41. Reiter's Syndrome (Reactive Arthritis) In the Spotlight. April 19, 2000. Reiter's Syndrome (reactive arthritis).By Nick Shah, MD Kenneth Song, MD Personal MD.com Contributing Writers. http://www.personalmd.com/news/reiters_syndrome_041900.shtml

Home Noticias de Salud Family Centers Health Centers ... My Health Manager Search PersonalMD Services Family Health Women's Health Children's Health ... Health Encyclopedia In the Spotlight April 19, 2000 Reiter's Syndrome (Reactive Arthritis) By Nick Shah, MD Kenneth Song, MD Personal MD.com Contributing Writers Reiter's syndrome, also known as reactive arthritis, is an arthritis usually associated with an infection elsewhere in the body, especially the gut (intestines) and genitals. It is the most common type of arthritis affecting young men, with men between the ages of 20 and 40 most likely to develop it. Reiter's syndrome belongs to a group of disorders collectively termed the spondyloarthropathies. These disorders are characterized by arthritis of varying degree and a genetic risk factor by carrying the gene HLA-B27. Other diseases in this group of disorders include psoriatic arthritis, ankylosing spondylitis, and colitic arthritis, which is associated with inflammatory bowel disease. How does it occur?

42. Dietary Glycine Prevents Peptidoglycan Polysaccharide-Induced Reactive Arthritis Dietary Glycine Prevents Peptidoglycan PolysaccharideInduced reactive arthritisin the Rat Role for Glycine-Gated Chloride Channel Xiangli Li, 1 ,2 Blair U. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=98707

43. Reactive Arthritis And Ankylosing Spondylitis: Clinical Chlamydiae.com. The page you have accessed is restricted please login.If you have come here from an external search engine it is http://www.chlamydiae.com/chlamydiae/restricted/docs/infections/arthritis_presen

Home News FAQ Chlamydiales ... Links Chlamydiae.com The page you have accessed is restricted please login- If you have come here from an external search engine it is because the page you want requires registration. Registration is quick, free of charge and gives you access to the full site. You may wish to visit the home page first to see what this comprehensive site is about. If all you want is basic information about chlamydial genital tract infections, click health information If you wish to register straight away, please click register now E-Mail Address: Password: Tick this box to remember your login (not recommended for users of shared computers)

44. Frequently Asked Questions About Reactive Arthritis reactive arthritis is a form of arthritis or joint inflammation thatoccurs as a. NIH pub. 025039 What Is reactive arthritis? http://www.arthritissupport.com/library/showarticle.cfm/ID/549/T/Arthritis

Arthritis Support .com One of the World's Largest Arthritis Site! Over 3 million Annual Visitors 1,000+ Arthritis 300 Arthritis Items Health Watch Newsletter The Latest News Articles The Latest Abstracts ... The Latest Drug News Search Our Site Arthritis Info. OsteoArthritis Rheumatoid Arthritis Arthritis Support Treatment Support Groups Message Boards Doctor Referral ... 10 Coping Tips Health Resources Aids Chat Alzheimer's Chronic Fatigue Depression Chat ... Weight Loss Free Catalog Advertisement Frequently Asked Questions About Reactive Arthritis arthritissupport.com Note: The following article is reprinted from the National Institute of Arthritis and Musculoskeletal and Skin disease. NIH pub. # 02-5039 What Is Reactive Arthritis? Reactive arthritis is a form of arthritis or joint inflammation that occurs as a "reaction" to an infection elsewhere in the body. Inflammation is a characteristic reaction of tissues to injury or disease and is marked by swelling, redness, heat, and pain. Besides this joint inflammation, reactive arthritis is associated with two other symptoms: redness and inflammation of the eyes (conjunctivitis) and inflammation of the urinary tract (urethritis). These symptoms may occur alone, together, or not at all. Reactive arthritis is also known as Reiter's syndrome, and your doctor may refer to it by yet another term, as a seronegative spondyloarthropathy. The seronegative spondyloarthropathies are a group of disorders that can cause inflammation throughout the body, especially in the spine. (Examples of other disorders in this group include psoriatic arthritis, ankylosing spondylitis, and the kind of arthritis that sometimes accompanies inflammatory bowel disease.)

