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Polycystic Kidney: more books (43)

Medifocus Guidebook on: Polycystic Kidney Disease by Medifocus.com Inc., 2010-07-21

The Official Patient's Sourcebook on Polycystic Kidney Disease

Polycystic Kidney Disease (Oxford Clinical Nephrology Series)

Autosomal Dominant Polycystic Kidney Desease: Seminar on Autosomal Dominant Polycystic Kidney Disease, Vimercate, June 18, 1994 (Contributions to Nephrology) by Seminar on Autosomal Dominant Polycystic Kidney Disease, A. Sessa, 1995-12

Polycystic Kidney Disease (Contributions to Nephrology) by M. H. Breuning, M. Devoto, 1992-07

ADPKD patients manual: Understanding and living with autosomal dominant polycystic kidney disease by Irene T Duley, 1995

Problems in Diagnosis and Management of Polycystic Kidney Disease: Proceedings of the First International Workshop on Polycystic Kidney Disease

The Cystic Kidney (Developments in Nephrology)

Conquering Kidney Disease - Identifying Potential Problems by Merle Fields, 2010-05-31

Health tips for living with polycystic kidney disease by Arlene B Chapman, 2001

Polycystic kidney disease: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Paul Johnson, 2005

ADVANCES IN THE PATHOGENESIS OF POLYCYSTIC KIDNEY DISEASE by F.; Dobbie, J.W. Carone, 1990

PKD patient's manual: Understanding & living with autosomal dominant polycystic kidney disease by Irene Duley, 1989

Polycystic Kidney Disease Medical Guide by Qontro Medical Guides, 2008-07-09

lists with details

ESynopsis Of Polycystic Kidney Of The Kidney
eSynopsis of polycystic kidney of Kidney From the Electonic Synopsis of Pathology,the University of Connecticut School of Medicine, Department of Pathology.
http://esynopsis.uchc.edu/S243.htm
Polycystic Kidney Disease
MAIN SEARCH INDEX polycystic kidney disease. polycystic kidney disease (PKD) isone of the most common of all lifethreatening human genetic disorders.
http://www.hendrickhealth.org/healthy/001087.htm

Extractions: Resources Polycystic kidney disease (PKD) is one of the most common of all life-threatening human genetic disorders. It is an incurable genetic disorder characterized by the formation of fluid-filled cysts in the kidneys of affected individuals. These cysts multiply over time. It was originally believed that the cysts eventually caused kidney failure by crowding out the healthy kidney tissue. It is now thought that the kidney damage seen in PKD is actually the result of the body's immune system. The immune system, in its attempts to rid the kidney of the cysts, instead progressively destroys the formerly healthy kidney tissue. A healthy kidney is about the same size as a human fist. PKD cysts, which can be as small as the head of a pin or as large as a grapefruit, can expand the kidneys until each one is bigger than a football and weighs as much as 38lb (17 kg). There are two types of PKD: infantile PKD, which generally shows symptoms prior to birth; and adult onset PKD. Individuals affected with infantile PKD are often stillborn. Among the liveborn individuals affected with infantile PKD, very few of these children survive to the age of two. The adult onset form of PKD is much more common. The time and degree of symptom onset in the adult form of PKD can vary widely, even within a single family with two or more affected individuals. Symptoms of this form of PKD usually start to appear between the ages of 20 and 50. Organ deterioration progresses more slowly in adult onset PKD than it does in the infantile form; but, if left untreated, adult onset PKD also eventually leads to kidney failure.
Nature Publishing Group
23 September 1999. Nature 401, 386 389 (1999); doi10.1038/43916. A polycystickidney-disease gene homologue required for male mating behaviour in C. elegans
http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v401/n6751/full/
The Gene Mutated In Autosomal Recessive Polycystic Kidney Disease Encodes A Larg
3 pp 259 269 The gene mutated in autosomal recessive polycystic kidney diseaseencodes a large, receptor-like protein Christopher J. Ward 1 , Marie C. Hogan
http://www.nature.com/doifinder/10.1038/ng833

