21. Lupus/Systemic Lupus Erythematosus (SLE) Lupus/systemic lupus erythematosus (SLE). systemic lupus erythematosus involveschronic inflammation that can affect many parts of the body, including http://www.arthritis.org/conditions/DiseaseCenter/lupus.asp

Welcome! Log In Create Profile advanced search Español ... 51 Ways to Be Good to Your Joints Lupus/Systemic Lupus Erythematosus (SLE) If your question is not answered here, please contact one of our information specialists. What Is It? What Are the Symptoms? What Causes It? How Is It Diagnosed? ... Resources and Suggestions What Is It? Systemic Lupus Erythematosus (sis-TEM-ick LOO-pus err-ah-theme-ahTOE-sus) is a chronic (long-lasting) rheumatic disease which affects joints, muscles and other parts of the body. Lupus involves inflammation (the immune system's response to kill foreign agents, virus, bacteria). Systemic lupus erythematosus involves chronic inflammation that can affect many parts of the body, including: Heart Lungs Skin Joints Blood-forming organs Kidneys Nervous system There are several types of lupus: Discoid lupus affects the skin. Drug-induced lupus occurs because of a reaction to drugs. Symptoms, however, disappear once the drugs are discontinued. Crossover, or overlap, syndromes indicate features that overlap with another rheumatic disease.

22. Disease Category Listing (144): Systemic Lupus Erythematosus CenterWatch Listing of Clinical Research Trials for systemic lupus erythematosus.Clinical Trials systemic lupus erythematosus. Michigan. http://www.centerwatch.com/patient/studies/cat144.html

Clinical Trials: Systemic Lupus Erythematosus Michigan Ann Arbor; General Clinical Research Center, University of Michigan Clinical and Immunologic effects of mycophenolate mofetil vs. placebo in patients with Systemic Lupus Erythematosus. New York Manhasset; The Program in Novel Therapeutics A placebo-controlled study evaluating the effects of an investigational drug on kidney disease in patients with lupus. Manhasset; The Program in Novel Therapeutics A placebo-controlled study evaluating the effects of an investigational drug on antiphospholipid (anticardiolipin) antibodies in patients with antiphospholipid syndrome. Manhasset; The Program in Novel Therapeutics The pharacoproteomic relationship between anti-DNA antibodies and an investigational drug for systemic lupus erythematosus is being evaluated. Manhasset; The Program in Novel Therapeutics A placebo controlled trial of an investigational therapy in patients with systemic lupus erythematosus. New York; NYU-Hospital for Joint Diseases The National Institute of Arthritis, Musculoskeletal and Skin Diseases and The Hospital for Joint Diseases is currently recruiting patients for serologically active, clinically stable Systemic Lupus Erythematosus. Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials.

23. Antiphospholipid Antibodies And Systemic Lupus Erythematosus Antiphospholipid Antibodies And systemic lupus erythematosus. MichellePetri, MD, MPH Associate Professor of Medicine The Johns Hopkins http://www.hamline.edu/lupus/articles/Antiphospholipid_Antibodies_and_Systemic_L

Antiphospholipid Antibodies And Systemic Lupus Erythematosus Michelle Petri, M.D., M.P.H. Associate Professor of Medicine The Johns Hopkins University School of Medicine Baltimore, MD What are antiphospholipid antibodies? There are several kinds of antiphospholipid antibodies. The most widely measured are the lupus anticoagulant and anticardiolipin antibody. These antibodies react with phospholipid, a type of fat molecule that is part of the normal cell membrane. Lupus anticoagulant and anticardiolipin antibody are closely related, but are not the same antibody. This means that someone can have one and not the other. There are other antiphospholipid antibodies, but they are not commonly measured. How common are antiphospholipid antibodies? As with other autoantibodies (antibodies directed against one's self) in lupus, the antiphospholipid antibodies can come and go in any individual patient. It turns out that there are many ways to measure these antibodies, and different methods may not always give the same result. For example, in different studies, 8 to 65 percent of people with lupus have the lupus anticoagulant, and 25 to 61 percent have anticardiolipin antibody. These antibodies can also be found in people who do not have lupus. For example, two percent of young women have anticardiolipin antibody. These antibodies were first discovered in people who have lupus, but it is not necessary to have lupus to have these antibodies. In fact, in most studies, over 50% of people with these antibodies do not have lupus. We do not understand why a person's immune system begins to manufacture these antibodies.

