Extractions: Health-Nexus.Net Health-Nexus.Org The #1 Health information site Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Crigler-Najjar Syndrome MEDLINEplus Medical Encyclopedia: Crigler-Najjar syndrome Crigler-Najjar syndrome. ... Causes and risks Return to top. Crigler-Najjar syndrome is inherited as an autosomal recessive trait. Parents ...
GILBERT SYNDROME 1. Genetic. 1. criglernajjar syndrome-Type I. 2. Gilbert Syndrome (Crigler-NajjarSyndrome-Type II). mild-moderate inherited deficiency of enzyme activity. http://www.icondata.com/health/pedbase/files/GILBERTS.HTM
Crigler-Najjar Syndrome criglernajjar syndrome. Definition Causes, incidence, and risk factorscrigler-najjar syndrome is inherited as an autosomal recessive trait. http://www.pennhealth.com/ency/article/001127.htm
Extractions: Disease Injury Nutrition Poison ... Prevention Definition: Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ malfunctions. Causes, incidence, and risk factors: Crigler-Najjar syndrome is caused by an abnormal gene which fails to produce a functional enzyme (bilirubin glucuronyltransferase) capable of converting bilirubin into a water-soluble and therefore, easily excreted form. As a result, bilirubin can build up in the body, which can damage the brain and other organs. The syndrome is inherited as an autosomal recessive trait. This means that the child must get the defective gene from both parents to develop the severe form of the condition. Parents who are carriers (with just one defective gene) have about half the normal enzyme activity of a normal adult. Infants who inherit the trait from both parents (this is called homozygous for the abnormal gene) develop severe jaundice (hyperbilirubinemia) beginning a few days after birth. If these infants are not treated, they may develop
Crigler-Najjar Syndrome criglernajjar syndrome. Alternative Names Glucuronyl transferase deficiency Afamily history of crigler-najjar syndrome. Review Date 8 http://www.pennhealth.com/ency/article/001127sym.htm
Crigler-Najjar Syndrome : Meddie Health Search ITEMS LINKS Austin Health Information An overview of criglernajjarsyndrome including symptoms, treatment and prevention. (Rating http://www.meddie.com/search/Health/Conditions_and_Diseases/Genetic_Disorders/Cr
Avera Health - Crigler-Najjar Syndrome criglernajjar syndrome. Definition Prevention Genetic counseling is recommendedfor prospective parents with a family history of crigler-najjar syndrome. http://www.avera.org/adam/ency/article/001127.htm
Extractions: Disease Injury Nutrition Poison ... Liver anatomy Definition: Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ malfunctions. Causes, incidence, and risk factors: Crigler-Najjar syndrome is caused by an abnormal gene which fails to produce a functional enzyme (bilirubin glucuronyltransferase) capable of converting bilirubin into a water-soluble and therefore, easily excreted form. As a result, bilirubin can build up in the body, which can damage the brain and other organs. The syndrome is inherited as an autosomal recessive trait. This means that the child must get the defective gene from both parents to develop the severe form of the condition. Parents who are carriers (with just one defective gene) have about half the normal enzyme activity of a normal adult. Infants who inherit the trait from both parents (this is called homozygous for the abnormal gene) develop severe jaundice (hyperbilirubinemia) beginning a few days after birth. If these infants are not treated, they may develop
CRIGLER-NAJJAR SYNDROME criglernajjar syndrome - A rare genetic defect (autosomal recessive) where thereis the inability to form bilirubin glucuronide due to the absence of the http://www.medhelp.org/glossary/new/gls_1354.htm
CRIGLER-NAJJAR SYNDROME criglernajjar syndrome - A rare, autosomal recessive cause of nonhemolyticjaundice. The problem stems from a genetic defect where http://www.medhelp.org/glossary2/new/gls_1466.htm
Extractions: CRIGLER-NAJJAR SYNDROME - A rare, autosomal recessive cause of nonhemolytic jaundice . The problem stems from a genetic defect where there is the inability to form bilirubin glucuronide due to the absence of the enzyme bilirubin-glucuronoside glucuronosyltransferase. Characteristics include the signs and symptoms of jaundice with irreversible brain damage in the most severe form of the disease. Treatments include phototherapy, exchange transfusions, and cholestyramine.
