1. NINDS Mobius Syndrome Information Page Also known as congenital facial diplegia, an information sheet compiled by NINDS.Category Health Conditions and Diseases mobius syndrome......mobius syndrome (Congenital Facial Diplegia) information sheet compiled bythe National Institute of Neurological Disorders and Stroke (NINDS). http://www.ninds.nih.gov/health_and_medical/disorders/mobius.htm

National Institute of Neurological Disorders and Stroke Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Browse all disorders Browse all health organizations More about Mobius Syndrome Studies with patients Research literature Press releases Search NINDS... (help) Contact us My privacy NINDS is part of the National Institutes of Health NINDS Mobius Syndrome Information Page Synonym(s): Congenital Facial Diplegia Reviewed 07-01-2001 Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Mobius Syndrome? Is there any treatment? What is the prognosis? What research is being done? ... Organizations What is Mobius Syndrome? Is there any treatment? There is no specific course of treatment for Mobius syndrome. Treatment is supportive and symptomatic. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct strabismus and improve limb and jaw deformities. Physical and speech therapy may improve motor skills and coordination, and help to better control speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Also, in a few cases, nerve and muscle transfers (microvascular muscle transplant) to the corners of the mouth have been performed to provide some ability to smile. What is the prognosis?

2. Mobius Syndrome Details about this disease, including what it is, the causes, symptoms and treatment options. http://healthlink.mcw.edu/article/921441372.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Mobius Syndrome Mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These nerves control eye movements and facial expression. In newborns, the first symptom is an inability to suck. Excessive drooling and strabismus (crossed eyes) may occur. Other symptoms may include lack of facial expression; inability to smile; feeding, swallowing, and choking problems; eye sensitivity; motor delays; high or cleft palate; hearing problems; and speech difficulties. Deformities of the tongue, jaw, and limbs, such as club foot and missing or webbed fingers, may also occur. Most patients have low muscle tone, especially in the upper body. Mental retardation may also occur. As children get older, lack of facial expression and inability to smile become the dominant visible symptoms. Mobius syndrome may be accompanied by Pierre Robin syndrome, a disease in which there is an abnormally small jaw, downward displacement of the tongue, and a soft, cleft palate. It may also be accompanied by Poland's anomaly, a disease characterized by abnormal development of one side of the chest and limb deformities.

3. HONselect - Mobius Syndrome Translate this page English mobius syndrome, - Congenital Oculofacial Paralysis, Moebius - Moebius CongenitalOculofacial Paralysis - Moebius Syndrome - mobius syndromes - Moebius http://www.hon.ch/HONselect/RareDiseases/C10.292.300.825.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Mobius Syndrome - Congenital Oculofacial Paralysis, Moebius - Moebius Congenital Oculofacial Paralysis - Moebius Syndrome - Mobius Syndromes - Moebius Syndromes - Syndrome, Mobius Français: MOBIUS, SYNDROME Deutsch: Moebius-Syndrom - Gesichtslähmung Español: SINDROME DE MOBIUS Português: SINDROME DE MOBIUS HONselect ressources Definition: Yes Articles: Yes Images: No News: No Conferences: No Clinical trials: No Web sites: English Yes Français No Deutsch No Español No Português No Home About us Site map Feedback ... HONewsletter http://www.hon.ch/HONselect/RareDiseases/C10.292.300.825.html Last modified: Thu Jul 25 2002

4. Mobius Syndrome mobius syndrome. mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or http://oci.mcw.edu/article/921441372.html

Search: search tips Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Mobius Syndrome Mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These nerves control eye movements and facial expression. In newborns, the first symptom is an inability to suck. Excessive drooling and strabismus (crossed eyes) may occur. Other symptoms may include lack of facial expression; inability to smile; feeding, swallowing, and choking problems; eye sensitivity; motor delays; high or cleft palate; hearing problems; and speech difficulties. Deformities of the tongue, jaw, and limbs, such as club foot and missing or webbed fingers, may also occur. Most patients have low muscle tone, especially in the upper body. Mental retardation may also occur. As children get older, lack of facial expression and inability to smile become the dominant visible symptoms. Mobius syndrome may be accompanied by Pierre Robin syndrome, a disease in which there is an abnormally small jaw, downward displacement of the tongue, and a soft, cleft palate. It may also be accompanied by Poland's anomaly, a disease characterized by abnormal development of one side of the chest and limb deformities.

