41. Hyperparathyroidism Primary hyperparathyroidism is characterized by an overproduction of parathyroidhormone, which, in turn, results in an elevation of calcium levels in the blood http://www.healthandage.com/html/res/com/ConsConditions/HyperparathyroidismPrima

Table of Contents Conditions Hyperparathyroidism Also Listed As: Signs and Symptoms What Causes It? Who's Most At Risk? What to Expect at Your Provider's Office ... Supporting Research There are four parathyroid glands, located behind the two lobes of the thyroid gland. The parathyroid glands produce the hormone that regulates blood levels of calcium and phosphate, minerals necessary for strong bones and teeth. Primary hyperparathyroidism is characterized by an overproduction of parathyroid hormone, which, in turn, results in an elevation of calcium levels in the blood. Signs and Symptoms At least 50% of patients with primary hyperparathyroidism have no symptoms, and approximately 1% of cases go undiagnosed. When symptoms do occur, they are generally attributable to persistently high levels of calcium and may include: Joint pain  Bone loss leading to osteoporosis Muscle weakness  Abdominal discomfort  Heartburn Nausea and vomiting Constipation  Lack of appetite  Ulcers Pancreatitis (inflammation of the pancreas)  Kidney stones Excessive thirst Excessive urination  Depression Anxiety  Memory loss  Excessive drowsiness  What Causes It?

42. Hyperparathyroidism hyperparathyroidism,, Print this article, The clinical features of primaryand secondary hyperparathyroidism differ in some respects (Table 1). http://www.amershamhealth.com/medcyclopaedia/Volume III 1/hyperparathyroidism.ht

Medcyclopaedia About Medcyclopaedia Amersham Health Search for: Type a word or a phrase. All forms of the word are searchable. Advanced search Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search *For Medical Professionals only, registration required Hyperparathyroidism, a condition in which increased levels of parathyroid hormone are found in the blood. Three types are recognized: primary, secondary and tertiary. In the primary form increased parathyroid hormone secretion occurs as a result of abnormality in one or more of the parathyroid glands, usually owing to the presence of adenoma or carcinoma. In this form the fundamental biochemical finding is persistent hypercalcaemia . The secondary form is associated with abnormalities of parathyroid gland function induced by a sustained hypocalcaemic stimulus, often resulting from chronic renal failure or malabsorption states. In this variety, renal abnormality is associated with additional soft tissue and skeletal changes, and the entire complex is termed renal osteodystrophy . Tertiary hyperparathyroidism is found in patients with chronic renal failure or malabsorption and secondary hyperparathyroidism of long duration who develop relatively autonomous parathyroid function and hypercalcaemia. The clinical features of primary and secondary hyperparathyroidism differ in some respects (Table 1).

43. M. D. Anderson Cancer Center - Endocrine Neoplasia & Hormonal Disorders the adrenal glands; hyperparathyroidism and parathyroid tumors; Pituitaryadenomas; Pancreatic islet cell tumors; Multiple endocrine http://www.mdanderson.org/departments/endocrinology/

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44. Hyperparathyroidism hyperparathyroidism. Introduction. Under The most frequent cause of hypercalcemiain the United States today is hyperparathyroidism. An http://www.surgeryoftheneck.com/hyperp.htm

