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         Multiple Hamartoma Syndrome:     more detail

41. M Website Results :: Linkspider UK
Sensitivity@ (26); multiple hamartoma syndrome@ (3); Multiple Myeloma@(17); Multiple Personality Disorder@ (107); Multiple Sclerosis
http://www.linkspider.co.uk/Health/ConditionsandDiseases/M/
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  • Myotonic Dystrophy
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    4); MRKH@ (13); Mucopolysaccharidosis 3@ (4); Multiple Chemical Sensitivity@(26); multiple hamartoma syndrome@ (3); Multiple Myeloma
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  • 43. The Indian Journal Of Radiology And Imaging - Archives:19990901 - Radiological Q
    leontiasis ossea. Coexisting conditions in LDD include Cowden's disease,which is also called multiple hamartoma syndrome. It is
    http://www.ijri.org/archives/19990901/radquiz01.htm
    Radiological Quiz - Neuroradiology SUREKHA K, AK GUPTA, SANTHOSH JOSEPH, KESAVADAS C, NKK PRABHU Ind J Radiol Imag 1999; 9:1: 25-27 A fifty-seven-years old man was well until one year prior to admission to the hospital. He developed recurrent attacks of headache and vomiting with increased frequency of symptoms about one month prior to admission. He also complained of swaying to either side. Examination revealed bilateral papilledema. In addition he also had multiple subcutaneous lipomas and papules over the body. CT and MR were performed (Figs. 1, 2). Fig 1 A
    Fig 1 B
    Fig.1 (A,B): T1W axial MR (A) and T2 W coronal MR (B) of the brain
    Fig. 2 : CT of the brain
    RADIOLOGICAL DIAGNOSIS: Lhermitte-Duclos Disease (LDD) CT shows an ill-defined hypodense lesion of the right cerebellum with significant mass effect (Fig. 1). MR reveals a hypointense mass on the T1W images (Fig. 2A) and a laminated, striated or folial pattern of increased signal on the T2W images (Fig. 2B). The patient underwent decompression and partial resection of the lesion. On surgery, the cerebellum showed thickened folia. Pathological features demonstrated were suggestive of Lhermitte-Duclos disease (LDD). Dermatological consultation with biopsy of skin lesions was consistent with Cowden's disease.

    44. Guidelines Of Care For Nevi. II. Nonmelanocytic Nevi, Hamartomas, Neoplasms, And
    Allen BS, Fitch MH, Smith JG Jr. multiple hamartoma syndrome. J AM ACADDERMATOL 1980;23038. Amaral AL, Nascimento AG, Goellner JR.
    http://www.aadassociation.org/Guidelines/nevi.html
    Guidelines of Care for Nevi. II. Nonmelanocytic Nevi, Hamartomas, Neoplasms, and Potentially Malignant Lesions This report reflects the best data available at the time the report was prepared, but caution should be exercised in interpreting the data; the results of future studies may require alteration of the conclusions or recommendations set forth in this report. Reprint requests: American Academy of Dermatology, P.O. Box 4014,
    Schaumburg, IL 60168-4014.
    J AM ACAD DERMATOL 1995;32:104-8
    Guidelines of care for nevi. II. Nonmelanocytic nevi, hamartomas, neoplasms, and potentially malignant lesions Committee on Guidelines of Care : Lynn A. Drake, MD, Chairman, Roger I. Ceilley, MD, Raymond L. Cornelison, MD, William L. Dobes, MD, William Dorner, MD, Robert W. Goltz, MD, Gloria F. Graham, MD, Charles W. Lewis, MD, David M. Pariser, MD, Stuart J. Salasche, MD, John W.. Skouge, MD, Maria L. Chanco Turner, MD, and Barbara J. Lowery, MPH Task Force on Nevi, Part II: Robert W. Goltz, MD, Chairman, David R. Barron, MD, Alvin H. Clair, MD, Kenneth G. Gross, MD, and Charles W. Lewis, MD I. Introduction

    45. Vindex, De Vindplaats Van Het Nederlandse Web
    Disorders@ Morvan Disease@, Mouth Cancer@ Moyamoya Disease@ Mucopolysaccharidosis3@ Multiple Chemical Sensitivity@ multiple hamartoma syndrome@ Multiple Myeloma
    http://www.vindex.nl/dir/Health/Conditions_and_Diseases/M

