1. Lipoid Nephrosis Subject lipoid nephrosis Topic Area Urology General Forum The UrologyForum Question Posted By Mieke on Friday, February 20, 1998 . http://www.medhelp.org/perl6/urology/archive/175.html

Advertisement Welcome to Med Help! Questions in The Urology Forum are being answered by doctors from Henry Ford Health System , consistently ranked one of the best hospitals in America. Subject: lipoid nephrosis Topic Area: Urology - General Forum: The Urology Forum Question Posted By: Mieke on Friday, February 20, 1998 Posted by HFHS M.D.-MS on February 24, 1998 at 18:14:28: In Reply to: lipoid nephrosis posted by Mieke on February 20, 1998 at 04:11:09: Is lipoid nephrosis just an older name for minimal change disease? Can it also be called nil disease? I would like to know which term is most frequently used. Dear Mieke; Still hard at work on your thesis I see. I hope you still ask only the easly questions because Nephrology is not my specialty. Lipoid nephrosis is the same as Minimal Change Disease according to our Nephrologist on call. This can also be referred to as "nil disease". This information is provided for general medical education purposes only. Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. Sincerely;

2. EMedicine - Nephrotic Syndrome : Article Excerpt By: Luther Travis, MD Key Words, and Related Terms NS, nephrosis, lipoid nephrosis, primary nephrotic syndrome, PNS, idiopathic nephrotic http://www.emedicine.com/ped/byname/nephrotic-syndrome.htm

(advertisement) Excerpt from Nephrotic Syndrome Synonyms, Key Words, and Related Terms: NS, nephrosis, lipoid nephrosis, primary nephrotic syndrome, PNS, idiopathic nephrotic syndrome, INS, secondary nephrotic syndrome, minimal change nephrotic syndrome, MCNS, minimal lesion nephrotic syndrome, MLNS, nil disease, steroid-sensitive nephrotic syndrome, SSNS, steroid-resistant nephrotic syndrome, SRNS, steroid-dependent nephrotic syndrome, SDNS, mesangial proliferative glomerulonephritis, MPN, immunoglobulin M nephropathy, focal segmental glomerulosclerosis, FSGS, membranoproliferative or mesangiocapillary glomerulonephritis, MPGN, hypocomplementemic glomerulonephritis, membranous glomerulonephritis, MGN, congenital nephrotic syndrome Please click here to view the full topic text: Nephrotic Syndrome Background: The word nephrosis, or what often is called primary nephrotic syndrome (PNS), has its origin in the early part of the 20th century. Nephrosis describes a clinical condition of edema and proteinuria characterized morphologically (light microscopy [LM]) by fatty degeneration of the renal tubules associated with normal glomeruli. The term nephrosis was introduced primarily to distinguish it from nephritis, a term used to denote the clinical condition associated with cellular proliferation of the glomerulus. Shortly thereafter the name of the condition was changed to lipoid nephrosis when it was noted that lipid droplets commonly were found in the urine of affected patients. Lipoid nephrosis gradually evolved to the present name of nephrotic syndrome (NS).

3. THE MERCK MANUAL, Sec. 17, Ch. 224, Glomerular Diseases An in depth look at nephrotic syndrome as well as lipoid nephrosis, focal segmental gomeruloscleroses, HIVassociated nephropathy, and membranous glomerulonephritis. http://www.merck.com/pubs/mmanual/section17/chapter224/224c.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 17. Genitourinary Disorders Chapter 224. Glomerular Diseases Topics [General] Nephritic Syndrome Nephrotic Syndrome Nephrotic Syndrome A predictable complex that results from a severe, prolonged increase in glomerular permeability for protein. Etiology and Classification Nephrotic syndrome (NS) occurs at any age but is more prevalent in children than in adults; in children, it is most common between ages 1 1/2 and 4 yr. There is a predilection for young males, but the sex distribution in older patients is more equal. Proteinuria is thought to occur through functional derangement of two mechanisms: the size-selective barrier leaks large protein molecules, and the charge-selective barrier fails to retain lower mol wt proteins. Diseases causing NS are listed in Table 224-7. Primary causes include minimal change disease, focal segmental glomerulosclerosis (FSGS), membranous glomerulonephritis (MGN), membranoproliferative glomerulonephritis (MPGN), and mesangial proliferative glomerulonephritis (GN). NS can also be due to secondary causes. Symptoms and Signs An early sign of NS is frothy urine due to protein. Other features include anorexia, malaise, puffy eyelids, retinal sheen, abdominal pain, and wasting of muscles. Anasarca with ascites and pleural effusions may occur.