Hyperparathyroidism Introduction U nder normal circumstances, the blood calcium is kept within the normal range by a hormone from the parathyroid glands. There are usually four parathyroid glands (two on either side of the neck) located on the posterior aspect of the thyroid gland. The main action of parathyroid hormone (PTH) is to raise the calcium blood level by releasing calcium from the bones. Parathormone also increases the absorption of calcium through the intestinal tract and effects the amount of calcium excreted through the urine, but these are secondary functions compared to the effect on the bones. The release of PTH is controlled by the serum calcium level. When the serum calcium level falls, the PTH level rises, which, in turn releases calcium from the bones to maintain the normal blood calcium level. When the calcium blood level is elevated, the parathormorne level should be low. The most frequent cause of hypercalcemia in the United States today is hyperparathyroidism. An estimated 100,000 new cases of hyperparathyroidism are seen in this country each year. This condition occurs 3-4 times more often in females than males and increases with age. Diagnosis Today most patients with primary hyperparathyroidism are identified incidentally by a multi-channel chemical blood analysis. Symptomatology of primary hyperparathyroidism includes the five classical groups of symptoms; painful bones, kidney stones, abnormal groans, psychic moans, and fatigue overtones. Table 1 shows frequency of different symptomatology. The diagnosis of primary hyperparathyroidism depends upon; 1) repeated documentation of hypercalcemia, 2) the exclusion of external causes of hypercalcemia, (such as high doses of vitamins A or D or large amounts of calcium containing substances, 3) normal kidney function, 4) the exclusion of malignancy, and 5) parathormone (PTH) assay levels appropriately elevated in relation to concurrently determined serum calcium.

45. NDI Terminology - Hyperparathyroidism hyperparathyroidism. DEFINITION Definition has yet to be entered. Checkback later. The definitions used in this glossary of terminology http://www.ndif.org/Terms/hyperparathyroidism.html

hyperparathyroidism DEFINITION: Definition has yet to be entered. Check back later. The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine , Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Dorland's Illustrated Medical Dictionary , 28th Edition, W. B. Saunders Company, Philadelphia, 1994; The Random House Dictionary of the English Language , Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary TERMINOLOGY WHERE THIS WORD IS USED TABLE of CONTENTS INFO. REQUEST ENTRANCE

46. NPS - Therapeutic Areas: Hyperparathyroidism drug development therapeutic areas hyperparathyroidism, hyperparathyroidism.Approximately one million people in the United States http://www.npsp.com/drug_development/ta_hpt.php

Hyperparathyroidism Approximately one million people in the United States suffer from one of two forms of hyperparathyroidism (HPT). This condition results from oversecretion of parathyroid hormone (PTH) by the parathyroid glands. Primary HPT predominately affects postmenopausal women. Secondary HPT afflicts the vast majority of kidney dialysis patients. Primary HPT Calcimimetics may be the first safe and effective drug therapy for controlling both primary and secondary HPT. Secondary HPT scientific publications Pharmacological regulation of parathyroid hormone secretion. Calcimimetic Compounds The first safe and effective drug therapy for controlling both primary and secondary HPT may be provided by a class of orally active, small molecules known as calcimimetics , which were discovered by NPS Pharmaceuticals. These compounds act at calcium receptors on the surface of parathyroid cells that are known to exert direct control on the secretion of PTH. (Calcium receptors were first cloned in 1993 by NPS scientists and their collaborators at the Brigham and Women's Hospital in Boston .) In animal models and human clinical trials, calcimimetic drugs have demonstrated the ability to rapidly and significantly lower PTH levels in both primary and secondary HPT.

47. AYC: Hyperparathyroidism hyperparathyroidism Basic Information. hyperparathyroidism is an overactivity of the parathyroid glands the four small glands http://alwaysyourchoice.com/ayc/adult/general/hparat.php

Adult Medicine General Health Acne Acute Lymphocytic Leukemia ... Information Hyperparathyroidism Basic Information Women are more likely to have hyperparathyroidism than men it occurs most frequently in postmenopausal women with approximately one case in one thousand. Those most at risk are: females (especially postmenopausal) patients of increased age, especially over 50 patients with a history of the disease in the family patients with Vitamin D deficiency patients with recent illnesses such as endocrine disorders Left untreated there can be serious complications including: kidney damage cataracts peptic ulcer pancreatitis It is wise to provide a copy of your previous medical records to your current health care provider so that he or she can see when your blood calcium first became elevated. Symptoms Patients with this condition are asymptomatic in 50% of cases. It is often discovered "out of the blue" by your health care provider during a routine blood test.