45. Q & A Reactive Arthritis; Yoga For Arthritis; Bracelets For Pain Relief? to ArthritisSupport.com's email news bulletin FEATURES November 13, 2002 * FrequentlyAsked Questions About reactive arthritis * Yoga – Relaxation and http://www.arthritissupport.com/library/showarticle.cfm/ID/551/T/Arthritis

Arthritis Support .com One of the World's Largest Arthritis Site! Over 3 million Annual Visitors 1,000+ Arthritis 300 Arthritis Items Health Watch Newsletter The Latest News Articles The Latest Abstracts ... The Latest Drug News Search Our Site Arthritis Info. OsteoArthritis Rheumatoid Arthritis Arthritis Support Treatment Support Groups Message Boards Doctor Referral ... 10 Coping Tips Health Resources Aids Chat Alzheimer's Chronic Fatigue Depression Chat ... Weight Loss Free Catalog Advertisement arthritissupport.com Thank you for subscribing to ArthritisSupport.com's email news bulletin FEATURES - November 13, 2002: * Frequently Asked Questions About Reactive Arthritis * Yoga – Relaxation and Relief for Arthritis Sufferers * Study Finds Ionized Bracelets Effective as Placebo for Musculoskeletal Pain SUPPORT and COPING * Got Questions? Here are answers... ENDNOTES * Refer a Friend * About Us Feature Articles Frequently Asked Questions About Reactive Arthritis Reactive arthritis is a form of arthritis, or joint inflammation that occurs as a "reaction" to an infection elsewhere in the body. Inflammation is a characteristic reaction of tissues to injury or disease and is marked by swelling, redness, heat, and pain. The following fact sheet details the characteristics of this disease and discusses potential treatment options. https://www.arthritissupport.com/track.cfm?id=992

46. Spondyloarthropathy And Reactive Arthritis Speciality Spotlight. Medicine. Spondyloarthropathy and reactive arthritis.DD Gladman, VT Farewell, K Wong et al (Univ of Toronto; Univ http://www.mdbrowse.com/Speciality/Medicine/Spondy&ReactiveArthritis.htm

Home Speciality Spotlight Medicine Spondyloarthropathy and Reactive Arthritis DD Gladman, VT Farewell, K Wong et al (Univ of Toronto; Univ College, London; McMaster Univ, Hamilton, Ont, Canada et al). Mortality studies in psoriatic Arthritis: Results from a Single Outpatient Center: II. Prognostic Indicators for Death Arthritis Rheum 41:1103-1110, 1998. Psoriatic arthritis has been considered benign arthropathy. However recent studies indicate that risk of death is elevated by 60% in patients with psoriatic arthritis. For some unknown reason the risk factor is less in presence of nail changes.

47. Reiter's Syndrome reactive arthritis. Pathophysiology Associated with HLAB27 genotype in 66% of patients; reactive arthritis may be initial presentation of HIV; http://www.fpnotebook.com/RHE124.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Spondylitis Assorted Pages Ankylosing Spondylitis Examination Laboratory Major Histocompatibility Complex Antigens Reiter's Syndrome Reiter's Disease Circinate Balanitis Reactive Arthritis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Spondylitis Index Ankylosing Reiter's Sn Definition Aseptic inflammatory polyarthritis Epidemiology Most common inflammatory polyarthritis in young men More commonly affects men by ratio of 9:1 to 5:1 Incidence : as high as 33 in 100,000 males

