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Hemolytic Uremic Syndrome
A description of hemolytic uremic syndrome, where the bacteria comes from, who develops it, the symptoms Category Health Conditions and Diseases hemolytic uremic syndromehemolytic uremic syndrome (HUS), commonly referred to as HamburgerDisease , is a disease that affects the kidneys and other organs.
http://www.kidney.ca/hus-e.htm

Extractions: Hemolytic Uremic Syndrome (HUS), commonly referred to as "Hamburger Disease", is a disease that affects the kidneys and other organs. It poses a substantial threat to Canadian children as one of the leading causes of both acute and chronic kidney failure. HUS is more commonly seen in the warmer months of the year, following a gastrointestinal illness caused primarily by a particular strain of bacteria known as E.coli 0157:H7. While other types of E.coli are commonly found in the gastrointestinal tract of healthy humans, this particular strain (0157:H7) is not usually present except in diarrheal illnesses. This bacteria (E.coli 0157:H7) is known to produce toxins, which are the main cause of the symptoms related to the gastrointestinal illness. The most common symptoms of E.coli 0157:H7 Gastroenteritis are the following: People of all age groups are at risk for E.coli 0157:H7 gastroenteritis; however, young children and the elderly are at greater risk for more severe symptoms. This infection is highly contagious. Thousands of Canadians are identified with this infection each year and many epidemics have been reported in Canada (the most recent being Walkerton), the United States, and Europe. E.coli 0157:H7 bacteria originates in the intestines of animals and is carried typically in their feces which can contaminate meat during and after slaughter. This bacteria has been associated with consumption of undercooked ground beef (hence, "Hamburger Disease"), unpasteurized milk and cheese, cold cuts, hot dogs, chicken, pork, lamb, and contaminated water sources. Recent studies conducted by the Canadian Pediatric Kidney Disease Research Centre (CPKDRC), have also reported a strong association of this infection with person-to-person spread through the fecal-oral route. In addition, poor hand washing and improper food handling are high-risk factors for the spread of this bacteria.
EMedicine - Hemolytic Uremic Syndrome : Article By William Shapiro, MD
Written by William Shapiro MD., an article about hemolytic uremic syndrome. An introduction, lab studies, Category Health Conditions and Diseases hemolytic uremic syndromehemolytic uremic syndrome hemolytic uremic syndrome (HUS) is characterizedby acute renal failure, microangiopathic hemolytic anemia, fever, and
http://www.emedicine.com/emerg/topic238.htm

Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Emergency Medicine Hematology And Oncology Last Updated: July 29, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: HUS AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: William Shapiro, MD , Consulting Staff, Department of Urgent Care and Emergency Medicine, Scripps Clinic and Research Foundation William Shapiro, MD, is a member of the following medical societies: American Academy of Emergency Medicine American College of Emergency Physicians , and American College of Physicians Editor(s): William Gossman, MD , Assistant Professor, Department of Emergency Medicine, Chicago Medical School; Project Medical Director, Department of Emergency Medicine, Mount Sinai Hospital; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, Pharmacy, eMedicine; Jeffrey L Arnold, MD, FACEP, FAAEM
Hemolytic Uremic Syndrome
hemolytic uremic syndrome (HUS) is characterized by destruction of red blood cells,damage to the lining of blood vessel walls, and, in severe cases, kidney
http://www.niddk.nih.gov/health/kidney/summary/hus/

Extractions: Hemolytic (HEE-mo-LIT-ik) uremic (yoo-REE-mik) syndrome is a rare condition affecting mostly children under the age of 10. Hemolytic uremic syndrome (HUS) is characterized by destruction of red blood cells, damage to the lining of blood vessel walls, and, in severe cases, kidney failure. Most cases of HUS occur after an infection in the digestive system caused by the Escherichia coli bacterium found on contaminated food like meat, dairy products, and juice. The first stages of HUS frequently present with gastrointestinal symptoms such as abdominal pain, vomiting, and bloody diarrhea. This stage lasts from 1 to 15 days. Recovery from this acute colitic phase is the rule. However, more severe problems in the bowel and colon may develop in some cases. (The most vulnerable and severely stricken of children with HUS can die during the first acute stage of the diseasebetween 5 percent and 10 percent.) For most children with HUS, the vomiting and diarrhea stop after 2 or 3 days. Even when the gastroenteritis has stopped, the child does not recover full health, remaining pale, tired, and irritable. The bacteria originally lodged in the digestive system make toxins that enter the bloodstream, and these toxins destroy red blood cells. Small, unexplained bruises or small clot-sized hemorrhages visible in the mucosal lining of the mouth may occur because the toxins also destroy the platelets, cells that normally contribute to the clotting system. The damaged red blood cells and other factors may clog the tiny blood vessels in the kidneys or cause lesions in the kidneys, making the kidneys work harder to remove wastes and extra fluid from the blood. The child may produce little urine as a result. The body's inability to rid itself of excess fluid and waste may in turn cause hypertension or swelling of the hands and feet or may cause generalized fluid accumulation (edema).
Hemolytic Uremic Syndrome
Fact sheet summarizing hemolytic uremic syndrome.
http://www3.bc.sympatico.ca/me/patientsguide/huspg.htm

