University Of Stellenbosch, Community Dentistry Oral hairy leukoplakia. hairy leukoplakia (HL) is rarely manifested in childrenwith perinatally acquired HIV infection. ^ Herpes simplex virus infections. http://www.oralhivlesions.com/children.htm
Extractions: Molluscum contagiosum Several studies have emphasised the prognostic significance of oral candidiasis and hairy leukoplakia as predictors of immunosuppression and AIDS-defining conditions in adults. Similar studies documenting the prognostic implications of oral lesions in HIV-seropositive children have emerged recently. Cervical lymphadenopathy and oral candidiasis are the most prevalent head and neck manifestations. Both of these lesions are associated with a decline in the number of CD4 T cells and increase in IgG. Oral candidiasis is related significantly to the CDC staging of HIV disease, with the lesion being more prevalent in children with symptomatic HIV infection. There is also a significant relationship between oral candidiasis, declining CD4 T cell and neutrophil (PMN) counts in HIV-infected children. Children infected with HIV do not necessarily develop AIDS by a set pattern, but can be divided into long- and short-term survivors. A decreased CD4 T cell count early in life can be predictive of survival outcome. Lymphadenopathy and parotitis are more frequent clinical findings in long-term survivors (LTS) than in short-term survivors (STS) and these signs are positive predictors of survival in children. On the other hand, children having an onset of opportunistic infections early in their disease course generally have a poor prognosis.
University Of Stellenbosch, Community Dentistry Oral hairy leukoplakia. Oral hairy leukoplakia is useful for the clinical stagingof HIV. ^ Herpes simplex. Lesions on the gums, hard palate and lips. http://www.oralhivlesions.com/chart_2.htm
Jennifer Webster-Cyriaque, DDS, PhD These viruses cause AIDS defining lesions such as Kaposi's Sarcoma, hairy leukoplakia(HLP) and Herpes Simplex Virus (HSV)associated ulcerative disease. http://www.med.unc.edu/wrkunits/2depts/microimm/faculty/virology/webster.html
Extractions: A goal of our laboratory is to understand viral molecular pathogenesis in oral disease, in states of health and immunocompromise. There are eight known human herpes viruses that cause persistent infections and are shed into the oral cavity during immunosuppression causing increased morbidity. These DNA viruses are all marked by their ability to establish permanent, persistent infections where the viral infection may be latent, chronic, or transforming. These viruses manipulate host immune recognition and response to allow for these continuous infections and affect specific cellular pathways to induce cell growth or death. Our laboratory seeks to understand the critical molecular interactions that occur between the virus and the host that govern the development of oral lesions and malignancies. DNA viruses often infect and replicate in oral epithelia and are increasingly associated with oral neoplasms. We are performing studies that examine the pattern of viral gene expression and cellular effectors of viral gene products to determine which viral products and cellular genes are important to the development of oral neoplasms. These types of studies aid understanding of molecular mechanisms of oral disease. Selected Publications *Walling DM, Perkins AG, Webster-Cyriaque J, Resnick, and Raab-Traub N. The Epstein-Barr Virus EBNA2 Gene in Oral Hairy Leukoplakia: Strain Variation, Genetic Recombination, and Transcriptional Expression. Journal of Virology. Dec 1994, p. 7918-26.
The WIHS Woman--Spring 2001, Page 3 Thrush or oral candidiasis and hairy leukoplakia were the most common oral lesionsfound in the WIHS. hairy leukoplakia may be an indicator of HIV infection. 3. http://itsa.ucsf.edu/~wihs/sf/newsletter/spring01/page3.html
Extractions: ral lesions are widely regarded by health-care providers as a means to study the progression of HIV infection. Lesions such as oral candidiasis ("thrush") and hairy leukoplakia have been connected with the presence of HIV infection along with other markers such as CD4 cell count. In fact oral lesions are among the earliest indicators of the effects of HIV on a patient's immune system. Why? One reason is that the flora (bacteria and fungi) that lives in your mouth may become harmful due to a change in your immune system.