48. Wheeless' Textbook Of Orthopaedics Main Menu Home Page hyperparathyroidism Primary hyperparathyroidism changingpatterns in presentation and treatment decisions in the eighties. Rao DS. http://www.ortho-u.net/05/304.htm

Main Menu Home Page Hyperparathyroidism: - See: - Renal Osteodystrophy Remodeling of Bone - Discussion: - a disorder which is caused by excessive production of parathyroid hormone which leads to hypercalcemia causes: - in most cases is due to single parathyroid adenoma (80% of patients); - malignant tumor: occurs in about 1% of patients with hyperparathyroidism; - occurs often in association w/ multiple endocrine neoplasia syndrome, and rarely to parathyroid carcinoma; - hyperparathyoidism is sometimes seen in renal cell carcinoma and squamous cell carcinoma; - diff dx : - occult tumor; - multiple myeloma (often associated w/ hypercalcemia); - classification: - primary defect of the parathyroid gland w/ hypersecretion of PTH as seen w/ adenoma's of the parathyroid gland; - secondaray causes arise from conditions that produces abnormally low ionic plasma Ca levels and thereby stimulates production of PTH (see renal disease: effects on bone ): - tertiary conditions in which PTH secretion has become autonomous after prolonged stimulation of gland owing to secondary parathyroidism; - references: - Primary hyperparathyroidism: incidence, morbidity, and potential economic impact in a community. Heath H III, Hodgson SF, Kennedy MA. N Engl J Med 1980;302:189-93. - Pathology of the parathyroids in hyperparathyroidism: discussion of recent advances in the anatomy and pathology of the parathyroid glands. Roth SI. Arch Pathol 1962;73:495-510. - Recent advances in parathyroid gland pathology. Roth SI. Am J Med 1971;50:612-22. - Primary hyperparathyroidism: changing patterns in presentation and treatment decisions in the eighties. Rao DS. Henry Ford Hosp Med J 1985;33:194-7.

49. Medstar Health - Medical Matters 01/12/02 New Surgical Treatment for hyperparathyroidism. 12/29/01 - HealthyNew Year's Resolutions. New Surgical Treatment for hyperparathyroidism . http://www.medstarhealth.org/medicalmatters/week69.cfm

Medical Matters Home 08/17/02 - In vitro Fertilization 08/10/02 - Back Pain 08/03/02 - Advances in Knee Replacement Surgery ... 7/15/00 - Advances in Skin Cancer Vaccine Research "New Surgical Treatment for Hyperparathyroidism" Saturday, January 12, 2002 Dr. John Zapas Surgical Oncology Franklin Square Hospital Center For more information about hyperparathyroidism, call the Franklin Square Hospital Center at 443-777-7900. New Surgical Treatment for Hyperparathyroidism Hyperparathyroidism is a hormonal condition that causes an excess of the parathyroid hormone, resulting in increased calcium levels in the blood. This condition, while showing few obvious symptoms, can put a person at a severe risk for bone loss if left untreated. Patients - typically women 50 to 60 - also can develop kidney stones, muscle weakness, fatigue and/or depression. Doctors are Franklin Square Hospital Center are utilizing a new surgical technique. The standard method to treat this condition has been to undergo a procedure that requires the patient to undergo general anesthesia while a large incision is made in the neck. Now, surgeons use a minimally invasive procedure to locate the tumor under local anesthesia. Instead of a two-day recovery n the hospital, patients goes home the same day. For more information, please call Franklin Square Hospital Center at 443-777-7900.

50. Health Ency.: Disease: Hyperparathyroidism hyperparathyroidism. http://www.austin360.com/shared/health/adam/ency/article/001215.html

