Geometry.Net - Health_Conditions: Epstein-barr Virus

Epstein-Barr Virus Causes Nasopharyngeal Cancer And Lymphomas
epsteinbarr virus Causes Nasopharyngeal Cancer and Lymphomas. EBV Various Cancers. TheNational Cancer Institute's Evasion of the Role of epstein-barr virus.
http://ourworld.compuserve.com/homepages/CarolASThompson/EBV.htm

Extractions: In addition to its original linkages with Burkitt's lymphoma and infectious mononucleosis, Epstein-Barr virus is now believed to be the cause of nasopharyngeal cancer, T-cell lymphoma, natural killer (NK) cell lymphoma, Hodgkin's disease and gastric carcinoma. As usual, the anti-smokers ignore the role of this virus in order to falsely blame smoking and passive smoking. "Evaluation. There is sufficient evidence for the carcinogenicity of EBV in the causation of Burkitt's lymphoma, sinonasal angiocentric T-cell lymphoma, immunosuppression-related lymphoma, Hodgkin's disease and nasopharyngeal carcinoma." "EBV is carcinogenic to humans (Group I)."
HealthlinkUSA Epstein-Barr Virus Links
medical and health related topics. FindWhat. Click here for page 1 ofepsteinbarr virus information from the HealthlinkUSA directory.
http://www.healthlinkusa.com/388ent.htm
CyberSpace Search!
SEARCH THE WEB. Results 1 through 10 of 16 for epsteinbarr virus.
http://www.cyberspace.com/cgi-bin/cs_search.cgi?Terms=epstein-barr virus
Research On Station---Reactivation Of Latent Epstein-Barr Virus
Space FlightInduced Reactivation of Latent epstein-barr virus (Epstein-Barr)Principal Investigators Raymond Stow and Alan Barrett, University of Texas
http://spaceresearch.nasa.gov/research_projects/ros/eb.html
Research On Station---Reactivation Of Latent Epstein-Barr Virus Results
Space FlightInduced Reactivation of Latent epstein-barr virus (Epstein-Barr) Results. 2000.Stress-induced reactivation of epstein-barr virus in astronauts.
http://spaceresearch.nasa.gov/research_projects/ros/ebresults.html

Extractions: Epstein-Barr is just one of several flight experiments that has monitored the reactivation of latent viruses during space flight. The stresses of space flight can also reactivate viruses such as herpes simplex-1 (a virus related to Epstein-Barr and chicken pox), which most commonly causes sores around the mouth, nose, chin, and cheek, but can also cause pharyngitis and tonsillitis. Detailed Supplementary Objective (DSO) research focusing solely on Epstein-Barr virus reactivation began during STS-108 (December 2001). The Expedition 5 crew will be the first participants to provide information on virus reactivation during long-duration space flight. Earlier research by the Epstein-Barr researchers (see R.P. Stowe et al, 2000; 2001) indicated that physical and psychological stress, measured through stress hormones present in postflight urine samples, resulted in decreased virus-specific T-cell immunity and reactivation of Epstein-Barr virus (EBV) in Shuttle astronauts. Their findings also have shown that reactivation begins, due to stress, before flight and acute lytic replication occurs during flight. These findings are the basis of the current investigation. Applications EBV was first discovered as part of research into a cancer, later called Burkitt's Lymphoma, found in children from Africa. EBV, however, is one of the most common human viruses, affecting people worldwide. Although it frequently remains latent throughout the carrier's lifetime, it can be reactivated, causing moderate to severe illnesses and long-term, life-threatening complications. People with compromised immune systems, such as organ transfer and AIDS patients, run a particular risk of the virus becoming active. Stress can also reactivate it.
Epstein-Barr Virus Linked To Invasive Breast Cancer And Lymphoma
News Releases epsteinbarr virus linked to invasive breast cancer and lymphoma.UM scientists find virus releases molecular brake on roaming cancer cells.
http://www.cancer.med.umich.edu/news/virus.htm

Extractions: Epstein-Barr virus linked to invasive breast cancer and lymphoma U-M scientists find virus releases molecular brake on roaming cancer cells ANN ARBOR, MI Scientists in the University of Michigan Medical School have found a molecular link between aggressive breast and lymphatic cancers and the Epstein-Barr virus, which causes infectious mononucleosis. In a paper published in the March 2001 issue of Nature Medicine, U-M scientists show how the Epstein-Barr virus alters the function of a cellular protein that normally suppresses the movement of malignant cells. When this natural brake on cell migration is disabled by the virus, cancerous breast and lymphatic cells are free to metastasize or spread. "This is the first evidence of a human virus associated with the development of cancerous tumors targeting a cellular protein to promote the migration of malignant cells," says Erle S. Robertson, Ph.D., who directed the study. Robertson is an assistant professor of microbiology and immunology in the U-M Medical School and a researcher in the U-M's Comprehensive Cancer Center. "The Epstein-Barr virus is associated with many human cancers including Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's disease and invasive breast cancer," Robertson says.
Epstein-Barr Virus
Primary infection of epsteinbarr virus (EBV), which is primarily transmitted bysaliva, actively replicates in the epithelial cells of the oropharynx and can
http://www.uq.edu.au/vdu/EBV.htm