Extractions: Autosomal recessive polycystic kidney disease (ARPKD) is characterized by dilation of collecting ducts and by biliary dysgenesis and is an important cause of renal- and liver-related morbidity and mortality. Genetic analysis of a rat with recessive polycystic kidney disease revealed an orthologous relationship between the rat locus and the ARPKD region in humans; a candidate gene was identified. A mutation was characterized in the rat and screening the 66 coding exons of the human ortholog ( ) in 14 probands with ARPKD revealed 6 truncating and 12 missense mutations; 8 of the affected individuals were compound heterozygotes. The transcript, approximately 16 kb long, is expressed in adult and fetal kidney, liver and pancreas and is predicted to encode a large novel protein, fibrocystin, with multiple copies of a domain shared with plexins and transcription factors. Fibrocystin may be a receptor protein that acts in collecting-duct and biliary differentiation.
Polycystic Kidney Disease
polycystic kidney Disease A. Characteristics See outline ChronicRenal Failure Common hereditary disorder, ~0.2% of population
http://www.outlinemed.com/demo/nephrol/11322.htm

Extractions: C. Pathogenesis Autosomal Dominant Disease caused by mutations in at least three genes PKD1 - codes for 4304 amino acid membrane protein called polycystin (chromosome 16) PKD2 - mapped to chromosome 4 Unidentified third locus Cyst formation in kidneys Abnormality in Na+/K+ ATPase Pump Cystic epithelium has pump in apical location Normal renal tubular epithelium has this pump on the basolateral surface Increased programmed cell death (apoptosis) in both dominant and recessive forms [ Mice with homozygous deletions in the proto-oncogene bcl-2 develop PKD [ Other mouse models (pcy and cpk) of the disease are now being studied
GeneReviews: Polycystic Kidney Disease, Autosomal Recessive
Your browser does not support HTML frames so you must view polycystic kidneyDisease, Autosomal Recessive in a slightly less readable form.
http://www.geneclinics.org/profiles/pkd-ar/
Sympathetic Neurons Used To Combat Polycystic Kidney Disease
Press release. Sympathetic neurons used to combat polycystic kidneydisease. Paris, March 29, 2002. Using an atypical research model
http://www.cnrs.fr/cw/en/pres/compress/polykystose.htm

Extractions: Press release Sympathetic neurons used to combat polycystic kidney disease Paris, March 29, 2002 Using an atypical research model, the neuron, Patrick Delmas, of the "Intégration des Informations Sensorielles Laboratory" (CNRS – Marseille), and the research teams of Dr. Jing Zhou and Professor David A. Brown , have achieved significant results with the function of polycystin-1, a human kidney protein whose mutations have been associated with 85% of all cases of polycystic kidney disease. Their work will enable the identification of the metabolic pathways activated by polycystin-1 and provide valuable information about the cellular mechanisms responsible for this disease. These results were published in the March 29 issue of the Journal of Biological Chemistry Autosomal dominant polycystic kidney disease (called ADPKD) is a serious genetic disease with an incidence rate of 1 per 1000 births, which afflicts about 80,000 people in France. Fluid-filled cysts form in the kidneys of ADPKD patients and gradually compress and destroy healthy renal tissue. The disease is one of the primary causes of chronic kidney failure and almost half of all cases require either dialysis or transplantation. The probability of end-stage kidney failure requiring dialysis is 20-25% by the age of 50, 40% by the age of 60, and between 50 and 70% by the age of 70. Treatment to slow the progress of kidney failure in ADPKD patients has thus far been disappointing.
Polycystic Kidney Disease
Research Areas of Study - polycystic kidney DISEASE. FACTS ABOUT PKD PolycysticKidney Disease (PKD) is the most common life threatening genetic disease;
http://www.hwi.buffalo.edu/Research/AreasOfStudy/PolycysticKidney.html
Polycystic Kidney Disease
polycystic kidney Disease. What is it? polycystic kidney disease,or PCKD, is an inherited kidney disorder in which multiple cysts
http://www.hmc.psu.edu/healthinfo/jkl/kidneydisease.htm
Polycystic Kidney Disease - Kidney & Urinary Tract Disorders
polycystic kidney DISEASE. polycystic kidney disease (PKD) is a geneticdisorder characterized by the growth of numerous cysts in the kidneys.
http://www.medicalconsumerguide.com/primary_care/kidney_urinary_tract_disorders/

Extractions: Vision ... Urinary Tract Infection POLYCYSTIC KIDNEY DISEASE Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to failwhich usually happens only after many yearsthe patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD). PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life.
Polycystic Kidney Disease
polycystic kidney disease. Definition. polycystic kidney disease (PKD) is one ofthe most common of all lifethreatening human genetic disorders.
http://www.healthatoz.com/healthatoz/Atoz/ency/polycystic_kidney_disease.html

