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         Non-hodgkins Lymphoma:     more books (101)
  1. Non-Hodgkin's Lymphomas
  2. Hodgkin's and Non-Hodgkin's Lymphoma (Cancer Treatment and Research)
  3. Non-Hodgkin Lymphomas
  4. Non-Hodgkin's Lymphomas: Making Sense of Diagnosis, Treatment and Options by Lorraine Johnston, 1999-05-15
  5. The Official Patient's Sourcebook on Non-Hodgkin's Lymphoma During Pregnancy: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-12
  6. Hodgkin's Disease and Non-Hodgkin's Lymphoma: New Perspectives in Immunopathology, Diagnosis, and Treatment (Ut M. D. Anderson Clinical Conference O)
  7. Hodgkin's Disease and Non-Hodgkin's Lymphomas in Adults and Children
  8. WHAT YOU NEED TO KNOW ABOUT NON-HODGKIN LYMPHOMA by US DEPT OF HUMAN SERVICES, 2007
  9. UNDERSTANDING NON-HODGKIN'S LYMPHOMAA GUIDE FOR PATIENTS by LYMPHOMA RESEARCH-FOUNDATION, 2004
  10. The Official Parent's Sourcebook on Childhood Non-Hodgkin's Lymphoma: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-11
  11. Histopathology of Non-Hodgkin's Lymphomas (Based on the Updated Kiel Classification) by Alfred C. Feller, Jacques Diebold, et all 2004-02-09
  12. The Official Patient's Sourcebook on Adult Non-Hodgkin's Lymphoma: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-11
  13. Hodgkin's and Non-Hodgkin's Lymphomas (Seminars in oncology)
  14. Non-Hodgkin's Lymphoma - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Health Publica Icon Health Publications, 2003-11-13

1. Www.patientcenters.com -- Non-Hodgkin's Lymphoma Center
nonhodgkins lymphoma. This refers to any group of cancers of lymphoid tissue that multiply unchecked.
http://www.patientcenters.com/lymphoma

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Non-Hodgkin's Lymphomas Live Longer, Live Larger give tools to patients for thriving with cancer: Researching NHL. This article discusses how to get information from NCI, the internet, and medical research papers and textbooks; how to find out about clinical trials and support groups; and how to verify chemotherapy doses, interpret test results, and assess unproven remedies. If you are keeping up with all lymphoma research, ACOR (Association of Cancer Online Resources) now has a search feature to scan the MedLine literature for recent additions in a particular disease type. For recent articles, it's easier than searching MedLine because you don't have to go in and set search limits/dates. If You're Hospitalized. There are precautions you can take to make a hospital stay shorter and more effective. Make the best of your stay with these tips. Treating NHL: Specific Classifications.

2. Lymphoma And Leukemia Care - Articles And Webcasts On Non Hodgkins Lymphoma, CLL
A lymphocytic leukemia and nonhodgkins lymphoma cancer resource which is oriented to treatment options.
http://www.llcare.org
Lymphoma and Leukemia Care
Non-Hodgkins Lymphoma Leukemia Resources
Welcome to Leukemia and Lymphoma Care
Today, more people are surviving leukemia and lymphoma than ever before, and the prognosis is steadily improving. The goal of LLCare is to inform and educate people with leukemia and lymphoma about new targeted therapies which not only improve treatment success but also quality of life.
Leukemia and Lymphoma Information Center
- Over 50,000 Americans are diagnosed with non-hodgkins lymphoma each year
- Over 300,000 people in the U.S. are living with non-hodgkins lymphoma
- Over 30,000 Americans are diagnosed with leukemia each year Receive Free Information on
Non-Hodgkins Resources
Leukemia Resources About LLCare ... Contact Us

