1. Diabetic Neuropathies - Neuro-Patient Resource Centre - Montreal Neurological Ho Details about diabetic neuropathies, including the types, who gets it, testing and what can be done.Category Health Conditions and Diseases diabetic neuropathies......diabetic neuropathies Information for patients and their families. Diabetic truncalneuropathy This is also one of the less common diabetic neuropathies. http://www.mni.mcgill.ca/neuropatient/fs_dia.html

Neuro-Patient Resource Centre Room 355 Montreal Neurological Hospital 3801 University Street Montreal, Quebec Canada H3A 2B4 Tel: (514) 398-5358 Email: infoneuro@muhc.mcgill.ca McGill University Health Centre (MUHC) Montreal Neurological DIABETIC NEUROPATHIES Information for patients and their families John D. Stewart, MBBS, FRCP(C), Neurologist, Montreal Neurological Hospital/Institute Last reviewed: October,1999 Introduction What Are Peripheral Nerves? Types Of Diabetic Neuropathy Which Diabetics Get Neuropathy? ... What Can Be Done About Neuropathy Introduction Many diabetics go through life with few if any complications from their diabetes. However in the same way that diabetes may damage a variety of organs in the body, it can produce damage to the peripheral nerves, giving rise to a variety of "peripheral neuropathies". What Are Peripheral Nerves? Peripheral nerves are like electrical wires. They run from the spinal cord to the muscles and from the sensory organs in the skin and joints back to the spinal cord. They work by conducting electrical impulses that either signal a muscle to contract or signal when your skin has been exposed to a stimulus such as touch, warmth or cold. Thus good peripheral nerve function is important for muscle strength, good sensation, good coordination and agility. Peripheral nerves, like all other cells in the body, are living structures that require energy. This is provided by glucose and other substances. It is thought that in diabetes the biochemical milieu of the nerves can be abnormal and this will ultimately lead to nerve fiber damage.

2. Diabetic Neuropathies: The Nerve Damage Of Diabetes diabetic neuropathies are a family of nerve disorders caused by diabetes. Peoplewith diabetes can, over time, have damage to nerves throughout the body. http://www.niddk.nih.gov/health/diabetes/pubs/neuro/neuro.htm

Causes Symptoms Types of Diabetic Neuropathy Neuropathy Affects Nerves Throughout the Body ... For More Information Diabetic neuropathies are a family of nerve disorders caused by diabetes. People with diabetes can, over time, have damage to nerves throughout the body. Neuropathies lead to numbness and sometimes pain and weakness in the hands, arms, feet, and legs. Problems may also occur in every organ system, including the digestive tract, heart, and sex organs. People with diabetes can develop nerve problems at any time, but the longer a person has diabetes, the greater the risk. An estimated 50 percent of those with diabetes have some form of neuropathy, but not all with neuropathy have symptoms. The highest rates of neuropathy are among people who have had the disease for at least 25 years. Diabetic neuropathy also appears to be more common in people who have had problems controlling their blood glucose levels, in those with high levels of blood fat and blood pressure, in overweight people, and in people over the age of 40. The most common type is peripheral neuropathy, also called distal symmetric neuropathy, which affects the arms and legs. Causes The causes are probably different for different varieties of diabetic neuropathy. Researchers are studying the effect of glucose on nerves to find out exactly how prolonged exposure to high glucose causes neuropathy. Nerve damage is likely due to a combination of factors:

3. Diabetic Neuropathy; Diabetes Mellitus Serwis Katalog w Wirtualna Polska S.A. pierwszy portal w Polsce. http://www.neuro.wustl.edu/neuromuscular/nother/diabetes.htm

