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Erythromelalgia:     more detail

Small fiber neuropathy underlies erythromelalgia.(Skin Disorders): An article from: Family Practice News by Jane Salodof MacNeil, 2006-04-01 Red scrotal syndrome: a localized phenotypical expression of erythromelalgia.(CASE REPORTS)(Case study): An article from: Journal of Drugs in Dermatology by Noel Prevost, Joseph C., III English, 2007-09-01 A case of erythromelalgia: good response to treatment with gabapentin.(CASE REPORTS)(Clinical report): An article from: Journal of Drugs in Dermatology by Ali Murat Ceyhan, Ipek Gurses, et all 2010-05-01 Two cases of erythromelalgia (Mitchell) by Daniel Webster Prentiss, 1897 A case of erythromelalgia,: With microscopical examination of the tissue from an amputated toe, (American journal of the medical sciences) by S. Weir Mitchell, 1899 The occurrence of erythromelalgia in diseases of the spinal cord: An account of ten cases by James Collier, 1898 Erythromelalgia: Report of two cases, with cure. From the clinic of Dr. Otto Lerch, professor of medical diagnosis, postgraduate department, Tulane University by Albert Emile Fossier, 1913 Hysterical rapid respiration, with cases: Peculiar form of rupial skin disease in an hysterial woman by S. Weir Mitchell, 1893

lists with details

1. The Erythromelalgia Association
   A non-profit organization dedicated to research and education regarding this painful disorder. Offers Category Health Conditions and Diseases erythromelalgiaWelcome To The erythromelalgia Association. What's New? March 2003 Newsletter FootSteps; Many new articles in the online library; New member passwords  
   http://www.erythromelalgia.org/
   
   Extractions: Erythromelalgia (EM) is a rare condition that can cause redness and pain in all parts of the body, but most frequently the feet and hands (extremities). It is characterized by intense, burning pain, severe redness (erythema), and increased skin temperature that may be episodic or almost continuous in nature. Although Erythromelalgia typically affects both sides of the body (bilateral), it may sometimes involve only one side (unilateral). In addition, the disease course may be extremely variable from case to case. For example, in some individuals, symptom onset may be gradual, with the condition potentially remaining relatively mild for years. However, in others, it may have a sudden onset, possibly spreading and becoming severe over weeks. The specific underlying cause of erythromelalgia remains unknown. However, the condition is thought to result from vasomotor abnormalities or dysfunction in the normal constriction and dilation of the diameter of certain blood vessels, leading to abnormalities of blood flow to the extremities. Erythromelalgia may be an isolated, primary condition or occur secondary to various underlying disorders.

2. THE MERCK MANUAL, Sec. 16, Ch. 212, Peripheral Vascular Disorders
   The cause of primary erythromelalgia is unknown. Secondary erythromelalgia may occur in patients who have  
   http://www.merck.com/pubs/mmanual/section16/chapter212/212f.htm
   
   Extractions: This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 16. Cardiovascular Disorders Chapter 212. Peripheral Vascular Disorders Topics [General] Peripheral Arterial Occlusion Thromboangiitis Obliterans Raynaud's Disease and Phenomenon ... Lipedema Erythromelalgia A rare syndrome of paroxysmal vasodilation with burning pain, increased skin temperature, and redness of the feet and, less often, the hands. The cause of primary erythromelalgia is unknown. Secondary erythromelalgia may occur in patients who have myeloproliferative disorders, hypertension, venous insufficiency, diabetes mellitus, SLE, RA, lichen sclerosus et atrophicus, gout, spinal cord disease, or multiple sclerosis. Diagnosis of erythromelalgia is based on the relationship of complaints to increased skin temperature. Secondary types should be differentiated from the rare primary type because correction of an underlying disorder may relieve symptoms. Differential diagnosis includes posttraumatic reflex dystrophies, shoulder-hand syndrome, causalgia, Fabry's disease, and bacterial cellulitis. Because erythromelalgia may precede a myeloproliferative disorder (even by several years), frequent blood counts may be indicated to allow early diagnosis and treatment of the latter. Attacks can be avoided or aborted by rest, elevation of the extremity, and cold applications. Therapy is not always successful. In primary erythromelalgia, aspirin 650 mg 1 to 4 times/day may provide prompt, prolonged relief. Avoiding factors that produce vasodilation is usually helpful, and vasoconstrictors (eg, ephedrine 25 mg po, propranolol 10 to 40 mg po qid, methysergide 1 mg po q 4 h) may also provide relief. In secondary erythromelalgia, the underlying disease should be treated.