3. Medical Considerations NON-HODGKINS LYMPHOMA
CLINICAL MANAGEMENT OF THE HIVINFECTED ADULT non-hodgkins lymphomas (NHL) are a heterogeneous group of malignant neoplasms. Their cause is unknown.
http://www.hivdent.org/medmid/middsp020.htm
www.HIVdent.org Medical Considerations
CLINICAL MANAGEMENT OF THE HIV-INFECTED ADULT
Disease-Specific Protocols
NON-HODGKINS LYMPHOMA NON-HODGKINS LYMPHOMA Definition: Non-Hodgkins lymphomas (NHL) are a heterogeneous group of malignant neoplasms. Their cause is unknown. High-grade B-cell NHL is an AIDS-indicator condition, as is primary CNS lymphoma (with or without documented HIV infection). While many HIV-infected NHL patients present with a history of generalized lymphadenopathy, AIDS-related NHL is frequently an extranodal disease. Often disease is advanced at the time of presentation, with involvement of the bone marrow, CNS, GI tract, or liver. As patients with advanced HIV disease live longer, their risk for HIV-related neoplasms may increase. Lymphoma should be suspected in patients with advanced HIV disease who develop new adenopathy. S: Non-CNS: Patient complains of node swellings accompanied by persistent fevers, night sweats or weight loss; gastrointestinal bleeding; persistent perirectal pain; bony pain or tenderness; jaundice or light-colored stools. CNS (25% of reported cases): Patient complains of confusion, lethargy, memory loss, hemiparesis, aphasia, seizures, headaches, cranial nerve palsies.

4. GMHC: Fact Sheet -- AIDS-Related Non-Hodgkins Lymphoma (NHL)
AIDSRelated non-hodgkins lymphoma (NHL) What is non-hodgkins lymphoma (NHL)? NHL is the most common of all lymphomas that affects people with HIV. Lymphomas are cancerous tumors of the lymphatic system.
http://www.gmhc.org/living/treatment/lymph.html
AIDS-Related Non-Hodgkins Lymphoma (NHL)
What is Non-Hodgkins Lymphoma (NHL)?
NHL is the most common of all lymphomas that affects people with HIV. Lymphomas are cancerous tumors of the lymphatic system. The lymphatic system is a part of the immune system that defends the body against disease. NHL occurs when the body's B-cells or T-cells (types of white blood cells) start growing and dividing abnormally causing tumors to develop. NHL is separated into two major categories: systemic lymphomas and primary central nervous system (CNS) lymphomas. Systemic lymphomas occur mostly in people with CD4 counts over 50. CNS lymphomas occur mostly in people with CD4 counts 50 and under and who have had other opportunistic infections. In people with HIV, NHL often develops outside the lymph nodes, including the liver, bone marrow, stomach, brain, mouth and anus. What are the Signs and Symptoms of NHL?
Swollen lymph nodes are the most common sign of NHL. Other symptoms include fevers, weight loss, fatigue, rectal pain, abnormal pain or vomiting. People with CNS lymphoma can develop confusion, loss of memory or speech, changes in personality, seizures, headaches or partial paralysis. Some of these symptoms could be caused by other HIV-related conditions. However, if these symptoms last for more than a week, see a doctor immediately because NHL can grow very rapidly. How is NHL Diagnosed?

5. The Cancer Infomation Network
Provides general overview information and internet resources links on nonhodgkins lymphoma.
http://www.thecancer.info/lymphoma/
Thank You For Visiting Our Site! Home Support Top 10 Prevention ... Message Board
First Steps After Diagnosis of Cancer
Top 10 Cancer Sites, Treatment Centers, and Cancer Books for Newly Diagnosed Patients. Cancer Patients: Known Your Rights. Understanding Prognosis and Cancer Statistics - answers the most important question, "What is my prognosis?" Support Groups for Cancer Patients ... Pediatric Cancers Welcome to The Cancer Information Network Introduction
Non-Hodgkin's Lymphoma is a group of malignant diseases develops from the lymphatic system. This year, more than 50,000 people will be diagnosed with this malignancy. The diagnosis of NHL brings with them many questions and a need for clear, understandable answers... In The Spotlight: Late Effects in Long-Term Survivors of Non- Hodgkin Lymphomas Selective medical literature for patients.

