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         Erythromelalgia:     more detail
  1. Small fiber neuropathy underlies erythromelalgia.(Skin Disorders): An article from: Family Practice News by Jane Salodof MacNeil, 2006-04-01
  2. Red scrotal syndrome: a localized phenotypical expression of erythromelalgia.(CASE REPORTS)(Case study): An article from: Journal of Drugs in Dermatology by Noel Prevost, Joseph C., III English, 2007-09-01
  3. A case of erythromelalgia: good response to treatment with gabapentin.(CASE REPORTS)(Clinical report): An article from: Journal of Drugs in Dermatology by Ali Murat Ceyhan, Ipek Gurses, et all 2010-05-01
  4. Two cases of erythromelalgia (Mitchell) by Daniel Webster Prentiss, 1897
  5. A case of erythromelalgia,: With microscopical examination of the tissue from an amputated toe, (American journal of the medical sciences) by S. Weir Mitchell, 1899
  6. The occurrence of erythromelalgia in diseases of the spinal cord: An account of ten cases by James Collier, 1898
  7. Erythromelalgia: Report of two cases, with cure. From the clinic of Dr. Otto Lerch, professor of medical diagnosis, postgraduate department, Tulane University by Albert Emile Fossier, 1913
  8. Hysterical rapid respiration, with cases: Peculiar form of rupial skin disease in an hysterial woman by S. Weir Mitchell, 1893

41. Health Library - Erythromelalgia
Your Health. Search. erythromelalgia. erythromelalgia is a rare condition thatprimarily affects the feet and, less commonly, the hands (extremities).
http://yourhealth.stlukesonline.org/Library/HealthGuide/IllnessConditions/topic.

42. Erythromelalgia Information Page Diseases Database
erythromelalgia Information Page. 2 synonyms or equivalents were found.erythromelalgia aka/or Erythermalgia related topics and
http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=4476

43. NORD - National Organization For Rare Disorders, Inc.
erythromelalgia. To purchase fulltext report ($7.50) Copyright 1986, 1987,1988, 1989, 1995, 2001, 2002 Synonyms of erythromelalgia Erythermalgia;
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Erythromelalg

44. Health Library - Erythromelalgia
Advanced Search. erythromelalgia. Self Help Clearinghouse. TEA (The erythromelalgiaAssociation). National network. Founded 1999
http://www.stjosephhealth.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29e

45. Erythromelalgia - General Practice Notebook
medical information from General Practice Notebook. erythromelalgia. This israre condition where the fingers or toes become painful, purple and bloated.
http://www.gpnotebook.co.uk/cache/-328531925.htm
erythromelalgia This is rare condition where the fingers or toes become painful, purple and bloated. Relapses are episodic, often worse in the summer. There is an association with:
  • hypertension polycythaemia rubra vera

Click here for more information...