Front Search Index Links ... Patient Info Neuromuscular disorders Symmetric neuropathies Chronic Distal sensory/autonomic Autonomic ... Mononeuritis multiplex Predisposition to immune PN CIDP ? Diabetic amyotrophy Perineuritis Muscle infarction Overview: Diabetes Diabetes Classification Type 1: IDDM Type 2: NIDDM Other ... Screening Neuropathy: General From NLM Drs. Banting and Best In The Laboratory CLASSIFICATION OF DIABETES MELLITUS Type 1 : Insulin-Dependent Diabetes Mellitus (IDDM) Clinical Body weight: Usually lean Immune: Increased incidence of associated autoimmune phenomena Metabolism: Ketosis prone Treatment: Insulin Pathology b cell destruction Usually leads to absolute insulin deficiency Etiologies Immune-mediated: Associated with antibodies to Insulin: 50% to 90%; Higher titers in young children Glutamate decarboxylase : 80%; Adult onset type IA Tyrosine phosphatase-like molecules b Glycolipids: GT3 ganglioside; ? Sulfatide; ? GM2-I Cytoplasmic islet cell antigens (ICA) Genetic HLA Class II DR-DQ Linkage Patterns and IDDM Susceptibility in Whites Main susceptibility haplotypes in Caucasians (95%) HLA-DR2: With 0102, 0502 and 1601

4. HONselect - Diabetic Neuropathies diabetic neuropathies. MeSH definition Peripheral, autonomic, and cranial nerve disorders that are associated with http://www.hon.ch/HONselect/Selection/C19.246.447.html

HONselect: Introduction Search Browse Favourites List of Rare Disease add HONselect Contents on "Diabetic Neuropathies": MeSH hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Wondering about the holiday blues! MeSH Hierarchy English French German Spanish Portuguese MeSH Broader term(s) Diseases Endocrine Diseases Diabetes Mellitus Diseases Nutritional and Metabolic Diseases Metabolic Diseases Diabetes Mellitus Diseases Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Diabetic Neuropathies MeSH definition Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) Subheadings : complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy MeSH Narrow term(s) Diabetic Foot Accepted term(s) -Diabetic Amyotrophy -Diabetic Autonomic Neuropathy -Diabetic Neuralgia -Diabetic Polyneuropathy Browse New search MEDLINE 's articles for " Diabetic Neuropathies English French German Spanish Portuguese All categories

5. Diabetic Neuropathies diabetic neuropathies up. Related topics http://omni.ac.uk/browse/mesh/detail/C0011882L0011882.html

Diabetic Neuropathies [up] Related topics: broader Diabetes Mellitus Peripheral Nervous System Diseases other Brachial Plexus Neuropathies Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Non-Insulin-Dependent Diabetes, Gestational ... Polyneuropathies narrower Diabetic Foot Diabetic neuropathy A patient-oriented leaflet about diabetic neuropathy, a nerve disorder caused by diabetes. The leaflet provides a description of the different types of the disorder, along with an explanation of the causes, symptoms, diagnosis, and treatment. There is a section on further reading and resources. Published on the Web by the American Pain Foundation (APF), this leaflet may have a slight US bias. Diabetic Neuropathies Patient Education Handout [Publication Type] Last modified 28/Mar/2003 [Low Graphics]

6. PNS Meeting Poster Abstracts - Diabetic And Other Metabolic Neuropathies Diabetic and Other Metabolic Neuropathies Abstracts Poster Session 3 THE INFLUENCE OF MOMORDICA CHARANTIA FRUIT JUICE ON PERIPHERAL NERVE STRUCTURE IN EXPERIMENTAL DIABETES Ahmed I., Sharma A.K., Samad P.A. and suggest a potential effect of antiinflammatory and/or anti-immune drugs in the treatment of diabetic neuropathies. http://pns.ucsd.edu/PostH.abstracts.html

