81. NIH News Release--Study Finds Hemochromatosis Patients' Blood Is As Safe As Othe Study Finds hemochromatosis Patients' Blood is as Safe as Other DonatedBlood May Help Alleviate Blood Shortage. Blood donors with http://www.nih.gov/news/pr/sep2001/nhlbi-25.htm

NATIONAL INSTITUTES OF HEALTH National Heart, Lung, and Blood Institute EMBARGOED FOR RELEASE Tuesday, September 25, 2001 4:00 p.m. EDT Contact: NHLBI Communications Office Study Finds Hemochromatosis Patients' Blood is as Safe as Other Donated Blood May Help Alleviate Blood Shortage Blood donors with hemochromatosis, a disorder in which iron accumulates in organs and body tissues, do not pose a greater risk to blood safety than other donors, according to the results of a study funded by the National Heart, Lung, and Blood Institute (NHLBI) and published in the September 26 issue of the Journal of the American Medical Association Hemochromatosis patients are treated with periodic phlebotomies or "blood letting" to remove excess iron from their body. Because these patients benefit medically and financially by giving blood (they don't have to pay for phlebotomy), there has been concern that they might donate despite having infectious disease risk factors and that their blood might be less safe. As a result, FDA regulations have not promoted blood donation from hemochromatosis patients. "Hemochromatosis patients in this study had no more risk of transmitting viral infections than did other donors. This finding should help guide future decisions on blood donations by these patients. If people with hemochromatosis qualify as donors then that could potentially have a significant impact on the national blood supply," said NHLBI Director Dr. Claude Lenfant.

82. MotherNature.com - Age Erasers For Women: Hemochromatosis Ch.36, Heart Disease. Ch.37, hemochromatosis. Ch.38, High Blood Pressure. Ch.39,Hysterectomy. Click Here To Learn More! hemochromatosis. Ironing Out the Problem. http://www.mothernature.com/Library/bookshelf/Books/44/37.cfm

Free Shipping on all orders over $35.00! Order By Phone 1-800-439-5506 (M-F 9-5 EST) Search Products Library 4 Ways To Shop Brands Gender/Age Health Concern Departments CHAPTER LIST FOR BOOK TITLE: Introduction to Age Erasers for Women Ch.1 Introduction to Age Erasers for Women Ch.2 Stop the Clock Ch.3 Age Spots Ch.4 Allergies Ch.5 Anger Ch.6 Arrhythmias Ch.7 Arthritis Ch.8 Back Pain Ch.9 Binge Eating Ch.10 Biological Clock Ch.11 Bladder Problems Ch.12 Body Image Ch.13 Burnout Ch.14 Bursitis and Tendinitis Ch.15 Caffeine Ch.16 Cancer Ch.17 Cellulite Ch.18 Cholesterol Ch.19 Dental Problems Ch.20 Depression Ch.21 Diabetes Ch.22 Dieting Ch.23 Digestive Problems Ch.24 Double Chin Ch.25 Drinking Problems Ch.26 Drug Dependency Ch.27 Eating Disorders Ch.28 Endometriosis Ch.29 Fatigue Ch.30 Fibroids Ch.31 Foot Problems Ch.32 Gray Hair Ch.33 Hair Loss Ch.34 Hearing Loss Ch.35 Heart Attack Ch.36 Heart Disease Ch.37 Hemochromatosis Ch.38 High Blood Pressure Ch.39 Hysterectomy Ch.40 Infertility Ch.41 Injuries and Accidents Ch.42

83. Hemochromatosis hemochromatosis. hemochromatosis is the 1 genetic killer in the US, affectingnearly two million Americans, yet most victims are unaware that they have it. http://members.aol.com/ThreePeb/hemochromatosis.html

