61. 1Up Health > Health Links Directory > Conditions And Diseases: Genetic Disorders MyLifePath An in depth look at pseudoxanthoma elasticum. NORD pseudoxanthoma elasticumOffers alternative names, a general discussion and resources for PXE. http://www.1uphealth.com/links/genetic-disorders-pseudoxanthoma-elasticum.html

Home Contact Us Privacy Caring For Your Well Being Alternative Medicine Clinical Trials Health News Poisons ... Health Topics A-Z Search 1Up Health Health Directory Addictions Alternative Animal ... Weight Loss By Demography Child Health Teen Health Men's Health Women's Health ... Genetic Disorders : Pseudoxanthoma Elasticum Description See Related Categories Health: Conditions and Diseases: Cardiovascular Disorders: Vascular Disorders Health: Conditions and Diseases: Musculoskeletal Disorders: Connective Tissue Health: Conditions and Diseases: Rare Disorders Sites MyLifePath An in depth look at Pseudoxanthoma elasticum. NORD - Pseudoxanthoma Elasticum Offers alternative names, a general discussion and resources for PXE. PXE International The comprehensive source for pseudoxanthoma elasticum research and world wide activities. VhiHealth-e A definition of Pseudoxanthoma elasticum followed by a description, causes and symptoms, diagnosis, treatment options, prognosis and prevention. Help build the largest human-edited directory on the web.

62. David R. Hardten, MD - Eye Conditions - Pseudoxanthoma Elasticum David R. Hardten, MD. Home Conditions pseudoxanthoma elasticum, http://drhardten.eyemdlink.com/Condition.asp?ConditionID=368

63. Health Library - Pseudoxanthoma Elasticum (PXE) pseudoxanthoma elasticum (PXE). pseudoxanthoma elasticum, PXE, is an inheriteddisorder that affects selected connective tissue in some parts of the body. http://www.laurushealth.com/library/healthguide/illnessconditions/topic.asp?hwid

64. Marguerite McDonald, MD - Eye Conditions - Pseudoxanthoma Marguerite McDonald, MD. Home Conditions pseudoxanthoma elasticum, http://drmcdonald.eyemdlink.com/Condition.asp?ConditionID=368

65. Pseudoxan pseudoxanthoma elasticum (PXE). For further information contact PseudoxanthomaElasticum Support Group (PiXiE), 15 Mead Close, Marlow, Bucks. SL7 1HR. Reg. http://www.skincarecampaign.org/directory/pseudoxan.htm

66. Searchalot Directory For Pseudoxanthoma Elasticum Related Web Sites. PXE International The comprehensive source forpseudoxanthoma elasticum research and world wide activities. http://www.searchalot.com/Top/Health/ConditionsandDiseases/GeneticDisorders/Pseu

Home Search News Email Greetings Weather ... Global All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo! Yahoo! Auctions Yahoo! News Yahooligans Zeal Sponsored Links Top Health Conditions and Diseases Genetic Disorders : Pseudoxanthoma Elasticum Related Web Sites PXE International - The comprehensive source for pseudoxanthoma elasticum research and world wide activities. NORD - Pseudoxanthoma Elasticum - Offers alternative names, a general discussion and resources for PXE. VhiHealth-e - A definition of Pseudoxanthoma elasticum followed by a description, causes and symptoms, diagnosis, treatment options, prognosis and prevention. MyLifePath - An in depth look at Pseudoxanthoma elasticum. Related Categories Health: Conditions and Diseases: Cardiovascular Disorders: Vascular Disorders Health: Conditions and Diseases: Musculoskeletal Disorders: Connective Tissue Health: Conditions and Diseases: Rare Disorders All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index

67. Pseudoxanthoma Elasticum | Ahealthyme.com You are here Home Health A to Z pseudoxanthoma elasticum. PseudoxanthomaElasticum. Organizations National Association for pseudoxanthoma elasticum. http://www.ahealthyme.com/topic/topic100587360

