41. Multiple System Atrophy multiple system atrophy. Back to previous level Olivopontocerebellar AtrophySearch PUBMED for Olivopontocerebellar Atrophy All Review Therapy Diagnosis. http://www.ohsu.edu/cliniweb/C10/C10.228.140.79.612.html

Multiple System Atrophy Back to previous level Olivopontocerebellar Atrophy Search PUBMED for Olivopontocerebellar Atrophy: All Review Therapy Diagnosis Parkinson Disease Search PUBMED for Parkinson Disease: All Review Therapy Diagnosis ... Young-Onset Parkinson's Disease: Harvard U. Shy-Drager Syndrome Search PUBMED for Shy-Drager Syndrome: All Review Therapy Diagnosis

42. Arch Otolaryngol Head Neck Surg -- Page Not Found Bilateral Vocal Fold Paresis and multiple system atrophy Author InformationJoel H. Blumin, MD; Gerald S. Berke, MD Objective To http://archotol.ama-assn.org/issues/v128n12/abs/ooa20067.html

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

43. Multiple System Atrophy multiple system atrophy. Definition Causes, incidence, and risk factorsmultiple system atrophy (MSA) is a rare degenerative condition. http://www.pennhealth.com/ency/article/000757.htm

Disease Injury Nutrition Poison ... Prevention Multiple system atrophy Definition: A degenerative disorder characterized by progressive damage to the autonomic nervous system (the portion of the nervous system that controls involuntary functions such as blood pressure, heart rate, digestion and sexual function), muscle tremor and rigidity, slow movement, and other widespread neurologic losses. Alternative Names: Shy-Drager Syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome Causes, incidence, and risk factors: Multiple system atrophy (MSA) is a rare degenerative condition. It is a condition that appears similar to Parkinson's disease in that patients may be slow moving, tremulous and have a shuffling gait but with more widespread neurologic damage and damage to the autonomic nervous system (the portion of the nervous system that controls involuntary functions). The cause is unknown. There is progressive damage (degeneration) of the nervous system, with damage to all parts of the nervous system. The disorder develops gradually. It is most often diagnosed in men over 60 years old. Review Date: 6/10/2001 Reviewed By: Galit Kleiner-Fisman, M.D., Department of Neurology, Beth-Israel Deaconess Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network.

44. Multiple System Atrophy multiple system atrophy. Alternative Names ShyDrager Syndrome; Neurologic orthostatichypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome. http://www.pennhealth.com/ency/article/000757sym.htm

Disease Injury Nutrition Poison ... Prevention Multiple system atrophy Alternative Names: Shy-Drager Syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome Symptoms: Dizziness or fainting when arising or after standing still Impotence Loss of sweating of any part of the body Loss of control of bowels or bladder Vision changes, decreased or blurred vision Muscle rigidity Stiffness Difficulty bending arms or legs Posture may be unstable, stooped, or slumped over Movement difficulties Loss of balance Gait (walking pattern) changes Shuffling Slow movements Difficulty beginning to walk, difficulty initiating any voluntary movement Small steps followed by the need to run to maintain balance Freezing of movement when the movement is stopped, unable to resume movement Muscle aches and pains ( myalgia Tremors (may present in varying degrees, may not be present) May occur at rest or at any time May become severe enough to interfere with activities May be worse when tired, excited, or stressed Finger-thumb rubbing (pill rolling tremor ) may be present May occur with any action such as holding a cup or other eating utensils Changes in facial expression Reduced ability to show facial expressions "Mask" appearance to face Staring May be unable to close mouth Voice and/or speech changes Slow speaking Voice is low-volume Monotone Difficulty speaking Difficulty chewing or swallowing (occasionally) Loss of fine motor skills Difficulty writing, may be small and illegible

45. Multiple System Atrophy Chat Room multiple system atrophy Chat Room CHAT TIMES Eastern, Central, Mountain, Pacific,GMT/UTC. WEEKDAYS, 1 PM, NOON, 11 AM, 10 AM, 5 PM. SUNDAY, 3 PM, 2 PM, 1 PM, NOON,7 PM. http://www.accesswave.ca/~pbower/msachat.htm

