41. Myositis (Polymyositis Dermatomyositis) Myositis (polymyositis Dermatomyositis). polymyositis involves inflammationof the muscles and can affect many parts of the body. http://www.arthritis.org/conditions/DiseaseCenter/myositis.asp

Welcome! Log In Create Profile advanced search Español ... 51 Ways to Be Good to Your Joints Myositis (Polymyositis Dermatomyositis) If your question is not answered here, please contact one of our information specialists. What Is It? Treatment Options Who Is At Risk? Resources and Suggestions What It It? Myositis (my-OH-sigh-tiss) is a rare disease that involves inflammation that results in damage to muscle fibers and skin. Myositis is a term that describes several illnesses including polymyositis, dermatomyositis and inclusion body myositis. Polymyositis involves inflammation of the muscles and can affect many parts of the body. When inflammation of skin involved it is called dermatomyositis Treatment Options Exercise approved by your doctor Medications: glucocorticoids; immunosuppressants Physical therapy Rest Who Is At Risk? Myositis usually affects adults between the ages of 30 and 60 and children between the ages of 5 and 15. More women than men are affected. Resources and Suggestions Visit Your Arthritis Store to request the free Myositis brochure.

42. Polymyositis - Medical Dictionary Of Popular Medical Terms To Help You Better Un polymyositis A chronic inflammatory disease of muscle that begins when whiteblood cells, the immune cells of inflammation, spontaneously invade muscles http://www.medterms.com/script/main/art.asp?articlekey=4995&rd=1

43. About Dermatomyositis And Polymyositis A General Overview This page contains an overview of dermatomyositis and polymyositis. Dermatomyositisand polymyositis. What causes polymyositis and Dermatomyositis? http://www.webhealth.co.uk/WebHealth_A-Z_of_Health/About_Dermatomyositis_And_Pol

Dermatomyositis and Polymyositis What is Myositis? Myositis is a connective tissue and autoimmune disease. The body's own immune system makes proteins called "antibodies" for protection against viruses, bacteria and other foreign bodies (antigens). In myositis the immune system is unable to tell the difference between antigens and its own cells and tissues. The immune system makes "auto-antibodies" directed against its own cells and tissues. The build up of these "auto-antibodies" in the tissues causes inflammation, pain and muscle damage. The cause of myositis is still unknown. TYPES OF MYOSITIS Polymyositis Dermatomyositis Inclusion Body Myositis Juvenile Dermatomyositis Mixed Connective Tissue MYOSITIS A GUIDE IN UNDERSTANDING THE DISEASES What is Myositis? Polmyositis and Dermatomyositis are related illnesses affecting muscle and connective tissues of the body. Joints may also occasionally be involved. A rarer form of Polymyositis is known as Localised Nodular Myositis. A more serious and rare form of myositis is Inclusion Body Myositis. In Polymyositis, the main problems are weakness and inflammation of the muscles. ('Poly' means many, 'myo' means muscle, 'itis, means inflammation.)

44. Dermatomyositis And Polymyositis Self Help And Support Groups Dermatomyositis and polymyositis Support Group. The Group's Aims To provides support to sufferers and their families; To help give http://www.webhealth.co.uk/Self_Help_and_Support_Groups_R/Dermatomyositis_And_Po

Dermatomyositis and Polymyositis Support Group The Group's Aims : To provides support to sufferers and their families To help give them a better understanding of their illness. To relieve the isolation felt by individuals when a rare illness is diagnosed To guide sufferers in the right direction for treatment To raise awareness of the conditions To raise funds to promote research 146 Newtown Road Woolston Southhampton Tel: 02380 449708 Fax: 02380 396402 Email info@myositis.org.uk Website: www.myositis.org.uk

45. CCHS Clinical Digital Library Dermatomyositis and polymyositis Clinical Resources. Miscellaneous Dermatomyositisand polymyositis Clinical Resources HealthWeb Homepage http://cchs-dl.slis.ua.edu/clinical/rheumatology/autoimmune/dermatomyositis.html

