can put workers at risk of developing Chronic Beryllium Disease (CBD), a debilitating lung condition that can be controlled if found in its early stages. National Jewish Medical and Research Center's internationally known expert on CBD, Lee Newman , M.D., will lead a three-day conference on the newest developments in surveillance, diagnosis, and treatment of the disease January 9-11, 2002, at National Jewish in Denver. Medical staff from across the United States and Canada involved in the surveillance, diagnosis and clinical management of patients with beryllium sensitization and CBD - including pulmonologists, primary care physicians, industrial hygienists, and health and safety managers of facilities that use beryllium -

14. Beryllium Support Group Support group for chronic beryllium disease. http://www.dimensional.com/~mhj/index.html

B eryllium S upport G roup Home Overview Contact Announcements ... Search Overview This web site was formally launched on March 12, 1996 by Michael Jackson a member of the Beryllium Support Group which meets monthly at the National Jewish Medical and Research Center in Denver, Colorado. The intent is to provide a platform where any other Beryllium Support Group regardless of affiliation or location can freely participate in the presentation of or transfer of information relating to this incurable disease. Some of the goals of this site is to provide a means: To provide a forum where anyone around the country or the world can obtain information or provide information they have experienced as a result of this disease. To provide current and historical information on studies and papers relating to this disease. To provide current and historical information relating to the health risks of using beryllium. To provide current and historical information relating to regulations governing the use and control of beryllium. To provide current and historical information of the nature of this disease and its effects on the human body.

15. ABCNEWS.com : 20/20: Beryllium Dust Causes Chronic Disease Renwand is a victim of Chronic beryllium disease (CBD), an incurable lung disease also known as berylliosis. http://www.abcnews.go.com/onair/2020/2020_000419_beryllium_feature.html

GO Kids GO Family GO Money GO Sports ... GO Home ABCNEWS WEB ABOUT GO NETWORK SIGN IN FREE E-MAIL HOME NEWS SUMMARY U.S. POLITICS WORLD BUSINESS TECHNOLOGY SCIENCE TRAVEL ESPN SPORTS ENTERTAINMENT WEATHER.com REFERENCE LOCAL ABCNEWS ON TV World News GMA Nightline This Week ... ABC News Store SEARCH ABC.com EMAIL ABCNEWS.com SEND PAGE TO A FRIEND TOOLS AND HELPERS The Deadly Dust Thousands At Risk of Chronic Beryllium Disease After years of working with beryllium, Gary Renwand, 62, now suffers from an incurable lung illness. (ABCNEWS.com) By Amiel Weisfogel April 19 Renwand is a victim of Chronic Beryllium Disease (CBD), an incurable lung disease also known as berylliosis. It is very much the same for Joel Van Dyke, 53, who lives in the mountains of Colorado. He worked for a company that used beryllium to make missile parts. Now he too is dying from CBD and carries on with the help of oxygen at all hours of the day. Military Priorities vs. Safety Many workers may have become sick because of a deal between the government and the industry that ensured the steady supply of beryllium for American weapons. In solid form, it is harmless; but once cut or ground, beryllium dust can be deadly. At least 1,200 people who have breathed in beryllium dust have contracted CBD.

16. The Inside Story Beryllium Disease beryllium disease Page 1 2 3 search 6,500 (Read the document.beryllium disease is not limited to workers. Neighborhood cases http://www.chemicalindustryarchives.org/dirtysecrets/beryllium/1.asp

17. Significance Of The Blood Beryllium Lymphocyte Proliferation Test Abstract An in vitro measure of the beryllium antigenspecific cell-mediated immune response. This response to beryllium is now understood to play a central role in the immunopathogenesis of chronic beryllium disease (CBD). http://ehpnet1.niehs.nih.gov/docs/1996/Suppl-5/lsnewmanabs.html

Conference on Beryllium-related Diseases Environmental Health Perspectives 104, Supplement 5, October 1996 Citation in PubMed Related Articles Significance of the Blood Beryllium Lymphocyte Proliferation Test Lee S. Newman Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, and University of Colorado Health Sciences Center, Denver, Colorado Abstract The blood beryllium lymphocyte proliferation test (BeLPT) is an in vitro Environ Health Perspect 104(Suppl 5):953-956 (1996) Key words: beryllium, chronic beryllium disease, granuloma, cell-mediated immunity, lymphocyte, lung disease, pulmonary, immunology, metal toxicity This paper was presented at the Conference on Beryllium-related Diseases held 8-10 November 1994 in the Research Triangle Park, North Carolina. Manuscript received 29 April 1996; manuscript accepted 2 May 1996. Address correspondence to Dr. L.S. Newman, National Jewish Center for Immunology and Respiratory Medicine, 1400 Jackson Street, Room D-104, Denver, CO 80206. Telephone: (303) 398-1725. Fax: (303) 398-1851. E-mail: newmanl@njc.org

18. The Inside Story Beryllium Disease beryllium disease Page 1 2 3 In 1987, Brush set out to combat the two decadesof very damaging literature documenting the dangers of beryllium disease. http://www.chemicalindustryarchives.org/dirtysecrets/beryllium/2.asp

19. Beryllium Facts Information from the manufacturer Brush Wellman about beryllium, chronic beryllium disease, and what is being done about it. http://www.befacts.com/

For 78 years the men and women of Brush Wellman have worked to build a company known throughout the world for the value and quality of its products. In recent months we have seen our good name and reputation attacked by reckless reporting about beryllium (one of our products) which alleges we have lost our commitment to value, ignored our promise of quality and have simply stopped caring about our people. That simply is not true, but we know that one erroneous report will inevitably lead to others, particularly if a source of accurate information is not readily available. This web site is provided as a comprehensive source of information about beryllium, chronic beryllium disease, and what Brush Wellman and others have done and are doing about it. We hope the information is helpful and we encourage you to contact us with any comments, or if you have questions that are not addressed here.

20. Beryllium Support Group Support group for chronic beryllium disease.Category Health Occupational Health and Safety Beryllium...... NABER is an extension of the Colorado, Ohio and Tennessee BerylliumDisease Support Groups. What is beryllium disease (Berylliosis)? http://www.dimensional.com/~mhj/

B eryllium S upport G roup Home Overview Contact Announcements ... Search Overview This web site was formally launched on March 12, 1996 by Michael Jackson a member of the Beryllium Support Group which meets monthly at the National Jewish Medical and Research Center in Denver, Colorado. The intent is to provide a platform where any other Beryllium Support Group regardless of affiliation or location can freely participate in the presentation of or transfer of information relating to this incurable disease. Some of the goals of this site is to provide a means: To provide a forum where anyone around the country or the world can obtain information or provide information they have experienced as a result of this disease. To provide current and historical information on studies and papers relating to this disease. To provide current and historical information relating to the health risks of using beryllium. To provide current and historical information relating to regulations governing the use and control of beryllium. To provide current and historical information of the nature of this disease and its effects on the human body.

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