41. Digital Urology Journal: Interstitial Cystitis interstitial cystitis. The urinary system consists of the kidneys, ureters, bladder,and urethra. National interstitial cystitis Database Study Clinical Centers. http://www.duj.com/IC.html

INTERSTITIAL CYSTITIS The urinary system consists of the kidneys, ureters, bladder, and urethra. The kidneys, a pair of purplish-brown organs, are located below the ribs toward the middle of the back. The kidneys remove liquid waste from the blood in the form of urine, keep a stable balance of salts and other substances in the blood, and produce erythropoietin, a hormone that aids the formation of red blood cells. Narrow tubes called ureters carry urine from the kidneys to the bladder, a triangle-shaped chamber in the lower abdomen. Like a balloon, the bladder's elastic walls relax and expand to store urine and contract and flatten when urine is emptied through the urethra. The typical adult bladder can store about 1 1/2 cups of urine. Adults pass about a quart and a half of urine each day. The amount of urine varies, depending on the fluids and foods a person consumes. The volume formed at night is about half that formed in the daytime. Normal urine is sterile. It contains fluids, salts and waste products, but it is free of bacteria, viruses and fungi. The tissues of the bladder are isolated from urine and toxic substances by a coating that discourages bacteria from attaching and growing on the bladder wall. People with interstitial cystitis (IC) have an inflamed, or irritated, bladder wall. This inflammation can lead to scarring and stiffening of the bladder, decreased bladder capacity, glomerulations (pinpoint bleeding) and, in rare cases, ulcers in the bladder lining.

42. Interstitial Cystitis - Urological Disorders Health Guide Urological Disorders. interstitial cystitis (IC). What is interstitialcystitis (IC)? interstitial cystitis (IC) is complex, chronic http://www.umm.edu/urology-info/intersti.htm

Urological Disorders Urogenital Disorders... Analgesic Nephropathy Cystocele ... Site Index Related Resources Within UMM Urology Urological Disorders Interstitial Cystitis (IC) What is interstitial cystitis (IC)? Interstitial cystitis (IC) is complex, chronic disorder characterized by an inflamed, or irritated, bladder wall. It can lead to scarring and stiffening of the bladder, decreased bladder capacity, glomerulations (pinpoint bleeding) and, in rare cases, ulcers in the bladder lining. IC may also be known as: painful bladder syndrome frequency-urgency-dysuria syndrome An estimated 500,000 people have IC, and about 90 percent of them are women. People of any age can be affected with IC, although it is rare in children. About two-thirds of patients are in their 20's, 30's, or 40's. There is no evidence that the disorder is hereditary, or genetically passed from parent to child. What are some of the types of IC? IC symptoms and severity vary greatly. It is believed that it may be several diseases, not just one. Two types of IC are usually diagnosed and listed below: nonulcerative IC: this is the most common type of IC, and usually affects young to middle-age women who have a normal, near normal, or increased bladder capacity. Glomerulations can be seen in the bladder wall.

43. NIH Guide: BASIC RESEARCH IN INTERSTITIAL CYSTITIS BASIC RESEARCH IN interstitial cystitis RELEASE DATE November 25, 2002 RFA DK03-010National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-03-010.html

BASIC RESEARCH IN INTERSTITIAL CYSTITIS RELEASE DATE: November 25, 2002 RFA: DK-03-010 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ( www.niddk.nih.gov http://www.niddk.nih.gov/fund/other/bladderprg_web/index.html http://www.niddk.nih.gov/fund/grants_process/revmech.htm http://grants.nih.gov/grants/funding/modular/modular.htm ... http://grants.nih.gov/grants/policy/data_sharing/index.htm WHERE TO SEND INQUIRIES We encourage inquiries concerning this RFA and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into two areas: scientific/research and financial or grants management issues: o Direct your questions about scientific/research issues to: Chris Mullins, Ph.D. Director of Basic Cell Biology Programs Division of Kidney, Urologic and Hematologic Diseases National Institute of Diabetes, Digestive and Kidney Diseases 6707 Democracy Blvd., Room 637 Bethesda, MD. 20892-5458 Telephone: (301) 594-7717 FAX: (301) 480-3510 E-mail: cm419z@nih.gov