5. NINDS - News And Events Paresthetica Metachromatic Leukodystrophy Microcephaly Miller Fisher Syndrome MiniStrokesMitochondrial Myopathies mobius syndrome Monomelic Amyotrophy Motor http://www.ninds.nih.gov/health_and_medical/news.htm

National Institute of Neurological Disorders and Stroke Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Browse all disorders Browse all health organizations More about a disorder Studies with patients Research literature Press releases Search NINDS... (help) Contact us My privacy NINDS is part of the National Institutes of Health Please Select a Disorder (includes synonyms and research topics) Select a letter to jump to the disorder... or return to top of page A B C D ... Z A ADHD AIDS - Neurological Manifestations Acquired Epileptiform Aphasia Acute Disseminated Encephalomyelitis ... Autonomic Dysfunction Select a letter to jump to the disorder... or return to top of page A B C D ... Z B Back Pain Barth Syndrome Batten Disease Behcet's Disease ... Bulbospinal Muscular Atrophy Select a letter to jump to the disorder... or return to top of page A B C D ... Z C Canavan Disease Carpal Tunnel Syndrome Causalgia Cavernomas ... Cytomegalovirus Infection Select a letter to jump to the disorder... or return to top of page A B C D ... Z D Dancing Eyes-Dancing Feet Syndrome Dandy-Walker Syndrome Dawson Disease De Morsier's Syndrome ... Dystonias Select a letter to jump to the disorder... or return to

6. MOBIUS SYNDROME mobius syndrome is a rare congenital disturbance consisting of varying involvement of facial and lateral gaze paresis. http://members.aol.com/scottolitsky/mobius.htm

MOBIUS SYNDROME Mobius syndrome is a rare congenital disturbance consisting of varying involvement of facial and lateral gaze paresis. Mobius first suggested that congenital bilateral abducens-facial paralysis might be an independent pathologic entity, thus gaining eponymic distinction. Clinical Manifestations Mobius syndrome is characterized by unilateral or bilateral inability to abduct the eyes. Although horizontal movements are usually lacking, vertical movements and convergence are intact. Pupillary constriction, vision, and the retina are generally normal. Congenital esotropia is common in children with Mobius syndrome. In a retrospective study of 61 patients with this syndrome, 38 per cent had early-onset esotropia. The unilateral or bilateral complete or incomplete facial palsy is usually observed during the first few weeks of life because of difficulty with sucking and feeding, and incomplete closure of the eyelids during sleep. These patients typically have masklike faces with an inability to grin and wrinkle the forehead. Mobius syndrome is frequently associated with paresis of other muscles supplies by the cranial nerves. Often, there is partial atrophy of the tongue with inability to protrude the tongue beyond the lips. Paralysis of the soft palate and muscles of mastication may also occur. Various skeletal and muscle defects are common, including absence or hypoplasia of the pectoral muscles, syndactyly, club feet, and congenital limb amputations.

