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         Pickwickian Syndrome:     more detail
  1. Gale Encyclopedia of Medicine: Pickwickian syndrome by Kim A. Sharp M.Ln., 2002-01-01
  2. Pickwickian Syndrome: The Challenge of Severe Sleep Apnea.(Statistical Data Included): An article from: MedSurg Nursing by Kathleen Marchiondo, 2000-08-01
  3. Pickwickian Syndrome: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Kim, M.Ln. Sharp, 2006
  4. Pickwickian Manners and Customs by PercyFitzgerald, 2010-10-03
  5. Pickwickian Manners and Customs by Percy Fitzgerald, 2010-08-20
  6. Das Pickwick-Syndrom: Schlafanfalle u. Periodenatmung bei Adiposen (German Edition) by Uwe Henrik Peters, 1976

1. Pickwickian Syndrome, Obesity, Daytime Sleepiness, PCO2, Hypoventilation, Intens
A physician's story of a patient with the syndrome.Category Health Conditions and Diseases pickwickian syndrome...... After that first visit I diagnosed Gloria's problem as typical ofpickwickian syndrome. Like all syndromes, Pickwickian is not a
http://www.mtsinai.org/pulmonary/books/icu/pickwick.html
"We Can't Kill Your Mother" and Other Stories of Intensive Care
by Lawrence Martin, M.D.
Table of Contents

12. Pickwickian
NOTE: "We Can't Kill Your Mother" and Other Stories of Intensive Care can be downloaded in its entirety as an e-book from 1st Books Library ($4.95). The book can also be ordered in trade paperback format for $13.50. For purchasing the e-book or print versions, please go to 1st Books Library and enter part of the book's title or the author in their search engine. Below are the first few paragraphs of PICKWICKIAN. I knew Gloria Fallows for about two years before she was admitted to Intensive Care. I first saw her as an outpatient in 1992 when she was 63. Even then she was enormous 275 pounds, five feet two inches and had trouble breathing. Her chief complaint was "shortness of my breath." "Oh Dr. Martin!" she exclaimed back then. "I can't walk from here to there without struggling." She pointed to a wall of my office about ten feet away. "How long Mrs. Fallows? How long's it been this bad?" "Only the past few months. But it seems to get worse each day."

2. Pickwickian Syndromes
Vanderbilt University discussion of the history of naming the syndrome, the causes, and its progression.
http://www.mc.vanderbilt.edu/peds/pidl/endocr/pickwick.htm

3. Pickwickian Syndrome Resources On The Internet
Search millions of published articles for news on pickwickian syndrome. The eLibrary newspaper and magazine archive
http://www.healthcyclopedia.com/pickwickian_syndrome.html

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See Also: Health: Conditions and Diseases: Cardiovascular Disorders: Heart Disease: Cor Pulmonale Health: Conditions and Diseases: Sleep Disorders: Sleep Apnea Web Links:
Breathing Disorders During Sleep - Signs and symptoms of sleep apnea and Pickwickian syndrome; effects on the heart and other systems; treatment options; therapy and research. Pickwickian - A physician's story of a patient with the syndrome. Pickwickian Syndrome - Neuroweb posting giving information and advice. Pickwickian Syndromes - Vanderbilt University discussion of the history of naming the syndrome, the causes, and its progression.

4. Re: Pickwickian Syndrome
Re pickwickian syndrome. In Reply to pickwickian syndrome posted by Terri GriffithBledsaw on December 27, 1998 at 080314 Channing L. Bete Co,. Inc.
http://www.sleepnet.com/forum5/messages/290.html
Re: Pickwickian Syndrome
Follow Ups Post Followup Diagnostic Dilemmas FAQ Posted by Eric Stephens on January 04, 1999 at 19:00:33: In Reply to: Pickwickian Syndrome posted by Terri Griffith Bledsaw on December 27, 1998 at 08:03:14: Channing L. Bete Co,. Inc. has a great brochure on the subject. It's easy to understand, they're very good about sending out free brochures, and they pride themselves on mailing requests by the next day. Their web site is WWW.channing-bete.com
Phone: 1-800-628-7733
Also try your local sleep lab for info. Good luck.
Follow Ups:

