21. XXY/Klinefelter Syndrome History Your physician may have referred to this genetic condition as eitherXXY or klinefelter syndrome. Though these terms are often used http://47xxy.org/History.htm

TOP History What is XXY?: What is XXY? History XXY or Ks? Treatment ... In Conclusion To print all 9 of the above sections as one complete document, click here Your physician may have referred to this genetic condition as either XXY or Klinefelter syndrome. Though these terms are often used interchangeably, they actually refer to two quite different, though related, conditions. In 1942, Dr. Harry Klinefelter while working at the Massachusetts General Hospital in Boston published with fellow researchers a report about nine individuals who had similar features: tall (around six feet) small testes or hypogonadism inability to produce sperm sparse facial and body hair gynecomastia By the late 1950's researchers discovered that those with these features (Klinefelter syndrome) , had an extra X sex chromosome, and were XXY instead of the typical male arrangement of XY. Back - What is XXY? Next - XXY or Ks? Aneuploidies E - Mail Lists ... Top This page first created: May 24, 1999 Bottom

22. Hospital Practice: Klinefelter Syndrome Diagnosis and Treatment of klinefelter syndrome CYNTHIA M. SMYTH Universityof Washington. Table 1. Clinical Signs of klinefelter syndrome. http://www.hosppract.com/issues/1999/0915/cesmyth.htm

Diagnosis and Treatment of Klinefelter Syndrome CYNTHIA M. SMYTH University of Washington Many physicians underestimate the prevalence of Klinefelter syndrome and so fail to recognize its more obvious features. Increased awareness of its effects on physical, psychological, and social development should help to dispel persistent misconceptions about the condition and enable earlier diagnosis and more effective treatment. Dr. Smyth is in private practice and is also Clinical Instructor, Department of Internal Medicine, University of Washington, Seattle. Klinefelter syndrome is one of the most common causes of hypogonadism, affecting one in 500 men and boys. In two thirds of cases, the chromosomal karyotype is 47,XXY; in the remainder, variant and mosaic karyotypes predominate (Figure 1). Expression of the syndrome varies with the number of X chromosomes and the degree of endocrinologic dysfunction. The patient's history and physical examination provide enough information to diagnose the condition in puberty, but most patients do not seek medical attention until adulthood, when problems such as impotency or infertility become an issue. The following case is typical. Case Presentation A 44-year-old man presented to his primary care physician complaining of erectile dysfunction and infertility. Although he and his wife were able to have intercourse, they had been unable to have children. On questioning, he said that he was aware that he did not have the same libido as many of his friends. He had gone through puberty late and had not begun to shave until age 17. He had had academic, psychological, and social difficulties as a teenager and had been treated for depression as an adult. He had not had major medical problems such as high blood pressure or diabetes and did not drink or smoke.

23. Klinefelter's Syndrome Klinefelter's Syndrome. What is Klinefelter's Syndrome? Booklet onklinefelter syndrome Contact Group Klinefelter's syndrome is http://www.aaa.dk/TURNER/ENGELSK/KLINEN.HTM

Klinefelter's Syndrome. What is Klinefelter's Syndrome? Booklet on Klinefelter Syndrome Contact Group Klinefelter's syndrome is found in approximately 1 of 700 men, i.e. there are approximately 3600 boys and men with Klinefelter's syndrome in Denmark with 5 million inhabitants. Men usually have but one X and one Y chromosome, i.e. the chromosomeconstitution 46,XY. Men with Klinefelter's syndrome have more than one X chromosome, usually two X chromosomes, i.e. the chromosome constitution 47,XXY. At birth the testicles of Klinefelter boys are of normal size. When the testicles grow quickly in boys with normal chromosomes at the age of 11-12 years, the testicles of Klinefelter boys stay very small, as a rule only 2 cms. from pole to pole. Usually only few sperms are developed in the testicles, and men with Klinefelter's syndrome are as a rule infertile. Boys with Klinefelter's syndrome should be treated with testosterone, usually from the 11 or 12 years of age, best with Restandol tablets (Testosteroneundecanoat), which does not affect the liver, or with injections of other testosterone preparations. Klinefelter boys more often than other boys have delayed motor function, speech, and maturation development, which does not make them patients demanding special treatment. It is important that these boys at an early age go to a good day-care institution, and that there is a close cooperation between parents and day-care institution staff. If the speech development is delayed, it is important to get help from a speech-therapist for a period. Regarding the motor function development, the participation of parent/child in sports activities and group activities of any kind is of great value. The same is the case with regard to stimulating the delayed development in maturation. In this connection it must be mentioned, that it is also important to stimulate these boys to independence, and not in any way to overprotect them.

