61. Medichecks . Com - Show Test/Profile hughes syndrome (Sticky Blood / Lupus Anticoagulant). £ 116.00. Test Type Haematology. Contentshughes syndrome. Lupus Anticoagulant Anticardiolipin Antibodies. http://www.medichecks.com/test.cfm?test=LUPA-

62. Rev.pres.antiphospholipides.9904 hughes syndromeantiphospholipid antibodies move closer to thrombosis in 1994. http://www.paris-nord-sftg.com/rev.pres.antiphospholipides.9904.htm

accueil quoi de neuf? classement par spécialités cpte-rendus et doc de synthèse ... nous écrire syndrôme des antiphospholipides et avortements spontanés récurrents Traduit de: Editorials Antiphospholipid (Hughes') syndrome A treatable cause of recurrent pregnancy loss BMJ 1997;314:245 (25 January) CONSULTER L'ARTICLE ORIGINAL Voir également: thromboses veineuses SFTG Paris-Nord Quels droits pour ce document? Ce document appartient à la revue de presse de SFTG PARIS-NORD. Les documents de la revue de presse répondent aux normes suivantes: 1/ il s'agit de compte-rendus,brefs, ou de résumés d'articles. En aucun cas la revue de presse ne contient d'article reproduit in extenso 2/ la source documentaire est toujours indiquée, soit sous forme de la référence bibliographique, soit lorsque c'est possible, par un renvoi sur le site internet de la source documentaire. 3/ la source documentaire a été prévenue de la présence de ce document, par un courrier ou par un e-mail. 4/ les responsables de la source documentaire peuvent s'opposer à la présence de ce document: il sera immédiatement exclu du site de SFTG PARIS-NORD. Le syndrôme des antiphospholipides (syndrôme de Hugues), est une cause curable d'avortements à répétition. Décrite par Hugues en 83,elle est aujourd'hui reconnue comme une thrombophilie acquise associée à différents groupes d'anticorps. Ses traits caractéristiques principaux sont l'association de thromboses, à la fois veineuses et artérielles, d'une thrombocytopénie légère, de chorée, de maladies valvulaires, de livedo réticulaire, et, plus fréquemment, de fausses couches à répétition.

63. Bibliografia Tincani, hughes syndrome, antiphospholipid syndrome MA Khamashta(editor). hughes syndrome, a patient's guide Graham Hughes, The http://www.honegger.it/aps/bibliografia.htm

64. Ranvilles Infant School - 24 Hours A Day 7 Days A Week Aug 31Sep 6. hughes syndrome Awareness Week hughes syndrome Foundation020 7960 5561 fax 020 7633 0462 www.hughes-syndrome.org. Sept (tbc). http://www.hants.gov.uk/school/ranvilles/healthevents2003.htm

Ranvilles Infant School Oldbury Way, FAREHAM, Hampshire PO14 3BN Tel : 01329 841653 Fax : 01329 845754 Email : ranvillesinfants@hotmail.com Ranvilles Sitemap Health Events 2003 Jan 4-11 Arthritis Research Campaign Fax 01246 558007 www.arc.org.uk Jan 20-24 Allergy Uk Fax 020 8303 8792 www.allergyuk.org Jan 31 Bug Busting Day - Head Lice Beware Community Hygiene Concern Fax 020 7686 4322 www.nits.net/bugbusting Feb 1-28 Fax 01270 883 556 www.raynauds.demon.co.uk Feb 10-16 Contraceptive Awareness Week fpa (formerly Family Planning Association) fax 020 7837 6785 www.fpa.org.uk Feb 17 Hayfever Alert Day Allergy UK fax 020 8303 8792 www.allergyuk.org Feb 24-Mar 2 Brain Injury Awareness Week Headway - The Brain Injury Association fax 0115 958 4446 www.headway.org.uk Mar 8 United Nations fax 020 7976 6478 Mar 8 Marie Curie Daffodil Day Marie Curie Cancer Care Helpline fax 020 7599 7788 www.mariecurie.org.uk/daffodil Mar 12 No Smoking Day fax 0870 770 7910 www.nosmokingday.org.uk Mar 21 International Day for the Elimination of Racial Discrimination United Nations fax 020 7976 6478 www.un.org/events

65. Thromboses Veineuses Au Cours Du Lupus érythémateux Systémique Translate this page The antiphospholipid syndrome (hughes syndrome or antiphospholipid/cofactorssyndrome) is characterized by venous thromboses associated with the lupus http://www.medecine.uhp-nancy.fr/public/doc/Annales/01-98/article4.htm