3. EMedicine - Erythromelalgia : Article By Robert J Nardino, MD
   Background erythromelalgia is a rare disorder characterized by burning pain and warmth and redness of the extremities.  
   http://www.emedicine.com/med/topic730.htm
   
   Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Last Updated: August 6, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: erythermalgia AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Robert J Nardino, MD , Director, Internal Medicine Residency Program, Assistant Clinical Professor, Department of Internal Medicine, Hospital of Saint Raphael, Yale University School of Medicine Coauthor(s): Andrea LM Silber, MD , Fellowship Director of Oncology, Hospital of St Raphael; Clinical Assistant Professor, Department of Medicine, Section of Hematology-Oncology, Yale University School of Medicine Robert J Nardino, MD, is a member of the following medical societies: American College of Physicians-American Society of Internal Medicine , and Society of General Internal Medicine Editor(s): Rodger L Bick, MD, PhD

4. Erythromelalgia
   erythromelalgia If you have RED, BURNING, FEET or HANDS, check this page out!!!  
   http://www.homestead.com/lareisaplaza/erythromelalgia.html

5. MESSAGES.TERADEX.COM - Health/Fitness/Diseases/Rare Disorders/Erythromelalgia
   MESSAGES / Health/Fitness / Diseases / Rare Disorders / erythromelalgia. Page 1 of 1  
   http://messages.teradex.com/Health_Fitness/Diseases/Rare_Disorders/Erythromelalg

6. Erythromelalgia Diagnosis
   erythromelalgia Diagnosis. Medical Explanation and EM Life Style. Thefollowing medical rare. Raynaud's Syndrome and erythromelalgia. As the  
   http://www.erythromelalgia.org/Diagnosis.asp
   
   Extractions: “EM results from a maldistribution of blood flow with some areas not getting enough blood and calling for more. The extra blood gets through other open vessels, including arteriovenous anastomosis, that is, the connection between the arterial and venous systems. This vicious cycle continues to worsen until the overall appearance of the skin is of too much blood flow. Vasodilating drugs sometimes work to open the shut vessels. When that happens, the vessels stop calling for more blood and the overall system may normalize or at least improve its function.” Dr. Cohen further says: “even mild erythromelalgia can greatly affect normal functioning and quality of life. Patients avoid warm weather and limit their activities to cool or air conditioned locations. Some move to cooler climates...many patients cannot wear socks or closed shoes even in winter.” When patients are severely affected, they can be house bound because of the continually painful symptoms. Elevation of the affected limbs becomes necessary and normal life is disrupted.

7. NORD Erythromelalgia
   Offers the synonyms, a general discussion and further resources.  
   http://www.rarediseases.org/cgi-bin/nord/abstrfly?id=syce5dv4&mv_arg=RDB-245

8. Erythromelalgia
   Subscribe now . erythromelalgia. The doctor did some nerve conduction tests andsaid it was more likely a problem with blood vessels called erythromelalgia.  
   http://healthlink.mcw.edu/article/990317252.html
   
   Extractions: Subscribe now >> Q: I enjoy reading your column and your article discussing Raynaud's disease was of particular interest to me. However, my feet get extremely hot and red. Both plantar fasciitis and peripheral neuropathy were suggested as possibilities. After much frustration, I went to Marshfield Clinic. The doctor did some nerve conduction tests and said it was more likely a problem with blood vessels called erythromelalgia. I am still at a loss as to why I have it and what I can do to treat it. Is that the end of my story or can you tell me more about it and where I might find someone familiar with this very uncomfortable situation? A: You have a rare problem, that is almost the opposite of Raynaud's , in which the fingers and toes turn color and get painful with exposure to cold. With erythromelalgia, the hands and feet get very red and painful in a warm environment. It is more common in men and usually begins around middle age. The feet are usually more involved than the hands, especially when the feet are hanging down for long periods. Erythromelalgia may be associated with high blood pressure, too many platelets or red cells in the blood, or a side effect of medications like nifedipine (blood pressure medicine).