Extractions: Definition Polycystic kidney disease (PKD) is one of the most common of all life-threatening human genetic disorders. It is an incurable genetic disorder characterized by the formation of fluid-filled cysts in the kidneys of affected individuals. These cysts multiply over time. It was originally believed that the cysts eventually caused kidney failure by crowding out the healthy kidney tissue. It is now thought that the kidney damage seen in PKD is actually the result of the body's immune system. The immune system, in its attempts to rid the kidney of the cysts, instead progressively destroys the formerly healthy kidney tissue. Description A healthy kidney is about the same size as a human fist. PKD cysts, which can be as small as the head of a pin or as large as a grapefruit, can expand the kidneys until each one is bigger than a football and weighs as much as 38lb (17 kg). There are two types of PKD: infantile PKD, which generally shows symptoms prior to birth; and adult onset PKD. Individuals affected with infantile PKD are often stillborn. Among the liveborn individuals affected with infantile PKD, very few of these children survive to the age of two. The adult onset form of PKD is much more common. The time and degree of symptom onset in the adult form of PKD can vary widely, even within a single family with two or more affected individuals. Symptoms of this form of PKD usually start to appear between the ages of 20 and 50. Organ deterioration progresses more slowly in adult onset PKD than it does in the infantile form; but, if left untreated, adult onset PKD also eventually leads to kidney failure.
Polycystic Kidney Disease Prognosis - PKD Treatment Options
polycystic kidney disease (PKD). guide includes information PolycysticKidney Disease, NK012. Medifocus Guide Polycystic
http://www.medifocus.com/zNK012.asp?a=a
POLYCYSTIC KIDNEY DISEASE
polycystic kidney DISEASE.
http://www.netmedicine.com/xray/ctscan/cta22.htm

Extractions: POLYCYSTIC KIDNEY DISEASE View image The axial CT scan done with intravenous contrast demonstrates the presence of bilaterally enlarged kidneys (asterisks) a solitary cyst of the polycystic kidneys is marked with the arrow heads. The left kidney demonstrates the presence of a calcified cyst wall as the result of a previous infection or hemorrhage. The presence of a fluid/fluid level within a cyst may indicate either hemorrhage or infection. NetMedicine Home Page CT Scan Library Downloading and using one of these free programs as a helper application will significantly improve JPEG image quality
Frequency And Impact Of Autosomal Dominant Polycystic Kidney Disease In Seychell
back to original article. Frequency and impact of autosomal dominantpolycystic kidney disease in Seychelles (Indian Ocean). Claude
http://www.seychelles.net/smdj/97issue/orig3.htm

Extractions: about the smdj 1997 issue : Past-issues : classified ads : feedback : index-page back to original article Frequency and impact of autosomal dominant polycystic kidney disease in Seychelles (Indian Ocean) Claude Yersin, MD, Senior Registrar (1); Pascal Bovet, MD, MPH Consultant Epidemiologist (2), Senior Registrar (3); Jean-Pierre Wauters, MD, Professor (4); Daniel F. Schorderet, MD, PhD, Associate Professor (5); Graziano Pescia, MD, Professor (5); Fred Paccaud, MD, Professor (3) (1) Department of Internal Medicine, Victoria Hospital, Ministry of Health, Seychelles (2) Unit for Prevention and Control of Cardiovascular Disease, Ministry of Health, Seychelles (3) Institute of Social and Preventive Medicine, University of Lausanne, Switzerland (4) Division of Nephrology, University Hospital, Lausanne (5) Division of Medical Genetics and Unit of Molecular Genetics, University Hospital, Lausanne This article is reproduced with permission from the journal Abstract Background: As little such data is available in African populations, we investigated the prevalence of autosomal dominant polycystic kidney disease (ADPKD) and the impact of the disease in the Seychelles islands where approximately 65% of the population is of African descent and 30% of Caucasian or mixed descent. Methods: Prevalent cases were identified over a 3-year period by requesting all the doctors in the country (most of them are employed within a national health system) to refer all presumed or confirmed cases and by systematically examining the family members of all confirmed cases. The diagnosis was based on standard criteria including ultrasonographic findings and family history.
MediFocus MedCenter Preview For Polycystic Kidney Disease (PKD)
polycystic kidney Disease (NK012). The Medifocus Guide on polycystic kidney Diseaseprovides answers to the following important questions and medical issues
http://www.slmseniors.com/medguides/nk012.htm

