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  1. Melorheostosis: Webster's Timeline History, 1950 - 2007 by Icon Group International, 2010-03-10

21. BORG Collective : Case 12: Possible Melorheostosis, L1-L2 Posterior Elements
Case 12 Possible melorheostosis, L1L2 posterior elements. (Answer wedon't know. maybe melorheostosis?). BORG Case List. Discuss this page.
http://gillespy.rad.washington.edu:8080/borg/stories/storyReader$196

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Case 12: Possible melorheostosis, L1-L2 posterior elements
print-friendly version Mail This Story Fri, Jan 31, 2003; by John Hunter.
From Mike Tuite, MD, University of Wisconsin:
18 year old male with 1-2 years of back pain, now can no longer work at his construction job. No fever or WBC. Minimal relief with nonsteroidals, pain not any worse at night. Did get short term relief with a right L12 facet joint injection with steroid/bupivicaine. (Answer: we don't know. maybe melorheostosis?) BORG Case List Discuss this page
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Last update: Monday, February 3, 2003 at 1:18:37 AM Pacific.

22. BORG Collective : Case 12: Possible Melorheostosis, L1-L2 Posterior Elements
Case 12 Possible melorheostosis, L1L2 posterior elements. print-friendlyversion . (Answer we don't know. maybe melorheostosis?). BORG Case List.
http://gillespy.rad.washington.edu:8080/borg/discuss/msgReader$196?mode=topic

23. ORPHANET® : Melorheostosis
Translate this page ORPHANET. ORPHANET database access. melorheostosis.Direct access to details Alias Home Page.
http://www.orpha.net/static/GB/melorheostosis.html
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24. Error Page
DISEASE melorheostosis, CIM Q82.8, melorheostosis is a rare form of hyperostosisof long bones, which rarely affects the spine, the ribs or the skull.
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=2485

25. Melorheostosis : Meddie Health Search
birth but grew steadily after birth. The suggested diagnosis is melorheostosis.(Rating 0.00 Votes 0) Rate It. Information on melorheostosis
http://www.meddie.com/search/Health/Conditions_and_Diseases/Rare_Disorders/Melor
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Search Meddie: the entire directory only this category More search options Home Health Conditions and Diseases ... Rare Disorders : Melorheostosis ITEMS: LINKS:
  • Electronic Journal of Hand Surgery
    A case study of a girl who had progressive and abnormal growth of the index finger of her left hand which was not enlarged at birth but grew steadily after birth. The suggested diagnosis is melorheostosis.
    (Rating: 0.00 Votes: 0) Rate It
  • Information on Melorheostosis
    Designed to share research information as well as provide a location where others who are either suffering from this condition or attempting to treat it can share information and experiences.
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  • Melorheostosis.com
    Links to research, articles, personal histories of patients and a discussion board.
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26. Vertebral Melorheostosis - General Practice Notebook
medical information from General Practice Notebook. vertebral melorheostosis.This is a common disease of the spine seen in the elderly.
http://www.gpnotebook.co.uk/cache/1114308674.htm
vertebral melorheostosis This is a common disease of the spine seen in the elderly. The most striking feature is the exuberant formation of degenerative osteophytes. Often the condition is asymptomatic but it may present with stiffness and pain.
Click here for more information...

27. Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource
Isolated cases of malignancy have been reported in association with melorheostosis,one osteosarcoma and one malignant fibrous histiocytoma.
http://bonetumor.org/tumors/pages/page157melor.htm
Meloreostosis, Leri's disease, flowing periosteal hyperostosis
This disease was described by Leri and Joanny in 1922. It is a rare, non-hereditary lesion that affects both sexes. It is usually apparent in early childhood and even in the first few days of life. About 50% of persons affected will develop the symptoms by 20 years of age. The classic radiographic appearance is that of sclerotic lesions of bones that look like wax dripping down the side of a candle. the name is derived from the greek melos "limb" and rhein "to flow". With an estimated incidence of 0.9 cases per million persons, it can be calculated that there are approximately 1,000,000 to 1,500,000 persons with meloreostosis currently alive. However, only about 300 cases have been reported in the literature. Patients with meloreostosis may have associated cutaneous and soft tissue lesions such as vascular malformations, neurofibromatosis, hemangioma, arterial aneurysms, linear scleroderma, tuberous sclerosis, hemangiomas, and focal subcutaneous fibrosis. Adults generally complain of pain, joint stiffness, and progressive deformity. In children the condition affects mainly the bones of the extremities and pelvis, and may result in limb length inequality, deformity, or joint contractures. Joint contractures may be accompanied by extraosseous bone formation.