7. Biology - Past Issues Of Weekly Features Symptoms, diagnosis, and treatment of mobius syndrome. Information on research, community outreach and support. http://genetics.about.com/science/genetics/library/blmob.htm

zfp=-1 About Homework Help Biology Search in this topic on About on the Web in Products Web Hosting Biology with Regina Bailey Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects ESSENTIALS Science Fair Projects Top Biology Programs Biology How Tos ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Most Recent Features... Biological Weapons Biological weapons are toxic materials derived from pathogenic organisms for the purpose of killing or incapacitating a host. Land Biomes: Deserts Deserts are dry areas that experience extremely small amounts of rainfall. They can be either cold or hot. Predator or Prey Game The predator-prey relationship is important in maintaining balance between different animal species. In this game you must choose the correct predator-prey relationship. My First Book About DNA My First Book About DNA is a wonderful resource for parents and teachers seeking to help young students become familiar with DNA, genes, and cells. Land Biomes: Savannas Savannas are areas of open grasslands with very few trees.

8. Healthlink Template Disease; Megalencephaly; Menkes Disease; Metachromatic Leukodystrophy;Microcephaly; mobius syndrome; MultiInfarct Dementia; Muscular http://healthlink.mcw.edu/search/search-page.php?neurology

9. Rd.com: A list of alternate names for mobius syndrome, along with a general discussion and resources. http://www.rd.com/common/nav/index.jhtml?articleId=8612437

10. Mobius Syndrome mobius syndrome. This article submitted by Shawn K. Centers, DO on4/14/95. mobius syndrome is a conginital disorder involving (1 http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/MobiusSynd

Mobius Syndrome This article submitted by Shawn K. Centers, DO on 4/14/95. Mobius syndrome is a conginital disorder involving (1)complete or partial VIIth nerve palsy (2)abducens palsy (3) limb malformations especially talipes (3) less commonly there may be palsies of the Vth, IXth, and XXIIth CN's. There have been less than 80 reported cases in the literature. I am interested in the pathogenesis of this disorder and any additional known cases. Next Article Previous Article Return to Topic Menu Here is a list of responses that have been posted to this article... Rea Respiratory Palsy (1/14/97) 8:35 PM Nerve Transplant IN Moebius (12/21/96) 2:30 PM Nerve Transplanted (12/21/96) 12:31 PM Leslie (12/19/96) 2:16 PM ... Mobius Syndrome (5/16/95) 2:10 PM You now have TWO OPTIONS: Post a new Article or post a Response to this Article Click here to post a new Article! If you would like to post a Response to this article, fill out this form completely... Do not use slashes ("/") or colons (":") in your Article title! Response Title: Author: Response Text: Original Article: (Don't change this field!)

11. Mobius Syndrome mobius syndrome. As I understand it, current thinking suggests thatmobius syndrome may result from a vascular field defect (ie. http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/MobiusSynd

Mobius Syndrome This response submitted by Barry Kosofsky- MGH Child Neuro on 5/16/95. Dr. Centers, Sorry for the delay, but we are just coming on-line. As I understand it, current thinking suggests that Mobius Syndrome may result from a vascular field defect (ie. failure of perfusion of a specific vessel during fetal life, with maldevelopment of the neural, muscular, and other tissue structures normally perfused by that vessel). There was an article that you should be able to pull from a literature search of "Mobius Syndrome" that was published (? in Peds or J Peds, or Teratology) about 2 years ago that dicusses this theory (and other field defects such as POLAND Syndrome). Good Luck, Barry E. Kosofsky, M.D., Ph.D. Next Article Return to Main Article Article complete. Click HERE to return to the Neurology Web-Forum Menu.

12. NINDS Mobius Syndrome Information Page mobius syndrome (Congenital Facial Diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). What is mobius syndrome? mobius syndrome, a rare genetic disorder characterized by facial paralysis, is caused by the http://accessible.ninds.nih.gov/health_and_medical/disorders/mobius.htm

Disorders - National Institute of Neurological Disorders and Stroke (NINDS) Skip menus Main sections of the NINDS web site Home About NINDS Disorders-you are in this section ... Find People Disorders section pages and search Image Description Science For the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system. Select Topic Disorder Quick Links Alzheimer's Autism Cerebral Palsy Chronic Pain Epilepsy Headache Multiple Sclerosis Parkinson's Stroke Traumatic Brain Injury More about NINDS Mobius Syndrome Information Page Studies with patients Research literature Press release NINDS Search (search help) Contact us My privacy NINDS is part of the National Institutes of Health Contact us Content for this page NINDS Mobius Syndrome Information Page Synonym(s): Congenital Facial Diplegia Reviewed 07-01-2001 Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Mobius Syndrome? Is there any treatment? What is the prognosis? What research is being done? ... Organizations What is Mobius Syndrome? Is there any treatment?