Extractions: Hemolytic (HEE-mo-LIT-ik) uremic (yoo-REE-mik) syndrome is a rare condition affecting mostly children under the age of 10. Hemolytic uremic syndrome (HUS) is characterized by destruction of red blood cells, damage to the lining of blood vessel walls, and, in severe cases, kidney failure. Most cases of HUS occur after an infection in the digestive system caused by the Escherichia coli bacterium found on contaminated food like meat, dairy products, and juice. The first stages of HUS frequently present with gastrointestinal symptoms such as abdominal pain, vomiting, and bloody diarrhea. This stage lasts from 1 to 15 days. Recovery from this acute colitic phase is the rule. However, more severe problems in the bowel and colon may develop in some cases. (The most vulnerable and severely stricken of children with HUS can die during the first acute stage of the diseasebetween 5 percent and 10 percent.) For most children with HUS, the vomiting and diarrhea stop after 2 or 3 days. Even when the gastroenteritis has stopped, the child does not recover full health, remaining pale, tired, and irritable. The bacteria originally lodged in the digestive system make toxins that enter the bloodstream, and these toxins destroy red blood cells. Small, unexplained bruises or small clot-sized hemorrhages visible in the mucosal lining of the mouth may occur because the toxins also destroy the platelets, cells that normally contribute to the clotting system. The damaged red blood cells and other factors may clog the tiny blood vessels in the kidneys or cause lesions in the kidneys, making the kidneys work harder to remove wastes and extra fluid from the blood. The child may produce little urine as a result. The body's inability to rid itself of excess fluid and waste may in turn cause hypertension or swelling of the hands and feet or may cause generalized fluid accumulation (edema).
Urology Disorders - Hemolytic Uremic Syndrome - Methodist Health Care System - H
hemolytic uremic syndrome, a description, what causes it, possible progression, treatments and statistics for this disease.
http://www.methodisthealth.com/urogen/hemolyt.htm
Lois Joy Galler Foundation For Hemolytic Uremic Syndrome, Inc.
hemolytic uremic syndrome (HUS) is a rare, but very important cause of severe kidney disease in children.
http://www.loisjoygaller.org/hus.htm

Extractions: Fact Sheet and Description of the Hemolytic Uremic Syndrome What is HUS? Hemolytic Uremic Syndrome (HUS) is a rare, but very important cause of severe kidney disease in children. It occurs as infrequently as leukemia in the general population, namely 2-4 new cases/100,000 population/year. These epidemiologic findings would suggest that there are approximately 7,500 children with this disease each year in the United States. However, until HUS is classified as a reportable disease in all 50 states, the exact incidence will remain unknown. HUS ranks among the most common reasons that pediatric patients develop acute kidney failure. In addition, it is a prominent etiology for the development of end stage renal disease, requiring dialysis or kidney transplantation in children. Although permanent renal failure is rare in pediatrics (2-4 new cases/million population/year), HUS is among the top 5 causes of acquired kidney failure. HUS has been diagnosed in countries all around the world, including the United States. Although there are areas that reportedly have a higher incidence of this disease, e.g. Argentina, Holland, South Africa and Southern California, this may represent increased local awareness of the disease. Recent surveys suggest that the number of cases and the severity of the disease may be increasing in North America over the last decade.
Home Page
Atypical HUS, is a rare disease among children causing kidney failure and high blood pressure. Offering support and information including, treatment, symptoms, case studies and research.
http://AtypicalHus.50megs.com
EID V1 N4: Hemolytic Uremic Syndrome
hemolytic uremic syndrome (HUS), commonly referred to as "Hamburger Disease", is a disease that affects the kidneys and
http://www.cdc.gov/ncidod/EID/vol1no4/cameron.htm

