81. Risk For Valvular Heart Disease Among..., Annals 1 Dec 98 Risk for valvular heart disease among Users of Fenfluramine and DexfenfluramineWho Underwent Echocardiography before Use of Medication. http://www.acponline.org/journals/annals/01dec98/valvhd.htm

Annals of Internal Medicine Current Issue Past Issues Library for Internists Subscriptions ... Email this page Annals of Internal Medicine BRIEF COMMUNICATIONS Risk for Valvular Heart Disease among Users of Fenfluramine and Dexfenfluramine Who Underwent Echocardiography before Use of Medication Annals of Internal Medicine , 1 December 1998. 129:870-874. Christina C. Wee, MD; Russell S. Phillips, MD; Gerard Aurigemma, MD; Stephen Erban, MD, MPH; Gila Kriegel, MD; Marilyn Riley, BS; and Pamela S. Douglas, MD Background: Because uncontrolled echocardiographic surveys suggested that up to 30% to 38% of users of fenfluramine and dexfenfluramine had valvular disease, these drugs were withdrawn from the market. Objective: To determine the risk for new or worsening valvular abnormalities among users of fenfluramine or dexfenfluramine who underwent echocardiography before they began to take these medications. Design: Cohort study. Setting: Academic primary care practices. Patients: 46 patients who used fenfluramine or dexfenfluramine for 14 days or more and had echocardiograms obtained before therapy. Measurements: Follow-up echocardiography. The primary outcome was new or worsening valvulopathy, defined as progression of either aortic or mitral regurgitation by at least one degree of severity and disease that met U.S. Food and Drug Administration criteria (at least mild aortic regurgitation or moderate mitral regurgitation).

82. Valvular Heart Disease valvular heart disease. Anatomy of the human heart. Patients with valvularheart disease have a malfunction of one or more of these valves. http://www.chclibrary.org/micromed/00069920.html

Main Search Index Definition Description Causes ... Resources Valvular heart disease Anatomy of the human heart. The illustration at the bottom right shows how the right and left ventricles contract and relax when blood is pumped through the heart. Definition Valvular heart disease refers to several disorders and diseases of the heart valves, which are the tissue flaps that regulate the flow of blood through the four chambers of the heart. Description The human heart consists of four chamberstwo upper chambers (the atria) and two lower chambers (the ventricles)which are responsible for pumping blood. The heart valves are like one-way doors, which open and close with each beat of the heart, controlling the blood flow from one chamber to the next. Each of these valves is made up of a few thin folds of tissue. When functioning correctly, they keep blood from flowing backwards into a chamber when closed. The four valves function in the following manner: The mitral valve is located between the left atrium and the left ventricle. It is the only valve with two flaps, or cusps. The tricuspid valve is located on the right side of the heart, between the right atrium and right ventricle. It is made up of three cusps, each a different size.

83. Valvular Heart Disease | AHealthyAdvantage You are here Home Health A to Z valvular heart disease. ValvularHeart Disease. Norris, Teresa G. Other valvular heart disease. http://www.ahealthyadvantage.com/topic/topic100587640

Site Search Ills and Conditions Women's Health Men's Health Senior Health ... Self-Care Centers Go To Premera Home Provider Directory Preferred Drug List Cool Tools ... Health A-Z You are here: Home Health A to Z Valvular Heart Disease Valvular Heart Disease Norris, Teresa G. Below: Definition Description Causes and symptoms Diagnosis ... Resources Anatomy of the human heart. The illustration at the bottom right shows how the right and left ventricles contract and relax when blood is pumped through the heart. Definition Valvular heart disease refers to several disorders and diseases of the heart valves, which are the tissue flaps that regulate the flow of blood through the four chambers of the heart. Description The human heart consists of four chamberstwo upper chambers (the atria) and two lower chambers (the ventricles) that are responsible for pumping blood. The heart valves are like one-way doors, which open and close with each beat of the heart, controlling the blood flow from one chamber to the next. Each of these valves is made up of a few thin folds of tissue. When functioning correctly, they keep blood from flowing backwards into a chamber when closed. The four valves function in the following manner: The mitral valve is located between the left atrium and the left ventricle. It is the only valve with two flaps, or cusps.

