81. Musculoskeletal Lab 1f Musculoskeletal and Skin Pathology for Medical II Students. Lab 1f MicroscopicPolyangiitis/Polyarteritis (5600047720). The nomenclature http://www.pathology.vcu.edu/education/musculo/lab1.f.html

V i r g ... Molecular Diagnostics Pra cticum Musculoskeletal and Skin Pathology for Medical II Students Lab 1f Microscopic Polyangiitis/Polyarteritis (56000-47720) The nomenclature for systemic vasculitides has been a problem since 1866, when an autopsy of a 27 year old male provided the material for the first classic description. An attempt has been made to standardize the criteria for diagnosis Microscopic polyangiitis - Necrotizing vasculitis with few or no immune deposits affecting small blood vessels (i.e. arterioles, capillaries or venules). - Necrotizing glomerulonephritis very common - Inflammation of pulmonary capillaries often occurs - Strong association with p eri-nuclear pattern A nti -N eutrophil C ytoplasmic A ntibodies (p-ANCA) - May be associated with necrotizing inflammation of small and medium-sized arteries. Polyarteritis Nodosa - Arteritis of medium sized and small arteries - No involvement of smaller vessels (i.e. arterioles, capillaries or venules, including glomerular capillaries). - A rare form of vasculitis.

82. Intenal Medicine Contents Vol.40 No.6 HIDA W. Antineutrophil Cytoplasmic Antibody Associated MicroscopicPolyangiitis and Sinobronchial Syndrome YOSHIDA M. Antineutrophil http://www.naika.or.jp/im/im40/im40-6.html

Multiple Endocrine Neoplasia Type 1: Usefulness of Genetic Tests in Atypical Cases SATO M, MATSUBARA S, MURAO K, ISHIDA T and TAKAHARA J Novel Aspects of Primary Alveolar Hypoventilation HIDA W Antineutrophil Cytoplasmic Antibody Associated Microscopic Polyangiitis and Sinobronchial Syndrome YOSHIDA M Anti-neutrophil Cytoplasmic Antibodies Tests: Which Tests Should be Used in Practice? Transesophageal Echocardiography for Detection of Cardiac Diseases in Patients with Retinal Artery Occlusion Idiopathic Hemochromatosis with the Mutation of Ala176Val Heterozygous for HFE Gene Hepatic Necrosis with Cholestasis Induced by Long-term Voglibose Administration A Patient with Chronic Hepatitis C Who Obtained Sustained Response by Retreatment of Interferon after Decrease of Viral Load and Mutation in Interferon Sensitivity Determining Region Inflammatory Pseudotumor of the Liver Complicated with Recurrent Gouty Arthritis A Germline Mutation, 1001delC, of the Multiple Endocrine Neoplasia Type 1 (MEN 1) Gene in a Japanese Family Marked Uptake of Technetium-99m Pertechnetate by Parathyroid Adenoma Three Patients with Isolated Adrenocorticotropin Deficiency Presenting with Neuroleptic Malignant Syndrome-like Symptoms Simultaneous Onset of Type 1 Diabetes Mellitus and Painless Thyroiditis Following Acute Pancreatitis Transient Renal Glycosuria in a Patient with Acute Pyelonephritis The Spectrum of CFTR-related Disease Familial Adult Onset Primary Alveolar Hypoventilation Syndrome

83. Postgraduate Medicine: Symposium: Rheumatologic Diseases Small to medium vessels Wegener's granulomatosis ChurgStrauss syndrome Microscopicpolyangiitis. Medium vessels Polyarteritis nodosa Kawasaki syndrome. http://www.postgradmed.com/issues/1998/02_98/bush.htm

Systemic vasculitis Diagnostic clues to this confusing array of diseases Thomas M. Bush, MD VOL 103 / NO 2 / FEBRUARY 1998 / POSTGRADUATE MEDICINE This page is best viewed with a browser that supports tables This is the first of five articles on rheumatologic diseases Preview : Systemic vasculitis can be difficult to recognize because of the many types of the disease and the conditions that can mimic it. However, early identification and initiation of treatment (often empirical) are important to avoid severe morbidity. In this symposium article, Dr Bush clearly describes the most common types of vasculitis according to current nomenclature based on the size of affected vessels. Illustrations of common signs of the various types of vasculitis are also included. S ystemic vasculitides are characterized by aberrant immune responses that result in inflammation and necrosis of blood vessels. The immune dysfunction may be triggered by infection, autoimmune disease, or exposure to a drug; often the cause is unknown. The categorization of vasculitis by the size of the involved blood vessels is a useful guide to diagnosis and therapy(1-3) (table 1). The most recent nomenclature for vasculitis was developed by a multispecialty panel at the Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitis (3). This article presents a review of the chief types of vasculitis with an emphasis on important diagnostic features. Table 1. Classification of systemic vasculitis

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