41. EMedicine - Progeria (Werner Syndrome) : Article By Anna Wozniacka, MD, PhD progeria (Werner Syndrome) Otto Werner originally defined Werner syndrome (WS)in 1904 on the basis of sclerodermalike, thin, tight skin and bilateral http://www.emedicine.com/derm/topic697.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Dermatology Pediatric Diseases Progeria (Werner Syndrome) Last Updated: May 1, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: progeria adultorum, progeria of the adult, pangeria, WS, premature aging disorders AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Anna Wozniacka, MD, PhD , Adjunct Lecturer, Department of Dermatology, Medical University of Lodz, Poland Coauthor(s): Camila K Janniger, MD , Chief of Pediatric and Geriatric Dermatology, Clinical Associate Professor, Dermatology and Pediatrics, UMDNJ-New Jersey Medical School Anna Wozniacka, MD, PhD, is a member of the following medical societies: European Academy of Dermatology and Venereology European Society for Dermatological Research , and Polish Association of Dermatology Editor(s): Takuo Tsuji, MD

42. Progeria Sorry, your browser doesn't suppor Java. progeria Among the rarest peoplein the world are those with progeria, or accelerated aging disease. http://www.manbir-online.com/diseases/progeria.htm

Sorry, your browser doesn't suppor Java. Progeria Among the rarest people in the world are those with progeria, or accelerated aging disease. While leaving intelligence intact, progeria ages the body many times faster than normal, leaving teens with frail bodies of people nearing 100 years old. First described by Dr. Jonathan Hutchinson in 1886 and Dr. Hastings Gilford in 1904. Also known as Hutchinson-Gilford Progeria Syndrome is an extremely rare genetic disease . In this disease the aging process of the body accelerates much faster than what it does in normal humans. This process of aging gallops to about seven times the normal rate. Because of this accelerated aging, a child of ten years would have a look of 70 years old. He or she may also have similar respiratory, cardiovascular, and arthritic conditions that a 70-year-old would have. There is no cure for this disease. The exact cause is unknown, but it is believed due to a single abnormal (mutant) gene. Normally for each gene there are two copies, one from each parent. Progeria is considered to be the result of a

43. * JESSE'S * PROGERIA * WEBSITE * * JESSE'S * progeria * WEBSITE *. progeria progeria, pronounced proh JIHR eeuh, is an extremely rare disorder that causes premature aging in children. http://www.expage.com/progeria9

* JESSE'S * PROGERIA * WEBSITE * Progeria Progeria, pronounced proh JIHR ee uh, is an extremely rare disorder that causes premature aging in children. The disease is also called Hutchinson-Gilford syndrome. It was first described in 1886 by Sir Jonathan Hutchinson, an English physician. Since then, only about 100 cases of progeria have been reported worldwide. The disease occurs only once in every 4 million births. The word progeria comes from a Greek word that means prematurely old. Most people with progeria appear normal at birth, but they soon begin to grow more slowly than normal. By 1 or 2 years of age, their hair turns lighter in color and starts to fall out. By age 3 or 4, they are almost bald. In addition, their skin becomes thin, wrinkled, and spotted, their bodies take on a stooped appearance, and their facial features look "pinched." Their heads appear unusually large and veiny. Many people with progeria develop disorders of the circulatory system, especially high blood pressure, heart disease, and stroke. Some victims die as early as 7 years of age. About half die by age 13. The oldest known person with progeria lived 27 years. The disease does not affect a person's mental development. Many people with progeria are highly intelligent. Most victims are very shy because of their physical appearance. Although people who have progeria continue to grow slowly, few reach a height of 3 feet 6 inches (107 centimeters) or a weight of 40 pounds (18 kilograms).