24. The Eye And Systemic Lupus Erythematosus The Eye and systemic lupus erythematosus. systemic lupus erythematosus is a wide rangingdisease and can affect many organ systems, and the eye is no exception. http://www.hamline.edu/~wnk/lupus/articles/eye.html

The Eye and Systemic Lupus Erythematosus by W Kevin Thomas, M.D. From Lupus Erythematosus, Vol 2, Atlanta Chapter, Lupus Erythematosus Foundation, Inc. Systemic Lupus Erythematosus is a wide ranging disease and can affect many organ systems, and the eye is no exception. Involvement of the eyeball itself is much more common than involvement of the orbit, or socket of the eye. However, when there is involvement of the orbit this is most often manifested by the formation of modules on the conjunctive (the most exterior tissue layer of the eyeball and inner lid). There may also be an accompanying swelling or edema of the lids themselves. The most common observable ocular finding in lupus is the presence of "cotton wool spots" in the retina, or lining of the eye. These "spots" represent areas of the retina which are edematous due to a decreased blood flow, and hence oxygen supply, to certain areas of the retina. Of great importance to both the patient and the doctor is that these changes in the retina will often parallel exacerbations in the general disease state. Although the presence of a "cotton wool spot" is not specific to lupus, the presence of one in a young to middle aged patient should sugest lupus. There are other less common changes which may develop in the retina, and these include the deposition of fat cells in the retina, narrowing the arteriolar blood supply, and occlusion of the main blood vessels to th eye, which could result in a significant loss of visual acuity.

25. Systemic Lupus Erythematosus (SLE) Original feature articles and collections of links written and assembled by a health professional Category Health Conditions and Diseases Connective Tissue Lupus...... systemic lupus erythematosus (SLE) Guide picks. A chronic inflammatoryautoimmune connective tissue disease. ABC's of Lupus Basic http://rarediseases.about.com/cs/lupussle/

zfp=-1 About Rare/Orphan Diseases Search in this topic on About on the Web in Products Web Hosting Rare/Orphan Diseases with Mary Kugler Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects BUYER'S GUIDE Before You Buy Top Picks Sites for Online Specialty Shopping ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Systemic Lupus Erythematosus (SLE) Guide picks A chronic inflammatory autoimmune connective tissue disease. ABC's of Lupus Basic information on lupus to help you get started. General links that describe in fairly easy terms the diagnosis, causes, and treatment for lupus. Children and Lupus Children and adolescents with lupus face a long battle ahead. Children of lupus patients need support also. Complications Lupus is a complex disease. What are some of the complications? Depression Depression resources for patients with lupus. DHEA Lean about the research on this form of the male hormone which does not cure lupus, but may improve quality of life. Diagnosis Learn how to diagnose lupus. Links to sources of information about diagnosing the symptoms of lupus.

26. THE MERCK MANUAL, Sec. 5, Ch. 50, Diffuse Connective Tissue systemic lupus erythematosus. Discoid Lupus Erythematosus. click here for navigationhelp. systemic lupus erythematosus (Disseminated Lupus Erythematosus). http://www.merck.com/pubs/mmanual/section5/chapter50/50e.htm

27. Lupus Erythematosus - About Lupus About lupus. What is lupus? systemic lupus erythematosus, also calledlupus or SLE for short, belongs to the family of rheumatic diseases. http://www.orthop.washington.edu/arthritis/types/lupus

Home About Us Clinics Physicians ... Contact Us Table of contents About lupus What is lupus? Incidence and risk factors Prognosis ... View article with questions External links Lupus Foundation of America [Top] Lupus Erythematosus Edited by Frederick A. Matsen, III, M.D. and Gregory C. Gardner, M.D. Last updated September 4, 2001 About lupus What is lupus? Systemic lupus erythematosus, also called lupus or SLE for short, belongs to the family of rheumatic diseases. Rheumatic diseases affect joints , muscles and other parts of the body, and often involve abnormalities of the immune system. Lupus can affect not only joints and muscles but also skin, kidneys, nervous system, lungs, heart and the blood-forming organs. Lupus is an autoimmune disease in which the tissues of the body are attacked by the overly active immune system and is treated by suppressing the immune system. There are two common forms of lupus: discoid and systemic. Discoid lupus is a disease of the skin which is often chronic and leads to scarring. It may be limited to the skin and not be associated with disease in any other body systems. In other cases, discoid lupus may be one of the features of the systemic form of lupus. This information focuses on the systemic form of the disease. Incidence and risk factors Lupus affects women about eight or 10 times as often as men. In most cases, the symptoms first appear in women of child-bearing age (usually age 18-45). However, lupus can occur in young children or in older people. It occurs more often in blacks and in some Asian and North American Indian groups than in whites.