5. BREATHING DISORDERS DURING SLEEP
Signs and symptoms of sleep apnea and pickwickian syndrome; effects on the heart and other systems; treatment options; therapy and research.
http://www.medhelp.org/lib/breadiso.htm
BREATHING DISORDERS DURING SLEEP National Institutes of Health
National Heart, Lung, and Blood Institute "You Can Snore Your Life Away." This sounds more like a joke than a warning. But, in fact, habitual loud snoring is the most common symptom of breathing disorders that occur during sleep. The person who snores not only sleeps restlessly, but also is at risk for serious disorders of the heart and lungs. Snoring can therefore be lifethreatening because it can lead to high blood pressure, irregular heart beats, heart attacks, and sudden death. Normal breathing must continue at all times whether awake or asleep. The act of breathing is an automatic, highly regulated mechanical function of the body. In healthy sleeping individuals, most muscular and neural activities will slow or even shut down but respiration goes on under a neuromuscular "auto pilot." However, if something goes wrong with the auto pilot during sleep, breathing may become erratic and inefficient. Understanding Sleep Sleep is a complex neurological state. Its primary function is rest and restoring the body's energy levels. Repeated interruption of sleep by breathing abnormalities such as cessation of breathing (apnea) or heavy snoring, leads to fragmented sleep and abnormal oxygen and carbon dioxide levels in the blood. Excessive daytime sleepiness and various disorders of the heart, lungs, and the nervous system result.

6. SmartEngine - SmartGuide ( DISEASE : Pickwickian Syndrome )
All about DISEASE pickwickian syndrome from SmartEngine.com Search For . DISEASE pickwickian syndrome. Featured Web Pages
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  • Sleep Apnea Sourcebook - http://www.icongrouponline.com
    "The Official Patient's Sourcebook" on Sleep Apnea. A comprehesive manual for anyone interested in self-directed research on Sleep Apnea.
    Categories (1-1 of 1) Health: Conditions_and_Diseases: Sleep_Disorders: Sleep_Apnea: Pickwickian_Syndrome
    Web Pages
  • Pickwickian Syndromes
    Vanderbilt University discussion of the history of naming the syndrome, the causes, and its progression.
    - http://www.mc.vanderbilt.edu/peds/pidl/endocr/pickwick.htm Health: Conditions and Diseases: Sleep Disorders: Sleep Apnea: Pickwickian Syndrome
  • Pickwickian
    A physician's story of a patient with the syndrome.
    - http://www.mtsinai.org/pulmonary/books/icu/pickwick.html Health: Conditions and Diseases: Sleep Disorders: Sleep Apnea: Pickwickian Syndrome
  • Breathing Disorders During Sleep
    Signs and symptoms of sleep apnea and Pickwickian syndrome; effects on the heart and other systems; treatment options; therapy and research.
    - http://www.medhelp.org/lib/breadiso.htm
  • 7. Pickwickian Syndrome
    pickwickian syndrome. Follow Ups Post Followup DiagnosticDilemmas FAQ He is the typical pickwickian syndrome patient.
    http://www.sleepnet.com/forum5/messages/286.html
    Pickwickian Syndrome
    Follow Ups Post Followup Diagnostic Dilemmas FAQ Posted by Terri Griffith Bledsaw on December 27, 1998 at 08:02:03: Hi, I'm an RN in my last semester of training to become an FNP. This year, I had the unfortunate experience of knowing what it is like to the family member of a patient in CCU. My brother, age 49, was near death and had called me to be with him. He was suffering the effects of years of morbid obesity and I had been aware of the S/Sx of sleep apnea and had tried to get him into a sleep study for years. He is the typical Pickwickian Syndrome patient. I'd like some sources of information to let him read about the syndrome, but it's not easy to locate on the net. Would you have any specific references? In layman's terms, please. He is a very inteligent man, but when it comes to paying attention to what he needs to do to change, it has to be brief, direct and to the point. Thanks.
    Follow Ups:

