61. Retinopathy Of Prematurity Fibroplasia). What is retinopathy of prematurity? Information from Country HillsEye Center. retinopathy of prematurity Factsheet (from RNIB). Discussion http://www.nhbvi.com/internet/Eye/rop.html

Search: (may be referred to as Retrolental Fibroplasia) What is Retinopathy of Prematurity? Information from Country Hills Eye Center Information for Parents of Preemies Information from Prevent Blindness in Premature Babies Information from SpedEx ... Retinopathy of Prematurity Factsheet (from RNIB) Discussion, Publications, and Support Association for Retinopathy of Prematurity and Related Retinal Diseases (ROPARD) Online ROP Support Group Prevention, Research, and Treatment American Academy of Pediatrics' Policy Statement: Screening Examiation of Premature Infants for Retinopathy of Prematurity Baby-Blinding Retinopathy of Prematurity and Intensive Care Nursery Lighting Link Lists Disability Resources, Inc. Family Village Low Vision Gateway Sarah Blake's ROP/RLF Links and Resources Personal Web Pages Sarah Blake's ROP Information and Resources

62. RMROP -Retinopathy Of Prematurity Home Page Risk Management of retinopathy of prematurity (RMROP) Robert J. Hardy, Ph.D,Betty Tung, MS, Charles Cooper, MS RM-ROP is a Microsoft Access® Database http://www.sph.uth.tmc.edu/rmrop/

The University of Texas-Houston School of Public Health Risk Management of Retinopathy of Prematurity (RM-ROP) Robert J. Hardy, Ph.D, Betty Tung, M.S., Charles Cooper, M.S. Click Here if you wish to down load a copy of this database system. UTSPH Home Page Last updated: 04/25/97

63. Eye Conditions > Retinopathy Of Prematurity -- EyeMDLink.com Last Updated 10/21/2001. retinopathy of prematurity. Also referredto as Retrolental Fibroplasia. This retina lacks a normal blood http://www.eyemdlink.com/Condition.asp?ConditionID=393

64. Retinopathy Of Prematurity retinopathy of prematurity up. retinopathy of prematurity, One in a seriesof guidance notes produced by the Royal College of Ophthalmologists http://omni.ac.uk/browse/mesh/detail/C0035344L0035344.html

Retinopathy of Prematurity [up] Related topics: other Diabetic Retinopathy Retinal Detachment Retinal Perforations Retinal Vein Occlusion ... Retinopathy of prematurity One in a series of guidance notes produced by the Royal College of Ophthalmologists, on topics of interest to the profession. This guidance is on prematurity, an important cause of childhood blindness, and covers classification of retinopathy of prematurity by zone, epidemiology, screening, sequelae, and treatment. References are provided. Practice Guideline [Publication Type] Retinopathy of Prematurity Last modified 28/Mar/2003 [Low Graphics]

65. Retinopathy Of Prematurity retinopathy of prematurity, One in a series of guidance notes produced by theRoyal College of Ophthalmologists, on topics of interest to the profession. http://omni.ac.uk/whatsnew/detail/4019447.html

Back to whats new page. Retinopathy of prematurity One in a series of guidance notes produced by the Royal College of Ophthalmologists, on topics of interest to the profession. This guidance is on prematurity, an important cause of childhood blindness, and covers classification of retinopathy of prematurity by zone, epidemiology, screening, sequelae, and treatment. References are provided. Practice Guideline [Publication Type] Retinopathy of Prematurity Last modified 8/Jul/2002 [Low Graphics]

66. Nature Publishing Group Clinical Study. retinopathy of prematurity in the UK I The organisationof services for screening and treatment. L Haines 1 , AR http://www.nature.com/cgi-taf/DynaPage.taf?file=/eye/journal/v16/n1/abs/6700030a

67. Nature Publishing Group retinopathy of prematurity in the UK I The organisation of services for screeningand treatment. An international classification of retinopathy of prematurity. http://www.nature.com/cgi-taf/DynaPage.taf?file=/eye/journal/v16/n1/full/6700030

68. Retinopathy Of Prematurity -- An Epidemiological Perspective - For Parents And E Summer 2002. retinopathy of prematurity An Epidemiological Perspective. http://www.lighthouse.org/envision/summer2002/retinopathy_of_prematurity.htm