6. Understanding Non-Hodgkins Lymphomas - Introduction, Understanding Non Hodgkins
Online booklet addressing the diagnosis and treatment of nonHodgkin's lymphoma.Category Health Conditions and Diseases Lymphoma Non-Hodgkin s......Information on non Hodgkins lymphoma including diagnosis andtreatment, chemotherapy, radiotherapy, and surgery.
http://www.cancerbacup.org.uk/info/nhl.htm
The UK's Leading Cancer Information Service FREEPHONE HELPLINE: 0808 800 1234 Cancer
Information
Clinical ... References
Understanding Non-Hodgkin's Lymphomas (NHL) From the CancerBACUP booklet series Booklet revised: November 2002 Introduction This booklet has been written to help you understand more about non-Hodgkin's lymphomas (NHL). Non-Hodgkin's lymphomas are cancers of the lymphatic system. We hope that this booklet answers some of the questions you may have about their diagnosis and treatment. We cannot advise you about the best treatment for yourself because this information can only come from your own doctor, who is familiar with your full medical history. At the end of this booklet you will find some useful addresses and helpful books . If, after reading this booklet, you think it has helped you, do pass it on to any of your family and friends who might find it useful. They too may want to be informed so they can help you cope with any problems you may have. Non-Hodgkin's lymphomas can occur in children as well as adults and some of the information in this booklet will help parents who want to understand more about their child's illness. CancerBACUP has a booklet specifically on childhood cancer that has information about NHL in children:

7. Usenet Creator Jim Ellis Dies
USA Today's tribute to the creator of Usenet, who died from nonhodgkins lymphoma.
http://www.usatoday.com/life/cyber/tech/2001-06-29-ellis-usenet.htm
Home News Money Sports ... Tech Main Categories Tech briefs Web Guide Tech Investor Product reviews More Tech Columnists Shareware Shelf Talk Today Weather Site Web
Click here to get the Daily Briefing in your inbox
06/29/2001 - Updated 12:03 PM ET Usenet creator Jim Ellis dies Ellis, who had been battling non-Hodgkins lymphoma for two years, died at home in Beaver County early Thursday, said his wife, Carolyn. Most recently an Internet security consultant with Sun Microsystems, Ellis was one of the creators of Usenet, which linked computers and allowed people to share information and reply to messages. Usenet began in 1979 when Ellis and another Duke graduate student, Tom Truscott, thought of hooking together computers to share information. At the beginning of 1980, the network consisted of two sites at Duke and one at the University of North Carolina. Usenet quickly became a popular means of trading and sharing information internationally before the World Wide Web came into existence. Allan Fisher, chief executive officer of Carnegie Technology Education, a subsidiary of Carnegie Mellon University which develops Web-based courses, said Usenet could be considered "the first big community application" of an interconnected system of computers.