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    46. M Information Sites
    Cancer@; Moyamoya Disease@; Mucopolysaccharidosis 3@; Multiple ChemicalSensitivity@; multiple hamartoma syndrome@; Multiple Myeloma@; Multiple
    http://www.healthorgs.com/ConditionsandDiseases/M/
    HEALTHorgs.com Search The Largest Human Reviewed Health Database on Internet
    (Not sure of spelling? Use first letters and * such as abc* or abcd* or abcde*) Match:.. All Any
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    Search Words: Top Health Conditions and Diseases : M

    47. Alphabetical Topic Index (AZ) Jump To A B C D E F G H I J K L M
    Hallucinations Hallux Limitus Hallux Limitus Hallux Rigidus Hallux Rigidus HalluxValgus Hallux Valgus Hamartoma Syndrome, multiple hamartoma syndrome
    http://www.uscuh.com/apps/Intermap/topiclist/SectionH.html
    Alphabetical Topic Index (A-Z):
    Jump To: A B C D ... Hy
    H
    Ha
    Haemonchiasis

    Haemonchiasis

    Hair Loss
    Hair Loss in Men And Women

    Hairy Tongue
    Tongue, Hairy

    Halitosis
    Halitosis

    Hallermann's Syndrome Hallermann's Syndrome Hallervorden-Spatz Syndrome Hallervorden-Spatz Syndrome Hallucinations Hallucinations Hallux Limitus Hallux Limitus Hallux Rigidus Hallux Rigidus Hallux Valgus Hallux Valgus Hamartoma Syndrome, Multiple Hamartoma Syndrome, Multiple Hand Deformities, Acquired Hand Deformities, Acquired Hand Deformities, Congenital Hand Deformities, Congenital Hand Dermatoses Hand Dermatoses Hand, Foot and Mouth Disease Hand, Foot and Mouth Disease Hantavirus Infection Hantavirus Pulmonary Syndrome Hartnup Disease Hartnup Disease Hay Fever Hay Fever Back To Top ^ He Head and Neck Cancer Hypopharyngeal Cancer Salivary Gland Cancer Parathyroid Cancer Paranasal Sinus And Nasal Cavity Cancer ... Oral Cavity Cancer Head Injuries, Closed Head Injuries, Closed Head Injuries, Penetrating Head Injuries, Penetrating Headache Headache Headache: Tension Tension Headaches Headaches: Cluster Cluster Headaches Hearing Loss, Age-Associated)

    48. Diseases Database Disease, Symptom, Sign, Etc Alphabetical Index : L Diseases Da
    plasma or serum) Lhermitte's sign Lhermitte's syndrome see Internuclear ophthalmoplegiaLhermitteDuclos disease see multiple hamartoma syndrome LHRH see
    http://www.diseasesdatabase.com/sieve/disease_index_l.asp
    Diseases Database [Previous page] [Search] [Index] [Feedback]
    Diseases Database disease, symptom, sign, etc alphabetical index : L
    L-DOPA
    L-xylulose reductase deficiency see Hereditary pentosuria
    La Crosse virus see California encephalitis virus
    Lab abnormality (all) see Laboratory finding
    Labetalol

    Labhardt-Willi-Prader-Fanconi syndrome see Prader-Willi syndrome
    Laboratory finding

    Labour (normal)

    Labour dysfunction see Dystocia
    Labyrinthine fistula

    Labyrinthitis
    Lacidipine Lack of energy see Fatigue Lacrimal gland enlarged Lacrosse encephalitis see California encephalitis virus Lactase deficiency Lactate dehydrogenase Lactate dehydrogenase levels low (plasma or serum) ... Lactate dehydrogenase levels raised (plasma or serum) Lactate levels raised (plasma or serum) see Lactic acidosis Lacteal cyst see Galactocoele Lactic acidaemia see Lactic acidosis Lactic acidosis Lactitol Lactobacillus acidophilus ... Lactobacillus delbrueckii ss. bulgaricus Lactocele see Galactocoele Lactose intolerance see Lactase deficiency Lactosuria Lactulose Lacunar infarction see Lacunar stroke Lacunar stroke Lafora body disease Lamellar ichthyosis see Collodion baby syndrome Lamivudine Lamotrigine Lamoxactam see Moxalactam Landau-Kleffner syndrome Landouzy-Dejerine disease see Facio-scapulo-humeral muscular dystrophy Lange Nielsen syndrome Langer mesomelic dysplasia syndrome Langer-Giedion syndrome ... Langer-Saldino achondrogenesis Langerhan's cell histiocytosis see Histiocytosis X Lanreotide Lansoprazole Lanugo hair ... Laparotomy Large bowel cancer see Colorectal cancer Large bowel obstruction Large for dates