Oral AIDS Center, UCSF Several were responsible for the discovery of hairy leukoplakia (HL), its associationwith EpsteinBarr virus (EBV), and its relationship to HIV infection and http://itsa.ucsf.edu/~ucstoma/Oac.htm
Extractions: Oral AIDS Center John S. Greenspan, Director Deborah Greenspan, Clinical Director Yvonne DeSouza, Associate Director The Oral AIDS Center (OAC) is one of the world's leading centers for the study of the oral manifestations of HIV infection. The OAC was established in 1986 by a group of investigators and clinicians who had been working together since the early days of the AIDS epidemic. The investigators of the OAC, most of whom are faculty and staff members in the Department of Stomatology, have published more than 400 papers, made more than 450 presentations at research meetings, and given innumerable talks to medical, dental and other health-sciences practitioner groups. Today, the OAC has developed numerous collaborations within major AIDS epidemiology and clinical research groups in California, the United States, Europe, Africa, South America, and Asia. The OAC comprises many of the leading clinicians and investigators in the field of oral and dental aspects of AIDS. Several were responsible for the discovery of hairy leukoplakia (HL), its association with Epstein-Barr virus (EBV), and its relationship to HIV infection and AIDS. Our group was also among the first to describe the periodontal infections associated with HIV, and we were the first group to initiate a systematic study of the oral features of simian AIDS. The NIDCR program project grant that supports much of the research of the OAC has been refunded through April 2000, allowing for the continuation of research on the pathogenesis of oral lesions associated with HIV infection. This continuation grant raises the total NIH support for the OAC to more than $11 million. The OAC has recently submitted a competing application for years May 2000-April 2005. In February 1999, members of the OAC met with its external Board of Scientific Advisors for a focused review of the OAC's future plans. Members of the Board include Drs. Charles Bertolami, Murray Gardner (UC Davis), John Greene (UCSF School of Dentistry), Mitchell Katz (San Francisco Department of Public Health), Richard Locksley (UCSF School of Medicine), Daniel Malamud (University of Pennsylvania), Nancy Raab-Traub (University of North Carolina), Paul Volberding (San Francisco General Hospital), Warren Winkelstein (UC Berkeley), and Harald zur Hausen (German Cancer Center, Heidelberg).
Walling goals are to investigate mechanisms of pathogenesis in EpsteinBarr virus (EBV)-associateddiseases, including oral hairy leukoplakia, nasopharyngeal carcinoma http://www.utmb.edu/infectious_diseases/WALLING.HTM
HealthFirst A condition often confused with oral thrush, because it looks much thesame, is oral hairy leukoplakia. However, oral hairy leukoplakia http://www.healthfirst.co.za/hiv.articles.asp?HivID=79
PAST QUESTIONS - Mouth Matters Q 1 hairy leukoplakia. My doctor has told me that I have hairy leukoplakia.I have tried a pridex rinse but it did not help. If http://www.geocities.com/~jenniferjensen/QUESTIONS/mouth.htm
Extractions: Q Hairy Leukoplakia My doctor has told me that I have hairy leukoplakia. I have tried a pridex rinse but it did not help. If you have any other suggestions please let me know. A: Barbara Scott, MPH, RD responds: Administrator's note: For some additional tips check out Jennifer's article The Mouth:Its Care and Feeding Q Perleche What is perleche? Is it related to yeast or thrush? A: Charlie Smigelski, RD responds: Administrator's Note: According to Taber's Cyclopedic Medical Dictionary , perleche is a "disorder marked by fissures and epithelial desquamation at corners of the mouth, esp. seen in children. May be due to oral candidiasis or may be a symptom of dietary deficiency, esp. riboflavin deficiency.") As noted in the above definition, perleche is often associated with the growth of Candida/yeast cells in the corner of the mouth. Since Candida has been modestly correlated with low selenium levels, I would encourage you to check your supplement intake and be sure you are getting 200 mcg of selenium a day. I recall a conversation with Jennifer when she advocated 400 mcg or more a day. I do suggest the higher amounts for Hep C poz people. Hep C is an RNA virus whose growth is sensive to selenium/glutathioone deficiencies. B vitamin deficencies (like riboflavin) also produce cracks in the corner of the mouth. This is different in its cause from the yeast-generated condition, but obviously a good B Complex vitamin is in order. I often recommend a Complex 25 or a Complex 50 to get enough.