Summer 2002 Retinopathy of Prematurity An Epidemiological Perspective ROP A Disease of Developing Retinal Blood Vessels Fluorescein Angiograms The First Images of an ROP Lesion The Stages of ROP Opening International Discussions Prevalence of ROP in a few countries that supply statistics Vast improvements in neonatal care over the past few decades have resulted in the saving of many premature babies who never would have survived just 20 or 30 years ago. Extremely low birth weight babies are living today at a rate of 85-90 percent and in the best nurseries that we have in the US, well in excess of 90 percent. With the exportation of modern neonatology to developing nations, many more babies are surviving there, too. In developing countries, ROP is often not identified and treated. This is the case in much of Central and South America, so much so that at the Bascom Palmer Institute, once or twice a month and sometimes as often as three or four times we would see an 18-month or two-year-old child with stage 5 retinopathy of prematurity. No eye doctor had seen these children. In general, this is because ophthalmology has not kept pace with neonatology. In developing countries, ROP is largely ignored by ophthalmologists. Steps are just beginning to facilitate communication among ophthalmologists around the world to identify early cases of ROP. Among them is the creation of a universal classification system that allows us to discuss ROP with ophthalmologists worldwide, which has been established already. A second step is the use of digital imaging to share images of neonates' eyes at risk for end-stage ROP. Digital imaging has provided a means for non-ophthalmologists to help screen for ROP by using a digital camera and a high-speed modem that can instantaneously send a high-quality image to an expert in this disease.

69. Randomized Clinical Trials In The Treatment Of Retinopathy Of Prematurity - Envi Summer 2002. Randomized Clinical Trials in the Treatment of retinopathy of prematurity. Clinicaltrials for retinopathy of prematurity (ROP) are not new. http://www.lighthouse.org/envision/summer2002/treatment.htm

Summer 2002 Randomized Clinical Trials in the Treatment of Retinopathy of Prematurity Michael X. Repka, MD Clinical trials for retinopathy of prematurity (ROP) are not new. Clinical research into the disease at least its ocular manifestations dates back more than 50 years. Research has led to enhanced prevention of the disease as well as improved outcomes of treatment. Improvements in the neonatal intensive care unit (NICU), in the training of NICU staff, and developments in the fields of neonatology and nutrition all of which have evolved over the last two decades have boosted prevention. And improved treatment includes all examinations and the latest interventions performed by an ophthalmologist. ROP research methods, like those of any disease, include observational studies, in which its natural history is monitored; and case series, in which an assessment is made of the impact of changes in nursery care, the impact of a nutritional change or the impact of an intervention. These studies utilize patient populations drawn from two different time periods, and cannot account for other changes in care. Thus, such studies cannot prove the beneficial or deleterious effect of other changes. Randomized clinical trials are the most effective in proving the value of an intervention. This article examines clinical trials that have been part of research efforts to cure ROP.

70. COS - Policy Statements And Guidelines - Retinopathy Of Prematurity Guidelines for screening examinations for retinopathy of prematurity CanadianAssociation of Pediatric Ophthalmologists Ad Hoc Committee on Standards of http://www.eyesite.ca/english/program-and-services/policy-statements-guidelines/

Commentary .pdf file Policy Statements and Guidelines Guidelines for screening examinations for retinopathy of prematurity Canadian Association of Pediatric Ophthalmologists Ad Hoc Committee on Standards of Screening Examination for Retinopathy of Prematurity* Excerpted from the CJO, August 2000 Visual disability and blindness from severe retinopathy of prematurity (ROP) may be prevented with timely treatment during the evolution of stage 3 ROP.1 Accordingly, infants at risk must be examined to discover and to follow the development of ROP. The Canadian Ophthalmological Society, the Canadian Association of Pediatric Ophthalmologists and the Canadian Paediatric Society recommend the following guidelines for screening premature infants for ROP. Risk group Infants with a birth weight of 1500 g or less Examiners The examiner should be a skilled observer in the recognition of ROP, usually an ophthalmologist. Schedule of assessments The first examination should be performed 4 to 6 weeks after birth. A follow-up examination should be carried out approximately 2 weeks after every examination that reveals no ROP.5.