44. NIH Guide: INTERSTITIAL CYSTITIS CLINICAL RESEARCH NETWORK (ICCRN) interstitial cystitis CLINICAL RESEARCH NETWORK (ICCRN) RELEASE DATE September 17,2002 RFA DK03-003 National Institute of Diabetes and Digestive and Kidney http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-03-003.html

INTERSTITIAL CYSTITIS CLINICAL RESEARCH NETWORK (ICCRN) RELEASE DATE: September 17, 2002 RFA: DK-03-003 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ( http://www.niddk.nih.gov http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-03-004.html http://www.niddk.nih.gov/patient/patient.htm#policy jk61x@nih.gov Leroy M. Nyberg, Ph.D., M.D. Urology Program Director Division of Kidney, Urologic and Hematologic Diseases National Institute of Diabetes and Digestive and Kidney Diseases Two Democracy Plaza, Room 617 6707 Democracy Boulevard Bethesda, MD 20892-5458 Telephone: (301) 594-7717 Fax: (301) 480-3510 Email: ln10f@nih.gov o Direct your questions about peer review issues to: Francisco O. Calvo, Ph.D. Chief, Review Branch Division of Extramural Activities National Institute of Diabetes and Digestive and Kidney Diseases 6707 Democracy Boulevard Room 752, MSC 5452 Bethesda, MD 20892-5452 Telephone: (301) 594-8885 FAX: (301) 480-3505 Email: fc15y@nih.gov

45. Ask Dr Stoll - Interstitial Cystitis http://askwaltstollmd.com/cystitis.html

46. Dr Roby's Hormone Center: Interstitial Cystitis Treatment interstitial cystitis Allergy causes softtissue swelling and irritation. Thisis what is referred to as interstitial cystitis. http://www.onlineallergycenter.com/interstitialcystitis/

Caution! Visit Microsoft's Web site to obtain the newest version of Internet Explorer, or visit Visiting this web site without first upgrading your browser may result in unreliable behavior. Dr. Roby's Hormone Center Home Page To Schedule an Appointment Prescriptions Speaking Engagements ... About Dr. Roby Dr. Roby Treats Asthma Chronic Fatigue Syndrome (CFS) Fibromyalgia Interstitial Cystitis ... Symptoms More Articles Sublingual Drops Ear Infections Cold or Allergy? Headaches ... WebMD Transcript Help Me! Ask Dr Roby FAQ Index Newsletter Wellness Store Online Store Resources Links Recommended Reading Protocol: Physicians Only Research Abstracts and Articles ... Sitemap Physician Login: Login or Join now Got a Question? E-mail Dr. Roby Web site of Dr. Russell Roby Interstitial Cystitis Allergy causes soft-tissue swelling and irritation. It causes irritation of mucus membrane, in the eyes, ears, nose and throat, and in the urinary tract. When there is irritation in the throat, there is disruption of the tissue integrity and severe irritation may result. The most obvious example is the chronic "sore throat" that many allergy suffers experience. The constant mucus drainage and resultant histamine release result in tiny disruptions in the protective surface layers of the mucus membrane lining the throat. This disruption makes the sensitive subsurface layers susceptible to irritants such as spices or acid foods like hot sauce and orange juice. And that leads to even more irritation and even hemorrhagic tissue changes (bleeding). This disruption also allows the ordinarily harmless bacteria that are necessary for digestion to set up local infections in the irritated tissues.

47. THE MERCK MANUAL, Sec. 17, Ch. 227, Urinary Tract Infections Parasitic Infections. interstitial cystitis. interstitial cystitis. Interstitialcystitis (IC) is a chronic bladder disease occurring primarily in women. http://www.merck.com/pubs/mmanual/section17/chapter227/227d.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 17. Genitourinary Disorders Chapter 227. Urinary Tract Infections Topics Bacterial Infections Fungal Infections Parasitic Infections Interstitial Cystitis Interstitial Cystitis Interstitial cystitis (IC) is a chronic bladder disease occurring primarily in women. Etiology is unknown. The bladder wall shows inflammatory infiltration with mucosal ulceration and scarring that results in smooth muscle contraction, diminished urinary capacity, hematuria, and frequent, painful urination. Carcinoma in situ can mimic IC and must be ruled out. Bladder distension may provide excellent, but transient, relief. Intravesical agents (eg, dimethyl sulfoxide [DMSO], methylprednisolone, heparin sulfate) and oral therapy with anticholinergics or tricyclic antidepressants offer some relief. Rarely, augmentation cystoplasty may be undertaken. Very rarely, cystectomy with urinary diversion is required.

