81. : The AMEDEO Literature Guide AMEDEO Internet Services Free Journals Free Books. pancreatitis. http://www.amedeo.com/medicine/pan.htm

Home Guestbook FAQ Unsubscribe ... Medicine on Earth AMEDEO Internet Services: Free Journals Free Books Pancreatitis New articles You may choose a subset of the following journals and subscribe to our free E-mail service . Every week you will receive an E-mail with bibliographical details and links to available abstracts . Furthermore, we will assign you a free personal Web page for the one-time downloads of all available abstracts ( see example ). Your personal literature Web page is located on one of our servers and will be updated for you once weekly. For further detailed bibliographic information, we recommend the PubMed site 1. Journals Last update: 03.03.2003 We have pre-selected the journals we recommend to our readers. AJR Am J Roentgenol Am J Gastroenterol Am J Surg Ann Surg ... Transplant Proc 2. E-mail Service Our E-mail service is free of charge. You may select any of the journals listed above, and you will receive every week a list of articles published in your journal subset. To register, fill out the following form and click the "Submit my application." button. At any time you may renew your request choosing another subset of journals.

82. MUSC DDC - Surgeries Visit MUSC Health.com Best viewed using FREE! Microsoft Internet Explorer. PatientInformation. CHRONIC pancreatitis SURGERY. 01. What is Chronic pancreatitis? http://www.ddc.musc.edu/ddc_pub/patientInfo/surgeries/pancreatic/

83. Chronic Pancreatitis Welcome to the Chronic pancreatitis website. Please click on the apples belowto be taken to other pages. pancreatitis Stories. pancreatitis Information. http://www.maraleah.com/ChronicPancreatitis.htm

Welcome to the Chronic Pancreatitis website. Here you will find information and links as well as stories of how others have endured and handled their battle with Chronic Pancreatitis. Please understand that this information is for enlightenment purposes only and you should always be under a doctor's care in treating this disease. Only a doctor can prescribe medications necessary for controlling the pain and other symptoms of this retched illness. This site does not presume to usurp the doctor's role in management of your condition, only supplement your understanding and education about the disease. Please click on the apples below to be taken to other pages. Pancreatitis Stories Pancreatitis Information Pancreatitis Links Members Map Message Board Home Next E-mail Designed by Mary L. Hayden © 2001-2002. copied, uploaded to another server or linked to.

84. Acute Pancreatitis Acute pancreatitis. M Stephen Ledbetter, MD Donald DiSalvo, MD. July24, 1996. Presentation. Diagnosis. Acute pancreatitis. Discussion. http://brighamrad.harvard.edu/Cases/bwh/hcache/187/full.html

Acute Pancreatitis M Stephen Ledbetter, MD Donald DiSalvo, MD July 24, 1996 Presentation A 38-year-old woman presented with severe epigastric pain (radiating to her back), diarrhea, and foul smelling, yellow stools. Serum amylase and lipase were elevated. Imaging Findings Abdominal ultrasonography Sonographic images show pancreatic head enlargement at 5.4 cm ( arrow ), splenic vein edema along the body of the pancreas ( arrow ), and retroperitoneal fluid within the anterior pararenal space ( arrow ). Normal flow was detected in the splenic vein with color doppler and echogenicity of the pancreas was normal. Differential Diagnosis Pancreatic neoplasm Lymphoma Splenic vein thrombosis Posterior duodenal ulcer Pancreatitis Diagnosis Acute pancreatitis Discussion The normal pancreas measures approximately 3 cm at the head, 2 cm at the body, and 1 cm at the tail. In acute pancreatitis, the gland may be enlarged and have decreased echogenicity secondary to edema. In most cases of acute pancreatitis, however, the ultrasound examination is entirely normal. Splenic vein edema has been described as a secondary finding of acute pancreatitis. In chronic pancreatitis, the pancreas is decreased in size secondary to fibrosis, and the echogenicity is increased owing to fatty infiltration. Dystrophic calcifications and ductal dilatation are also hallmarks of chronic pancreatitis. References 1. Jeffrey RB, Laing FC, Wing, VW. Extrapancreatic spread of acute pancreatitis: New observations with real-time US. Radiology 1986; 159: 707-711.