Clinical Resources by Topic: Musculoskeletal Disorders Dermatomyositis and Polymyositis Clinical Resources Emergency Pediatrics Geriatrics Atlases ... Miscellaneous Resources See also: Musculoskeletal Clinical Procedure Resources General Rheumatology Clinical Resources Dermatomyositis and Polymyositis Patient/Family Resources Harrison's Principles of Internal Medicine 15th Ed.-2001: Table of contents Health Sciences Library subscription INFO Chapter 382: Polymyositis, Dermatomyositis, and Inclusion Body Myositis Table of contents Introduction: Access document General Clinical Features Access document Specific Features Access document Associated Clinical Findings Access document Pathogenesis Access document Differential Diagnosis Access document Diagnosis Access document Treatment Access document Prognosis Access document Chapter 58: Immunologically Mediated Skin Diseases: Table of contents Introduction: Access document Diseases with Prominent Cutaneous Features: Access document Dermatomyositis: Access document Chapter 275: Glomerulopathies Associated with Multisystem Diseases: Table of contents Introduction: Access document Immunologically Mediated Multisystem Diseases: Access document Introduction: Access document Polymyositis and Dermatomyositis: Access document Chapter 259: Interstitial Lung Diseases: Table of contents Introduction: Access document Pathogenesis: Access document Introduction: Access document Granulomatous Lung Disease: Access document Inflammation and Fibrosis: Access document Initial Evaluation: Access document Introduction:

46. Polymyositis -- ECureMe.com polymyositis, There is an adult form of polymyositis in those between 4060years old, and a childhood form seen in those between ages 5-15. http://www.ecureme.com/emyhealth/data/Polymyositis.asp

March 31, 2003 Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health Ask The Doctor Lifestyle Counseling Ask by mail My Health Chart ... Hospitals Polymyositis more about Polymyositis Proximal muscle weakness or Neuromyositis Polymyositis is the inflammation (i.e., irritation, pain, swelling, and damage) of the muscles closest or proximal to the trunk of the body (i.e., limb girdles, neck, and pharynx). It is a progressive condition, with periods of relapse (gets worse) and remissions (gets better). There is an adult form of Polymyositis in those between 40-60 years old, and a childhood form seen in those between ages 5-15.

47. University Of Miami School Of Medicine - Glossary - Polymyositis polymyositis. polymyositis Dermatomyositis. What is polymyositis? polymyositisis a disease of muscle featuring inflammation of the muscle fibers. http://www.med.miami.edu/patients/glossary/art.asp?ArticleKey=454

48. Polymyositis polymyositis. Definition polymyositis is an inflammatory muscle diseasecausing weakness and pain. Dermatomyositis is http://www.chclibrary.org/micromed/00061350.html

Main Search Index Definition Description Causes ... Resources Polymyositis Definition Polymyositis is an inflammatory muscle disease causing weakness and pain . Dermatomyositis is identical to polymyositis with the addition of a characteristic skin rash. Description Polymyositis (PM) is an inflammatory disorder in which muscle tissue becomes inflamed and deteriorates, causing weakness and pain. It is one of several types of inflammatory muscle disease, or myopathy. Others include dermatomyositis (DM) and inclusion body myositis. All three types are progressive conditions, usually beginning in adulthood. A fourth type, juvenile dermatomyositis, occurs in children. Although PM and DM can occur at any age, 60% of cases appear between the ages of 30 and 60. Females are affected twice as often as males. Causes The cause of PM and DM is not known, but it is suspected that a variety of factors may play a role in the development of these diseases. PM and DM may be autoimmune diseases, caused by the immune system's attack on the body's own tissue. The reason for this attack is unknown, although some researchers believe that a combination of immune system susceptibility and an environmental trigger may explain at least some cases. Known environmental agents associated with PM and DM include infectious agents such as Toxoplasma Borrella Lyme disease bacterium), and coxsackievirus. Most cases, however, have no obvious triggers (direct causative agents). There may also be a genetic component in the development of PM and DM.

49. Disorder Information - Polymyositis - Dermatomyositis polymyositis / Dermatomyositis. What are polymyositis and dermatomyositis? In polymyositis,the inflammation is found in many muscles, thus the term poly . http://www.mdac.ca/english/disorder-info/disorder-info-13.htm

Polymyositis / Dermatomyositis What are polymyositis and dermatomyositis? Polymyositis and dermatomyositis are disorders involving inflammation of the voluntary muscles. As a result of this inflammation (myositis), muscles undergo degenerative changes, which may lead to severe disability. In polymyositis, the inflammation is found in many muscles, thus the term "poly". It is present over a prolonged period of time. In dermatomyositis the muscle inflammation is usually accompanied by a skin rash, therefore the prefix "dermato". What are the symptoms of each of these disorders? The symptoms of polymyositis and dermatomyositis vary widely from person to person, with respect to severity, rate of progression and complications. Spontaneous remissions may occur, although as a rule, the natural course of the disease is progressive unless effective treatment can be found. It has been suggested that the more acute the onset, the better the prognosis. In dermatomyositis, a reddish rash appears, typically on the face (cheeks and eyelids), elbows, hands, knees and upper chest. The skin changes in appearance, becoming shiny, tight and thin. A person's fingers may become very blue in cold weather. In polymyositis, there is no skin rash.