28. EMedicine - Systemic Lupus Erythematosus : Article By Julie Hildebrand, MD systemic lupus erythematosus systemic lupus erythematosus (SLE) is a chronic, multisysteminflammatory disease that can affect any and every organ system of http://www.emedicine.com/MED/topic2228.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Systemic Lupus Erythematosus Last Updated: July 8, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: SLE, lupus AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Julie Hildebrand, MD , Rheumatology fellow, Department of Internal Medicine, University of Wisconsin Coauthor(s): Daniel Muller, MD, PhD , Associate Professor, Department of Internal Medicine, Section of Rheumatology, University of Wisconsin at Madison Julie Hildebrand, MD, is a member of the following medical societies: American College of Physicians Editor(s): Carlos J Lozada, MD , Director of Rheumatology Fellowship Program, Associate Professor, Department of Medicine, Division of Rheumatology and Immunology, Jackson Memorial Medical Center, University of Miami School of Medicine; Francisco Talavera, PharmD, PhD

29. EMedicine - Systemic Lupus Erythematosus : Article By David W Lamont, DO systemic lupus erythematosus systemic lupus erythematosus (SLE) is an autoimmunedisease involving multiple organ systems that is defined clinically and http://www.emedicine.com/EMERG/topic564.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Emergency Medicine Rheumatology Systemic Lupus Erythematosus Last Updated: December 4, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: SLE AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: David W Lamont, DO , Staff Physician, Emergency Medicine Resident, Department of Emergency Medicine, New York Methodist Hospital Coauthor(s): Mai Kim Lai, MD , Staff Physician, Department of Emergency Medicine, Sparrow Hospital, Michigan State University College of Human Medicine; Steven H Silber, DO, FACEP , Clinical Assistant Professor, Department of Emergency Medicine, Weill Medical College of Cornell University; Vice Chair, Department of Emergency Medicine, New York Methodist Hospital David W Lamont, DO, is a member of the following medical societies: American College of Emergency Physicians American Medical Association American Osteopathic Association Emergency Medicine Residents' Association , and Society for Academic Emergency Medicine Editor(s): Richard S Krause, MD

30. Systemic Lupus Erythematosus - Division Of Maternal Fetal Medicine & Prenatal Di of the condition. SLE isa complex, chronic condition that affects the skin and connective......systemic lupus erythematosus, http://www.dartmouth.edu/~obgyn/mfm/PatientEd/SLE.html

Home Index to Patient Education Amniocentesis Anemia ... Seizure Disorders In Pregnancy Systemic Lupus Erythematosus Sexually Transmitted Diseases Steroids For Fetal Lung Maturity Teen/Adolescent Pregnancy Premature Rupture of Membranes ... top of page Systemic Lupus Erythematosus Description of the condition SLE is a complex, chronic condition that affects the skin and connective tissue, blood, cardiovascular and nervous systems and the kidneys. It is called an autoimmune disease because the immune system, which normally helps destroy foreign invaders, seems to turn against itself and attack healthy tissue in the body. There are certain signs and symptoms that are common to this illness. These signs and symptoms include: generalized discomfort, muscle aches, fatigue, fever, joint inflammation, rash, blood cell changes, sensitivity to sunlight, hair loss, kidney problems, depression and others. Disease Impact on Pregnancy The chances of having a normal pregnancy and favorable delivery are generally good especially if the illness is under good control at the start of pregnancy. Lupus symptoms may improve during pregnancy, but may become more active again after the delivery. Some of the drugs that are used to treat this condition are safe to use during pregnancy, while others can not be used.