Extractions: EID Volume 1 * Number 4 October-December 1995 Commentary Download Article Along with a report of the first outbreak of hemolytic uremic syndrome (HUS) caused by Shiga-like toxin (SLT) producing E. coli in Australia , this issue of Emerging Infectious Diseases presents three papers detailing the investigations of pediatric HUS cases linked to Shiga toxin (ST) and SLT producing bacteria. Goldwater and Bettelheim present a case of pediatric HUS associated with SLT producing Escherichia coli (SLTEC) O48:H21 in South Australia; this strain has not previously been recognized as an SLTEC. Saeed et al. report on the increasingly common identification of HUS in Saudi Arabia, its association with multiple-antibiotic-resistant Shigella dysenteriae type 1, and the inherent dangers of treating such patients with ampicillin and nalidixic acid. Al-Qawari et al. report on the results of active surveillance for dysentery and HUS in Saudi Arabia and discuss a possibly elevated risk for HUS in patients with bloody diarrhea who are hospitalized and treated with nalidixic acid during an outbreak of S. dysenteriae type
WebMD/Lycos - Health Guide
Information about hemolytic uremic syndrome including a definition, causes, incidence, risk factors, symptoms, signs, tests, treatment, prognosis, possible complications and when to call the doctor.
http://webmd.lycos.com/content/asset/adam_disease_hus
Hemolytic Uremic Syndrome
hemolytic uremic syndrome (HUS) is characterized by the acute onset of microangiopathic hemolytic anemia, renal injury, and low platelet count.hemolytic uremic syndrome, POST DIARRHEAL Disease Code 11550 Clinical
http://www.theberries.ca/Archives/HUS.html

Extractions: Hemolytic Uremic Syndrome Hemolytic uremic syndrome (HUS) is a predominantly pediatric condition that consists of the simultaneous triad of hemolytic anemia, thrombocytopenia and acute renal failure. Although uncommon, occurring in approximately 100 children in Canada per year, it is the most common cause of acute renal failure in children and is fatal in a small percentage o children (less than 5%). The recent E. coli epidemic in Walkerton, Ontario and ongoing concern about coliform contamination of water supplies has resulted in discussion of HUS in the media and has raised awareness of HUS in the general public. Timely diagnosis and optimal management require physicians to be knowledgeable about this syndrome and when to suspect HUS. HUS is commonly divided into two groups; those occurring after a diarrheal illness and non-diarrheal HUS. Diarrhea associated HUS is the most common, comprising 75% of all the cases. The most common causative agent is Escherichia coli 0157:H7. Most E.coli 0157 infections result in mild diarrhea but hemorrhagic colitis can occur. HUS occurs in about 10% of children with E.coli 0157:H7 hemorrhagic colitis. Diarrhea associated HUS usually occurs in young children (7 months to 6 years), predominantly in summer and early fall. Sources of contamination include undercooked meat, unpasteurized milk or juice or contaminated water. It can be passed from person to person. Other bacterial diarrheal agents that can cause HUS include Shigella and Salmonellas.
Urology Disorders - Hemolytic Uremic Syndrome - Spanish Content - Methodist Heal
Translate this page El síndrome Urémico Hemolítico ¿Qué es el síndrome urémicohemolítico (su sigla en inglés es HUS)? El síndrome urémico
http://www.methodisthealth.com/spanish/urology/hemolyt.htm
Hemolytic Uremic Syndrome
Date 09Mar-2001 Name hemolytic uremic syndrome Database Medline Set Search Results 001 hemolytic-uremic syndrome/
http://www.up.ac.za/asservices/ais/med/hemolytic.htm

Extractions: Date: 09-Mar-2001 Name: hemolytic uremic syndrome Database: Medline Set Search Results - 001 hemolytic-uremic syndrome/ 546 002 limit 1 to english 456 003 limit 2 to (newborn infant or infant or preschool child or child Unique Identifier 98024821 Authors Horiszny JA. Institution Department of Family Medicine, St. Joseph Hospital, Chicago, IL, USA. Title Index of suspicion. Case 3. Hemolytic-uremic syndrome. Source Pediatrics in Review. 18(11):379, 381-2, 1997 Nov. Abbreviated Source Pediatr Rev. 18(11):379, 381-2, 1997 Nov. Local Messages unidentified < 15 years and 1.8/10(5) children < 5 years. During the prospective study, 122/130 cases were examined for evidence of STEC infection using PCR and/or serological assays and 105 (86%) had evidence of STEC infection. Serum antibodies to E. coli O157 LPS were detected in 79 (67%) cases tested. In conclusion, this study showed that STEC infection is an important cause of HUS in children in France, with a high proportion related to the O157 serogroup. Unique Identifier 20152487 Authors Proulx F. Liet JM. David M. Seidman E. Tapiero B. Robitaille P. Lacroix J. Title Hemolytic uremic syndrome associated with invasive Streptococcus pneumoniae infection [letter; comment]. Source Pediatrics. 105(2):462-3, 2000 Feb. Abbreviated Source Pediatrics. 105(2):462-3, 2000 Feb. Local Messages unidentified
Home Page
Atypical HUS, is a rare disease among children causing kidney failure and high blood pressure. Offering Category Health Conditions and Diseases hemolytic uremic syndrome This site contains information for anyone interested in learning more about thedisease called HUS (hemolytic uremic syndrome) We will show the differences
http://atypicalhus.50megs.com/
What Is HUS?
HAMBURGER DISEASE (Escherichia coli O157H7) hemolytic uremic syndrome (HUS) What is HUS? hemolytic uremic syndrome (HUS) is a disease that affects the kidneys and other organs.
http://www.cheori.org/cpkdrc/what_is_hus.htm