Extractions: - EBV shown to immortalize lymphocytes in culture; EBV can immortalize marmoset cells and cause tumors in non-human primates. Primary infection of Epstein-Barr virus (EBV), which is primarily transmitted by saliva, actively replicates in the epithelial cells of the oropharynx and can subsequently infect recirculating B lymphocytes which may lead to acute infectious mononucleosis (glandular fever). Infectious mononucleosis is a benign lymphoproliferative disease that is usually seen in children, although most cases of EBV infection occur in early childhood and have no symptoms. It is characterised by transient immunosuppression and an unusual expansion of atypical lymphocytes, the majority of which are not B cells but CD8
Epstein-Barr Virus - Treatment And Information
epsteinbarr virus. epstein-barr virus (EBV) is a condition that has becomewidespread in the USA. The causes of epstein barr is not well understood.
http://www.go-symmetry.com/health/epstein-barr.htm

Extractions: Epstein-Barr Virus Epstein-Barr virus (EBV) is a condition that has become widespread in the USA. The causes of epstein barr is not well understood. Some experts believe it is associated with chronic fatigue syndrome (CFS) based on the fact a lot of people with chronic fatigue syndrome have high level of EBV antibodies in their blood. Intestinal parasites are also common with people who have chronic fatigue syndrome . Epstein-Barr can reoccur at any time especially after illness or stress Nutrient / Supplement Importance Helpful notes Essential fatty acids helps strengthen your body's immune system which is weaken by Epstein-Barr. Fatty acids are found in omega fatty acids from fish oil, flax seed oil, and borage seed oil. Acidophilus replaces needed bacteria that are helpful to your digestion and also helps fight candida infection. Sometimes found is a vitamin and herbal blend. contains vitamin E, vitamin B , vitamin C, magnesium, manganese, selenium, potassium, and zinc which all are helpful in both the treatment and prevention of Epstein-Barr as well as general good health and well being.
EBV Antigen (Epstein-Barr Virus)
epsteinbarr virus (EBV) Infected Cell Extract. Epstein-BarrVirus (EBV) gp125 Viral Capsid Antigen (VCA).
http://www.virusys.com/Antigens/Epstein-Barr_Virus_Antigen/epstein-barr_virus_an
EBV (Epstein-Barr Virus) Antibodies
epsteinbarr virus (EBV) Monoclonal Antibodies. Links open in a separate window
http://www.virusys.com/Antibodies/Epstein-Barr_Virus_Antibody/epstein-barr_virus
High Levels Of Epstein-Barr Virus Antibodies In Women Linked To Risk Of Multiple
High Levels of epsteinbarr virus Antibodies in Women Linked to Risk of MultipleSclerosis For immediate release Wednesday, December 26, 2001.
http://www.hsph.harvard.edu/press/releases/press12262001.html

Extractions: Boston, MA Researchers from the Harvard School of Public Health have found that elevated levels of specific antibodies that fight a range of Epstein-Barr Virus (EBV) antigens are associated with the onset of multiple sclerosis (MS). The study results appear in the December 26, 2001 issue of the Journal of the American Medical Association (www.jama.com). Blood samples from more than 62,000 women were collected between 1989 and 1999. The researchers documented 144 cases of MS including 18 cases with blood samples collected before the onset of the disease. For each woman with MS, two without MS, who were the same age were randomly chosen as controls. Compared to their controls, the women with MS had significantly higher average blood levels of antibodies for EBV antigens before the onset of the disease. The strongest association was found for antibodies for Epstein-Barr Nuclear Antigen-2 (EBNA-2). These levels increase soon after EBV infection but normally decline within a few months. In this study, elevated levels of EBNA-2 antibodies were associated with a four-fold increase in risk of MS.
HK University Theses Online
Title epsteinbarr virus characteristics and its correlation with the expressionof cytotoxic proteins and cytokines in non-nasal peripheral T-cell lymphomas.
http://sunzi.lib.hku.hk/hkuto/searchSubject.jsp?subj=Epstein Barr virus
Epstein-Barr Virus
epsteinbarr virus (Group 1). epstein-barr virus (EBV) is a gamma-1 herpesvirus foundthroughout all human populations, with a prevalence of over 90% in adults.
http://193.51.164.11/htdocs/monographs/vol70/70-ebv.htm