Back to Program PNS Home Diabetic and Other Metabolic Neuropathies Abstracts Poster Session 3 THE INFLUENCE OF MOMORDICA CHARANTIA FRUIT JUICE ON PERIPHERAL NERVE STRUCTURE IN EXPERIMENTAL DIABETES Ahmed I. , Sharma A.K., Samad P.A. Faculty of Med., United Arab Emirates University, Al Ain, UAE Momordica charantia fruit is traditionally used as a vegetable and is known to have hypoglycemic effect in human and experimental diabetes. Ultrastructural observations were made on myelinated fibers in the tibial nerve of streptozotocin-diabetic rats. Four groups of male Wistar rats, aged 12 weeks were studied over a period of four months: untreated diabetic rats, diabetic rats treated with M charantia, controls treated with M charantia and age-matched controls. Blood glucose concentrations were significantly reduced in M charantia M charantia treated diabetic animals, these parameters were intermediate between untreated diabetics and age-matched controls without showing significant difference when compared with either group. The axon to fiber ratio ('g'ratio) did not differ between any of the experimental groups. In conclusion, the administration of M charantia fruit juice reduced blood glucose levels and partially corrected the structural abnormalities of peripheral nerves in experimental diabetes.

7. (9369-391) Diabetic Neuropathies Features And Mechanisms diabetic neuropathies Features and Mechanisms Douglas W. Zochodne diabetic neuropathies include both focal neuropathies and diffuse polyneuropathy. http://brainpathology.upmc.edu/vol9/0902/0902a14.htm

8. NIDDK : Health Information : Diabetes Clearinghouse of diabetes information.Category Health Conditions and Diseases Diabetes Brochures...... Diabetes Prevention Program; Diabetic Eye Disease; diabetic neuropathiesThe Nerve Damage of Diabetes; Diet and Diabetes; Eating and http://www.niddk.nih.gov/health/diabetes/diabetes.htm

Quick Links for Investigators Office of the Director Extramural Activities Intramural Research Nutrition Research Coordination Office of Minority Health Research NIDDK Home Health Information : Diabetes Other resources Diabetes Dateline A newsletter from NIDDK. National Diabetes Information Clearinghouse (NDIC) An information dissemination service of NIDDK. National Diabetes Education Program (NDEP) A federally sponsored initiative that involves public and private partners to improve the treatment and outcomes for people with diabetes, to promote early diagnosis, and ultimately to prevent the onset of diabetes. Directory of Diabetes Organizations Links to national organizations serving patients and professionals concerned about diabetes. Bibliographic Searches on Diabetes Diabetes Diabetes topics Research Easy-to-read publications Spanish-language publications ... Order forms Diabetes topics Each of the topics below exists as a booklet or fact sheet. Copies may be ordered from the National Diabetes Information Clearinghouse Alternative Therapies for Diabetes Am I at Risk for Type 2 Diabetes?

9. Diabetes Voice diabetic neuropathies diabetic neuropathies are a family of nerve disorderscaused by diabetes. People with diabetes can, over time http://www.diabetesvoice.net/neuropathies.html

Home Diabetes Type I Type II ... Sources to contact Other Health Issues Aids Gun Control Resources Contact Us Diabetic Neuropathies Diabetic neuropathies are a family of nerve disorders caused by diabetes. People with diabetes can, over time, have damage to nerves throughout the body. Neuropathies lead to numbness and sometimes pain and weakness in the hands, arms, feet, and legs. Problems may also occur in every organ system, including the digestive tract, heart, and sex organs. People with diabetes can develop nerve problems at any time, but the longer a person has diabetes, the greater the risk. An estimated 50 percent of those with diabetes have some form of neuropathy, but not all with neuropathy have symptoms. The highest rates of neuropathy are among people who have had the disease for at least 25 years. Diabetic neuropathy also appears to be more common in people who have had problems controlling their blood glucose levels, in those with high levels of blood fat and blood pressure, in overweight people, and in people over the age of 40. The most common type is peripheral neuropathy, also called distal symmetric neuropathy, which affects the arms and legs. Recommended Site: Best of the Web: American Diabetes Association Oxygen

10. ClinicalTrials.gov - Linking Patients To Medical Research: Browse: Diabetic Neur in Patients with Diabetes. Conditions diabetic neuropathies; Diabetes Mellitus, InsulinDependent; Diabetes Mellitus, http://clinicaltrials.gov/ct/gui/c/a2b/screen/BrowseAny?path=%2Fbrowse%2Fby-cond