8. Non-Hodgkin's Lymphoma
Information on non Hodgkins lymphoma including diagnosis and treatment, chemotherapy, radiotherapy, and surgery.
http://www.healthgoods.com/education/health_information/cancer_rates_and_risks/n
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Non-Hodgkin's Lymphoma
Sheila Zahm, Ph.D. Lymphomas are cancers that affect the white blood cells of the immune system. They are characterized by the abnormal growth of lymphocytes, the infection-fighting cells in the lymph nodes, spleen, and thymus. The tonsils, stomach, small intestine, and skin may also be affected. Primary lymphomas of the skin such as mycosis fungoides and Sezary's disease are extremely rare. Burkitt's lymphoma, rare in most of the world, is the most common childhood cancer in Central Africa, and is one of the most aggressive of all human cancers. Lymphomas are usually classified as Hodgkin's disease or non-Hodgkin's lymphoma. An estimated 45,000 new cases of non-Hodgkin's lymphoma were diagnosed in the United States in 1994 (Boring et al., 1994). Incidence per 100,000 is 18.6 among white males, 12.0 among white females, 12.8 among black males, and 8.1 among black females. In the United States, five-year survival is 53 percent for white patients and 45 percent for black patients. The highest incidence rates internationally for non-Hodgkin's lymphoma were observed for the United States and Canada (Parkin et al., 1992), although comparing incidence, survival, and mortality statistics among countries may be difficult because of differing classification systems used for these diseases. Between 1973 and 1991, the 73 percent increase in the incidence of non-Hodgkin's lymphoma was one of the largest among the major cancer sites in the United States (Ries et al., 1994). Part of the increase in incidence of non-Hodgkin's lymphoma in recent years has been related to AIDS. Non-Hodgkin's lymphoma is about 60 times more common in AIDS patients than in the general U.S. population (Beral et al., 1991). Gail et al. (1991) estimated that between 8 and 27 percent of all non-Hodgkin's lymphoma cases that occurred in the United States in 1992 were a direct consequence of infection with human immunodeficiency virus (HIV). AIDS, however, cannot explain the increase in non-Hodgkin's lymphoma observed over a period that began years before the AIDS epidemic surfaced, and continues to be observed in the absence of HIV infection.

9. ADAP Drugs: Sargamostrim
Used to treat nonhodgkins lymphomas and acute leukemia. (Leukine, Prokine, GM-CSF)
http://www.atdn.org/access/drugs/sarg.html
sargramostim
(Leukine, Prokine, GM-CSF) Drug description
Side effects
Possible side effects include headaches, fevers and flushing. In using sargramostim to treat people with HIV infection, there is concern that sargramostim may help spread HIV further throughout the body. Sargramostim stimulates macrophages, a crucial part of the immune system, and macrophages may be infected with HIV. Dosage
Sargramostim is given by IV injection over 2 hours. How long it may take to work
Sargramostim treatment for individuals who have had bone marrow transplants is for 14 days and then discontinued for 7 days. If after this 7 day period, the graft has still not taken, a second 14 day course of treatment may be given. Dose may be increased for a third course of treatment, but if no improvement is seen after the third course of sargramostim therapy, alternative treatment will be necessary. Managing side effects
If malignancy progression is observed during treatment, the drug should be discontinued. If severe adverse reaction occurs, dosage of the drug should be reduced or temporarily discontinued. This information is specific to the use of this medication for HIV-related conditions. For additional information about this drug for other conditions, refer to:

10. New Page 1
Dedicated to the life of our son and brother who passed away at the age of 11 after a heroic battle with nonhodgkins lymphoma.
http://www2.netsell.com/schneider/
June 20th - 3rd Anniversary of David's passing - Forever in our hearts... Forever on our minds Welcome to our Memorial home page dedicated to our son and brother David. We are the Schneider family, living in Southern Ontario, Canada. Let us introduce ourselves. Joyce Schneider is a high school teacher of Drama and Performing Arts. Her spouse, Michael, is a teacher in the same school, head of the same department, and teaches English as well as Drama and Performing Arts. As you can see, we have absolutely nothing in common! Our beautiful daughter, Mary, is 16 years old. She is an accomplished dancer and baseball player, loves acting and singing, and is now finishing grade 11 at her mom and dad's school, and loves it. Our boy David passed away on June 20th 1998 after a long and struggle with non-Hodgkin’s’ lymphoma at the age of 11. This Web sight was intended in part to be a celebration of his life and we are grateful that he was able to participate in its creation. It is our David who greets you when you click on the " Cat Gallery " link, along with his beloved Butterscotch; it was recorded just 4 days prior to his passing. We have a separate page detailing David’s

11. OncoLink
Search the Library Search all of OncoLink Advanced Search. OncoLink Library. OncoLinkLibrary Journal Scans nonhodgkins lymphoma. non-hodgkins lymphoma.
http://www.oncolink.com/library/section.cfm?c=2&s=37