Crigler-Najjar3bis Clinical description of the criglernajjar syndrome from the Online Mendelian Inheritancein Man database. NORD. Mutations in crigler-najjar syndrome patients. http://it.geocities.com/criglernajjar/trebis.htm
Extractions: SYNDROME Please refer to the following link: Crigler-Najjar Web pages Other useful links: OMIN Clinical description of the Crigler-Najjar syndrome from the Online Mendelian Inheritance in Man database. NORD Clinical description of the Crigler-Najjar syndrome from the National Organization for Rare Disorders, Inc. database. Dr. Namita Roy-Chowdhury Home page of Dr. N. Roy-Chowdhury at the Albert Einstein College of Medicine of Yeshiva University, Bronx, NY. The Human Gene Mutation Database Mutations in Crigler-Najjar syndrome patients. B-UDPGT Human UDP-glucuronosyltransferase from the OMIN database. Online Medical Dictionary Medical dictionary from the CancerWeb. Yahoo.health Clinical description of the Crigler-Najjar syndrome from the database of Adam.com. Yahoo.health. Glossary of Genetic Terms Glossary of genetic term from the NIH site. Cholestyramine Information on cholestyramine frome On Health web site. Download Acrobat file data sheet of Questran. Gabriella's Crigler-Najjar Page Personal page of a Crigler-Najjar patient. More Liver Links Foundations: American Liver Foundation Children's Liver Disease Foundation Center for Liver Disease and Transplantation Children's Liver Alliance Inc. (Australia)
Crigler-Najjar3registry Web Page http//www.criglernajjar.com. THE criglernajjar syndrome GROUP. THE CRIGLER-NAJJARSYNDROME NEWSLETTER. Newsletter made by Crigler-Najjar families. http://it.geocities.com/criglernajjar/treregistry.htm
Extractions: SYNDROME THE CRIGLER NAJJAR ASSOCIATION CNA / Kings Way Foundation c/o Cory Mauck 3134 Bayberry Street Witchita, Kansas 67226 e-mail: mauckc@msn.com THE CRIGLER-NAJJAR SYNDROME GROUP List of parents, patients and healthcare providers, sharing common experiences about Crigler-Najjar syndrome type I and II. GO TO THE CRIGLER-NAJJAR GROUP Newsletter made by Crigler-Najjar families. It is a way to stay connected with other Crigler-Najjar families. If you would like to receive a copy or send a story about your experience with Crigler-Najjar syndrome, please contact the Hiscock family at the following address: hiscock@optonline.net
Crigler-Najjar Syndrome Information Page Diseases Database criglernajjar syndrome Information Page. 2 synonyms or equivalents were found.crigler-najjar syndrome aka/or Glucuronyl transferase deficiency http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=3176
Extractions: Health-Nexus.Com Health-Nexus.Net The #1 Health information site Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Crigler-Najjar Syndrome MEDLINEplus Medical Encyclopedia: Crigler-Najjar syndrome Crigler-Najjar syndrome. ... Causes and risks Return to top. Crigler-Najjar syndrome is inherited as an autosomal recessive trait. Parents ...
ORPHANET® : Crigler-Najjar Syndrome Translate this page ORPHANET database access. crigler-najjar syndrome. Direct access to details Alias Bilirubin uridinediphosphate glucuronosyltransferase deficiency. Home Page. http://www.orpha.net/static/GB/crigler_najjar.html
Service Page - Pathologie Information DISEASE criglernajjar syndrome, Synonym(s) Bilirubin uridinediphosphateglucuronosyltransferase deficiency, CIM E80.5, Crigler http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=205
Crigler-Najjar Syndrome criglernajjar syndrome. BASICS DESCRIPTION Two distinct, inherited,syndromes marked by deficiencies of hepatic glucuronyl transferase. http://www.5mcc.com/Assets/SUMMARY/0237.html
Maladie De Gilbert Et Maladie De Crigler-Najjar Translate this page regions of human bilirubin-UDP-glucuronosyltransferase gene complex and identificationof a genetic mutation in a patient with crigler-najjar syndrome, type I http://www.hepatoweb.com/hepatobase/bilirubine.html
Extractions: 1. Arias IM, Gartner LM, Cohen M, Ben Ezzer J. Chronic non-hemolytic unconjugated hyperbilirubinemia with glucuronosyltransferase deficiency. Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity. Am J Med 2. Crigler JF, Najjar VA. Congenital familial non-hemolytic jaundice with kernicterus. Pediatrics 3. Burchell B, Coughtrie MWH, Jansen PLM. Function and regulation of UDP-glucuronosyltransferase genes in health and liver disease : report of the 7th international workshop on glucuronidation, september 1993, Pitlochry, Scotland.
Crigler-Najjar Syndrome - General Practice Notebook criglernajjar syndrome. crigler-najjar syndrome is a rare form of congenitalnon-haemolytic hyperbilirubinaemia. Type I Crigler-Najjar http://www.gpnotebook.co.uk/cache/349175813.htm
Extractions: Crigler-Najjar syndrome Crigler-Najjar syndrome is a rare form of congenital non-haemolytic hyperbilirubinaemia. Type I Crigler-Najjar syndrome is characterised by a total deficiency of hepatic glucuronyl transferase. It is inherited as an autosomal recessive. Conjugated bilirubin is absent from the serum. The majority die with kernicterus in the first year of life. Phototherapy can reduce the serum bilirubin by 50% and may be performed at home. Type II Crigler-Najjar syndrome is characterised by a partial deficiency of glucuronyl transferase. It is inherited as an autosomal dominant. Patients given phenobarbital often survive into adult life. Phototherapy may be used to lower the serum bilirubin level.
Home criglernajjar syndrome is caused by a liver enzyme deficiency. The Crigler-NajjarAssociation. In Search of a Cure for crigler-najjar syndrome. http://www.criglernajjar.com/
Extractions: Crigler-Najjar Syndrome is caused by a liver enzyme deficiency Crigler-Najjar Syndrome (CNS) is an inherited metabolic disorder caused by a liver enzyme deficiency which prevents the usual metabolic breakdown of bilirubin; a normal by-product in our bodys disposal of worn-out red blood cells. Children with CNS are unable to eliminate bilirubin from their bodies and therefore must undergo daily 12-hour exposure to special blue lights, just to survive. Without daily treatments, a child would suffer brain damage, muscle and nerve damage and death due to bilirubin toxicity. A Rare Orphan Disease Crigler-Najjar is a very rare disease. There are less than 50 known cases in the USA, and less than 200 worldwide. It is named after Dr. Crigler and Dr. Najjar who discovered the disease. Dr. John F. Crigler is a Special Medical Two-year-old Melanie has to sleep under intense blue lights to help combat the disease Crigler-Najjar Syndrome Advisor to the CNA. The Crigler-Najjar Association In Search of a Cure for Crigler-Najjar Syndrome Our group represents approximately 50 families in the U.S.A. who have family members affected by Crigler-Najjar syndrome. Started in 2002 with a handful of Crigler-Najjar families, our group has grown and expanded to represent all families who are interested in finding a cure, and helping others who are less fortunate.