9. E-Doc: Erythromelalgia
   Medical Dictionary. erythromelalgia  
   http://www.edoc.co.za/medilink/dict/1545.html

10. Katalog - Wirtualna Polska
    Serwis Katalog w Wirtualna Polska S.A. pierwszy portal w Polsce.  
    http://katalog.wp.pl/DMOZ/Health/Conditions_and_Diseases/Rare_Disorders/Erythrom

11. EMedicine - Erythromelalgia : Article Excerpt By: Robert J Nardino, MD
    erythromelalgia erythromelalgia is a rare disorder characterized by burning painand warmth and redness of the extremities. Excerpt from erythromelalgia.  
    http://www.emedicine.com/med/byname/erythromelalgia.htm
    
    Extractions: (advertisement) Synonyms, Key Words, and Related Terms: erythermalgia Background: Erythromelalgia is a rare disorder characterized by burning pain and warmth and redness of the extremities. Confusion exists in the literature concerning nomenclature and classification, but, in general, a distinction is made between primary (idiopathic) and secondary erythromelalgia (most commonly associated with myeloproliferative disorders), as well as early- and late-onset disease. erythros (red), melos (extremities), and algos (pain). In 1938, Smith and Allen proposed the term erythermalgia to emphasize the characteristic warmth. They also proposed a distinction between primary (idiopathic) and secondary (due to underlying neurologic, hematologic, or vascular problems). Pathophysiology: Arteriolar fibrosis and occlusion with platelet thrombi occur, but not in all cases. Platelets have been demonstrated to have abnormal hyperaggregability. Platelet kinetic studies show decreased platelet survival, predominantly due to consumption. Prostaglandins and cyclooxygenase apparently play an important pathogenetic role. Pathophysiology in cases not associated with thrombocythemia is less clear but does not involve platelet-mediated inflammation and thrombosis. This is the major reason that Drenth and Michiels distinguish between erythromelalgia and erythermalgia. One postulate is maldistribution of skin perfusion resulting from arteriovenous shunting, leading to an imbalance between thermoregulatory and nutritive perfusion. Another is decreased sympathetic vasoconstrictor response to certain stimuli.

12. Homemade Poetry
    com/ Health/ Conditions_ and_ Diseases/ Rare_ Disorders /erythromelalgia.htm. Notice Microsoft has no responsibility  
    http://groups.msn.com/HomemadePoetry/erythromelalgia.msnw
    
    Extractions: Homemade Poetry HomemadePoetry@groups.msn.com Groups Home My Groups Language Help ... Tools ~~~ERYTHROMELALGIA~~~ dedication to two family members written by Marie~ May 19th 2002 http://www.erythromelalgia.org/ http://www.homestead.com/lareisaplaza/eryfaqs.html http://www.emedicine.com/med/topic730.htm http://www.slider.com/Health/Conditions_and_Diseases/Rare_Disorders ... /Erythromelalgia.htm Notice: Microsoft has no responsibility for the content featured in this Group. Click here for more info. MSN - More Useful Everyday MSN Home My MSN ... GetNetWise

13. Erythromelalgia
    erythromelalgia Menu. This is a webforum to discuss and comment on erythromelalgia. Nueropathy erythromelalgia (4/16/99) 1225 AM; (4/8/99) 113 AM; HELP!  
    http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaMenu.html
    
    Extractions: This is a webforum to discuss and comment on Erythromelalgia. Click here to Enter a new Neurology WebForum article... This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. Therefore, the opinions and statements made in all articles and replies do not represent the official opinions of MGH and MGH Neurology. Neither is MGH or MGH Neurology responsible for the content of any articles or replies. No messages are screened for content. - Very Important Message! - Please Click Here to Read Current Posts: Nov 13, 1997 to Present Useful Websites can be found and posted here! IMPORTANT: If this page seems to be missing recently added documents, click the "Reload Page" button on your Web Browser to update the menu. Return to the main Neurology WebForum Page. These forums are maintained by the Department of Neurology at Massachusetts General Hospital