Multiple System Atrophy Chat Room CHAT TIMES: Eastern Central Mountain Pacific GMT/UTC WEEKDAYS 1 PM NOON 11 AM 10 AM 5 PM SUNDAY 3 PM 2 PM 1 PM NOON 7 PM WEDNESDAY 7:30 PM 6:30 PM 5:30 PM 4:30 PM 11:30 PM Australians can join us on THURSDAYS at 9:30 AM Sydney time To enter the chat room click on "Join my Chat Room" below. NOTE: You must be running Instant Messenger software. If you don't have the software click on " Download Instant Messenger" below or click on the orange stickman icon. Download Instant Messenger NEW: Send an Instant Message from this page. (You must have AIM running for this to work.) ScreenName to Send to: Message: Just Enter Your Message Here! Don't forget to join the Multiple System Atrophy Online Support Group! Click to join We welcome patients and families and friends of those with ANY neurodegenerative disorder. ESPECIALLY: MSA SDS SND OPCA CBGD PSP LBD PAF POTS Multiple System Atrophy Shy-Drager Syndrome Striatonigral Degeneration Olivopontocerebellar Atrophy Corticobasal Ganglionic Degeneration Progressive Supranuclear Palsy Lewy Body Dementia Pure Autonomic Failure Postural Orthostatic Tachycardia Syndrome Send questions or feedback to: pbower@accesscable.net

46. Health Ency.: Disease: Multiple System Atrophy Ency. home Disease M multiple system atrophy. multiple system atrophy. Causesand Risks. multiple system atrophy (MSA) is a rare degenerative condition. http://www.austin360.com/shared/health/adam/ency/article/000757.html

SEARCH: The Web Yellow Pages HOME Illustrated Health Encyclopedia Important notice Ency. home Disease M Multiple system atrophy Overview Symptoms Treatment Prevention Alternative names: Shy-Drager Syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome Definition: A degenerative disorder characterized by progressive damage to the autonomic nervous system (the portion of the nervous system that controls involuntary functions such as blood pressure, heart rate, digestion and sexual function), muscle tremor and rigidity, slow movement, and other widespread neurologic losses. Causes and Risks Multiple system atrophy (MSA) is a rare degenerative condition. It is a condition that appears similar to Parkinson's disease in that patients may be slow moving, tremulous and have a shuffling gait but with more widespread neurologic damage and damage to the autonomic nervous system (the portion of the nervous system that controls involuntary functions). The cause is unknown. There is progressive damage (degeneration) of the nervous system, with damage to all parts of the nervous system. The disorder develops gradually. It is most often diagnosed in men over 60 years old. Ency. home

47. Health Ency.: Disease: Multiple System Atrophy notice. Ency. home Disease M multiple system atrophy. Multiple systematrophy. Ency. home Disease M multiple system atrophy. Please http://www.austin360.com/shared/health/adam/ency/article/000757sym.html

SEARCH: The Web Yellow Pages HOME Illustrated Health Encyclopedia Important notice Ency. home Disease M Multiple system atrophy Overview Symptoms Treatment Prevention Alternative names: Shy-Drager Syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome Symptoms Dizziness or fainting when arising or after standing still Impotence Loss of sweating of any part of the body Loss of control of bowels or bladder Vision changes, decreased or blurred vision Muscle rigidity Stiffness Difficulty bending arms or legs Posture may be unstable, stooped, or slumped over Movement difficulties Loss of balance Gait (walking pattern) changes Shuffling Slow movements Difficulty beginning to walk, difficulty initiating any voluntary movement Small steps followed by the need to run to maintain balance Freezing of movement when the movement is stopped, unable to resume movement Muscle aches and pains ( myalgia Tremors (may present in varying degrees, may not be present) May occur at rest or at any time May become severe enough to interfere with activities May be worse when tired, excited, or stressed

48. Nature Publishing Group Guest editorial. Lewy body diseases and multiple system atrophy as synucleinopathies.M Goedert 1,a and MG Spillantini 2. 1 MRC Laboratory http://www.nature.com/cgi-taf/DynaPage.taf?file=/mp/journal/v3/n6/abs/4000458a.h