12. Lymphoma Focus - Educational Resources About Hodgkins Disease,
Lymphoma articles and videos about treatment of Hodgkins disease and nonhodgkins lymphoma.
http://redirect-west.inktomi.com/click?u=http://www.lymphomafocus.org/&y=0226880

13. Lymphoma Focus - Educational Resources About Hodgkins Disease, Non-hodgkins Lymp
Resource for many aspects of lymphoma, including Hodgkins disease, Bcell lymphoma, and non-hodgkins lymphoma. Information on the symptoms, diagnosis, treatment, and webcasts.
http://www.lymphomafocus.com
A Comprehensive Educational Resource for the Lymphoma Community Lymphoma strikes men, women and children of all ages. More accurate diagnosis and effective treatments have improved the long-term outlook for many people with Hodgkins and non-Hodgkins lymphoma. In order to make informed treatment and quality of life decisions, it is important to build a strong knowledge base. Lymphoma Focus Patients and Caregivers will help improve the understanding of lymphoma diseases by presenting the opinions and recommendations of leading lymphoma experts on a broad range of topics.
lymphoma features Selecting a Targeted Therapy in NHL When to Initiate Radioimmunotherapy in NHL
more on lymphoma 2002 Educational Forum 2001 Educational Forum Lymphoma Diagnosis Lymphoma Subtypes ... Sign up for Newsletter Much progress has been made in the study of lymphoma diseases. The medical community continues to advance their understanding of the genetic, environmental and molecular involvement, but more work needs to be done. Lymphoma Focus Professional will present the latest research findings critical to the care and treatment of people with Hodgkins and non-Hodgkins lymphoma. Learn about new diagnostic technologies, therapeutic targets and novel lymphoma agents.
current lymphoma research Altering the Course of Lymphoma Faculty Practical Issues in Radioimmunotherapy for Non-Hodgkin's Lymphoma: Proceedings from a CE Symposium at the ONS 2002 Annual Congress.

14. ELEKTA / Non-Hodgkins Lymphoma
BACK TO THE TOP WHAT HAPPENS AFTER TREATMENT FOR NONHODGKIN'S LYMPHOMA? BACK TOTHE TOP WHAT DOES THE FUTURE HOLD FOR PATIENTS WITH NON-HODGKIN'S LYMPHOMA?
http://www.elekta.com/ContentUS.nsf/va_LookupByWebTitle/non-hodgkins_lymphoma
Content supplied by:

Note:
This website is not intended as a substitute for professional medical advice and does not address specific treatments or conditions specific to any patient. All health and treatment decisions must be made in consultation with your physician(s), utilizing your specific medical information. The information on this website is subject to change. The information provided below has been modified from that furnished by the National Institutes of Health and the National Cancer Institute of the United States of America. WHAT ARE NON-HODGKIN'S LYMPHOMAS?
Lymphoma is a general term for cancers that develop in the lymphatic system. They account for about 4 percent of all cases of cancer in this country.
The most common type of lymphoma is called Hodgkin's disease. All other lymphomas are grouped together and are called non- Hodgkin's lymphomas.
The lymphatic system is part of the body's immune defense system. Its job is to help fight diseases and infection. The lymphatic system includes a network of thin tubes that branch, like blood vessels, into the tissues throughout the body. Lymphatic vessels carry lymph, a colorless, watery fluid that contains infection-fighting cells called lymphocytes. Along this network of vessels are groups of small, bean-shaped organs called lymph nodes that filter the lymph as it passes through the nodes. Clusters of lymph nodes are found in the underarm, groin, neck, and abdomen. Other parts of the lymphatic system are the spleen, thymus, tonsils, and bone marrow. Lymphatic tissue is also found in other parts of the body, including the stomach, intestines, and skin.