4. Untitled Document Murphy FD, Warfield LM. lipoid nephrosis. Arch Intern Med 1926; 38 449468. BellET. lipoid nephrosis. Am J Pathol 1929; 5 587-622 21. http://www.aspn.it/cameroneng.html

Associazione Siciliana per la Prevenzione e la Terapia delle Nefropatie A.S.P.N. Lettura del Prof. Cameron J Stewart Cameron, Jackie Hicks Renal Unit, Guy's and St Thomas' Hospital King's College, London UK THE ORIGINS AND DEVELOPMENT OF THE CONCEPT OF A "NEPHROTIC SYNDROME" Dropsy, and early descriptions of proteinuria and renal alterations associated with it The cardinal symptom of the nephrotic sydrome is edema, (anasarca, dropsy). During the sixteenth to the mid-eighteenth century the general view was that"dropsy" was a disorder per se, one of the many types of swellings, local and general: physicians did not ask themselves what the "cause" of a dropsy might be; the patient "had" a dropsy. Thus when Samuel Johnson died dropsical in 1784 there was no speculation as to its "origin", and the fact that his kidneys were grossly diseased was noted only incidentally at the post mortem. This contemporary attitude to dropsy makes the observations of the early paediatrician Theodor Zwinger (1658-1724) of Basel, Switzerland in 1722 all the more remarkable, in that he unequivocally attributed the condition to disease in the renal tubules [1,2] since in paediatric practice, liver and heart disease would rarely have been present as causes of generalised edema.

5. Lipoid Nephrosis lipoid nephrosis. Nephrotic syndrome. Electron micrograph.Previous Next 1 2 3 4 5 Return to Systemic Pathology Page. http://biomed.brown.edu/Courses/BI279/Lec09/Lec09-D.htm

Lipoid Nephrosis Nephrotic syndrome. Electron micrograph. Previous Next Return to Systemic Pathology Page

6. 072ALipoid Nephrosis (low) lipoid nephrosis (low) Glomeruli are normal on light microscopic examination capillary loops are open with delicate walls, the mesangium is not hypercellular ( no more than 3 mesangial cells between capillaries ) or expanded. http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072A.html

Lipoid Nephrosis (low) Glomeruli are normal on light microscopic examination - capillary loops are open with delicate walls, the mesangium is not hypercellular ( no more than 3 mesangial cells between capillaries ) or expanded. click here to see a larger version of this image in a new browser window. Johns Hopkins School Of Medicine Department of Pathology Office of Academic Computing LectureLinks

7. 072BLipoid Nephrosis (high) lipoid nephrosis (high) Proximal tubular cells show fine vacuolisation ( bubbly cytoplasm ) these are lipid droplets, reflecting lipiduria which in turn is secondary to hyperlipidemia. http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072B.html

Lipoid Nephrosis (high) Proximal tubular cells show fine vacuolisation ( bubbly cytoplasm ) -these are lipid droplets, reflecting lipiduria which in turn is secondary to hyperlipidemia. click here to see a larger version of this image in a new browser window. Johns Hopkins School Of Medicine Department of Pathology Office of Academic Computing LectureLinks

8. Lipoid Nephrosis Subject lipoid nephrosis Forum The Urology Forum Topic Area Postedby Mieke on February 20, 1998 at 041109 Is lipoid nephrosis http://www.medhelp.org/perl6/urology/archive/146.html

Advertisement Welcome to Med Help! Questions in The Urology Forum are being answered by doctors from Henry Ford Health System , consistently ranked one of the best hospitals in America. Subject: lipoid nephrosis Forum: The Urology Forum Topic Area: Posted by Mieke on February 20, 1998 at 04:11:09: Is lipoid nephrosis just an older name for minimal change disease? Can it also be called nil disease? I would like to know which term is most frequently used. Ask A Question The Urology Forum Urology Forum Archives Med Help Home Information contained within this forum is intended solely for general educational purposes and is not intended nor implied to be a substitute for professional medical advice relative to your specific medical condition or question. Always seek the advice of your physician or other health provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this site you agree to the following Terms and Conditions Med Help International