84. LACA - Services Services Treatments valvular heart disease \ VALVULOPLASTY The heart has fourvalves including the mitral, the aortic, the pulmonic, and the tricuspid. http://www.lacard.com/html/services/valvularheart.html

The heart has four valves including the mitral, the aortic, the pulmonic, and the tricuspid. These valves exist to direct and control blood flow through the heart. Sometimes the valves can become scarred and narrow leading to a need for improving the opening and the blood flow. The most commonly treated valves are the mitral and aortic. We have an ongoing interest and an extensive experience in managing valvular disease. We have achieved a procedural success rate in excess of 95%. We have treated patients ranging from their early teenage years to those in their early 90s. In valvuloplasty, a small balloon is used to dilate the valves resulting in a larger opening and improved blood flow. Other Services: Basic Cardiology - Anatomy and Physiology Electrophysiology Arrhythmias - Types of Arrhythmias - Arrhythmia Treatments ... Treatments for Coronary Artery Disease Interventional Services - Balloon Angioplasty - Stents - Atherectomy ... Peripheral Vascular Disease - Valvular Heart Disease/ Valvuloplasty

85. Valvular Heart Disease Topic valvular heart disease. ACC/AHA guidelines for the managementof patients with valvular heart disease executive summary. http://www.intmed.mcw.edu/ClinicConf/ValveHrtDis.htm

GIM Residents Re: Clinic Conferences: September 4 - 8, 2000 Topic: Valvular Heart Disease Questions Many murmurs in asymptomatic adults are "innocent" and have no functional significance. Describe some of the characteristics of these innocent murmurs. In a patient with a systolic murmur, what physical findings are most useful for ruling in and ruling out aortic stenosis as the cause? Describe the Class I indications for surgery in patients with native valve endocarditis. What factors might influence your decision to recommend surgery to an asymptomatic patient with chronic mitral regurgitation? (see reference # 1 pages 1967-1969) Case scenario An asymptomatic 55 year old man is noted to have a 2/6 early diastolic blowing murmur along the lower left sternal border. A trans-thoracic echocardiogram confirms your diagnosis of aortic insufficiency and demonstrates normal LV systolic function. Describe how you would manage this patient. Specifically, what will you recommend regarding exercise limitations and medical therapy? How often will you see the patient in follow up? What non-invasive parameters will you follow? When would you recommend cardiac catheterization and consideration of valve replacement? References Bonow RO, Carabello B, deLeon AC Jr, et al. ACC/AHA guidelines for the management of patients with valvular heart disease: executive summary. A report of the American College of Cardiolgy/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease.

86. Valvular Heart Disease | BluePrint For Health You are here Home Health A to Z Valvular HeartDisease. valvular heart disease. Norris, Teresa G. http://blueprint.bluecrossmn.com/topic/topic100587640

Search COMPLEMENTARY CARE Acupuncture Massage therapy Fitness centers ... SITE AWARDS You are here: Home Health A to Z Valvular Heart Disease Valvular Heart Disease Norris, Teresa G. Below: Definition Description Causes and symptoms Diagnosis ... Resources Anatomy of the human heart. The illustration at the bottom right shows how the right and left ventricles contract and relax when blood is pumped through the heart. Definition Valvular heart disease refers to several disorders and diseases of the heart valves, which are the tissue flaps that regulate the flow of blood through the four chambers of the heart. Description The human heart consists of four chamberstwo upper chambers (the atria) and two lower chambers (the ventricles) that are responsible for pumping blood. The heart valves are like one-way doors, which open and close with each beat of the heart, controlling the blood flow from one chamber to the next. Each of these valves is made up of a few thin folds of tissue. When functioning correctly, they keep blood from flowing backwards into a chamber when closed. The four valves function in the following manner: The mitral valve is located between the left atrium and the left ventricle. It is the only valve with two flaps, or cusps.

87. Valvular Heart Disease Associated With Commonly Prescribed Diet Pills Title valvular heart disease Associated With Commonly Prescribed Diet PillsURL http//www.pslgroup.com/dg/2E41A.htm Doctor's Guide July 9, 1997. http://www.docguide.com/dg.nsf/PrintPrint/8A2BD63F3D71E3C9852564CF004BEE0B