46. Dermatology.cdlib.org/rxderm-archives/erythromelalgia
erythromelalgia I have a60 yo male with a one-year history of erythromelalgia confined to the feet.
http://dermatology.cdlib.org/rxderm-archives/erythromelalgia
ERYTHROMELALGIA - I have a 60 y.o. male with a one-year history of erythromelalgia confined to the feet. The pt. does not have an elevated platelet count. He has hypertension, controlled with beta blockers. Calcium channel blockers worsened his erythromelalgia symptoms as noted in the literature. Aspirin and other NSAIA's had no effect. Pushing beta blockers had no effect. Any suggestions for treatment? Ethan D. Nydorf, M.D. - I have had great sucess with 40% urea in aquaphor. Bob Aylesworth M.D. - It sounds like the patient might have a Trental deficiency. Haines Ely MD - I have been a silent observer for a few months and have found the discussions interesting and occasionally helpful (esp IRBD). It takes a while to become comfortable with this modality - but the potential for good is great. Yesterday, I saw an 18 year-old woman with burning tender feet for two to three weeks. She's in good general health; a college student active in dance and cheerleading, she takes no medications other than OCP. The exam showed bright red warm feet, no papules or plaques, hands were normal. No edema. I suspect this is erythromelalgia (sometime called erythermelalgia) and can only remember seeing one similar case in the distant past. Three textbooks painted different pictures - not surprising since this is realtively rare. I obtained cbc and chemistries and ua (since thrombocythemia, diabetes and a host of other disease have been associated); held off on any more esoteric studies - recommended elevation, cold compresses and ASA 650 mg qid and will see her back in a week. May use an NSAID if ASA is not helpful. Does this picture suggest any other diagnosis (we see chilblains here commonly, and this looks quite different) and has anyone treated a number of these patients - and what seems to work best? Thank you for your help. David J. Elpern Your address (Hawaii) seems to rule against cold induced diseases such as erythromelalgia. The most common cause of what you are seeing is a mixed corynebacterial infection in sweaty feet. The best treatment is a month or so of erythromycin, orally. Careful exam of the hands usually reveals some fingertip erythema and desquamation as well. Haines Ely Quick search lead to piroxicam rx (JAAD l991-Jan), propranolol rx, and I was wondering about Trental as a possibility? Note that it has been associated with SLE and as a sign of internal malignancy- Diane Thaler Haines, would you say keratolysis exfoliativa is corynebacterium as well? What do you use in people who cannot tolerate erythro? And why do some people get it only in the late Fall through Winter-at least here in cold country. If David's patient does have erthromelalgia, what do you think of Trental rx? Diane Thaler No suggestion for other dxs. However, an elderly woman (already on aspirin) complained of burning feet. Exam showed increased erythema otherwise normal. KOH was neg. Tried Zostrix cream and warned of burning sensation with application. Patient thrilled!! Burning of feet completely resolved within one week. Currently tapering, so do not know if "cured" or controlled by Zostrix cream. Mary K. Cullen I suggest "neuropeptidogenic acral dermatitis" as described in the International Journal of Dermatology by Italian Dermatologists several years ago. Zostrix was very useful. Robert I. Rudolph, M.D., FACP There is a condition called symmetric lividities of the feet. I'm sure it was described in the JAAD about 1987. I've seen it several times usually in young males who are very active in sports. Your patient may have this condition. James G. Rothschild The proper name is acral neuropeptidogenic dysesthesia. Robert I. Rudolph, M.D., FACP If ASA not helpful, would consider something like Zyrtec to treat this as possible pressure urticaria(?from the dancing and cheerleading?) Hal Rehbein Excerpt from Rook's Textbook of Dermatology on CD-Rom "Diffuse erythematous eruptions/Scarlatiniform eruptions Scarlatiniform eruptions (Fig 41-8 . The known causes include the exotoxins of the haemolytic streptococcus and staphylococcus causing scarlet fever, and certain drugs (Chapters 23 and 74). The onset is usually acute and the eruption may be generalized or it may be restricted to localized areas, e.g. the palms and soles. There is a diffuse erythema which may be associated with a burning sensation in the skin and sometimes some itching. There may be fever and variable systemic symptoms. Spontaneous resolution usually occurs in 10-21 days and is often followed by desquamation. There may also be shedding of nails and sometimes of hair. In those cases where no cause is detected recurrences are not infrequent. The presence of an exanthem helps to distinguish scarlet fever from other scarlatiniform eruptions but is not completely reliable. Intradermal injections of a specific streptococcal antitoxin will cause blanching of the erythema in scarlet fever (Schultz-Charlton test), a test now very seldom used." Erythermalgia occurs in short attacks precipitated by heat which would seem to exclude it from the diagnosis Philip Bekhor Diane, I'm writing the next in the series of my Cutis articles on this very topic. Keratosis exfoliativa is corynebacterial, but it comes on in October and May more than any other months. SO deos herpses zoster. I have pondered this timing for 20 years. WHy? Maybe som one smart on the list knows the answer. As to erythromelalgia: I like Trental, DIltiazem, and a baby aspirin in combination. Of course, keeping warm is the best bet. Haines Ely I have treated several patients with erythromelalgia. Assuming a negative systemic workup, I have had success with combination therapy using beta blockers, trental and tricyclic antidepressants. This in patients who have failed aspirin therapy. Ethan D. Nydorf, M.D. I'd like to thank those who gave me advice on the young woman with erythromelalgia. I saw her back yesterday (after five days) and to my surprise she is symptom free on ASA 650 mgs qid. Feet no longer hot, slight erythema. Labs normal. I'm surprised this was so simple, but improvement may have nothing to do with medications. My second choice based on advice and readings would have been to add periactin. The suggestion of a localized scarletiniform eruption was interesting, and reaction to bacterial exotoxin similar to that seen with TSS and SSSS should have been considered. What I learned: 1) It's erythermalgia not erythromalgia 2) There's primary erythromelalgia, secondary erythromelalgia and erythermalgia. Much more complicated than I thought. Medline had 48 references in the past 3 years. David J. Elpern Erythromelalgia/erythermalgia Caper: In the Lancet, 1990: Vol 336, pp 183-4, JJ Michiels made the following observation: "The erythromelalgia patient finds: warmth intensifies discomfort a single dose of aspirin gives complete relief for several days the patient has a chronic myoproliferative disease with thrombocytopenia. platelet clumping leads to thrombi in the small vessels with resultant acrocyanosis and finally necrosis. "The erythermalgia patient experiences the same redness and burning pain of the extremities brought on by heat or exercise, but by contrast finds: no response to aspirin no progression to necrosis" The conclusion: "Watch your vowels or you'll get the diagnosis wrong. " See also JAAD 1989, Vol 21, pp 1128-30 on Idiopathic erythermalgia. Jerry Litt