11. Diabetes Voice Types of diabetic neuropathies diabetic neuropathies can be classifiedas peripheral, autonomic, proximal, and focal. Each affects http://www.diabetesvoice.net/types.html

Home Diabetes Type I Type II ... Sources to contact Other Health Issues Aids Gun Control Resources Contact Us Types of Diabetic Neuropathies Diabetic neuropathies can be classified as peripheral, autonomic, proximal, and focal. Each affects different parts of the body in different ways. Peripheral neuropathy causes either pain or loss of feeling in the toes, feet, legs, hands, and arms. Autonomic neuropathy causes changes in digestion, bowel and bladder function, sexual response, and perspiration. It can also affect the nerves that serve the heart and control blood pressure. Autonomic neuropathy can also cause hypoglycemia (low blood sugar) unawareness, a condition in which people no longer experience the warning signs of hypoglycemia. Proximal neuropathy causes pain in the thighs, hips, or buttocks and leads to weakness in the legs. Focal neuropathy results in the sudden weakness of one nerve, or a group of nerves, causing muscle weakness or pain. Any nerve in the body may be affected. Recommended Site: Best of the Web: American Diabetes Association Oxygen

12. DIABETIC NEUROPATHIES Jennifer Zebrack, MD. diabetic neuropathies. Clinic Conference March 25 29, 2002 http://www.intmed.mcw.edu/ClinicConf/03-25-02%20res%20Diabetic%20Neuropathy.htm

Jennifer Zebrack, MD DIABETIC NEUROPATHIES Clinic Conference: March 25 - 29, 2002 Resident Version References: Vinik AI. Diabetic neuropathy: pathogenesis and therapy. American Journal of Medicine. Aug 1999;107(2B):17S-26S. Available on OVID http://ovid.lib.mcw.edu/ Smieja M, et al., for the International Cooperative Group for Clinical Examination Research. Clinical examination for the detection of protective sensation in the feet of diabetic patients. Journal of General Internal Medicine. July 1999;14:418-24. Introduction Diabetic neuropathy is the most frequent symptomatic complication of diabetes and encompasses a wide range of abnormalities affecting both the peripheral and autonomic nervous systems. These neuropathies may be disabling and even contribute to mortality in diabetic patients. Other than improved glucose control, current therapies are primarily palliative and supportive. Peripheral Neuropathy Distal, symmetric polyneuropathy is the most common form of diabetic peripheral neuropathy and usually occurs in a stocking-glove distribution. Patients with peripheral neuropathy are at risk for long-term complications of ulceration, infection, and amputation. All diabetic patients should receive an annual foot exam, including visual inspection, peripheral pulses, and sensation. The Semmes-Weinstein monofilament exam is currently the best screening test to detect clinically significant neuropathy. Patient education regarding foot care and daily monitoring for skin breakdown is essential. Pharmacologic therapies for painful peripheral neuropathy include, but are not limited to, tricyclic antidepressants, antiepileptics, and topical capsaicin.

13. HONselect - Peripheral Nervous System Diseases Information about the main diseases of the peripheral nerves external to the brain and spinal cord.Category Health Conditions and Diseases Peripheral Nervous System...... Brachial Plexus Neuropathies, Complex Regional Pain Syndromes. diabetic neuropathies,GuillainBarre Syndrome. Mononeuropathies, Nerve Compression Syndromes. http://www.hon.ch/HONselect/Selection/C10.772.html

HONselect: Introduction Search Browse Favourites List of Rare Disease add HONselect Contents on "Peripheral Nervous System Diseases": MeSH hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Wondering about the holiday blues! MeSH Hierarchy English French German Spanish Portuguese MeSH Broader term(s) Diseases Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases MeSH definition Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves. Subheadings : complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy MeSH Narrow term(s) Brachial Plexus Neuropathies Complex Regional Pain Syndromes Diabetic Neuropathies Guillain-Barre Syndrome Mononeuropathies Nerve Compression Syndromes Neuralgia Neuritis Peripheral Nervous System Neoplasms Polyneuropathies Acrodynia Amyloid Neuropathies Isaacs Syndrome Neurofibromatosis 1 Pain Insensitivity, Congenital

