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         Meige Syndrome:     more detail

81. Dr. Donohue: 5/17/99
Dystonias cause muscle contractions. Dear Dr. Donohue I have meige's syndrome. DB meige's syndrome is a member of the dystonia family of illnesses.
http://www.s-t.com/daily/05-99/05-17-99/zzzaddon.htm
Dr. Donohue
Dystonias cause muscle contractions
Dear Dr. Donohue: I have Meige's syndrome. Can you give me any information about it? Is it a hereditary illness?
D.B.
Meige's syndrome is a member of the dystonia family of illnesses. Dystonias cause abrupt muscle contractions, pulling the affected body part into an abnormal and sometimes painful position.
In the Meige's variety of dystonia, the involved muscles are the chewing muscles, the muscles encircling the eyes and the tongue muscles. Sustained eyelid closing, opening and closing of the mouth like a spring trap, and protrusion of the tongue from the mouth are prominent symptoms.
Inheritance has a hand in some dystonias. Whether it figures into Meige's syndrome is an issue yet to be proven. Dystonia can follow on the heels of a head injury or a stroke. For many, however, a precipitating cause cannot be found.
Drugs such as baclofen and trihexyphenidyl might ease Meige's syndrome. Botulinum toxin injected into muscles can stop the sudden muscle contractions of dystonia. Botulinum toxin comes from the bacterium that causes serious food poisoning and muscle paralysis. The toxin is watered down to a point where it does not paralyze, but does stop involuntary muscle contractions.
Whether you know it or not, you have a dedicated friend in the form of the Dystonia Medical Research Foundation. The foundation keeps its members informed of the latest therapies and sorts out the fancy from the facts of dystonic illnesses. The toll-free number is (800) 377-3978.

82. Marijuana And Tourette's Syndrome
8. Philadelphia Lippincott, 1981 81104. 7. Snider SF, Consroe P. Treatmentof meige's syndrome with cannabidiol. Neurology 1984; 34 (Suppl) 147.
http://www.druglibrary.org/schaffer/hemp/medical/mjtouret.htm
Sign the Resolution for a Federal Commission on Drug Policy Contents Feedback Search ... Medical Information MARIJUANA AND TOURETTE'S SYNDROME Journal of Clinical Psychopharmacology, Vol. 8/No. 6, Dec 1988 Editors: Although a variety of pharmacological agents have been reported to attenuate symptoms of Tourette's syndrome (TS), the pathophysiology of this disorder remains unknown. Apart from the presence of disabling motor and vocal tics, TS patients often experience behavioral disturbances including obsessive compulsive thoughts, anxiety, depression, abnormal sleep disturbances. (1) Drug abuse to obtain relief from the chronic anxiety may be common among these patients. (2) (3) We recently encountered three patients with TS who experienced incomplete responses to conventional anti-TS drugs but noted a significant amelioration of symptoms when smoking marijuana. The first patient was a 15-year-old boy who, in addition to motor tics, had obsessive compulsive and self-mutilatory behavior improved with administration of imipramine (37.5 mg/day) combined with the oral opiate

83. Spears & MacLeod: Medical Links: Spasm: Pharmasave :Yarmouth, Nova Scotia : Gras
11. Hemifacial Spasm (meige's syndrome Hemifacial Spasm (meige's syndrome)(alsocalled Essential Blepharospasm) Hemifacial spasms or meige's syndrome.
http://www.spearsmacleod.com/links/s/spasm/
Spasm: is an involuntary and abnormal violent contraction of muscles or muscle tissue. Tonic spasm, or cramp, is characterized by an unusually prolonged and strong muscular contraction, with relaxation taking place slowly.
MediLinks.. Spasm
www.spearsmacleod.com
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84. Roche Lexikon Medizin (4. Aufl.) - Meige* Syndrom
Translate this page Mei ge* Syndrom. engl. meige's syndrome. su NONNE*-MILROY*-meige*.Verwandte Themen. Nonne* Syndrom. Roche Lexikon Medizin, 4.Auflage
http://www.gesundheit.de/roche/ro22500/r24209.html
Mei ge* Syndrom engl.: Meige's syndrome
s.u. N ONNE *-M ILROY ... EIGE
Verwandte Themen Nonne* Syndrom