Search AHealthyMe! Personalize AHealthyMe! Sign up for our Newsletter! You are here: Home Health A to Z Pseudoxanthoma Elasticum Lica, Lorraine Below: Definition Description Causes and symptoms Diagnosis ... Resources Definition Pseudoxanthoma elascticum (PXE) is an inherited connective tissue disorder in which the elastic fibers present in the skin, eyes, and cardiovascular system gradually become calcified and inelastic. Description The course of PXE varies greatly between individuals. Typically it is first noticed during adolescence as yellow-orange bumps on the side of the neck. Similar bumps may appear at other places where the skin bends a lot, like the backs of the knees and the insides of the elbows. The skin in these areas tends to get thick, leathery, inelastic, and acquire extra folds. These skin problems have no serious consequences, and for some people, the disease progresses no further. Bruch's membrane, a layer of elastic fibers in front of the retina, becomes calcified in some people with PXE. Calcification causes cracks in Bruch's membrane, which can be seen through an ophthalmoscope as red, brown, or gray streaks called angioid streaks. The cracks can eventually (e.g., in 10-20 years) cause bleeding, and the usual resultant scarring leads to central vision deterioration. However, peripheral vision is unaffected. Arterial walls and heart valves contain elastic fibers that can become calcified. This leads to a greater susceptibility to the conditions that are associated with hardening of the arteries in the normal aging population-high blood pressure, heart attack, stroke, and arterial obstruction-and, similarly, mitral valve prolapse. Heart disease and hypertension associated with PXE have been reported in children as young as four to 13 years of age. Although often appearing at a younger age, the overall incidence of these conditions is only slightly higher for people with PXE than it is in the general population.

68. Peter Sneed, MD - Eye Conditions - Pseudoxanthoma Elasticum Peter Sneed, MD. Home Conditions pseudoxanthoma elasticum, http://psneed.eyemdlink.com/Condition.asp?ConditionID=368

69. CancerGene ARA EW;Bercovitch L;Marais AS;Terry SF;Viljoen DL;Boyd CD Evidence for a founder effectfor pseudoxanthoma elasticum in the Afrikaner population of South Africa. http://caroll.vjf.cnrs.fr/cancergene/CG1038.html

Infobiogen Search CancerGene CancerGene Homepage Search CancerGene Citations CancerGene Card Symbol ARA Aliases Name anthracycline resistance-associated Locus OMIM GDB SwissProt LocusLink ARA Class RELONC Keywords ABC transporter Diseases Drug Resistance, Multiple; Drug Resistance, Neoplasm; Leukemia; Leukemia, T-Cell Comments ATP-binding cassette (ABC), ATP-dependent transporters are a large superfamily of proteins that include the multidrug resistance proteins, P-glycoprotein ( CG:400 ) and MRP (multidrug resistance protein, CG:360 ). The ARA (anthracycline resistance-associated) gene that codes for a putative member of the ABC transporters has recently been cloned ( UI:97069542 ) and shown to have high sequence homology to the gene for MRP. Kuss et al. (1994, UI:94276679 ) have previously shown MRP to be deleted in a subset of inv(16) leukemic patients. The deletion of MRP was associated with an improved patient survival compared with inv(16) patients who did not have such a deletion ( UI:96430264 ). Kuss et al. (1998, UI:98389632 ) have mapped the ARA gene to 16p13.1, in the same physical interval as the inv(16) short-arm breakpoint. It is shown to be situated proximal to both MYH11 (

70. Grönblad-Strandberg Syndrome (www.whonamedit.com) GrönbladStrandberg-Touraine syndrome Marchesani-Wirz syndrome Touraine’s syndromeI Synonyms Angioid streaks-pseudoxanthoma elasticum syndrome, elastica http://www.whonamedit.com/synd.cfm/1059.html

Home List categories Eponyms A-Z Biographies by country ... Contact Grönblad-Strandberg syndrome Also known as: Darier-Grönblad-Strandberg syndrome Grönblad-Strandberg-Touraine syndrome Marchesani-Wirz syndrome Touraine’s syndrome I Synonyms: Angioid streaks-pseudoxanthoma elasticum syndrome, elastica disease, elastorrhexis generalisata, elastosis dystrophica, elastosis dystrophica, pseudoxanthoma elasticum (PXE), pseudoxanthoma elasticum with angioid streaks in the retina, systemic elastodystrophy, systemic elastorrhexis. Associated persons: Ferdinand-Jean Darier Ester Elizabeth Grönblad Oswald Marchesani James Victor Strandberg ... Franz Wirz Description: A rare hereditary disorder with degenerated elastic fibres present in the skin, blood vessels and heart, due to calcification of elastic fibres. The skin abnormalities present with raised, soft yellowish papules, especially around the mouth, neck, axillae, elbows, groin, and periumbilical areas, sometimes involving most parts of the skin. The skin has been likened to the appearance of the skin of a plucked chicken. Ocular features usually include angioid streaks, retinal haemorrhage, loss of visual acuity, and, sometimes, macular degeneration and chorioretinitis. Cardiovascular complications generally consist of absence of the pulse in the arms and legs, intermittent claudication, hypertension, angina pectoris, peripheral periarterial calcification, and stenosis of the celiac artery. There are four genetically distinct variants - 2 dominant and 2 autosomal recessive forms. It occurs in the second decade of life or later, more often in females, and frequently in consanguineous marriages. Occasionally associated with Paget’s syndrome, Marfan’s syndrome, Herrick’s syndrome, Albers-Schönberg’s syndrome.

