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         Empty Sella Syndrome:     more detail
  1. The Official Patient's Sourcebook on Empty Sella Syndrome: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2003-04-08
  2. Empty sella syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Scott, MS, CGC Polzin, 2005

1. NINDS Empty Sella Syndrome Information Page
Information sheet compiled by NINDS compiled by NINDS, the National Institute of Neurological Disorders Category Health Conditions and Diseases empty sella syndrome......empty sella syndrome information sheet compiled by the National Institute ofNeurological Disorders and Stroke (NINDS). More about empty sella syndrome,
http://www.ninds.nih.gov/health_and_medical/disorders/emptysella.htm
National Institute of Neurological Disorders and Stroke Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Browse all disorders Browse all health
organizations
More about
Empty Sella Syndrome
Studies with patients Research literature Press releases
Search NINDS... (help) Contact us My privacy NINDS is part of the
National Institutes of

Health
NINDS Empty Sella Syndrome Information Page
Reviewed 07-01-2001 Get Web page suited for printing
Email this to a friend or colleague

Table of Contents (click to jump to sections) What is Empty Sella Syndrome ?
Is there any treatment?

What is the prognosis?
What research is being done? ... Organizations What is Empty Sella Syndrome ? Empty sella syndrome is a rare congenital disorder that occurs when an empty space in the brain fills with cerebrospinal fluid as a result of a deformity in the brain. Individuals with the disorder may have unusual facial features. Other symptoms may include short stature, increased bone density, headaches, and vision problems. Empty sella syndrome may also be caused by other disorders or a problem caused by some medical intervention, such as surgery. The disorder is particularly common in middle-age, obese women. Empty sella syndrome may be confused with pituitary disorders. Is there any treatment?

2. Endocrinology - Empty Sella Syndrome- Methodist Health Care System, Houston, Tex
Methodist Health Care System explains what this syndrome is, the symptoms, diagnosis and its treatment.
http://www.methodisthealth.com/endocrin/sella.htm

Endocrinology

Home Page
Endocrinología (en español)
Clinical Services
The Methodist Hospital

Methodist Diagnostic Hospital

Methodist Sugar Land Hospital

Methodist Willowbrook Hospital
...
Appointment

Empty Sella Syndrome What is empty sella syndrome?
Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal size or small. What are the symptoms of empty sella syndrome? Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose. How is empty sella syndrome diagnosed? In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
  • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray

3. What Is Empty Sella Syndrome? - Endocrinology Health Guide
A look at this disorder and the diagnosis, symptoms and treatment.
http://www.umm.edu/endocrin/sella.htm

Endocrinology Health Guide...
Pituitary Gland Disorders... Pituitary Tumors Acromegaly ... Glossary
Related Resources Within UMM Endocrinology Joslin Diabetes Center School of Medicine Endocrinology Site Endocrinology Health Guide
Empty Sella Syndrome
What is empty sella syndrome?
Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal or small in size.
What are the symptoms of empty sella syndrome?
Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose.
How is empty sella syndrome diagnosed?
In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
  • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray

4. MEDLINEplus Medical Encyclopedia: Empty-sella Syndrome
the condition is referred to as the empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical
http://www.nlm.nih.gov/medlineplus/ency/article/000349.htm
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The pituitary gland Definition Return to top Absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that partly surrounds the gland. Causes, incidence, and risk factors Return to top The pituitary gland is a small, oval gland at the base of the brain. It makes several hormones that control the function of other glands in the body including the thyroid gland, adrenal glands, and gonads (ovaries or testes). The pituitary gland is partly surrounded by a bony structure called the sella turcica (Turkish saddle). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as the empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury (e.g., surgery, head trauma, radiation therapy), the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding on radiological imaging of the brain. Pituitary function is usually normal, and patients do not have any symptoms. The hormone prolactin is mildly elevated in 10-15 % of patients, and the elevated prolactin may interfere with normal function of the testes or ovaries. Medications that suppress prolactin production (e.g., bromocriptine) are effective in correcting the problem.