24. Klinefelter Syndrome klinefelter syndrome resources, national and international support groups,clinics with genetic counselors and geneticists. klinefelter syndrome. http://www.kumc.edu/gec/support/klinefel.html

Klinefelter syndrome PO Box 119 Roseville, CA 95678-0119 Phone: 916.773.1449 Fax: 916.773.1449 E-mail: help@genetic.org Web site: http://www.genetic.org/ks/ Japenese version) Resources for families Introductory video about XXY , by mother whose son has Klinefelter Syndrome - The Even Exchange, Newsletter American Association for Klinefelter Syndrome Information and Support (AAKSIS) Klinefelter Syndrome Support Group Home Page numerous links to other organizations and resources, created by an adult with Klinefelter Syndrome, regional groups, varients, international groups International Groups: Australia Australian Klinefelter Support Group 4 Victoria Rd Acquire Fields NEW 02564 AUSTRALIA Victoria Support Group 41 Jesmond Rd Cordon, Victoria 03136 AUSTRALIA Klinefelter Syndrome Support Group P.O.Box 3 Glendenning Mail Center NEW 2761 AUSTRALIA Canada Canada Klinefelter Support Group Apt. 3, 2867 Young St. Toronto, ON. Canada M4N 2J5 England (United Kingdom) Klinefelter's Syndrome Association 56 Little Yeldham Road Little Yeldham, Halstead, Essex CO9 4QT

25. Klinefelter Syndrome And Associates The summary for this Japanese page contains characters that cannot be correctly displayed in this language/character set. http://www.tokyo-med.ac.jp/genet/ks/indexj.html

ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQiKlinefelter Syndromej‚Æ‚»‚Ì’‡ŠÔ’B WWWƒz[ƒ€ƒy[ƒWiWorld Wide Web Home Pagej ‰pŒê‚̃IƒŠƒWƒiƒ‹ƒy[ƒW‚Í‚±‚¿‚ç ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQ‚Æ‚»‚Ì’‡ŠÔ’B‚̓Nƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQ‚Æ‚»‚̈ŸŒ^‚̈â“`Žqó‘Ô‚É‚ ‚銳ŽÒ‚³‚ñ’B‚ðŽx‚¦‚é”ñ‰c—˜Žx‰‡‘gD‚Å‚·D Ž„‚½‚¿‚Ì‘gD‚ɂ‚¢‚Ä(‰p•¶) ‘—§/’n•û‚ÌŽx‰‡‘gDƒjƒ [ƒX‚Ɖ(‰p•¶) 1997”N7ŒŽ25“ú`27“úŠJ‚̃VƒJƒS‰ï‹c‚̏î•ñ! ‚»‚Ì‘¼! ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[Žx‰‡ E-Mail ƒŠƒXƒg(‰p•¶) ÅV‚̍‘Û“IƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQŽx‰‡‚̃[ƒŠƒ“ƒOEƒŠƒXƒg ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQŒ¤‹†Œv‰æ(‰p•¶) Œ»Ý‚̃Nƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQ‚ÌŒ¤‹†Œv‰æ ‹»–¡[‚¢•ñ“¹Ž‘—¿(‰p•¶) Ž„‚½‚¿‚ªŽó‚¯Žæ‚Á‚½•ñ“¹ŠÖŒWŽ‘—¿ ‰ß‹Ž‚̃jƒ [ƒXEƒŒƒ^[(‰p•¶) ƒjƒ [ƒXEƒŒƒ^[ The Even Exchange ‚æ‚è‚Ì”²ˆ‹LŽ– e ‘¼‚̏î•ñŒ¹(‰p•¶) A ƒpƒ“ƒtƒŒƒbƒgC‘ÐCƒŠƒ“ƒN‚Ȃǂ̃ŠƒXƒg‚Æ‚»‚Ì‘¼‚̏î•ñŒ¹ ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQŽÊ^‰æ˜L(‰p•¶) ƒNƒ‰ƒCƒ“ƒtƒFƒ‹ƒ^[ÇŒóŒQ‚̉Ƒ°‚̎ʐ^W ‚ ‚È‚½‚ÌŒäˆÓŒ©‚ð‚¨•·‚©‚¹‰º‚³‚¢! (‰p•¶) v‘¬‚È’²¸‚ðˆË—Š‚µ‚½‚¢DÚ‚µ‚¢î•ñ‚𓾂½‚¢DŽ„‚½‚¿‚̃jƒ [ƒXƒŒƒ^[‚ð—X•Ö‚Å‘—‚Á‚Ä—~‚µ‚¢DŽ„‚½‚¿‚É“`‚¦‚½‚¢‚±‚Æ‚ð‚±‚¿‚ç‚̃y[ƒW‚©‚炨‘—‚艺‚³‚¢D‚È‚¨C‹°‚ê“ü‚è‚Ü‚·‚ªC‚±‚̃y[ƒW‚͉p•¶‚̃y[ƒW‚Å‚·‚̂ŁC‚¨ŽèŽ†‚à‰p•¶‚É‚Ä‚¨Šè‚¢‚µ‚Ü‚·D Klinefelter Syndrome and Associates P.O. Box 119

