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         Postural Orthostatic Tachycardia Syndrome:     more detail
  1. Postural Orthostatic Tachycardia Syndrome: Dysautonomia, Orthostatic Intolerance, Supine Position,Tachycardia, Cerebral Blood Flow, Orthostatic Hypotension

61. Inappropriate_Sinus_Tachycardia - HeartCenterOnline For Patients: Heart Health E
Some people believe that the syndrome may be closely related to another rare syndromecalled postural orthostatic tachycardia syndrome (POTS), which reflects
http://www.heartcenteronline.com/Inappropriate_Sinus_Tachycardia.html
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Inappropriate Sinus Tachycardia
Edited By Kenneth M. Stein, M.D., FACC Section 1 of 1
The Arrhythmia Center

News, quizzes, related topics and discussion boards What is inappropriate sinus tachycardia?
Inappropriate sinus tachycardia is a condition in which the patient has a normal heart but an unusually fast heart rate, both at rest and in response to physical activity. It is a generally harmless type of arrhythmia (irregular heart rhythm). If the heart rate is persistently and severely elevated, this sustained level of exertion can damage the pumping ability of the heart; however, this is quite rare.
The cause of inappropriate sinus tachycardia is not well understood. Some people believe that the syndrome may be closely related to another rare syndrome called

62. Nuclear Ventriculogram
Definition Vasovagal Syncope Dysautonomic response to upright posture; IncludesOrthostatic Hypotension; postural orthostatic tachycardia syndrome (POTS).
http://www.fpnotebook.com/CV244.htm
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  • Indications CHF assessment Echocardiogram difficult due to body size Advantages Very accurate in assessing Left Ventricular function Disadvantages Assesses Left Ventricular Function only Must be in sinus rhythm
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    63. Tachycardia - Wikipedia
    postural orthostatic tachycardia syndrome (POTS) is a form of tachycardia that occurswith a change in body position (eg, going from laying down to standing up
    http://www.wikipedia.org/wiki/Cardiac_arrhythmia/tachycardia
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    Tachycardia
    (Redirected from Cardiac arrhythmia/tachycardia Tachycardia is the too-rapid beating of the heart. If the heart beats too rapidly it performs inefficiently and blood flow and blood pressure paradoxically are reduced. Postural orthostatic tachycardia syndrome (POTS) is a form of tachycardia that occurs with a change in body position (eg, going from laying down to standing up) and which is generally due to dysautonomia Tachycardia is a general term that is applied in a lot of different contexts. Most generally it means pathologically increased heart rate.
    • Paroxysmal Tachycardia
      • Supraventricular Paroxysmal Tachycardia (SVT) Ventricular Paroxysmal Tachycardia (VT)
        • sustained unsustained
        Tachycardia, as applied in adult medicine, is defined as a heart rate of over 100 beats per minute (BPM).

    64. HealthChannels.com - Cardiology Links
    for MVP Mitral Valve Prolapse Syndrome Research and Support Postural OrthostaticTachycardia postural orthostatic tachycardia syndrome Rheumatic Fever
    http://www.healthchannels.com/cardiology.shtml

    home
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    ... home > cardiology > Conditions Angina Patient Information Angina Pectoris Angina - Facts Arteriosclerosis ... home > cardiology > Cardiology Resources Angioplasty PTCA Home Page cardiology channel Cardiology Page ... home > cardiology > Publications AHA Journals AHA Scientific Statements Cardiology Research Group Genome-Based Resource for Molecular Cardiovascular Medicine ... Practical Approach to the Child with Hypercholesterolemia This page was last modified on: ©1999, 2000, 2001, 2002 Healthcommunities.com. contact the webmaster with any technical issues.

    65. Links On CFIDS, Fibromyalgia, And Related Illnesses
    from Johns Hopkins where the research that found a link between NMH and CFIDS andFMS was found postural orthostatic tachycardia syndrome (POTS) this is an
    http://sickchicks.homestead.com/links2.html
    Sites about Myalgic Encephalomyelitis/ Chronic Fatigue Immune Dysfunction Syndrome, Fibromyalgia, Dysautonomia, Multiple Chemical Sensitivities/ Environmental Illness and related conditions.
    HOME

    Abbreviations: CFIDS - Chronic Fatigue Immune Dysfunction Syndrome ME - Myalgic Encephalomyelitis FMS - Fibromyalgia Syndrome MPS - Myofascial Pain Syndrome MCS - Multiple Chemical Sensitivities EI - Environmental Illness GWS - Gulf War Syndrome POTS - Postural Orthostatic Tachycardia Syndrome (a form of dysautonomia) NMH - Neurally Mediated Hypotension (another form of dysautonomia)
    Organizations on CFIDS/ME:

