21. Biomerica, Inc.: EZ-HP, One-Step Helicobacter Pylori Test In 1983, Helicobacter pylori (previously known as campylobacter pylori) was foundin close contact with gastric epithelium in biopsy samples showing active http://biomerica.com/html/ezhp.html

home the company financial info news/press ... contact us EZ-HP One-Step Helicobacter pylori Test Detection of IgG Antibodies to H.pylori in Whole Blood Overview Summary and Explanation Principle of the Test Materials Provided ... References Overview Simple Flexible Sensitive Quick Reliable Saves time, money Summary and Explanation In 1983, Helicobacter pylori (previously known as Campylobacter pylori) was found in close contact with gastric epithelium in biopsy samples showing active type B or chronic gastritis (6,7,8,9,10). Although the source of H. pylori infection is unknown, reports (3,12,14) have shown quite convincingly that H. pylori infection can be associated with chronic gastritis. A positive correlation has been found between the presence of H. pylori and gastric lesions in some cases of duodenal ulcers (15,16). Complete resolution of gastritis after eradication of the organism has also been reported (17,18). H. pylori is a gram negative, curved, spiral shaped rod bacteria (0.2 - 0.8 µm in width by 0.5 - 5.0 µm in length). H. pylori colonization is found in the deep portions of the mucous layer that coats the gastric mucosa, and between the mucous layer and apical surface of the gastric mucosal epithelial cells in some infected patients (1). H. pylori may also be located in the regions of junctions between adjacent mucosal epithelial cells. It produces three enzymes in large amounts; urease, superoxide dismutase and catalases (14,17,18). Urease splits urea to produce ammonia, which provides the conditions needed for the multiplication and sustenance of the organism in the gastric environment. Colonization may induce the host's local and systemic immune response, and may cause clinical signs and symptoms including neutrophilic infiltration and the production of specific antibodies.

22. Swiss-Prot Release 41.2 Statistics Schizaphis graminum) 34 536 Helicobacter pylori (campylobacter pylori) 35 535 Rickettsiaprowazekii 36 519 Helicobacter pylori J99 (campylobacter pylori J99 http://us.expasy.org/sprot/relnotes/relstat.html

ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ... Hosted by NCSC US Mirror sites: Canada China Korea Switzerland ... Taiwan Search Swiss-Prot/TrEMBL Swiss-Prot/TrEMBL (full text) PROSITE SWISS-2DPAGE ENZYME NEWT Taxonomy HAMAP families ExPASy web site for SWISS-PROT PROTEIN KNOWLEDGEBASE RELEASE 41.2 STATISTICS 1. INTRODUCTION Release 41.2 of 28-Mar-2003 of Swiss-Prot contains 123721 sequence entries, comprising 45421741 amino acids abstracted from 104046 references. 1160 sequences have been added since release 41, the sequence data of 89 existing entries has been updated and the annotations of 5076 entries have been revised. This represents an increase of 1%. The growth of the database is summarized below. 2. AMINO ACID COMPOSITION 2.1 Composition in percent for the complete database Ala (A) 7.72 Gln (Q) 3.92 Leu (L) 9.56 Ser (S) 6.98 Arg (R) 5.24 Glu (E) 6.54 Lys (K) 5.96 Thr (T) 5.51 Asn (N) 4.28 Gly (G) 6.90 Met (M) 2.36 Trp (W) 1.18 Asp (D) 5.28 His (H) 2.26 Phe (F) 4.06 Tyr (Y) 3.12 Cys (C) 1.59 Ile (I) 5.88 Pro (P) 4.87 Val (V) 6.66 Asx (B) 0.000 Glx (Z) 0.000 Xaa (X) 0.01 3.3 Taxonomic distribution of the sequences

23. HELPY Helicobacter pylori (campylobacter pylori). Species Helicobacter pylori(campylobacter pylori). Species code HELPY. Type Eubacteria. http://us.expasy.org/sprot/hamap/HELPY.html

ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot ... Hosted by NCSC US Mirror sites: Canada China Korea Switzerland ... Taiwan Search Swiss-Prot/TrEMBL Swiss-Prot/TrEMBL (full text) PROSITE SWISS-2DPAGE ENZYME NEWT Taxonomy HAMAP families ExPASy web site for Helicobacter pylori (Campylobacter pylori) H IGH-QUALITY A UTOMATED AND M ANUAL A NNOTATION OF MICROBIAL P ROTEOMES HAMAP home HAMAP proteomes ... FTP server Species: Helicobacter pylori (Campylobacter pylori) Species code: HELPY Type: Eubacteria Taxonomy: Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter (TaxID: 210) [ NEWT NCBI Strain(s): 26695 / ATCC 700392 Genome: circular, 1.67 Mb; no ECE Reference(s): MEDLINE=97394467 [ NCBI ExPASy Israel Japan ]; PubMed= Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S., Dougherty B.A., Nelson K., Quackenbush J., Zhou L., Kirkness E.F., Peterson S., Loftus B., Richardson D., Dodson R., Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.M., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.; "The complete genome sequence of the gastric pathogen Helicobacter pylori.";

24. Biographies Of Members - Michel A. L. Deltenre Nyst JF, Burette A, Labbé M, Jonas C, De Koster E. The reliability of urease tests,histology, and culture in the diagnosis of campylobacter pylori Infection. http://www.helicobacter.org/ehpsg_biographies_Deltenre.htm

European Helicobacter Study Group Biographies of Members CURRICULUM VITÆ Professor Michel-A-L DELTENRE Head of the Clinic of Hepato-Gastroenterology and manager of Internal Medicine Department University Hospital Brugmann (Free University Brussels ULB-VUB). Place Van Gehuchten 4 B 1020 Brussels Teaching (Faculty of Medicine-Free University Brussels) GI clinics for graduates Health Certification, Internal Medicine and Gastroenterology Special License Imagining and Endoscopy INEA (Nursing Institute) Visiting Professor: Washington University GI unit Prof. CE RUBIN 1977. Chairman ENDO 90 XXIV th International Congress of the SMIER. Brussels 1990. Chairman VI th Workshop on Gastroduodenal Pathology and Helicobacter pylori . Brussels 1993. Past president of Belgian society for Digestive Endoscopy Past president and founder of the Belgian H. pylori group. Fields of Interest Pancreatic diseases, Operative Endoscopy, GERD Publications in H. pylori field Deltenre M, Glupczynski Y, DePrez C, Nyst JF, Burette A, Labbé M, Jonas C, De Koster E. The reliability of urease tests, histology, and culture in the diagnosis of Campylobacter pylori Infection. 1989. Scand J Gastroenterol S 160: 19-24.

25. Ehpsg - Biographies Of Members - Leif Percival Andersen Scandinavian Journal of Gastroenterology 1987, 22, 219 224. 3. Andersen, LP,Elsborg, L., Justesen, T. campylobacter pylori in peptic ulcer disease 111. http://www.helicobacter.org/ehpsg_biographies_l_p_andersen.htm

European Helicobacter Study Group Biographies of Members CURRICULUM VITÆ Leif Percival Andersen Dept. of Clinical Microbiology 7806 National University Hospitai (Rigshospitalet) Tagensvej 20, DK-2200 Copenhagen N, Denmark phone +45 3545 7784, fax +45 3545 6831 E-mail Ipa@biobase.dk Pubmed Publications List Current position Staff Doctor Dept. of Clinical Microbiology National University Hospital (Rigshospitalet) Copenhagen, Denmark Education Danish Authorization as a Physician (University of Copenhagen) Full Registration as a Physician Specialist in Clinical and Medical Microbiology Profesional experience Second Lieutenant, Royal Danish Navy Resident Infectious Diseases, Rigshospitalet, Copenhagen 1986 - 88 Resident Virology, Statens Serum Institut, Copenhagen Resident Infectious Diseases, Rigshospitalet Staff Doctor Clinical Microbiology, Rigshospitalet Hoechst, Denmark AntibioticAward Twenty Centery Award of Achievement International Man of the Year Since 1994 In international bibliographies Who's Who in the World Who's Who in Dictionary of International Biography Five Hundred Leaders of Influence Since 1994 Reviewer for APMIS, Infection and Immunity, European Journal of

26. I Helicobacter Pylori /i Culture (180885) 87081; 87205 Related Information Helicobacterpylori, IgG. Synonyms CampylobacterFrom Stomach; campylobacter pylori; Culture, Helicobacter pylori Test Includes http://www.labcorp.com/datasets/labcorp/html/chapter/mono/mb020900.htm