To print: Select File and then Print from your browser's menu Title: Valvular Heart Disease Associated With Commonly Prescribed Diet Pills URL: http://www.pslgroup.com/dg/2E41A.htm Doctor's Guide July 9, 1997 ROCHESTER, Minn. July 8, 1997 Mayo Clinic today reports a clinical observation of unusual valvular heart disease in 24 patients who had taken the weight-loss medications fenfluramine and phentermine (fen-phen). Last year, doctors wrote a total of 18 million monthly prescriptions for these drugs. "We recommend that patients who are currently taking or considering fen-phen therapy discuss these findings with their physicians, who can help them weigh the benefits and risks of weight reduction therapy," says Dr. Heidi Connolly, Mayo cardiologist and primary author of the paper. "We believe that these cases raise significant concern that this combination of appetite suppressants can have important implications regarding valvular heart disease," she continues, "but more comprehensive study, which we are planning, is needed to make a definitive statement about the association." Physicians identified the patients in this report all women with an average of 43 years during routine medical visits. All 24 patients had cardiovascular symptoms or a heart murmur. Subsequent testing showed that one or more heart valves in each patient was thickened and blood was regurgitating (or "leaking" backwards), making the heart work harder to pump blood throughout the body. Eight of the women had newly documented pulmonary hypertension, a serious and sometimes fatal disease of the heart and lungs. Five patients needed heart surgery to repair or replace damaged valves.

88. Stroke: Valvular Heart Disease Increased The Risk Of Stroke And Death Stroke valvular heart disease increased the risk of stroke and death.Clinical bottom Question. Patient, valvular heart disease. Intervention http://www.eboncall.co.uk/CATs/stroke_Petty_00a.htm

Stroke: valvular heart disease increased the risk of stroke and death Clinical bottom line (level 2b) One in seven patients with valvular heart disease have a cerebrovascular event at 3.5 years. The risk is increased with age atrial fibrillation severe aortic stenosis One in two are dead within 3.5 years. The risk increased with age cerebrovascular events congestive heart failure Petty et al: Stroke 2000; 31 : 2628-2635 Expires November 2003 The study Retrospective cohort study with ?objective ?blinded outcomes, adjusted for confounding factors, not validated in an independent set of patients. Setting: county, USA 729 patients (aged 13 to 107; mean 72, % male) with a moderate-to-severe mitral stenosis (3%), mitral regurgitation (72%), aortic stenosis (19%), aortic regurgitation (15%) or any combination (9%) diagnosed on 2-D echocardiography. Excluded if trivial or mild mitral or aortic stenosis or regurgitation history of cerebrovascular events (stroke, TIA, amaurosis fugax) living in county for 1 year or less Factors studied: age, sex, angina, duration and treatment of valvular heart disease, angina, myocardial infarction, hypertension, congestive heart failure, atrial fibrillation

89. Valvular Hear Disease - Heart In Health And Disease - MIMG Cardiology valvular heart disease. Valvular disease may also lead to heart rhythm disturbances.Valvular disease is quantified and graded as mild, moderate, or severe. http://mimg.com/cardiology/valvular_heart_disease.shtml

Valvular Heart Disease In a normal, healthy heart, the blood flows freely through the valves when they are open but cannot leak through them when the valves are closed. Heart valves can become diseased, however, leading either to improper opening or improper closing of the valve. In some disease states, the normal valve elasticity and compliance is lost over time and the valve becomes stiff, immobile, and unable to open completely, causing an obstruction to the free flow of blood (stenosis). Examples of diseases in which this occurs are mitral valve stenosis ensuing from rheumatic heart disease and aortic stenosis due to calcification and thickening of the aortic valve. Alternatively, valves may close improperly and become leaky (regurgitant). This may occur because the heart has become enlarged or because the valve tissue has become degenerative for various reasons (valve infection, severe mitral valve prolapse, phen-fen use). Both valvular stenosis and regurgitation may cause an audible heart murmur. Typical symptoms of valvular disease consist of shortness of breath and fatique. In severe cases, dizziness or fainting may occur. Valvular disease may also lead to heart rhythm disturbances.