44. NIH Guide: INNOVATION GRANTS FOR RESEARCH ON HUTCHINSON-GILFORD PROGERIA SYNDROM INNOVATION GRANTS FOR RESEARCH ON HUTCHINSONGILFORD progeria SYNDROME RELEASEDATE April 10, 2002 PA NUMBER PAR-02-097 EXPIRATION DATE April 1, 2005 http://grants1.nih.gov/grants/guide/pa-files/PAR-02-097.html

INNOVATION GRANTS FOR RESEARCH ON HUTCHINSON-GILFORD PROGERIA SYNDROME RELEASE DATE: April 10, 2002 PA NUMBER: PAR-02-097 EXPIRATION DATE: April 1, 2005, unless reissued National Institute on Aging (NIA) ( http://www.nia.nih.gov/ ) National Heart, Lung and Blood Institute (NHLBI) ( http://www.nhlbi.nih.gov/index.htm ) National Institute of Dental and Craniofacial Research (NIDCR) ( http://www.nidr.nih.gov/ ) National Institute of Child Health and Human Development (NICHD) ( http://www.nichd.nih.gov/ http://locus.umdnj.edu/nia , and from The Progeria Research Foundation ( www.progeriaresearch.org http://grants.nih.gov/grants/funding/modular/modular.htm warnerh@nia.nih.gov Dr. Stephen Goldman Vascular Biology Research Program Division of Heart and Vascular Disease National Heart, Lung and Blood Institute 6701 Rockledge Drive, Suite 10193, MSC 7956 Bethesda, MD 20892 – 7956 Carrier Zip 20814 Telephone: (301) 435-0565 FAX: (301) 480-2858 Email: goldmans@nhlbi.nih.gov Dr. Rochelle Small, Director Developmental Biology and Mammalian Genetic Program National Institute of Dental and Craniofacial Research Building 45, Room 4AN-18D Bethesda, MD 20892-6402 Telephone: (301) 594-9898 FAX: (301) 480-8318 Email: rochelle.small@nih.gov

45. 1Up Health Progeria Causes, Incidence, And Risk Factors Of Comprehesive information on progeria (HutchinsonGilford syndrome). 1Up Health Diseases Conditions progeria Causes, Incidence, and Risk Factors. http://www.1uphealth.com/health/progeria_info.html

46. 1UpHealth Health Links Directory Conditions And Diseases Sites. HutchinsonGilford progeria Syndrome (HGPS) Resource Page Providesan overview of the disease as well as links to resources. http://www.1uphealth.com/links/rare-disorders-progeria.html

47. Catalogue For Philanthropy: The Progeria Research Foundation progeriaresearch.org. The progeria Research Foundation, Give What You Think.. Give now to The progeria Research Foundation Catalogue Home http://www.catalogueforphilanthropy.org/cfp/2002/progeria_research_642.htm

Massachusetts 2002 Charities Resources About Us Contact/Apply ... Search Search Human Services : Health and Aging The Progeria Research Foundation Audrey Gordon PO Box 3453 Peabody, MA progeria@netzeo.net www.progeriaresearch.org The Progeria Research Foundation Tell Us What You Think

48. SciZone - Ontario Science Centre: Progeria: Aging Too Fast e3 progeria aging too fast. progeria 'prematurely old'. Both Backto top What's HutchinsonGilford progeria Syndrome? Hutchinson http://www.ontariosciencecentre.ca/scizone/e3/aging/progeria.asp

MM_preloadImages('/scizone/assets/navigation/games_roll.en.jpg','/scizone/assets/navigation/homelab_roll.en.jpg','/scizone/assets/navigation/question_roll.en.jpg','/scizone/assets/navigation/brainz_roll.en.jpg','/scizone/assets/navigation/e3graphic_roll.en.jpg','') Progeria: aging too fast Progeria: 'prematurely old' What's Werner's Syndrome? What's Hutchinson-Gilford Progeria Syndrome? Why does it happen? ... Is there a cure? Progeria: 'prematurely old' Both Werner's Syndrome and HGPS are examples of progeria, which means 'prematurely old.' Progeria isn't exactly rapid aging; people with progeria just look and perhaps feel like they're quickly growing old. Back to top What's Werner's Syndrome? Werner's Syndrome is a rare illness that appears to age the sufferer at twice the normal rate. Those who suffer from Werner's Syndrome show full symptoms in their twenties, and die usually in their thirties or forties, gray-haired and wizened, with multiple conditions such as cancer, heart disease, and osteoporosis. Back to top What's Hutchinson-Gilford Progeria Syndrome?