9. Lipoid Nephrosis Medical Encyclopdia article about lipoid nephrosis A resource with information on over 4000 medical topics including lipoid nephrosis http://www.marylandadd.com/medical-terms/01322.htm

Lipoid nephrosis A Medical Encyclopedia Article provided by Maryland General Hospital A resource with information on over 4000 medical topics including: Lipoid nephrosis Previous Next

10. Lipoid Nephrosis - General Practice Notebook lipoid nephrosis. Minimal change nephropathy is responsible for 90% ofthe cases of nephrotic syndrome in children less than 5 years of age. http://www.gpnotebook.co.uk/cache/355794967.htm

lipoid nephrosis Minimal change nephropathy is responsible for 90% of the cases of nephrotic syndrome in children less than 5 years of age. It also occurs in adults - approx 20%. The name is derived from the fact that the only detectable abnormality histologically is fusion and deformity of the foot processes under the electron microscope. Both light microscopy and immunofluorescence are unremarkable. The condition is most frequent in children aged between two and four years. It has been suggested that MCD is more common in atopic patients, especially those posessing HLA-DR7. However, a direct link between allergic sensitisation and the onset of MCD is yet to be established. MCD is steroid-responsive and, in general, does not lead to chronic renal failure. Click here for more information...

11. LIPOID NEPHROSIS lipoid nephrosis A disorder of the kidneys which largely affectsthe glomerulus, the blood filtering structure. This disorder http://www.mymedadvice.com/html/5/gls_2920.htm

LIPOID NEPHROSIS - A disorder of the kidneys which largely affects the glomerulus , the blood filtering structure. This disorder is one common cause of nephrotic syndrome in children affecting 2 to 3 children per 100,000 population under age 16 in the US. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. Risk factors include a history for a immune disorder, recent immunization, or a bee sting. Diagnosis is made by renal biopsy . Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented.

12. Lipoid Nephrosis The Urology Forum ask the doctor medical forum for patients hosted by Med Help Intl. Is lipoid nephrosis just an older name for minimal change disease? http://www.medhelp.org/forums/urology/archive/146.html

Advertisement Welcome to Med Help! Questions in The Urology Forum are being answered by doctors from Henry Ford Health System , consistently ranked one of the best hospitals in America. Subject: lipoid nephrosis Forum: The Urology Forum Topic Area: Posted by Mieke on February 20, 1998 at 04:11:09: Is lipoid nephrosis just an older name for minimal change disease? Can it also be called nil disease? I would like to know which term is most frequently used. Ask A Question The Urology Forum Urology Forum Archives Med Help Home Information contained within this forum is intended solely for general educational purposes and is not intended nor implied to be a substitute for professional medical advice relative to your specific medical condition or question. Always seek the advice of your physician or other health provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this site you agree to the following Terms and Conditions Med Help International

13. DSHI Systems - Medical Glossary LIGAMENTS; LINIMENT; LIPEMIA; LIPODYSTROPHY; lipoid nephrosis; LIPOLYSIS;LIPOMA; LIPOPROTEINS; LIPOSITOL; LIPOSUCTION; LITHOTRIPSY; LIVER; http://www.mymedadvice.com/html/L_list.htm

LABOR LABYRINTHITIS LACERATE LACERATION LABOR LABYRINTHITIS LACERATE LACERATION ... LYTES PROFILE

14. Lipoid Nephrosis lipoid nephrosis Nephrotic syndrome. Electron micrograph. Previous Next 1 2 3 4 5 Return to Systemic Pathology Page http://biomed.brown.edu/courses/BI279/Lec09/Lec09-D.htm

Lipoid Nephrosis Nephrotic syndrome. Electron micrograph. Previous Next Return to Systemic Pathology Page