    8. Pickwickian Syndrome
    . pickwickian syndrome is a complexof symptoms that primarily affect patients with extreme obesity....... pickwickian syndrome. Definition.
    http://www.healthatoz.com/healthatoz/Atoz/ency/pickwickian_syndrome.html
    Encyclopedia Index P Home Encyclopedia Encyclopedia Index P Pickwickian syndrome
    Definition
    A group of symptoms that generally accompany massive obesity Description Pickwickian syndrome is a complex of symptoms that primarily affect patients with extreme obesity. The syndrome is named after a character in a Charles Dickens novel, The Pickwick Papers , who seemed to show some of the traits of this disease. The major health problem that occurs in patients with this disease is sleep apnea . This is caused in part by the excess amounts of fatty tissue surrounding the chest muscles. This excess fat places a strain on the heart, lungs, and diaphragm of the patient, making it difficult to breathe. Causes and symptoms The major cause of Pickwickian syndrome is extreme obesity. This obesity places an excessive load on the pulmonary system. The role of genetics is also being studied. Symptoms of Pickwickian syndrome include excessive daytime sleepiness, shortness of breath due to elevated blood carbon dioxide pressure, disturbed sleep at night, and flushed face. The skin can also have a bluish tint, and the patient may have high blood pressure, an enlarged liver, and an abnormally high red blood cell count. Diagnosis Some tests that can be used to diagnose this condition include echocardiography to determine heart enlargement or pulmonary hypertension . Giving the patient multiple sleep latency tests can help give an objective measurement of daytime sleepiness. Magnetic resonance imaging (MRI), computed tomography (CT) scans, or fiberoptic evaluation of the upper airway may also be used.

    9. DIRECTORY.TERADEX.COM - Health/Fitness/Diseases/Sleep Disorders/Sleep Apnea/Pick
    Sleep Signs and symptoms of sleep apnea and pickwickian syndrome; effects on the heart and other systems; treatment
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    Phototherapy. Physical allergy. Physical examination. Pica. pickwickian syndrome.Piercing and tattoos. Pilates. Pinguecula and pterygium. Pinta. Pituitary dwarfism.
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    11. ELibrary.com - The Mosby Medical Encyclopedia 10-01-1996,
    eLibrary is the subscription based online library for fun or research. Find out more about securing your guaranteed Free 7day trial with your credit card and retrieve 'eLibrary.com - The Mosby Medical Encyclopedia 10-01-1996, 'pickwickian syndrome''
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    12. Pickwickian Syndrome
    . pickwickian syndrome isa complex of symptoms that primarily affect patients with extreme obesity.......MAIN SEARCH INDEX pickwickian syndrome.
    http://www.hendrickhealth.org/healthy/002142.htm
    MAIN SEARCH INDEX
    Pickwickian syndrome
    Definition
    A group of symptoms that generally accompany massive obesity
    Description
    Pickwickian syndrome is a complex of symptoms that primarily affect patients with extreme obesity. The syndrome is named after a character in a Charles Dickens novel, The Pickwick Papers , who seemed to show some of the traits of this disease. The major health problem that occurs in patients with this disease is sleep apnea . This is caused in part by the excess amounts of fatty tissue surrounding the chest muscles. This excess fat places a strain on the heart, lungs, and diaphragm of the patient, making it difficult to breathe.
    Causes and symptoms
    The major cause of Pickwickian syndrome is extreme obesity. This obesity places an excessive load on the pulmonary system. The role of genetics is also being studied. Symptoms of Pickwickian syndrome include excessive daytime sleepiness, shortness of breath due to elevated blood carbon dioxide pressure, disturbed sleep at night, and flushed face. The skin can also have a bluish tint, and the patient may have high blood pressure, an enlarged liver, and an abnormally high red blood cell count.
    Diagnosis
    Some tests that can be used to diagnose this condition include echocardiography to determine heart enlargement or pulmonary hypertension . Giving the patient multiple sleep latency tests can help give an objective measurement of daytime sleepiness. Magnetic resonance imaging (MRI), computed tomography (CT) scans, or fiberoptic evaluation of the upper airway may also be used.