49. Progeria Edit this Page (locked) Attachments to this Page History of this PageHome Recent Changes Search the Swiki Help Guide progeria. progeria. http://pbl.cc.gatech.edu/mindy/961

Progeria PROGERIA Discovery and History Signs, Symptoms and Diagnosis Anatomical Parts Affected Prevention Options and Occurence ... Links to References Link to this Page Fall 2002 HPS/BIOL 3751 Project topics last edited on 5 December 2002 at 12:36:17 pm by bh107-02.che.gatech.edu

50. History Of Progeria History of progeria. This Version, Name, User, Date, Time. current,progeria, r59h11.res.gatech.edu, 5 December 2002, 60532 pm. progeria, http://pbl.cc.gatech.edu/mindy/961.history

History of Progeria This document contains a history of this page, from the current version to the earliest one available. Version Name User Date Time current Progeria r59h11.res.gatech.edu 5 December 2002 6:05:32 pm Progeria r59h11.res.gatech.edu 5 December 2002 4:15:48 pm Progeria r59h11.res.gatech.edu 5 December 2002 4:15:37 pm Progeria r59h11.res.gatech.edu 5 December 2002 4:15:21 pm Progeria r59h11.res.gatech.edu 5 December 2002 4:12:47 pm center!!Progeria/center r59h11.res.gatech.edu 5 December 2002 4:12:28 pm Progeria r59h11.res.gatech.edu 5 December 2002 4:11:46 pm Progeria r59h11.res.gatech.edu 3 December 2002 11:12:30 pm Progeria r59h11.res.gatech.edu 3 December 2002 11:11:25 pm Progeria dhcp61-198.mgt.gatech.edu 3 December 2002 7:58:06 pm Progeria dhcp61-198.mgt.gatech.edu 3 December 2002 7:08:31 pm Progeria dhcp61-198.mgt.gatech.edu 3 December 2002 6:16:54 pm Progeria dhcp61-198.mgt.gatech.edu 3 December 2002 6:08:09 pm Progeria dhcp61-198.mgt.gatech.edu 3 December 2002 6:07:38 pm Progeria dhcp61-76.mgt.gatech.edu 2 December 2002 3:25:14 pm Progeria dhcp61-76.mgt.gatech.edu

51. Edpage.html Welcome to My Web Page on progeria! I discovered my love for children with progeriaone night while watching the Discovery Channel. What is progeria? http://www.geneseo.edu/~mab5/edpage.html

Welcome to My Web Page on Progeria! I discovered my love for children with Progeria one night while watching the Discovery Channel. There was a special on children with Progeria, starring AshleyHegi and her mother Lori. It is a wonderful story of a child with a big heart, big smile, and lots of love to give, who has Progeria. What is Progeria? Progeria, also known as Hutchinson-Gilford Progeria Syndrome, is a rare disease that causes children to age seven times faster than they are supposed to age. It was first discovered in 1886. Currently, there are only 36 children in the world with Progeria. These children go through their lives with serious defects, such as dwarfism, premature aging, and congestive heart failure. According to research that has been completed on this rare disease, the lifespan for children with Progeria ranges from 7 to 27.5 years. The average child with Progeria lives for 13 years. What are the physical signs? children are normal at birth growth stops at the end of the first year possibly a slow increase to the size of a 2 or 3 year old during their first decade total height possibility never exceeding the size of a 5 year old child dwarfism with premature senility relatively large head with a small face beaked nose receding chin prominent eyes cloudiness of cornea absence of eyebrows and lashes crowded, irregular teeth

52. Malady Of The Month Archives The name progeria stems from the Latin and Greek words pro and geraiosand means literally, 'early old age'. progeria is extremely rare. http://asylumeclectica.com/malady/archives/progeria.htm