Hemochromatosis Hemochromatosis is the #1 genetic killer in the U.S., affecting nearly two million Americans, yet most victims are unaware that they have it. Hemochromatosis is also very common in Europe and Western Africa. If left undetected and untreated, hemochromatosis is fatal in most cases. Hemochromatosis is an inherited disorder of the small intestine that causes a person to absorb too much iron from their food. Over time, iron builds to toxic levels and destroys many organs. Symptoms of toxic iron excess can differ greatly from person to person. Symptoms might include fatigue or depression, arthritis, impotence and infertility, diabetes, heart disease, and liver disease or liver cancer. Early detection and treatment will prevent iron excess and its toxic effects. Although hemochromatosis is widespread, the blood test for it, called a "Fasting Percent TIBC Saturation" (% TIBC SAT), is rarely included in general screenings. A 1994 study in the "Archives of Internal Medicine" showed the cost-effectiveness of the test "over a wide range" of conditions and recommended adding the test to routine blood screens. The test costs $40-$60 in most areas and is covered by many insurance plans. The Hemochromatosis Foundation is a nonprofit organization that has worked for nearly twenty years to improve the lives of people with hemochromatosis. For more information about the disease, screening events in your area, or how you can help in finding the cure for hemochromatosis, contact your local chapter, or write to:

84. Other Alopecias - Hemochromatosis keratin.com, hair loss, baldness, alopecia, disease, and treatment information.hemochromatosis. hemochromatosis. Hair loss can sometimes http://www.keratin.com/af/af008.shtml

hemochromatosis Home Forums Privacy Advertising ... Home On this page... Hemochromatosis Contact organization addresses Hemochromatosis Contact organization addresses American Hemochromatosis Society (AHS) 777 East Atlantic Avenue, Z-363 Delray Beach, FL 33483-5352 E-mail: ahs@emi.net Website: www.americanhs.org . The American Hemochromatosis Society (AHS) is dedicated to providing the latest information on genetic testing for hereditary hemochromatosis, pediatric hereditary hemochromatosis, and research relating to hereditary hemochromatosis/iron overload. They provide support for all individuals with iron overload. Hemochromatosis Research Foundation P.O. Box 8569 Albany, NY 12208 Tel: 518 489 0972 Fax: 518 489 0227 Navigation Hair Biology Diagnosis / Decisions Androgenetic Alopecia Alopecia Areata ... http://www.keratin.com/

85. Diseases And Conditions -- Discovery Health -- Hemochromatosis hemochromatosis is a genetic disorder that affects the way the body handlesiron. hemochromatosis By Ronald J. Jorgenson, DDS, PhD, FACMG. http://health.discovery.com/diseasesandcond/encyclopedia/672.html

hemochromatosis By Ronald J. Jorgenson, DDS, PhD, FACMG Hemochromatosis is a genetic disorder that affects the way the body handles iron. It causes iron to accumulate in the organs of affected people. The excessive iron causes the symptoms of the disorder. What is going on in the body? Everyone absorbs iron from the food they eat. In a person with hemochromatosis, too much iron is absorbed. The iron accumulates in organs such as the liver, heart, and pancreas. The overload of iron causes liver disease congestive heart failure , and diabetes What are the signs and symptoms of the disease? Hemochromatosis is characterized by: too much iron in the blood darkening of the skin cirrhosis of the liver. This condition involves changes in the liver in response to damage by excessive iron. liver cancer enlargement of the heart high blood sugar, caused by diabetes What are the causes and risks of the disease? Hemochromatosis is caused by a defective gene. The gene for hemocromatosis is recessive. This means a person must have two copies of this gene to have the disease. People with a single copy of the gene are called carriers. Carriers usually are not affected, although use of alcohol may cause symptoms to appear in them.