    13. Pickwickian Syndrome
    to your request for more information regarding the "pickwickian syndrome" which your mother is currently suffering with.
    http://neuro-www.mgh.harvard.edu/neurowebforum/NeuromuscularArticles/Pickwickian
    Pickwickian syndrome
    This response submitted by Anne Marie Farnell on 11/19/96. Author's Email: farnelam@muss.mcmaster.ca Hello there, This is a message responding to your request for more information regarding the "pickwickian syndrome" which your mother is currently suffering with. I am a physiotherapy student from Ontario, Canada. I have only recently read some information on this syndrome. Since I am not a medical doctor, I cannot give you the details about the drugs used to treat this disorder. So, I will tell you the little I have learned from my research.
    My understanding is that most frequently this disorder is associated with being overweight (obese). People with this syndrome tend to stop breathing for periods during their sleep and sometimes during the day. As a result of this, they often have less oxygen in their blood. This can be damaging to various internal organs.
    If your mother is overweight it is very important that she try to lose some weight. The research seems to indicate that even losing 15-20kg will dramatically reduce the symptoms these people suffer (help your mother to breath more easily). One way to do this is to begin a walking program to improve fitness levels. Other treatments seem to include: oxygen therapy, the hormone-progesterone and various other medications. Your mother needs to see a doctor who can determine the cause of her pickwickian syndrome in order to find the appropriate treatment.
    I hope this information gave you a start. I wish you the best of luck in your search for more information. I also hope your mother is able to find some medical help.

    14. Index
    Obesity. Obesity. pickwickian syndrome. Obsessive compulsive disorders. Obsessivecompulsivedisorder. Obstetrics. Obstetrical emergencies. Occupational diseases.
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    A B C D ... N O P Q R S ... Z Obesity Obesity Pickwickian syndrome Obsessive compulsive disorders Obsessive-compulsive disorder Obstetrics Obstetrical emergencies Occupational diseases Occupational asthma Occupational therapy Rehabilitation Olfaction disorders Smelling disorders Onychomycosis Onychomycosis Ophthalmic antibiotics Antibiotics, ophthalmic Ophthalmoplegia Ophthalmoplegia Opioids Analgesics, opioid Opportunistic infections AIDS Mycobacterial infections, atypical Oppositional defiant disorder Oppositional defiant disorder Optic atrophy Optic atrophy Optic nerve diseases Papilledema Optic neuritis Optic neuritis Oral candidiasis Candidiasis Oral contraceptives Oral contraceptives Oral hygiene Oral hygiene Tooth decay Oral surgery Root canal treatment Orchitis Orchitis Orthodontics Malocclusion Orthopedic fixation devices Immobilization Orthopedic surgery Orthopedic surgery Orthostatic hypotension Orthostatic hypotension Shy-Drager syndrome Osteitis deformans Paget's disease of bone Osteoarthritis Osteoarthritis Osteochondritis Osteochondroses Osteogenesis imperfecta Osteogenesis imperfecta Osteomalacia Vitamin D deficiency Osteomyelitis Osteomyelitis Osteopathy Osteopathy Osteopetrosis Osteopetroses Osteoporosis Bone density test Hormone replacement therapy Osteoporosis Osteosarcoma Sarcomas Otitis externa Otitis externa Otitis media Otitis media Otorhinolaryngologic tumors Nasal papillomas Otosclerosis Otosclerosis Otoscopy Ear exam with an otoscope Ovarian cancer Oophorectomy Ovarian cancer Ovarian cysts Infertility drugs Ovarian cysts Ovarian diseases Ovarian torsion Ovariectomy