Extractions: H EMOLYTIC U REMIC S YNDROME (HUS) vvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvv What is HUS? Hemolytic Uremic Syndrome (HUS) is a disease that affects the kidneys and other organs. It poses a substantial threat to children as one of the leading causes of sudden acute kidney failure. HUS is most common in the warmer months of the year and follows a gastrointestinal illness caused primarily by a particular strain of bacteria known as Escherichia coli O157:H7. This gastrotintestinal illness has been nicknamed A Hamburger Disease . While other types of E. coli are common in the gastrotintestinal tract of healthy humans, this particular strain (O157:H7) is not usually present. These E. coli O157:H7 bacteria produce extremely potent toxins which are the main cause of the symptoms related to the gastrointestinal illness. The most common symptoms of E. coli O157:H7 gastroenteritis (Hamburger Disease) include: Some individuals may develop fever with this infection. People of all ages can get E. coli
EID V1 N4: Hemolytic Uremic Syndrome
hemolytic uremic syndrome. Download Article Community outbreak of hemolytic uremicsyndrome attributable to Escherichia coli O111NM South Australia, 1995.
http://www.cdc.gov/ncidod/eid/vol1no4/cameron.htm

Extractions: EID Volume 1 * Number 4 October-December 1995 Commentary Download Article Along with a report of the first outbreak of hemolytic uremic syndrome (HUS) caused by Shiga-like toxin (SLT) producing E. coli in Australia , this issue of Emerging Infectious Diseases presents three papers detailing the investigations of pediatric HUS cases linked to Shiga toxin (ST) and SLT producing bacteria. Goldwater and Bettelheim present a case of pediatric HUS associated with SLT producing Escherichia coli (SLTEC) O48:H21 in South Australia; this strain has not previously been recognized as an SLTEC. Saeed et al. report on the increasingly common identification of HUS in Saudi Arabia, its association with multiple-antibiotic-resistant Shigella dysenteriae type 1, and the inherent dangers of treating such patients with ampicillin and nalidixic acid. Al-Qawari et al. report on the results of active surveillance for dysentery and HUS in Saudi Arabia and discuss a possibly elevated risk for HUS in patients with bloody diarrhea who are hospitalized and treated with nalidixic acid during an outbreak of S. dysenteriae type
Hemolytic Uremic Syndrome Due To Shiga-like Toxin Producing Escherichia Coli O48
Dispatches. hemolytic uremic syndrome Due to Shigalike Toxin ProducingEscherichia coli O48H21 in South Australia. Download Article
http://www.cdc.gov/ncidod/eid/vol1no4/goldwat2.htm

Extractions: in South Australia Download Article Enterohemorrhagic Escherichia coli (EHEC) other than serotypes O157:H7 are increasingly recognized in association with hemolytic uremic syndrome (HUS) and have been reported in Australia . While detecting strains of O157:H7 has become easier over the years, identifying the expanding number of other serotypes of EHEC also associated with HUS, with other conditions, and with healthy domestic animals is still very difficult. Cases of HUS have been reported in Australia over a number of years. The most common serotype found was O111:H-, and Australia's recently reported first HUS outbreak was caused by EHEC O111:H-. We wish to report a case of severe HUS due to serotype O48:H21, which, as far as we know, has not been previously reported as a cause of HUS. This case occurred in 1993, before surveillance of HUS had been initiated; after this case, between July and December 1994, 10 cases of HUS (from which four isolates were obtained; two were EHEC O111) were reported to the Australian Paediatric Surveillance Unit (E. Elliott, pers. comm.). /L to 47 x 10 /L on these dates, respectively. The blood film showed microangiopathic hemolytic anemia with fragmented red cells. She required hemodialysis for 3 weeks and was discharged from the hospital on 31 January 1994.
Hemolytic Uremic Syndrome - Urological Disorders Health Guide
Urological Disorders. hemolytic uremic syndrome. What is hemolytic uremicsyndrome (HUS)? hemolytic uremic syndrome is a rare condition
http://www.umm.edu/urology-info/hemolyt.htm