50. Arthritis Research Campaign | Polymyositis And Dermatomyositis polymyositis means inflammation of the muscles. back to last page. DERMATOMYOSITISAND polymyositis EXPLAINED. polymyositis means inflammation of the muscles. http://www.arc.org.uk/about_arth/booklets/6009/6009.htm

scotland + n. ireland north wales + midlands east + southeast ... south + southwest Introduction Inflammation of the muscles is called myositis myo = muscle, sitis = inflammation). Polymyositis is a condition which affects many muscles ( poly = many), mainly the larger muscles of the body, such as those around the shoulders, hips and thighs. This booklet also deals with dermatomyositis . This is a disease where a particular skin rash occurs ( derm = skin) with muscle inflammation that is similar to polymyositis. This booklet discusses: the nature of these conditions and the importance of getting proper treatment how many people are affected the probable causes of the conditions how doctors diagnose them and the tests used to do this treatments and possible side-effects of drug therapies current research into the conditions. It concludes by answering questions often raised by people who have polymyositis or dermatomyositis, and gives useful addresses for further information. What are the symptoms of polymyositis and dermatomyositis?

51. Muscular Dystrophy Campaign Polymyositis, Dermatomyositis And Sarcoid Myopathy polymyositis and Dermatomyositis. Written by Dr Bryan Lecky MA MD FRCP for theMuscular Dystrophy Campaign. What are polymyositis and dermatomyositis? http://www.muscular-dystrophy.org/information/KeyFacts/polymyo.html

@import "../../css/cssstyle.css"; Receive copies of our quarterly magazine Get your message to over 30,000 readers by advertising in Target MD magazine. Call for details: David N Russell Polymyositis, dermatomyositis and sarcoid myopathy For Polymyositis Annual Specific Condition Review For Dermatomyositis Annual Specific Condition Review June 2002 Written by Dr Bryan Lecky MA MD FRCP for the Muscular Dystrophy Campaign What are polymyositis and dermatomyositis? They are a group of conditions in which there is inflammation of the muscles. Resulting disability is very variable: sometimes weakness is mild but at the other extreme there may be major disability. Generally speaking, polymyositis (PM) and dermatomyositis (DM) respond to treatment. DM occurring in childhood may have important differences and a separate MDC leaflet is available entitled 'Juvenile Dermatomyositis'. Inclusion Body Myositis (IBM) is another important cause of chronic muscle inflammation, mainly in older male subjects and is also dealt with in another MDC leaflet. With very rare exceptions PM and DM are not inherited. Both PM and DM can affect individuals at any age. What are the symptoms?

52. Muscular Dystrophy Campaign Polymyositis Annual Condition Specific Review. polymyositis Annual Condition Specific Review. Please review. polymyositis(PM) is a rare condition, characterised by inflammation of muscle. http://www.muscular-dystrophy.org/information/KeyFacts/polymyo_update.html

@import "../../css/cssstyle.css"; Receive copies of our quarterly magazine Get your message to over 30,000 readers by advertising in Target MD magazine. Call for details: David N Russell Polymyositis Annual Condition Specific Review. September 2001 Please note - there is an updated fact sheet on Polymyositis (PM) and it would be advisable to read it in conjunction with this review. Polymyositis (PM) is a rare condition, characterised by inflammation of muscle. In the majority of cases a faulty immune system is thought to cause the disorder which results in the body attacking its own muscle cells. There are several treatment options available and most individuals with PM respond well to these. Research has centered on establishing well-designed clinical trials to evaluate current treatment protocols and provide scientific evidence that the benefits outweigh the side effects. Background information: Polymyositis (PM) falls within a group of muscle disorders called inflammatory myopathies. The term PM comes from two words, myositis which means inflammation of muscle and poly meaning many i.e. it is characterised by the inflammation of many muscle tissues. Inflammatory myopathies are thought, in the majority of cases, to be autoimmune disorders caused when the body's own immune system becomes faulty and begins to attack its muscle cells, but the exact cause has not been established. When this occurs the body sees its own muscle cells as foreign and produces highly specific molecules called antibodies to target muscle cells and destroy them. This is the same mechanism that operates in healthy individuals when they have an infection, the bacteria or virus is recognised as foreign and the body produces specific antibodies to target the bacteria or viruses and destroy it. It is a rare condition with an annual incidence rate in the region of 1 per 100 000 and appears to show a female predominance of 2:1, especially amongst African-American woman.

