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         Beryllium Disease:     more detail
  1. Chronic beryllium disease and sensitization at a beryllium processing facility.(Research/ Environmental Medicine): An article from: Environmental Health Perspectives by Kenneth Rosenman, Vicki Hertzberg, et all 2005-10-01
  2. Beryllium Disease: A Summary of the Occupational Health Concern by Renzo Bertolini, 1989
  3. ANALYSES OF FACTORS IN BERYLLIUM ASSOCIATED DISEASES by M.D. John F. Zielinski, 1962
  4. Managing Health Effects of Beryllium Exposure by Committee on Beryllium Alloy Exposures, Committee on Toxicology, et all 2008-09-30
  5. Report on the beryllium problem: As discussed at the sixth Saranac Symposium, Saranac Lake, N.Y., 27 September to 3 October, 1947 by W. E Park, 1947
  6. Beryllium toxicity (Case studies in environmental medicine) by Dennis M Green, 1997

81. Disease
beryllium disease prevention program, Technical info. United States. Berylliumdisease prevention at LLNL, Technical info. United States.
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URL: in English [ Translate Cost to advertiser: Beryllium disease prevention program Technical info. United States Information about the effect of Beryllium on humans, derived from Communicating Beryllium Health Risks Training Materials workshop
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    Beryllium disease prevention program
    Information about the effect of Beryllium on humans, derived from Communicating Beryllium Health Risks Training Materials workshop
    URL: http://tis.eh.doe.gov/be/

82. Beryllium : Meddie Health Search
(Rating 0.00 Votes 0) Rate It. beryllium disease Prevention Program Resources,program information and FAQ's from Lawrence Livermore National Laboratory.
http://www.meddie.com/search/Health/Occupational_Health_and_Safety/Hazardous_Sub
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83. Department Of Energy - News Release
and the general public to provide advice and guidance on a new departmental initiativeto improve worker protection and prevent chronic beryllium disease.
http://www.ch.doe.gov/news/press/pr98182.htm
FOR IMMEDIATE RELEASE
December 3, 1998
NEWS MEDIA CONTACT:
Jeff Sherwood or Jacqueline Johnson, 202/586-5806
Secretary Richardson Asks Public For Input On Initiative to Protect DOE Workers From Lung Disease
Argonne and Fermilab Workers Involved in Illinois
New Proposed Rule Open for Public Comment
Secretary of Energy Bill Richardson today asked the nation's experts in worker and public health to join with current and former Department of Energy (DOE) workers and the general public to provide advice and guidance on a new departmental initiative to improve worker protection and prevent chronic beryllium disease. The proposed rule establishing the initiative was published in today's Federal Register. "The Department of Energy has a clear responsibility to protect workers from disease associated with their work at our sites," said Secretary of Energy Bill Richardson. "Our goal for this new initiative is to prevent future cases of lung disease associated with beryllium and to address the health needs of those who have already been exposed to beryllium. And we want to know what the public, health experts and DOE workers think about this new proposal before putting it into effect." The proposed rule is intended to replace and enhance the interim chronic beryllium disease prevention program issued in a July 1997-DOE Notice. Specific objectives of the new program are to:

84. Policy Analysis And Clinical Research On Occupational Beryllium Exposure At DOE
Adoption of this standard has effectively eliminated the presence of acuteberyllium disease. Laboratory Research on Chronic beryllium disease.
http://www.cresp.org/dcwrkshp/posters/be/be.html
Consortium for Risk Evaluation with Stakeholder Participation
Policy Analysis and Clinical Research on Occupational Beryllium Exposure at DOE Sites
R A Ponce
T K Takaro
S M Bartell
A J Jabbour
K Ertell
J Abbotts
S Barnhart
and E M Faustman
Worker Safety and CRESP and School of Public Health and Community Medicine, University of Washington, Seattle, WA
This research supported in part by CRESP through the Department of Energy Cooperative Agreement #DE-FC01-95EW55084. This support does not constitute endorsement of views expressed.
Introduction
The US Department of Energy has used beryllium in nuclear materials production, reactor rod fabrication, nuclear vessel cladding and many other uses since the 1940s. The industrial use of beryllium was found to result in an acute respiratory disease, acute beryllium disease, leading the Atomic Energy Commission to establish an airborne concentration standard of 2 µg/m3 for the workplace based on then accepted standards for other metals. Adoption of this standard has effectively eliminated the presence of acute beryllium disease. However, epidemiologic studies carried out during the 1980-90s has revealed the presence of another form of lung disease, chronic beryllium disease (CBD), among workers at US DOE sites. In 1997, the Consortium for Risk Evaluation with Stakeholder Participation (CRESP) began a series of research efforts to investigate the prevalence of CBD among former beryllium workers at Hanford, evaluation of alternatives to the current screening tools for identifying pre-clinical disease, and policy implications of alternative occupational health program designs to reduce disease incidence among future beryllium workers, such as those involved in decontamination and decommissioning former beryllium facilities.