Extractions: (Group 1) For definition of Groups, see Preamble Evaluation VOL. : 70 (1997) (p. 47) Epstein-Barr virus (EBV) is a gamma-1 herpesvirus found throughout all human populations, with a prevalence of over 90% in adults. Primary infection usually occurs in early childhood and is asymptomatic, whereas delayed primary infection may cause a self-limiting lymphoproliferative disease, infectious mononucleosis. Infection results in the establishment of a life-long carrier state characterized by the persistence of antibodies to several viral gene products and the secretion of infectious virus in saliva. Saliva is the usual vehicle of transmission. EBV can induce growth transformation of human and primate B-lymphocytes in vitro Cellular and perhaps humoral immune responses contribute to the control of primary EBV infection and mediate the transition to asymptomatic persistence of the virus in healthy carriers. The humoral responses include the production of neutralizing antibodies directed to the CD21-binding protein gp350/320 and antibodies directed against lytic and latent gene products. Cells expressing type-III latency, which are detected during primary infection, are promptly eliminated by CD8 major histocompatibility (MHC) class I-restricted cytotoxic T lymphocytes which recognize epitopes from all the latent viral proteins except EBNA-1. Accordingly, only EBNA-1 appears to be expressed in the latently infected B cells that persist in healthy virus carriers. The failure of this protein to elicit cytotoxic T-lymphocyte responses could be instrumental in allowing persistence of virus-infected cells in immunocompetent hosts. CD4
Txt001lyb: Epstein-Barr Virus Infection: Basis Of Malignancy And Potential For T
EpsteinBarr virus infection basis of malignancy and potential for therapy. EpsteinBarrvirus (EBV) is a member of the Lymphocryptovirus genus.
http://www-ermm.cbcu.cam.ac.uk/01003842h.htm

Extractions: Author contact details Lymphocryptovirus genus. These viruses are closely related members of the gamma herpesvirus family and are similar to each other with respect to genomic structure and gene organisation. The EBV genome is composed of linear, double-stranded DNA, which is approximately 172 kb in length (see Fig. 1a; ), and regions of the EBV genome have become known by their position on a Bam HI restriction endonuclease map of the genome (see Fig. 1b EBV is orally transmitted and infectious virus can be detected in oropharyngeal secretions from infectious mononucleosis (IM) patients, from immunosuppressed patients and, at lower levels, from healthy EBV-seropositive individuals (Ref. ). EBV enters B cells by interaction of the major viral glycoprotein gp350/220 with the complement receptor (CR2/CD21, which is the receptor for complement component C3d). The penetration of B cells by EBV also involves the viral glycoproteins gp25 (gL) and gp42/38 in a complex with viral gp85 (gH). This complex mediates an interaction between EBV and major histocompatibility complex (MHC) class II molecules, which serve as a co-receptor for virus entry into B cells (Ref. Crosslinking of CD21 activates B cells from their resting state. Some of the immediate effects that occur simply from this binding event include Lck activation and calcium (Ca
ResGen : Products : Epstein-Barr Virus Early EBER RNA Probe
Yeast DNA Synthesis Mapping Reagents Primers, Markers, Probes Gene Discovery ServicesRequest a Catalog epsteinbarr virus early EBER RNA Probe This page is
http://www.resgen.com/products/EBVEBER.php3

Extractions: Product Info Ordering Related Products Technical Data Contact Info This biotin labeled probe detects the most abundant early RNA sequence in Epstein-Barr virus infections. It provides an excellent screening procedure with high sensitivity for the presence of EBV infections in mononucleosis, lymphoproliferative disorders, and immunodeficiency states. This probe works in both formalin and HISTO CHOICE fixed tissues and cell lines. The prediluted form is provided in a convenient dropper bottle and is stored at 4°C, the lyophilized probe is stored at -20°C. Sufficient for 100 slides. Ref: Montone, K.T. and Brigati, D.J. (1994) J. of Histotechnology 17, No. 3, 195-201. For our recommended protocols, please see our ftp site Epstein-Barr Virus early EBER RNA Probe - 10 µg lyophilized : This biotin labeled probe detects the most abundant%0D%0Aearly RNA sequence in Epstein-Barr virus infections. It provides%0D%0Aan excellent screening procedure with high sensitivity for the%0D%0Apresence of EBV infections in mononucleosis, lymphoproliferative%0D%0Adisorders, and immunodeficiency states. This probe works in both%0D%0Aformalin and HISTO CHOICE %26reg; fixed tissues and cell lines.%0D%0AThe prediluted form is provided in a convenient dropper bottle%0D%0Aand is stored at 4%26%23176;C, the lyophilized probe is stored at%0D%0A-20%26%23176;C. Sufficient for 100 slides.
ResGen : Products : Epstein-Barr Virus DNA NotI/PstI Repeat Region Probe
Synthesis Mapping Reagents Primers, Markers, Probes Gene Discovery Services Requesta Catalog epsteinbarr virus DNA NotI/PstI Repeat Region Probe This page
http://www.resgen.com/products/EBVProbe.php3