85. Tourette Syndrome And Other Tic Disorders
In older individuals, conditions such as Wilson's disease, tardive dyskinesia, meige'ssyndrome, chronic amphetamine abuse, and the stereotypical movements of
http://www.geocities.com/Hollywood/2219/diag.html
Tourette Syndrome and Other Tic Disorders
Definitions of Tic Disorders
Tics are involuntary, rapid, repetitive and stereotyped movements of individual muscle groups. They are more easily recognized than precisely defined. Tic disorders are generally categorized according to age of onset, duration of symptoms, severity of symptoms and the presence of vocal and/or motor tics.
Transient tic disorders often begin during the early school years and can occur in up to 18% of all children. Common tics include eye blinking, nose puckering, grimacing and squinting. Transient vocalizatins are less common and include various throat sounds, pinching the genitals are examples. Transient tics last only a few weeks or months and are usually not associated with specific behavioral or school problems. They are especially noticeable during times of heightened excitement or fatigue. As with all tic syndromes, boys are three to four times more often affected than girls. While transient tics by definition do not persist for more than a year, it is not uncommon for a child to have recurrent episodes of transient tics over the course of several years.
Chronic tic disorders are differentiated from transient tic disorders not only by their duration over many years, but by their relatively unchanging character. While transient tics come and go (sniffing may be replaced by forehead furrowing and the furrowing and furrowing may become finger snapping), chronic ticssuch as facial contortions or blinkingmay persist unchanged for years.

86. Week 1
Mindy Loterstein. Sam Cohen. Week 2. Refsum Disease. Mindy Loterstein. Sam Cohen.Rifi Rosen Week 3. meige's syndrome. Rifi Rosen. Week 4. CharcotMarieTooth Disorder.
http://www.geocities.com/Athens/3670/winners.html
Week 1
Methemoglobinemia
  • Mindy Loterstein
  • Laura Elkayam
  • Issac Dayan
  • Jeremy Bressman
    Week 2
    Beluga Whale
  • Jeremy Bressman
  • Laura Elkayam
  • Isaac Dayan
    Week 3
    Kuru
  • Jeremy Bressman
  • Laura Elkayam
  • Isaac Dayan
  • Mindy Loterstein
    Week 4
    Angelman's Syndrome
  • Jeremy Bressman
  • Laura Elkayam
  • Isaac Dayan
  • Shira Reich
    Week 5
    Familial Mediterranean Fever
  • Jeremy Bressman
  • Laura Elkayam
  • Mindy Loterstein
  • Isaac Dayan
    Week 6
    Shistosomiasis
  • Jeremy Bressman
  • Laura Elkayam
  • Isaac Dayan
    Week 7
    Dystonia
  • Jeremy Bressman
  • Laura Elkayam
  • Isaac Dayan
  • Mindy Loterstein
    Week 8
    Sin Nombre Virus (however I accepted Hantavirus. Sin Nombre is a varaiation of the Hanta virus)
  • Laura Elkayam
  • Jeremy Bressman
  • Ruth Balinsky
  • Rifi Rosen
  • Mindy Loterstein
  • Issac Dayan
  • Dr. Phllip Rosen
    Week 9
    Brown Recluse Spider
  • Laura Elkayam
  • Issac Dayan
  • Jeremy Bressman
  • Mindy Loterstein
  • Issac Dayan
  • Dr. Phllip Rosen
    Week 10
    The Nine Banded Armadillo Laura Elkayam Dr. Phllip Rosen Rifi Rosen Jeremy Bressman Issac Dayan Ari Lebowicz
    Week 11
    Usher Syndrome Jeremy Bressman Issac Dayan Rifi Rosen Adina Weintraub Laura Elkayam Dr. Phllip Rosen
  • 87. Parkinson's Disease Center And Movement Disorders Clinic
    Although the eponym meige's syndrome has been sometimes used to designate idiopathiccranialcervical dystonia, this term is not appropriate because Talkow
    http://www.bcm.tmc.edu/neurol/jankovic/educ_blepharospasm.htm
    Parkinson's Disease Center
    and Movement Disorders Clinic Blepharospasm
    Joseph Jankovic, M.D.