Extractions: The Prevalence of HIV-Related Oral Lesions in a Primary Oral Health Care Practice; Implication for Service and Teaching Georgina P. Zabos, Eli Rachlin, Yong Bae Whang, Woosung Yun (Division of Community Health, School of Dental and Oral Surgery, Columbia University) The Columbia University School of Dental and Oral Surgery's HIV-related primary oral health care (POHC) program served over 300 adult patients over the past three and a half years. The objective of this report is to evaluate the prevalence of HIV-related oral lesions in this population. In this urban, under-served, mostly minority patient population approximately 40% of the patients had HIV-related oral lesions during the 2.5 years of the study. Since most of the care provided during this time was routine primary oral health care, and the most common oral lesions were oral candidiasis and oral hairy leukoplakia, we conclude that general practitioners can meet most of the HIV/AIDS patients' need for primary oral health care. The team approach is essential in order to coordinate medical and dental aspects of care. Implications for teaching include the necessity to provide not only didactic instruction but hands-on experience to all postgraduate general dentistry trainees in HIV/AIDS POHC
Oral Hairy Leukoplakia Oral hairy leukoplakia. This article submitted by on 1/18/99. EmailAddress Does anyone know what this looks like? the descriptions http://neuro-www.mgh.harvard.edu/forum/HIVandInfect.DiseaseF/1.18.998.17PMOralHa
Extractions: Does anyone know what this looks like? the descriptions that i have read say that these patches are thick and hard and can be corrugated or hairy. Can they be faint and come and go? I have had spots along the edge of my tongue, but they are not hard and they do no stay. Otherwise they fit the description, even the ridge on the inside of my cheek. my doc says this is nothing. Next Article
Oral Hairy Leukoplakia Neither is MGH or MGH Neurology responsible for the content of any articlesor replies. No messages are screened for content. Oral hairy leukoplakia. http://neuro-www.mgh.harvard.edu/forum_2/HIVandInfect.DiseaseF/7.11.997.50PMOral
Extractions: This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. Therefore, the opinions and statements made in all articles and replies do not represent the official opinions of MGH and MGH Neurology. Neither is MGH or MGH Neurology responsible for the content of any articles or replies. No messages are screened for content. This article submitted by on 7/11/99.
Extractions: October 25, 1996 Re: PROCAARE: RE: REQUEST FOR INFORMATIONKENYA (fwd) Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH (fwd) October 23, 1996 PROCAARE: BASIC SCIENCESUBTYPES (02) October 22, 1996 PROCAARE: RE: REQUEST FOR INFORMATIONKENYA October 21, 1996 PROCAARE: BASIC SCIENCESUBTYPES Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH AFRICA (fwd) Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH AFRICA (fwd) PROCAARE: REQUEST FOR INFORMATIONKENYA RE: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH AFRICA (fwd) Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH (fwd) Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH AFR (fwd) Re: PROCAARE: REQUEST FOR INFORMATIONHIV INFECTIONSOUTH AFRICA (fwd) October 17, 1996
Searchalot Directory For Hairy Leukoplakia Related Web Sites. Forum on HIV and Oral Health Information resources on hairyleukoplakia (HK) and other oral conditions, including FAQs, from The Body. http://www.searchalot.com/Top/Health/ConditionsandDiseases/InfectiousDiseases/Vi
Extractions: Home Search News Email Greetings Weather ... Global All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo! Yahoo! Auctions Yahoo! News Yahooligans Zeal Sponsored Links Top Health Conditions and Diseases Infectious Diseases ... Epstein-Barr Virus : Hairy Leukoplakia Related Web Sites Forum on HIV and Oral Health - Information resources on hairy leukoplakia (HK) and other oral conditions, including FAQs, from The Body. All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo!