14. Diabetic Neuropathies Névrites Diabetiques La suivante nest quune liste partielle. . diabetic neuropathies Information for patients and their families. http://www.mni.mcgill.ca/neuropatient/Diabetic%20neuropathies.PDF

15. Diabetic Foot Diabetic Foot up. Related topics broader, diabetic neuropathies.other, Diabetic Retinopathy. Clinical guideline for type 2 diabetes http://omni.ac.uk/browse/mesh/detail/C0206172L0250062.html

Diabetic Foot [up] Related topics: broader Diabetic Neuropathies other Diabetic Retinopathy Clinical guideline for type 2 diabetes : prevention and management of foot problems This evidence-based clinical guideline for type 2 diabetes-prevention and management of foot problems is produced by the Royal College of General Practitioners in collaboration with the British Diabetic Association, Royal College of Physicians and the Royal College of Nursing. Published in April 2000, this guideline provides information on how to develop a foot care guideline, background information on diabetic foot care, care of the diabetic foot without complications, the foot at raised risk of complications, and the ulcerated foot. Details of research and methods used in the guideline development process are all provided. This guideline will be reviewed in April 2003. Available in PDF, which requires Adobe Acrobat Reader, this guideline is 101 pages long and is aimed at clinical staff working in primary and secondary care. Diabetes Mellitus, Non-Insulin-Dependent / complications

16. Diabetic Neuropathies: An Overview diabetic neuropathies affect up to 60% of diabetics. Bethesda, MD. Vinik, A., etal., diabetic neuropathies, Diabetes Care, December 1992, pp. 19261975. http://diabetes.about.com/library/blNIHneuropathy.htm

zfp=-1 About Diabetes Search in this topic on About on the Web in Products Web Hosting Diabetes with Paula Ford-Martin Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects ESSENTIALS Carbs and Diabetes About Diabetes Recipe Box Tools for Diabetes Control ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Diabetic Neuropathy: The Nerve Damage of Diabetes What Is Diabetic Neuropathy? How Common Is Diabetic Neuropathy? What Causes Diabetic Neuropathy? What Are the Symptoms of Diabetic Neuropathy? ... Additional Reading What Is Diabetic Neuropathy Diabetic neuropathy is a nerve disorder caused by diabetes. Symptoms of neuropathy include numbness and sometimes pain in the hands, feet, or legs. Nerve damage caused by diabetes can also lead to problems with internal organs such as the digestive tract, heart, and sexual organs, causing indigestion, diarrhea or constipation, dizziness, bladder infections, and impotence. In some cases, neuropathy can flare up suddenly, causing weakness and weight loss. Depression may follow. While some treatments are available, a great deal of research is still needed to understand how diabetes affects the nerves and to find more effective treatments for this complication. DCCT: Can Diabetic Neuropathy Be Prevented?

17. Diabetic Neuropathy - Peripheral And Autonomic Neuropathies Of Diabetes know what to look for. diabetic neuropathies An Overview Diabeticneuropathies affect up to 60% of diabetics. Learn more about the http://diabetes.about.com/cs/neuropathy/

zfp=-1 About Diabetes Search in this topic on About on the Web in Products Web Hosting Diabetes with Paula Ford-Martin Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects ESSENTIALS Carbs and Diabetes About Diabetes Recipe Box Tools for Diabetes Control ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Neuropathies of Diabetes Guide picks Explore these important resources on peripheral, diffuse, and autonomic neuropathies of diabetes. Autonomic Dysfunction - The "Other" Neuropathy Although it can cause sudden heart attack, impotence, incontinence, and a host of other serious medical problems, 92% of the diabetic population are unaware of this complication, and a mere 2% are regularly tested for it. Diagnosis can be simple, if you and your doctor know what to look for. Diabetic Neuropathies: An Overview Diabetic neuropathies affect up to 60% of diabetics. Learn more about the symptoms, causes, diagnosis, and treatment of this complication in this comprehensive overview reprinted from the National Institutes of Health. Includes information on peripheral, autonomic, and focal neuropathies. Foot Disease Foot ulcers and nerve damage are just two possible complications of diabetes. Proper foot care is critical to maintaining good health for the diabetic. Explore these informative educational resources on diabetic foot care