    49. Syndromes In Breast Cancer
    oral papules). It is also called as multiple hamartoma syndrome. PTENis a tumour suppressor gene located on 10q23 chromosome. The
    http://www.au-kbc.org/research_areas/bio/projects/bcinfo/gen/synd.html
    AU-KBC RESEARCH CENTRE
    Syndromes associated with breast cancer
    The incidence of syndrome associated with breast cancer is very low (less than 1%). The various syndromes associated with breast cancer are:
    Li-Fraumeni syndrome:
    A large number of sporadic cancers are due to mutation in p53 but when this occurs in germline cells, it results in Li-Fraumeni syndrome. It is characterized by premenopausal breast cancer in combination with childhood soft tissue tumours, brain tumors, leukemia, lymphoma, and adrenocortical carcinoma. The probability that these individuals will develop breast cancer is 60% overall. Germline mutations are mostly seen in the exon 7 of p53 gene. [OMIM]
    Germline mutations in another gene, hCHK2, have been implicated in the etiology of one classical and two variant Li-Fraumeni families
    A detailed account of p53 is discussed here
    Cowden syndrome:
    It is an autosomal dominant syndrome characterized by hamartomatous lesions in the breast, GI tract (polyps), CNS (Central Nervous System), skin and mucosa, eyes, thyroid, genitourinary tract and bones. Germline mutations in the PTEN gene is responsible for this syndrome. Diagnosis is established through identification of characteristic skin lesions (acral keratosis, facial trichilemmomas, and oral papules). It is also called as multiple hamartoma syndrome. PTEN is a tumour suppressor gene located on 10q23 chromosome. The gene product of PTEN is a phosphatase which plays an important role in regulating cell growth. Mutation in PTEN gene results in loss of protein function leading to uncontrolled cell proliferation and hamartomatous growths.

    50. DINO - Language: Englisch - Health - Conditions And Diseases - M
    Translate this page Link verweist auf eine Haupt-Kategorie Multiple Chemical Sensitivity Dieser Linkverweist auf eine Haupt-Kategorie multiple hamartoma syndrome Dieser Link
    http://www.dino-online.de/dino_page_24b646b8cd0e55a69f5ef091dac92489.html
    Suche Profi-Suche Katalog Video ... Produkte Suchen: Web-Seiten Video Audio Bilder Produkte Schon gewusst? Hier suchen Sie in 2 Milliarden Webseiten. Live-Suche: Was suchen andere Dino-Besucher?
    You are here: DINO Language Englisch Health ... Conditions and Diseases M M Sprache/Language
    Categories MAC
    Machado-Joseph Disease
    Macular Degeneration
    Mad Cow Disease
    Madelung's Disease
    Malaria
    Male Turner Syndrome
    Malignant Atrophic Papulosis
    Malnutrition Mannosidosis Marburg Marfan Syndrome Marie-Sainton Disease Marinesco-Sjogren Syndrome Mayer Rokitansky Kuster Hauser Syndrome McArdle's Disease Measles, German Measles, Red Meckel-Gruber Syndrome Megaloblastic Anemia Meige Syndrome Melanoma Melorheostosis Menengitis, Cryptococcal Meniere's Disease Meningitis Menkes' Syndrome Menstrual Problems Mental Retardation Meralgia Paresthetica Mesothelioma Metachromatic Leukodystrophy Microphthalmia Microsporidiosis Migraine Miller Fisher Syndrome Minimal Change Disease Mitchell Disease Mitral Valve Disease Mitral Valve Prolapse Syndrome Mobius Syndrome Moersch-Woltmann Syndrome Mood Disorders Morvan Disease Mouth Cancer Moyamoya Disease MPS III MRKH Mucopolysaccharidosis 3 Multiple Chemical Sensitivity Multiple Hamartoma Syndrome Multiple Myeloma Multiple Personality Disorder Multiple Sclerosis Multiple System Atrophy Mumps Murmurs Muscle Disorders Muscular Dystrophies Myalgic Encephalomyelitis Mycoplasmal Myelitis Myelodysplastic Syndromes Myelosyringosis Myocardial Diseases Myocardial Infarction Myopathies Myotonic Dystrophy

    51. Irritation Fibroma
    may represent cases of familial fibromatosis, fibrotic papillary hyperplasia of thepalate, tuberous sclerosis, or multiple hamartoma syndrome (Cowden syndrome
    http://www.maxillofacialcenter.com/BondBook/softtissue/fibroma.html
    Irritation (Traumatic) Fibroma
    Quick Summary
    Introduction