    Co-Cure
    has a wonderful site with research on CFIDS, FMS, Myofascial Pain, GWS, MCS and more. They have a large email listserv and are home of the Good Doctor's List.
    The National M.E./FM Action Network
    in Canada offers support, advocacy and education
    CINDA - Chronic Immune and Neurological Diseases Associatio
    n does advocacy and education
    RESCIND - Repeal Existing Stereotypes about Chronic Immunological and Neurological Diseases
    , founded by activist Tom Hennessy, is an activist organization and this web site has many valuable links
    The CFIDS Association
    funds research, lobbies Congress to get more research done, provides free information to the public, publishes the CFIDS Chronicle, and sells other informational products

    66. Qango : Health: Diseases And Conditions: P: Postural Orthostatic Tachycardia Syn
    Options Help. Home Health Diseases and Conditions P PosturalOrthostatic tachycardia syndrome, Suggest a Site. Health, etc. If
    http://www.qango.com/dir/Health/Diseases_and_Conditions/P/Postural_Orthostatic_T
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    67. NEJM -- The Neuropathic Postural Tachycardia Syndrome
    Background The postural tachycardia syndrome is a common disorder that is characterizedby chronic orthostatic symptoms and a dramatic increase in heart rate
    http://content.nejm.org/cgi/content/short/343/14/1008
    HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Previous Volume 343:1008-1014 October 5, 2000 Number 14 Next The Neuropathic Postural Tachycardia Syndrome
    Giris Jacob, M.D., D.Sc., Fernando Costa, M.D., John R. Shannon, M.D., Rose Marie Robertson, M.D., Mark Wathen, M.D., Michael Stein, M.D., Italo Biaggioni, M.D., Andy Ertl, Ph.D., Bonnie Black, R.N., and David Robertson, M.D. Table of Contents Full Text of this article PDF of this article Editors' Summaries ... Related Articles in Medline Articles in Medline by Author: Jacob, G. Robertson, D. Medline Citation Neurologic Disease ...
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    ABSTRACT Background The postural tachycardia syndrome is a common disorder that is characterized by chronic orthostatic symptoms and a dramatic increase in heart rate on standing, but that does not involve orthostatic hypotension. Several lines of evidence indicate that this disorder may result from sympathetic denervation of the legs. Methods We measured norepinephrine spillover (the rate of entry of norepinephrine into the venous circulation) in the arms and legs both before and in response to exposure to three stimuli (the cold pressor test, sodium nitroprusside infusion, and tyramine

    68. NEJM -- Orthostatic Intolerance And Tachycardia Associated With Norepinephrine-T
    orthostatic intolerance is a syndrome characterized by lightheadedness, fatigue,altered mentation, and syncope and associated with postural tachycardia and
    http://content.nejm.org/cgi/content/abstract/342/8/541
    HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Previous Volume 342:541-549 February 24, 2000 Number 8 Next Orthostatic Intolerance and Tachycardia Associated with Norepinephrine-Transporter Deficiency
    John R. Shannon, M.D., Nancy L. Flattem, B.S., Jens Jordan, M.D., Giris Jacob, M.D., D.Sc., Bonnie K. Black, B.S.N., Italo Biaggioni, M.D., Randy D. Blakely, Ph.D., and David Robertson, M.D. Table of Contents Full Text of this article PDF of this article Find Similar Articles in the Journal ... Related Articles in Medline Articles in Medline by Author: Shannon, J. R. Robertson, D. Medline Citation Neurologic Disease ...
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    ABSTRACT Background Orthostatic intolerance is a syndrome characterized by lightheadedness, fatigue, altered mentation, and syncope and associated with postural tachycardia and plasma norepinephrine concentrations that are disproportionately high in relation to sympathetic outflow. We tested the hypothesis that impaired functioning of the norepinephrine transporter contributes to the pathophysiologic mechanism of orthostatic intolerance.