31. COR PULMONALE IN SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT AND REVIEW OF THE L Reports a case of SLE who presented with severe pulmonary hypertension and cor pulmonale without any Category Health Conditions and Diseases Cor Pulmonale......May 1995. COR PULMONALE IN systemic lupus erythematosus A CASE REPORT AND REVIEWOF THE LITERATURE. Pulmonary vascular disease in systemic lupus erythematosus. http://www.kfshrc.edu.sa/annals/153/93262.html

May 1995 COR PULMONALE IN SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT AND REVIEW OF THE LITERATURE M. Jawaid Akhtar, MRCP(UK), FRCP(Ire); Sulaiman Al-Majed, FRCP(C) From the Divisions of Cardiology (Dr. Akhtar) and Chest (Dr. Al-Majed), Department of Medicine, King Khalid University Hospital, Riyadh. Address reprint requests and correspondence to Dr. Akhtar: Division of Cardiology, Department of Medicine (38), College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia. Accepted for publication 10 August 1994. Pulmonary hypertension is rare in patients with systemic lupus erythematosus (SLE) although pulmonary involvement occurs in about 50%. Pulmonary hypertension without obvious pulmonary infiltration is even rarer, the mechanism of which is unclear. We report here a case of SLE who presented with severe pulmonary hypertension and cor pulmonale without any evidence of parenchymal lung disease. Case Report The patient was a 19-year-old Saudi female who was admitted to King Khalid University Hospital, Riyadh with a two-year history of dyspnea, easy fatigability, palpitations, anorexia, loss of weight, dry cough and episodic attacks of fever every three to four months with night sweats for the last two years. Five days prior to admission she developed pain in various large and small joints with swelling in interphalangeal and right wrist joints and described features of Raynaud's phenomenon. Chest roentgenogram showed cardiomegaly with prominent pulmonary conus. No lung infiltrate was noticed. High resolution computed tomography (CT) scan was not done. Ultrasound of the abdomen revealed an enlarged liver with mild ascites. Pulmonary function test revealed a restrictive pattern with decreased diffusion lung capacity. Ventilation/perfusion scan of the lungs did not reveal any evidence of pulmonary embolism. Cross-sectional echocardiography and Doppler studies revealed significant enlargement of the right atrium and right ventricle with dilated pulmonary artery and moderate degree of pericardial effusion. Moderate tricuspid incompetence was also detected.

32. Postgraduate Medicine: Systemic Lupus Erythematosus systemic lupus erythematosus. Postgrad Med 1999;106(6)21323. systemic lupus erythematosus(SLE) is frustrating to the medical community and patients alike. http://www.postgradmed.com/issues/1999/11_99/greenberg.htm

Systemic lupus erythematosus Measures to keep this unpredictable disease under control Brent Greenberg, MD; Margaret Michalska, MD VOL 106 / NO 6 / NOVEMBER 1999 / POSTGRADUATE MEDICINE CME learning objectives To recognize common signs and symptoms of SLE To become familiar with criteria established by the American College of Rheumatology as the basis for diagnosis To identify appropriate treatment and preventive measures This page is best viewed with a browser that supports tables Preview : Systemic lupus erythematosus can present in many ways, often mimicking other diseases. In this article, Drs Greenberg and Michalska describe the numerous manifestations of this chronic disease, the widely accepted criteria for diagnosis, and the therapeutic measures that can prolong survival and decrease morbidity. Greenberg B, Michalska M. Systemic lupus erythematosus: measures to keep this unpredictable disease under control. Postgrad Med 1999;106(6):213-23 S ystemic lupus erythematosus (SLE) is frustrating to the medical community and patients alike. The cause of this autoimmune disease is unknown, and nearly all of its clinical features are seen in other diseases as well. Further, the classic malar rash specific to SLE occurs in less than half of SLE patients, and diagnostic tests touted over the past half century have shown crossover with other autoimmune diseases (1). However, certain clinical and laboratory criteria may point strongly to SLE and enable the selection of appropriate treatment. Who is at risk

33. Systemic Lupus Erythematosus systemic lupus erythematosus, Book, Home Page. http://www.fpnotebook.com/RHE17.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Diffuse Assorted Pages Amyloidosis Antiphospholipid Antibody Syndrome Systemic Lupus Erythematosus Polymyalgia Rheumatica ... Medication Causes of Myositis Systemic Lupus Erythematosus Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Diffuse Index Amyloidosis Behcets Syndrome Lupus Anticoagulant Lupus Systemic Polymyalgia Rheumatica Polymyositis Background Polymyositis DDx Polymyositis Evaluation Polymyositis Management Polymyositis Types Idiopathic Scleroderma Sjogren's Etiology Idiopathic Drug Induced Procainamide Isoniazid Hydralazine Minocycline Pathophysiology Tissue damage by antibody and immune complex deposition Symptoms Fatigue Fever Malaise Weight loss Signs Dermatologic Malar "butterfly" rash Photosensitivity Vasculitis Alopecia Oral ulcers Sicca Syndrome Rheumatologic Arthritis Myositis Abdominal Lymphadenopathy Splenomegaly

