LMBBS Home Page Information for health-care professionals involved in the care of Laurence-Moon-Bardet-Biedl Syndrome Category Health Conditions and Diseases Bardet-Biedl Syndrome laurencemoon syndrome (LMS) is characterised by retinitis pigmentosa (more accuratelytermed rod-cone dystrophy), mental retardation, hypogenitalism and http://www.isgrd.umds.ac.uk/laurence/
Extractions: Laurence-Moon-Bardet-Biedl Syndrome (LMBBS) This page is aimed primarily at medical and health-care professionals involved in the care of LMBBS patients and also for parents or relatives wishing to know more about the syndrome and the implications for those affected. CONTENTS HISTORY rod-cone dystrophy ), mental retardation, hypogenitalism and spastic paraparesis. Bardet-Biedl syndrome (BBS) has as the main features RP (rod-cone dystrophy), obesity, postaxial polydactyly, learning disabilities and hypogenitalism (males). This latter subgroup represents by far the majority of published cases and is now the preferred term amongst the medical and scientific community. As there are many cases of overlap between the LMS and BBS we shall for the purposes of this publication make no distinction and therefore refer to LMBBS throughout. John Zachariah Laurence c.1870
Pediatric Database A definition of laurencemoon syndrome followed by the epidemiology, pathogenesis, clinical features, investigations and management. http://www.icondata.com/health/pedbase/files/LAURENCE.HTM
Extractions: Pediatric Database (PEDBASE) Discipline: GEN Last Updated: 12/23/94 A genetic disorder of unknown etiology characterized by progressive neurological, ophthalmologic, and endocrine manifestations resulting in a deteriorating handicapping condition. risk factors: M = F Arab population of Kuwait 1. Hypogonadotrophic Hypogonadism
Laurence Moon Bardet Biedl Syndrome laurencemoon syndrome, Pediatric Database (PEDBASE); Laurence-Moon-Bardet-Biedl(LMBB), Senter for sjeldne sykdommer og syndromer Smågruppesenteret på http://www.kumc.edu/gec/support/laurmoon.html
Laurence-Moon Syndrome Syndrome. laurencemoon syndrome. Summary. A syndrome of mental retardation, retinitis pigmentosa, hypogonadism, and http://www.nlm.nih.gov/mesh/jablonski/syndromes/syndrome393.html
Extractions: Syndrome Laurence-Moon syndrome Summary A syndrome of mental retardation, retinitis pigmentosa, hypogonadism, and spastic paraplegia. Laurence-Moon-Biedl syndrome and Laurence-Moon-Biedl-Bardet syndrome are no longer considered as valid terms in that patients with Laurence and Moon had spastic paraplegia but no polydactyly and obesity which were the key elements in the Bardet and Biedl patients. Bardet-Biedl syndrome is a separate entity. Major Features Eyes: Pigmentary retinopathy. Nervous system: Spastic paraplegia. Urogenital system: Hypogonadism. Growth and development: Mental retardation. Heredity: The syndrome is familial and is transmitted as an autosomal recessive trait.
Laurence-Moon-Bardet-Biedl Syndrome NORD Laurence Moon Syndrome laurence-moon syndrome is a rare inherited disorder characterized by diminished hormone http://www.familyvillage.wisc.edu/lib_lmbb.htm
National Library Of Medicine A look at the former names of laurencemoon syndrome, a summary and a list of clinical features. http://www.nlm.nih.gov/cgi/jablonski/syndrome_cgi?term=Laurence-Moon syndrome&am
Health Library - Laurence Moon Syndrome Laurence Moon Syndrome. Confusion exists in the medical literature regardingthe difference between laurencemoon syndrome and Bardet-Biedl Syndrome. http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=
Health Library - Laurence Moon Syndrome Laurence Moon Syndrome. Confusion exists in the medical literature regardingthe difference between laurencemoon syndrome and Bardet-Biedl Syndrome. http://www.laurushealth.com/library/healthguide/illnessconditions/topic.asp?hwid
Laurence Moon/Bardet Biedl Syndrome NORD Laurence Moon Syndrome laurence-moon syndrome is a rare inherited disordercharacterized by diminished hormone production by the testes or ovaries http://www.lowvision.org/laurence_moon.htm
Extractions: LMBBS Home page This page is aimed primarily at medical and health-care professionals involved in the care of LMBBS patients and also for parents or relatives wishing to know more about the syndrome and the implications for those affected. NORD - Laurence Moon Syndrome Laurence-Moon Syndrome is a rare inherited disorder characterized by diminished hormone production by the testes or ovaries (hypogonadism), progressive loss of vision (retinitis pigmentosa), mental retardation, and paralysis of the legs and lower part of the body accompanied by involuntary muscle contractions (spastic paraplegia). LMBBS Home page This page is aimed primarily at medical and health-care professionals involved in the care of LMBBS patients and also for parents or relatives wishing to know more about the syndrome and the implications for those affected.