15. 072A Lipoid Nephrosis (low) lipoid nephrosis (low), 072A. Glomeruli are normal on light microscopicexamination capillary loops are open with delicate walls http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072A_Full.html

Lipoid Nephrosis (low) Glomeruli are normal on light microscopic examination - capillary loops are open with delicate walls, the mesangium is not hypercellular ( no more than 3 mesangial cells between capillaries ) or expanded. Johns Hopkins School Of Medicine Department of Pathology Office of Academic Computing LectureLinks

16. 072B Lipoid Nephrosis (high) lipoid nephrosis (high), 072B. Proximal tubular cells show fine vacuolisation( bubbly cytoplasm ) these are lipid droplets, reflecting http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072B_Full.html

Lipoid Nephrosis (high) Proximal tubular cells show fine vacuolisation ( bubbly cytoplasm ) -these are lipid droplets, reflecting lipiduria which in turn is secondary to hyperlipidemia. Johns Hopkins School Of Medicine Department of Pathology Office of Academic Computing LectureLinks

17. Lipoid Nephrosis lipoid nephrosis. TREATMENT steroids; antibiotics; cyclophosphamide; chlorambucil.ICD9-CM 581.3 lipoid nephrosis Date last updated 9/11/01 http://www.5mcc.com/Assets/SUMMARY/0540.html

18. Minimal Change Disease Minimal change nephrotic syndrome; Nil disease; lipoid nephrosis; Idiopathicnephrotic syndrome of childhood. Causes, incidence, and risk factors http://www.pennhealth.com/ency/article/000496.htm

Disease Injury Nutrition Poison ... Prevention Minimal change disease Definition: A disorder of the kidneys that affects the structures (glomeruli) which include small capillaries surrounded by membranes through which the blood is filtered to form urine. Alternative Names: Minimal change nephrotic syndrome; Nil disease; Lipoid nephrosis; Idiopathic nephrotic syndrome of childhood Causes, incidence, and risk factors: Minimal change disease is one cause of nephrotic syndrome . It is named because under a light microscope the glomeruli appear totally normal. Under an electron microscope characteristic changes in the glomeruli can be seen, including the fusion of a portion of the epithelial layer. Minimal change disease is most common in children but occasionally occurs in adults. The cause is unknown, but the disease may be preceded by viral infection, allergic reactions or recent immunizations. Minimal change disease does not reduce the amount of urine produced. It rarely progresses to renal failure Review Date: 12/2/2001 Reviewed By: Andrew Koren, M.D., Department of Nephrology, NYU-Mount Sinai Medical Center, New York, NY. Review provided by VeriMed Healthcare Network.

19. ICD-9-CM 580 Foot process disease. lipoid nephrosis. Minimal change http://www.tpmm.com/services/ICD9/1tabular580.html

NEPHRITIS, NEPHROTIC SYNDROME, AND NEPHROSIS (580-589) Excludes: hypertensive renal disease (403.00-403.91) 580 Acute glomerulonephritis Includes: acute nephritis 580.0 With lesion of proliferative glomerulonephritis Acute (diffuse) proliferative glomerulonephritis Acute poststreptococcal glomerulonephritis 580.4 With lesion of rapidly progressive glomerulonephritis Acute nephritis with lesion of necrotizing glomerulitis 580.8 With other specified pathological lesion in kidney 580.81 Acute glomerulonephritis in diseases classified elsewhere Code first underlying disease, as: infectious hepatitis (070.0-070.9) mumps (072.79) subacute bacterial endocarditis (421.0) typhoid fever (002.0) 580.89 Other Glomerulonephritis, acute, with lesion of: exudative nephritis interstitial (diffuse) (focal) nephritis 580.9 Acute glomerulonephritis with unspecified pathological lesion in kidney Glomerulonephritis: specified as acute NOS specified as acute hemorrhagic specified as acute Nephritis specified as acute Nephropathy specified as acute 581 Nephrotic syndrome 581.0 With lesion of proliferative glomerulonephritis

20. Disease Reference pubic Lichen planus Lichen simplex chronicus Limbgirdle muscular dystrophies LipidDisorders - acquired Lipofuscinosis lipoid nephrosis Listeriosis Little http://www.pennhealth.com/ency/index/diseidxl.htm

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