Precocious senility of striking degree is characteristic of this exceedingly rare disorder. The name progeria stems from the Latin and Greek words pro and geraios and means literally, 'early old age'. The disease is also known as the Hutchinson-Gilford syndrome, after the physicians who first described it, Hutchinson in 1886 and Gilford in 1904. Children with progeria age about ten times faster than normal. This means that these children develop the symptoms of other diseases, which normally occur only in people in their seventies or eighties, at the early age of ten or twelve years. Children with progeria bear a remarkable resemblance to each other both regarding their outward appearance and their symptoms. Their mental development and intelligence is entirely normal and appropriate for their calendar age. At school they are able to perform quite well and thanks to their open and cheerful nature are readily accepted by their schoolmates. However, due to their unusual appearance, they are frequently stared at by strangers and must therefore learn to cope with this from an early age. Their witty reactions to unthoughtful remarks are well-documented. When Jason, a boy with progeria was asked, "When are you going to die?", he retorted: "When are you going to?".

53. Progeria only. progeria,, Print this article, a progeria, Fig. 1 a. AP radiographof the chest demonstrates hypoplasia of the clavicles. b. AP http://www.amershamhealth.com/medcyclopaedia/Volume III 1/progeria.html

Medcyclopaedia About Medcyclopaedia Amersham Health Search for: Type a word or a phrase. All forms of the word are searchable. Advanced search Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search *For Medical Professionals only, registration required Progeria, a congenital disorder characterized by striking premature senility, with many children dying of coronary artery disease before the age of 10 years. Among the manifestations of this disease are dwarfism , brown pigmentation of the trunk, loss of subcutaneous fat, receding chin, and exophthalmos. On radiographs hypoplasia of facial bones and mandible, acro osteolysis of terminal phalanges and of the clavicle, delayed closure of cranial sutures and coxa valga may be evident ( Fig.1 DR/RB The Encyclopaedia of Medical Imaging Volume III:1 Progeria, Fig. 1 a. AP radiograph of the chest demonstrates hypoplasia of the clavicles. b. AP radiograph of the pelvis demonstrates bilateral hip dysplasia and coxa valga. (Courtesy of Brian Howard, MD, Charlotte, NC) Welcome to Medcyclopaedia.

54. Health Information Resource Database: Progeria Research Foundation, Inc. progeria Research Foundation, Inc. Contact Information. Information PO Box 3453Peabody, MA 019613453. Abstract. The progeria Research Foundation, Inc. http://www.health.gov/nhic/NHICScripts/Entry.cfm?HRCode=HR2078

55. Cool Running :: Progeria RAce For Research Race Results Complete 2002 race results for progeria RAce for Research provided by CoolRunning, the complete online resource for runners. progeria overall. http://www.coolrunning.com/results/02/ma/Sep28_Proger_set1.shtml

Massachusetts Event Spotlights Find Events Find Results Race Directors ... Entry forms Download the entry form for your next race. Race directors: Promote your event Discover how Cool Running can help you. Add to our calendar Submit a new race to the event calendar. Submit race results Add race results to our results listings. home races/results find results massachusetts 2002 race results ... Progeria Age Group Progeria overall 1st Annual Progeria Race for Research 5 KILOMETER ROAD RACE Peabody, MA Sept. 28, 2002 Timing by North Shore Striders Place Name Age Sex City State Time Pace JOHN AYERS M JASON BARNES M MIKE DIMAURO M JOE ROCHA M RICH TABBUT M SCOTT ROCHEVILLE M SCOTT OLIVOLO M PEABODY MA DEAN MCNABB M KATHY BURLEY F ANDREW OBER M BOXFORD MA MATHEW REEVES M MICHELE ROY F DINA WILKINSON F LYNNFIELD MA BILLY SHEA M TOM LEAHY M JACQUELINE REGAN F NANCY MILEWSKA F MICHAEL VONZWECK M BEVERLY MA MELISSA SHEA F PETER VONZWECK M ST MA STEPHEN MC AVOY M JOE WIONCEK M BEVERLY MA BRIAN GARDNER M DAVID SMELSER M WENDY BURBANK F BOXFORD MA PHILLIP RAZNEY M PEABODY MA NICK DEBENEDICTIS M BOXFORD MA DAVID REYNOLDS M JILLIAN WIONCEK F BEVERLY MA JOHN CRAGAN M CARLA DROPO F EDWARD GREENBERG M BILL BINGHAM M LARRY HYDE M BOB CONLON M CYNTHIA BENNETT F BOB KATZ M ANDOVER MA DAVID AJEMIAN M JOANNE FORTUNATO F STEVE BENNETT M CAROLYN OSBAHR F GAIL SULLIVAN F STEVEN MCSTAY M JODI MITCHELL F SALEM MA HENRY SACCO M PETER MIGLIACCIO M TOPSFIELD MA LUCA PARATORE M JIM SEARS M TARA KELLY F PEABODY MA VANGIE EGIZI F BEVERLY MA 1st Annual Progeria Race for Research 5 KILOMETER ROAD RACE Peabody, MA Sept. 28, 2002