Thromboses veineuses au cours du lupus érythémateux systémique Venous thrombosis in systemic lupus erythematosus D. WAHL, F. GUILLEMIN, E. de MAISTRE, C. PERRET-GUILLAUME, T. LECOMPTE, G. THIBAUT Résumé : Mots-clés : Thrombose veineuse profonde, embolie pulmonaire, anticorps antiphospholipides, syndrome de Hughes. Abstract : Venous thromboembolism (deep venous thrombosis and pulmonary embolism) is a frequent feature in systemic lupus erythematosus. The antiphospholipid syndrome (Hughes syndrome or antiphospholipid/cofactors syndrome) is characterized by venous thromboses associated with the lupus anticoagulant or anticardiolipin antibodies among other manifestations. However there are many other causes for venous thromboembolism in systemic lupus. Moreover the risk for venous thrombosis is higher in patients with the lupus anticoagulant (sixfold) than in patients with anticardiolipin antibodies (twofold). Numéro de Janvier 1998 - Article 4 - [ Table des matières Précédent Suivant

66. Autoimmune Links FRACP. HASHIMOTO'S DISEASE AARDA. hughes syndrome hughes syndrome Foundationsee also (Antiphospholipid Syndrome). IDIOPATHIC PULMONARY http://www.enetis.net/~rbreske/auto.htm

WELCOME HOME PAGE 1-MEDICAL LIN KS PAGE 2-MEDICAL LINKS ... E F G H I J K L M N O P Q R S T U V W X Y Z ADDISON'S DISEASE WEBMDHEALTH -Addison's Disease Symptoms AMERICAN AUTOIMMUNE RELATED DISEASES ASSOCIATION, INC. ALLERGIC AND IMMUNE DISORDERS OF THE LARYNX JAMES A. KOUFMAN, M.D. ANTIPHOSPHOLIPID ANTIBODY SYNDROME ANTIPHOSPHOLIPID ANTIBODY SYNDROME MEDICINE NET ARTHRITIS ABOUT.COM INTELIHEALTH UNIVERSITY OF WASHINGTON-Orthopaedic and Sports Medicine ARTHRITIS FOUNDATION ... INTELIHEALTH -Beat Arthritis Naturally HEALTHCENTRAL - Have Arthritis? Use Supplements Wisely HEALTHCENTRAL - Alternative Treatments No Cure For Arthritis ABC - Under the Weather - Biometeorology Connects Health and Weather REALAGE - Anti-Inflammatory Deemed Best for Arthritic Knees new MAYO CLINIC.COM -Nontraditional arthritis treatments: Some may help, but be wary MAYO CLINIC.COM -Arthritis: Protect your joints to prevent pain WEBMDHEALTH -Genes Play Minor Role in Arthritis WEBMDHEALTH -Chemotherapy for arthritis?

67. Antiphospholipid_Syndrome - HeartCenterOnline For Patients: Heart Health Encyclo Antiphospholipid Syndrome. (Anti Phospholipid Syndrome, APLS , LupusLikeSyndrome, APA, hughes syndrome, Anticardiolypin Antibody Syndrome). http://www.heartcenteronline.com/myheartdr/common/articles.cfm?ARTID=387

68. Immunologic Diseases The hughes syndrome ( Antiphospholipid Syndrome ) Foundation G Hughes;About Antiphospholipid Antibody Syndrome Univ of Illinois; http://www.mic.ki.se/Diseases/c20.html

search help staff Immunologic Diseases Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Alphabetical List of Diseases Search PubMed at NCBI/NLM Immonology Bowers et al. ; educ.] - Univ of South Carolina (US) A 4-pages introduction to The Immune System - Nobel Foundation About the Immune System - NCI/NIH (US) The Anatomy of the Immune System , and an Immunology Glossary - Univ of Leicester (UK) Basic Immunology G Heath ] - Optometry Today, Feb 2002 (UK) The Human Immune System K Bendtzen ] - Rigshospitalet (DK) Understanding the Immune System Schindler et al. ] - Cancer.gov (US) Immunobiology. 5th ed. Janeway et al. , 2001; online book] - via PubMed, NLM (US) The Immune System TJ Copeland An Immunology Study Sheet - Medical Study Guides, Univ of Kansas (US) How Your Immune System Works M Brain Immunobiology animations [Flash 5 Player required] - Garland Science Publ. (UK) Immunological Disorders Edgar and Sewell ; sample chapter] - Textbook of Medicine/Souhami et al.