85. Acute Pancreatitis Acute pancreatitis. Faye C Laing, MD. March 28, 1994. Presentation.The patient Diagnosis. Acute pancreatitis. Discussion. These sonographic http://brighamrad.harvard.edu/Cases/bwh/hcache/28/full.html

Acute Pancreatitis Faye C Laing, MD March 28, 1994 Presentation The patient presented with recurrent episodes of midepigastric pain. Imaging Findings Transverse Ultrasound Single transverse image shows that pancreatic echogenicity is within normal limits, but the gland is mildly enlarged. In addition, a complex fluid collection ( arrow ) lies anterior to the pancreas, and abnormal sonolucency ( arrow ) surrounds the splenic vein. Diagnosis Acute pancreatitis Discussion These sonographic findings are due to complications of acute pancreatitis with fluid in the lesser sac and perivascular inflammation surrounding the splenic vein. These vascular changes frequently extend into the superior mesenteric and/or portal veins. Because venous thrombosis may be a sequellae of acute pancreatitis, careful follow-up examinations (with color Doppler) should be done to look for this potential complication. Interestingly, as in this case, some patients with acute pancreatitis show more inflammatory changes outside of the gland than within the substance of the pancreas. Return to the Teaching Case Database search page Return to Professional Education About BrighamRAD Dear Visitors: Nothing on this World Wide Web site should be considered medical advice. Only your own doctor can help you make decisions about your medical care. It is not the policy of the Brigham and Women's Hospital Department of Radiology to provide consultation on the World Wide Web or via e-mail. If you have a specific medical question or are seeking medical care, please call the Brigham and Women's Hospital toll-free physician referral line at 1-800-294-9999.

86. Acute Pancreatitis acute pancreatitis. Findings CXR. elevated hemidiaphragm; atelectasis/ consolidation; pulmonary edema (direct toxic effect? cardiosuppression http://chorus.rad.mcw.edu/doc/00005.html

CHORUS Collaborative Hypertext of Radiology Pancreas Feedback Search acute pancreatitis Findings: CXR elevated hemidiaphragm atelectasis / consolidation pulmonary edema (direct toxic effect? cardiosuppression?) pleural effusion (more common on LEFT) UGI sentinel loops colon cut-off sign antral pad duodenum: widened loop, thickened folds inverted "3" (Frostberg sign) CT normal in ~1/3 hypodensity enlargement standing of mesenteric fat and thickening of anterior perirenal fascia Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 14 March 2001 Medical College of Wisconsin

87. Colloidal Silver Vs. Pancreatitis pancreatitis In cases where an infection is involved, we believe colloidal silvercan be a good treatment though we are not doctors and the FDA has not http://www.utopiasilver.com/testimonials/pancreatitis.htm

If you would like to be kept up to date on the latest information about colloidal silver including personal testimonials of cures by real people and sale prices on our products of up to 30% off, just put your email address here and press subscribe. We call our newsletter "Silver Nuggets". Colloidal Silver vs. Pancreatitis Testimonials of successful treatments - In cases where an infection is involved, we believe colloidal silver can be a good treatment though we are not doctors and the FDA has not approved this treatment. Colloidal silver is very effective at stopping infection. Pancreatitis is an inflammation of the pancreas. The pancreas is a large gland behind the stomach and close to the duodenum. The duodenum is the upper part of the small intestine. The pancreas secretes digestive enzymes into the small intestine through a tube called the pancreatic duct. These enzymes help digest fats, proteins, and carbohydrates in food. The pancreas also releases the hormones insulin and glucagon into the bloodstream. These hormones help the body use the glucose it derives from food for energy. Normally, digestive enzymes do not become active until they reach the small intestine, where they begin digesting food. But if these enzymes become active inside the pancreas, they start "digesting" it.