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    What and How Next Download Summary ( Printer-Friendly)
    REFERENCES
    • Ozelius LJ, Hewett JW, Page CE, et al. The early onset torsion dystonia gene [DYT1] encodes an ATP-binding protein. Nature Genet 1997;17:40-48. Cardoso F, Jankovic J. Blepharospasm. In: Tsui J, Calne DB, eds. Handbook of Dystonia, Marcel Dekker, New York, NY, 1995:129-141. Jankovic J, Schwartz K. Longitudinal experience with botulinum toxin injections for treatment of blepharospasm and cervical dystonia. Neurology 1993;43:834-836. Jankovic J, Nutt JG. Blepharospasm and cranial-cervical dystonia (Meige's syndrome): familial occurence. In: Jankovic J, Tolosa E, eds. Facial Dyskinesias. Advances in Neurology. vol. 49. Raven Press, New York, 1988:117-123.

    88. Classification Of Laryngeal Dystonias
    structures besides the larynx), or nonfocal (involvement of other structures/systems,such as the tongue, palate, or pharynx (eg, meige's syndrome) or even
    http://www.bgsm.edu/voice/class_ld.html
    you are here: home voice
    Classification of Laryngeal Dystonias
    J.A. Koufman, MD, and P. David Blalock, MA At The Center For Voice Disorders of Wake Forest University , one hundred consecutive patients with "spasmodic dysphonia" were systematically evaluated and classified by criteria described below. The classification herein presented at first appears complex; however, in clinical practice, it appears to be a useful system in diagnosis, in predicting the response to Botox treatment, and in customizing the treatment for each SD subtype. Materials and Methods
    All patients underwent otolaryngologic examination and videoendoscopic assessment of laryngeal function by an otolaryngologist, evaluation by a speech pathologist specifically trained in the diagnosis and management of voice disorders, voice laboratory evaluation, screening neurological examination, and laryngeal electromyography (EMG). The otolaryngologic evaluation comprised: 1) a detailed medical history, including completion of a standardized laryngeal movement disorders data flow sheet; 2) a complete otolaryngologic examination; 3) transnasal fiberoptic laryngoscopy (TFL) with videostroboscopy using a standardized format that included asking the patient to perform the following vocal tasks twice, once using a normal glottal attack and once using a soft breathy voice. The tasks were for the patient to state his or her name, the date, the vowels /i/ and /a/, and a standard phrase, "the cake is great, and the rainbow is beautiful."

    89. Neurosurgical Terms M
    Medulla. Top. Medulloblastoma. Mega cisterna magna. Megalencephaly. meige'ssyndrome. Melatonin. Meniere's disease. Meninges. Meningioma. Meningioma, complex.
    http://uscneurosurgery.com/glossary/terms plain english m.htm
    A B C D ... Z M MLF (Medial longitudinal fasciculus) MRI (Magnetic resonance imaging) MS (Multiple sclerosis) MTS (Mesial temporal sclerosis) ... McConnell's artery MEAN Mebendazole Mechanical ventilation Mechanoreceptor Meckel's ... Myofasciitis M Return to uscneurosurgery.com Homepage

    90. Sulpiride In Meige's Syndrome:Possible Role Of Glutamate
    Sulpiride in meige's syndromePossible role of glutamate Sang Ahm Lee,MD., Jin Soo Kim, MD., Jae Hoon Ahn, MD., Kyoung Gyu Choi, MD.
    http://www.amc.seoul.kr/~salee/a_sulpiride.htm
    Sulpiride in Meige's syndrome:Possible role of glutamate Sang Ahm Lee, MD., Jin Soo Kim, MD., Jae Hoon Ahn, MD., Kyoung Gyu Choi, MD. Department of Neurology, Yonsei University College of Medicine Sulpiride, selective antagonist for adenylate cyclase-independent dopamine receptor, was administrated to 25 patients with blepharospasm and oromandibular dystonia (Meige's syndrome). Of the 25 patients, 7 patients (28%) produced marked and lasting improvement with sulpiride and 12 patients (48%) showed mild or transient improvement. This favorable therapeutic response to sulpiride suggests that striatal glutamate underactivity may play a role in the pathophysiology of Meige's syndrome as a primary or secondary defect. Yonsei Medical Journal 1988;29:62-65.