69. Welcome To The Hughes Family Homepage This family tells about their homeschool and the challenges of raising a child with Down's syndrome. http://www.geocities.com/Heartland/Plains/5114/

We would like to take this opportunity to express our deepest sympathy to those who have been affected by the tragedy on September 11, 2001.  We ask you to pray for our president and those who will be making decisions in the days to come regarding what course of action this country will take.  We are so thankful for the firemen and the police who have been working around the clock in the clean-up effort. Please remember to thank those firemen and policemen in your local community who serve you and help to keep you safe. Let us draw together and stand in unity during this very difficult time. Welcome to the Hughes Family Homepage Please come in and visit... and won't you please sign our guestbook to let us know that you were here? Thanks for visiting! You are visitor # since 12-07-97 Thank you, Irene, for such beautiful graphics! All graphics on this page are by Graphics by Irene except the In Memory graphic which is from Mary's Little Lamb A big thanks to Mary for making it available!

70. The Antiphospholipid Syndrome (Hughes' Syndrome) The antiphospholipid syndrome (hughes' syndrome). Written by What is theantiphospholipid syndrome (hughes' syndrome)? The antiphospholipid http://www.netdoctor.co.uk/diseases/facts/antiphospholipid.htm

The UK's leading independent health website Search NetDoctor NetDoctor.co.uk Home News and features News Newsletter Features Encyclopaedia Diseases Medicines Examinations Health centres Cancer Children's health Depression Erectile dysfunction ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital NetDoctor on call Search Medline ... Text message services Information About NetDoctor Commercial opportunities NetDoctor.com The antiphospholipid syndrome (Hughes' syndrome) Written by Dr MY Karim , lecturer in immunology, St Thomas' Hospital and Dr GRV Hughes , consultant physician and rheumatologist, St Thomas' Hospital What is the antiphospholipid syndrome (Hughes' syndrome)? The antiphospholipid syndrome (APS) is sometimes called 'sticky blood syndrome'. This is because people with it have an increased tendency to form clots in blood vessels (also known as thromboses). Any blood vessel can be affected including the veins, which are thin walled and take blood towards the heart, and the arteries, which have thick muscular walls, and take blood away from the heart. As a result of this clotting tendency these patients may develop repeated clots, eg in the veins of the leg (deep vein thrombosis), or in the arteries supplying the brain, causing a stroke. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy. What is the cause of the antiphospholipid syndrome?

71. ALL HEALTH CENTRES Fibromyalgia); Gout (Podagra or uric acid); Heel pain and calcanealspurs; hughes' syndrome (Antiphospholipid syndrome); Inflammation http://www.netdoctor.co.uk/topic/index.asp?mode=Subject&SubjectId=21

72. Antiphospholipid (hughes') Syndrome ANTIPHOSPHOLIPID (hughes') syndrome 112 ANTIPHOSPHOLIPID (hughes) syndrome A treatable cause of recurrent pregnancy loss. This syndrome was first described by hughes in 1983. http://www.healthlibrary.com/reading/pointers/jan97/antiph.htm

ANTIPHOSPHOLIPID (HUGHES') SYNDROME A treatable cause of recurrent pregnancy loss. This syndrome was first described by Hughes in 1983. It is an important cause of thrombotic disease, both venous and arterial (especially recurrent cerebral ischemic attacks). Other features include mild thrombocytopenia, chorea, heart valve disease, livedo reticularis, and most commonly, recurrent pregnancy loss. It is due to an autoantibody directed against phospholipids. It was first described in patients with systemic lupus erythematosis, but most patients with the syndrome do not have lupus. The importance of the syndrome in general medicine, especially in vascular and neurological disease, is now acknowledged. BMJ January 25, 1997; 253: 253-57 . A treatable cause of recurrent pregnancy loss. This syndrome was first described by Hughes in 1983. It is an important cause of thrombotic disease, both venous and arterial (especially recurrent cerebral ischemic attacks). Other features include mild thrombocytopenia, chorea, heart valve disease, livedo reticularis, and most commonly, recurrent pregnancy loss. It is due to an autoantibody directed against phospholipids. It was first described in patients with systemic lupus erythematosis, but most patients with the syndrome do not have lupus. The importance of the syndrome in general medicine, especially in vascular and neurological disease, is now acknowledged.