5. Empty Sella Syndrome
a CHORUS notecard document about empty sella syndrome Disclaimer. Feedback. Search. empty sella syndrome. etiology. idiopathic
http://chorus.rad.mcw.edu/doc/00517.html
CHORUS Collaborative Hypertext of Radiology Nervous system
Feedback

Search
empty sella syndrome
etiology
  • idiopathic
    • most commonly reported in middle-aged obese women (a/w DM, HTN, normal pituitary function)
  • secondary
  • familial (very rare)
xray findings:
  • sella normal or increased
  • intrasellar herniation of subarachnoid space
  • symptoms:
    • headache, visual disorders
    • +/- decreased pituitary function
    • CSF rhinorrhea
    Charles E. Kahn, Jr., MD - 2 February 1995
    Last updated 14 March 2001

    Medical College of Wisconsin
  • 6. Pituitary: Empty Sella Syndrome 49424 P
    Pituitary empty sella syndrome 49424 P empty sella syndrome is a radiologic term used to describe a rare condition.
    http://www.echt.chm.msu.edu/courseware/blockII/Pathology/Pituitary_17f.html
    echt home block II pathology pituitary menu
    Pituitary: Empty Sella Syndrome 49424 P
    Empty sella syndrome is a radiologic term used to describe a rare condition. Herniation of the arachnoid through a defect in the diaphragma sella or elswhere may result in pressure atrophy of the gland, resulting in an "empty" sella. The enlarged sella may actually contain sufficient functional tissue flattened along the base. Such patient's may not exhibit marked hypopituitarism. This empty sella was an incidental finding at autopsy of a 64 year old male.

    7. Empty Sella Syndrome Resources On The Internet
    millions of published articles for news on empty sella syndrome. The eLibrary newspaper and magazine archive contains
    http://www.healthcyclopedia.com/empty_sella_syndrome.html

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    millions of published articles for news on Empty Sella Syndrome
    The eLibrary newspaper and magazine archive contains articles from current and back issues of hundreds of publications, including: Modern Medicine Aging The Ardell Wellness Report HealthFacts The Journal of Environmental Health Medical Post Medical Update Men's Health and the National Women's Health Report
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    To access the full text of articles, sign up for a seven-day no-risk free trial subscription to eLibrary.
    Web Directory
    Web Links:
    Empty Sella - eGroups: Email list available to anyone interested in sharing information and/or support for persons affected by this syndrome. Empty Sella Syndrome - Methodist Health Care System explains what this syndrome is, the symptoms, diagnosis and its treatment. Empty Sella Syndrome - A look at what this disease is, its symptoms, how it is diagnosed and its treatment. Empty Sella Syndrome - A brief look at this disease, the causes and symptoms. Empty Sella Syndrome - Information sheet compiled by NINDS compiled by NINDS, the National Institute of Neurological Disorders and Stroke.

    8. NINDS - News And Events
    Sorry! There are no press releases for empty sella syndrome. Useyour browser's Back button to return to your previous activity.
    http://www.ninds.nih.gov/health_and_medical/news.htm?url=/health_and_medical/dis

    9. Endocrinology Spanish Content - Empty Sella Syndrome - Methodist Health Care Sys
    Translate this page El Síndrome de la Silla Vacía ¿Qué es el síndrome de la sillavacía? El síndrome de la silla vacía es común en mujeres
    http://www.methodisthealth.com/spanish/endocrin/sella.htm

    Página Principal de la Endocrinología
    Servicios Clínicos
    The Methodist Hospital Metabolic and Endocrine Disease Service

    Methodist Diagnostic Hospital

    Methodist Sugar Land Hospital

    Methodist Willowbrook Hospital
    ... La Glándula Pituitaria: Localización y Función
    Los Desórdenes:
    La Acromegalia

    La Diabetes Insípida

    El Síndrome de la Silla Vacía

    El Hipopituitarismo
    ... El Páncreas: Localización y Función Los Desórdenes: La Pancreatitis El Cáncer Pancreático Las Glándulas Adrenales: Localización y Función Los Desórdenes: Las Glándulas Adrenales Hipofuncionantes/La Enfermedad de Addison Las Glándulas Adrenales Hiperfuncionantes/El Síndrome de Cushing Los Tumores / El Feocromocitoma La Glándula Tiroides: Localización y Función ... Las Pruebas de Función de la Tiroides Los Desórdenes: El Hipertiroidismo/La Enfermedad de Graves/El Bocio Nodular Tóxico/La Tiroiditis El Hipotiroidismo La Tiroiditis de Hashimoto Los Tumores ... Las Glándulas Paratiroides: Localización y Función Los Desórdenes: El Hiperparatiroidismo El Hipoparatiroidismo Los Tumores Las Glándulas Reproductoras ... Plan Para Hacer una Cita Médica Póngase en Contacto con Nosostros: Referencia Médica Plan Para Hacer una Cita Médica Preguntas Generales Planes de Salud ... Directorio de Médicos El Síndrome de la Silla Vacía ¿Qué es el síndrome de la silla vacía?