71. Quantifying Retinopathy Of Prematurity Quantifying retinopathy of prematurity. Outer ring is the magnifying glassused during eye exam. What is retinopathy of prematurity (ROP)? http://caddlab.rad.unc.edu/projects/RoP/

Main Members Projects Technologies ... Extras Projects: Overview Liver Transplant Planning and Assessment 3D Interactive Ultrasound Augmentation TIPS (Liver Shut Guidance) Neurosurgical Planning Tumor/AVM Segmentation Retinopathy of Prematurity Breast Cancer Detection and Diagnosis Lung Disease Detection and Diagnosis Quantifying Retinopathy of Prematurity Assisting in quantifying the dialation and tortuousness of retinal vessels in prematurely born infants Image from the head-mounted camera worn by clinician during eye exam. Outer ring is the magnifying glass used during eye exam. What is Retinopathy of Prematurity (ROP)? The internal surface of the back of the eye is lined by a tissue, called the retina. This tissue is equivalent to the film in a camera and is responsible for the initial formation of the visual image. This is then transmitted to the brain. In order to function, the retina requires a blood supply. The normal development of this blood supply for the retina starts at 16 weeks into a pregnancy and is completed by 36 weeks. If an infant is born prematurely, with the retinal blood vessel development incomplete, problems occur. Abnormal blood vessels may develop which can subsequently lead to bleeding and scar tissue formation. This may then stretch the retina pulling it out of position. Visual loss may result.

72. Computer Automated Quantification Of Plus Disease In Retinopathy Of Prematurity Computer Automated Quantification of Plus Disease in retinopathy of prematurity. References1. Cryotherapy for retinopathy of prematurity Cooperative Group. http://caddlab.rad.unc.edu/publications/Papers/AAPOS Abstract 2002b.htm

Computer Automated Quantification of Plus Disease in Retinopathy of Prematurity David K. Wallace, MD; Julien Jomier; Stephen R. Aylward, PhD; Maurice B. Landers III, MD Introduction: The accurate and timely determination of plus disease is very important to optimize the chance of a good visual outcome in infants with ROP. However, even for experienced examiners, it is very difficult to determine with certainty the degree of vascular change present. We have developed a computer program that captures digital images from a video indirect ophthalmoscope, identifies and traces the major posterior pole blood vessels, measures the dilation and tortuosity of each vessel, and calculates whether an eye has plus disease or not. Our purpose was to determine the accuracy of the computer program in comparison to two masked examiners. Methods: Posterior pole images from 20 premature infants, 10 normal and 10 representing various degrees of dilation and tortuosity, were randomly extracted from our video database and analyzed by both the computer program and by two masked examiners experienced in the diagnosis of ROP. The standard photograph from the CRYO-ROP study representing the minimum degree of dilation and tortuosity required for plus disease was also digitized, analyzed, and used as a numeric threshold for the automated determination of plus disease. Results: The examiners agreed on the presence or absence of plus disease in 17 of 20 cases. Of the 5 images determined to have plus disease by both examiners, 4 were calculated to have plus disease by the computer program. (80% sensitivity).

73. D-Penicillamine For Preventing Retinopathy Of Prematurity In Preterm Infants (Co DPenicillamine for preventing retinopathy of prematurity in preterm infants (CochraneReview). Background retinopathy of prematurity remains a common problem. http://www.cochrane.org/cochrane/revabstr/ab001073.htm

Abstract from The Cochrane Library , Issue 1, 2003 Click here to order the full review D-Penicillamine for preventing retinopathy of prematurity in preterm infants (Cochrane Review) Phelps DL, Lakatos L, Watts JL ABSTRACT A substantive amendment to this systematic review was last made on 13 November 2000. Cochrane reviews are regularly checked and updated if necessary. Background: Retinopathy of prematurity remains a common problem. A low rate of this disorder was unexpectedly observed among infants treated with intravenous d-penicillamine to prevent hyperbilirubinemia. This observation led to the investigation of its use to prevent retinopathy of prematurity. Objectives: To answer the question: Among very low birth weight infants, what is the effect of prophylactic administration of d-penicillamine on the incidence of acute ROP or severe ROP, and side effects including death? Search strategy: Searches were made of multiple electronic databases, previous reviews including cross references, abstracts, conference/symposia proceedings, and expert informants. The search was updated to November 2000. Selection criteria: Randomized or quasi-randomized controlled trials that administered d-penicillamine to infants less than 2000g birth weight within the day following birth were considered relevant to this review. Additional case series were examined for potential side effects.