71. Y. Ralph Chu, MD - Eye Conditions - Pseudoxanthoma Elasticum Y. Ralph Chu, MD. Home Conditions pseudoxanthoma elasticum, http://doctorchu.eyemdlink.com/Condition.asp?ConditionID=368

72. Kasuistik 07 Translate this page Kasuistik 07. pseudoxanthoma elasticum. h10. 25- und 31-jährigeSchwestern - bei beiden kommt es seit einigen Jahren insbesondere http://www.derma.de/ddg/inhalt/kasuistiken/kasuistik_7/kasuistik_07.html

73. Pseudoxanthoma Elasticum pseudoxanthoma elasticum. Definition ORGANIZATIONS. National Association for PseudoxanthomaElasticum. 1420 Ogden St., Denver, CO 802181910. (303) 832-5055. http://www.chclibrary.org/micromed/00062470.html

Main Search Index Definition Description Causes ... Resources Pseudoxanthoma elasticum Definition Pseudoxanthoma elascticum (PXE) is an inherited connective tissue disorder in which the elastic fibers present in the skin, eyes, and cardiovascular system gradually become calcified and inelastic. Description The course of PXE varies greatly between individuals. Typically it is first noticed during adolescence as yellow-orange bumps on the side of the neck. Similar bumps may appear at other places where the skin bends a lot, like the backs of the knees and the insides of the elbows. The skin in these areas tends to get thick, leathery, inelastic, and acquire extra folds. These skin problems have no serious consequences, and for some people, the disease progresses no further. Bruch's membrane, a layer of elastic fibers in front of the retina, becomes calcified in some people with PXE. Calcification causes cracks in Bruch's membrane, which can be seen through an ophthalmoscope as red, brown, or gray streaks called angioid streaks. The cracks can eventually (e.g., in 10-20 years) cause bleeding, and the usual resultant scarring leads to central vision deterioration. However, peripheral vision is unaffected. Arterial walls and heart valves contain elastic fibers that can become calcified. This leads to a greater susceptibility to the conditions that are associated with hardening of the arteries in the normal aging populationhigh blood pressure

74. Thomas W. Samuelson, MD - Eye Conditions - Pseudoxanthoma Thomas W. Samuelson, MD. Home Conditions pseudoxanthoma elasticum, http://drsamuelson.eyemdlink.com/Condition.asp?ConditionID=368

75. Health Library - Pseudoxanthoma Elasticum Advanced Search. pseudoxanthoma elasticum. Self Help Clearinghouse. National Associationfor pseudoxanthoma elasticum (NAPE). National network. http://www.stjudemedicalcenter.org/Library/HealthGuide/SelfHelp/topic.asp?hwid=s

76. Page Not Found 2.9.3 pseudoxanthoma elasticum. Introduction Special staining for calciumphosphate (Kossa) pseudoxanthoma elasticum, calcium (Kossa) 20x (468). http://atlases.muni.cz/atl_en/main nenadory disordersela.html

Page not Found Technical administrator MU The page you ask for does not exist on our server. If you entered the URL manually please check it for mistyping. If you arrived to this page by clicking a link on some other page please contact the author of the referring page.

77. Atlas Of Dermatology Myxedema. Pretibial myxedema, alcian blue 40x Pretibial myxedema, alcianblue 5x Pretibial myxedema, HE 5x pseudoxanthoma elasticum. http://atlases.muni.cz/atl_en/aul-pock-en.html

Atlas of dermatology Lumir Pock doc, MD, PhD Hidrocystoma, apocrine Hidrocystoma, apocrine, HE 20x Hidrocystoma, apocrine, HE 40x Pseudopelade of Brocq Pseudopelade of Brocq, late, HE 10x Pseudopelade of Brocq, late, HE 40x Pseudopelade of Brocq, late, HE 5x Pseudopelade of Brocq, late; section parallel to epidermal surface, HE 5x Chondroid syringoma, apocrine Chondroid syringoma, apocrine, HE 20x Chondroid syringoma, apocrine, HE 40x Cryoglobulinemia Cryoglobulinemia (monoclonal), HE 10x Cryoglobulinemia (monoclonal), HE 20x Cryoglobulinemia (monoclonal), HE 5x Fibroma Sclerosing fibroma, HE 20x Sclerosing fibroma, HE 2x Hidradenoma papilliferum Hidradenoma papilliferum, HE 10x Hidradenoma papilliferum, HE 40x Keratosis pilaris Keratosis pilaris, HE 10x Keratosis pilaris, HE 40x Lichen planopilaris Lichen planopilaris, HE 20x Lichen planus hypertrophic Lichen verrucosus (hypertrophic), HE 40x Lichen verrucosus, HE 5x Median raphe cyst Median raphe cyst, HE 20x Median raphe cyst, HE 40x Myxedema Pretibial myxedema, alcian blue 40x Pretibial myxedema, alcian blue 5x Pretibial myxedema, HE 5x Pseudoxanthoma elasticum Pseudoxanthoma elasticum, elastic fibres 20x