SEARCH: The Web Yellow Pages HOME Illustrated Health Encyclopedia Important notice Ency. home Disease H Hyperparathyroidism Overview Symptoms Treatment Prevention Definition: Excessive production of parathyroid hormone by the parathyroid glands. Causes and Risks Hyperparathyroidism can be caused by enlargement of one or more of the parathyroid glands or in response to abnormally low calcium levels in the blood. The parathyroid glands are located at the front and base of the neck around the thyroid gland and produce parathyroid hormone . Parathyroid hormone regulates calcium, phosphorus, and magnesium balance within the blood and bone by maintaining a balance between the mineral levels in the blood and the bone. Excessive levels of parathyroid hormone disturbs this balance and results in increasing the blood calcium level by reabsorbing it from the bone and increasing absorption from the kidneys and intestines. The effects of abnormal calcium levels are seen in several body systems including the skeletal, gastrointestinal, renal , muscular, and central nervous system Related topics: Parathyroid related hypercalcemia Primary hyperparathyroidism Secondary hyperparathyroidism Tertiary hyperparathyroidism Ency. home

51. Hyperparathyroidism About Table of Contents Metabolic Bone Disease Help hyperparathyroidism. hyperparathyroidismmay be either primary, secondary or tertiary. Primary. http://imc.gsm.com/integrated/msk/mspath/enneking/sect07/hypara.html

About Table of Contents Metabolic Bone Disease Help Hyperparathyroidism Introduction Primary Secondary Tertiary ... Self-evaluation Introduction Metabolic bone disease can result from either primary disorders of the endocrine system or, more commonly, from the reaction of the endocrine system to abnormalities in other organ systems. Although all of the endocrine organs have an effect on bone metabolism, disorders related to parathyroid gland function present the most common and significant problems. Hyperparathyroidism may be either primary, secondary or tertiary. Primary Primary hyperparathyroidism results from a parathyroid tumor (benign or malignant) with uncontrolled ectopic production of parathyroid hormone (PTH) by the chief cells. This anomaly may be part of multiple endocrine dysfunction syndromes. The effect of elevated PTH on the target organs results in increased serum calcium, alkaline phosphatase, and PTH but decreased serum phosphate. The presence of systemic symptoms is related to the level of hypercalcemia. Secondary Secondary hyperparathyroidism, which is most commonly associated with renal disease, results from chronic

52. Primary Hyperparathyroidism Hypercalcemia with emphasis on hyperparathyroidism. Differential Diagnosisof Hypercalcemia Parathyroidrelated -Primary hyperparathyroidism http://www.siumed.edu/surgery/otol/hyperparathyroid.html

Hypercalcemia with emphasis on Hyperparathyroidism Differential Diagnosis of Hypercalcemia: Parathyroid-related -Primary Hyperparathyroidism a. Solitary Adenoma b. MEN -Lithium therapy -Familial Hypocalciuric hypercalcemia Malignancy Related -Solid Tumor with Mets -Solid tumor with Humoral mediation (Lung,Kidney) -Hematologic malignancies (MM,Lymphoma,Leukemia) Vitamin D-related -vit D toxicity -Elevated 1,25(OH)D Sarcoidosis and other Granulomatous disease -Idiopathic Hypercalcemia of infancy High bone turnover -Hyperthyroidism -Immobilization -Thiazides -Vitamin A intoxication Associated with renal failure -Severe secondary hyperparathyroidism -Aluminium intox. -Milk-alkali syndrome Primary Hyperparathyroidism Definition : generalized disorder of calcium, phosphate, and bone metabolism due to an increase secretion of parathyroid hormone. The elevation of circulating hormone usually leads to hypercalcemia and hypophosphatemia. Incidence : .2% in patients over age 60, estimated prevalence of 1%.. Peak incidence is between the third and fifty decades but occurs in young children and in the elderly

53. PARATHYROID (HYPERPARATHYROIDISM) PARATHYROID (hyperparathyroidism). Effect of hormone replacement therapy on bone mineraldensity in postmenopausal women with mild primary hyperparathyroidism. http://www.lef.org/protocols/abstracts/abstr-087.html