26. Gynecomastia.org 1999. klinefelter syndrome, GENERAL INTEREST SURVEY. at age 62 to confirm KlinefelterSyndrome. at age 21 - Army doctor noticed tiny testes and small penis. http://www.gynecomastia.org/content/general/klinsyd.shtml

Front Page Discussion Boards Old Discussion Boards GENERAL INFORMATION Gynecomastia In Men Dr. Delgado's FAQ Medical Articles Gilbert's Syndrome ... In The Press TREATMENT OPTIONS Living With Gynecomastia Drugs With Side Effects Hormones Surgeon Listings ... Horror Stories MISCELLANEOUS Male Gynecomastia Questionaire Mailing Lists Contact Us SURGERY EXPERIENCES Letter 00080601 Letter 0080602 A Mother's Story Letter 01012701 ... FastCounter by bCentral (as of 8/11/01) Klinfelter Syndrome S-ca.......(sex-chromosome abnormality) FREQUENTLY ASKED QUESTIONS (FAQ) WHAT IS S-CA? It is a genetic disorder, which occurs at conception. It is only found in males and the chromosomes in the sex line has at least one extra "X". To date, it is unknown whether the extra X comes from the father or the mother or from both parents. In the medical community, it is more commonly known as 47,xxy, but there are many variants to this genetic structure, such as XXXY, XXXXY, XXYY, XX/XXY, XY/XXXY, XX/XXY, XY/XXY, XXY/XXXXY, XxY/Xx/XY, XXXYY, XXY/XX, XXY/XY, XXY/XYY, XXY/XXXY, XXX/XXXY, XXXXY/XXXXXY/XXX, XX(Y), XXXXYY/XXXXY/XXX, XO/XY/XXY, YO/XY,XXY, XO/XX/XY/XXY/XXXY, XY/XXY/XXxY, XY/XXY/XXXY, XX/XxY, XX/XY/XXY WHAT ARE THE MOST COMMON SYMPTOMS?

27. The Contact A Family Directory - KLINEFELTER SYNDROME printer friendly, klinefelter syndrome, KLINEFELTER'S SYNDROME ASSOCIATION.Sue Cook Klinefelter's Syndrome Association 56 Little Yeldham http://www.cafamily.org.uk/Direct/k18.html