    References

    Photos
    ...
    Prognosis

    Irritation fibromas under dentures are flat and "leaf-shaped."
    Quick Review for Patients
    The irritation fibroma is a painless, localized, mass-producing proliferation of dense fibrous "scar" tissue which can result from a single traumatic episode or from repeated, less severe traumatic episodes; chronic inflammation or infection may also produce a fibroma. The lesion can become more than 3 cm. in size but is usually less than 1 cm. It occurs at all ages and in both genders and specialized forms occur under dentures, along denture edges and on inflamed gingiva. The fibroma is best treated by conservative surgical or laser removal, with a small chance of recurrence should the originating irritation persist. There is no risk of malignant transformation. Top of This Page
    Introduction Note: click on underlined words for more detail or photos. Irritation fibroma

    52. THE LIGHTNING HYPERTEXT OF DISEASE.
    syndrome = Langer mesomelic dysplasia syndrome Hamartomatosis = Hamartosis Cowdensyndrome = multiple hamartoma syndrome Encephalotrigeminal angiomatosis
    http://www.pathinfo.com/cgi-bin/lh.cgi?tx=ballergerold

    53. GeneCard For PTEN
    the predominant phenotype for cs is multiple hamartoma syndrome, in many organ systemsincluding the breast (70% of cs patients), thyroid (4060%), skin, cns
    http://bioinfo.cnio.es/cgi-bin/db/genecards/carddisp?PTEN

    54. MUMS List Of Disorders - C
    Syndrome (7) * ; Cowden Syndrome (multiple hamartoma syndrome) (4)*; CranioFronto-Nasal Dysplasia (2); Craniodiaphyseal Dysplasia
    http://www.netnet.net/mums/mum_c.htm
    Return to MUMS Home Page
    MUMS:
    List of Disorders
    C
    Number in parentheses indicates number of matches.
    indicates there is a support group which covers that diagnosis.
    • C-PAP (14)
    • CATCH 22 Syndrome(DiGeorge+Velo-Cardio-Facial+Conotruncal) (5) *
    • CHARGE Syndrome (49) *
    • CHARGE-VATER Syndrome (2)
    • Calcium Deficiency (26)
    • Campomelic Dysplasia Syndrome (11) *
    • Camptodactyly (5)
    • Canavan's Leukodystrophy (3) * www.canavan.org/
    • Cancer (135) * www.cancer.org and www.candlelighters.org
    • Cancer, Acute Lymphatic Leukemia (ALL) (6)*
    • Cancer, Anoplastic Oligodendroglioma Tumor (1)
    • Cancer, Chordoma (Spinal Tumor) (1) *
    • Cancer, Ewings Sarcoma (6) *
    • Cancer, Ovaries (1) *
    • Cancer, Primary Neuroectodermal Tumor of the Spine (PNET) (2) *
    • Cancer, Rhabdomyosarcoma (4)*
    • Candida Yeast Infection (7)
    • Carbamyl Phosphate Synthetase Deficiency (CPS) (2) *
    • Carbohydrate-Deficient Glycoprotein Syndrome (CDGS) (8) *
    • Carbon Monoxide Poisoning (2)
    • Cardiac Pacemaker (23)
    • Cardio-Facio-Cutaneous Syndrome (19) **
    • Cardiomyopathy (36) * www.childrenscardiomyopathy.org