LEF Site Search All categories Protocols Health Conditions Products LE Magazine Medical Abstracts What's Hot FDA Information About LEF LEF News Research Health Concerns Funded Research Track Record Innovative Doctors ... Scientific Advisory Free Product Directory Click for a FREE copy of our Product Directory LEF Membership What is LEF? Benefits Become a Member Renewals ... Become a Subscriber Our call center has now expanded its hours Monday thru Friday: 8:30am to 12:00am EST 5:30am to 9:00pm PST Saturday hours are: 9:00am to 8:00pm EST 6:00am to 5:00pm PST Sunday hours are: 11:00am to 7:00pm EST 8:00am to 4:00pm PST If you'd like to order by phone or speak to a live person for help, just call toll free: Customer Service Info Privacy Policy We subscribe to the HONcode principles. Verify here PARATHYROID (HYPERPARATHYROIDISM) Printing? Use This! Vitamin D3 and calcium to prevent hip fractures in the elderly women. Effect of hormone replacement therapy on bone mineral density in postmenopausal women with mild primary hyperparathyroidism. A randomized, controlled trial. Hyperparathyroidism. ... Comparison of effects of calcitriol and calcium carbonate on secretion of interleukin-1beta and tumour necrosis factor-alpha by uraemic peripheral blood mononuclear cells Vitamin D3 and calcium to prevent hip fractures in the elderly women.

54. PARATHYROID (Hyperparathyroidism) - Disease Therapies Protocol Verify here. PARATHYROID (hyperparathyroidism). Disclaimer Abstracts forProtocol Printing? Use this ! image hyperparathyroidism Overactivity. http://www.lef.org/protocols/prtcl-087.shtml

LEF Site Search All categories Protocols Health Conditions Products LE Magazine Medical Abstracts What's Hot FDA Information About LEF LEF News Research Health Concerns Funded Research Track Record Innovative Doctors ... Scientific Advisory Free Product Directory Click for a FREE copy of our Product Directory LEF Membership What is LEF? Benefits Become a Member Renewals ... Become a Subscriber Our call center has now expanded its hours Monday thru Friday: 8:30am to 12:00am EST 5:30am to 9:00pm PST Saturday hours are: 9:00am to 8:00pm EST 6:00am to 5:00pm PST Sunday hours are: 11:00am to 7:00pm EST 8:00am to 4:00pm PST If you'd like to order by phone or speak to a live person for help, just call toll free: Customer Service Info Privacy Policy We subscribe to the HONcode principles. Verify here PARATHYROID (Hyperparathyroidism) Abstracts for Protocol Printing? Use this ! Related Products MINERAL FORMULA FOR WOMEN 100 CA...

55. Online Health Analysis: Conditions: Hyperparathyroidism This enlargement of one parathyroid gland is called a parathyroid adenoma whichaccounts for 8793% of all patients with primary hyperparathyroidism. http://www.digitalnaturopath.com/cond/C651681.html

Hyperparathyroidism Last updated: Jan 28, 2003 THE ANALYST TM Home FAQ Start The Analyst Hyperparathyroidism Signs, symptoms and indicators Conditions that suggest it Contributing risk factors It can lead to... ... Recommendations The primary disease of parathyroid glands is overactivity, with too much parathyroid hormone (PTH) being produced. In this condition, one or more of the parathyroid glands behaves inappropriately by making excess hormone regardless of the level of calcium . In other words, the parathyroid glands continue to make large amounts of parathyroid hormone even when the calcium level is normal and they should not be making hormone at all. The most common cause of excess hormone production is the development of a benign tumor in one of the parathyroid glands. This enlargement of one parathyroid gland is called a parathyroid adenoma which accounts for 87-93% of all patients with primary hyperparathyroidism. Typically, one of the parathyroid glands has developed a tumor which is secreting all the hormone . The other three glands are small and responding appropriately to the high calcium by becoming dormant. This out of control

56. Bone Disorders - Primary Hyperparathyroidism These glands are responsible for calcium regulation. What is primaryhyperparathyroidism? What causes primary hyperparathyroidism? http://www.baptistoneword.org/healthinfo/bone Folder/hyperpar.htm