86. Hemochromatosis, University Of Pittsburgh Medical Center, Pittsburgh, PA, USA hemochromatosis, or iron overload, is caused by many different genetic or acquireddisorders that result in extra iron being deposited in organs and tissues. http://hemochromatosis.upmc.com/

Hemochromatosis, or iron overload, is caused by many different genetic or acquired disorders that result in extra iron being deposited in organs and tissues. When too much iron accumulates in tissues, the iron can damage the organs. Without treatment, the disease can cause organs to fail. Read more UPMC University of Pittsburgh Schools of the Health Sciences Contact UPMC Supplemental content provided by HealthGate Data Corp

87. Hemochromatosis MAIN SEARCH INDEX hemochromatosis. Definition. hemochromatosis is an inheritedblood disorder that causes the body to retain excessive amounts of iron. http://www.hendrickhealth.org/healthy/000646.htm

MAIN SEARCH INDEX Hemochromatosis Definition Description Causes and symptoms Diagnosis ... Resources Definition Hemochromatosis is an inherited blood disorder that causes the body to retain excessive amounts of iron. This iron overload can lead to serious health consequences, most notably cirrhosis of the liver. Description Hemochromatosis is also known as iron overload, bronze diabetes, hereditary hemochromatosis and familial hemochromatosis. The inherited disorder causes increased absorption of intestinal iron, well beyond that needed to replace the body's loss of iron. Iron overload diseases afflict as many as 1.5 million persons in the United States. The most common of these, as well as one of the most common genetic disorders in the United States, is hereditary hemochromatosis. Men and women are equally affected by hemochromatosis, but women are diagnosed later in life because of blood loss from menstruation and childbirth . It most commonly appears in patients between the ages of 40-60 years, since it takes many years for the body to accumulate excessive iron. Symptoms appear later in females than in males-usually after menopause Hemochromatosis causes excess iron storage in several organs of the body including the liver, pancreas, endocrine glands, heart, skin, joints, and intestinal lining. The buildup of iron in these organs can lead to serious complications, including

88. Hemochromatosis hemochromatosis. The hemochromatosis Foundation, Inc. hemochromatosisTesting information about iron overload and how to get tested. http://www.health-nexus.com/hemochromatosis11.htm

Health-Nexus.Net Health-Nexus.Org The #1 Health information site Home ... Up Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Hemochromatosis The Hemochromatosis Foundation, Inc. American Hemochromatosis Society Hemochromatosis Testing information about iron overload and how to get tested. Hereditary Hemochromatosis - The website of a family whose members have hemochromatosis, with a description of how they are affected, and links to hemochromatosis sites. - Iron Overload Disease Association Incorporated Charity And Non Profit Medical Association. Hemochromatosis DNA Testing at Kimball Genetics - Hemochromatosis DNA Test results in one day. Links on hemochromatosis - HEMOCHROMATOSIS LINKS FROM ALL OVER THE WORLD!

89. GastroIntestinal Specialists, AMC Located In Shreveport, Louisiana hemochromatosis What is hemochromatosis? hemochromatosis is a commondisorder of iron metabolism resulting in iron overload and http://www.gis.md/fact-hemochromatosis.html

Abdominal Pain Colorectal Cancer Constipation Food Intolerance ... Gastroesophageal Reflux Hemochromatosis Inflammatory Bowel Disease Intestinal Gas Irritable Bowel Syndrome Liver Disease ... Ulcer Disease Hemochromatosis What is hemochromatosis? Hemochromatosis is a common disorder of iron metabolism resulting in iron overload and affecting about 1 in 250 individuals of Northern European descent. It is an inherited disorder, but to actually develop problems from hemochromatosis you must inherit two abnormal genes, receiving one from each parent. If you have inherited both abnormal genes, you will absorb increased amounts of iron from your diet and will gradually accumulate excess iron, primarily in the liver. Over many years, these increased iron deposits in the liver can result in liver disease such as cirrhosis and cancer of the liver. What are the symptoms of hemochromatosis?

