Lipoid Nephrosis Subject lipoid nephrosis Topic Area Urology General Forum The UrologyForum Question Posted By Mieke on Friday, February 20, 1998 . http://www.medhelp.org/perl6/urology/archive/175.html
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: NS, nephrosis, lipoid nephrosis, primary nephrotic syndrome, PNS, idiopathic nephrotic syndrome, INS, secondary nephrotic syndrome, minimal change nephrotic syndrome, MCNS, minimal lesion nephrotic syndrome, MLNS, nil disease, steroid-sensitive nephrotic syndrome, SSNS, steroid-resistant nephrotic syndrome, SRNS, steroid-dependent nephrotic syndrome, SDNS, mesangial proliferative glomerulonephritis, MPN, immunoglobulin M nephropathy, focal segmental glomerulosclerosis, FSGS, membranoproliferative or mesangiocapillary glomerulonephritis, MPGN, hypocomplementemic glomerulonephritis, membranous glomerulonephritis, MGN, congenital nephrotic syndrome Background: The word nephrosis, or what often is called primary nephrotic syndrome (PNS), has its origin in the early part of the 20th century. Nephrosis describes a clinical condition of edema and proteinuria characterized morphologically (light microscopy [LM]) by fatty degeneration of the renal tubules associated with normal glomeruli. The term nephrosis was introduced primarily to distinguish it from nephritis, a term used to denote the clinical condition associated with cellular proliferation of the glomerulus. Shortly thereafter the name of the condition was changed to lipoid nephrosis when it was noted that lipid droplets commonly were found in the urine of affected patients. Lipoid nephrosis gradually evolved to the present name of nephrotic syndrome (NS).
THE MERCK MANUAL, Sec. 17, Ch. 224, Glomerular Diseases An in depth look at nephrotic syndrome as well as lipoid nephrosis, focal segmental gomeruloscleroses, HIVassociated nephropathy, and membranous glomerulonephritis. http://www.merck.com/pubs/mmanual/section17/chapter224/224c.htm
Extractions: This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 17. Genitourinary Disorders Chapter 224. Glomerular Diseases Topics [General] Nephritic Syndrome Nephrotic Syndrome Nephrotic Syndrome A predictable complex that results from a severe, prolonged increase in glomerular permeability for protein. Etiology and Classification Nephrotic syndrome (NS) occurs at any age but is more prevalent in children than in adults; in children, it is most common between ages 1 1/2 and 4 yr. There is a predilection for young males, but the sex distribution in older patients is more equal. Proteinuria is thought to occur through functional derangement of two mechanisms: the size-selective barrier leaks large protein molecules, and the charge-selective barrier fails to retain lower mol wt proteins. Diseases causing NS are listed in Table 224-7. Primary causes include minimal change disease, focal segmental glomerulosclerosis (FSGS), membranous glomerulonephritis (MGN), membranoproliferative glomerulonephritis (MPGN), and mesangial proliferative glomerulonephritis (GN). NS can also be due to secondary causes. Symptoms and Signs An early sign of NS is frothy urine due to protein. Other features include anorexia, malaise, puffy eyelids, retinal sheen, abdominal pain, and wasting of muscles. Anasarca with ascites and pleural effusions may occur.
Extractions: During the sixteenth to the mid-eighteenth century the general view was that"dropsy" was a disorder per se, one of the many types of swellings, local and general: physicians did not ask themselves what the "cause" of a dropsy might be; the patient "had" a dropsy. Thus when Samuel Johnson died dropsical in 1784 there was no speculation as to its "origin", and the fact that his kidneys were grossly diseased was noted only incidentally at the post mortem. This contemporary attitude to dropsy makes the observations of the early paediatrician Theodor Zwinger (1658-1724) of Basel, Switzerland in 1722 all the more remarkable, in that he unequivocally attributed the condition to disease in the renal tubules [1,2] since in paediatric practice, liver and heart disease would rarely have been present as causes of generalised edema.