78. Pseudoxanthoma Elasticum pseudoxanthoma elasticum,, Print this article, genetic disorder of connectivetissue causing fragmentation and calcification of elastic fibres. http://www.amershamhealth.com/medcyclopaedia/Volume V 2/pseudoxanthoma elasticum

Medcyclopaedia About Medcyclopaedia Amersham Health Search for: Type a word or a phrase. All forms of the word are searchable. Advanced search Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search *For Medical Professionals only, registration required Pseudoxanthoma elasticum, genetic disorder of connective tissue causing fragmentation and calcification of elastic fibres. Pseudoxanthomas, yellow papules, are present on the neck, cubital fossa, popliteal fossa and groin. Gastrointestinal haemorrhage is frequent due to abnormal mucosal arterioles. Premature atherosclerosis of the coronary arteries is the major cardiovascular manifestation. Endocardial fibroelastosis and mitral valve prolapse are occasionally associated cardiac lesions. CBH The Encyclopaedia of Medical Imaging Volume V:2 Welcome to Medcyclopaedia. This site is open to a public audience, still we want to know a little more about our visitors. Please tick off the boxes that match your profile. Do you live in Europe?

79. Zebra Card EY-801: Pigmented Vessel-like Streaks pseudoxanthoma elasticum, Paget disease of bone, sickle cell disease, pituitarytumors, familial hyperphosphatemia with metastatic calcification. http://www.zebracards.com/EY-801.html

Zebra Cards Update Eye EY-801 Nav Broad lines of pigment radiating from the optic disk and branching in the manner of blood vessels Differential Diagnosis Top Nav pseudoxanthoma elasticum, Paget disease of bone, sickle cell disease, pituitary tumors, familial hyperphosphatemia with metastatic calcification Discussion not available online Top Nav Update Comments Top Nav Look for PXE in all your patients with premature, or not so premature, coronary disease. [ Shows typical axillary skin condition. [ Footnotes in Print Edition Top Nav Angioid streaks. Clarkson JG, Altman RD. Surv Ophthalmol 1982 Mar-Apr;26(5):235-46. Pubmed+Abstract Similars An internist looks at the fundus oculi. Sapira JD. Dis Mon 1984 Nov;30(14):1-64. Pubmed+Abstract Similars Physician's Guide to Oculosystemic Diseases Delaney WV. Oradell, NJ: Medical Economics, 1982: 356-358. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1983. Gastrointestinal bleeding with ocular and cutaneous abnormalities. N Engl J Med 1983 Mar 10;308(10):579-85.

80. WebGuest - Open Directory : Health : Conditions And Diseases : Genetic Disorders Health Conditions and Diseases Rare Disorders (128). Sites MyLifePath An in depth look at pseudoxanthoma elasticum. NORD - Pseudoxanthoma http://directory.webguest.com/index.cgi/Health/Conditions_and_Diseases/Genetic_D

Browse thru 1000's of books about health, mind and body: About Us Privacy Statement Acceptable Use Policy Legal Notices ... Contact Us the entire directory only in Top Health Conditions and Diseases Genetic Disorders : Pseudoxanthoma Elasticum See also: Health: Conditions and Diseases: Cardiovascular Disorders: Vascular Disorders Health: Conditions and Diseases: Musculoskeletal Disorders: Connective Tissue Health: Conditions and Diseases: Rare Disorders Sites: MyLifePath - An in depth look at Pseudoxanthoma elasticum. NORD - Pseudoxanthoma Elasticum - Offers alternative names, a general discussion and resources for PXE. PXE International - The comprehensive source for pseudoxanthoma elasticum research and world wide activities. VhiHealth-e - A definition of Pseudoxanthoma elasticum followed by a description, causes and symptoms, diagnosis, treatment options, prognosis and prevention. Last update: 5:55 PT, Saturday, March 17, 2001 Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor

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