48. Health Report - 10/13/1997: Interstitial Cystitis interstitial cystitis Broadcast Monday 13 October 1997 with. Summary NormanSwan And all they've got is interstitial cystitis. Dr http://www.abc.net.au/rn/talks/8.30/helthrpt/stories/s319.htm

Health Matters All in the Mind The Buzz Earthbeat ... Quantum Interstitial Cystitis Broadcast Monday 13 October 1997 with Summary: This story is about a hidden, painful and debilitating bladder problem which affects primarily women. It is not to be confused with normal cystitis. Transcript: Norman Swan: Now your letters are always welcome here on the Health Report and one particularly sparked my interest recently. It came from Diane Turner in Warragul, Victoria who asked us to cover the hidden, painful and debilitating problem of interstitial cystitis. Since it primarily affects women (and isn't by the way to be confused with normal cystitis), I went to Dr Helen O'Connell. Helen is at the Royal Melbourne Hospital and is the only female urologist in Australasia. Dr O'Connell: Interstitial cystitis is a condition where the patients predominant symptom is bladder related discomfort. It's a non malignant, non infective condition which may be associated with changes that are apparent when you look at the bladder, but sometimes the bladder may appear absolutely normal, that the patient may be crippled with discomfort. Norman Swan: And what sort of discomfort do they complain of. What are the typical range of stories?

49. Health Report - 12/01/1998: Interstitial Cystitis (Repeat) with Norman Swan interstitial cystitis (Repeat) Monday 12 January1998. Norman Swan And all they've got is interstitial cystitis. http://www.abc.net.au/rn/talks/8.30/helthrpt/stories/s10308.htm

Radio National with Norman Swan Interstitial Cystitis (Repeat) Monday 12 January 1998 Summary: This is a hidden, painful and debilitating bladder problem which affects primarily women. It is not to be confused with normal cystitis. (This is a repeat of part of a programme first broadcast on 13th October 1997). Norman Swan: Now your letters are always welcome here on the Health Report and one particularly sparked my interest recently. It came from Diane Turner in Warragul, Victoria who asked us to cover the hidden, painful and debilitating problem of interstitial cystitis. Since it primarily affects women (and isn't by the way to be confused with normal cystitis), I went to Dr Helen O'Connell. Helen is at the Royal Melbourne Hospital and is the only female urologist in Australasia. Dr O'Connell: Interstitial cystitis is a condition where the patients predominant symptom is bladder related discomfort. It's a non malignant, non infective condition which may be associated with changes that are apparent when you look at the bladder, but sometimes the bladder may appear absolutely normal, that the patient may be crippled with discomfort. Norman Swan: And what sort of discomfort do they complain of. What are the typical range of stories?

50. Interstitial Cystitis Symptoms, Causes And Treatments interstitial cystitis, or painful bladder syndrome, causes bladder pain and involuntarybladder spasms. interstitial cystitis Symptoms, Causes and Treatments. http://www.bladder-disorders.com/html/interstitial_cystitis.php3

Interstitial Cystitis: Symptoms, Causes and Treatments Interstitial cystitis, sometimes called Painful Bladder Syndrome , is a chronic and painful inflammation of the bladder wall. Stress appears to aggravate bladder pain and spasms, but the exact causes of interstitial cystitis are unclear: tests for infections usually come back negative. Researchers believe that painful bladder syndrome may actually be several different diseases, as bladder pains, spasms and duration of the disease vary widely from patient to patient. Some 700,000 people in the United States suffer from interstitial cystitis, with 90% of these patients being women. Why women are more susceptible to painful bladder syndrome than men is not known. Symptoms of Interstitial Cystitis Symptoms of painful bladder syndrome are similar to many other bladder diseases. The patient urinates frequently, often having to get up several times at night to urinate. Due to involuntary bladder spasms, patients feel sudden, urgent needs to urinate, and a burning sensation when urinating. Interstitial cystitis sufferers also experience mild to severe bladder pain. Symptoms may clear up seemingly at random, only to resurface later. Diagnosis of interstitial cystitis begins by ruling out other bladder disorders. Once this is done, a cystoscopic exam may be called for. With the patient under anesthesia the doctor inserts a thin tube into the bladder to examine the bladder walls. Small hemorrhages or ulcers on the bladder walls would suggest a possible diagnosis of interstitial cystitis.