53. Polymyositis:Health Topics:UI Health Care polymyositis. polymyositis is a chronic disease characterized by inflammationand by degenerative changes to muscles and skin. This http://www.uihealthcare.com/topics/bonesjointsmuscles/bone3491.html

Health Topics Category Index Health Topics for Bones, Joints and Muscles Bone and Muscle Cancer Department of Orthopaedics ... UI Back Care - UI Health Care's digital library Send comments and questions to staff@uihealthcare.com University of Iowa Polymyositis Polymyositis is a chronic disease characterized by inflammation and by degenerative changes to muscles and skin. This causes weakness and muscle wasting. The disease is seen more frequently in women than in men, and occurs most often between ages 30 and 50. The cause is unknown. Polymyositis can have a sudden or slow onset. A person with polymyositis will typically complain of the following symptoms: weakness in the hips and shoulders swelling and redness in the joints of the hands and ankles cold hands or feet chronic shortness of breath, even at rest problems swallowing and fever, muscle weakness, weight loss, and joint pain may be the first to occur before the other symptoms Medical evaluation may include the following: history and physical exam blood tests biopsy of the involved area to check for inflammation and electromyography, or EMG, which is a test that looks at muscle strength and function

54. Gordon Starkebaum's Position On Polymyositis polymyositis COM 2/3/98 Gordon Starkebaum, MD History Wagner coined the term polymyositis in 1886; Unverricht penned dermatomyositis in 1891. http://www.puget-sound.med.va.gov/clinicians/starkebaum1.asp

Text Only Version Home Search Site Map ... Gordon Starkebaum, MD Physicians David Gruenewald Gordon Starkebaum Polymyositis COM 2/3/98 Gordon Starkebaum, MD History: Wagner coined the term "polymyositis" in 1886; Unverricht penned "dermatomyositis" in 1891. First case of DM associated with cancer described in 1916. Inclusion body myositis described in 1967. Bohan and Peter proposed criteria for dx in 1975. Syndrome Clinical features Polymyositis Proximal muscle weakness, no rash Dermatomyositis Skin rash, Gottron's papules, weakness Inclusion body myositis No rash, proximal and distal weakness Amyopathic dermatomyositis Skin rash, no muscle weakness, fatigue Juvenile dermatomyositis Skin rash, heliotrope rash, soft tissue Ca++

55. TMA: What Is POLYMYOSITIS? polymyositis, polymyositis (POL ee my oe SIE tis). What is polymyositis? polymyositis(PM) is found mostly in people over the age of 20. http://www.myositis.org/about_myositis/polymyositis.htm

HOME CONTACT US INTERNATIONAL About Myositis ... WHAT IS MYOSITIS? > POLYMYOSITIS Polymyositis (POL ee my oe SIE tis) What is polymyositis? What are the signs and symptoms? What tests will the doctor run to see if I have polymyositis? How is it treated? What is polymyositis? What are the signs and symptoms? Polymyositis (PM) is found mostly in people over the age of 20. More women than men have PM. PM is thought to be an autoimmune disease, meaning the body's immune system, which normally fights infections and viruses, does not stop fighting once the infection or virus is gone. The immune system then attacks the body's own normal, healthy tissue through inflammation (IN fluh MAY shun), or swelling. PM does not cause a rash. Muscle weakness usually happens over days, weeks or months. The weakness begins with muscles closest to and within the trunk of the body. Neck, hip, back and shoulder muscles are examples. Some patients also have weakness in muscles farther from the trunk, like hands and fingers. Many PM patients have trouble swallowing, or dysphagia (dis FAY jee yuh). Some patients have trouble breathing and muscle pain. What tests will the doctor run to see if I have polymyositis?