49. Nature Publishing Group and neuropathological phenotype displayed by 1B AR transgenic mice are consistentwith the autonomic (Shy–Drager) presentation of multiple system atrophy (MSA http://www.nature.com/cgi-taf/DynaPage.taf?file=/nm/journal/v7/n2/full/nm0201_13

50. The Family Village - Shy Drager Syndrome Shy Drager Syndrome. Synonym multiple system atrophy. ShyDrager Syndrome/MultipleSystem Atrophy Support Group (SDS/MSA) 2004 Howard Lane Austin, TX. http://www.familyvillage.wisc.edu/lib_shyd.htm

Shy Drager Syndrome Synonym: Multiple System Atrophy Who to Contact Where to Go to Chat with Others Learn More About It Web Sites ... Search AltaVista for "Shy Drager Syndrome" Who to Contact Shy-Drager Syndrome/Multiple System Atrophy Support Group (SDS/MSA) 2004 Howard Lane Austin, TX. 78728 Toll Free: 1-866-SDS-4999 (Answering Machine) Phone: 512-251-2247 (Weekdays) 512-856-2427 (Nights and Weekends) Fax: 512-251-3315 E-mail: shydrager@yahoogroups.com Web: http://www.shy-drager.com/ Newsletter Subscription Requests: shydrager-subscribe@yahoogroups.com Where to Go to Chat with Others ShyDrager Discussion List http://groups.yahoo.com/group/shydrager Learn More About It Shy-Drager Syndrome Mini Fact Sheet Multiple System Atrophy (MSA) Shy-Drager Syndrome Medical College of Wisconsin Physicians and Clinics Multiple System Atrophy From the We Move Web Site Web Sites Shy-Drager Syndrom/Multiple System Atrophy Web Site Charmayne's Multiple System Atrophy / Shy-Drager Pages Back to [ S - T Family Village Home Library Coffee Shop ... Information Last Updated 4/30/2001 by familyvillage@waisman.wisc.edu

51. ORPHANET® : Multiple System Atrophy Translate this page ORPHANET. ORPHANET database access. multiple system atrophy. Directaccess to details Alias Shy-Drager syndrome. Home Page. http://www.orpha.net/static/GB/multiple_system_atrophy.html

ORPHANET database access Multiple system atrophy Direct access to details Alias : Home Page

52. Multiple System Atrophy Syndromes Information Page Diseases Database multiple system atrophy syndromes Information Page. multiple system atrophysyndromes Gomultiple system atrophy syndromes specific sites. http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=8441

53. Multiple System Atrophy : Meddie Health Search ITEMS LINKS Keynote Lecture on MSA by PL Lantos Cellular and Molecular Pathologyof multiple system atrophy A Review and Recent Developments. http://www.meddie.com/search/Health/Conditions_and_Diseases/Neurological_Disorde

HOME ADD A LINK MODIFY A LINK NEW LINKS ... TOP RATED Search Meddie: the entire directory only this category More search options Home Health Conditions and Diseases ... Neurodegenerative Diseases : Multiple System Atrophy ITEMS: LINKS: Keynote Lecture on MSA by P. L. Lantos Cellular and Molecular Pathology of Multiple System Atrophy: A Review and Recent Developments. (Rating: 0.00 Votes: 0) Rate It Multiple System Atrophy Articel by Timothy C. Hain, MD Northwestern University Medical School, Chicago. (Rating: 0.00 Votes: 0) Rate It Multiple System Atrophy Good Article on MSA by the National Parkinson Foundation. (Rating: 0.00 Votes: 0) Rate It Multiple System Atrophy - NeurologyChannel Good article on MSA including MSA anatomy. (Rating: 0.00 Votes: 0) Rate It National Dysautonomia Research Foundation MSA NDRF provides patient support, medical referral, educational material, newsletters, an online discussion forum and a research protocol database for individuals impacted with dysautonomic disorders. (Rating: 0.00 Votes: 0) Rate It The Parkinson's Institute - Multiple System Atrophy Short article on clinical presentation and treatment. (Rating: 0.00 Votes: 0)

54. Multiple System Atrophy only one click For Medical Professionals only. Multiple systematrophy,, Print this article, condition belonging to the group of http://www.amershamhealth.com/medcyclopaedia/Volume VI 1/MULTIPLE SYSTEM ATROPHY