51. Interstitial Cystitis Symptoms, Causes And Treatments interstitial cystitis, or painful bladder syndrome, causes bladderpain and involuntary bladder spasms. Learn about the symptoms http://www.bladder-disorders.com/html/interstitial-cystitis.php3

Interstitial Cystitis: Symptoms, Causes and Treatments Interstitial cystitis, sometimes called Painful Bladder Syndrome , is a chronic and painful inflammation of the bladder wall. Stress appears to aggravate bladder pain and spasms, but the exact causes of interstitial cystitis are unclear: tests for infections usually come back negative. Researchers believe that painful bladder syndrome may actually be several different diseases, as bladder pains, spasms and duration of the disease vary widely from patient to patient. Some 700,000 people in the United States suffer from interstitial cystitis, with 90% of these patients being women. Why women are more susceptible to painful bladder syndrome than men is not known. Symptoms of Interstitial Cystitis Symptoms of painful bladder syndrome are similar to many other bladder diseases. The patient urinates frequently, often having to get up several times at night to urinate. Due to involuntary bladder spasms, patients feel sudden, urgent needs to urinate, and a burning sensation when urinating. Interstitial cystitis sufferers also experience mild to severe bladder pain. Symptoms may clear up seemingly at random, only to resurface later. Diagnosis of interstitial cystitis begins by ruling out other bladder disorders. Once this is done, a cystoscopic exam may be called for. With the patient under anesthesia the doctor inserts a thin tube into the bladder to examine the bladder walls. Small hemorrhages or ulcers on the bladder walls would suggest a possible diagnosis of interstitial cystitis.

52. Interstitial Cystitis (Bladder) interstitial cystitis (IC) is an inflammation of the bladder which can occur byitself or in conjunction with other autoimmune diseases, such as fibromyalgia http://www.sclero.org/medical/symptoms/associated/interstitial-cystitis/a-to-z.h

ISN: How We Help ISN Representatives Join or Donate Search This Site The Web Scleroderma from A to Z Hope on Horizon Welcoming Email MEDICAL ... EMAIL We're dedicated to helping you find the comfort and/or information you need for dealing with scleroderma or related illnesses. Please feel free to email me at any time. Shelley Ensz, Webmaster The International Scleroderma Network (ISN) Now Available in 18 Languages: Bahasa Malaysia Chinese Deutsche (German) English ... Worldwide Support Groups Select Medical Topic Here What is Scleroderma? Causes of Scleroderma Difficult Diagnosis Types of Scleroderma Localized: - Linear Scleroderma - Morphea Scleroderma - Juvenile Scleroderma Systemic: - CREST Syndrome - Diffuse Scleroderma - Limited Scleroderma - Overlap/MCTD/UCTD Photos of Scleroderma Symptoms Scleroderma Specialists Scleroderma Registries U.K. Registry Ineffective or Unproven Alternative Medicine Scleroderma Symptoms Cardiac (Heart) Dental/Mouth Gastrointestinal Liver Pulmonary (Lungs) Raynaud's (Cold Hands/Feet) Renal (Kidney) Calcinosis Fibrosis (Hardening) Telangiectasia (Spider Veins) Xerosis (Dry Skin) SIMILAR TO SCLERODERMA Arthritis/Dermatology (General) Atrophoderma of Pierini/Pasini Eosinophilic Fasciitis Eosinophilia-Myalgia (EMS) Glossary of Skin Disorders Lichen Sclerosis

53. BladderCommunity: Interstitial Cystitis interstitial cystitis. The urinary system consists of the kidneys, ureters,bladder, and urethra. National interstitial cystitis Database Study. http://www.bladder.org/Interstitial Cystitis.html