Culture (180885) Helicobacter pylori Culture (180885) CPT Related Information Helicobacter pylori , IgG Synonyms Campylobacter From Stomach; Campylobacter pylori ; Culture, Helicobacter pylori Test Includes Culture; smear for modified Gram's stain (reported only if positive and culture does not grow); isolation and identification (additional charges/CPT code[s] may apply). CPT coding for microbiology and virology procedures often cannot be determined before the culture is performed. Specimen Gastric material Volume Biopsy Container Anaerobic transport, aerobic-anaerobic bacterial swab transport system, CLO vial, urea agar medium Storage Instructions Maintain specimen at room temperature. Causes for Rejection Inappropriate specimen transport device; mislabeled specimen; unlabeled specimen; specimen received after prolonged delay (usually more than 72 hours) Use Establish the presence and possible etiologic role of Helicobacter pylori in cases of chronic gastric ulcer, gastritis, duodenal ulcer, dyspepsia, etc Methodology Culture Additional Information Helicobacter pylori has been implicated as a factor associated with chronic gastritis. The clinical significance of the organism in regard to gastric or duodenal ulcers, dyspepsia, and gastric carcinoma remains unclear.

27. Published Articles On Helicobacter Pylori( CGC) Prevalence of campylobacter pylori in Normal Korean Person. campylobacter pylorias a Major Determinant in Hypothetical Carcinogenesis of Stomach Cancer. http://kid.gsnu.ac.kr/gastritis/helico1.html

Site for Published Articles on Helicobacter pylori (with English abstract) Prevalence of Campylobacter pylori in Normal Korean Person Campylobacter pylori ... E-mail

28. Published Articles On Helicobacter Pylori( CGC) 24269279, 1989 Antimicrobial Susceptibility of campylobacter pylori Isolates fromGastric Mucosa of Koreans kwang-Ho Rhee, Myung-Je Cho, Gyeong-Hee Kang, Woo http://kid.gsnu.ac.kr/gastritis/g5.html

Source : J. Korean Soc. Microbiol. 24:269-279, 1989 Antimicrobial Susceptibility of Campylobacter pylori Isolates from Gastric Mucosa of Koreans kwang-Ho Rhee, Myung-Je Cho, Gyeong-Hee Kang, Woo-Kon Lee, Hang-Hi Ryou and Jong-Bae Kim Department of Microbiology, College of Medicine, Gyeong-Sang National University, Chinju, Kyung-Nam 660-280, Korea Department of Medical Technology, college of Health Science, Yonsei University, Wonju, 220-050, Korea The in vitro susceptibility with a total of 97 isolates of Campylobacter pylori 62.4§¶/ml). Key words : Campylobacter pylori , Antimicrobial susceptibility

29. References: H. Pylori campylobacter pylori and its role in peptic ulcer disease. Stolte M, Eidt S. Lymphoidfollicles in antral mucosa immune response to campylobacter pylori. http://webcampus.med.drexel.edu/cme/medicine/h-pylori/referenc.htm

Monograph Home Introduction Historical Perspectives The Bacteria ... Evaluation REFERENCES Bizzozero B. Beziehunger ihres Epithel za dem Oberfachenepithel der Schleimhart. Arch f Mikr Anat 23:82-152, 1893. Palme r ED. Investigation of the gastric mucosa spirochetes of the human. Gastroenterology 27:218-220, 1954. Steer HW, Colin-Jones DG. Mucosal changes in gastric ulceration and their response to carbenoxolone sodium. Gut 16:590-597, 1975. Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ. Attempt to fulfil Koch's postulates for pyloric Campylobacter. Med J Aust 142:436-439, 1985. Morris A, Nicholson G. Ingestion of Campylobacter pyloridis causes gastritis and raised fasting pH. Am J Gastroetnerol 82:191-199, 1987. Handt LK, Fox JG, Stalis IH, Rufo R, Lee T, Linn J, LiX, Kleanthous H. Characterization of feline Helicobacter pylori strains and associated gastritisi in a colony of domestic cats. J Clin Microbiol 33:2280-2289, 1995. Cave DR. How is Helicobacter pylori transmitted? Gastroenterology 113:S9-S14, 1997.