printer friendly KLINEFELTER SYNDROME home more about us in your area conditions information ... how you can help search this site Klinefelter Syndrome: XXY Syndrome (XXXY and XXXXY are sometimes included) This syndrome occurs only in males and is due to a chromosomal abnormality.A chromosome is a rod-like structure present in the nucleus of all body cells, with the exception of the red blood cells, and which stores genetic information. Normally humans have 23 pairs of chromosomes, the unfertilised ova and each sperm carrying a set of 23 chromosomes. On fertilisation the chromosomes combine to give a total of 46 (23 pairs). A normal female has an XX pair and a normal male an XY pair. The male affected by Klinefelter Syndrome has two X chromosomes, as well as one Y, resulting in the formation XXY. A mosaic form also occurs where only a percentage of body cells contain XXY while the remainder carry XY. The extent of the affect will depend upon the proportion of XXY to XY throughout the body. There is an enormous variation in the expression of this condition. Some men are entirely normal and the diagnosis is only made for an incidental reason. It is important to give an open diagnosis to such children and not just paint a picture of the "full blown" condition which is described below. It may be that just some of the features are present, such as tall stature or delayed puberty.

28. LookSmart - Klinefelter Syndrome klinefelter syndrome. Associates klinefelter syndrome Learn about what thedisease is and how to treat it, including support-group information. http://www.looksmart.com/eus1/eus302562/eus317837/eus317920/eus53948/eus89791/eu

29. Tall Persons Club GB & Ireland · Medical Information · Klinefelter Syndrome klinefelter syndrome, back to Medical Information. klinefelter syndrome was firstdescribed in 1942, its chromosomal basis was not confirmed until 1959. http://www.tallclub.co.uk/medical/klinefelter.asp

Home Bulletin Board (BBS) Chat Room Events ... Member Login Klinefelter Syndrome back to Medical Information Abnormalities of the sex chromosomes occur in about 1.5 per 1000 births, meaning that about 1200 children are born each year with one of these conditions. Turners syndrome, in which all or part of the X chromosome is missing, affects only girls, and is easily recognised, with short stature being an obvious symptom. At birth, infants are often smaller in respect of birthweight, length, and head circumference. During childhood, growth tends to be ahead of the child's peers, particularly in terms of leg length. Even by the age of three years leg length may be disproportionate to sitting height. In a clinical study of XXY boys, two thirds of the boys developed steadily increasing obesity, while the rest displayed lean and lanky stature. In three boys, who had high growth velocities, malposition of the testes was observed, with ascent of one testis occuring, requiring orchidopexy. Testicular development was normal up to the age of one year, apart from a reduction in the number of spermatogonia. Later, tubular diameter became reduced, and germ cells were not seen. Testicular volume increased in all boys at puberty, but this was followed by involution in those with the greatest development, resulting in a slight reduction in final volume.

30. Special Child: Disorder Zone Archives - Klinefelter Syndrome Disorder Zone Archives. klinefelter syndrome. Introduction. American Associationfor klinefelter syndrome Information and Support http//www.aaksis.org/KS.html; http://www.specialchild.com/archives/dz-032.html

Disorder Zone Archives Klinefelter Syndrome Introduction Klinefelter syndrome (KS) is a genetic disorder that is thought to be the most common chromosomal variation found in humans, with an occurrence rate of 1 in every 500 to 1,000 live born males. KS, which is found exclusively in males, is caused by a variation in the sex chromosomes, resulting in a hormone imbalance. KS occurs when a male has an extra X chromosome. That is, instead of having the typical 46 chromosomes, males with KS have 47 (typical males are classified as 46, XY, where they inherit the X chromosome from their mother and the Y chromosome from their father; males with KS are 47, XXY). The extra chromosome can be inherited from either the mother or the father, however, advanced maternal age does increase the risk slightly of having a child with XXY. KS was first described in 1942 by Dr. Harry Klinefelter and coworkers at Massachusetts General Hospital in Boston. In the late 1950's it was then revealed by other researchers that the cause of KS was due to an extra X chromosome. Features and Characteristics Not all males with XXY actually develop the syndrome (or its symptoms and characteristics). In fact, many males show no abnormalities at all. However, for those who have developed KS, the following characteristics have been identified:

31. HealthlinkUSA Klinefelter Syndrome Links of the treatment process. FindWhat. Click here for page 1 of KlinefelterSyndrome information from the HealthlinkUSA directory. http://www.healthlinkusa.com/174ent.htm

32. Klinefelter Syndrome; Treatment, Prevention, Cure klinefelter syndromeSearch information from many of the best KlinefelterSyndrome health sites. Quickly find information treatments http://www.healthlinkusa.com/content/174.html