15. Love And Lymphoma
The is a tribute site for a brave soul who finally gave up her brave struggle with nonhodgkins lymphoma on October 22, 2000.
http://www.love-and-lymphoma.com
The web page you are looking for can be found at:
http://www.fnwd2.co.uk/landl/index.html

16. Lymphoma Focus - Educational Resources About Hodgkins Disease, Non-hodgkins Lymp
More accurate diagnosis and effective treatments have improved the longtermoutlook for many people with Hodgkins and non-hodgkins lymphoma.
http://www.lymphomafocus.org/
A Comprehensive Educational Resource for the Lymphoma Community Lymphoma strikes men, women and children of all ages. More accurate diagnosis and effective treatments have improved the long-term outlook for many people with Hodgkins and non-Hodgkins lymphoma. In order to make informed treatment and quality of life decisions, it is important to build a strong knowledge base. Lymphoma Focus Patients and Caregivers will help improve the understanding of lymphoma diseases by presenting the opinions and recommendations of leading lymphoma experts on a broad range of topics.
lymphoma features Selecting a Targeted Therapy in NHL When to Initiate Radioimmunotherapy in NHL
more on lymphoma 2002 Educational Forum 2001 Educational Forum Lymphoma Diagnosis Lymphoma Subtypes ... Sign up for Newsletter Much progress has been made in the study of lymphoma diseases. The medical community continues to advance their understanding of the genetic, environmental and molecular involvement, but more work needs to be done. Lymphoma Focus Professional will present the latest research findings critical to the care and treatment of people with Hodgkins and non-Hodgkins lymphoma. Learn about new diagnostic technologies, therapeutic targets and novel lymphoma agents.
current lymphoma research Altering the Course of Lymphoma Faculty Practical Issues in Radioimmunotherapy for Non-Hodgkin's Lymphoma: Proceedings from a CE Symposium at the ONS 2002 Annual Congress.

17. Non-Hodgkin's Lymphoma - Oncologychannel
Resources and information on non-Hodgkin's lymphoma with information about the distingishing of this Category Health Conditions and Diseases Lymphoma Non-Hodgkin s...... Lymphomas are the malignant counterpart of these normal cells. NHLFacts nonhodgkins lymphoma (NHL) is a heterogenous disease.
http://www.oncologychannel.com/nonhodgkins/
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NON-HODGKIN'S
LYMPHOMA
Overview

NHL versus Hodgkin's

Risk Factors

Symptoms
...
Radiation Therapy

CONDITIONS Adrenal Cancer AIDS Related Lymphoma Bladder Cancer Brain Cancer Breast Cancer Carcinoid Malignancy ... Classification of Cancer Colorectal Cancer Cytopenia Endometrial Cancer Esophageal Cancer ... Lymphoma- Hodgkin's Disease Lymphoma- Non-Hodgkin's Melanoma Non-Melanoma Skin Cancer Ovarian Cancer Pain Pancreatic Cancer Prostate Cancer ... Urethral Cancer RESOURCES HealthProfiler Education Links Questions to Ask Your Physician Self Help Videos ABOUT US Healthcommunities.com Pressroom Testimonials Overview Lymphomas are cancers of the lymphatic system - the body's blood-filtering tissues that help to fight infection and disease. Like other cancers, lymphomas, occur when cells divide too much and too fast. Growth control is lost, and the lymphatic cells may overcrowd, invade, and destroy lymphoid tissues and metastasize (spread) to other organs. There are two general types of lymphomas: "Hodgkin's Disease" (named after Dr. Thomas Hodgkin, who first recognized it in 1832) and non-Hodgkin's lymphoma. The lymphatic tissue in Hodgkin's disease contains specific cells - Reed-Sternberg cells - that are not found in any other cancerous lymphomas or cancers. These cells distinguish Hodgkin's disease (HD) from non-Hodgkin's lymphomas (NHLs). Anatomy The lymphatic system - the target of lymphomas - includes the lymph nodes and other organs that make up the immune and blood-forming (hematopoietic) elements of the body.