73. Hughes' Syndrome hughes' syndrome The antiphospholipid syndrome. A historical view.Dr The primary antiphospholipid syndrome (hughes' syndrome). We http://www.infotech.demon.co.uk/APS2.htm

Hughes' Syndrome: The antiphospholipid syndrome. A historical view Dr. Graham R.V. Hughes, MD FRCP The Rayne Institute St. Thomas' Hospital, London, UK. (First printed in Lupus: An International Journal, Volume 7 Supplement 2: 8th International Symposium on Antiphospholipid Antibodies. Sapporo, Japan, 6-9 October 1998.) (Full references have been omitted and the reader should refer to the above journal or to Stockton Press Introduction In 1983 we described a complex clinical syndrome, characterised by thrombosis, recurrent abortion, neurological disease and anti-phospholipid antibodies. In the 1983 "Prosser-White Oration" to the British Society of Dermatology, the following passages still seem clinically appropriate 15 years later: "Although many of these patients fall under the general heading of lupus, or lupus-like disease, I believe that the group is sufficiently homogenous and in some ways (such as the frequently negative ANA serology) sufficiently different from typical systemic lupus erythematosus (SLE) to warrant separate consideration. the manifestations of this syndrome are thrombosis (often multiple) and frequently, spontaneous abortions (often multiple), neurological disease, thrombocytopenia and livedo reticularis. The livedo reticularis is often florid on the knees. This may or may not be associated with mild to moderate Raynaud's phenomenon. These patients' blood pressures often fluctuate, apparently correlating with the severity of the livedo, suggesting a possible reno-vascular aetiology. However, this group of patients rarely has primary renal disease.

74. Lupus UK Factsheet 18 - Lupus And Associated Conditions Lupus and Associated Conditions. Back to Lupus Information. hughes'syndrome (antiphospholipid syndrome). This is often called “sticky http://www.kitzbuhel.demon.co.uk/lupus/faqshets/faqs18.htm

Lupus and Associated Conditions Back to Lupus Information Hughes' syndrome (antiphospholipid syndrome) This is often called “sticky blood” in that the patients have a tendency to clots both in the veins and arteries. The thrombosis may present either dramatically or over a period of time with clots in major vessels, even including the brain. It is vital that this diagnosis is made (a simple blood test for antiphospholipid antibodies is available in most major hospitals). Pregnant women who have antiphospholipid antibodies have a tendency to clot the placenta and develop recurrent miscarriages and these can be prevented by diagnosis and treatment. Although this syndrome was first discovered in lupus patients it is now recognised that many, if not the majority, of patients with Hughes’ syndrome have no other features of lupus nor will they develop lupus in the future. Sjögren's syndrome ... Back to Lupus Information

75. Hughes's Syndrome - General Practice Notebook medical information from General Practice Notebook. hughes's syndrome.This syndrome was first described in 19831986 as the association http://www.gpnotebook.co.uk/cache/-1966079921.htm

Hughes's syndrome This syndrome was first described in 1983-1986 as the association of arterial and venous thrombosis with antibodies directed against phospholipids. Originally noted as a complication in approximately 30% of patients with systemic lupus erythematosus, it is now also diagnosed in patients with thrombotic episodes and anti-phospholipid antibodies (aPL) but without clinical features of SLE - primary antiphospholipid syndrome. Click here for more information...

76. MARRTC: Lupus-like Disease Causes Miscarriages, Strokes expert on lupus, ran tests and found she also had antiphospholipid antibodies, anindicator of what would be later called hughes' syndrome, or sticky blood http://www.muhealth.org/~arthritis/articles/jan00/stickyblood.html

Conditions General Arthritis Rheumatoid Arthritis Osteoarthritis Juvenile Arthritis Fibromyalgia Osteoporosis Lupus Wegener's Other... Missouri Calendar Arthritis Program Regional Cntrs JA Program MARRTC About Us Spotlight Publications Contact Us You are here: Home Sticky Blood Lupus-like Disease Causes Miscarriages, Strokes By Dianna Borsi O'Brien (Columbia, Mo.; January 16, 2000) Graham Hughes, an expert on lupus, recalls a patient he saw several years ago. Confined to a wheelchair, she was completely paralyzed from a blood clotting disorder that clogged her veins, causing paralysis, bladder disease, and multiple miscarriages. Hughes, an international expert on lupus, ran tests and found she also had antiphospholipid antibodies, an indicator of what would be later called "Hughes' Syndrome," or "sticky blood " as it is known in his native United Kingdom. Today, the once seriously ill woman lives a full and normal life, working as a secretary, freed of the paralyzing effects of the disorder. Hughes spoke on Thursday, Nov. 11, 1999, at the 23rd annual Michael Einbender Distinguished Lectureship in Medical Research of Lupus at the University of Missouri's Health Sciences Center.