88. LIMIT Information About Acute Pancreatitis ACUTE pancreatitis YOUR QUESTIONS ANSWERED. How is acute pancreatitis treated?How acute pancreatitis is treated depends on how severe the disease is. http://www.limit.ac.uk/pancreas/acute.htm

Leeds Institute for Minimally Invasive Therapy ACUTE PANCREATITIS: YOUR QUESTIONS ANSWERED Index Introduction What is acute pancreatitis? What are the symptoms of acute pancreatitis? What causes acute pancreatitis? ... Can LIMIT help further? Introduction This leaflet has been designed to introduce you to acute pancreatitis. Its aim is to help you, the patient, learn and understand more about the disease you are suffering from and also to try and help you to cope with the disease itself Top What is acute pancreatitis? It is inflammation of the pancreas and usually develops very suddenly It arises when the pancreas becomes damaged or irritated by its own enzymes, and the body reacts to this damage causing the inflammation It usually requires hospital treatment with the majority of patients improving steadily over the course of a week or so Top What are the symptoms of acute pancreatitis? Pain in the centre of or the top of the abdomen, which may also spread to the back. This usually comes on suddenly and can be very severe General malaise and fevere Nausea and vomiting Some people may have jaundice (yellow skin).

89. LIMIT Chronic Pancreatitis Homepage CHRONIC pancreatitis. What is chronic pancreatitis? Like acute pancreatitis it isalso inflammation of the pancreas. Top. How serious is chronic pancreatitis? http://www.limit.ac.uk/pancreas/chronic.htm

Leeds Institute for Minimally Invasive Therapy CHRONIC PANCREATITIS What is Chronic Pancreatitis? What is Chronic Pancreatitis? How do Acute and Chronic Pancreatitis differ? What happens if my Pancreas becomes damaged? What are the causes? ... Can LIMIT help further? What is chronic pancreatitis? Like acute pancreatitis it is also inflammation of the pancreas. There are however a number of differences between them Top How do ACUTE and CHRONIC Pancreatitis differ? Chronic pancreatitis is different to acute pancreatitis . In acute pancreatitis the episodes of inflammation are usually short and reversible. In chronic pancreatitis there is a mild (usually) continuous inflammation. This inflammation can lead to permanent damage of the pancreas Top What happens if my pancreas becomes damaged? Damage to the pancreas can lead to trouble in the breakdown and digestion of food. If the inflammation worsens, then control of blood glucose can also be lost. This is called diabetes mellitus Top What are the causes?

90. Acute Pancreatitis Acute pancreatitis in Children pancreatitis is an infrequently recognizedcause of abdominal pain in children. CHRONIC pancreatitis. http://home.coqui.net/myrna/pancr.htm

Acute Pancreatitis in Children Pancreatitis is an infrequently recognized cause of abdominal pain in children. The diagnosis sometimes is difficult but the following clinical description may help. ETIOLOGY Drugs/toxins: thiazides, steroids, azathioprine, alcohol, tetracycline, salicylazosulfapyridine, chlorthalidone, furosemide, L-asparaginase, oral contraceptives, organophosphates. Trauma/surgery/child abuse Biliary Tract Disease: choledochal cyst, stricture of the common bile duct, congenital stenosis of the ampulla of Vater, anomalous insertion of the common bile duct, cholelithiasis/cholecystitis. Infection: mumps (even in the absence of parotitis), hepatitis B, coxsackie B5, Epstein-Barr virus, mycoplasma, influenza B. Diabetes mellitus (ketoacidosis) Perforated duodenal ulcer Miscellaneous: hyperparathyroidism, septic shock, cystic fibrosis, pregnancy, acute porphyria, kwashiorkor, hyperproteinemia I and V, scorpion bites. Idiopathic Vasculitis: SLE, Henoch-Schönlein, Kawasaki. Nutritional: malnutrition, rapid feeding, bulimia. SIGNS AND SYMPTOMS 1. Abdominal pain. Children may not localize the pain very well. It is usually noted to be in the upper quadrants or the periumbilical area. The pain is usually constant, but it may be intermittent, and it may be made worse by eating. The knee-chest position will usually relieve the pain.

91. Chronic Pancreatitis Chronic pancreatitis. Reviewed by Dr Alan Ogilvie, consultant physicianand gastroenterologist What is the pancreas? What is pancreatitis? http://www.netdoctor.co.uk/diseases/facts/chronicpancreatitis.htm

The UK's leading independent health website Search NetDoctor NetDoctor.co.uk Home News and features News Newsletter Features Encyclopaedia Diseases Medicines Examinations Health centres Cancer Children's health Depression Erectile dysfunction ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital NetDoctor on call Search Medline ... Text message services Information About NetDoctor Commercial opportunities NetDoctor.com Chronic pancreatitis Reviewed by Dr Alan Ogilvie , consultant physician and gastroenterologist What is the pancreas? The pancreas (A) secretes the enzymes necessary to digest the food, produced by the ductal cells (B), and insulin used for the transport of sugars, made by the islets of Langerhans cells (C), into the blood. The pancreas is a soft, elongated gland situated at the back of the upper abdominal cavity behind the stomach. It is divided into the head (through which the common bile duct runs as it enters the duodenum) and the body (which extends across the spine and the tail), which is close to the left kidney and to the spleen. Because the pancreas lies at the back of the abdominal cavity, diseases of the pancreas may be difficult to diagnose. What does the pancreas do?