30. Medmicro Chapter 23 Helicobacter pylori (formerly known as campylobacter pylori), which was firstcultured from gastric biopsy tissues in 1982, causes chronic superficial http://gsbs.utmb.edu/microbook/ch023.htm

Campylobacter and Helicobacter Guillermo I. Perez-Perez Martin J. Blaser General Concepts Campylobacter Jejuni and other Enteric Campylobacters Clinical Manifestations Campylobacter species cause acute gastroenteritis with diarrhea, abdominal pain, fever, nausea, and vomiting. Recently, Campylobacter infections have been identified as the most common antecedent to an acute neurological disease, the Guillain-Barré syndrome. Structure Campylobacter species are Gram-negative, microaerophilic, non-fermenting, motile rods with a single polar flagellum; they are oxidase-positive and grow optimally at 37° or 42°C. Classification and Antigenic Types Campylobacter species have many serogroups, based on lipopolysaccharide (O) and protein (H) antigens. However, only a few serogroups account for most human isolates in a given geographic region. C jejuni possesses several common surface-exposed antigens, including porin protein and flagellin. Pathogenesis The bacteria colonize the small and large intestines, causing inflammatory diarrhea with fever. Stools contain leukocytes and blood. The role of toxins in pathogenesis is unclear. C jejuni antigens that cross-react with one or more neural structures may be responsible for triggering the Guillian-Barre syndrome.

31. Haemophilus Influenzae B Antibody, IgG Clinical Significance Previously known as campylobacter pylori, Helicobacterpylori is a gramnegative, curved, spiral-shaped, urease-positive http://www.aruplab.com/guides/clt/tests/clt_a249.htm

ARUP's Guide to Clinical Laboratory Testing (CLT) A B C D ... Search Note: Test code links throughout this Guide refer to the corresponding test in the User's Guide. Haemophilus influenzae b Antibody, IgG Test Number: Methodology: Multi-Analyte Fluorescent Detection Clinical Significance Haemophilus influenzae was the most common cause of bacterial meningitis in infants and children until an effective conjugated vaccine was developed and utilized. Serum antibodies to the H. influenzae type-b polysaccharide are protective against invasive disease. The high morbidity associated with this organism, as well as the availability of a vaccine, makes this an ideal test to assess the production of antibody against a protein-polysaccharide conjugate vaccine. This antibody is contained mainly within the IgG 1 subclass. Reference Interval: H. influenzae b detected. Suggestive of protection. Responder status is determined according to the ratio of post-vaccination concentration to pre-vaccination concentration of Haemophilus influenzae b antibody, IgG as follows:

32. Helicobacter Pylori IgG And IgA campylobacter pylori detected noninvasively by the 13Curea breath test.Lancet 1987; 11174-1177. campylobacter pylori antibodies in humans. http://www.aruplab.com/testbltn/helicobacter.htm

Helicobacter pylori IgG and IgA Confirmation by Western blot Analysis For technical information, contact: Nancy Pitstick, B.S., MT(ASCP) Technical Supervisor, Microbial Immunology I For scientific and clinical information, contact: Harry R. Hill, M.D. Medical Director, Immunology Laboratory Christine Litwin, M.D. Medical Director, Immunology Laboratory References: Warren JR and Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983; 1:1273-1275. Blaser MJ. Gastric Campylobacter-like organisms, gastritis, and peptic ulcer disease. Gastroenterology 1987; 93:371-383. Graham DY, et al. Campylobacter pylori detected noninvasively by the 13C-urea breath test. Lancet 1987; 1:1174-1177. Perez-Perez GI, et al. Campylobacter pylori antibodies in humans. Ann Intern Med 1988; 109:11-17. Vaira D, et al. Antibody titers to Campylobacter pylori after treatment for gastritis. Br Med J 1988; 297(6645):397. Morris AJ, et al. Long-term follow-up of voluntary ingestion of Helicobacter pylori . Ann Int Med 1991; 114:662-663.

33. Campylobacter Links- FoodHACCP.com Briefings Campylobacter Chronic Fowl Hazards Estimated Food Poisoning fromCampylobacter and CSPI Gastroenterology campylobacter pylori Genomic tRNA http://www.foodhaccp.com/campylobacter.html

Campylobacter AID - Immunoblots Campylobacter jejuni Campy.jejun ... Campylobacter jejuni tmRNA: CAMPYLOBACTER Campylobacter Campylobacter Campylobacter - Arizona.edu Campylobacter enteritis in humans Campylobacter enteritis- Overview Campylobacter FAQ page Campylobacter in the news ... Campylobacter info ... Campylobacter Infections. WHAT IS CAMPYLOBACTER Campylobacter jejuni Campylobacter jejuni Campylobacter jejuni (Family Practice Notebook.com) Campylobacter jejuni Campylobacter jejuni genome website Campylobacter jejuni -NCSU.edu Campylobacter jejuni organism Campylobacter Questions and Answers Campylobacter UK 2000 meeting Campylobacter Washington University CAMPYLOBACTER ... Back to disease index CAMPYLOBACTER Overseas information: Campylobacter: Low-Profile Bug Is Food Poisoning Leader Campylobacter: No longer the 'quiet' pathogen Campylobacteriosis CAMPYLOBACTERIOSIS (Campylobacter) ... DBMD - Campylobacter Infections - General Information -CDC Information Developments in the Campylobacter Program - FSIS Information DIARRHEA ... CAMPYLOBACTER ENTERITIS Quick Facts available Differentiation of Campylobacter coli and C. jejuni by length