74. Peripheral Retinal Ablation For Threshold Retinopathy Of Prematurity In Preterm Peripheral retinal ablation for threshold retinopathy of prematurity inpreterm infants (Cochrane Review). Andersen CC, Phelps DL. ABSTRACT http://www.cochrane.org/cochrane/revabstr/ab001693.htm

Abstract from The Cochrane Library , Issue 1, 2003 Click here to order the full review Peripheral retinal ablation for threshold retinopathy of prematurity in preterm infants (Cochrane Review) Andersen CC, Phelps DL ABSTRACT A substantive amendment to this systematic review was last made on 10 May 1999. Cochrane reviews are regularly checked and updated if necessary. Background: This section is under preparation and will be included in the next issue. Objectives: In premature infants with threshold retinopathy of prematurity (ROP) does peripheral retinal ablation, by any means, reduce the incidence of adverse ophthalmic outcome? Search strategy: The standard search strategy of the Cochrane Neonatal Review Group was used. This included a search of the Cochrane Neonatal Group Register of Clinical Trials, MEDLINE, EMBASE, previous reviews including cross references, abstracts from pediatric and ophthalmologic meetings, letters and expert informants. Search terms included "Retinopathy of Prematurity" [MeSH Terms], "Retrolental Fibroplasia" [All Fields] and "Lightcoagulation" [All Fields] or "Cryosurgery" [All Fields]. In addition, a personal bibliographic database was used as a cross-reference. Selection criteria: All trials in human premature infants with threshold ROP utilizing random or quasi random allocation to either peripheral retinal ablation of the avascular retina, by any means, or concurrent control group with independent outcome assessment were initially selected for review. Following methodologic review, only studies using random allocation were selected for data extraction.

75. Emory Eye Center—Research Important Clinical Research. retinopathy of prematurity. EEC Retinasurgeons regularly tote a portable diode laser to area hospitals http://www.emory.edu/EYE_CENTER/Research_and_Education/Research/retinopathy_rsrc

Important Clinical Research Retinopathy of prematurity Return to Research AIDS Glaucoma Low vision ... Macular degeneration Retinopathy of prematurity Strabismus Telemedicine Return to the Research and Education page.

76. Florida State University College Of Medicine Digital Library retinopathy of prematurity Patient/Family Resources. See also General OphthalmologyPatient/Family Resources; retinopathy of prematurity Clinical Resources. http://fsumed-dl.slis.ua.edu/patientinfo/ophthalmology/retinal/retinopathy-of-pr

Patient/Family Resources by Topic: Ophthalmology Retinopathy of Prematurity Patient/Family Resources Pediatrics Spanish Miscellaneous See also: General Ophthalmology Patient/Family Resources Retinopathy of Prematurity Clinical Resources Pediatrics MD Consult: Homepage Medical Library subscription INFO Patient Handouts Table of content Care of the Very Small Premature Infant: Access document Premature Babies - Caring for your Baby: Access document American Academy of Pediatrics (MEDEM): Homepage Public Education Brochures: List of documents Premature Babies: Special Health Issues: Access document American Academy of Ophthalmology (MEDEM): Homepage Medical Library: Table of contents Which Eye Conditions Affect Children?: Access document MEDLINE plus Medical Encyclopedia: Table of contents Retinopathy: English Spanish InteliHealth Disease and Condition Guide Table of contents Retinopathy: Access document Spanish MEDLINE plus Medical Encyclopedia: Table of contents Retinopathy: English Spanish Miscellaneous Retinopathy of Prematurity Patient/Family Resources National Library of Medicine MEDLINE plus Health Topics: Index Retinal Disorders: List of documents Eye Diseases (General): List of documents YAHOO - Health:Diseases and Conditions:Eye Conditions Additional Eye Conditions resources ( These sites have not been reviewed.

77. Florida State University College Of Medicine Digital Library retinopathy of prematurity Clinical Resources. retinopathy of prematurityAccess document; Extremely Low Birth Weight Infant Access document. http://fsumed-dl.slis.ua.edu/clinical/ophthalmology/retinal/retinopathy-prematur