    10. Empty Sella Syndrome
    empty sella syndrome is a radiological finding where spinal fluid is found within the space created for the pituitary.
    http://www.pituitary.org/disorders/emptysellasyndrome.php

    11. Pituitary Network Association - Disorders - Empty Sella Syndrome
    Pituitary Network Association Pituitary Network Association - Disorders- empty sella syndrome. empty sella syndrome. Empty sella
    http://www.pituitary.com/disorders/emptysellasyndrome.php
    Home Join Now Donate For Reporters ... Members
    Empty Sella Syndrome Empty sella syndrome is a radiological finding where spinal fluid is found within the space created for the pituitary. The most common cause is a large opening in the diaphragma sellae, a membrane which sits on top of the pituitary and protects it in its socket within the bones at the base of the skull. When this opening is large, the spinal fluid pressure is transmitted to the pituitary and flattens it out within the sella. Generally, in this situation, pituitary function is normal, but a number of patients have headaches, mild hyperprolactinemia, galactorrhea, and irregular menses. In most cases, however, the pituitary functions normally as evidenced by normal thyroid functions, normal tests of adrenal function, normal somatomedin-C levels, and regular menses. Some patients have empty sella syndrome as a result of other processes such as neurosarcoidosis pituitary tumors that have degenerated, etc. Rare patients have a congenital empty sella and a coexisting pituitary tumor. Symptoms
    • unusual facial features
    • increased bone density
    • headaches
    • vision problems
    Diagnosis
  • x-ray
  • CT (CAT) scan
  • Magnetic resonance imaging (MRI) Treatment Unless the disorder results in other medical problems, treatment is symptomatic and supportive. In some cases, surgery may be needed.
  • 12. Endocrinology - Empty Sella Syndrome
    Medical Encyclopdia article about Emptysella syndrome A resource with information on over 4000 medical topics including Empty-sella syndrome
    http://www.sw.org/clinical_content/adult/endocrin/sella.htm
    Empty Sella Syndrome What is empty sella syndrome?
    Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal size or small.
    What are the symptoms of empty sella syndrome?
    Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose.
    How is empty sella syndrome diagnosed?
    In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
    • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray magnetic resonance imaging (MRI) - a non-invasive procedure that produces two-dimensional views of an internal organ or structure, especially the brain or spinal cord

    13. Pituitary Forums - Powered By VBulletin
    Robert. empty sella syndrome empty sella syndrome is a radiological finding wherespinal fluid is found within the space created for the pituitary. 4, 2,
    http://www.pituitary.com/Forums/index.php
    Home Join Now Donate For Reporters ... Shopping Cart Pituitary Forums
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    If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. Members: 484, Threads: 270, Posts: 1,126
    Welcome to our newest member, Suedan The time now is 11:51 PM.
    You last visited: 03-30-2003 11:51 PM.
    Forum Posts Threads Last Post Moderator Pituitary Disorder Issues
    The many issues we deal with every day. 08:08 PM
    by gretchenb Robert Acromegaly
    Acromegaly is a systemic condition caused in over 98% of cases by an adenoma of the pituitary gland that secretes excessive growth hormone (GH). 03:25 PM
    by Robert Robert Addison's
    Addison's disease occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. 09:28 PM by jmg Robert Craniopharyngioma Craniopharyngiomas are intracranial tumors that are typically both cystic and solid in structure. They occur most commonly in childhood and adolescence and in later adult life after age 50 years. 10:26 PM by Robert Cushing's Syndrome Cushing's Syndrome is a debilitating endocrine disorder characterized by excessive cortisol levels in the blood which may be the result of a tumor of the pituitary gland, adrenal glands or from tumors or cancer arising elsewhere in the body (ectopic

    14. Endocrinology - Empty Sella Syndrome
    empty sella syndrome What is empty sella syndrome? empty sella syndrome is common in women who are overweight or have high blood pressure.
    http://www.uuhsc.utah.edu/healthinfo/adult/Endocrine/sella.htm
    Empty Sella Syndrome What is empty sella syndrome?
    Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal size or small.
    What are the symptoms of empty sella syndrome?
    Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose.
    How is empty sella syndrome diagnosed?
    In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
    • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray magnetic resonance imaging (MRI) - a non-invasive procedure that produces two-dimensional views of an internal organ or structure, especially the brain or spinal cord

    15. Nervous System - CHORUS
    leukoencephalopathy; DykeDavidoff-Masson syndrome; dysmyelinating disease;ectopic thyroid; empty sella syndrome; encephalocele; enhancing
    http://chorus.rad.mcw.edu/index/1.html
    CHORUS Collaborative Hypertext of Radiology Search by title
    Nervous system
    Charles E. Kahn, Jr., MD, Editor
    1 January 2003

    Medical College of Wisconsin

    16. Empty Sella Syndrome
    Subject empty sella syndrome Topic Area Neurology General Forum The Neurologyand Neurosurgery Forum Question Posted By KYgal on Wednesday, July 24, 2002
    http://www.medhelp.org/forums/neuro/messages/31907a.html
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    Med Help International