    69. Postural Tachycardia Syn (POTS)
    SC AU Schondorf R AU - Suarez GA AU - Fealey RD AU - Camilleri M TI - Comparisonof the postural tachycardia syndrome (POTS) with orthostatic hypotension due
    http://neuro-www.mgh.harvard.edu/neurowebforum/AutonomicArticles/1.15.9710.47PMP
    Postural Tachycardia Syn (POTS)
    This article submitted by Don Ball on 1/15/97.
    Author's Email: balld@vt.edu
    Medline Search 1/15/97 POSTURAL and TACHYCARDIA
    UI - 95265154
    AU - Low PA
    AU - Opfer-Gehrking TL
    AU - Textor SC
    AU - Benarroch EE
    AU - Shen WK
    AU - Schondorf R
    AU - Suarez GA AU - Rummans TA TI - Postural tachycardia syndrome (POTS). RF - REVIEW ARTICLE: 48 REFS. AD - Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA. AB - In orthostatic intolerance, the patient develops symptoms while standing that are relieved when the patient assumes a supine position. Different degrees of orthostatic intolerance exist, but not a system of grading severity. We have developed a system that grades the severity of orthostatic intolerance by the three-pronged criteria of the rapidity of development and the severity of orthostatic symptoms, the ability of the subject to withstand orthostatic stresses, and the degree of interference with daily living. In this article, this system is presented, and one disorder, postural tachycardia syndrome (POTS), is examined

    70. Autonomic Nervous System Disorders Menu
    postural orthostatic tachycardia (2/2/97) 521 AM; Medical Center Experiences (2/1/97 posturaltachycardia syndrome (1/13/97) 534 PM; Mayo clinic experiences (1/9
    http://neuro-www.mgh.harvard.edu/neurowebforum/AutonomicMenu.html
    Autonomic Nervous System Disorders Menu
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    71. Vaso-Vagal Syndrome
    VasoVagal syndrome includes various syncopes,TMJ, nausea, fainting, orthostatichypotension htm 7/5/98 657 PM 5822 postural orthostatic tachycardia.htm 7/5/98
    http://www.clinicalpsychologist.com/clinicalpsychologist/Vaso-Vagal_Syndrome_sei

    Vaso-Vagal Syndrome includes various syncopes,TMJ, nausea, fainting, orthostatic hypotension, insulin metabolism, and sympathetic-parasympathetic tone
    Click Here to Check Out the New
    Online Vaso-Vagal Discussion Forum
    7/5/98 6:57 PM 5410 Causes of sycncope.htm 7/5/98 6:57 PM 6577 7/5/98 6:57 PM 4654 Disopyramide syncope treatment.htm 7/5/98 6:57 PM 5134 7/5/98 6:57 PM 5651 7/5/98 6:57 PM 6222 HrtRt Var Sleep.htm 7/5/98 6:57 PM 7065 7/5/98 6:57 PM 5415 Infnt reg vgl brake.htm 7/5/98 6:57 PM 6841 Insulin related hypotension.htm 7/5/98 6:57 PM 7154 Lit Review.htm 7/5/98 6:57 PM 4886 Micturation syncope.htm 7/5/98 6:57 PM 5456 Near fainting physiology.htm 7/5/98 6:57 PM 5266 Neurally Mediated Syncopes in review.htm 7/5/98 6:57 PM 4768 Neuroregltn of nose and bronchi.htm 7/5/98 6:57 PM 5822 Postural Orthostatic Tachycardia.htm 7/5/98 6:57 PM 5535 7/5/98 6:57 PM 5247 7/5/98 6:57 PM 5203 7/5/98 6:57 PM 6910 Swallowing disorders from impaired inhibitory mechanisms.htm

    72. Orthostatic Intolerance Syndromes
    Vasoregulatory Asthenia. Currently, there are three main categories used to describeOrthostatic Intolerance Conditions postural tachycardia syndrome (POTS).
    http://www.ndrf.org/orthostat.htm
    NDRF
    National Dysautonomia Research Foundation
    1407 W Fourth Street, Suite 160, Red Wing, MN 55066-2108
    Phone: (651) 267-0525 Fax: (651) 267-0524

    Be sure to visit the NDRF Reference Page where you can learn more about the NDRF Patient Handbook, Videos and other reference materials.
    Definitions History Symptoms ... Prognosis
    Definitions
    It is estimated that over 500,000 Americans are afflicted with Orthostatic Intolerance. Despite the enormity of the number, these conditions are among the least understood of the autonomic disorders. Affecting predominately younger individuals, often in those under the age of thirty five, these syndromes affect more women than men. The onset can be sudden, and the impact can be significant on both lifestyle and on the capacity to work. Often, these conditions tend to be misdiagnosed as either a psychiatric or anxiety - related disorders, due to the nature of the symptoms. Standing upright results in a series of reflexive bodily responses, regulated by the Autonomic Nervous System , to compensate for the effect of gravity upon the distribution of blood. These conditions are a result of an inappropriate response to this change in body position.