ORPHANET® : Laurence-Moon Syndrome Translate this page ORPHANET. ORPHANET database access. laurence-moon syndrome.Direct access to details Alias Home Page. http://www.orpha.net/static/GB/laurence_moon.html
Service Page - Pathologie Information DISEASE laurencemoon syndrome, CIM Q87.8, laurence-moon syndrome is more frequentin the Arab population of Kuwait. * author S. Aymé MD (September. 2001) *, http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=2377
Bardet-Biedl Syndrome (BBS) A summary of Bardet-Biedl syndrome and a list of major features.Category Health Conditions and Diseases Bardet-Biedl Syndrome syndrome. laurencemoon syndrome is a separate entity. Major Features,Eyes Pigmentary retinopathy. Hand and foot Polydactyly. http://www.nlm.nih.gov/mesh/jablonski/syndromes/syndrome048.html
Extractions: Syndrome Bardet-Biedl syndrome (BBS) Summary A syndrome characterized mainly by obesity, pigmentary retinopathy, polydactyly, mental retardation, hypogonadism, and renal failure in fatal cases. Two forms have been identified: Bardet-Biedl syndrome 1 (BBS1) has no linkage to chromosome 16 Bardet-Biedl syndrome 2 (BBS2) is mapped to markers on chromosome 16. Laurence-Moon-Biedl syndrome and Laurence-Moon-Biedl-Bardet syndrome are no longer considered as valid terms in that patients of Laurence and Moon had paraplegia but no polydactyly and obesity which are the key elements of the Bardet-Biedl the syndrome. Laurence-Moon syndrome is a separate entity. Major Features Eyes: Pigmentary retinopathy. Hand and foot: Polydactyly. Cardiovascular system: Hypertrophy of interventricular septum and left ventricle and dilated cardiomyopathy. Gastrointestinal system: Fibrosis. Urogenital system: Hypogonadism, renal failure, urogenital sinuses, ectopic urethra, uterus duplex, septate vagina, and hypoplasia of the uterus, ovaries, and fallopian tubes. Growth and development: Mental and growth retardation.
Laurence-Moon Bardet-Biedel Syndrome - Foundation Fighting Blindness BardetBiedel syndrome is often confused with laurence-moon syndrome. Laurence-Moonsyndrome is extremely rare; only a few case have been documented. http://www.blindness.org/laurence-moon-bardet-biedel-syndrome.asp
Extractions: Stargardt Disease ... Bardet-Biedel syndrome is often referred to as Laurence-Moon Bardet-Biedel syndrome (correctly spelled Laurence-Moon Bardet Biedl ) or Laurence-Moon/Biedel syndrome. Bardet-Biedel syndrome is often confused with Laurence-Moon syndrome. Individuals with Laurence-Moon syndrome almost always experience neurologic problems but rarely polydactyly. Polydactyly is a defining feature of Bardet-Biedel syndrome, while neurologic problems almost never occur. Laurence-Moon syndrome is extremely rare; only a few case have been documented. Because of the similarity of these syndromes, Bardet-Biedel syndrome is often referred to as Laurence-Moon Bardet-Biedel syndrome or Laurence-Moon/Biedel syndrome. The Foundation Fighting Blindness is a research foundation dedicated to finding the causes, treatments and cures for retinitis pigmentosa (RP), Usher syndrome, macular degeneration and other rare retinal degenerative diseases like Laurence-Moon Bardet-Biedel syndrome
NORD - National Organization For Rare Disorders, Inc. Confusion exists in the medical literature regarding the differencebetween BardetBiedl Syndrome and laurence-moon syndrome. . http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Bardet Biedl
Débats Listesnof : Syndrome De Laurence-Moon-Bardet-Biedl Translate this page but that the patients of Laurence and Moon had a distinct disorder with paraplegiaand without polydactyly and obesity (see laurence-moon syndrome, 245800). http://g5d.chez.tiscali.fr/COCNet10/COCMED10/lsnofLBB.htm
