NINDS Mobius Syndrome Information Page Also known as congenital facial diplegia, an information sheet compiled by NINDS.Category Health Conditions and Diseases Mobius SyndromeMobius Syndrome (congenital facial diplegia) information sheet compiled bythe National Institute of Neurological Disorders and Stroke (NINDS). http://www.ninds.nih.gov/health_and_medical/disorders/mobius.htm
Extractions: There is no specific course of treatment for Mobius syndrome. Treatment is supportive and symptomatic. Infants may require feeding tubes or special bottles to maintain sufficient nutrition. Surgery may correct strabismus and improve limb and jaw deformities. Physical and speech therapy may improve motor skills and coordination, and help to better control speaking and eating abilities. Plastic reconstructive surgery may be beneficial in some individuals. Also, in a few cases, nerve and muscle transfers (microvascular muscle transplant) to the corners of the mouth have been performed to provide some ability to smile. What is the prognosis?
Facial Nerve Department of Neurology at this medical school offers anatomy and diagnosis information for facial paralysis conditions like Bell's palsy. Follow a diagnosis outline. l MBS1 Chromosome 13q12.2q13; Dominant , or. Clinical. congenital facial diplegia; ± Asymmetric http://www.neuro.wustl.edu/neuromuscular/nanatomy/vii.htm
Extractions: Widened palpebral fissure Signs Stapedius dysfunction (33%): Hyperacusis Lacrimation: mildly affected in some patients Taste: No clinically significant changes in most patients Prognosis better Course Treatment of Bell's palsy Corticosteroids within one week of onset Prednisone 80 mg qd x 5 days; then taper over 1 week
The Congenital Facial Diplegia Syndrome Clinical Features, Pathology The congenital facial diplegia syndrome clinical features, pathology and aetiology Pages 381 403 Part of the OUP Brain WWW service Click here to register with OUP. Last updated 13 May 97 http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_62/Issue_04/620381.sgm.
Möbius' Syndrome II (www.whonamedit.com) Möbius' syndrome II A very rare syndrome characterized by congenital palsy of the external rectus and facial muscles, usually bilateral, associated with paralysis of the sixth and seventh nerves. Also known as Möbius anomalad. abducensfacial paralysis; congenital bulbar paralysis; congenital facial diplegia; congenital facial paralysis; congenital http://www.whonamedit.com/synd.cfm/52.html
Extractions: Akinesia algera; arthrogryposis; congenital abducens-facial paralysis; congenital bulbar paralysis; congenital facial diplegia; congenital facial paralysis; congenital nuclear agenesis; congenital nuclear aplasia; congenital occulofacial paralysis; congenital paralysis of the sixth and seventh nerves; infantile nuclear aplasia; nuclear agenesis syndrome; oculofacial paralysis syndrome; In this very rare syndrome, the abducens and facial nerves, which originate in the brain stem, may not develop from birth. It is characterized by congenital palsy of the external rectus and facial muscles, usually bilateral, associated with paralysis of the sixth and seventh nerves. The patient has a masklike expression and is unable to abduct the eyes beyond midpoint. Involvement of the jaw may cause feeding problems. The disorder may have a number of different causes, one author ascribes it to aplasia of the nuclei of the abducens and facial nerves. According to one author it was first described by von Graefe in 1880. However, ince Albrecht von Graefe died in 1870, this probably refers to the textbook by Alfred Graefe and Edwin Theodor Saemisch. It was described by Möbius in 1888 and again in 1892 when he reported 44 cases and applied the term «nuclear atrophy.»