    73. Background
    people with postural tachycardia syndrome is a dramatic increase in heart rate thatis not associated with a decrease in blood pressure (orthostatic hypotension
    http://www.biology.bc.edu/biology/courses/BI554/new-mpo-stuff/Postural_Tachycard
    Dysfunction of Nerve Transmission in Legs Related to Postural Tachycardia Syndrome due to Dysfunctional Nerves in Legs Why the study was done How the study was done The researchers measured increases in norepinephrine in the venous blood of the arms and legs of 10 patients and 8 normal subjects after stimulating the sympathetic nervous system. What the researchers found Sympathetic denervation in the legs is suggested by the minimal increases in norepinephrine observed in the leg veins of all 10 patients compared with larger increases observed in their arms and in the arms and legs of the normal subjects. The Briefing In Search of the Underlying Cause for Postural Tachycardia Syndrome Postural tachycardia syndrome usually affects young women in their 20s and 30s. According to these authors, however, the nonspecific nature of the symptoms and absence of orthostatic hypotension have led to a lack of recognition of this syndrome among physicians and researchers. The underlying cause of postural tachycardia is unknown. An abnormality in the sympathetic nerves supplying the legs is suggested by earlier research showing that patients with this syndrome have: A tendency for blood to pool in the legs when standing.

    74. FOR PARENTS OF SICK AND WORN-OUT CHILDREN (CFS, CFIDS, NMH, ME,
    Deals with pediatric chronic fatigue syndrome, neurally mediated hypotension, fibromyalgia and other Category Health Conditions and Diseases Youth and Young Adults...... syndrome (CFS); Chronic Fatigue Immune Dysfunction syndrome (CFIDS); Neurally MediatedHypotension (NMH); postural orthostatic tachycardia (POTS); Fibromyalgia (FMS
    http://www.bluecrab.org/health/sickids/sickids.htm

    75. ScienceDaily News Release: Scientists Identify A Cause Of Fainting Syndrome That
    has been called hyperadrenergic orthostatic tachycardia, or postural orthostatictachycardia (POTS anxiety, anemia, or even chronic fatigue syndrome and treat
    http://www.sciencedaily.com/releases/2001/02/010215074346.htm
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    Scientists Identify A Cause Of Fainting Syndrome That Affects Young Women
    New York, New York and Haifa, Israel, February 12, 2001 People who complain of repeated dizzy spells, elevated heartbeat, or fainting after standing up from a lying position will now have their concerns better addressed by doctors. Neuropathic Postural Tachycardial Syndrome (NPTS) affects approximately 500,000 people in the U.S., primarily women between 20 and 45. Dr. Giris Jacob of the Technion-Israel Institute of Technology in Haifa, and Dr. David Robertson of Vanderbilt University in Tennessee, found that NPTS can be caused, in part, by genetic mutations or by disease that can occur after surgery, pregnancy, or an inflammatory illness. Drs. Jacob and Robertson published their findings in The New England Journal of Medicine (October 5, 2000) and Circulation: Journal of the American Heart Association (April 6, 1999; 99: 1706-1712). Dr. Julian Stewart, professor of physiology at New York Medical College, says the researchers have made significant advances in their field.

    76. VUMC Research; Display Faculty
    orthostatic intolerance and the postural tachycardia syndrome Genetic andenvironment pathophysiologies. Eur J Physiol , 441, R48R51, 2000.
    http://medschool.mc.vanderbilt.edu/facultydata/php_files/show_faculty.php?id3=96

    77. Editorial: Orthostatic Intolerance And Chronic Fatigue Syndrome: New Light On An
    are neurally mediated hypotension (NMH) and postural tachycardia syndrome (POTS). Theyconcluded that this orthostatic tachycardia syndrome seemed similar to
    http://www.immunesupport.com/library/showarticle.cfm/ID/3586/T/CFIDS_FM