18. Diabetic Neuropathies diabetic neuropathies. Back to previous level Diabetic Foot SearchPUBMED for Diabetic Foot All Review Therapy Diagnosis; The Prevention http://www.ohsu.edu/cliniweb/C10/C10.772.267.html

Diabetic Neuropathies Back to previous level Diabetic Foot Search PUBMED for Diabetic Foot: All Review Therapy Diagnosis ... The Prevention and Treatment of Complications of Diabetes Mellitus: Foot Problems: CDC

19. Peripheral Nervous System Diseases Coll. of Wisconsin. diabetic neuropathies 1 more specific term/s, 1 more link/sSearch PUBMED for diabetic neuropathies All Review Therapy Diagnosis; http://www.ohsu.edu/cliniweb/C10/C10.772.html

Peripheral Nervous System Diseases Back to previous level Acrodynia Search PUBMED for Acrodynia: All Review Therapy Diagnosis Amyloid Neuropathies Search PUBMED for Amyloid Neuropathies: All Review Therapy Diagnosis ... Autonomic Nervous System Diseases [5 more specific term/s, 4 more link/s] Search PUBMED for Autonomic Nervous System Diseases: All Review Therapy Diagnosis ... Cranial Nerve Diseases [8 more specific term/s, 31 more link/s] Search PUBMED for Cranial Nerve Diseases: All Review Therapy Diagnosis ... Demyelinating Diseases [2 more specific term/s, more link/s] Search PUBMED for Demyelinating Diseases: All Review Therapy Diagnosis ... Diabetic Neuropathies [1 more specific term/s, 1 more link/s] Search PUBMED for Diabetic Neuropathies: All Review Therapy Diagnosis ... Nerve Compression Syndromes [4 more specific term/s, 4 more link/s] Search PUBMED for Nerve Compression Syndromes: All Review Therapy Diagnosis ... Neuralgia [4 more specific term/s, 20 more link/s] Search PUBMED for Neuralgia: All Review Therapy Diagnosis ... Neuritis [5 more specific term/s, more link/s] Search PUBMED for Neuritis: All Review Therapy Diagnosis ... Neuropathies, Hereditary Motor and Sensory

20. Gerald W Grass, MD LLC Diabetic Neuropathies CraigPENS is very effective for the treatment of diabetic neuropathies.Please SCIENTIFIC ABSTRACTS. diabetic neuropathies. Percutaneous http://www.grassmedical.com/Abstracts/Diabetic_Neuropathies.htm

Home Services About Us In The News ... Contact Us SCIENTIFIC ABSTRACTS Diabetic Neuropathies Percutaneous electrical nerve stimulation: a novel analgesic therapy for diabetic neuropathic pain. Hamza MA, White PF, Craig WF, Ghoname ES, Ahmed HE, Proctor TJ, Noe CE, Vakharia AS, Gajraj N. Eugene McDermott Center for Pain Management, Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, 75235, USA. OBJECTIVE: To evaluate the use of percutaneous electrical nerve stimulation (PENS) in the management of patients with painful diabetic peripheral neuropathy. RESEARCH DES lower extremities were randomly assigned to receive active PENS (needles with electrical stimulation at an Diabetes Care 2000 Mar;23(3):365-70 Acupuncture for the treatment of chronic painful peripheral diabetic neuropathy: a long-term study. Abuaisha BB, Costanzi JB, Boulton AJ. Department of Medicine, Manchester Royal Infirmary, University of Manchester, UK.

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