77. Maryland Lupus Foundation, Inc. antiphospholipid syndrome. At the fifth international meeting on the syndrome inLeuven in 1995, a number of colleagues renamed the disease hughes' syndrome. http://131.103.214.192/lupusmd/doc_009.asp

78. Bmj.com Khamashta And Mackworth-Young 314 (7076): 245 Similar pages Barcelona, Spain, March 25th to 27th 2001 of the main stimuli to the more discriminating use of steroids came from the description,in 1983, of the antiphospholipid syndrome (APS) (hughes' syndrome). http://www.bmj.com/cgi/content/full/314/7076/245

Home Help Search/Archive Feedback ... Respond to this article Related letters in BMJ PubMed citation Related articles in PubMed Download to Citation Manager This article has been cited by other articles Search Medline for articles by: Khamashta, M. A Mackworth-Young, C. Alert me when: New articles cite this article BMJ Editorials Antiphospholipid (Hughes') syndrome A treatable cause of recurrent pregnancy loss The antiphospholipid syndrome, first described in 1983, is now recognised as an important prothrombotic disorder associated with a specific group of antibodies. Its main clinical feature is thrombosis, both venous and arterial (especially recurrent cerebral ischaemic attacks). Other features include mild thrombocytopenia, chorea, heart valve disease, livedo reticularis, and, most commonly, recurrent pregnancy loss. The importance of the syndrome in general medicine, especially in vascular and neurological disease, is now acknowledged. The syndrome has had various names. Hughes originally studied it in patients with systemic lupus erythematosus but recognised the concept of "primary" antiphospholipid syndrome.

79. Hughes' Guide For The Patient hughes' syndrome. A Patient's Guide to the Antiphospholipid syndrome. Diagnosingand managing hughes' syndrome has proved exciting and satisfying. http://www.angelfire.com/sd/APS/Hughesguide.html

Hughes' Syndrome A Patient's Guide to the Antiphospholipid Syndrome Dr Graham Hughes Preface In 1983 and during the following two years, the Lupus Research Unit at St Thomas published a number of papers showing that certain blood proteins (antiphospholipid antibodies) were associated with a syndrome of clotting (thrombosis), recurrent miscarriages and brain disease. Between 1983 and 1985, a comprehensive clinical/laboratory profile was presented showing, for the first time, a wide spectrum of clinical features including the association with artery thrombosis (including major organs such as kidney and liver), brain disease (strokes and other features), skin rashes, low platelet counts, epilepsy and migraine. These features could and frequently did occur in the absence of lupus, leading to the term primary antiphospholipid syndrome . Laboratory assays were set up, and we instituted standardisation workshops and organised the first and second International Congresses on the subject. The seventh was held in 1996. Diagnosing and managing Hughes' Syndrome has proved exciting and satisfying. For example, the success rate in pregnancy alone has risen from under 20% to over 70%.

80. Sindrome Da Anticorpi Antifosfolipidi Fornisce informazioni sulle caratteristiche e sulla storia della sindrome da anticorpi antifosfolipidi Category World Italiano Salute Malattie...... hughes' syndrome ) is typically associatedwith thrombosis, low platelet count or fetal losses and sometimes with http://www.angelfire.com/sd/APS/

Sindrome da Anticorpi Antifosfolipidi La Sindrome da Antifosfolipidi, anche nota come sindrome di Hughes , è un disordine autoimmune caratterizzato da trombosi piastrinopenia aborti ricorrenti (occasionalmente problemi neurologici cutanei cardiaci ) e da autoanticorpi specifici. 10° Simposio Internazionale sugli anticorpi antifosfolipidi 29 settembre - 3 ottobre 2002 Giardini Naxos, Taormina Può manifestarsi in corso di altre malattie autoimmuni APS secondaria ) o in forma primitiva The Antiphospholipid Antibody Syndrome Hughes' syndrome ") is typically associated with thrombosis low platelet count or fetal losses and sometimes with neurologic symptoms, valvular or cutaneous abnormalities . It is also characterized by elevated levels of specific autoantibodies (*) Livelli anomali di anticorpi antifosfolipidi possono essere rilevati in persone sane, che non necessariamente svilupperanno sintomi. (*) Il Lupus Anticoagulante è solo un test di laboratorio e non sinonimo di Lupus Sistemico (altra patologia autoimmune). aps@email.it

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