UNC Lineberger: Faculty Research Profiles These viruses cause AIDS defining lesions such as Kaposi's Sarcoma,hairy leukoplakia (HLP) and HSVassociated ulcerative disease. http://cancer.med.unc.edu/researchers/DisplayByList.asp?ID=226
Normal Oral Epithelium Supports Persistent EBV Infection In HIV- However, while productive EBV replication is needed for oral hairy leukoplakia tooccur, it is not sufficient by itself, according to a report in the December http://www.hivandhepatitis.com/recent/ois/010402d.html
White Oral Lesions / Sores Top of Page. hairy leukoplakia hairy leukoplakia is one of the mostcommon and characteristic lesions of HIV infection. Rarely, it http://www.dentalreference.com/html/white_lesions.html
Extractions: s="na";c="na";j="na";f=""+escape(document.referrer) related: oral cancer smoking chewing tobacco red lesions ... mouth sores White lesions of the oral mucosa are a multifactorial group of disorders, the color of which is produced by the scattering of light through an altered epithelial (mucosal/ gum, tissue) surface. The diagnosis and differential diagnosis of oral lesions should be left up to your physician or dentist and should be made on the basis of your medical history, clinical features, and laboratory tests. Clinical features - Three clinical varieties are recognized: homogenous (common), speckled (less common), and verrucous (rare). Speckled and verrucous leukoplakia have a greater risk for malignant transformation than the homogenous type. The average percentage of malignant transformation for leukoplakia varies between 4% and 6%.
Page Title EpsteinBarr Virsus (EVB) hairy leukoplakia is associated with HIV and may also bea marker of immunosuppression in medically compromised HIV-negative patients http://www.critpath.org/daac/page16.html
Extractions: cytomegalovirus (CMV), and varicella-zoster virus (VZV). Oral warts, due to the human papilloma virus (HPV) are also common. Clinically, these lesions are not different from those described in other medically compromised patient populations. Response to treatment and recurrence is different in the HIV/AIDS patient depending on the severity of immunosupression. Primary HSV infection (primary herpetic gingivostomatitis) is uncommon in the HIV-positive patient, and when observed it does not appear different from the same condition in the non-HIV-infected patient. Diffuse swelling, pain, transient vesicles, erythema and ulcerations are most evident on the attached gingiva and palatal mucosa. However, lesions are often widespread and involve perioral or other oropharyngeal sites. Associated signs and symptoms include fever, malaise, cervical lymphadenopathy, sialorrhea, halitosis, and dysphagia. Recurrent HSV infection: The clinical presentation includes multiple small vesicles (2-3 mm) that ulcerate and coalesce to form larger ulcers of the oral mucosa (vermillion, gingiva, dorsal tongue, hard palate)and perioral region. Persistence of a herpetic lesion for more than one month should alert the clinician to the possibility of immune deficiency.
Extractions: White Surface Lesions of Oral Mucosa Surface lesions of oral mucosa are divided into three groups based on their clinical features: epithelial thickening white lesions, surface debris white lesions, and white lesions due to subepithelial changes in the connective tissue. Epithelial thickening white lesions appear white because the pink to red color of the blood vessels in the underlying connective tissue is masked by the increased thickness of the epithelium. These lesions are asymptomatic, rough to palpation, and cannot be rubbed off with a gauze. They appear flat white when dried. Three of the epithelial thickening white lesions occur on the tongue: hairy tongue, hairy leukoplakia, and geographic tongue. Hairy tongue http://www.uiowa.edu/~oprm/AtlasWIN/AtlasFrame.html is the result of the accumulation of keratin on the dorsal surface of the tongue. Numerous causes have been proposed, but lack of mechanical abrasion to the dorsal tongue due to poor oral hygiene and/or a soft diet are probably the most important causes. The lesion presents as elongated filiform papillae having a hair-like appearance. The papillae are typically stained brown, black or other colors depending on the patient's diet and habits. Hairy tongue is typically not painful. Hairy tongue is not a serious condition, but warrants treatment for cosmetic and hygienic reasons. Treatment involves using a toothbrush, tongue blade, or tongue scraper to brush or scrape the dorsal surface of the tongue. The prognosis is good.
Prevence hairy leukoplakia (vlasatá leukoplakie jazyka) je sliznicní zmenou nejistéhopuvodu, nejcasteji kladenou do souvislosti s virem Epsteina Barrové. http://www.aids-hiv.cz/zubari.htm