33. Ambiguous Genitalia klinefelter syndrome, Book, Home Page. http://www.fpnotebook.com/END164.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Endocrinology Sex Pituitary Disease Assorted Pages Ambiguous Genitalia Female Pseudohermaphroditism Male Pseudohermaphroditism True Hermaphroditism ... Gynecomastia Ambiguous Genitalia Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Endocrinology Index Adrenal Disease General Cardiovascular Medicine Diabetes Mellitus Examination Ophthalmology Geriatric Medicine Growth Hematology and Oncology Hypoglycemia Laboratory Metabolism Neonatology Obesity Obstetrics Parathyroid Disease Pediatrics Pharmacology Pituitary Disease Prevention Radiology Nephrology Sex Sports Medicine Surgery Symptom Evaluation Thyroid Disease Page Sex Index Ambiguous Genitalia Ambiguous Hermaphrodite Female Ambiguous Hermaphrodite Male Ambiguous Hermaphrodite True Gonadal Dysgenesis Klinefelter Gonadal Dysgenesis Turners Syndrome Pituitary Kallmann Puberty Delay Puberty Delay Eugonadotropic Puberty Delay Hypergonadotropic Puberty Delay Hypogonadotropic Puberty Early Puberty Early Causes Puberty Early Causes Adrenarche Puberty Early Causes Thelarche Classification True Hermaphroditism Male Pseudohermaphroditism Female Pseudohermaphroditism Evaluation

34. Klinefelter Syndrome As A Cause Of Infertility Facts about klinefelter syndrome. Causes, chromosomes, diagnosis, infertility,and health considerations. Understanding klinefelter syndrome. http://infertility.about.com/library/ifctr/blkline.htm

zfp=-1 About Infertility Search in this topic on About on the Web in Products Web Hosting Infertility with Apply Now Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects ESSENTIALS Answers to Frequently Asked Questions How Tos Center for Resolutions to Infertility ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Understanding Klinefelter Syndrome A Guide for XXY Males and Their Families WHAT IS KLINEFELTER SYNDROME? In 1942, Dr. Harry Klinefelter and his coworkers at the Massachusetts General Hospital in Boston published a report about nine men who had enlarged breasts, sparse facial and body hair, small testes, and an inability to produce sperm. By the late 1950s, researchers discovered that men with Klinefelter syndrome, as this group of symptoms came to be called, had an extra sex chromosome, XXY instead of the usual male arrangement, XY. (For a more complete explanation of the role this extra chromosome plays, see the accompanying section, " Chromosomes and Klinefelter syndrome In the early 1970s, researchers around the world sought to identify males having the extra chromosome by screening large numbers of newborn babies. One of the largest of these studies, sponsored by the National Institute of Child Health and Human Development (NICHD), checked the chromosomes of more than 40,000 infants.

35. Klinefelter Syndrome - An XXY Legacy (site Being Updated) klinefelter syndrome An XXY Legacy (site being updated). When I was aLittle Lad - Age 10. klinefelter syndrome - An XXY Legacy - My Story. http://www.angelfire.com/wy/XXY/

Klinefelter Syndrome - An XXY Legacy (site being updated) When I was a Little Lad - Age 10 Now I have grown up a bit - age 40 Klinefelter Syndrome - An XXY Legacy - My Story Research into Autism - Too much testosterone in the womb may be a factor People with disabilities have rights too ... XXY International Email Support Group News...News...News...News View My Guestbook Sign My Guestbook Medical Search Web MEDLINE var enabled = 'no'; Related Links: Click to View or Add Links. Hits since November 2000 Email: steph.t@medscape.com

36. HONselect - Klinefelter's Syndrome English Klinefelter's Syndrome, klinefelter syndrome - KlinefeltersSyndrome - Syndrome, Klinefelter's. Français KLINEFELTER, SYNDROME, http://www.hon.ch/HONselect/RareDiseases/C12.740.700.842.454.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Klinefelter's Syndrome - Klinefelter Syndrome - Klinefelters Syndrome - Syndrome, Klinefelter's Français: KLINEFELTER, SYNDROME Deutsch: Klinefelter-Syndrom Español: SINDROME DE KLINEFELTER Português: SINDROME DE KLINEFELTER HONselect ressources Definition: Yes Articles: Yes Images: Yes News: No Conferences: No Clinical trials: Yes Web sites: English Yes Français No Deutsch No Español No Português Yes Home About us Site map ... HONewsletter http://www.hon.ch/HONselect/RareDiseases/C12.740.700.842.454.html Last modified: Thu Jul 25 2002