48. Psoriatic Arthritis Keratoderma blennorrhagica Hyperkeratotic Papules on plantar footsurface; Also seen in reactive arthritis (Reiter's Disease). Sausage http://www.fpnotebook.com/DER241.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Dermatology Rheumatology Dermatitis ... Hyperplasia Psoriatic Arthritis Assorted Pages Dermatomyositis Psoriatic Arthritis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Dermatology Index Acne Allergy Bacteria Blister Cardiovascular Medicine Dermatitis Dry Endocrinology Environmental Injury Examination Ophthalmology Fungus Hair Hematology and Oncology Hyperplasia Infectious Disease Laboratory General Nails Parasite Pediatrics Pharmacology Pigment Prevention Procedure Psychiatry Rheumatology Sebaceous Sports Medicine Sweat Symptom Evaluation Wart Page Rheumatology Index Dermatitis Dermatomyositis Hyperplasia Psoriasis Arthritis See Also Psoriasis Epidemiology Incidence : affects 7% of Psoriasis patients Forms Distal Interphalangeal Arthritis (Classic, 5% of cases)

49. Reactive Arthritis reactive arthritis. Patients present with a sterile largejoint arthritisfollowing an infection. It is accompanied by back pain http://www.mds.qmw.ac.uk/biomed/kb/resources/immunology/immunologymellisa/diseas

Reactive arthritis Patients present with a sterile large-joint arthritis following an infection. It is accompanied by back pain and non articular symptoms such as balanitis, urethritis, cervicitis, keratoderma, blennorrhagicum, pericarditis and conjunctivitis. Clinical features more common in males acute, asymetrical lower limb arthritis occurs a days to weeks following an infection enthesitis (pain from where bone interfaces with a joint capsule, ligament or tendon) bilateral conjunctivitis Reiter's disease- triad of urethritis, arthritis and conjunctivitis Investigations ESR/CRP raised Anaemia Leucocytosis Rheumatoid factor negative Anti-nuclear antibodies negative Management Treat underlying infection if present NSAID and local corticosteroid injections for pain Disease modifying anti-rheumatic drugs (DMARD) for patients with relapsing arthritis e.g. s ulphasalazine, methotrexate, penicillamine etc. Back to Immunology Index

50. American Family Physician: What You Should Know About Reactive Arthritis. Web site. Page 1. What You Should Know About reactive arthritis. IssueAugust, 1999. What is reactive arthritis? reactive arthritis http://www.findarticles.com/cf_dls/m3225/2_60/55391944/p1/article.jhtml

Location: All Locations Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming Keyword: Find Articles Home View By Subject View By Name Search Tips ... Help Search all magazines this magazine Arts/Entertain. Automotive Business/Fin. Comp./Tech. Health/Fitness Home/Family News/Society Reference/Ed. Sports for Search Tips : Use quotes to find a specific phrase, e.g. "Abe Lincoln" or "New York". Use the + sign for words that MUST be in the article, e.g. +Ford +SUV Terms related to this article: Infectious arthritis Care and treatment Buy and sell " " and millions of other items at eBay American Family Physician Search this Magazine Go to Web site Print this article Email this article Page: What You Should Know About Reactive Arthritis.

51. Surgery Door - Medical Conditions What is reactive arthritis ? The joint is made up of two boneends, eachcovered with a layer of cartilage. How does reactive arthritis occur ? http://www.surgerydoor.co.uk/medcon/detail2.asp?level2=Reactive Arthritis

52. Arthritis Insight-For Our Family & Friends-Significant Other Spot reactive arthritis reactive arthritis, formerly known as Reiter's Syndrome, isone of the spondyloarthropathies that is being diagnosed more and more. http://arthritisinsight.com/living/family/sos/reactive.html

In this section: Significant Other Spot We Say 21 Guidelines to Caregiving Fatigue Factor Letter To Our Loved Ones Sylvia's Letter To Her Loved Ones Jill's Story Tracey's Story Jodie's Story Links For More Learning Current Discussion Archives Survey Disease Index ... Better Living Significant Other Spot Significant Other Spot Reactive Arthritis Reactive arthritis, formerly known as Reiter's Syndrome, is one of the spondyloarthropathies that is being diagnosed more and more. Arthur-itis, being the shrewd beast he is, has put together a puzzling combination for this one. Reactive arthritis develops as a reaction to some other kind of infection. The body reacts after the infection by showing swollen joints, inflammation of the lower spine, and the characteristic conjunctivitis around the eyes and urethral and or bowel inflammation. This type of arthritis often involves very sore and inflamed Achilles tendons of the heel, as well. The HLA-B27 gene can be pointed to as a marker of the tendency to develop reactive arthritis. The diseases that this kind of arthritis can develop in response to ( auto-immune reaction) range from food poisoning to STD's to HIV infection. Stress contributes to the recurrence of symptoms in sufferers.