Home Site Index All About Bone Diagnostic Procedures for Bone Disorders ... Online Resources Primary Hyperparathyroidism Did you know? The parathyroid glands are located in the neck, near the thyroid gland. These glands are responsible for calcium regulation. What is primary hyperparathyroidism? Primary hyperparathyroidism is a metabolic disorder in which one (or more) of the parathyroid glands produces too much parathyroid hormone, which can result in the loss of bone tissue. Primary hyperparathyroidism affects 28 out of 100,000 people in the US each year, and is more prevalent in women than in men. A function of the parathyroid hormone is to keep blood-calcium levels from going too low by releasing calcium from bones, conserving calcium that would be excreted by the kidneys, and increasing calcium absorption from food. When the hormone overacts, the result is a rise in the blood-calcium level. When one parathyroid gland becomes enlarged, the condition is called adenoma. When more than one becomes enlarged, the condition is called hyperplasia. Both of these conditions are benign (non-cancerous).

57. Persistent Hyperparathyroidism And Nephrocalcinosis Persistent hyperparathyroidism and Nephrocalcinosis. Presentation. A 44 year oldwomen presented for persistent hyperparathyroidism and nephrocalcinosis. http://brighamrad.harvard.edu/Cases/jpnm/hcache/1003/unknown.html

Joint Program in Nuclear Medicine Persistent Hyperparathyroidism and Nephrocalcinosis Presentation A 44 year old women presented for persistent hyperparathyroidism and nephrocalcinosis. She had removal of the two superior parathyroid glands at surgery 20 years earlier with only partial improvement after surgery. At the time of surgical exploration the lower parathyroid glands could not be identified. Her past medical history is remarkable for the diagnosis of Multiple Endocrine Neoplasia type I since age 22 including resection of a pancreatic insulinoma. To evaluate the hyperparathyroidism double phase technetium-99m sestamibi parathyroid scintigraphy was performed. Images Parathyroid scintigraphy Description of Findings Full case report Click here J. Anthony Parker, MD PhD, Tony_Parker@bidmc.harvard.edu

58. Hyperparathyroidism hyperparathyroidism up. Related topics other, hormones. Mitavitenewsletter big head or bran disease, This document is written http://vetgate.ac.uk/browse/cabi/detail/dc3991d46ccdac1dc2d50c680ddc894a.html

hyperparathyroidism [up] Related topics: other hormones Mitavite newsletter : big head or bran disease This document is written by Dr J H Stewart Bsc BVSc PhD MRCVS, an equine veterinarian and nutritionist who is employed by the Australian Feed Company as a resident consultant in Equine Nutrition. Big head or bran disease occurs in horses when they have a high phosphorus diet and graze in pastures which contain tropical and subtropical grasses. This document discusses the stages in the development of big head, clinical signs, treatment and prevention, pastures and lime, and supplementation. Horse feed products manufactured by the Australian Feed Company are briefly mentioned in this document. This site is hosted by "Cyberhorse" an Australian gateway providing horse related Web material. Australia animal nutrition feeding horses ... hyperparathyroidism Last modified 28/Mar/2003 [Low Graphics]

59. AmgenTrials.com  -  Hyperparathyroidism Enrolling Trials A Study of an Investigational Medication for Severe Primaryhyperparathyroidism or Parathyroid Cancer This study will assess an http://www.amgentrials.com/patients/additional_study_areas/additional_hyperparat

home your privacy contact us site map ... adjust font search for trials only about clinical trials about amgen news external resources Enrolling Trials A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer This study will assess an investigational medication for patients with severe primary hyperparathyroidism or parathyroid cancer. The Call Center will be able to assess if a study center is near you. Please reference the study title when calling. Thank you. Additional legal information Heart Failure Hyperparathyroidism Show all Trials in Condition ... additional study areas

60. Detailed Discussion Hyperparathyroidism Detailed Discussion. Secondary hyperparathyroidism. Melissa Sciences. Thepatient was referred to Nuclear Medicine due to hyperparathyroidism. http://www.mcg.edu/radscape/CaseStudies/Melissa_Newman/ParaMelissaDiscussion.htm

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