85. Beryllium Handling And Exposure
Inhalation of high concentrations of beryllium in air is associated with acute berylliumdisease. Fatigue. · Fevers. Chronic beryllium disease is treatable.
http://www.jlab.org/ehs/manual/EHSbook-570.html
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Beryllium Handling and Exposure
[6682 Beryllium Handling and Exposure - Rev. November 16, 2001 ]
Introduction
Beryllium is used at the Laboratory in alloys and in pure and ceramic form for targets and various beamline components. Beryllium can also be found in electronic devices such as rectifiers. The materials containing beryllium at Jefferson Lab are considered to be "articles" (see key terms in this chapter), which should present no hazards under normal handling conditions. This is because handling of solid components does not normally result in measurable airborne beryllium particulate. This chapter contains the information necessary to limit employee exposure to beryllium, with special emphasis on preventing exposure to beryllium associated with non-routine conditions involving beryllium articles.
Jefferson Lab beryllium inventory
Health Effects
Health effects associated with beryllium exposure can manifest in two ways: direct damage caused by the chemical toxicity of beryllium, and allergic reaction caused by the effect of beryllium on the immune system. Not all individuals overexposed to beryllium will suffer the allergic reaction; however those that do may have a delay of several years before the allergic reaction manifests.
Direct Chemical Toxic Effects
Beryllium contact with the skin is associated with ulcer formation. Inhalation of high concentrations of beryllium in air is associated with acute beryllium disease. Acute beryllium disease can cause chemical pneumonitis, similar to bronchitis or pneumonia. This acute disease is very rare, because of increased awareness/housekeeping programs now required in manufacturing.

86. Augusta Georgia: Technology:New Lab Will Test For Beryllium Disease 01/22/02
OAK RIDGE, Tenn. Thousands of workers will be tested annually for beryllium diseaseat a new Oak Ridge laboratory. New lab will test for beryllium disease.
http://www.augustachronicle.com/stories/012202/tec_124-4417.shtml

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By Frank Munger
Scripps Howard News Service OAK RIDGE, Tenn. - Thousands of workers will be tested annually for beryllium disease at a new Oak Ridge laboratory. Chronic beryllium disease is an incurable, sometimes fatal respiratory illness caused by exposure to beryllium, a lightweight metal used historically in the production of warhead parts at the Y-12 nuclear weapons plant in Oak Ridge. "This may be small space, but it's a mighty space to workers in Oak Ridge," said Leah Dever, the Department of Energy's Oak Ridge manager. The new lab will be used to analyze blood samples to determine if a worker's body has become "sensitized" to beryllium. That's the first stage in development of beryllium disease. Based on tests conducted since 1992, 114 past or present workers at Y-12 were found to be sensitized to beryllium. There have been 44 documented cases of chronic beryllium disease among workers at the warhead production facility. Those workers or their survivors are eligible for a special compensation program passed by Congress that provides up to $150,000 and medical benefits. The new test lab will receive blood samples from Y-12 and workers at more than a dozen other DOE facilities around the United States.