56. Progeria I think progeria is a fascinating disease. This is my writtenin-two-hoursresearch paper on progeria for my gen/emb course. The http://members.tripod.com/~crunchyfrog/writing/progeria.html

I think progeria is a fascinating disease. This is my written-in-two-hours research paper on progeria for my gen/emb course. The 'Online Resources' part was not explicitly part of the paper, but I used it in my half-assed research process. Debra Horng Genetics and Embryology, 6.0 19 March 1999 Progeria Progeria occurs in approximately one in 8 million children (Klimko B-1). As of June 1998, there are thirty-one people in the world with the disorder (Samolinski 1). Although it is a relatively rare disease, its effects are drastic. The Sunshine Foundation sponsors an annual reunion for families of children with progeria to congregate in Lake Wales, FL (Klimko B-1). Works Cited Wynbrandt, James and Mark D. Ludman. The Encyclopedia of Genetic Disorders and Birth Defects . New York: Facts on File, 1991. 257. Online Resources Sunshine Foundation Miningco: Genetics HGPS Resource Page The End. index email

57. Progeria Back Home Next. progeria HutchinsonGilford progeria Syndrome (HGPS) ResourcePage. progeria Discussion Area. progeria Research Foundation, Inc. http://www.ability.org.uk/Progeria.html

"see the ability, not the disability" You to can help support the Ability Project by: Our Aims ... Z Progeria Hutchinson-Gilford Progeria Syndrome (HGPS) Resource Page Progeria Discussion Area Progeria Research Foundation, Inc. Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

58. Roche Lexikon Medizin (4. Aufl.) - Progeria, Progerie http://www.gesundheit.de/roche/ro30000/r31509.html

Pro geria, Pro gerie engl.: progeria vorzeitige Vergreisung. P. infantum, H UTCHINSON *-G ILFORD * Syndrom, greisenhafter Zwergwuchs engl.: infantile p. OTTRON P. adultorum engl.: Werner's syndrome; adult p. das W ERNER Verwandte Themen Gerodermia, Gerodermie Gilford* Syndrom greisenhafter Zwergwuchs Hautatrophie ... Zwergwuchs

59. Progeria progeria. Definition progeria is a disease that produces rapid aging startingin childhood. Alternative Names HutchinsonGilford syndrome. http://www.pennhealth.com/ency/article/001657.htm

Disease Injury Nutrition Poison ... Prevention Progeria Definition: Progeria is a disease that produces rapid aging starting in childhood. Alternative Names: Hutchinson-Gilford syndrome Causes, incidence, and risk factors: The exact cause of progeria is unknown, although a hereditary component may be involved. Progeria is a rare condition but has come into public awareness because its symptoms strongly resemble normal human aging as well as the appearance of several affected children in movies on national television. Progeria results in rapid aging of children, beginning with growth failure during the first year of life that results in disproportionately small bodies given the size of their heads. The children are thin with baldness , wizened narrow faces, and old-appearing skin. Children with progeria develop early atherosclerosis. The average lifespan is the early teens, some patients live up to 30 but lifespan is shortened. The cause of death is usually related to the heart or a stroke as a result of the progressive atherosclerosis.

60. EMF Awards At Progeria Research Foundation, Inc. Awards at progeria Research Foundation, Inc. Audrey Gordon, Esq. HutchinsonGilfordprogeria Syndrome Workshop. For further information http://www.ellison-med-fn.org/emf_inst.jsp?institution_id=95

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