90. Hemochromatosis hemochromatosis. Definition hemochromatosis is an inherited blood disorderthat causes the body to retain excessive amounts of iron. http://www.chclibrary.org/micromed/00050600.html

Main Search Index Definition Description Causes ... Resources Hemochromatosis Definition Hemochromatosis is an inherited blood disorder that causes the body to retain excessive amounts of iron. This iron overload can lead to serious health consequences, most notably cirrhosis of the liver. Description Hemochromatosis causes excess iron storage in several organs of the body including the liver, pancreas, endocrine glands, heart, skin, and intestinal lining. The buildup of iron in these organs can lead to serious complications, including heart failure , liver cancer, andcirrhosis of the liver. It is estimated that about 5% of cirrhosis cases are caused by hereditary hemochromatosis. Idiopathic pulmonary hemosiderosis, a disorder afflicting children and young adults, is a similar overload disorder characterized by abnormal accumulation of hemosiderin. Hemosiderin is a protein found in most tissues, especially the liver. It is produced by digestion of hematin, an iron-related substance. Hereditary hemochromatosis is passed by an autosomal recessive trait on the genes. (Scientists have recently identified the precise gene.) Because of its hereditary nature, as many as 25% of the siblings of hemochromatosis patients will also develop the disorder.

91. The Genomics Revolution And Public Health hemochromatosis Case Study How genetics can improve health and preventdisease. Travis To learn more about hemochromatosis MEDLINEplus http://www.sph.unc.edu/nciph/phgenetics/hemochromatosis.htm

Home Why you should care about genetics A little knowledge Did you know? ... Resources and links Hemochromatosis Case Study How genetics can improve health and prevent disease Travis Hudson began having extreme pain in his ankle. Therapy did not help. Doctors could not pinpoint what was wrong with the ankle but thought it was probably arthritis. Hudson was scheduled for surgery to fuse his ankle. Then, one of his doctors found a test in his medical records showing a higher than normal level of iron in his blood. After some diagnostic tests and a gene test, Hudson was diagnosed with hereditary hemochromatosis, a disease of iron overload in body tissues. Complications from the condition can include joint problems, liver disease, heart problems, diabetes, impotence and infertility. In some cases untreated hemochromatosis can lead to early death. After hearing his diagnosis and reading information about hemochromatosis, Hudson thought he was doomed. However, his doctor assured him that hemochromatosis could be effectively treated by weekly phlebotomy (blood-letting) visits. Because Hudson was diagnosed and treated before many complications had set in, he can live a normal life. Hudson told his family about his hereditary condition and suggested they be tested for the gene, too. His sister and son were found to have the gene.

92. Effects Of Hemochromatosis revised February 4, 1999 Effects of Iron Overload. Hereditary hemochromatosis. Hereditaryhemochromatosis is the more common of the two by far. http://sickle.bwh.harvard.edu/hemochromatosis.html

93. AMNews: Sept. 25, 2000. Genetic Test For Hemochromatosis Debated ... American Me HEALTH SCIENCE. Genetic test for hemochromatosis debated. Many who work with hemochromatosispatients, however, are still advocating populationwide testing. http://www.ama-assn.org/sci-pubs/amnews/pick_00/hlsc0925.htm

@import url(http://www.ama-assn.org/sci-pubs/amnews/site/amnbasic.css); @import url(http://www.ama-assn.org/sci-pubs/amnews/site/amnprint.css) print; American Medical News LISTINGS '00 By date '00 By region Map '00 By health plan ... Search SERVICES Mobile edition E-mail alert Subscribe! Staff directory ... Send feedback ADVERTISEMENT Genetic test for hemochromatosis debated Study results show that a phenotype test alone does not always detect this blood disorder's genetic mutation. By Victoria Stagg Elliott AMNews staff. Sept. 25, 2000. Phenotypic tests for hemochromatosis fail to diagnose half the people who have the genetic mutation for the disorder because they do not have the characteristic high blood iron levels, according to a preliminary study published in the September Annals of Internal Medicine . The researchers also point out that there is no proof yet that all patients with the genetic mutation will develop the condition. "This seems to suggest [genetic testing] is going to be an overly sensitive way to pick up homozygotes for hemochromatosis," said Ernest Beutler, MD, chair of the department of molecular and experimental medicine at the Scripps Research Institute in California. He is also the primary author of the study. With this article Links The study, which looked at 10,000 patients in a large HMO in California and has, since publication, been expanded to 25,000, is the latest twist in the debate over how to deal with this iron overload disease linked to everything from arthritis to heart failure. Hemochromoatosis is easy to treat with periodic blood-letting, but doctors have always struggled to diagnose it.