90. NOBEL TIP valvular heart disease, Yazar, Otto, Catherin. Thrombosis in Cardiovascular Disorders,Tough Calls. valvular heart disease, Venous Thromboembolic Disorders. http://www.nobeltip.com/nobeltip.cfm?fuseaction=kitap.detay&ID=895

91. WebHealthCentre.com - Cardiac Corner valvular heart disease. What is valvular heart disease? valvular heart disease isany dysfunction or abnormality of one or more of the heart's four valves. http://www.webhealthcentre.com/general/valvular.asp

Home About Us Feedback Help Cardiac Corner Your Heart Congenital Heart Diseases Septal defects Patent Ductus Arteriosus ... American Heart Month Valvular Heart Disease What is valvular heart disease? What causes valve problems? What are the symptoms of valve diseases? Treatment What is valvular heart disease? Valvular heart disease is any dysfunction or abnormality of one or more of the heart's four valves. The four valves of the heart are: The Tricuspid Valve The tricuspid valve is a flap that lies between the right atrium and the right ventricle. When it opens it allows the impure (de-oxygenated) blood collected in the right atrium to flow into the right ventricle. When the right ventricle contracts it closes and prevents blood from flowing back into the right atrium. Pulmonary Valve The de-oxygenated blood sent out of the right atrium flows into the right ventricle. When the ventricle contracts, the pulmonary valve opens and lets the blood flow out of the heart into the pulmonary artery. The pulmonary artery takes it to the lungs for purification (oxygenation). The Pulmonary valve closes as the ventricles relax, preventing de oxygenated blood from returning to the heart. Mitral Valve The mitral valve is a flap that lies between the left atrium and the left ventricle. The pulmonary vein brings oxygenated blood from the lungs to the left atrium. The mitral valve opens to allow this blood to flowing into the left ventricle. It closes as the left ventricle contracts, preventing blood from flow back into the left atrium; thereby, forcing it to exit through the aortic valve into the aorta.

92. Virtual Hospital: University Of Iowa Family Practice Handbook, Fourth Edition: C University of Iowa Family Practice Handbook, Fourth Edition, Chapter 3. Cardiologyvalvular heart disease. Table 32 summarizes valvular heart disease. http://www.vh.org/adult/provider/familymedicine/FPHandbook/Chapter03/03-3.html

For Providers University of Iowa Family Practice Handbook, Fourth Edition, Chapter 3 Cardiology: Valvular Heart Disease James M. Fox, MD Division of Cardiology, Department of Internal Medicine University of Iowa College of Medicine Peer Review Status: Externally Peer Reviewed by Mosby General. Can present with a spectrum of symptoms based on the valve involved, stenosis or regurgitation, right- or left-sided, and single valve or multivalvular disease. An echocardiogram is critical to the evaluation of a patient with a heart murmur to determine if the murmur is the result of a valve lesion. Table 3-2 summarizes valvular heart disease. Mitral Valve Prolapse (MVP). May result from leaflet billowing, progressive expansion of the mitral annulus, or valve-leaflet myxomatous degeneration. Most patients with MVP are asymptomatic and will have a benign clinical course. Symptoms may include palpitations, fatigue, dyspnea, syncope, atypical chest pain, and episodes of supraventricular tachycardia. However, these symptoms are as common in the general population as in those with MVP and many patients with MVP found incidentally on echocardiography do not have these symptoms.

93. 1.07 Valvular Heart Disease . Damage to heart valves commonly caused by......Essential Drugs List Primary Health Care. 1.07 valvular heart disease.I09.9 http://www.hst.org.za/pubs/edl/phc/1.07.asp

Essential Drugs List Primary Health Care 1.07 Valvular heart disease Description Damage to heart valves commonly caused by rheumatic fever and occasionally by other causes (congenital heart defects, ischaemic heart disease). It may be complicated by: heart failure infective endocarditis atrial fibrillation systemic embolism Management objectives prevent infective endocarditis and heart failure prevent repeated attacks of acute rheumatic fever Non-drug treatment refer all patients with heart murmurs for assessment advise all patients with a heart murmur to inform health care providers of the presence of the heart murmur when reporting for medical or dental treatment Drug treatment administer prophylactic antibiotic treatment prior to certain invasive diagnostic and therapeutic procedures, e.g. tooth extraction, gastroscopy, cystoscopy and any operation to prevent infective endocarditis prophylactic antibiotic therapy for rheumatic fever benzathine penicillin IM, every month children under 30 kg: 600 000 IU children and adults over 30 kg: 1.2 MU

94. Coronary Heart Diseases Virtual Branch Library: Heart Diseases : Valvular Diseas DIAGNOSIS valvular heart disease Recommendations For Investigation And ManagementPractice Guideline (Publication Type) Guideline (Publication Type) This http://wmrlheart.directional.co.uk/scripts/valve.asp