28. Uhrad.com - Musculoskeletal Imaging Teaching Files
Case Thirteen melorheostosis of Phalanges. Diagnosis 1. melorheostosisof the distal and proximal phalanges of the hallux (biopsy proven).
http://www.uhrad.com/msiarc/msi013.htm
uhrad.com - Musculoskeletal Imaging Teaching Files
Case Thirteen - Melorheostosis of Phalanges.
Click on Images for Enlarged View Clinical History: Pain and swelling of the hallux in a 40 yo woman. Findings: There is prominent sclerosis involving the terminal tuft of the great toe, extending the entire length of the phalanx medially. Additionally, there is a linear area of sclerosis in the distal medial proximal phalanx. A small round area of sclerosis is seen in the head of the hallux metatarsal. Diagnosis: 1. Melorheostosis of the distal and proximal phalanges of the hallux (biopsy proven). 2. Enostosis (bone island) of the head of the hallux metatarsal. Discussion: Melorheostosis is an uncommon nonhereditary sclerosing bone disorder which often presents with pain and decreased range of motion, though it may often be detected incidentally. Our patient, seen at the proverbial outside hospital, underwent biopsy which was consistent with the radiographic diagnosis of melorheostosis. Association with the other sclerosing bone dysplasias (osteopoikilosis, osteopathia striata my be seen, and is known as mixed sclerosing bone dystrophy. This may in turn be associated with vascular and/or lymphatic anomalies, or Trevor's disease. Isolated melorheostosis may be associated with linear scleroderma, neurofibromatosis, or tuberous sclerosis, as well. The typical distribution is sclerotomal in one or more bones of an extremity. The axial skeleton can also be involved, however, either separately or in conjunction with extremity findings.

29. Orthoguide.com Melorheostosis
Search results for melorheostosis . NO MATCHES FOUNDPlease select a differentkeyword or category OR Search AltaVista for 'melorheostosis'.
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30. Melorheostosis: Review And Update [CARJ - October 1999]
Bone dysplasia series melorheostosis review and update. melorheostosis is a rarenongenetic developmental anomaly first described in 1922 by Léri and Joanny.
http://collection.nlc-bnc.ca/100/201/300/cdn_medical_association/carj/vol-50/iss
Bone dysplasia series
Melorheostosis: review and update Adam Greenspan, MD, FACR; E. Michel Azouz, MD, FRCPC Can Assoc Radiol J 1999;50:324-330 Abstract melos ) and flow ( rhein melos (membre) et rhein Send a letter to the editor
Addresss for correspondence: Key words: sclerosing bone dysplasia, melorheostosis, developmental anomalies, bone sclerosis Submitted Feb. 22, 1999
Revision requested Mar. 30, 1999
Resubmitted May 19, 1999
Accepted May 26, 1999