94. Hemochromatosis Back Home Next. hemochromatosis Hereditary hemochromatosis. hemochromatosis.American hemochromatosis Society, Inc. Canadian hemochromatosis Society. http://www.ability.org.uk/Hemochromatosis.html

Our Aims Services Stats ... Z Hemochromatosis Hereditary Hemochromatosis Hemochromatosis American Hemochromatosis Society, Inc. MSU DNA Diagnostic Program ... Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

95. PBS - Who Cares: Chronic Illness In America -- James Hines James Hines Lancaster, MA I was diagnosed with hemochromatosis in1979. But my story pales in comparison to the many folks I have http://www.pbs.org/fredfriendly/whocares/your_stories/james_hines.html

James Hines Lancaster, MA I was diagnosed with Hemochromatosis in 1979. But my story pales in comparison to the many folks I have met on the Net who have been diagnosed with iron overloading from genetic Hemochromatosis. I believe the real story is why is it that so many people have to endure indignation, humiliation and rejection for as long as 3 - 5 years before getting a correct diagnosis. Oftentimes, it takes longer. The irony (no pun intended) is that the diagnosis requires nothing exceptional, merely available blood tests for excess iron and iron stores. The treatment is relatively simple and will prevent severe morbidity if diagnosed before the accumulated iron stores have had an opportunity to damage vital organs. As a community, we have nicknamed ourselves "Rusties" because of the joint deteriorate due to excess iron. In other words, many of joints are rusting out! Diagnosed early, with subsequent treatment consisting of frequent phlebotomies, an individual with Hemochromatosis can live a relative normal and productive life. I was diagnosed early as a result of an autopsy on my younger sister who died in 1975. The original autopsy identified "chronic alcoholism" as a contributor to my sister's death. But, my sister did not, nor could she, drink alcohol as just the odor of a single beer made her nauseous. When the pathologist revisited the autopsy, lo and behold, he located the real culprit iron. As a result, another sister and I were fortunate to get an early diagnosis.

96. Hemochromatosis Informs patients about hemochromatosis, an inborn error of iron metabolism,which can lead to liver cirrhosis, liver cancer and heart failure. http://www.ikp.unibe.ch/lab2/hemce.html

HEMOCHROMATOSIS Prof. Dr. med. J. Reichen Dept. of Clinical Pharmacology, University of Berne Deutsch, bitte 1. Prevalence and cause: Hemochromatosis is the most prevalent genetic disease of adults. One in 10 carries the faulty gene and 1/400 will get the disease. Based on this gene frequency we have to assume that in the Swiss population there are 17'500 - 20'000 patients affected. The main mutation in the gene, now called HFE, was described in 1996 by Feder and colleagues. The mutation leads to uncontrolled absorption of iron and deposition of this potentially toxic heavy metal in different organs. 2. What are the signs and symptoms? The first symptoms can originate from the liver, the articulations, the pancreas, the heart and endocrine glands. This first signs can be very subtle and the diagnosis is missed if the treating physician does not think about the possibility of hemochromatosis. Liver Fatigue, dull aches or pains in the upper belly Articulations Inflammation, pain and swelling Pancreas Diabetes (thirst, increased urination)

97. Dr. Rose's Peripheral Brain--HEMOCHROMATOSIS hemochromatosis. I. Pathophysiology abuse. Often get macrocytosis ( due toliver dysfunction ?); Genetic screens (for hereditary hemochromatosis). The http://faculty.washington.edu/momus/PB/hemochro.htm