Extractions: The first stage of HUS frequently lasts from 1 to 15 days and may include gastrointestinal symptoms such as: Severe problems in the bowel and colon may develop in some cases. In these cases, even if the gastroenteritis has stopped, a child may still exhibit the following symptoms: irritability fatigue small, unexplained bruises or small clot-sized hemorrhages visible in the mucosal lining of the mouth
Hemolytic Uremic Syndrome
hemolytic uremic syndrome. 2000 COl VI No. 135; Stewart CL and Tina LU. Hemolyticuremic syndrome. Pediatrics in review 1993;14(6)218-224; Moghal NE.
http://www.theberries.ns.ca/Archives/HUS.html

Extractions: Hemolytic Uremic Syndrome Hemolytic uremic syndrome (HUS) is a predominantly pediatric condition that consists of the simultaneous triad of hemolytic anemia, thrombocytopenia and acute renal failure. Although uncommon, occurring in approximately 100 children in Canada per year, it is the most common cause of acute renal failure in children and is fatal in a small percentage o children (less than 5%). The recent E. coli epidemic in Walkerton, Ontario and ongoing concern about coliform contamination of water supplies has resulted in discussion of HUS in the media and has raised awareness of HUS in the general public. Timely diagnosis and optimal management require physicians to be knowledgeable about this syndrome and when to suspect HUS. HUS is commonly divided into two groups; those occurring after a diarrheal illness and non-diarrheal HUS. Diarrhea associated HUS is the most common, comprising 75% of all the cases. The most common causative agent is Escherichia coli 0157:H7. Most E.coli 0157 infections result in mild diarrhea but hemorrhagic colitis can occur. HUS occurs in about 10% of children with E.coli 0157:H7 hemorrhagic colitis. Diarrhea associated HUS usually occurs in young children (7 months to 6 years), predominantly in summer and early fall. Sources of contamination include undercooked meat, unpasteurized milk or juice or contaminated water. It can be passed from person to person. Other bacterial diarrheal agents that can cause HUS include Shigella and Salmonellas.
Hemolytic-Uremic Syndrome
HemolyticUremic Syndrome hemolytic uremic syndrome. Book, Home Page.
http://www.fpnotebook.com/HEM62.htm

Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Hematology and Oncology Infectious Disease Laboratory ... Platelet Hemolytic-Uremic Syndrome Hemolytic-Uremic Syndrome Hemolytic Uremic Syndrome Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hematology and Oncology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Surgery Symptom Evaluation Vascular Page Infectious Disease Index Lab Neutropenia Platelet HUS Pathophysiology Associated with Escherichia coli 0157:H7 infection Verocytotoxin induces endothelial injury Fibrin deposited in renal microvasculature Red Blood Cell destruction Platelet destruction, consumption, sequestration
Hemolytic Uremic Syndrome
hemolytic uremic syndrome is a rare condition affecting mostly childrenunder the age of 10. Subscribe now . hemolytic uremic syndrome.
http://healthlink.mcw.edu/article/943053875.html

Extractions: Subscribe now >> Hemolytic (HEE-mo-LIT-ik) uremic (yoo-REE-mik) syndrome is a rare condition affecting mostly children under the age of 10. Hemolytic uremic syndrome (HUS) is characterized by destruction of red blood cells, damage to the lining of blood vessel walls, and, in severe cases, kidney failure. Most cases of HUS occur after an infection in the digestive system caused by the E. coli bacterium found on contaminated food like meat, dairy products, and juice. The first stages of HUS frequently present with gastrointestinal symptoms such as abdominal pain, vomiting, and bloody diarrhea. This stage lasts from 1 to 15 days. Recovery from this acute colitic phase is the rule. However, more severe problems in the bowel and colon may develop in some cases. (The most vulnerable and severely stricken of children with HUS can die during the first acute stage of the diseasebetween 5 percent and 10 percent.) For most children with HUS, the vomiting and diarrhea stop after 2 or 3 days. Even when the gastroenteritis has stopped, the child does not recover full health, remaining pale, tired, and irritable. The bacteria originally lodged in the digestive system make toxins that enter the bloodstream, and these toxins destroy red blood cells. Small, unexplained bruises or small clot-sized hemorrhages visible in the mucosal lining of the mouth may occur because the toxins also destroy the platelets, cells that normally contribute to the clotting system.

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