Lipoid Nephrosis lipoid nephrosis. Nephrotic syndrome. Electron micrograph.Previous Next 1 2 3 4 5 Return to Systemic Pathology Page. http://biomed.brown.edu/Courses/BI279/Lec09/Lec09-D.htm
072ALipoid Nephrosis (low) lipoid nephrosis (low) Glomeruli are normal on light microscopic examination capillary loops are open with delicate walls, the mesangium is not hypercellular ( no more than 3 mesangial cells between capillaries ) or expanded. http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072A.html
Extractions: Lipoid Nephrosis (low) Glomeruli are normal on light microscopic examination - capillary loops are open with delicate walls, the mesangium is not hypercellular ( no more than 3 mesangial cells between capillaries ) or expanded. click here to see a larger version of this image in a new browser window. Johns Hopkins School Of Medicine Department of Pathology
072BLipoid Nephrosis (high) lipoid nephrosis (high) Proximal tubular cells show fine vacuolisation ( bubbly cytoplasm ) these are lipid droplets, reflecting lipiduria which in turn is secondary to hyperlipidemia. http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072B.html
Extractions: Lipoid Nephrosis (high) Proximal tubular cells show fine vacuolisation ( bubbly cytoplasm ) -these are lipid droplets, reflecting lipiduria which in turn is secondary to hyperlipidemia. click here to see a larger version of this image in a new browser window. Johns Hopkins School Of Medicine Department of Pathology
Lipoid Nephrosis Subject lipoid nephrosis Forum The Urology Forum Topic Area Postedby Mieke on February 20, 1998 at 041109 Is lipoid nephrosis http://www.medhelp.org/perl6/urology/archive/146.html
Extractions: The Urology Forum Urology Forum Archives Med Help Home Information contained within this forum is intended solely for general educational purposes and is not intended nor implied to be a substitute for professional medical advice relative to your specific medical condition or question. Always seek the advice of your physician or other health provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this site you agree to the following Terms and Conditions Med Help International
Lipoid Nephrosis Medical Encyclopdia article about lipoid nephrosis A resource with information on over 4000 medical topics including lipoid nephrosis http://www.marylandadd.com/medical-terms/01322.htm
Lipoid Nephrosis - General Practice Notebook lipoid nephrosis. Minimal change nephropathy is responsible for 90% ofthe cases of nephrotic syndrome in children less than 5 years of age. http://www.gpnotebook.co.uk/cache/355794967.htm
Extractions: lipoid nephrosis Minimal change nephropathy is responsible for 90% of the cases of nephrotic syndrome in children less than 5 years of age. It also occurs in adults - approx 20%. The name is derived from the fact that the only detectable abnormality histologically is fusion and deformity of the foot processes under the electron microscope. Both light microscopy and immunofluorescence are unremarkable. The condition is most frequent in children aged between two and four years. It has been suggested that MCD is more common in atopic patients, especially those posessing HLA-DR7. However, a direct link between allergic sensitisation and the onset of MCD is yet to be established. MCD is steroid-responsive and, in general, does not lead to chronic renal failure.
LIPOID NEPHROSIS lipoid nephrosis A disorder of the kidneys which largely affectsthe glomerulus, the blood filtering structure. This disorder http://www.mymedadvice.com/html/5/gls_2920.htm
Extractions: LIPOID NEPHROSIS - A disorder of the kidneys which largely affects the glomerulus , the blood filtering structure. This disorder is one common cause of nephrotic syndrome in children affecting 2 to 3 children per 100,000 population under age 16 in the US. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. Risk factors include a history for a immune disorder, recent immunization, or a bee sting. Diagnosis is made by renal biopsy . Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented.
Lipoid Nephrosis The Urology Forum ask the doctor medical forum for patients hosted by Med Help Intl. Is lipoid nephrosis just an older name for minimal change disease? http://www.medhelp.org/forums/urology/archive/146.html
Extractions: The Urology Forum Urology Forum Archives Med Help Home Information contained within this forum is intended solely for general educational purposes and is not intended nor implied to be a substitute for professional medical advice relative to your specific medical condition or question. Always seek the advice of your physician or other health provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this site you agree to the following Terms and Conditions Med Help International
DSHI Systems - Medical Glossary LIGAMENTS; LINIMENT; LIPEMIA; LIPODYSTROPHY; lipoid nephrosis; LIPOLYSIS;LIPOMA; LIPOPROTEINS; LIPOSITOL; LIPOSUCTION; LITHOTRIPSY; LIVER; http://www.mymedadvice.com/html/L_list.htm
Lipoid Nephrosis lipoid nephrosis Nephrotic syndrome. Electron micrograph. Previous Next 1 2 3 4 5 Return to Systemic Pathology Page http://biomed.brown.edu/courses/BI279/Lec09/Lec09-D.htm
072A Lipoid Nephrosis (low) lipoid nephrosis (low), 072A. Glomeruli are normal on light microscopicexamination capillary loops are open with delicate walls http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072A_Full.html
072B Lipoid Nephrosis (high) lipoid nephrosis (high), 072B. Proximal tubular cells show fine vacuolisation( bubbly cytoplasm ) these are lipid droplets, reflecting http://oac.med.jhmi.edu/Pathology/Kidney/NephrSyn/072B_Full.html
Lipoid Nephrosis lipoid nephrosis. TREATMENT steroids; antibiotics; cyclophosphamide; chlorambucil.ICD9-CM 581.3 lipoid nephrosis Date last updated 9/11/01 http://www.5mcc.com/Assets/SUMMARY/0540.html
Extractions: Causes, incidence, and risk factors: Minimal change disease is one cause of nephrotic syndrome . It is named because under a light microscope the glomeruli appear totally normal. Under an electron microscope characteristic changes in the glomeruli can be seen, including the fusion of a portion of the epithelial layer.
ICD-9-CM 580 Foot process disease. lipoid nephrosis. Minimal change http://www.tpmm.com/services/ICD9/1tabular580.html
Extractions: 580 Acute glomerulonephritis 580.4 With lesion of rapidly progressive glomerulonephritis 580.8 With other specified pathological lesion in kidney 580.89 Other 580.9 Acute glomerulonephritis with unspecified pathological lesion in kidney Nephritis specified as acute Nephropathy specified as acute 581 Nephrotic syndrome 581.0 With lesion of proliferative glomerulonephritis