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    Arthritis Chronic Fatigue ... Weight Loss Free Catalog Advertisement Editorial: Orthostatic Intolerance and Chronic Fatigue Syndrome: New Light On An Old Problem
    ImmuneSupport.com Journal: J Pediatr 2002 Apr;140(4):387-9 Author: Rowe PC. Affiliation: Divsion of Pediatrics and Adolescent Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287. NLM Citation: PMID: 12006948 Chronic fatigue is a prominent symptom in a variety of overlapping syndromes of circulatory dysfunction, the most notable examples of which are neurally mediated hypotension (NMH) and postural tachycardia syndrome (POTS). An early suggestion that such abnormalities were treatable causes of symptoms in what we now call chronic fatigue syndrome (CFS) was made in 1940 by Alexander MacLean and Edgar Allen.1 They described a group of patients who experienced excessive acceleration of the heart and hypotension after moving from the recumbent to the erect posture, usually associated with symptoms of orthostatic exhaustion, blurring of vision, weakness on exercise, and syncopal episodes. McLean and Allen attributed the tachycardia to a reduced venous return to the heart, in part because symptoms and hemodynamic changes could be provoked within 10 seconds by Flack's test, which involved forced expiration into a tube to maintain a mercury column at 40 mm, thereby reducing blood flow into the thorax.1,2

    78. Info31
    This condition may also be called orthostatic syncope (pronounced sinco-pee), neurallymediated hypotension (NMH), postural tachycardia syndrome (POTS), or
    http://iam.homewithgod.com/helenhummel/info31.html

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    For Parents of Sick and Worn-Out Children
    Recipient of  HEALTHY WAY  "Best of the Web" Award and
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    · Chronic Fatigue Syndrome (CFS)
    · Chronic Fatigue Immune Dysfunction Syndrome (CFIDS)
    · Neurally Mediated Hypotension (NMH)
    · Postural Orthostatic Tachycardia (POTS)
    · Fibromyalgia (FMS)
    · Myalgic Encephalomyelitis (ME) · Ehlers-Danlos Syndrome (EDS) · Chiari I Malformation · Cervical Stenosis · Other Conditions causing Debility in Children and Adolescents When your child persistently suffers from pain, fatigue, heat and exercise intolerance, dizziness, nausea, 'cognitive fog,' and other symptoms of Chronic Fatigue and related syndromes, you as a parent have special kinds of problems. This page is devoted to developing and pointing toward help on these problems. Children who have these kinds of problems are often overlooked, thought to be depressed, considered school-avoidant or irresponsible, lazy, lacking ambition or energy, or self-centered. Why Children with CFS Are Often Overlooked explains why this happens. Another reason these problems are often misdiagnosed is "To Find It, You Have to Listen.'

    79. Chronic Fatigue Syndrome
    Recently the syndrome has undergone a renaissance as the postural orthostatic tachycardiasyndrome , acronymically POTS , reported in adults by workers at
    http://www.nymc.edu/fhp/centers/syncope/cfs.htm
    Chronic Orthostatic Intolerance POTS [Circulatory Findings in POTS and CFS]
    Chronic Fatigue Syndrome Defined
    The chronic fatigue syndrome (CFS) has been defined as a distinct clinical entity characterized by chronic, often relapsing, but always debilitating fatigue lasting for at least 6 months and causing impaired overall physical and mental functioning. Recent CDC criteria (1994) have been broadly formulated in order to standardize research in the field resulting in an operating framework which includes cognitive difficulties, pharyngitis, tender lymphadenopathy, muscle pain, joint pain, headache, sleep disturbance or poor sleep, and post-exercise malaise as central features of the illness. Since a precise etiology for the syndrome remains elusive, the diagnosis is largely made by exclusion once specific medical and psychiatric disorders are ruled out. A central imperative, is to determine to as great an extent as possible, whether there are any single or relatively small set of pathophysiologic entities causing the syndrome. goto top
    Varied Pathophysiology Proposed for CFS
    Investigations into the pathophysiology of CFS have remained inconclusive although several possibilities exist. For example, it might be expected that CFS patients could demonstrate striated muscle deficiencies. However, skeletal muscle energetics, structure and histopathology, physiology, and glycolytic activity have been normal and electromyographic results have been inconclusive in these patients. In vivo analyses of muscle energetics are similarly suggestive but not definitive. Cardiac studies have not consistently demonstrated defects in day-to-day cardiac fitness among CFS patients compared to other deconditioned people. Infectious and immune pathology have often been suspected but not conclusively demonstrated as major etiologic factors although studies hint at impaired inflammatory cytokines and cellular immunity.

    80. Chemical Survivors' Foundation: Main Archives/Abstracts
    in patients with postural tachycardia syndrome (PubMed PubMed); Familial orthostatictachycardia due to Impaired postural cerebral hemodynamics in young patients
    http://www.chemical-survivors.com/Main_Archives/Abstracts/more4.html
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