34. Entry Page ID 209 RANK species GC ID 11 SCIENTIFIC NAME Helicobacter pylori SYNONYM Helicobacter nemestrinae SYNONYM campylobacter pylori Marshall et al. http://ben.vub.ac.be/srs6bin/wgetz?-id 3Dfbj1KZajC -e [TAXONOMY:'210']

35. Entry Page tt; Y895_HAEIN HYPOTHETICAL PROTEIN HI0895 HAEMOPHILUS INFLUENZAE. tt;O68962 RND PUMP PROTEIN - HELICOBACTER PYLORI (campylobacter pylori). http://ben.vub.ac.be/srs6bin/wgetz?-id 3Dfbj1KZakh -e [PRINTS:'ACRIFLAVINRP']

36. Role Of Helicobacter Pylori In The Genesis Of Gastric Ulcerations Among Smokers Translate this page pylori, formerly known as campylobacter pylori, are Gram-negative microaerophilicspiral bacteria that have been identified by culture only in the past decade http://www.emro.who.int/Publications/EMHJ/0302/16.htm

Role of Helicobacter pylori in the genesis of gastric ulcerations among smokers and nonsmokers Volume 3, Issue 2, 1997, Page 316-321 M.A. El-Barrawy, M.I. Morad and M. Gaber ABSTRACT Helicobacter pylori infection was investigated by three different methods (serologically, microbiologically and biochemically) in 210 male patients aged 20-40 years. Gastric ulcers were diagnosed in 126 patients in which H. pylori infection showed a significant association (c = 162.8). Smokers had a higher rate of infection than nonsmokers, both among patients with gastric ulcers (99% compared to 79%) and without. The risk of H. pylori infection was computed for different categories of smoker. Heavy cigarette smokers were found to have the highest risk, followed by moderate to mild cigarette smokers and communal shisha smokers; neither private shisha nor cigar/pipe smokers showed any significant risk. Rôle d' Helicobacter pylori dans la genèse des ulcérations gastriques chez les fumeurs et les non-fumeurs. RESUME L'infection par Helicobacter pylori a fait l'objet d'investigations à l'aide de trois méthodes différentes (sérologique, microbiologique et biochimique) chez 210 patients de sexe masculin âgés de 20 à 40 ans. Des ulcères gastriques ont été diagnostiqués chez 126 patients pour lesquels une association significative avec l'infection par

37. Póster Electrónico Nº 029 BIBLIOGRAFÍA Paull A. y col. Gastric and esophageal campylobacter pylori in patients withBarrett´s esophagus Gastroenterology 1988; 95216-218. Talley y col. http://www.conganat.org/iicongreso/posters/029/biblio.htm

Póster Nº 029 Indice Organismos Helicobacter pylori en esófago de Barrett; prevalencia en Córdoba, Argentina. Sambuelli, Ruben; Armando, Raúl; Guidi, Andrés; Trakal, Esteban; Butti, Abel; Gómez, Silvia; Trakal, Juan José; De la Vega, Juan; Alarcón, Matías. TITULO INTRODUCCIÓN MATERIAL Y METODOS RESULTADOS ... BIBLIOGRAFÍA BIBLIOGRAFÍA Trakal E. y col. Organismos tipo Campylobacter en esófago de Barret- Act.Gastroenterol. Lat.Am. 1987; 17:85-96 Paull A. y col. Gastric and esophageal Campylobacter pylori in patients with Barrett´s esophagus- Gastroenterology 1988; 95:216-218 Talley y col. Campylobacter pylori colonization of Barrett´s esophagus- Gastroenterology 1988; 94:A454 Talley y col. Campylobacter pylori and Barrett´s esophagus- Mayo Clinic Proc. 1988;63: 1176-1180 Hazell, Z. Campylobacter pylori can infect the oesophagus- Gastroenterology 1988; 94:A178 Grahan, D. Campylobacter pylori and Barrett´s esophagus- Mayo Clinic Proc. 1988; 63:1258-60 Walker y col. Patterns of colonissation of Campylobacter pylori in the esophagus, stomach and duodenum- Gut 1989; 30:1334-1338 Stuart y col. Campylobacter pylori and Barrett´s mucosa, an association of prognostic significance- Gut 1989; A279