    A not-for-profit organization Questions in The Neurology Forum are being answered by doctors from
    The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Empty Sella Syndrome
    Topic Area: Neurology - General
    Forum: The Neurology and Neurosurgery Forum
    Question Posted By: KYgal on Wednesday, July 24, 2002
    Two years ago, I had surgery to revise a VPshunt (orginialshunt placement in 1987)and two weeks later fenestration of a ventricular cyst via neuroendoscopy. A few weeks later, I ended up with a cerebral abcess and subseqent removal of shunt and 8 wks of Vancomycin IV. MRI following treatment showed empty sella syndrome and microcystic fibromylasia where shunt had been. The neurosurgeon said that the empty sella was nothing to be concerned about.
    Since the surgery, I have had basically no libido, tired all the time, joints ache, difficulty concentrating, poor memory, and now headaches again. Another MRI was done by family Dr. to see if cyst had returned. The MRI showed the same as last. Seen by a neurologist. No one concerned about empty sella. Perhaps it is because I am middle age, overweight, and have hypertension? (yes, I have read about it!) However, I did not have the empty sella syndrome before the surgery and infection, nor did I have these symptoms. Should I be concerned?
    PS> I am usually a very active professional who enjoys hiking, camping, and traveling in my spare time. I now find everything very challenging and have no spare time, because it takes me so long to get things done!

    17. Empty Sella Syndrome CAUSED BY SURGERY
    Subject empty sella syndrome CAUSED BY SURGERY Topic Area Neurology General ForumThe Neurology and Neurosurgery Forum Question Posted By cindy on Sunday
    http://www.medhelp.org/forums/neuro/archive/9173.html
    Advertisement
    Welcome to
    Med Help International

    A not-for-profit organization Questions in The Neurology Forum are being answered by doctors from
    The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Empty Sella Syndrome CAUSED BY SURGERY
    Topic Area: Neurology - General
    Forum: The Neurology and Neurosurgery Forum
    Question Posted By: cindy on Sunday, September 27, 1998
    In 1994 I had a small pineal gland cyst, I had a pituitary gland of normal size and configuration. My problem was not in my brain. My problem was disc problems in the Cervical and Thoracic areas. After my last surgery, I continued to worsen, this time with symptoms which appeared to be autonomic in nature. I have developed all kinds of strange symptoms, some seeming related to the heart. A new brain MRI was done. It shows a Empty Sella. Where did my pituitary gland go to? Do surgeries cause your pituitary gland to disappear and present as an Empty Sella? Could this be causing all these autonomic problems? I have checked your info files and it says that the pituitary gland disappears.

    18. MedWebPlus Subject Diseases And Conditions Brain Diseases
    A, , GO, Michigan State Univeristy College of Human Medicine Pituitaryempty sella syndrome 49424 P. NINDS empty sella syndrome Information Page.
    http://www.medwebplus.com/subject/Diseases_and_Conditions/Brain_Diseases/Empty_S

    19. NINDS Empty Sella Syndrome Information Page
    empty sella syndrome information sheet compiled by the National Institute ofNeurological Disorders and Stroke (NINDS). What is empty sella syndrome ?
    http://accessible.ninds.nih.gov/health_and_medical/disorders/emptysella.htm
    Disorders - National Institute of Neurological Disorders and Stroke (NINDS) Skip menus
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    More about NINDS Empty Sella Syndrome Information Page
  • Studies with patients Research literature Press release
  • NINDS Search (search help) Contact us My privacy NINDS is part of the National Institutes of Health Contact us
    Content for this page
    NINDS Empty Sella Syndrome Information Page
    Reviewed 07-01-2001 Get Web page suited for printing
    Email this to a friend or colleague

    Table of Contents (click to jump to sections)
    What is Empty Sella Syndrome ?

    Is there any treatment?

    What is the prognosis?

    What research is being done?
    ...
    Organizations

    What is Empty Sella Syndrome ?
    Empty sella syndrome is a rare congenital disorder that occurs when an empty space in the brain fills with cerebrospinal fluid as a result of a deformity in the brain. Individuals with the disorder may have unusual facial features. Other symptoms may include short stature, increased bone density, headaches, and vision problems. Empty sella syndrome may also be caused by other disorders or a problem caused by some medical intervention, such as surgery. The disorder is particularly common in middle-age, obese women. Empty sella syndrome may be confused with pituitary disorders.

    20. Health Library - Empty Sella Syndrome
    empty sella syndrome. The primary from of empty sella syndrome is a rare inheriteddisorder of the brain that is transmitted as an autosomal dominant trait.
    http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=

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