87. News Update 8/2/01
beryllium disease in Private Industry on the Rise. beryllium disease is caused byberyllium dust, which damages lungs. It is a rare and often fatal condition.
http://www.nuclearactive.org/news/080201.html

Beryllium Disease in Private Industry on the Rise

Senator Harry Reid of Nevada Joins Nuclear Regulatory Commission

The Chicago Tribune reported this week that thousands of American workers are at risk of contracting beryllium disease because of poor working conditions in the dental, machining and electronics industries, among others. The federal Occupational Safety and Health Administration (or OSHA) has placed warnings on beryllium and established limits to beryllium exposure. OSHA requirements also state that there must be regular air monitoring for beryllium, and medical testing must be available to any worker who is exposed. However, neither the businesses handling beryllium nor OSHA are enforcing the measures. Beryllium was once primarily used in the production of nuclear weapons. Private industry now uses beryllium because of its light weight and strength. Beryllium disease is caused by beryllium dust, which damages lungs. It is a rare and often fatal condition. Scientists predict that up to 16% of those exposed to beryllium dust will contract the disease. A check of 30 businesses using beryllium found that none were following all of OSHA's recommendations, four failed to mention the threat of beryllium disease to its employees, and that some Chicago area businesses had not been inspected by OSHA in a decade. It is estimated that at least 2,000 workers have been exposed to beryllium dust without warning or precautions since 1970.

88. ADA News: OSHA Issues Beryllium Bulletin For Dental Labs
OSHA cited several reports of chronic beryllium disease, a debilitatingand often fatal lung disease, among dental technicians.
http://www.ada.org/prof/pubs/daily/0204/0423osha.html
Publications ADA News Today Past News Departments ... Contact ADA Publishing ADA News Posted April 24, 2002
OSHA issues beryllium bulletin for dental labs By Craig Palmer Washington Today's stories War on terrorism Dental readiness Dr. Austin HIPAA complaints The unusual nationwide warning in the form of a Hazard Information Bulletin, the first warning of its type this year, is posted online at the OSHA Web site . OSHA said such warnings are intended to provide information about occupational hazards but are neither standards nor regulations, "and they create no independent legal obligation. They are advisory in nature, informational in content, and are intended to assist employers in providing a safe and healthful workplace." OSHA cited several reports of chronic beryllium disease, a debilitating and often fatal lung disease, among dental technicians. The Hazard Information Bulletin applies to dental labs and not to dental offices unless beryllium-containing dental alloys are fabricated or modified in dental offices, the agency said. The advisory is entitled, "Preventing Adverse Health Effects from Exposure to Beryllium in Dental Laboratories."

89. CROET: Beryllium Health And Safety Resources
0222.pdf. Chronic beryllium disease Prevention Program http//tis.eh.doe.gov/be/index.htmlssi(US Department of Energy). Toxic Beryllium
http://www.ohsu.edu/croet/exposure/beryllium.html
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Please select About this site Link to us Suggest a link Linking criteria Beryllium is a brittle, steel-grey metal found as a component of coal, oil, certain rock minerals, volcanic dust, and soil. It causes lung and skin disease in 2% to 10% of exposed workers. Occupational exposure most often occurs in mining, extraction, and in the processing of alloy metals containing beryllium. The adverse health effects of beryllium exposure are caused by the body's immune system reacting with the metal, resulting in an allergic-type response. Dust control is the primary preventative measure. OSHA, http://www.osha.gov/SLTC/beryllium/
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90. 1Up Health > Health Links Directory > Occupational Health And Safety: Hazardous
exposure. beryllium disease Prevention Program Resources, program informationand FAQs from Lawrence Livermore National Laboratory.
http://www.1uphealth.com/links/hazardous-substances-beryllium.html
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... Hazardous Substances : Beryllium
See Related Categories Science: Chemistry: Elements: Beryllium
Sites Communicating Health Risks: Working Safely with Beryllium
OSHA Safety and Health, OSHA Hazard Information Bulletins: Preventing Adverse Health Effects From Exposure to Beryllium on the Job. American Metal Market - Beryllium Profile Metal Statistics '99 beryllium profile at AMM.com. This is an international daily news service covering the metals and recycling industries. ARC Anticipated Carcinogens:Beryllium and Certain Berryllium Compounds Information and fact sheet from the National Institute of Health. Beryllium Beryllium is a toxic substance that can be harmful, depending on the amount and duration of exposure. (U.S. Department of Energy Office of Environment, Safety and Health) Beryllium and Compounds U.S. Environmental Protection Agency fact sheet on hazards from beryllium exposure.

