Geometry.Net - Health_Conditions: Leishmaniasis

OneWorld Health :: South America
Information about Chagas Disease, Visceral leishmaniasis and Cutaneous leishmaniasis by The Institute for One World Health.
http://www.oneworldhealth.org/geography/southamerica.html
Mundo Sano
Informaci³n sobre diversas enfermedades transmisibles leishmaniasis, hantavirus , SIDA/HIV, Chagas, dengue, clamidiasis, malaria, paludismo, leptospirosis, salmonelosis, fiebre hemorr¡gica, estrogiloidiasis, criptococosis y borreliosis de Lyme.
http://www.mundosano.org/
The JI -- Abstracts: Stäger Et Al. 165 (12): 7064
Simona St¤ger, Deborah F. Smith and Paul M. Kaye. Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. Journal of Immunology.
http://www.jimmunol.org/cgi/content/abstract/165/12/7064

Extractions: The American Association of Immunologists Deborah F. Smith and Paul M. Kaye Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; and Wellcome Trust Laboratories for Molecular Parasitology, Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, United Kingdom Vaccination against visceral leishmaniasis has received limited attention compared with cutaneous leishmaniasis, although the need for an effective vaccine against visceral leishmaniasis is pressing. In this study, we demonstrate for the first time that a recombinant
Leishmaniasis - Page 2
Clinical Features Human leishmanial infections can result in 2 main forms ofdisease, cutaneous leishmaniasis and visceral leishmaniasis (kalaazar).
http://www.dpd.cdc.gov/dpdx/HTML/Frames/G-L/Leishmaniasis/body_Leishmaniasis_pag

Extractions: Human leishmanial infections can result in 2 main forms of disease, cutaneous leishmaniasis and visceral leishmaniasis (kala-azar). The factors determining the form of disease include leishmanial species, geographic location, and immune response of the host. Cutaneous leishmaniasis is characterized by one or more cutaneous lesions on areas where sandflies have fed. Persons who have cutaneous leishmaniasis have one or more sores on their skin. The sores can change in size and appearance over time. They often end up looking somewhat like a volcano, with a raised edge and central crater. A scab covers some sores. The sores can be painless or painful. Some people have swollen glands near the sores (for example, in the armpit if the sores are on the arm or hand). Persons who have visceral leishmaniasis usually have fever, weight loss, and an enlarged spleen and liver (usually the spleen is bigger than the liver). Some patients have swollen glands. Certain blood tests are abnormal. For example, patients usually have low blood counts, including a low red blood cell count (anemia), low white blood cell count, and low platelet count. Some patients develop post kala-azar dermal leishmaniasis. Visceral leishmaniasis is becoming an important opportunistic infection in areas where it coexists with HIV. Laboratory Diagnosis:
Leishmaniasis, All About
Abstract, introduction, clinical manifestations, diagnosis and differential, ecology, treatment and control, drugs. From Medscape.
http://www.medscape.com/SCP/IIM/1999/v16.n09/m1609.08.god/m1609.08.god-01.html
Index Of /2738m
Introduction, morphology, transmission, immunology, and treatment. From the University of East London, B.Sc Applied Biology course project.
http://homepages.uel.ac.uk/2738m/
EMedicine - Leishmaniasis : Article By Conjivaram Vidyashankar, MD
leishmaniasis leishmaniasis is a zoonotic infection caused by the protozoa belongingto the genus Leishmania. leishmaniasis. Last Updated July 8, 2002,
http://www.emedicine.com/ped/topic1292.htm

Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Parasitology Last Updated: July 8, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: kala azar, black fever, Dumdum fever, Assam fever, infants splenomegaly, infantile splenomegaly, cutaneous leishmaniasis, mucocutaneous leishmaniasis, visceral leishmaniasis, VL AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Conjivaram Vidyashankar, MD , Consulting Staff, Department of Pediatrics, Military Hospital, Namkum, Ranchi, India Coauthor(s): Ruchir Agrawal, MD , Department of Allergy and Immunology, Louisiana State University Health Sciences Center at Shreveport Editor(s): Gary J Noel, MD , Clinical Associate Professor, Department of Pediatrics, Weill Medical College of Cornell University; Mary L Windle, PharmD , Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy;
Treatment Of Leishmaniasis
Treatment of leishmaniasis. Classical treatment For the treatmentof leishmaniasis the currently used drugs are limited to four.
http://www.icp.ucl.ac.be/~opperd/parasites/leish5.htm