NINDS - News And Events Chronic Pain Coffin Lowry Syndrome Coma, including Persistent Vegetative State ComplexRegional Pain Syndrome congenital facial diplegia Congenital Vascular http://www.ninds.nih.gov/health_and_medical/news.htm
Extractions: The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only they do not constitute endorsements of those other sites. Home Contact Us Privacy Links Directory
Moebius Syndrome (Congenital Facial Diplegia) HOME Moebius Syndrome/Sequence (congenital facial diplegia). MOBIUSSYNDROME; congenital facial diplegia; SINDROME DI MOEBIUS. HOME http://www.bdid.com/moebius.htm
Result Of Search 1;p;34? MOEBIUS SYNDROME (congenital facial diplegia) 1;p;3436 HYPOPHOSPHATASIA1;p;36 EHLERS-DANLOS SYNDROME TYPE VI 9;p;21 1;p;36? DYSPLASTIC NEVUS SYNDROME. http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-id-look2.pl?1 p
ClinicalTrials.gov - Linking Patients To Medical Research Search Query Details. No studies were found for congenital facial diplegia ALLFIELDS.Modify Your Search. Individual Terms, Count. congenital facial diplegia , None. http://www.clinicaltrials.gov/search/term=Congenital Facial Diplegia
NINDS Mobius Syndrome Information Page Mobius Syndrome (congenital facial diplegia) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). Synonym(s) congenital facial diplegia. Reviewed 0701-2001 http://accessible.ninds.nih.gov/health_and_medical/disorders/mobius.htm
Extractions: Disorders - National Institute of Neurological Disorders and Stroke (NINDS) Skip menus Home About NINDS Disorders-you are in this section ... Find People The nation's leading supporter of biomedical research on disorders of the brain and nervous system. Select Topic Disorder Quick Links Alzheimer's Autism Cerebral Palsy Chronic Pain Epilepsy Headache Multiple Sclerosis Parkinson's Stroke Traumatic Brain Injury Studies with patients Research literature Press release NINDS Search (search help) Contact us My privacy NINDS is part of the National Institutes of Health Contact us NINDS Mobius Syndrome Information Page
Extractions: The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only they do not constitute endorsements of those other sites. Home Contact Us Privacy Links Directory
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: congenital facial diplegia, congenital nuclear agenesis, congenital nuclear hypoplasia, congenital oculofacial paralysis Background: Möbius syndrome is due, in part, to loss of function of motor cranial nerves. Although von Graefe described a case of congenital facial diplegia in 1880, the syndrome was reviewed and defined further by Möbius in 1888 and 1892. Because of these contributions, Möbius is now the eponym used to describe the syndrome. The definition and diagnostic criteria for Möbius syndrome vary among authors. Both von Graefe and Möbius accepted only cases with both congenital facial diplegia and bilateral abducens nerve palsies as constituting Möbius syndrome. In 1939, Henderson broadened the definition and included cases with congenital unilateral facial palsy. Other authors are more restrictive in attempts to eliminate conditions of a different pathogenesis being labeled as Möbius syndrome. These investigators require the presence of a congenital musculoskeletal anomaly in order to make the diagnosis. Pathophysiology: The complete pathophysiological description of Möbius syndrome remains elusive. Whether nerve, brainstem, or muscle aplasia is the primary event has not been established. Nerves that may be involved include cranial nerves (CN) VI through XII, with general sparing of CN VIII. CN III and CN IV can be involved, but rarely are. The facial nerves (CN VII) are involved in all cases, the abducens nerves (CN VI) in a high percentage of cases (75%), and the hypoglossal nerves (CN XII) in only a minority of cases.
Sues: Volume 62: January - December 1939: Issue 4: December 1939 GF . Rowbotham Pages 364 380. The congenital facial diplegia syndrome clinicalfeatures, pathology and aetiology. JL . Henderson Pages 381 - 403. http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_62/Issue_04/
Extractions: GL Brown and AM Harvey Pages: GF Rowbotham Pages: JL Henderson Pages: MB Bender and MG Kanzer Pages: JN Cumings and O Maas Pages: AM Stewart-Wallace Pages: Part of the OUP Brain WWW service Click here to register with OUP. This page is maintained by OUP admin Last updated 13 May 97 Part of the OUP Journals World Wide Web service Oxford University Press, 1997
Service Page - Pathologie Information DISEASE Moebius syndrome, Synonym(s) congenital facial diplegia,CIM Q87.0, Moebius syndrome is a rare developmental disorder from http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=570
ORPHANET® : Moebius Syndrome Translate this page ORPHANET. ORPHANET database access. Moebius syndrome. Direct accessto details Alias congenital facial diplegia. Home Page. http://www.orpha.net/static/GB/moebius.html
Síndrome De Mobius Unilateral Translate this page Mobius syndrome The congenital facial diplegia syndrome. Arch Dis Childh. The congenitalFacial diplegia syndrome clinical features, pathology and ethiology. http://www.encolombia.com/otorrino28200-sindrome.htm
Extractions: María Fernanda Aragón****, MD. Profesor Asociado Universidad Militar Nueva Granada. Servicio de Otorrinolaringología, Grupo de Otología-Neurotología. Hospital Militar Central. Santafé de Bogotá, Colombia. Profesor Universidad Militar Nueva Granada. Jefe del Servicio de Otorrinolaringología, Grupo de Otología-Neurotología. Hospital Militar Central. Santafé de Bogotá, Colombia. Residente Tercer Nivel Universidad Militar Nueva Granada. Servicio de Otorrinolaringología. Hospital Militar Central. Santafé de Bogotá, Colombia. Residente Segundo Nivel Universidad Militar Nueva Granada. Servicio de Otorrinolaringología. Hospital Militar Central. Santafé de Bogotá, Colombia. RESUMEN El síndrome de Mobius es una entidad caracterizada por parálisis del VI y VII par, pudiendo existir compromiso de otros pares craneanos o asociación a alteraciones de la pared torácica, retardo mental y alteraciones de las extremidades. Normalmente es de presentación bilateral, pero puede presentarse en forma unilateral. El presente reporte muestra el caso de una paciente de 15 años de edad quién consulta por presentar parálisis facial congénita unilateral y VI par ipsilateral; siendo estas sus únicas manifestaciones clínicas.