INTERSTITIAL CYSTITIS The urinary system consists of the kidneys, ureters, bladder, and urethra. The kidneys, a pair of purplish-brown organs, are located below the ribs toward the middle of the back. The kidneys remove liquid waste from the blood in the form of urine, keep a stable balance of salts and other substances in the blood, and produce erythropoietin, a hormone that aids the formation of red blood cells. Narrow tubes called ureters carry urine from the kidneys to the bladder, a triangle-shaped chamber in the lower abdomen. Like a balloon, the bladder's elastic walls relax and expand to store urine and contract and flatten when urine is emptied through the urethra. The typical adult bladder can store about 1 1/2 cups of urine. Adults pass about a quart and a half of urine each day. The amount of urine varies, depending on the fluids and foods a person consumes. The volume formed at night is about half that formed in the daytime. Normal urine is sterile. It contains fluids, salts and waste products, but it is free of bacteria, viruses and fungi. The tissues of the bladder are isolated from urine and toxic substances by a coating that discourages bacteria from attaching and growing on the bladder wall. People with interstitial cystitis (IC) have an inflamed, or irritated, bladder wall. This inflammation can lead to scarring and stiffening of the bladder, decreased bladder capacity, glomerulations (pinpoint bleeding) and, in rare cases, ulcers in the bladder lining.

54. Interstitial Cystitis (Bladder Disorder) own keywords. interstitial cystitis. Printerfriendly version PDFfile, 161 Kb. What is interstitial cystitis? interstitial cystitis http://www.4woman.gov/faq/intcyst.htm

Search our database by Health Topic or enter your own keywords INTERSTITIAL CYSTITIS Printer-friendly version PDF file, 161 Kb] What is interstitial cystitis? What are the causes of interstitial cystitis? What are some symptoms and signs of interstitial cystitis? How is interstitial cystitis diagnosed? ... I have interstitial cystitis and have just discovered I am pregnant. Will it affect my baby in any way? What is interstitial cystitis? Interstitial cystitis (IC) is a chronic bladder condition that can cause pain and other symptoms. People with IC have an inflamed or irritated bladder wall. This inflammation can lead to: scarring and stiffening of the bladder; less bladder capacity (the bladder is able to hold less urine); pinpoint bleeding in the bladder lining. In rare cases, ulcers form in the bladder lining. Of the more than 700,000 Americans estimated to have IC, about 90 percent are women. Severe cases of IC can be very disabling. What are the causes of interstitial cystitis? No one knows what causes interstitial cystitis. Because IC varies so much in symptoms and severity, most researchers believe that it may actually be several diseases. One theory being studied is that IC is an autoimmune response following a bladder infection. Another theory is that there are substances in urine which are irritating to people with IC. Other theories are also being studied. Interstitial cystitis is different from urinary tract infections, which are caused by bacteria and can be treated with antibiotics. Studies have shown that antibiotics are not useful for treating IC.

55. Www.fibromyalgia.com interstitial cystitis is a chronic inflammatory condition of the bladder. The causeof interstitial cystitis is unknown, but occurs more commonly in females. http://www.fibromyalgia.com/interstitial_cystitis.htm

document.writeln(DayofWeek[DoW] + ' - ' + Month[Mon] + Day + ', ' + Year) Home Research Getting Help Fibromyalgia Tender Points ... Pain Bugs The Pain Dairies Interstitial cystitis is a chronic inflammatory condition of the bladder. The cause of interstitial cystitis is unknown, but occurs more commonly in females. Symptoms include difficulty urinating, pain on urination, urinary urgency and increased frequency of urination. Question: I'm currently taking Vistaril, Benadryl, Bicitra, Zantac, L-Arginine, Diflucan and am on IC Diet. What do you think? Answer: This is an OK list of medications. Histaryl and Benedryl are both antihistamines. Zantac, as you might not have known, is also an antihistamine. Both work at two different receptors. L-arginine is probably useless and, in fact, may actually enhance central activation as amino acids play in the trascriptive process of the second order neuron. A lot of big words, but I don't like it. That's a lot of Diflucan you're taking. You usually only need one or two doses. Run this by your primary care physician. The IC Diet is probably helpful. If these are all the medicines you're on, you're probably a little undertreated. I really like Neurontin. New meds are on the way. Keep watching the page.