47. Lessons From Erythromelalgia, Raynauds, RSD, Causalgia, Cluster Headaches For Fl
burning. This includes people with severe rosacea or facial erythromelalgia(EM). http Medicine, St. Louis, MO. erythromelalgia 5.
http://www.angelfire.com/journal2/sadhelp/emd.htm
EM Groups: EM best conceptualized as a neurovascular neuropathic pain condition? - New
http://www.erythromelalgia.org
- The Erythromelalgia Association (TEA) is an international nonprofit organization made up of people with erythromelalgia, or their family members, or friends. http://groups.yahoo.com/group/EM - This list was established (in January, 1999) to give people with erythromelalgia (aka "EM") a convenient way to communicate with each other about the disorder.
http://groups.yahoo.com/group/theredhots
- A support group for people who suffer from facial flushing or blushing, along with redness, pain and burning. This includes people with severe rosacea or facial Erythromelalgia (EM). http://groups.yahoo.com/group/rosacea-support - Rosacea Support Group Of Nearly 2000 Members. Page Bookmarks/Shortcuts: Neuropathies (EM/RSD) Outlines Pain Clinics other EM mentions CRPS-RSD/ ... http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaF/2.16.9911.21PMNewTreatmen.html - Below: http://neuro-www.mgh.harvard.edu/forum/ - Department of Neurology at Massachusetts General Hospital http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaMenu.html