37. The DRM WebWatcher: Klinefelter Syndrome A Disability Resources Monthly guide to the best online resourcesabout klinefelter syndrome (XXY males). http://www.disabilityresources.org/KLINE.html

Home WebWatcher Regional Librarians ... Contact Us The DRM WebWatcher Klinefelter Syndrome Updated 5/6/2000 A B C D ... About/Hint/Link The approximately 1 in 500 males with Klinefelter syndrome - also known as XXY males - have an extra X chromosome. For information about the effects of XXY or to find support resources, check these sites. Klinefelter Syndrome An overview from the National Organization on Rare Disorders. Klinefelter Syndrome and Associates Information and support services from a nonprofit organization. A page by a parent of a child with XXYY, a very rare variant of Klinefelter syndrome. Klinefelter's Syndrome Club UK General information and links. Klinefelter Syndrome Support Group Home Page Looking for a Klinefelter association, support group, listserv, or e-pal? You're bound to find one on this personal web site. New Zealand Sex Chromosome Society Basic information about Klinefelter syndrome from a charitable trust. Understanding Klinefelter Syndrome An excellent brochure for boys and their families from the National Institute of Child Health and Human Development. Vaughn Hambley's XXY Site This unnamed, personal web site by an individual with XXY is one of the most comprehensive around. There are downloadable articles and documents, a database of people interested in XXY, lots of links (include parenting links and international resources), and much more.

38. Klinefelter Syndrome klinefelter syndrome. This is Klinefelter's syndrome with a 47, XXYkaryotype. A nondysjunctional event in meiosis (maternal or http://medgen.genetics.utah.edu/photographs/pages/klinefelter_syndrome.htm

Klinefelter syndrome view 72 KB version This is Klinefelter's syndrome with a 47, XXY karyotype. A non-dysjunctional event in meiosis (maternal or paternal) left two X chromosomes in an ovum or a sperm. This is relatively common (about 1 in 500 males). Affected males are usually normal, though they may be tall and have small testes. Infertility results from absent sperm. About half have gynecomastia. About 10% of cases are mosaics and are less affected Examinations Photographs Movies Links ... noJava Home

39. Klinefelter Syndrome - Keep Kids Healthy A discussion of the klinefelter syndrome, a cause of mental retardation and delayedpuberty in children with an extra X chromosome. klinefelter syndrome. http://www.keepkidshealthy.com/welcome/conditions/klinefelter.html

Bookstore Site Map Contact Us Help ... Free Web Pages! Search this site: Advanced Search Free Newsletters Main Menu Useful Tools Index of Topics Pediatric Problems New! Parenting Tips Symptom Guide Nutrition Immunizations ... Web Links Online Resources What's New Reviews New! Growth Charts Online Forums Vaccine Schedule Baby Names Guide ... Height Calculator Newsletters: Subscribe to get free news, tips and updates. Recommend Us tell a friend about us or email this page to a friend Main Diseases and Conditions Klinefelter Syndrome Boys normally have 46 chromosomes, including one X and one Y chromosome (46, XY). Girls also have 46 chromosomes, including two X chromosomes (46, XX). Related Topics Gynecomastia School Performance Children with Klinefelter syndrome have one or more extra X chromosomes. It occurs in about 1 out of every 1000 newborn males, and most of these children will have a chromosome complement equal to 47, XXY , although other patterns also exist. Since you must have a Y chromosome to have this disorder, it affects only males. The symptoms of Klinefelters may include a typical body appearance, being

40. Health Information Resource Database: Klinefelter Syndrome And Associates Services.. klinefelter syndrome and Associates. Contact Information.PO Box 119 Roseville, CA 956780119. 916-773-2999 (Voice). Internet http://www.health.gov/NHIC/NHICScripts/Entry.cfm?HRCode=HR2905

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