    91. DMRF: Forms Of Dystonia: Oromandibular Dystonia
    When oromandibular is combined with blepharospasm, it may be referred to as meige'sSyndrome named after Henry meige, the French neurologist who first
    http://www.dystonia-foundation.org/defined/oro.asp
    To view specific content on this page, click on a category above. Oromandibular Cable/T1 (Get RealPlayer)
    What is it?
    Oromandibular dystonia is a focal dystonia characterized by forceful contractions of the jaw and tongue causing difficulty in opening and closing the mouth and often affecting chewing and speech.
    Back to top
    Symptoms
    Oromandibular is often associated with dystonia of the cervical muscles (cervical dystonia/spasmodic torticollis), eyelids (blepharospasm), or larynx (spasmodic Dysphonia). The combination of upper and lower dystonia is sometimes called cranial-cervical dystonia. When oromandibular is combined with blepharospasm, it may be referred to as Meige's Syndrome named after Henry Meige, the French neurologist who first described the symptoms in detail in 1910. The symptoms usually begin between the ages of 40 and 70 years old and appear to be more common in women than in men. Oromandibular dystonia may be a continuous disorder that persists even during sleep, or it may be task-specific, occurring only during activities such as speaking or chewing. Difficulty in swallowing is a common aspect of oromandibular dystonia if the jaw if affected, and spasms in the tongue can also make it difficult to swallow.

    92. The Health Library — Dental And Oral Health
    Oromandibular DystoniaDystonia Medical Research Foundation. meige's SyndromeOhioState University Medical Center. Mouth Diseases, Mouth DisordersMEDLINEplus.
    http://healthlibrary.stanford.edu/resources/internet/bodysystems/dentistry.html
    Diseases and Disorders Use these links to jump directly to your topic of interest:
    Dental Anatomy Dental Care Dental Procedures Fluoride ... Tooth Replacement Dental and Oral Health: Page 2 Page 3 General Dental and Oral Health Organizations American Academy of Periodontology American Association of Oral and Maxillofacial Surgeons (AAOMS) American Dental Association National Institute of Dental and Craniofacial Research (NIDCR) Overviews Mouth and Teeth Topics:MEDLINEplus Dental Health:MEDLINEplus Understanding Dental Health:netLibrary Oral Health Topics:American Dental Association ... Bond's Book of Oral Diseases, 4th Edition:Maxillofacial Center for Diagnostics and Research Cancer Treatment and Oral Health See Cancer, Coping With Cancer and Its Treatment Dental Anatomy Atlas of theBody: The Teeth:American Medical Association Types of Teeth:University of Pennsylvania Parts of Your Teeth and Gums:University of Pennsylvania Surfaces of the Tooth:University of Pennsylvania ... Permanent Teeth Eruption Chart:American Dental Association Jaw Diseases TMD/TMJ Temporomandibular Joint Dysfunction:MEDLINEplus TMD/TMJ (Jaw Disorders):National Women's Health Information Center Temporomandibular Disorders:NIDCR Temporomandibular Joint Disorder (TMJ):MedicineNet Dystonia of the Jaw Oromandibular Dystonia:Dystonia Medical Research Foundation Meige's Syndrome:Ohio State University Medical Center Mouth Diseases Mouth Disorders:MEDLINEplus Mouth Problems, Self-Care Flow Chart:American Academy of Family Physicians

    93. Open Label Evaluation Of Cannabidiol In Dystonic Movement Disorders (Internation
    In light of the above, we initiated an open trial of CBD in a patient with meige'ssyndrome (Blepharospasmoromandibbular dystonia) (Snider Consroe, 1984
    http://www.thecompassionclub.org/library/movement.html
    Open label evaluation of cannabidiol in dystonic movement disorders
    International Journal of Neuroscience , 1986, Vol. 30, pp. 277-282 By Paul Consroe, Reuven Sandyk and Stuart R. Snider
    Department of Pharmacology and Toxicology, and Neurology University of Arizona Medical Center, Tucson, Arizona 85721, U.S.A.
    Cannabidiol (CBD) a nonpsychoactive cannabinoid of Cannabis, was given to 5 patients with dystonic movement disorders in a preliminary open pilot study. Oral doses of CBD rising from 100 t 600 mg/day over a 6 week period were administered along with standard medication. Dose-related improvement in dystonia was observed in all patients and ranged from 20 to 50%. Side-effects of CBD were mild and included hypotension, dry mouth, psychomotor slowing, lightheadedness, and sedation. In 2 patients with coexisting Parkinsonian features, CBD at doses over 300 mg/day exacerbated the hypokinesia and resting tremor. CBD appears to have antidystonic and Parkinsonism-aggravating effects in humans. As early as 1842, O'Shaughnessy reported that oral Cannabis blocked tetanic convulsions and reduced muscular spasms in his patients afflicted with epilepsy, tetanus or rabies, while in 1890 Reynolds claimed that oral Cannabis was useful in the management of "choreoid and epileptoid clonic spasms." During the latter 19th century, Cannabis was commonly employed as a general antispasmodic agent, and several recent reports appear to provide some justification for this use. In 1981, Petro and Ellenberger reported that delta-9-tetrahydrocannabinol (THC), the major psychoactive cannabinoid of Cannabis, reduced spasticity of multiple sclerosis, and in 1983 Cliffored reported that THC reduced tremor in a few patients with the same disease. Also in 1980 Cunha et al. reported that cannabidiol (CBD), a major nonpsychoactive cannabinoid of Cannabis, prevented convulsions in epileptic patients who were largely refractory to standard antiepileptic drugs.