34. Systemic Lupus Erythematosus (SLE) systemic lupus erythematosus (SLE). thoracic involvement (3070%)lupus pneumonitis (acute) patchy, peripheral, basilar, alveolar; http://chorus.rad.mcw.edu/doc/00855.html

CHORUS Collaborative Hypertext of Radiology Multisystem entities Feedback Search systemic lupus erythematosus (SLE) thoracic involvement (30-70%) lupus pneumonitis (acute): patchy, peripheral, basilar, alveolar interstital reticulation in lower lung fields (chronic) cavitary nodules (vasculitis) pleural changes (most common manifestation): effusion, thickening pericardial effusion (pericarditis) / cardiomegaly (cardiomyopathy) musculoskeletal arthrits (95%): subluxation without erosions AVN ; intrinsically or secondary to steroids kidneys (100%) focal membranous glomerulonephritis aneurysms in interlobar and arcuate arteries (similar to polyarterits nodosa normal/decreased renal size increased parenchymal echogenicity Yong H. Hahn, MD - 2 February 1995 Last updated 14 March 2001 Medical College of Wisconsin

35. InteliHealth: Lupus information. systemic lupus erythematosus (SLE) is most easily recognizedby a occasional rash over the cheeks and bridge of the nose. http://www.intelihealth.com/IH/ihtIH/WSIHW000/9071/8318/201966.html?d=dmtHealthA

36. Systemic Lupus Erythematosus Links, Articles And Topics At Suite101.com - Suite1 start with. or. contains the word(s). Subject Heading systemic lupus erythematosus,Topics (1), Articles (6), BestOf-Web Recommendations (3). Topics. http://www.suite101.com/subjectheadings/contents.cfm/1027

Topics Articles Links BEST OF WEB ONLINE COURSES COMMUNITIES BOOK CIRCLE ... MY SUITE Search Member Central Join Our Community! Login Member Update What's New ... TravelSuite Suite University About Suite University Visit the University Course Listing New Courses ... Featured Courses New Topics Teaching Creative Writing to Children Maine People Organic Vegetable Gardening African-American Home Schooling ... More... Suite Events My Favorite Place War and Peace Spring Into Health! Earth Day 2003 More about Suite101 About Suite101.com Browse Subjects List all subject headings that: start with or contains the word(s) Subject Heading: Systemic lupus erythematosus Topics Articles Best-Of-Web Recommendations Topics Topic: Lupus Editor: Karyn Moran Holton Description: Written by a nurse who is also a lupus patient, this topic provides in... Dewey Code: Articles Title: Discoid Lupus Author: Karyn Moran Holton Description: Discoid lupus is a form of lupus that affects only the skin, not the i... Title: Lupus and African-Americans Author: Karyn Moran Holton Description: African-Americans run a higher risk of developing lupus than do others...

37. Systemic Lupus Erythematosus By keywords Receive HealthLink via email! Subscribe now . systemic lupus erythematosus. Itoccurs in about 20% of patients with systemic lupus erythematosus. http://healthlink.mcw.edu/article/926062834.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Arthritis Skin/Dermatology By keywords: Receive Health Link via email! Subscribe now >> Systemic Lupus Erythematosus Lupus means "wolf." Erythematosus means "redness." In 1851, doctors coined this name for the disease because they thought the facial rash that frequently accompanies lupus looked like the bite of a wolf. Lupus can be categorized into three groups: discoid lupus erythematosus, systemic lupus erythematosus, and drug-induced systemic lupus erythematosus. Discoid lupus erythematosus (DLE) is characterized by a skin rash only. It occurs in about 20% of patients with systemic lupus erythematosus. The lesions are patchy, crusty, sharply defined skin plaques that may scar. These lesions are usually seen on the face or other sun-exposed areas. DLE may cause patchy, bald areas on the scalp and hypopigmentation or hyperpigmentation in older lesions. Biopsy of a lesion will usually confirm the diagnosis. Topical and intralesional corticosteroids are usually effective for localized lesions; antimalarial drugs may be needed for more generalized lesions. DLE only rarely progresses to systemic lupus erythematosus. Systemic lupus erythematosus (SLE, or lupus) is a chronic, inflammatory, multisystem disorder of the immune system. In SLE, the body develops antibodies that react against the person's own normal tissue. This abnormal response leads to the many manifestations of SLE and can be very damaging. The course is unpredictable and individualized; no two patients are alike. Lupus is not contagious, infectious, or malignant. It usually develops in young women of childbearing years, but many men and children also develop lupus. African Americans and Hispanics have a higher frequency of this disease than do Caucasians. SLE also appears in the first-degree relatives of lupus patients more often than it does in the general population, which indicates a strong hereditary component. However, most cases of SLE occur sporadically, indicating that both genetic and environmental factors play a role in the development of the disease.