91. Project Aims
cause three types of disease. These are beryllium sensitization, chronicberyllium disease (CBD), and acute beryllium disease (ABD).
http://dcc2.bumc.bu.edu/Nevada/beryllium.htm
Beryllium Beryllium metal was ground, machined, and modified in a variety of settings at the Nevada Test Site. Beginning in March 2001, we began offering the beryllium lymphocyte proliferation test (BeLPT) to eligible former workers attending our screening. Beginning in June 2001, we plan to notify and invite former screening participants believed to be exposed to beryllium to take the BeLPT. Beryllium dust and oxides can cause three types of disease. These are beryllium sensitization, chronic beryllium disease (CBD), and acute beryllium disease (ABD). Beryllium sensitization is an allergic reaction to beryllium metal. People with beryllium sensitization do not show any signs of disease. However, because people with beryllium sensitization are sensitive to beryllium, they are at risk for developing a much more serious illness called chronic beryllium disease. Chronic beryllium disease (CBD) , or berylliosis , is a scarring disease of the lungs. Symptoms can include dry cough, shortness of breath, tiredness, chest and joint pain, rapid heart rate, loss of appetite, fever, and night sweats. CBD can develop anytime from a few months to 40 years after a person’s first exposure to beryllium. Acute beryllium disease (ABD) occurs immediately after a high exposure to beryllium. Since the 1950’s there have been very few cases of ABD due to improved industrial practices.

92. Beryllium Disease, "A Disaster Waiting To Happen," Chicago Tribune Investigation
smallRW.gif (2706 bytes), beryllium disease, A Disaster Waiting ToHappen, Chicago Tribune Investigation. CHICAGO, July 28 /PRNewswire
http://www.riskworld.com/PressRel/2001/01q3/PR01a008.htm
Beryllium Disease, "A Disaster Waiting To Happen," Chicago Tribune Investigation CHICAGO, July 28 / PRNewswire A Chicago Tribune investigation has found that thousands of Americans are at risk for developing a chronic, potentially fatal lung disease because companies have exposed them to the highly toxic metal beryllium without adequate safeguards or warnings. The story by reporter Sam Roe is published in the Sunday, July 29, Chicago Tribune The Tribune investigation, based on thousands of court, industry and government documents and dozens of interviews with health officials and business owners, found: Many businesses are not taking basic precautions, such as air monitoring. In a spot check of 30 businesses across the country working with beryllium, the Tribune found that none were following the safeguards recommended by the Occupational Safety and Health Administration (OSHA). Warnings from beryllium manufacturers and distributors are often inaccurate, misleading and incomplete. Of 10 warnings reviewed by the Tribune, nine failed to abide by OSHA rules and four failed to even mention beryllium disease. OSHA rarely inspects companies that handle beryllium. Several Chicago-area businesses working with the metal have not been inspected in 10 years.

93. Eco-USA: Beryllium
Toxicological profile of beryllium, including information on environmental fate and transport, exposure Category Health Occupational Health and Safety Beryllium...... lungs. This condition is called acute beryllium disease. In this Thiscondition is called chronic beryllium disease. This disease can
http://www.eco-usa.net/toxics/berylium.shtml

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Introduction
Fate and Transport Exposure Pathways ... Health Effects
Introduction
Beryllium
is a hard, grayish element that does not occur naturally. The element does occur as a chemical component of certain rocks, coal and oil, soil, and volcanic dust. Two kinds of mineral rocks, bertrandite and beryl, are mined commercially for the recovery of beryllium. Very pure gem-quality beryl is better known as either aquamarine (blue or blue-green) or emerald (green). Beryllium is also present in a variety of compounds. They do not have any particular smell. There are two types of beryllium compounds, those that dissolve in water and those that do not. Most of the beryllium ore that is mined is converted into alloys (mixtures of metals). Most of these alloys are used in making electrical and electronic parts or as construction materials for machinery and molds for plastics. Pure beryllium metal has applications in nuclear weapons and reactors, aircraft and space vehicle structures and instruments, X-ray machines, and mirrors. Beryllium oxide is also made from beryllium ores and is used to make specialty ceramics for electrical and high-technology applications. Beryllium enters the air, water, and soil as a result of natural and human activities. Emissions from burning coal and oil increase beryllium levels in air. Beryllium enters waterways from the wearing away of rocks and soil. Most of the man-made beryllium that enters waterways comes when industry dumps waste water and when beryllium dust in the air from industrial activities settles over water. Beryllium, as a chemical component, occurs naturally in soil; however, disposal of coal ash, incinerator ash, and industrial wastes may increase the concentration of beryllium in soil.