92. Acute Pancreatitis Acute pancreatitis. Aetiology. Idiopathic; Preferable to oral or nasogastricfeeding. Complications of acute pancreatitis. Local. Necrosis http://www.surgical-tutor.org.uk/system/abdomen/pancreatitis.htm

Up Abdominal incisions Groin hernias Other hernias ... Mesenteric ischaemia [ Acute pancreatitis ] Pyogenic liver abscess Amoebic liver abscess Hydatid disease Gynecological pain ... Abdominal masses Acute pancreatitis Aetiology Idiopathic Obstruction Choledocolithiasis Ampullary or pancreatic tumours Pancreatic structural anomalies Toxins Alcohol Drugs - salicylates, azathioprine, cimetidine Trauma Accidental Iatrogenic Metabolic abnormalities Infection Vascular anomalies Diagnosis Serum amylase has low sensitivity and specificity 20% cases of pancreatitis have normal serum amylase (particularly alcoholic aetiology) Serum lipase more sensitive Causes of hyperamylasaemia Perforated peptic ulcer Cholecystitis Generalised peritonitis Intestinal obstruction Mesenteric infarction Ruptured AAA Ruptured ectopic pregnancy Prognostic factors 80% of patients have mild pancreatitis with good recovery Mild disease accounts for less than 5% of the mortality form pancreatitis Mortality from pancreatitis due to: Early multiple organ failure Late infected pancreatic necrosis Haemorrhage Associated co-morbidity Aim of prognostic scores is to identify patients with severe pancreatitis Need to have high sensitivity and specificity Ideally should be applicable on admission Ranson's criteria On admission Within 48 hours pO Can not be applied fully for 48 hours Also poor predictor later in the disease 'Single snapshot in a whole feature length film' APACHE II score Multivariate scoring system Measure objective parameter - vital signs and biochemical analysis Account for premorbid state and age

93. Chronic Pancreatitis Chronic pancreatitis. Bibliography. Apte MV, Keogh GW, Wilson J S. Chronic pancreatitiscomplications and management. J Clin Gastroenterol 1999; 29 225240. http://www.surgical-tutor.org.uk/system/abdomen/chronic_pancreatitis.htm

Up Abdominal incisions Groin hernias Other hernias ... Pancreatic cancer [ Chronic pancreatitis ] Colonic polyps Colorectal carcinoma Liver metastases Anal carcinoma ... Abdominal masses Chronic pancreatitis Chronic inflammatory disease of the pancreas Results in irreversible destruction of both the endocrine and exocrine pancreatic tissue Early stages of the disease may be characterised by episodes of acute pancreatitis Pancreas may appear macroscopically normal Late stage of disease is characterised by pancreatic fibrosis and calcification Pancreatic duct dilatation and stricture formation occurs Cysts form within the pancreatic tissue Aetiological factors include Alcohol Tobacco Pancreatic duct strictures Pancreatic trauma Hereditary pancreatitis Tropical pancreatitis Male to female ratio is approximately 4:1 Mean age of onset is approximately 40 years The incidence is increasing Chronic pancreatitis increases the risk of pancreatic carcinoma Clinical features Pain is the principal symptom in most patients Usually epigastric, sub-costal and radiating to the back Pain may be continuous or episodic Often interferes with life and may lead to opiate abuse Weight lost may occur Loss of exocrine function produces malabsorption and steatorrhoea Loss of endocrine function results in diabetes Investigation Serum amylase is often normal Plain abdominal x-ray may show pancreatic calcification CT or MRI is the most useful investigation for imaging the pancreas May confirm pancreatic enlargement, fibrosis and calcification