    94. Facial Muscles Spasms: An Australian Study (updated: Apr 29, 2001)
    Purpose A group of patients suffering from blepharospasm, hemifacial spasm, andMeige's syndrome were surveyed to determine the delay from the onset of their
    http://hemifacialspasm.org/cof/mipa07.shtml
    Home page Site map Medical information Experiences Members Communication Medical information ... HFS Published articles Facial muscles spasms: An Australian study Note: this document was manually transcribed - any errors are ours Article: Facial muscles spasms: An Australian study authors: Lionel Kowal, MB BS, FRACO, FRACS , Roger Davies, MB BS, FRACO and Patricia M Kiely, PhD Ocular Motility Clinic and Orbital Plastics and Lacrimal [OPAL] Clinic, Royal Victorian Eye and Ear Hospital, Private Eye Clinic, East Melbourne and Department of Ophthalmology, The University of Melbourne, Parkville, Victoria, Australia source: Australian and New Zealand Journal of Ophthalmology (1998) 26, 123-128
    Abstract
    Purpose: A group of patients suffering from blepharospasm, hemifacial spasm, and Meige's syndrome were surveyed to determine the delay from the onset of their condition until a correct diagnosis was reached, the attitudes of practitioners towards them and their condition, the effect of their condition on their lifestyle and the effect of different types of treatment on their conditions. Methods: Questionnaires were offered to all patients with blepharospasm, hemifacial spasm, and Meige's syndrome presenting to three ophthalmologists licensed to treat patients with botulinum toxin injections over a 12 month period.