38. EMedicine - Campylobacter Infections : Article Excerpt By: Mahmud Javid, MD These organisms are related to Helicobacter pylori, which was previouslyknown as campylobacter pylori. No reservoir other than http://www.emedicine.com/med/byname/campylobacter-infections.htm

(advertisement) Excerpt from Campylobacter Infections Synonyms, Key Words, and Related Terms: diarrhea, dysentery, enteric infection, enteritis, gastroenteritis, campylobacteriosis, Campylobacter jejuni, C jejuni, Campylobacter fetus, C fetus, Campylobacter lari, C lari, Campylobacter upsaliensis, C upsaliensis, Campylobacter hyointestinalis, C hyointestinalis, Campylobacter pylori, C pylori, Helicobacter pylori, H pylori, Helicobacter cinaedi, H cinaedi, Helicobacter fennelliae, H fennelliae, enterocolitis, proctocolitis, bacteremia, acquired immunodeficiency syndrome, AIDS, human immunodeficiency virus, HIV, traveler's diarrhea, toxic megacolon, pseudoappendicitis, inflammatory bowel disease, IBD, Guillain-Barré syndrome Please click here to view the full topic text: Campylobacter Infections Background: Campylobacter infections are among the most common bacterial infections of humans. They produce both diarrheal and systemic illnesses. In industrialized regions, enteric infection produces an inflammatory, sometimes bloody, diarrhea or dysentery syndrome. Campylobacter jejuni is usually the most common cause of community-acquired inflammatory enteritis. In developing regions, the diarrhea may be watery.

39. EMedicine - Campylobacter Infections : Article Excerpt By: Jocelyn Y Ang, MD campylobacter pylori has been reclassified as Helicobacter pylori and willnot be addressed in this chapter. (See Helicobacter pylori Infection.). http://www.emedicine.com/ped/byname/campylobacter-infections.htm

(advertisement) Excerpt from Campylobacter Infections Synonyms, Key Words, and Related Terms: campylobacteriosis, Campylobacteraceae, Campylobacter, Arcobacter Please click here to view the full topic text: Campylobacter Infections Background: Family Campylobacteraceae includes 2 genera, Campylobacter and Arcobacter . There are 18 species and subspecies within the genus Campylobacter , 11 of which are considered pathogenic to humans, causing enteric and extraintestinal illnesses. The major pathogens are Campylobacter jejuni and Campylobacter fetus . The following Campylobacter species and subspecies are pathogenic to humans: Enteric C jejuni subspecies jejuni C jejuni subspecies doylei Campylobacter coli Campylobacter upsaliensis Campylobacter lari C fetus subspecies fetus Campylobacter hyointestinalis Campylobacter concisus Extraintestinal C jejuni subspecies jejuni Campylobacter upsaliensis C lari C fetus subspecies fetus C concisus Campylobacter sputorum Campylobacter curvus Campylobacter rectus Campylobacter pylori has been reclassified as Helicobacter pylori and will not be addressed in this chapter. (See

40. The Mayne Florey Medal Winner 1998 SJ, Phillips M, Waters TE, Sanderson CR (1988) A prospective doubleblind trialof duodenal ulcer relapse after eradication of campylobacter pylori, Lancet 2 http://www.tallpoppies.net.au/floreymedal/winner1998.htm

Mayne Florey Medal 1998 Award For the discovery of the Helicobacter Pylori the causative agent in Gastritis and Gastric Ulceration The winners of the inaugural Florey Medal, awarded in 1998, were Dr Robin Warren of the Department of Pathology, Royal Perth Hospital, Western Australia, and Professor Barry Marshall of the Department of Medicine, University of Western Australia. The nominated achievement for which these scientists won the Medal was their identification of a new bacterium, Helicobacter pylori , and their discovery that this bacterium was the cause of both gastritis (inflammation of the stomach) and of gastric ulcer. These discoveries have had a profound effect on both the management of gastroduodenal disease, and the clinical practice of gastroenterology. What Warren and Marshall did, in chronological order,was to: notice that inflammation of the stomach (gastritis) was associated with the presence of a bacterium (Warren); study 100 patients, and discover that this bacterium was present in every patient who suffered from a duodenal ulcer (Warren and Marshall);

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