94. SELECCIONES VETERINARIAS VIRTUAL - PANCREATITIS CANINA. PARTE I Translate this page pancreatitis CANINA. Los animales que tienen accesos repetidos de PA seguidos conperíodos de recuperación se consideran enfermos de pancreatitis crónica. http://www.seleccionesveterinarias.com/articulos/art8_6.htm

SVV - Volumen 8 - Nº 6 PANCREATITIS CANINA. PARTE I Isabel A. Subirós y Rubén A. Taibo Desde el primer modelo animal experimental realizado por Bernard en 1856, gran parte de la bibliografía veterinaria concerniente a la pancreatitis aguda (PA) tradicionalmente estuvo basada en los resultados de numerosos procedimientos de investigación (en una variedad de especies), que a menudo inducían pancreatitis en extremo graves y rápidamente fatales. De este modo, la extrapolación automática de tales datos (junto a las habituales comparaciones con el ser humano) fue dando origen a una serie de mitos sobre sintomatología y patología clínica, que no permitieron el reconocimiento de las inflamaciones pancreáticas leves y moderadas, tal vez más corrientes en la clínica diaria. Sin lugar a dudas, la ultrasonografía, al facilitar el reconocimiento de la patología pancreática, contribuyó en mucho a modificar los conceptos y criterios sobre la PA vigentes en la actualidad. Dentro de este contexto de modificación conceptual, también es justo destacar la información que ha derivado de experimentos (con bases nutricionales) más coincidentes con la enfermedad espontánea. Debido a su extensión, el presente trabajo se ha dividido en tres partes incluyendo: revisión bibliográfica orientada hacia la clínica (Parte I), casuística basada en nuestra experiencia con la identificación sonográfica de la enfermedad (Parte II) y finalmente, opciones terapéuticas y factores pronósticos (Parte III). Dado que la pancreatitis felina posee características particulares, que la diferencian en mucho de la canina, la misma se describe en un artículo por separado.

95. Home Page For Acute And Chronic Pancreatitis The center specializes in surgical treatment of severe acute pancreatitis andchronic pancreatitis. Specialized pancreatitis. WHAT IS pancreatitis. http://www.surgery.usc.edu/divisions/tumor/PancreasDiseases/web pages/PANCREATIT

WHAT IS PANCREATITIS pancreatitis home page acute pancreatitis chronic pancreatitis Acute pancreatitis Acute pancreatitis is a condition that develops when the pancreas is damaged by an inflammation that leads to swelling and sometimes to necrosis (death) of parts of the pancreas. In about 85% of patients, acute pancreatitis is a mild disease and is associated with a rapid recovery within a few days of onset of the illness. In about 15-20% of patients, acute pancreatitis can lead to severe damage of the pancreas associated with the development of pancreatic necrosis (parts of the pancreas becomes dead). Development of pancreatic necrosis often lead to a severe illness associated with an extended hospital stay, multiple surgical procedures and occasionally death in some patients. Patients with severe acute pancreatitis are at risk for developing the following complications: Failure of multiple body organ systems such as the heart, lungs, liver and kidney Pancreatic necrosis (parts of the pancreas becomes dead) Infected pancreatic necrosis (infection of the dead pancreas) Pancreatic abscess Pseudocysts Pancreatic fistula Damage to surrounding organs such as small bowel, colon and duodenum by the inflammation

96. Genesis Health System - Detailed Disease Info - Pancreatitis pancreatitis. Definition. Acute and Chronic pancreatitis. In Harrison'sPrinciples of Internal Medicine, edited by Anthony S. Fauci, et al. http://www.genesishealth.com/micromedex/detaileddisease/00059680.aspx

Facility Information DeWitt Comm Hosp Genesis Medical Ctr Illini Hospital Genesis Health Grp VNA Pancreatitis Definition Pancreatitis is an inflammation of the pancreas, an organ that is important in digestion. Pancreatitis can be acute (beginning suddenly, usually with the patient recovering fully) or chronic (progressing slowly with continued, permanent injury to the pancreas). Description Acute pancreatitis occurs when the pancreas suddenly becomes inflamed but improves. Patients recover fully from the disease, and in almost 90% of cases the symptoms disappear within about a week after treatment. The pancreas returns to its normal architecture and functioning after healing from the illness. After an attack of acute pancreatitis, tissue and cells of the pancreas return to normal. With chronic pancreatitis, damage to the pancreas occurs slowly over time. Symptoms may be persistent or sporadic, but the condition does not disappear and the pancreas is permanently impaired. Pancreatic tissue is damaged, and the tissue and cells function poorly. There are a number of causes of acute pancreatitis. The most common, however, are gallbladder disease and