    95. Katalog - Wirtualna Polska
    Serwis Katalog w Wirtualna Polska S.A. pierwszy portal w Polsce.
    http://katalog.wp.pl/DMOZ/Health/Conditions_and_Diseases/Neurological_Disorders/
    Poczta Czat SMS Pomoc Szukaj.wp.pl: -Katalog -Polskie www -¦wiatowe www -Wirtualna Polska -FTP/Pliki -Grupy dyskusyjne -Encyklopedia -Produkty wp.pl Katalog Katalog ¦wiatowy DMOZ ... Brain Diseases > Basal Ganglia Fakty o Katalogu Pomoc Regulamin Serwis szukaj ... Ostatnio dodane
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    96. ’ጌ“œ‚ð‹N‚±‚µ‚â‚·‚¢–òÜ
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    http://www.sam.hi-ho.ne.jp/tootake/199361.html
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    97. õˆømMn
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    http://www.so-net.ne.jp/medipro/hypref/hyper/index/m.html
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    Machado-Joseph disease
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    macrothrombocytic thrombopathia
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    magnesium
    magnetic field disturbance
    Ž¥êáŠQ [’†“ŁEŠÂ‹«]
    MAHC
    ˆ««Žîᇐ”º«‚CaŒŒÇ
    malabsorption syndrome
    ‹zŽû•s—ǏnjóŒQ
    malaria
    Malayan filariasis
    ‘gDŠñ¶ü’ŽÇ
    male hypergonadism
    male hypogonadism
    malignancy associated hypercalcemia
    ˆ««Žîᇐ”º«‚CaŒŒÇ
    malignant hepatoma
    ŠÌ×–EŠà [ŠÌE’_EäX]
    malignant histiocytosis
    ˆ««‘gD‹…Ç [ŒŒ‰t]
    malignant hypertension
    [tE”A˜H]
    malignant limb-girdle muscular dystrophy
    is«‹ØƒWƒXƒgƒƒtƒB[ [_Œo]
    malignant rheumatoid arthritis
    [–ƉuƒAƒŒƒ‹ƒM[]
    malignant syndrome
    §“f–ò’†“Å [_Œo]
    ƒtƒFƒmƒ`ƒAƒWƒ“ŒnŒü¸_–ò’†“Å [_Œo]
    malignant tumor
    [tE”A˜H]
    malignant tumor of the small intestine
    Mallory-Weiss syndrome
    Mallory-WeissÇŒóŒQ
    Mallory-WeissÇŒóŒQ
    Mallory-WeissÇŒóŒQ
    malnutrition-related DM
    “œ”A•a
    manganase poisoning
    [’†“ŁEŠÂ‹«]
    MAO
    ƒ‚ƒmƒAƒ~ƒ“ƒIƒLƒVƒ_[ƒ[
    Marburg disease
    Marburg virus disease
    march hemoglobinuria
    ÔŒŒ‹…‹@ŠB“IáŠQ«—nŒŒ«•nŒŒ [ŒŒ‰t]
    Marchiafava-Bignami disease
    Marchiafava-BignamiÇŒóŒQ [_Œo]
    Marchiafava-Bignami syndrome
    Marchiafava-BignamiÇŒóŒQ [_Œo]
    Marchiafava-BignamiÇŒóŒQ
    Marchiafava-BignamiÇŒóŒQ [_Œo]
    Marchiafava-Micheli syndrome
    ”­ì«–éŠÔƒwƒ‚ƒOƒƒrƒ“”AÇ [ŒŒ‰t]
    Marfan's syndrome
    MarfanÇŒóŒQ [–ƉuƒAƒŒƒ‹ƒM[]
    MarfanÇŒóŒQ
    MarfanÇŒóŒQ [–ƉuƒAƒŒƒ‹ƒM[]
    marginal abscess

    98. OMRF Research Studies
    Biomembranes, BiPolar (Mental Health). Birth Defects, Blepharospasm (MeigeSyndrome). Blood Disease, Bone Cancer. Bone Disease, Bone Marrow Transplants.
    http://www.omrf.org/OMRF/Admin/Development/ResearchStudies.asp

    Current Research Studies
    Achalasia Addison's Disease Aging ADHD AIDS ALS (Lou Gehrig's Disease) Alcholism Allergies Alzheimer's Disease American Indian Children Amyloidosis Anemia Aneurysm Antiobiotic Resistance (Mechanisms) Aplastic Anemia APL Arteriosclerosis Arthritis Asthma Ataxia Atherosclerosis Autism Autoimmune Disease Bell's Palsy Biomembranes Bi-Polar (Mental Health) Birth Defects Blepharospasm
    (Meige Syndrome) Blood Disease Bone Cancer Bone Disease Bone Marrow Transplants Brain Diseases Brain Tumor Breast Cancer Bulimia Cancer Cardiovascular (CVA) Cerebral Hemorrhage Cerebral Palsy Cerebral Vascular Disease Charcot Marie Tooth Disease Children's Disease Fund Chronic Fatigue Immune Def. (CFIDS) Clinical Pharmacology Colon COPD - Chronic Obstr. Pulmonary Disease Cortico Basal Ganglionic Degeneration Crest Syndrome Creutzfeldt-Jakob Syndrome Crohn's Disease (Ileitus) Crystallography Cushing Syndrome Cystic Fibrosis Cystinosis Cytomegalovirus Dementia Depression Dermatomyositis Diabetes Diffuse Lewybody Disease Down's Syndrome Dystonia Emphysema Epilepsy Familial Tremors / Essential Tremors Fibromyalgia Flesh Eating Disease (Antiobiotic Resistance) Gastric Ulcer Gastrointestinal Gaucher's Disease General Research Genetics George Garrison Pediatric Research Geriatrics Goodpasture Syndrome Graves Disease Guilain-Barre Syndrome Hardening of Arteries Head Trauma Heart Heart By-pass Surgery Hematology Hemophilia Hepatitis/Hepatitis C Hodgkins Disease Huntington's Chorea

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