18. Lymphoma And Leukemia Care - Non-Hodgkin's Lymphoma Treatment Information.
The complete lymphocytic leukemia and non hodgkins lymphoma resource on theweb. nonhodgkins lymphoma Resources Click for Overview on Lymphoma
http://www.llcare.org/nhl/understandingnhl.htm
Lymphoma and Leukemia Care
Non-Hodgkins Lymphoma Leukemia Resources Related Links Related Articles ...
Receive Free Information on Non-Hodgkins Lymphoma
Non-Hodgkins Lymphoma Resources
play > What is Non-Hodgkin's Lymphoma?
Non-Hodgkin's lymphoma is a complex and often confusing group of diseases. Tune in for an expert overview of the biology of NHL, as well as its diagnosis and treatment.
transcript >>

play > NHL: A Survivor's Journey
As a behavioral psychologist, Brian Stabler knew a lot about dealing with emotional stress. But nothing prepared him for the challenge of lymphoma. Tune in to hear how he overcame NHL and the important lessons he learned in the process.
transcript >>

play > How Immunotherapy Works
Traditional cancer therapies like chemotherapy and radiation therapy are notorious for their severe side effects. Newer "immunotherapies," which target cancer cells and leave other cells alone, are more tolerable. But how effective are they? Tune in to learn the latest on this developing treatment strategy.
transcript >>
play > Combining Rituxan and Chemotherapy: What are the Benefits?

19. LookSmart - Non-Hodgkins Lymphoma
Search the Web for. nonhodgkins lymphoma. Find resources on the symptoms,diagnosis and treatment of non-hodgkins lymphoma.
http://www.looksmart.com/eus1/eus302562/eus317837/eus317920/eus53948/eus72007/eu

20. Diffuse, Undifferentiated Non-Hodgkins Lymphoma Among Homosexual Males -- United
Diffuse, Undifferentiated nonhodgkins lymphoma among Homosexual Males United States. A recent outbreak of Kaposi's sarcoma, Pneumocystis
http://www.cdc.gov/mmwr/preview/mmwrhtml/00001104.htm
Diffuse, Undifferentiated Non-Hodgkins Lymphoma among Homosexual Males United States
A recent outbreak of Kaposi's sarcoma, Pneumocystis carinii pneumonia, and other opportunistic infections (KSOI) involving homosexual males and associated with an acquired cellular immunodeficiency syndrome has been described (1,2). While the pathogenesis of these disorders among homosexual males in San Francisco was being studied, 4 cases of diffuse, undifferentiated non-Hodgkins lymphoma (DUNHL) were diagnosed between March 1981 and January 1982. Because of the rarity of this malignancy and the potential relationship of these cases to the KSOI syndrome, they are reported here. Patient 1: A 28-year-old hospital clerk complained of back and shoulder pain starting in early March 1981. Within a few days he had swelling of the right eye and an unsteady gait, and he was hospitalized on March 21. "Shotty" peripheral lymphadenopathy was present. A biopsy of an orbital mass and an enlarged cervical lymph node disclosed DUNHL. A myelogram revealed a T4-T6 block by an extradural mass. Radiation and chemotherapy led to complete remission. In September 1981, another tumor in the spinal cord was treated with radiation. The ensuing remission was temporary, and the patient died with disseminated DUNHL on January 15, 1982. Patient 2: A 33-year-old nurse developed a tumor in his left lower jaw in October 1981. Penicillin was given for a suspected abscess, but the mass enlarged. A biopsy on November 24 disclosed DUNHL. Tumor cells contained surface IgM, kappa type, indicating a B-cell tumor. The tumor involved a left axillary lymph node, the retroperitoneum, the bone marrow, and the meninges. Generalized "reactive" lymphadenopathy and mild splenomegaly were present. Systemic and intrathecal chemotherapy led to temporary tumor regression; the patient relapsed and died in March 1982.

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