Extractions: For the treatment of Leishmaniasis the currently used drugs are limited to four. The first line compounds are the two pentavalent antimonials, sodium stibogluconate ( Pentostam ) and meglumine antimoniate ( Glucantime ). They have been used for the first time in 1947 and 1950, respectively. These drugs are administered parenterally at a dosage of 10-20 mg and respectively 28 Sb/kg per day for 10 to 30 days. Failures and relapses occur in all forms of leishmaniasis and constitute approximately 10-25% of cases. If these drugs are not effective, the second line compounds of pentamidine Lomidine ) and amphotericine B ( Fungizone ) are used, which have been introduced in 1940 and 1959, respectively. No new drugs have been developed recently although some experimental drugs are going through clinical trials. These are: Allopurinol , a drug in use for the treatment of gout. It is supposed to function as an alternative substrate for the enzyme hypoxanthine guanine phosphoribosyl transferase (HGPRTase), so allowing the incorporation of allopurinol riboside into RNA, which leads to the inhibition of protein synthesis in the parasite. It is also on trial for the treatment of Chagas'disease and the drug is now widely used for the treatment of leishmaniasis in dogs.
Leishmaniasis
leishmaniasis. 24/10/01. Click here to start. Table of Contents. leishmaniasis.Lecture Topics. Introduction. The Parasite. Morphology. Morphology.
http://homepages.uel.ac.uk/d.p.humber/powerpoint/leishmaniasis/
MSF Access Website | The Campaign | Target Diseases | Leishmaniasis
leishmaniasis is an old but largely unknown disease. Some facts about leishmaniasisAround 2 million people become ill with leishmaniasis every year.
http://www.accessmed-msf.org/campaign/lsh01.shtm

Extractions: The forgotten disease Leishmaniasis is an old but largely unknown disease. It has a long history. Indeed, it has been present in the Americas and in Africa for several centuries. In countries where insecticide spraying was widely used to control malaria in the 1950s, such as Bangladesh and Nepal, kala-azar virtually disappeared. In the 1970s, after the insecticide campaigns ceased, the disease made a significant comeback. One of the largest kala-azar epidemics ever documented occurred in 1978 in India (North Bihar) where over half a million people died. Today, this disease affects 12 million people in 88 countries. The majority of cases are in developing countries, especially in the poorest and most remote communities, among populations that are neglected by their governments and by the outside world. Unacknowledged and uncontrolled, this treatable disease continues to claim lives in remote areas. The parasite is transmitted by a sand fly living in tropical and temperate regions. The disease affects animals such as rodents and dogs, as well as humans. In humans the disease exists in different forms depending on the type of parasite and the immunity of the infected person. Thus it may present as simple skin ulcers, or in a progressive form that may permanently disfigure those infected, or as visceral leishmaniasis which invades the whole body. Some facts about leishmaniasis: Around 2 million people become ill with leishmaniasis every year. Only 30 per cent of this number are officially reported.
Leishmaniasis - 1
Dept. of Dermatology University of Iowa College of Medicine. leishmaniasis- Anterior Tibia. Return to Image Index page. Return to Image Index page.
http://tray.dermatology.uiowa.edu/Leish001.htm
Reprinted With Permission Of Clinical Infectious Diseases
Includes leishmaniasis as one of the diseases studied in connection with Operations Desert Shield/Desert Storm. From Office of the Special Assistant for Gulf War Illnesses, reprinted from Clinical Infectious Diseases.
http://www.gulflink.osd.mil/medical/med_impact.htm

Extractions: An assessment was conducted of the impact of infectious diseases on the 697,000 U.S. troops deployed to the Persian Gulf during 1990-1991 in Operations Desert Shield and Desert Storm. The incidence of nonbattle injuries, including infectious diseases, during this conflict was lower than during previous wars involving U.S. military personnel. The major reported causes of morbidity were generally mild cases of acute diarrheal and upper respiratory disease. The most unexpected outcome was the lack of arboviral infections, particularly sandfly fever, and the occurrence among U.S. troops of 12 cases of visceral leishmaniasis due to
Cost B9
leishmaniasis seminar in Bruges, Belgium on 2931 May 2000 sponsored by COST-B9 (European Cooperation in the field of Scientific and Technical Research).
http://www.icp.ucl.ac.be/cost/
SBRI: Leishmaniasis
leishmaniasis. Impact leishmaniasis is a parasitic disease transmitted bythe bite of a sandfly that is infected with Leishmania parasites.
http://www.sbri.org/mission/disease/leishmania.asp