53. Reactive Arthritis - Arthritis: Health And Medical Information About Arthritis A reactive arthritis (Formerly Reiter Syndrome). What is reactive arthritis? Reactivearthritis is considered a systemic rheumatic disease. http://www.medterms.com/Reactive_Arthritis/article.htm

MedicineNet Home FocusOn Arthritis Diseases and Conditions Index Reactive Arthritis FocusOn Arthritis The doctors of MedicineNet who wrote and edited the new edition of Webster's New World™ Medical Dictionary packed it with information about diseases medications , and medical procedures and tests 32 additional Reactive Arthritis related articles click here Page Next Reactive Arthritis (Formerly Reiter Syndrome) What is Reactive Arthritis? What causes Reactive Arthritis? What are symptoms of Reactive Arthritis? How is Reactive Arthritis diagnosed? ... Reactive Arthritis At A Glance What is Reactive Arthritis? Reactive arthritis is a chronic form of arthritis featuring the following three conditions: (1) inflamed joints; (2) inflammation of the eyes (conjunctivitis); and (3) inflammation of the genital, urinary or gastrointestinal systems. This form of joint inflammation is called "reactive arthritis" because it is felt to involve an immune system which is "reacting" to the presence of bacterial infections in the genital, urinary, or gastrointestinal systems. Accordingly, certain people's immune systems are genetically primed to react aberrantly when these areas are exposed to certain bacteria. The aberrant reaction of the immune system leads to spontaneous inflammation in the joints and eyes. This can be confounding to the patient and the doctor when the infection has long passed at the time of presentation with arthritis or eye inflammation.

54. Abstract: Reactive Arthritis And Other Sequelae Following Sporadic Salmonella Ty reactive arthritis and Other Sequelae Following Sporadic Salmonella typhimuriumInfection in British Columbia, Canada A Case Control Study http://www.jrheum.com/abstracts/abstracts02/2154.html

Search the Journal Home Current Issue Archives Guidelines for Authors ... Contact Info Reactive Arthritis and Other Sequelae Following Sporadic Salmonella typhimurium Infection in British Columbia, Canada: A Case Control Study JANE A. BUXTON, MURRAY FYFE, SAMARA BERGER, MICHELLE B. COX, KIMBERLY A. NORTHCOTT, and the Multiprovincial Salmonella typhimurium Case-Control Study Group ABSTRACT Objective . To describe sequelae occurring in the 3 months after sporadic Salmonella typhimurium (ST) infection in British Columbia (BC), Canada. We compared the incidence of sequelae to similar symptoms in controls; identified risk factors for developing sequelae; identified the incidence of reactive arthritis (ReA) as diagnosed by a rheumatologist, and assessed primary care physician diagnosis of ReA. A questionnaire was administered by telephone to cases of ST occurring in BC between December 1, 1999, and November 30, 2000; and to controls obtained from the BC provincial client registry. Cases reporting symptoms were followed up by a rheumatologist. Thirty-five of 66 (53%) cases reported any symptom, 17 (26%) reported joint symptoms. The Mantel-Haenszel odds ratio (weighted by sex and pediatric/adult) of a salmonella case reporting "any symptom" compared to controls was 5.42; 95% confidence interval (CI) 2.18-16.27; and reporting joint symptoms was 4.40; 95% CI: 1.25-19.53. The sex distribution of cases reporting joint symptoms was not significantly different. No medication taken during the salmonella infection was significantly different between the cases who had joint symptoms and those who did not. Four cases (2 adults, 2 children) were considered by the rheumatologist to have symptoms consistent with ReA, 2 of these had been told by a physician that their symptoms were related to their ST infection.