13. MOBIUS SYNDROME mobius syndrome. mobius syndrome is a rare congenital disturbance consistingof varying involvement of facial and lateral gaze paresis. http://www.members.aol.com/scottolitsky/mobius.htm

MOBIUS SYNDROME Mobius syndrome is a rare congenital disturbance consisting of varying involvement of facial and lateral gaze paresis. Mobius first suggested that congenital bilateral abducens-facial paralysis might be an independent pathologic entity, thus gaining eponymic distinction. Clinical Manifestations Mobius syndrome is characterized by unilateral or bilateral inability to abduct the eyes. Although horizontal movements are usually lacking, vertical movements and convergence are intact. Pupillary constriction, vision, and the retina are generally normal. Congenital esotropia is common in children with Mobius syndrome. In a retrospective study of 61 patients with this syndrome, 38 per cent had early-onset esotropia. The unilateral or bilateral complete or incomplete facial palsy is usually observed during the first few weeks of life because of difficulty with sucking and feeding, and incomplete closure of the eyelids during sleep. These patients typically have masklike faces with an inability to grin and wrinkle the forehead. Mobius syndrome is frequently associated with paresis of other muscles supplies by the cranial nerves. Often, there is partial atrophy of the tongue with inability to protrude the tongue beyond the lips. Paralysis of the soft palate and muscles of mastication may also occur. Various skeletal and muscle defects are common, including absence or hypoplasia of the pectoral muscles, syndactyly, club feet, and congenital limb amputations.

14. Google Directory - Health > Conditions And Diseases > Genetic Disorders > Mobius Moebius Syndrome Foundation http//www.ciaccess.com/moebius/ Bringing together information from and links to medical and lay support for those affected by Moebius syndrome. mobius syndrome - http// www. Search only in mobius syndrome Search the Web. mobius syndrome http://directory.google.ch/Top/Health/Conditions_and_Diseases/Genetic_Disorders/

Directory Help Search only in Mobius Syndrome Search the Web Mobius Syndrome Health Conditions and Diseases Genetic Disorders Go to Directory Home Web Pages Viewing in Google PageRank order View in alphabetical order Moebius Syndrome Foundation http://www.ciaccess.com/moebius/ Bringing together information from and links to medical and lay support for those affected by Moebius syndrome. Mobius Syndrome http://www.ninds.nih.gov/health_and_medical/disorders/mobius.htm Also known as congenital facial diplegia, an information sheet compiled by NINDS. MCW Healthlink: Mobius Syndrome http://healthlink.mcw.edu/article/921441372.html Details about this disease, including what it is, the causes, symptoms and treatment options. About.com with Laura L. Jelliffe, Ph.D. http://genetics.about.com/science/genetics/library/blmob.htm Symptoms, diagnosis, and treatment of mobius syndrome. Information on research, community outreach and support. Readers Digest Health http://www.rd.com/common/nav/index.jhtml?articleId=8612437 A list of alternate names for mobius syndrome, along with a general discussion and resources.