Extractions: sommaire Syndrome de Laurence-Moon-Bardet-Biedl Chers Amis Un conseil : http://www.healthgate.com/HealthGate/home.html Yannick LE MER Amicalement Chantal NOVEL Xavier ZANLONGHI Voir E.M.C. Ophtalmologie 21470 A 50, Les syndromes oculo-auditifs, page 12 Cordialement Georges LAROCHE Marc Abitbol avait fait une remarquable mise au point sur ces syndromes. Pourrait-il nous la redonner? ou notre webmaster? Alain BRON *209900 BARDET- BIEDL SYNDROME, TEXT This condition is characterized by mental retardation, pigmentary retinopathy, polydactyly, obesity, and hypogenitalism, and has incorrectly been called LMBB (Laurence-Moon-Bardet-Biedl) syndrome. Ammann (1970) pointed out that these features were present in the patients of Biedl (1922) and Bardet (1920), but that the patients of Laurence and Moon had a distinct disorder with paraplegia and without polydactyly and obesity (see Laurence-Moon syndrome, 245800). As indicated by Ammann's study, residual heterogeneity may exist even after the Laurence-Moon syndrome is separated. In Bedouin families in the Negev region of Israel, presumably the same kindreds as those studied by Kwitek-Black et al. (1993), Elbedour et al. (1994) performed echocardiographic evaluations of cardiac involvement in BBS. They stated that they found cardiac involvement in 50% of cases, justifying inclusion of echocardiographic examination in the clinical evaluation and follow-up of these patients. However, their table 1 gives echocardiographic abnormality in only 7 of 22 cases and these included 1 case of bicuspid aortic valve, 1 case of mild thickening of the interventricular septum, 1 case of 'moderate tricuspid regurgitation,' and 1 case of mild pulmonic valve stenosis. The occurrence of renal abnormality in 11 of the 22 patients on kidney ultrasonography was somewhat more impressive than the cardiac involvement.
Laurence-Moon Syndrome : Meddie Health Search Rate It. Pediatric Database A definition of laurencemoon syndrome followed by theepidemiology, pathogenesis, clinical features, investigations and management. http://www.meddie.com/search/Health/Conditions_and_Diseases/Genetic_Disorders/La
Bardet-Biedl Laurence-Moon Syndroom/History The estimates for laurencemoon syndrome are much lower still. Learning disabilities.laurence-moon syndrome. * Spasticity (often progressive) or ataxia. http://www.angelfire.com/co3/PEKICH/BBLMS_history.html
Extractions: T h e Bardet-Biedl and Laurence-Moon syndromes are two uncommon disorders. Both syndromes are genetic, that is, caused by altered genes, and occur throughout the world, equally in men and in women. Historically these conditions were so similar that for some time they had been considered the same disorder. However, in the past few years, it has become apparent that these are two separate and distinct syndromes Brief history I n 1866 doctors Laurence and Moon in England described four members of the same family who had retinal problems, unsteady gait and spinal cord problems, and developmental delays. In the 1920s Doctors Bardet (in France) and Biedl (in Germany) independently published articles describing patients with extra fingers and toes at birth, infantile obesity, and retinal disorders. The similarities of the signs in these patients were so striking that it was decided to adopt the suggestion to speak of these as one syndrome: Laurence-Moon/Bardet-Biedl Syndrome.
LAURENCE-MOON SYNDROME laurencemoon syndrome - A syndrome of mental retardation, pigmentary retinopathy,hypogenitalism, and spastic paraplegia; transmitted with a autosomal http://www.mymedadvice.com/html/5/gls_2868.htm
Health Library - Laurence Moon Syndrome Search. Laurence Moon Syndrome. Confusion exists in the medical literature regardingthe difference between laurencemoon syndrome and Bardet-Biedl Syndrome. http://yourhealth.stlukesonline.org/Library/HealthGuide/IllnessConditions/topic.