31. ECR '99 - Presentation 1299
1299. J. Freyschmidt Bremen/D. melorheostosis staging of 23 cases.Purpose To reevaluate the radiographic spectrum of melorheostosis.
http://www.ecr.org/T/ECR99/sciprg/abs/p001299.htm
J. Freyschmidt
Bremen/D Melorheostosis - staging of 23 cases Purpose: To reevaluate the radiographic spectrum of melorheostosis. Methods and Materials: We investigated 23 cases of melorheostosis in our files. Evaluated were: radiographic appearance; involved skeletal region (i.e. upper/lower limbs); number of involved bones. Results: Five basic forms of radiographic patterns were found: 1. The osteoma like pattern (7 cases). 2. The classic pattern with "flowing candle wax" appearance (5 cases). 3. The extraosseous myositis ossificans like pattern (1 case). 4. The osteopathia striata like pattern (6 cases). 5. Mixed pattern (3 cases with type four and three pattern, 1 case with type one and three pattern). In 5 cases the upper limbs including the shoulder girdle were involved, in 16 cases the lower limbs including the pelvis, in 1 case the upper and lower limbs, and in 1 case the sacrum. In 10 cases only 1 bone was affected, in 4 cases 2 bones and in 9 cases 3 or more bony elements. Conclusion: The radiographic spectrum of melorheostosis is broader than reported in the literature up to now. We classified 5 basic forms of radiographic appearance, that open a corresponding spectrum of differential diagnosis (i.e. parosseal osteosarcomas). As the histology of melorheostosis is unspecific, a correct clinical-radiological diagnosis is important. Possible pathogenesis and associated clinical abnormalities of melorheostosis will be discussed.

32. ECR '99 - Presentation 1299
1299. melorheostosis staging of 23 cases. J. Freyschmidt Bremen/D.Purpose To reevaluate the radiographic spectrum of melorheostosis.
http://www.ecr.org/Conferences/ECR1999/sciprg/abs/p001299.htm
Melorheostosis - staging of 23 cases J. Freyschmidt
Bremen/D Purpose: To reevaluate the radiographic spectrum of melorheostosis. Methods and Materials: We investigated 23 cases of melorheostosis in our files. Evaluated were: radiographic appearance; involved skeletal region (i.e. upper/lower limbs); number of involved bones. Results: Five basic forms of radiographic patterns were found: 1. The osteoma like pattern (7 cases). 2. The classic pattern with "flowing candle wax" appearance (5 cases). 3. The extraosseous myositis ossificans like pattern (1 case). 4. The osteopathia striata like pattern (6 cases). 5. Mixed pattern (3 cases with type four and three pattern, 1 case with type one and three pattern). In 5 cases the upper limbs including the shoulder girdle were involved, in 16 cases the lower limbs including the pelvis, in 1 case the upper and lower limbs, and in 1 case the sacrum. In 10 cases only 1 bone was affected, in 4 cases 2 bones and in 9 cases 3 or more bony elements. Conclusion: The radiographic spectrum of melorheostosis is broader than reported in the literature up to now. We classified 5 basic forms of radiographic appearance, that open a corresponding spectrum of differential diagnosis (i.e. parosseal osteosarcomas). As the histology of melorheostosis is unspecific, a correct clinical-radiological diagnosis is important. Possible pathogenesis and associated clinical abnormalities of melorheostosis will be discussed.

33. Directory :: Look.com
melorheostosis (3) See Also. Health/Conditions and Diseases/MusculoskeletalDisorders. Sites. The suggested diagnosis is melorheostosis.
http://www.look.com/searchroute/directorysearch.asp?p=523641

34. Untitled
melorheostosis. HOME. The etiology of melorheostosis is thus far unknown. Therehave been certain theories proposed but to this point have not been proven.
http://www.med.mun.ca/ortho/pages/melorostosis.htm
Melorheostosis HOME Melorheostosis is a rare, non-familial condition of hyperostosis of the cortical bone that usually presents unilaterally in long bones but has also presented in vertebra, ribs, skull and jaw. It usually involves the periostium and endostium of diaphyseal cortical bone and can be associated with various soft tissue changes. The incidence of this condition is quite rare, approximately only 400 known cases reported worldwide. However, the prevalence in the population that remains undetected is significantly higher and estimates on the order of 1–1.5 million worldwide have been suggested. The age of presentation ranges from the neonatal period to the elderly. The peak age of presentation is between the ages of 5 and 20 and approximately half of the cases are detected by age 20. There are no gender differences in the reported cases as well as no difference with respect to ethnicity suggesting increase risk in certain populations. The etiology of melorheostosis is thus far unknown. There have been certain theories proposed but to this point have not been proven. One theory is that an embryonic infection of a sensory nerve is responsible for the pathogenesis. This was proposed on the basis of cases where multiple lesions found in the same limb, tend to be associated with a single sclerotome. Another theory that has been proposed is that of a mosaicism. This would better explain the sporadic and asymmetric pattern found in some cases.