97. Feline Pancreatitis ~ Pawprints And Purrs When the pancreas becomes inflamed, the disorder is called pancreatitis.It is caution. Feline pancreatitis What is pancreatitis? The http://www.sniksnak.com/cathealth/pancreatitis.html

With no cost to you but a few moments of your time, clicking on the above ad banners anywhere on this site, will help the feral colony Craig and I maintain which we've moved to our own property. ALL REVENUE derived from these ads are for spay/neuter procedures. Thank you for caring! Susie Home of the Bachman Kiddens Read: Any health care links located here are NOT to replace a veterinarian visit; please take your cat to a vet immediately at any sign of odd behavior or any symptoms of illness or injury. Call your vet and describe your cat's symptoms with any of your concerns about the cat's well-being. Your veterinarian may discover changes in your cat's health that you have overlooked. It is always better to err on the side of caution. Feline Pancreatitis What is pancreatitis? The pancreas is a vital organ which is located in the right side of the abdomen. It has two functions: 1) to produce enzymes which help in digestion of food and, 2) to produce hormones, such as insulin. When the pancreas becomes inflamed, the disorder is called pancreatitis. It is a disease process that is seen commonly in the dog and occasionally in the cat. There is no age, sex, or breed predisposition. There are two main forms of acute (sudden onset) pancreatitis: 1) the mild, edematous form and, 2) the more severe, hemorrhagic form. A few cats that recover from an acute episode of pancreatitis may continue to have recurrent bouts of the acute disease. This is termed the chronic form. The associated inflammation allows digestive enzymes to spill into the abdominal cavity; this may result in secondary damage to surrounding organs, such as the liver, bile ducts, gall bladder, and intestines.

98. General Hip Pain Abdominal Pain Hypertension Allergy Hyperthyroid pancreatitis. I was diagnosed with pancreatitis in 1974. Surgeriescorrected immediate problems, but I continued to have severe http://www.taosacu.com/pancreatitis.htm

General Hyperthyroid Abdominal Pain Irritable Bowel Syndrome ... Hypertension Pancreatitis "I ~Monica Friess Main Office: Chung-Hu Tao, L.Ac. 1251 S. Cedar Crest Blvd., Suite #110A, Allentown PA.18103 This site is maintained by Diversity Interactive Inc.

99. University Of Miami School Of Medicine - Glossary - Pancreatitis Diseases and Conditions. pancreatitis. pancreatitis. What is pancreatitis? pancreatitisis a rare disease in which the pancreas becomes inflamed. http://www.med.miami.edu/patients/glossary/art.asp?ArticleKey=439

100. ThirdAge - Adam - Acute Pancreatitis Acute pancreatitis. Definition Acute pancreatitis is an inflammation (irritationand swelling with presence of extra immune cells) of the pancreas. http://www.thirdage.com/health/adam/ency/article/000287.htm

document.write(''); document.write(''); document.write('<'); document.write('/SCRIPT>'); document.write(''); document.write(''); document.write('<'); document.write('/A>'); document.write('<'); document.write('/NOSCRIPT>'); document.write('<'); document.write('/IFRAME>'); Activities Computers Family Tree Health ... Prevention Acute pancreatitis Definition: Acute pancreatitis is an inflammation (irritation and swelling with presence of extra immune cells) of the pancreas. The pancreas is an elongated, tapered gland, located behind the stomach, that secretes digestive enzymes and the hormones insulin and glucagon Causes, incidence, and risk factors: The chief causes of acute pancreatitis in adults are gallstones , other gallbladder (biliary) disease, and alcohol use . Viral infection ( mumps , coxsackie B, mycoplasma pneumonia , and campylobacter), traumatic injury, pancreatic or common bile duct surgical procedures and certain medications (especially estrogens, corticosteroids, thiazide diuretics, and azathioprine) are other causes. The mechanism that causes pancreatitis is not well known. It is thought that enzymes normally secreted by the pancreas in an inactive form become activated inside the pancreas and start to digest the pancreatic tissue. This process is called autodigestion and causes

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