Choose Topic HEART DISEASES • Arrhythmia (available) • Chest Pain (available) • Coronary Disease (available) • Coronary Artery Disease (available) • Heart Failure (available) • Hypertension (available) • Ischaemic Stroke (available) • Myocardial Infarction (available) • Stable Angina (available) • Unstable Angina (available) • Valvular Disease (available) DIAGNOSIS • Coronary Angiography • Electrocardiogram (available) • Nuclear Scanning (available) • Stress test (available) • General (available) • Blood Pressure Lowering (available) • Cardiac Rehabilitation (available) • Dietary Intervention • Lipids Management (available) • Physical Activity • Primary Prevention of Cardiac Events (available) • Smoking Cessation (available) • General (available) • Alcohol Drinking (available) • Diabetes Mellitus • Diet (available) • Family History • Hypertension • Smoking (available) • General (available) DISEASE MANAGEMENT(available) Drug therapies • ACE Inhibitors • Antiarrhythmic Agents • Anticoagulant • Antiplatelet Treatments • Beta-Blockers(available) • Calcium Channel Blockers(available) • Cholestersol Lowering Drugs • Lower Weight Heparin (available) • Nitrates (available) • PTCA (available) • Statins (available) • Thrombolytic Treatment (available) Surgical Procedures • Coronary Artery Bypass Grafts (available) • Revascularisation (available) Medical Interventions • Cardiac Catherisation (available) • Defibrillation (available) • Stents (available) Other • 2nd Prevention of Cardiac events (available) • Cardiac Rehabilitation (available) • General (available)

95. Missing Page : St. Jude Medical Information on how heart valves work, heart sounds, and types and causes of valvular disease. http://www.sjm.com/4.0/4.2/4.2.1.shtm

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96. Mitral Valve Prolapse Education And Support Learn about MVP, its symptoms, arrhythmias, chest pain, heart sounds, regurgitation, endocarditis, heart failure, valvular disease and other related topics. An email group for support and regular newsletters is available. http://mitral-valves.faithweb.com

Free Web site hosting - Freeservers.com advertisement MITRAL VALVE PROLAPSE ABOUT ME: My name is Paula and I am 47 years old. I found out in 1995 that I have Mitral Valve Prolapse and this led me to further investigation of this disease. WHY I AM HERE I would like to share what I have learned about MVP. Just click below on the page of interest and it will take you there. Join my email group at eGroups for learning, sharing and support with others who have MVP. If you have feedback or suggestion please email me and please remember to sign my guest book. Enjoy your visit!! NOTE: As with any information presented to you, use your discernment when visiting this site. Before taking any supplements or changing your life style, contact your health care provider. All information sent to me in email form or other means of communication, other than by way of my guest book, will be held in the strictest of confidence. Information posted in my guest book can be seen by all visitor. This site has been completely funded by myself and hosted for free by Freeservers. The banner at the top of each page is advertising for Freeservers and my "price" for having my site with them.

97. Heart Disease The Mayo Clinic reported on July 8, 1997 a clinical observation of unusual valvularheart disease in 24 patiënts who had taken the weightloss medications http://www.health.fgov.be/AGP/fr/articles/messages/effets_secondaires/heart-dise

Présentation Législation Professions Manpower ... Diabète Info patient Sang/Organes Heart Disease Valvulvar heart disease associated with commonly rescribed diet pills The Mayo Clinic reported on July 8, 1997 a clinical observation of unusual valvular heart disease in 24 patiënts who had taken the weight-loss medications fenfluramine and phentermine (fen-phen). Last year, doctors wrote a total of 18 million monthly prescriptions for these drugs. "We recommend that patients who are currently taking or considering fen-phen therapy discuss these findings with their physicians, who can help them weigh the benefits and risks of weight reduction therapy", said Dr. Heidi Connolly, Mayo cardiologist and primary author of the paper. "We believe that these cases raise significant concern that this combination of appetite suppressants can have important implications regarding valvular heart disease," she continued,"but more comprehensive study, which we are planning, is needed to make a definitive statement about the association." Physicians identified the patients in this report-all women with an average of 43 years- during routine medical visists. All 24 patients have cardiovascular symptoms or a heart murmur. Subsequent testing showed that one or more heart valves in eacht patient was thickened and blood was regurgitating (or "leaking" backwards), making the heart work harder to pump blood throughout the body. Eight of the women had newly documented pulmonary hypertension, a serious and sometimes fatal disease of the heart and lungs. Five patients needed heart surgery to repair or replace damaged valves. No patients in the report have died to date.

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