Clinical Resources by Topic: Ophthalmology Retinopathy of Prematurity Clinical Resources Pediatrics Pathology Clinical Guidelines News ... Miscellaneous Resources See also: Eye Evaluation Clinical Resources General Ophthalmology Clinical Resources Retinopathy of Prematurity Patient/Family Resources Pediatrics Resources See also General Pediatrics Resources Yanoff: Ophthalmology 1st Ed.-1999 (MD Consult): Table of contents Medical Library subscription INFO Section 8 - Retina and Vitreous: Access document Chapter 19 - Vascular Disorders - Retinopathy of Prematurity: Access document Behrman: Nelson Textbook of Pediatrics 16th Ed.-2000 (MD Consult): Table of contents Medical Library subscription INFO Chapter 637 - Disorders of the Retina and Vitreous: Access document Retinopathy of Prematurity: Access document Johns Hopkins: Harriet Lane Handbook 16th Ed.-2002 (MD Consult): Table of contents Medical Library subscription INFO Chapter 17 - Neonatology: Access document Retinopathy of Prematurity: Access document Other MD Consult Reference Books Table of contents Medical Library subscription INFO All MD Consult Reference Books for The Merck Manual 17th Ed.-1999:

78. Retinopathy Of Prematurity retinopathy of prematurity. Definition retinopathy of prematurity is a disorderof retinal blood vessel development in the premature infant. http://www.pennhealth.com/ency/article/001618.htm

Disease Injury Nutrition Poison ... Prevention Retinopathy of prematurity Definition: The retina is the part of the eye which transmits visual information to the brain. Retinopathy of prematurity is a disorder of retinal blood vessel development in the premature infant . The severe form is characterized by retinal vascular proliferation , scarring, retinal detachment , and blindness. Alternative Names: Retrolental fibroplasia; ROP Causes, incidence, and risk factors: The blood vessels of the retina begin to develop three months after conception and complete their development at the time of normal birth. When an infant is born very prematurely, the infant's eye development will be disrupted. In infants who develop retinopathy of prematurity (ROP), the vessels grow abnormally from the retina into the normally clear gel that fills the back of the eye. Here, without support, the vessels are fragile and often hemorrhage into the eye. This is followed by scar tissue development which pulls the retina loose from the inner surface of the eye and draws it toward the center of the globe, producing a retinal detachment. This can reduce vision or, if severe, result in complete blindness Many premature infants develop transient and mild abnormal retinal blood vessel growth that converts to normal growth without treatment. Only approximately 1 out of 10 infants with early changes will progress to more severe retinal disease.

79. UPHS Health Care: PENN Ob/Gyn Care retinopathy of prematurity (ROP). The Retina The retina is the lightsensitive layer in the back of the interior of the eye. During http://www.pennhealth.com/health/hi_files/pogc/hi/neonatology/retin.html

Neonatal Intensive Care Neonatal Conditions Hyaline Membrane Disease Chronic Lung Disease Necrotizing Enterocolitis Sepsis ... Glossary Medical Services Neonatalogy at Pennsylvania Hospital Neonatalogy at Phoenixville Hospital Neonatology at University of Pennsylvania Medical Center Back to Health Information Retinopathy of Prematurity (ROP) The Retina The retina is the light sensitive layer in the back of the interior of the eye. During gestation, the retina matures slowly, and its blood vessels develop from the very back of the eye toward the outer edge of the retina. By term, the retina is mature, and the blood vessels are in their fully developed positions. ROP When a baby is born prematurely , it is possible that the blood vessels can develop abnormally, a condition called retinopathy of prematurity (ROP). Because ROP can result in visual impairment, all premature infants receive regular eye examinations. The examinations are performed by ophthalmologists from the Children's Hospital of Philadelphia (CHOP) who come to the Pennsylvania Hospital ICN.

80. Retinopathy Of Prematurity In The 1990's Neonatal Network March 1999 Vol. 18, No. 2. retinopathy of prematurityin the 1990's Sharon Lee, RNC, MS, NNP. ABSTRACT. Infants diagnosed http://www.neonatalnetwork.com/nn3/Abstracts/NN0399_4.htm

Neonatal Network March 1999 Vol. 18, No. 2 Retinopathy of Prematurity in the 1990's Sharon Lee, RNC, MS, NNP ABSTRACT Infants diagnosed with retinopathy of prematurity (ROP) are at risk for developing visual impairments. The International Classification of ROP (ICROP) developed the most useful tool available for communicating the location and extent of the condition, with three zones to describe the location and five stages to describe the extent. Despite current knowledge and treatment, however, 500 infants are blinded each year by ROP. Infants at highest risk are the smallest and most immature. The nurse must understand why and how ROP occurs and the forms of management used to treat ROP. This article reports on the incidence, pathophysiology, risk factors, screening, treatment, and long-term complications of ROP in the 1990s.

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