55. Full Text: Sporadic Enteric Reactive Arthritis And Undifferentiated Spondyloarth the candidate bacterial trigger and cytokine profile of synovial fluid mononuclearcells (SFMC) in patients with sporadic enteric reactive arthritis (ReA) and http://www.jrheum.com/abstracts/abstracts03/105.html

Search the Journal Home Current Issue Archives Guidelines for Authors ... Contact Info Sporadic Enteric Reactive Arthritis and Undifferentiated Spondyloarthropathy: Evidence for Involvement of Salmonella typhimurium RAJESH SINHA, AMITA AGGARWAL, KASHINATH PRASAD, and RAMNATH MISRA ABSTRACT. To define the candidate bacterial trigger and cytokine profile of synovial fluid mononuclear cells (SFMC) in patients with sporadic enteric reactive arthritis (ReA) and undifferentiated spondyloarthropathy (uSpA). The study group comprised 10 patients with ReA and 23 with uSpA who fulfilled European Spondylarthropathy Study Group criteria. Ten patients with rheumatoid arthritis (RA) served as disease controls. IgG, IgA, and IgM antibodies to Shigella flexneri Salmonella typhimurium , and Yersinia enterocolitica were measured in sera and SF by ELISA. Peripheral blood mononuclear cell (PBMC) and SFMC proliferation assays were done in the presence or absence of crude bacterial lysates. Bacterial antigens and DNA in synovial cells were detected by indirect immunofluorescence and polymerase chain reaction, respectively. Interferon- g (IFN- g ), interleukin 10 (IL-10), and IL-4 were measured in 18 h SFMC culture supernatants in presence of bacterial lysate.

56. Healthfinder® — Questions And Answers About Reactive Arthritis Questions and Answers About reactive arthritis. internet URL. http//www.niams.nih.gov/hi/topics/reactive/reactive.htm.sponsoring agency. http://www.healthfinder.gov/Scripts/ShowDocDetail.asp?doc=4468&lang=1

57. Infectious Arthritis | Ahealthyme.com This is called reactive arthritis. reactive arthritis can result from a bout ofsalmonella, shigella, and campylobacter contracted through food poisoning. http://www.ahealthyme.com/topic/infectiousarthritis

Search AHealthyMe! Personalize AHealthyMe! Sign up for our Newsletter! You are here: Home Infectious Arthritis By Chris Woolston Below: Who's at risk Diagnosis Treatment The long-term outlook When we think of invading bacteria, we usually don't think of our joints as a potential target. But if there's an infection somewhere in your body, the germs can travel through your bloodstream to attack a joint. Bacteria can also enter a joint directly, either right after surgery or from an injury, for example. Either way, the infected joint becomes swollen, inflamed, and painful. Doctors call this condition septic arthritis, bacterial arthritis, or infectious arthritis. Germs don't have to invade a joint to cause arthritis. Some types of infections can trigger an unusual reaction in the body that results in widespread inflammation, pain, and swelling in the joints. This is called reactive arthritis. Reactive arthritis can result from a bout of salmonella, shigella, and campylobacter contracted through food poisoning. A case of reactive arthritis can also follow certain sexually transmitted infections, including chlamydia, gonorrhea, and HIV. Both septic arthritis and reactive arthritis can cause pain and swelling in a joint. Septic arthritis most often occurs in one joint, usually a knee, shoulder, or wrist, but it can involve several. It typically causes a mild fever, and the patient may feel like it's impossible to move the joint.

58. Bacterium-specific Synovial Lymphocyte Proliferation In Reactive Arthritis Longitudinal investigation of bacteriumspecific synovial lymphocyteproliferation in reactive arthritis and lyme arthritis. The http://www.cfsresearch.org/chlamydia/linkschronic/20nf.htm