    55. Thyrolink - Recently Published Editions
    J Clin Endocrinol Metab 2000, 85 286 292. Mallory SB. Cowden Syndrome(multiple hamartoma syndrome). Dermatologic Clinics 1995, 13 27-31.
    http://www.thyrolink.com/literature/report2000_4/seite08.html
    References
  • Ball D.W., Baylin S.B., De Butros A.C. Medullary thyroid carcinoma, In : Werner and Ingbar’s The Thyroid, Eighth Edition. Braverman L.E. and Utiger R.E. (Eds). Lippincott-Williams-Wilkins, Philadelphia, 2000, 930- 943.
    Donovan D.T., Gagel R.F. Medullary thyroid carcinoma and the Multiple Endocrine Neoplasia Syndromes. In: Thyroid Diseases: endocrinology, surgery, nuclear medicine and radiotherapy, 2nd Edition, Falk. A (Ed) Lippincott-Raven. Philadelphia,1997: 619-644.
    Mathew C.G.P., Chin K.S., Easton D.F., Thorpe K., Carter C, Liou G.I., Fong S.L., Bridges C.D.B., Haak H, Nieuwenhuijzen Kruseman A.C., Schifter S., Hansen H.H, Telenius H., Telenius-Berg M., Ponder B.A.J. A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10. Nature 1987, 328: 527-528.
    Simpson NE, Kidd KK, Goodfellow PJ, Mc Dermid H, Myers S, Kidd JR. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature 1987, 328: 528-530.
    Donis-Keller H., Dou S., Chi D., Carlson K.M., Toshima K., Lairmore T.C., Howe J.R., Moley J.F., Goodfellow P., Wells S.A. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum Mol Genet 1993, 2: 851-856.
    Hofstra R.M, Landsvater R.M., Ceccherini I., Stulp R.P., Stelwagen T., Luo Y., Pasini B., Hoppener J.W.M., Ploos Van Amstel H.K., Romeo G, Lips C.J.M., Buys C.H.C.M. Amutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 1994, 367: 375-376.
  • 56. Inflammatory Papillary Hyperplasia
    inflammatory papillary hyperplasia verruca vulgaris multiple squamous papillomasoral mucosal lesions of Cowden´s or multiple hamartoma syndrome lesions of
    http://www.dental.mu.edu/oralpath/lesions/flphyp/inflamhyperplasia.htm
    Inflammatory Papillary Hyperplasia (Denture Papillomatosis) A reactive tissue growth that usually develops beneath a denture. Clinical Features:
    "raspbery" appearce (multiple small erythematous nodules) may become symptomatic with secondary infection of Candidia albicans occurs on the palate more common in patients who wear dentures continuously
    Differential Diagnosis: condyloma acuminatum inflammatory papillary hyperplasia verruca vulgaris multiple squamous papillomas pyostomatitis vegetans
    Tissue of Origin: mucosa
    Histologic Features:
    epithelium and connective tissue papillary configuration inflamed connective tissue inflammatory cells may penetrate epithelium
    Main Pathologic Process: benign hyperplasia and inflammation
    Treatment: removing appliances for prolonged periods of time and using tissue conditioner on the base of the dentures use of antifungal agent possible surgical intervention
    Prognosis: seldom resolves completely, fibrous tissue does not return to normal
    Webmaster
    © 2001 - Marquette University School of Dentistry - P.O. Box 1881 - Milwaukee, WI 53201-1881

    57. Mioti: Medical Condition
    Condition Cowden Disease. Cowden Disease (multiple hamartoma syndrome).Information from eMedicine. Cowden disease and the PTEN gene.
    http://www.mioti.com/cat/condition/condition.asp?Cat=CowdenDisease

    58. Hamartoma Syndrome, Multiple
    A collection of medical, dental and veterinary images for use in teaching. hamartoma syndrome, multiple
    http://www.brisbio.ac.uk/ROADS/subject-listing/hamartomasyndromemultiple.html
    A collection of medical, dental and veterinary images for use in teaching. Home About the Archive FAQ Terms and Conditions ... Help
    Hamartoma Syndrome, Multiple
    Cowden's syndrome Cowden's syndrome Cowden's syndrome

    59. Hamartome Multiple, Syndrome : Sites Et Documents Francophones
    Le mot clé hamartome multiple, syndrome hamartoma multiple, syndrome est présent au sein de plusieurs arborescences
    http://www.chu-rouen.fr/ssf/pathol/hamartomemultiplesyndrome.html
    Hamartome Multiple, Syndrome Menu général CISMeF Synonyme(s) cowden, maladie ; maladie cowden ; syndrome hamartome multiple
    Arborescence(s) hamartome multiple, syndrome hamartoma multiple, syndrome
    maladies et malformations congénitales, héréditaires et néonatales
    tumeurs Position du mot-clé dans l' (les) arborescence(s) : Vous pouvez consulter Ou consulter ci-dessous une sélection des principales ressources :
    guide ressources 20 janvier 2003
    courriel
    Menu général CISMeF Haut de page © CHU de Rouen . Toute utilisation partielle ou totale de ce document doit mentionner la source.

    60. HON - List Of Rare Diseases
    Hallermann's syndrome, HallervordenSpatz syndrome. hamartoma syndrome, multiple,Hand-Schueller-Christian syndrome. Hartnup Disease, Hemoglobinuria, Paroxysmal.
    http://www.hon.ch/HONselect/RareDiseases/
    List of rare diseases: English Deutsch Acrocephalosyndactylia
    Acrodermatitis
    ... HONewsletter http://www.hon.ch/HONselect/RareDiseases/index.html Last modified: Thu Sep 26 2002

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