Extractions: Product Info Ordering Related Products Technical Data Contact Info This biotin labeled probe produces nuclear staining in Epstein-Barr virus infected lymphocytes which are in the late or productive stage of the infection. The prediluted form is provided in a convenient dropper bottle and is stored at 4°C, the lyophilized probe is stored at -20°C. This probe works in both formalin and HISTO CHOICE fixed tissue sections. Sufficient for 100 slides. Ref: Montone, K, Budgeon, L.R.,%0D%0Aand Brigati, D.J. Detection of Epstein- Barr virus genomes by in situ DNA hybridization with a terminally biotin-labeled synthetic oligonucleotide probe for EBV NotI and PstI tandem repeatregions. (1990) Modern Pathology 3 For our recommended protocols, please see our ftp site
Epstein-Barr Virus.
epsteinbarr virus. Pathology. epstein-barr virus (EBV) is a curious virus, affectinga surprisingly large number of the population (somewhere around 20%).
http://www.diseasedir.org.uk/infect/vir02.htm

Extractions: Epstein-Barr Virus. Disease type: Viral infection. Figure V.02.01 - The EBV attaches to the outside of the cell, and is internalised by the cell. Once inside the virus releases its DNA content, which enters the nucleus and integrates into the hosts DNA. The viral proteins will then be expressed, to begin the formation of new virus. Pathology With EBV this process is not 100% effective, and a small population of EBV +ve cells will remain. This gives rise to life-long infection. Once EBV has been caught, it cannot be removed. Figure V.02.03 - Translocation of EBV through the genome. This erroneous copying can lead to cancer. Aetiology EBV by itself does not cause disease. But its constant gene translocations can. B cells, of the immune system, will secrete Antibody at a constant level throughout the cells life-span. B cells can become cancerous if a oncogene is placed next to the Antibody gene. Antibodies are produced in great excess, and as the oncogene is next door to the antibody, it too will be produced in excess. The Oncogene will result in a leukemia. EBV has been linked positively with the incidence of Hodgkins disease, Burkitts Lymphoma, and Nasophangeal carcinoma, to name but a few. Figure V.02.02 -
MTC - Ingemar Ernberg's Group - Epstein-Barr Virus
Biobanking Biocomplexity/bioinformatics Cancer genetics epsteinbarr virus HIV andEBV Nasopharyngeal Carcinoma Oxidative radicals Signal Transduction Virus
http://www.mtc.ki.se/groups/ernberg/epstein.htm

Extractions: All tumor-associated viruses have evolved strategies for survival and spread as part of their physiologic infection, which affects cell cycle and apoptosis control. By inducing transient proliferation in their target organ/cells they prepare for lytic replication by engaging more cells, as an amplification mechanism. Virus infections per se induce apoptosis, which may be regarded as a defence mechanism by the host/host cell. Progression from cells at risk to overt tumor only takes place if late replicative events are truncated or blocked (e.g. by integration, accidental infection of wrong cell type), if the infection cannot be handled by the immune system and/or if the infection raises an inappropriate host reaction. Epstein-Barr virus (EBV) infection in man, illustrates these points, due to extenisve though incomplete knowledge on several of these issues. EBV is the most common virus in the human population (>90% of adults carry the virus), it normally gives rise to an inconspicuous or benign infection, paradoxically, however, under rare circumstances it induces tumors and in vitro it is very efficient in transforming its natural host cell, the B-lymphocyte.
Epstein-Barr Virus Network
epsteinbarr virus Network. updated March 19, 1997 by Won Keun Lee The InternationalEBV Association exists to promote research on epstein-barr virus..
http://bioserver.myongji.ac.kr/ebv.html

Extractions: updated March 19, 1997 by Won Keun Lee EBV Home International Association for Research on EBV and Associated Diseases. The International EBV Association exists to promote research on Epstein-Barr virus.. EBV Report EBV Report has become the official journal of the International EBV Association. Association news and notices of matters to be discussed at... Epstein-Barr Virus Unit The Queensland Institute of Medical Research Epstein-Barr Virus Unit. Research Summary. Experimental Immunology. Simone Cross Ihor Misko Chris Schmidt. EBV Biology. Jacqueline Burrows Beverley Kerr... - Epstein Barr Virus Infection is widespread. Most people have antibodies by the time they reach adulthood. Following primary infection, the virus persists.
Epstein-Barr Virus
epsteinbarr virus. epstein-barr virus (EBV), the cause of classicinfectious mononucleosis, is an ubiquitous herpes group virus.
http://www.labcorp.com/hcp/medical_specialties/infectious_disease/ebv/body_ebv.h

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