56. HealthlinkUSA Interstitial Cystitis Links Wednesday February 5, 2003. The healthy way to search today's best sites.Links to websites which may include treatment, cures, diagnosis http://www.healthlinkusa.com/168ent.htm

57. HealthlinkUSA Interstitial Cystitis Links of the treatment process. FindWhat. Click here for page 1 of InterstitialCystitis information from the HealthlinkUSA directory. http://www.healthlinkusa.com/Interstitial_Cystitis.htm

58. EMedicine - Interstitial Cystitis : Article By Eric Rovner, MD interstitial cystitis interstitial cystitis (IC) is a clinical syndrome characterizedby daytime and nighttime urinary frequency, urgency, and pelvic pain of http://www.emedicine.com/MED/topic2866.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Urology Interstitial Cystitis Last Updated: July 17, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Indications Relevant Anatomy And Contraindications ... Bibliography Author: Eric Rovner, MD , Co-Director of Female Urology, Neurourology and Urodynamics, Assistant Professor, Department of Surgery, Division of Urology, University of Pennsylvania Coauthor(s): Ricardo Sanchez-Ortiz, MD , Clinical Instructor, Department of Surgery, Division of Urology, University of Pennsylvania School of Medicine Eric Rovner, MD, is a member of the following medical societies: Alpha Omega Alpha American Medical Association American Urogynecologic Society American Urological Association , and International Continence Society Editor(s): Jong M Choe, MD, FACS

59. Interstitial Cystitis What Is interstitial cystitis? Interstitial 25). interstitial cystitis Helpfor a puzzling illness. New York Times,p. B7. Hanno, P. (1998). http://www.medhelp.org/NIHlib/GF-306.html

What Is Interstitial Cystitis? What Causes IC? Are There Different Types of IC? How Is IC Diagnosed? ... Other Resources What Is Interstitial Cystitis? Interstitial cystitis (IC), one of the chronic pelvic pain disorders, is a condition resulting in recurring discomfort or pain in the bladder and the surrounding pelvic region. The symptoms of IC vary from case to case and even in the same individual. People may experience mild discomfort, pressure, tenderness, or intense pain in the bladder and surrounding pelvic area. Symptoms may include an urgent need to urinate (urgency), frequent need to urinate (frequency), or a combination of these symptoms. Pain may change in intensity as the bladder fills with urine or as it empties. Women's symptoms often get worse during menstruation. In IC, the bladder wall may be irritated and become scarred or stiff. Glomerulations (pinpoint bleeding caused by recurrent irritation) may appear on the bladder wall. Some people with IC find that their bladders cannot hold much urine, which increases the frequency of urination. Frequency, however, is not always specifically related to bladder size; many people with severe frequency have normal bladder capacity. People with severe cases of IC may urinate as many as 60 times a day. Also, people with IC often experience pain during sexual intercourse. IC is far more common in women than in men. Of the more than 700,000 Americans estimated to have IC, 90 percent are women.

60. Re: Interstitial Cystitis Subject Re interstitial cystitis Forum The Urology Forum Topic Area Postedby HFHS MDMS on February 10, 1998 at 185546 In Reply to Interstitial http://www.medhelp.org/forums/urology/archive/116.html

Advertisement Welcome to Med Help! Questions in The Urology Forum are being answered by doctors from Henry Ford Health System , consistently ranked one of the best hospitals in America. Subject: Re: Interstitial Cystitis Forum: The Urology Forum Topic Area: Posted by HFHS M.D.-MS on February 10, 1998 at 18:55:46: In Reply to: Interstitial Cystitis posted by Amir on February 06, 1998 at 17:07:16: : I ask these questions on behalf of a young lady (about 35 years old) who has Interstitial Cystitis. : She has been having DMSO treatments and has been taking Heparin. : Recently, following continuous bladder pain, her doctor gave her Deca Peptyl. : What are the side effects of Deca Peptyl? : Are there additional medicines that are considered to be effective? : Are there any new therapy methods developed after 1996? : Can IC be completely cured nowadays? Dear Amir; Thanks for your question. Deca peptyl is the trade name for Triptorelin. It is not available in the US but other similar drugs are. It mimics a hormone that is normally secreted in your brain which at normal amounts and in pulses causes the testes or ovaries to secrete estrogen or testosterone. It is used in the medical in large doses. Used this way (nonpulsed) it “feedsback” to the brain and turns off the natural production of GNRH (Gonadal Releasing Hormone) thus turning off the estrogen or testosterone production in the testes and ovaries. This causes a chemical castration and hot flashes in both sexes, breast tenderness in males, mood disturbances, loss of muscle mass strength or vigor. It is used to treat prostate cancer which uses testosterone for fuel, endometriosis ( the abnormal growth of the womb lining in the wrong place ) and early puberty.

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