38. Diseases And Conditions -- Discovery Health -- Systemic Lupus Erythematosus systemic lupus erythematosus, OR SLE, is an autoimmune disorder that affects manyparts of the body. systemic lupus erythematosus By Minot Cleveland, MD. http://health.discovery.com/diseasesandcond/encyclopedia/1787.html

systemic lupus erythematosus By Minot Cleveland, MD Systemic lupus erythematosus, OR SLE, is an autoimmune disorder that affects many parts of the body. An autoimmune disorder is a condition in which the body creates antibodies against its own tissues. What is going on in the body? A person with SLE produces antibodies against many of his or her own tissues. This autoimmune reaction can damage many parts of the body. These include: brain and nervous system digestive system eyes heart joints and muscles kidney lung skin What are the signs and symptoms of the disease? Because SLE affects so many different parts of the body, the disease has many signs and symptoms. These are best listed by organ system. Signs and symptoms that affect the whole body: fatigue fever loss of appetite nausea ... weight loss Signs and symptoms that affect the skin: hives loss of scalp hair red "butterfly rash" on the face, which extends over the cheeks and bridge of the nose in the shape of a butterfly red, raised rashes in areas exposed to the sun sensitivity to the sun ulcers of the mouth, nose, or vagina

39. Health Ency.: Disease: Systemic Lupus Erythematosus Ency. home Disease S systemic lupus erythematosus. systemic lupus erythematosusSee images. Ency. home Disease S systemic lupus erythematosus. http://www.accessatlanta.com/shared/health/adam/ency/article/000435.html

SEARCH: The Web Yellow Pages HOME AJC.COM Illustrated Health Encyclopedia Important notice Ency. home Disease S Systemic lupus erythematosus See images Overview Symptoms Treatment Alternative names: Disseminated lupus erythematosus; SLE; Lupus; Lupus erythematosus Definition: A chronic, inflammatory autoimmune disorder that may affect many organ systems including the skin, joints, and internal organs. Causes and Risks Normally the immune system controls the body's defenses against infection. In systemic lupus erythematosus (SLE) and other autoimmune diseases , these defenses are turned against the body when antibodies are produced against its own cells. These antibodies fight against the body's blood cells, organs, and tissues, causing chronic diseases. The mechanism or cause of autoimmune diseases is not fully known. The disease affects 9 times as many women as men. It may occur at any age, but appears mostly in people between the ages of 10 and 50 years. SLE may also be caused by certain drugs. When this occurs, it is known as drug-induced lupus erythematosus and is usually reversible when the medication is stopped.

40. 1Up Health > Systemic Lupus Erythematosus > Causes, Incidence, And Risk Factors Comprehesive information on systemic lupus erythematosus (Disseminatedlupus erythematosus, Lupus, Lupus erythematosus, SLE). Covers http://www.1uphealth.com/health/systemic_lupus_erythematosus_info.html

1Up Health Systemic lupus erythematosus Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Systemic lupus erythematosus Information Systemic lupus erythematosus Causes, Incidence, and Risk Factors Alternative names : Disseminated lupus erythematosus, Lupus, Lupus erythematosus, SLE Definition : A chronic, inflammatory autoimmune disorder that may affect many organ systems including the skin, joints, and internal organs. Causes, Incidence, and Risk Factors Normally the immune system controls the body's defenses against infection. In systemic lupus erythematosus (SLE) and other autoimmune diseases , these defenses are turned against the body when antibodies are produced against its own cells. These antibodies fight against the body's blood cells, organs, and tissues, causing chronic diseases. The mechanism or cause of autoimmune diseases is not fully known. The disease affects 9 times as many women as men. It may occur at any age, but appears mostly in people between the ages of 10 and 50 years. SLE may also be caused by certain drugs. When this occurs, it is known as drug-induced lupus erythematosus and is usually reversible when the medication is stopped.

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