Extractions: Workshop Impact Leishmaniasis is a parasitic disease transmitted by the bite of a sandfly that is infected with Leishmania parasites. Currently 350 million people in 88 countries around the world are threatened and 12 million people are thought to be affected by leishmaniasis. Of the 1.5 2 million new cases of leishmaniasis estimated to occur annually, most occur in the tropics and subtropics. Leishmania /HIV co-infection is emerging as a serious new disease and it is increasingly frequent. It is considered a real threat in south-western Europe, such as Spain, Italy, France, and Portugal. (WHO/TDR/Stammers) Symptoms With the bite of an infected sandfly, Leishmania parasites are passed from one infected animal or human to others. Leishmaniasis is a spectrum of diseases, each distinctly manifested and all with potentially devastating consequences-disfigurement, damage to internal organs, death. In tandem with the steady rise in leishmaniasis is the increasing risk of co-infection in people with HIV/AIDS. Depending on the species of the infecting parasite, the spleen, liver, bone marrow, mucous membranes, and/or skin may be attacked. Leishmania donovani
Worldleish
Official site of the World Congress of leishmaniasis. Includes meeting information and news.
http://www.worldleish.org/
Leishmaniasis
Translate this page Atrás leishmaniasis La leishmaniasis es una enfermedad infecciosa provocadapor un parásito denominado leishmania. Según la Organización
http://www.ondasalud.com/edicion/noticia/0,2458,23343,00.html
LEISHMANIASIS
Translate this page leishmaniasis. Definición Infección con una especie de Leishmania.Inglés leishmaniasis. Francés LEISHMANIOSE. Ver también
http://www.popin.org/~unpopterms/files/data/esp01285.htm
LEISHMANIASIS
leishmaniasis. Definition Infection with a species of Leishmania. Spanishleishmaniasis. French LEISHMANIOSE. See also PARASITIC DISEASES.
http://www.popin.org/~unpopterms/files/data/eng01166.htm
Leishmaniasis
leishmaniasis. leishmaniasis Visceral leishmaniasis has emerged as a major coinfectionin people with HIV/AIDS in some regions of the world. Cutaneous
http://www.niaid.nih.gov/newsroom/focuson/bugborne01/leish.htm

Extractions: Leishmaniasis, any of several diseases caused by single-celled parasites of the genus Leishmania , is spread to humans through the bite of the sandfly. About 12 million people are infected with Leishmania species worldwide, but it is rare in the United States. The parasite has infected large numbers of foxhounds in this country, however, causing health officials to closely monitor the disease to assess the risk of transmission to people. Visceral leishmaniasis, an infection of the internal organs, may produce fever, weight loss, anemia, and enlarged liver or spleen, or it may cause no symptoms. The disease is usually fatal if untreated. Visceral leishmaniasis has emerged as a major coinfection in people with HIV/AIDS in some regions of the world.
Component Of Fly Saliva Makes Promising Leishmaniasis Vaccine
Component of Fly Saliva Makes Promising leishmaniasis Vaccine Researchers seekingto make a vaccine against a serious parasitic infection have discovered a
http://www.niaid.nih.gov/newsroom/releases/leishvacc.htm

Extractions: Researchers seeking to make a vaccine against a serious parasitic infection have discovered a dose of fly saliva might be just what the doctor ordered. Leishmaniasis, a disabling and sometimes deadly tropical illness, is caused by a parasite transmitted to people through the bite of a sand fly. In a report released today, scientists from the National Institute of Allergy and Infectious Diseases (NIAID) describe how a vaccine they developed against a component of sand fly saliva prevents leishmaniasis in mice. Leishmaniasis, a major health problem in many tropical and desert climates, has resisted efforts to develop an effective vaccine. "Today's report describes a novel vaccine," says NIAID Director Anthony S. Fauci, M.D. "Rather than targeting the parasite, as is typical, our researchers produced a vaccine to the saliva of the insect that transmits the parasite. This approach could potentially be used to develop vaccines for other insect- or tick-borne diseases."

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