56. The Contact A Family Directory - DERMATOMYOSITIS And POLYMYOSITIS printer friendly, DERMATOMYOSITIS and polymyositis, http://www.cafamily.org.uk/Direct/d21.html

printer friendly DERMATOMYOSITIS and POLYMYOSITIS home more about us in your area conditions information ... how you can help search this site These conditions are manifestations of a very rare auto-immune inflammatory disease of the muscles and skin. The onset of the disease may be sudden but more usually it develops over a period. Lethargy is often the first symptom. The progress of the disease is unpredictable and may include relapses. Inflammation of the muscle and small blood vessels is thought to be due to invasion of the tissues by lymphocytes (white blood cells). The reason for this is not known. Juvenile Dermatomyositis is a condition which can develop in children at any age. It is thought that infection through exposure to certain common viruses may trigger the disease. It is characterised by weakness and possibly muscular wasting accompanied by a skin rash. Very rarely other organs such as lungs may also be affected. Inheritance patterns None Pre-natal diagnosis None Medical text last updated September 2000 by Professor D Scott, Professor of Clinical Rheumatology, Guy's, King's and St Thomas' School of Medicine, London, UK.

57. AAEM - Patient Resources - Polymyositis Patient Resources polymyositis. polymyositis. polymyositis is aninflammatory disorder of muscle. Most commonly it affects adults http://www.aaem.net/aaem/patientInfo/polymyositis.cfm

Patient Resources - Polymyositis Membership Directory Practice Issues / Advocacy Employment/Training Career Center Fellowship Listing EDX Courses Training Links ... List Rental Polymyositis Polymyositis is an inflammatory disorder of muscle. Most commonly it affects adults, and more women are affected than men. Symptoms include muscle pain and weakness. It is an autoimmune (caused by the body’s immune system) disorder whose exact cause is unclear. The treatment includes steroids and other immune system modifying drugs. For More Information: Myositis Association of America - www.myositis.org National Organization for Rare Disorders (NORD) - www.rarediseases.org Muscular Dystrophy Association - www.mdausa.org To Main Patient Resources Page 421 First Avenue SW, Suite 300 East Rochester, MN 55902 Telephone: (507) 288-0100 Fax: (507) 288-1225 E-mail: aaem@aaem.net

58. NINDS Polymyositis Information Page polymyositis information sheet compiled by NINDS, the National Institute of NeurologicalDisorders and Stroke. More about NINDS polymyositis Information Page. http://accessible.ninds.nih.gov/health_and_medical/disorders/polymyos_doc.htm

Disorders - National Institute of Neurological Disorders and Stroke (NINDS) Skip menus Main sections of the NINDS web site Home About NINDS Disorders-you are in this section ... Find People Disorders section pages and search Image Description Science For the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system. Select Topic Disorder Quick Links Alzheimer's Autism Cerebral Palsy Chronic Pain Epilepsy Headache Multiple Sclerosis Parkinson's Stroke Traumatic Brain Injury More about NINDS Polymyositis Information Page Studies with patients Research literature Press release NINDS Search (search help) Contact us My privacy NINDS is part of the National Institutes of Health Contact us Content for this page NINDS Polymyositis Information Page Reviewed 11-19-2001 Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Polymyositis? Is there any treatment? What is the prognosis? What research is being done? ... Related NINDS Publications and Information What is Polymyositis? Polymyositis is an inflammatory muscle disease that causes varying degrees of decreased muscle power. The disease has a gradual onset and generally begins in the second decade of life. Polymyositis rarely affects persons under the age of 18. The most common symptom is muscle weakness, usually affecting those muscles that are closest to the trunk of the body (proximal). Eventually, patients have difficulty rising from a sitting position, climbing stairs, lifting objects, or reaching overhead. In some cases, distal muscles (those not close to the trunk of the body) may also be affected later in the course of the disease. Trouble with swallowing (dysphagia) may occur. Very rarely, the muscles ache and are tender to touch. The disease may be associated with other collagen vascular, autoimmune or infectious disorders

59. HealthlinkUSA Polymyositis Links medical and health related topics. FindWhat. Click here for page1 of polymyositis information from the HealthlinkUSA directory. http://www.healthlinkusa.com/403ent.htm

60. Polymyositis; Treatment, Prevention, Cure polymyositisSearch information from many of the best polymyositis health sites. Clickhere to go to the next page of polymyositis links 1 2 3 4 5 6 7 8 Next http://www.healthlinkusa.com/content/403.html

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