    15. Web Search Results - Excite
    3. Re pickwickian syndrome. Re pickwickian syndrome. In Reply to pickwickian syndrome posted by Terri Griffith
    http://search.excite.com/search.gw?search=Pickwickian+Syndrome

    16. Arch Dermatol -- Page Not Found
    137;508510, April 2001, pickwickian syndrome and Vanishing Finger Pebbles, BrigitteGranel, MD; Jacques Serratrice, MD; Hicham Mohamed, MD; Claude Weiller
    http://archderm.ama-assn.org/issues/v137n4/ffull/dlt0401-7.html
    Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress
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    17. The Ultimate Guide - WebCrawler
    3. Re pickwickian syndrome. Re pickwickian syndrome. In Reply to pickwickian syndrome posted by Terri Griffith
    http://www.webcrawler.com/cgi-bin/WebQuery?searchText=Pickwickian+Syndrome

    18. History Of Clinical Research On The Sleep Apnea Syndrome
    later in the 19th century of other hypersomnolent, obese patients with loud snoring,which came to be called the pickwickian syndrome in reference to Dickens
    http://www.talkaboutsleep.com/Info/KLW/SleepApnea36.htm
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    Abstract #36 Return to "A Doctor's Perspective"
    History of Clinical Research on the Sleep Apnea Syndrome
    Wolfgang Kuhl
    Deutsche Klinik fur Diagnostik, Wiebaden, Deutschland
    Published in Respiration Vol. 64(Supple 1) pp 5-10, 1997
    Summary
    Berger noted changing patterns of EEG activity with changing levels of consciousness, from wakefulness to sleep. Recording of the EEG with other physiological measures, especially eye movements, enabled Dement and Kleitman in 1957 to define different stages of sleep, particularly the recurrent cycling throughout the night of Rapid Eye Movement (REM) sleep, associated with the waking pattern of the EEG but no return of consciousness or responsiveness to the outside environment.
    But clinical research doesn't always require complex technology. In the earliest stages of discovery, just describing a disease well from a clinical standpoint is an important step. Almost a hundred years before Berger, Charles Dickens wrote a vivid description on what later became identified as a stereotypical, severe form of sleep apnea in a character called "Fat Joe" from

    19. Directory Vaionline: Siti_Mondiali/Health/Conditions_and_Diseases/Sleep_Disorder
    Obesity Hypoventilation Syndrome pickwickian syndrome a group of symptoms that can accompany massive obesity.
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    • Breathing Disorders During Sleep - Signs and symptoms of sleep apnea and Pickwickian syndrome; effects on the heart and other systems; treatment options; therapy and research.
    • Obesity Hypoventilation Syndrome - Pickwickian syndrome: a group of symptoms that can accompany massive obesity. Information and links to related disorders.
    • Obstructive Sleep Apnea - History, epidemiology, pathophysiology, and treatment of Pickwickian Syndrome.
    • Pickwickian - A physician's story of a patient with the syndrome.
    • Pickwickian Syndrome - Neuroweb posting giving information and advice.
    • Pickwickian Syndromes - Vanderbilt University discussion of the history of naming the syndrome, the causes, and its progression.
    • Sleep Apneas - Discussion of different sleep apneas, including a history of Pickwickian syndrome.

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    20. Pickwickian Syndrome
    only one click … For Medical Professionals only. pickwickian syndrome,,Print this article, (from the description of the fat boy
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    *For Medical Professionals only, registration required Pickwickian syndrome, (from the description of the fat boy in Dickens' "Pickwick Papers") combination of obesity, somnolence, plethora and oedema. This association of severe obesity with alveolar hypoventilation may cause pulmonary arterial hypertension
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