14. Erythromelalgia Types And Treatments
    erythromelalgia Types and Treatments. This article submitted by Karl Granat on10/13/98. Email Address katlgra@aol.com Form letter on erythromelalgia  
    http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaF/10.13.981.41PMErythromel
    
    Extractions: What is Erythromelalgia? Erythromelalgia is a painful condition that has a very distinctive pattern of symptoms. It is diagnosed when the extremities are red, warm and painful- the pain is often described as burning. This pain is only relieved by cooling (often in cold water) or the elevation of the affected extremities. Secondary Erythromelalgia: This condition often accompanies tissue destroying disorders such as arthritis, lupus, or diabetes. It also often associated with potentially fatal disorders of the blood as well- which is why all who suffer from these symptoms should seek a diagnosis and treatment from a physician and have periodic blood tests thereafter. Secondary erythromelalgia can very often be treated successfully by your physician.

15. DIRECTORY.TERADEX.COM - Health/Fitness/Diseases/Rare Disorders/Erythromelalgia
    Groups A support group for those willing to help others who have erythromelalgia. Includes joining instructions.  
    http://directory.teradex.com/Health_Fitness/Diseases/Rare_Disorders/Erythromelal
    
    Extractions: Search through: Entire site Erythromelalgia DIRECTORY Health/Fitness Diseases Rare Disorders ... EM at Yahoo! Groups - A support group for those willing to help others who have Erythromelalgia. Includes joining instructions. Erythromelalgia in The Merck Manual - A basic description of this disorder, which causes severe burning, pain, and redness, primarily in the hands and feet. NORD: Erythromelalgia - Offers the synonyms, a general discussion and further resources. The Erythromelalgia Association - A non-profit organization dedicated to research and education regarding this painful disorder. Offers details about the disorder, the organization, FAQs and membership information.

16. Erythromelalgia
    Subject erythromelalgia Topic Area Heart Disease Forum The Heart Forum QuestionPosted By Del on Monday, January 11, 1999 I don't even know for sure if  
    http://www.medhelp.org/forums/cardio/archive/7658.html
    
    Extractions: I don't even know for sure if this is the correct forum, my searches at many sites come up empty, but since Erythromelalgia is connected to problems with the vascular system, I decided to try here. I'm trying to find GOOD, basic information/explanations for Erythromelalgia. I have been diagnosed but without any clear understanding as to what this will mean - prognosis. It is secondary to peripheral neuropathy, but doesn't seem to be a neurological disorder, although many of the symptoms overlap. I'm confused! I'll appreciate any help you can give me. Thanks!

17. Erythromelalgia Articles, Support Groups, And Resources
    erythromelalgia articles, support groups, and resources for patientsfrom Med Help International (www.medhelp.org). erythromelalgia.  
    http://www.medhelp.org/HealthTopics/Erythromelalgia.html

18. Arch Dermatol -- Page Not Found
    Arch Dermatol. 136;406409, March 2000, erythromelalgiaA Mysterious Condition?,Cato Mork, MD; Knut Kvernebo, PhD. erythromelalgia A Mysterious Condition?  
    http://archderm.ama-assn.org/issues/v136n3/ffull/ded9027.html
    
    Extractions: The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

19. Arch Dermatol -- Page Not Found
    Natural History of erythromelalgia Presentation and Outcome in 168 Patients AuthorInformation Mark DP Davis, MB, MRCPI; W. Michael O'Fallon, PhD; Roy S  
    http://archderm.ama-assn.org/issues/v136n3/abs/dst9040.html
    
    Extractions: The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

20. New Page 4
    The symptoms you describe are classic for something called *erythromelalgia*,which literally means red, painful extremities. erythromelalgia  
    http://www.the-doctors-inn.com/newpage4.htm

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