15. Untitled Sixth Nerve Palsy(Abducens Nerve Palsy). Double Elevator Palsy. Duane's RetractionSyndrome. Brown's Syndrome. mobius syndrome. Congenital Fibrosis Syndrome. http://www.members.aol.com/scottolitsky/webbook.htm

Strabismus Web Book Authors Scott E. Olitsky, M.D. The Children's Mercy Hospital, Kansas City Leonard B. Nelson, M.D. Wills Eye Hospital, Philadelphia Chapters Pseudoesotropia Congenital Esotropia Accommodative Esotropia Intermittent Exotropia ... Third Nerve Palsy (Oculomotor Nerve Palsy) Fourth Nerve Palsy (Superior Oblique Palsy) Sixth Nerve Palsy (Abducens Nerve Palsy) Double Elevator Palsy Duane's Retraction Syndrome Brown's Syndrome Mobius Syndrome ... Congenital Fibrosis Syndrome

16. 1Up Health > Mobius Syndrome [Congenital Facial Diplegia] - Birth Defects & Gene Variants of mobius syndrome and Central Neurologic Impairment Lindeman Procedure in Children. http://www.1uphealth.com/medical/disease/birth-defects-genetic-disease/mobius-sy

Home Contact Us Privacy Caring For Your Well Being Alternative Medicine Clinical Trials Health News Poisons ... Health Topics A-Z Search 1Up Health 1Up Health Mobius Syndrome [Congenital Facial Diplegia] Diseases and Conditions A B C D ... Z Mobius Syndrome [Congenital Facial Diplegia] Selected references Miller, M, et. al. Mobius and Mobius-like Syndrome. Journal of Pediatric Ophthalmology and Strabismus, 26:4; 176-188 (July-August 1989). Raroque, H, et. al. Mobius Syndrome and Transposition of the Great Vessels. Neurology, 38; 1894-1895 (1988). Cohen, S, and Thompson, J. Variants of Mobius Syndrome and Central Neurologic Impairment: Lindeman Procedure in Children. Annals of Otology, Rhinology, and Laryngology, 96; 93-100 (1987). Previous Next What is Mobius Syndrome? Is there any treatment? ... Mobius Syndrome [Congenital Facial Diplegia] Acknowledgement National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health (NIH) Related Main Page Health Articles Diseases-Conditions Surgery-Procedure Medical Tests More.....

17. HON - List Of Rare Diseases Mikulicz' Disease, Miller Fisher Syndrome. mobius syndrome, MoyamoyaDisease. Mucocutaneous Lymph Node Syndrome, Mucopolysaccharidosis I. http://www.hon.ch/HONselect/RareDiseases/

List of rare diseases: English Deutsch Acrocephalosyndactylia Acrodermatitis ... HONewsletter http://www.hon.ch/HONselect/RareDiseases/index.html Last modified: Thu Sep 26 2002

18. Mobius Syndrome mobius syndrome. Synonym(s) Congenital Facial Diplegia What is mobius syndrome? Thereis no specific course of treatment for mobius syndrome. http://www.clevelandclinic.org/health/health-info/docs/1300/1307.asp?index=6064

19. Show-documents.asp mobius syndrome Written Information. Care Treatment., mobius syndrome. New Search. Health Extra Menu. http://www.clevelandclinic.org/healthextra/do-query.asp?TopicId=1329

20. Mobius, Syndrome : Sites Et Documents Francophones Translate this page Voir aussi paralysie faciale . Arborescence(s) du thesaurus MeSHcontenant le mot-clé Mobius, syndrome mobius syndrome http://www.chu-rouen.fr/ssf/pathol/mobiussyndrome.html

Mobius, Syndrome Menu général CISMeF Voir aussi paralysie faciale Arborescence(s) Mobius, syndrome Mobius syndrome maladies et malformations congénitales, héréditaires et néonatales système nerveux, maladies Position du mot-clé dans l' (les) arborescence(s) : Vous pouvez consulter toutes les ressources ou seulement les principales ou utiliser l' outil de recherche les recommandations les documents concernant l' enseignement les documents destinés aux patients 20 janvier 2003 courriel Menu général CISMeF Haut de page © CHU de Rouen . Toute utilisation partielle ou totale de ce document doit mentionner la source.

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