48. Erythromelalgia PubMed Search
1) Facial erythromelalgia PubMed Search Bookmark Shortcuts 2 ) Facial ErythroprosopalgiaPubMed Search 3 ) General erythromelalgia /erythermalgia PubMed
http://www.angelfire.com/journal2/sadhelp/em.htm
1) Facial Erythromelalgia PubMed Search: Bookmark Shortcuts Facial Erythroprosopalgia PubMed Search: General Erythromelalgia /erythermalgia PubMed Search: Facial Erythromelalgia PubMed Search:
Itin PH, Courvoisier S, Stoll A, Battegay M. Related Articles
Secondary erythermalgia in an HIV-infected patient. Is there a pathogenic relationship?
Acta Derm Venereol. 1996 Jul;76(4):332-3. No abstract available.
PMID: 8869701 [PubMed - indexed for MEDLINE]
Drummond PD, Finch PM. Related Articles
Reflex control of facial flushing during body heating in man.
Brain. 1989 Oct;112 ( Pt 5):1351-8.
PMID: 2804616 [PubMed - indexed for MEDLINE]
Blanchet P. Related Articles
[Paroxystic vasomotor skin manifestations (author's transl)]
Ann Dermatol Venereol. 1978 Dec;105(12):1001-7. Review. French.
PMID: 88921 [PubMed - indexed for MEDLINE]
Regli F. Related Articles
[Facial neuralgia and vascular facial pain]
Praxis. 1969 Feb 18;58(7):210-5. German. No abstract available.

49. Health Library - Erythromelalgia
Advanced Search. erythromelalgia. Self Help Clearinghouse. TEA (Theerythromelalgia Association). National network. Founded
http://www.stjudemedicalcenter.org/Library/HealthGuide/SelfHelp/topic.asp?hwid=s

50. Health Library - Erythromelalgia
Advanced Search. erythromelalgia. erythromelalgia is a rare condition thatprimarily affects the feet and, less commonly, the hands (extremities).
http://www.stjudemedicalcenter.org/library/healthguide/IllnessConditions/topic.a

51. Health Library - Erythromelalgia
Events, SEARCH. erythromelalgia. Self Help Clearinghouse. TEA (Theerythromelalgia Association). National network. Founded
http://www.muskogeehealth.com/Library/HealthGuide/SelfHelp/topic.asp?hwid=shc29e

52. Health Library - Erythromelalgia
SEARCH. erythromelalgia. erythromelalgia is a rare condition that primarilyaffects the feet and, less commonly, the hands (extremities).
http://www.muskogeehealth.com/Library/HealthGuide/IllnessConditions/topic.asp?hw

53. Health Library - Erythromelalgia
Information, Advanced Search. erythromelalgia. Self Help Clearinghouse. TEA(The erythromelalgia Association). National network. Founded
http://www.sjo.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29ery

54. Health Library - Erythromelalgia
World class medicine. Hometown commitment. erythromelalgia. Self Help Clearinghouse.TEA (The erythromelalgia Association). National network.
http://www.phoebeputney.com/library/healthguide/SelfHelp/topic.asp?hwid=shc29ery

55. Health Library - Erythromelalgia
Hometown commitment. erythromelalgia. erythromelalgia is a rare condition thatprimarily affects the feet and, less commonly, the hands (extremities).
http://www.phoebeputney.com/library/healthguide/IllnessConditions/topic.asp?hwid

56. Health Library - Erythromelalgia
Affiliates. erythromelalgia. Self Help Clearinghouse. TEA (The erythromelalgiaAssociation). National network. Founded
http://www.danhosp.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29ery

57. Health Library - Erythromelalgia
Your Health, Advanced Search. erythromelalgia. Self Help Clearinghouse.TEA (The erythromelalgia Association). National network.
http://www.tetonhospital.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29er

58. Health Library - Erythromelalgia
Your Health, Advanced Search. erythromelalgia. erythromelalgia is a rare conditionthat primarily affects the feet and, less commonly, the hands (extremities).
http://www.tetonhospital.org/library/healthguide/IllnessConditions/topic.asp?hwi

59. Health Library - Erythromelalgia
HealthSource, erythromelalgia. Self Help Clearinghouse. TEA (The erythromelalgiaAssociation). National network. Founded
http://www.memorialhealthsource.com/library/healthguide/SelfHelp/topic.asp?hwid=

60. Health Library - Erythromelalgia
Physician Search Nursery Net Ways of Giving. erythromelalgia. Self Help Clearinghouse.TEA (The erythromelalgia Association). National network.
http://www.altru.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29ery

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