94. 09/21/00 Committee On The Judiciary - Rosenman Statement
117 West Fee Hall. East Lansing, MI 488241316. Rosenman@msu.edu. 517-353-1846.FAX 517-432-3606. Summary. Chronic beryllium disease primarily affects the lungs.
http://www.house.gov/judiciary/rose0921.htm
Testimony of Kenneth D. Rosenman, M. D. Regarding Bills on Compensation for Beryllium-Related Illness Before the Subcommittee on Immigration and Claims of the Committee on the Judiciary Kenneth D. Rosenman, M. D. Professor of Medicine Michigan State University Department of Medicine 117 West Fee Hall East Lansing, MI 48824-1316 Rosenman@msu.edu FAX: 517-432-3606 Summary Chronic Beryllium Disease primarily affects the lungs. It is a progressive, potentially fatal disease with few treatment options, that may occur years after beryllium exposure has ended. Among 1,370 individuals tested at two beryllium extraction facilities in Eastern Pennsylvania, 72 (5.3%) people were diagnosed with Chronic Beryllium Disease and 73 (5.3%) were diagnosed with sensitization. Pennsylvania Workers’ Compensation Law precludes filing a workers’ compensation claim more than five years after cessation of exposure. Most individuals we have diagnosed with Chronic Beryllium Disease or sensitization have been precluded from filing by this statute of limitation. Some have been denied medical coverage by their existing health insurance plan because they have a work-related disease. Accordingly, they have been left to fend for themselves to pay their medical bills. Thank you for the invitation to speak today before the Subcommittee on Immigration and Claims of the Committee on the Judiciary.

95. Beryllium Network: Beryllium Dangers To Workers And Their Families
Information about berylliumrelated diseases and legal options, from a California law firm.
http://www.chronicberylliumdisease.com/
But the miracle element has disastrous effects. Exposure to beryllium in the workplace may lead to various diseases including chronic beryllium disease , which causes a painful scarring of the lung tissue. Workers in certain occupations and industries medical issues exposure risks recent news ... medical centers and support groups glossary of medical terms to assist you in navigating through the intricacies of the medical system.
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March 21, 2003
Workers at Uranium Enrichment Plant Exposed to Beryllium
December 6, 2002
OSHA to Revisit Effects of Beryllium Exposure
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96. The Natural History Of Beryllium Sensitization And Chronic Beryllium Disease
The Natural History of beryllium Sensitization and Chronic berylliumDisease. Lee S. Newman, 1,2 Jenifer Lloyd, 1 and Elaine Daniloff 1.
http://ehpnet1.niehs.nih.gov/docs/1996/Suppl-5/newmanabs.html
Conference on Beryllium-related Diseases
Environmental Health Perspectives 104, Supplement 5, October 1996 Citation in PubMed Related Articles
The Natural History of Beryllium Sensitization and Chronic Beryllium Disease
Lee S. Newman, Jenifer Lloyd, and Elaine Daniloff Departmet of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado; Department of Medicine and Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado
Abstract
Environ Health Perspect 104(Suppl 5):937-943 (1996) Key words: beryllium, chronic beryllium disease, granuloma, cell-mediated immunity, lymphocyte, natural history, lung disease, pulmonary, immunology, metal toxicity This paper was presented at the Conference on Beryllium-related Diseases held 8-10 November 1994 in the Research Triangle Park, North Carolina. Manuscript received 29 April 1996; manuscript accepted 1 May 1996. Address correspondence to Dr. S. Newman, National Jewish Center for Immunology and Respiratory Medicine, 1400 Jackson Street, Room D-104, Denver, CO 80206. Telephone: (303) 398-1725. Fax: (303) 398-1851. E-mail: newmanl@njc.org

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