Medcyclopaedia About Medcyclopaedia Amersham Health Search for: Type a word or a phrase. All forms of the word are searchable. Advanced search Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search *For Medical Professionals only, registration required Multiple system atrophy, condition belonging to the group of neurodegenerative disorders with prevalent degeneration of the substantia nigra and related systems, and Parkinsonism. There are four main variants: striatonigral degeneration Shy Drager syndrome olivopontocerebellar atrophy ; and Parkinsonism and motor neurone diseases. GS The Encyclopaedia of Medical Imaging Volume VI:1 Welcome to Medcyclopaedia. This site is open to a public audience, still we want to know a little more about our visitors. Please tick off the boxes that match your profile. Do you live in Europe? Yes No Are you a medical professional?

55. Multiple System Atrophy News - September 2002 multiple system atrophy News September 2002. 2. multiple system atrophy IN THEMEDIA a. About Health TV Interview on MSA featuring Tony Swartz-Lloyd. http://www.parkinson.ca/board/messages/1655.html

Multiple System Atrophy News - September 2002 Follow Ups Post Followup Parkinson's Discussion Forum FAQ Posted by Pam Bower on August 30, 2002 at 10:20:47: Multiple System Atrophy News - September 2002 Table of Contents 1. SUPPORT GROUP EVENTS a. SDS/MSA Regional Conference: Chicago IL - September 13 - 15, b. All California Ataxia Research Meeting: Fresno, CA - November 2. MULTIPLE SYSTEM ATROPHY IN THE MEDIA a. "About Health" TV Interview on MSA featuring Tony Swartz-Lloyd 3. MULTIPLE SYSTEM ATROPHY RESEARCH NEWS a. Vanderbilt team nets $9.5 million to study autonomic nervous system 4. ODDS AND ENDS a. Local MSA Support Groups 1. SUPPORT GROUP EVENTS a. SDS/MSA Regional Conference: Chicago IL - September 13 - 15, 2002 The Chicago SDS/MSA Support Group meeting arrangements have been completed. Location: The Chicago O'Hare Hilton Hotel Dates: Friday, Sept.13 through Sunday Sept. 15th Room rates: $90.00 plus tax per night Accessibility: Walking (Tunnel) from Baggage claim or via Hilton courtesy shuttle outside baggage claim area. Hotel reservation Instructions: Call 877-865-5322 The group code is SDS/MSA. The code (including the "slash") must be

56. Re: Multiple System Atrophy News - March 2002 Re multiple system atrophy News March 2002. In Reply to multiple system atrophyNews - March 2002 posted by Pam Bower on March 21, 2002 at 114855 http://www.parkinson.ca/board/messages/1532.html

Re: Multiple System Atrophy News - March 2002 Follow Ups Post Followup Parkinson's Discussion Forum FAQ Posted by Susan Campbell on May 01, 2002 at 00:16:15: In Reply to: Multiple System Atrophy News - March 2002 posted by Pam Bower on March 21, 2002 at 11:48:55: I am looking for a support group in Canada and I am always successful in finding them in the USA but not in Canada. My mother was diagnosed with MSA about 2 months ago and I have been studying everything I can find on the internet about MSA. I would love to find somewhere in Canada that would have a Patient Conference or Support Groups of some kind.I Thank-You for any information you can give me. Follow Ups: Re: Multiple System Atrophy News - March 2002 Pam Bower Post a Followup Name: E-Mail: Subject: Comments: Optional Link URL: Link Title: Optional Image URL: Follow Ups Post Followup Parkinson's Discussion Forum FAQ

57. Other Ataxias Other Ataxias and related disorders. multiple system atrophy (MSA) August 1994.Brain Clinical features and natural history of multiple system atrophy. http://internaf.org/ataxia/othatax.html