HEMOCHROMATOSIS I. Pathophysiology Iron overload causing tissue damage Can be hereditary (mostly Caucasian), in which case excess intestinal absorption of iron occurs In the hereditary form, clinical manifestations occur after years of excess absorption Women homozygous for the hereditary defect express the disease 1/10 as often as men, prob. b/c of menstrual loss of iron Ethanol abuse or hepatitis accelerates liver and pancreatic damage, prob. due to high serum levels of ferritin after hepatocyte injury A candidate gene has been identified: HFEsee below Or secondary, caused by Chronic anemias, e.g. homozygous beta-thal Multiple transfusions Porphyria cutanea tarda Portocaval shunt, etc. Iron accumulation-ubiquitous, as ferritin and hemosiderin Liver All Fe absorbed from intestine passes through liver; any Fe that exceeds binding capacity of transferrin is deposited Pancreas, heart, gonads, thyroid, hypothalamus, pituitary, and joints, causing dysfunction in all these organs

98. Population Based Research For Hemochromatosis At Geneticepi hemochromatosis. hemochromatosis is a common recessive disorder inpopulations of caucasian origin. The disease is characterised http://www.geneticepi.com/Research/population/hemachromatosis/hemachromatosis.ht

Hemochromatosis We are studying the frequency, penetrance and clinical expression of the known HFE mutations through genotyping 3000 subjects participants in a population based study: The Rotterdam Study. The Rotterdam study is a population-based study of 7983 subjects aged 55 years and over. In this study, cardiovascular, neurological and endocrine disorders have been studied in relation to their genetic and non-genetic risk factors. We will thus assess: The mutation frequency of the C282Y and H63D in the elderly; The relationship of these mutations to the serum iron, ferritin and transferrin levels in homozygotes and heterozygotes; The relationship between these mutations and vascular pathologies (myocardial infarction, arythmias, atherosclerosis, lipid levels) neurological diseases (stroke, dementia), diabetes, bone disorders and mortality; The interaction between these common mutations and other genetic and non-genetic factors;

99. Hereditary Hemochromatosis Hereditary hemochromatosis Methods A MEDLINE search was performed usingmultiple key words related to hemochromatosis and iron metabolism. http://www.familypractice.com/journal/2001/v14.n04/1404.05/1404.05.htm

Hereditary Hemochromatosis Robert B. Hash, MD, Department of Family Medicine, Mercer University School of Medicine, Macon, Ga. [J Am Board Fam Pract 14(4):266-273, 2001. © 2001 American Board of Family Practice] Abstract Background: The understanding of hereditary hemochromatosis, along with the availability of genetic testing, is changing the approach to diagnosis of the disease. Methods: A MEDLINE search was performed using multiple key words related to hemochromatosis and iron metabolism. Results: Most cases of hereditary hemochromatosis are caused by a single mutation to the HFE gene, resulting in unregulated dietary iron uptake. The signs and symptoms of hereditary hemochromatosis are nonspecific and common in family practice settings. Measuring the transferrin saturation level is a cost-effective way to screen for suspected disease. Subsequent workup includes serum ferritin levels, hepatic enzyme levels, and HFE gene testing, or liver biopsy. HFE gene testing can provide a definitive diagnosis in many patients. Liver biopsy is useful and indicated when liver disease is clinically evident. Conclusion: For many patients, hereditary hemochromatosis can be diagnosed and treated in the physician's office. After iron mobilization with therapeutic phlebotomy, most patients will require phlebotomy 2 to 4 times each year throughout their lifetime. Treatment before organ toxicity occurs leads to a normal life span. Treatment after symptoms appear is less effective but can improve some signs and symptoms of iron toxicity.

100. Member Sign In Original Article hemochromatosis Clinical Implications from Medscape GeneralMedicine TM Posted 02/01/2002 Paul C. Adams, MD, Professor http://www.medscape.com/viewarticle/421519

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