The British Journal of Rheumatology, Vol 37, 784-788, ORIGINAL PAPERS Longitudinal investigation of bacterium-specific synovial lymphocyte proliferation in reactive arthritis and lyme arthritis C Fendler, P Wu, U Eggens, S Laitko, H Sorensen, A Distler, J Braun and J Sieper Deutsches Rheumaforschungszentrum, Department of Nephrology and Rheumatology, Klinikum Benjamin Franklin, Berlin, Germany. Reprinted with permission of Oxford University Press and the British Society for Rheumatology Abstract: BACKGROUND: Antigen-specific lymphocyte proliferation of synovial fluid mononuclear cells (SF MNC) has been reported repeatedly in reactive arthritis and Lyme arthritis; however, less information is available on serial investigations of SF MNC in the same patients. METHODS: In this study, the synovial lymphocyte proliferation to Yersinia, Chlamydia, Shigella and Borrelia burgdorferi was investigated sequentially at different time points in 28 patients with reactive arthritis, undifferentiated oligoarthritis or Lyme arthritis responding to one of these bacteria. RESULTS: The same bacterium was always recognized in arthritis triggered by Chlamydia, Shigella or Borrelia, with much variation in the proliferative response. Only the Yersinia-specific responses changed specificity, suggesting that the proliferative response to Yersinia is non-specific in some patients.

59. Chlamydia Trachomatis Antibody Detection And Diagnosis Of Reactive Arthritis Society for Rheumatology ORIGINAL PAPERS. Chlamydia trachomatis antibodydetection and diagnosis of reactive arthritis. S Bas and http://www.cfsresearch.org/chlamydia/detection/12nf.htm

The British Journal of Rheumatology, Vol 37, 1054-1059, ORIGINAL PAPERS Chlamydia trachomatis antibody detection and diagnosis of reactive arthritis S Bas and TL Vischer Department of Internal Medicine, University Hospital, Geneva, Switzerland. Reprinted with permission of Oxford University Press and the British Society for Rheumatology Abstract: OBJECTIVE: To investigate whether determining the presence of serum or synovial fluid (SF) IgG and IgA of anti-Chlamydia antibodies with two recent commercially available enzyme-linked immunosorbent assays (ELISA) using synthetic peptides or recombinant antigen could be helpful to detect possible Chlamydia trachomatis (CT)-involved disease in rheumatological patients without evidence of urogenital CT infection. METHODS: The prevalence of such antibodies was determined in samples from patients with well-defined disease, i.e. CT sexually acquired arthritis and from patients with other inflammatory arthropathies unrelated to CT. RESULTS: When considering IgG and/or IgA anti-MOMP or anti-LPS antibodies, a sensitivity of 100% was obtained for serum and SF samples, but with a low specificity. A sensitivity and a specificity equal or close to 80% were observed for the SF IgG anti- MOMP antibodies.

60. Etiopathogenesis Of Rheumatoid Arthritis The working hypothesis of the project is based on our previous and ongoing researchin reactive arthritis (ReA). Toivanen A. Managing reactive arthritis. http://www.utu.fi/research/tic/projects/toivanen.html

Etiopathogenesis of Rheumatoid Arthritis Contact Information Paavo Toivanen, M.D., Professor Emeritius of Bacteriology and Serology ( paavo.toivanen@utu.fi Address: Prof. Paavo Toivanen Department of Medical Microbiology Turku University Kiinamyllynkatu 13 FIN-20520 Turku, Finland Description of the Project The goal of this project is to clarify the etiopathogenesis of rheumatoid arthritis (RA). It is the most crippling disease in the world affecting 100-200 million people. In Finland alone, 1,000 persons are transferred to disability pension each year, due to RA and related disorders. No specific treatment of RA exists. Such a treatment and means for prophylaxis can only be developed when the etiology and etiopathogenesis of RA have been clarified. Until that, the economic and social consequences of rheumatoid arthritis, including the human suffering, remain unmeasurable. The working hypothesis of the project is based on our previous and ongoing research in reactive arthritis (ReA). The hypothesis predicts that RA is caused and maintained by unknown factors X and Y, out of which one or both represent microbes or microbial degradation products. They may be identical or different. They may be exogenous, endogenous or belong to the normal microbial flora. For development of the disease, a mutual contribution of the causative factors and the genetically susceptible host is required. Particular emphasis is given to extension and application to RA of our previous results, which have in ReA revealed the significance of the intestinal flora as well as the presence of microbial products at the site of inflammation.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 3     41-60 of 102    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20