35. Melorheostosis Website Results :: Linkspider UK
melorheostosis Websites from the Linkspider UK. melorheostosis Directory.Complete Results for melorheostosis Related Topics. melorheostosis
http://www.linkspider.co.uk/Health/ConditionsandDiseases/RareDisorders/Melorheos
Melorheostosis Websites from Linkspider UK Keyword: Melorheostosis Linkspider UK Directory
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36. Irish Medical Journal
D. Sir – melorheostosis is an uncommon bone disorder characterisedby cortical thickening with irregular dense hyperostosis. It
http://www.imj.ie/news_detail.php?nNewsId=2585&nVolId=99

37. Listings Of The World Health Conditions And Diseases Rare
enlarged at birth but grew steadily after birth. The suggested diagnosisis melorheostosis. http//www.leeds.ac.uk/handsurgery/EJHS
http://listingsworld.com/Health/Conditions_and_Diseases/Rare_Disorders/Melorheos

38. Hand Cases To Consider - Answer To Case 1
Case 1. Case 1. Diagnosis melorheostosis. melorheostosis was first describedby Leri and Joanny in 1922. The etiology of melorheostosis is unknown.
http://www.orthop.washington.edu/medprof/cme/handcases/02

39. Olgu Sunumu / Case Report
Olgu Sunumu / Case Report. melorheostosis Review of The Literature Basedon a New Case. Keywords Bone dysplasia, sclerosis, melorheostosis.
http://www.ftr.org.tr/Dergi/ocak2002/9Ecekapt.htm
Olgu Sunumu / Case Report
MELORHEOSTOSIS: Review of The Literature Based on a New Case Ece KAPTANOÐLU*, V. NACÝTARHAN*, T. ERCELCAN**, S. DÖKMETAÞ*** ABSTRACT: Melorheostosis is an uncommon bone dysplasia of unknown origin, characterized by a slowly progressing hyperostosis. It was first reported by Leri and Joanny in 1922, and approximately 300 cases have been reported in the literature. In the present article we described an unusual case of melorheostosis of both hands with associating generalized osteopenia. A discussion of the case and a brief review of the literature on the subject were presented. Keywords: Bone dysplasia, sclerosis, melorheostosis. ÖZET: MELORHEOSTOSIS: Bir olgu sunumu ve literatürün gözden geçirilmesi Melorheostosis yavaþ ilerleyen hiperostozisle karakterize, sebebi tam olarak bilinmeyen ve nadir görülen bir kemik displazisidir. Ýlk kez Leri and Joanny tarafýndan 1922’de tanýmlanmýþtýr ve günümüze kadar yaklaþýk 300 vaka bildirilmiþtir. Bu makalede, jeneralize osteopeninin eþlik ettiði, bilateral el tutulumlu bir melorheostosis olgusu sunulmuþ ve literatür gözden geçirilmiþtir. Anahtar Kelimeler: Kemik displazisi, skleroz, melorheostosis.

40. Melorheostosis
Health. SUBCATEGORIES. Up. melorheostosis Electronic Journal The suggesteddiagnosis is melorheostosis. Information on melorheostosis
http://www.medlina.com/melorheostosis.htm
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Melorheostosis Electronic Journal of Hand Surgery - http://www.leeds.ac.uk
A case study of a girl who had progressive and abnormal growth of the index finger of her left hand which was not enlarged at birth but grew steadily after birth. The suggested diagnosis is melorheostosis. Information on Melorheostosis - http://www.melorheostosis.com
Designed to share research information as well as provide a location where others who are either suffering from this condition or attempting to treat it can share information and experiences. Melorheostosis.com - http://206.139.180.51 Links to research, articles, personal histories of patients and a discussion board. SUBCATEGORIES Up powered by A merica M edica

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