Other Ataxias and related disorders Multiple System Atrophy (MSA): http://www.ndrf.org/MSA.htm June 1997 Acta Neuropathol: The distribution and dynamic density of oligodendroglial cytoplasmic inclusions (GCIs) in multiple system atrophy August 1994 Brain: Clinical features and natural history of multiple system atrophy. Ananalysis of 100 cases. November 1993 Nippon Rinsho: Multiple system atrophy (MSA) MSA with Cerebellar Ataxia - "Sporadic Olivopontocerebellar Atrophy" (OPCA): NINDS Pamphlet - Olivopontocerebellar Atrophy (OPCA) January 1997 Movement Disorders: Cerebellar presentation of multiple system atrophy. March 1996 Movement Disorders: Olivopontocerebellar pathology in multiple system atrophy. MSA With Autonomic Failure - "Shy-Drager Syndrome" (SDS): Jeff's Shy-Drager Page Shy-Drager Syndrome American Autonomic Society CWRU Autonomic Labratory June 1997 Axone: Shy-Drager Syndrome March 1997 New England Journal of Medicine: Autonomic Disorders and Their Recognition MSA with "Striatonigral Degeneration" (SND): January 1997 Nippon Rinsho: Striatonigral Degeneration Episodic Ataxia (EA): Episodic Ataxia Information by Mark Dias OMIM entry for Episodic Ataxia Type 1 OMIM entry for Episodic Ataxia Type 2 OMIM entry for CSE (Choreoathetosis with Spasticity and Episodic Ataxia) Autosomal Recessive Spastic Ataxia of Charelevoix-Saguenay (ARSACS):

58. Multiple System Atrophy - General Practice Notebook multiple system atrophy. Three Pathologically multiple system atrophy ischaracterised by widespread neuronal loss and gliosis. Clinically http://www.gpnotebook.co.uk/cache/-241565650.htm

multiple system atrophy Three neurodegenerative disorders are included under this heading: olivopontocerebellar atrophy (OPCA) strionigral degeneration Shy-Drager syndrome Pathologically multiple system atrophy is characterised by widespread neuronal loss and gliosis. Clinically there are three distinct pictures according to which parts of the brain are most severely affected: cerebellar ataxia in OPCA Parkinsonism in strionigral degeneration autonomic failure in Shy-Drager syndrome Click here for more information...

59. Multiple System Atrophy (congenital) - General Practice Notebook multiple system atrophy (congenital). multiple system atrophy usuallyautosomal recessive; prognosis is poor with early onset disease; http://www.gpnotebook.co.uk/cache/-167378898.htm

multiple system atrophy (congenital) These are a heterogeneous group of ataxias caused by: malformation and hypoplasias of the cerebellum: usually autosomal dominant inheritance onset during childhood characterised by hypotonia and cerebellar ataxia IQ is normal good prognosis, some improve with age multiple system atrophy: usually autosomal recessive prognosis is poor with early onset disease characterised by: spasticity failure to thrive amyotrophy skeletal malformations babies die within a few weeks of birth Click here for more information...

60. MSA multiple system atrophy. multiple system atrophy Clinical Diagnostic Criteria.Striato Nigral Degeneration Type. (predominant parkinsonism). http://www.cmdg.org/Movement_/Parkinsons_Plus/MSA/msa.htm

Multiple System Atrophy This term abbreviated MSA defines a specific syndrome within the larger less well defined category of multiple system degenerations. The features of the MSA include: parkinsonism, cerebellar or corticospinal signs, orthostatic hypotension, impotence, and urinary incontinence or retention, usually preceding or within two years after the onset of the motor symptoms. The previous division into Shy Drager Syndrome (SDS), Striato Nigral Degeneration (SND), and Olivopontocerebellar Atrophy (OPCA) has been dropped. Immunohistochemistry demonstrates that these three disorders share a common pathology. The latest diagnostic criteria are shown in the table below. Wenning et. al. determined that the combination of autonomic insufficiency, speech or bulbar dysfunction, absence of dementia, postural instability with falls, poor response to levodopa, and absence of levodopa-induced confusion gave a diagnostic sensitivity and specificity greater than 90%. Median age of onset of MSA is about age 55 years (range of 33 to 76). It affects men slightly more than women. Nearly half of patients are disabled or wheelchair bound within 5 years of the onset of motor symptoms. Mean survival is 6 to 7 years. 80% of MSA patients develop predominant parkinsonism (MSA-P) and 20% develop predominant cerebellar signs (MSA-C). The latter statistics are likely skewed by referral patterns to movement disorder centers. There is considerable overlap. Cerebellar features are present in over 40% of patients with SND type, and parkinsonism is detectable in 50% of OPCA type patients.

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