Extractions: MediFocus MedCenter Polycystic Kidney Disease Polycystic Kidney Disease (PKD) is a hereditary disorder that causes fluid-filled cysts to form in the nephrons of the kidneys. These cysts can grow so large and so numerous that they crowd out the normal kidney tissue, rendering the kidneys unable to function normally. Damage to the kidneys is caused by structural deformities caused by the enlarging cysts as well as by elevations in blood pressure (hypertension). Cysts can also form in other organs such as the liver. PKD affects approximately 600,000 persons in the United States. It is one of the most common hereditary diseases and the fourth leading cause of kidney failure. It seems to affect all races and both genders equally. Persons with autosomal dominant PKD often exhibit no symptoms and the disease can not be diagnosed by routine blood work in its early stages. Therefore, persons may have the disease for years before it is diagnosed. Once cysts have formed, they can be seen with noninvasive ultrasound imaging. There is no cure for PKD. Medications or surgery may be used for pain control, to reduce blood pressure and for the treatment of infection. Dialysis is usually eventually necessary to perform functions (removal of toxins from the blood) that the kidneys are no longer able to do. Kidney transplant may be an option for persons with advanced PKD.
Urology - Polycystic Kidney Disease
polycystic kidney Disease. What is polycystic kidney disease (PKD)? Autosomaldominant PKD is often called the adult polycystic kidney disease.
http://www.viahealth.org/disease/urology/polycyst.htm

Extractions: Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys. PKD cysts can reduce kidney function, leading to kidney failure. PKD can also cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. PKD is the fourth leading cause of kidney failure and affects approximately 500,000 people in the US. According to the National Inst itute of Diabetes and Digestive and Kidney Diseases (NIDDK), about one-half of people with autosomal dominant PKD progress to kidney failure, or end-stage renal disease (ESRD). What are the different types of PKD? There are two primary inherited forms of PKD and one non-inherited form: autosomal dominant PKD (inherited) This is the most common inherited form of polycystic kidney disease, accounting for about 90 percent of all PKD cases. "Autosomal dominant" means that if one parent has the disea se, there is a 50 percent chance that the disease will pass to a child, and that both males and females are equally affected.
Child Health Library - Urology - Polycystic Kidney Disease (PKD)
Information Concerning polycystic kidney Disease (PKD) from the Child Health Libraryof Children's Hopital of Pittsburgh. polycystic kidney Disease (PKD)
http://www.chp.edu/greystone/urology/pkd.php

Extractions: About Parents Providers Library ... Research Select Another Subject Adolescent Medicine Arthritis Burns Cardiovascular Disorders Craniofacial Anomalies Dermatology Eye Care Growth and Development High-Risk Newborn High-Risk Pregnancy Infectious Diseases Medical Genetics Mental Health Neurological Disorders Normal Newborn Oncology Orthopaedics Respiratory Disorders Surgery Terminally Ill, Care of Transplantation Urology About Pittsburgh Directions and Parking Departments and Services Neighborhood Locations ... Online Resources Polycystic Kidney Disease (PKD) What is polycystic kidney disease (PKD)?
Department Of Nephrology Patient Care - Polycystic Kidney Disease
What is polycystic kidney Disease? polycystic kidney Disease is a geneticallyinherited disease that involves cysts that grow throughout the kidneys.
http://www.clevelandclinic.org/nephrology/patient/pkd.htm

Extractions: Polycystic Kidney Disease is a genetically inherited disease that involves cysts that grow throughout the kidneys. These cysts cause numerous health problems, such as high blood pressure, fatigue, frequent urination, and low back pain. As time goes on, the disease begins to affect other organs, such as the liver, pancreas, heart, and brain. Eventually, the patient may lose kidney function (End Stage Renal Disease). What are Cysts? However, within a family, although the gene that causes ADPKD is the same, the disease will often follow a different pattern of progression in each person. Thus, it is difficult to predict what one family member will face based on what happened in older generations. Additionally, there is a 10% rate of spontaneous mutation for ADPKD. This means that 10% of the people with the disease did not acquire it from a parent, but had a gene mutate that caused the disease. This newly affected person can pass the ADPKD gene on to their children. ARPKD, the rarer form of polycystic kidney disease, is inherited from
Acute Pyelonephritis Of The Kidney
polycystic kidney of the Kidney From the Virtual Pathology Museum, Department ofPathology, University of Connecticut Health Center. polycystic kidney, Kidney.
http://155.37.5.42/Code/641.htm

Extractions: Acute pyelonephritis, Kidney Acute Pyelonephritis Secondary to Obstruction This is a posterior view of kidneys. The specimen includes metastatic colon carcinoma (T) involving the hilar and proximal peri-ureteral soft tissues on the right. Although not demonstated by this photograph, the tumor growth in this region has led to secondary hydronephrosis and pyelonephritis of the right kidney. Image Contrib. by: UCHC Description by: H. Yamase, M.D. ( 294-6024) More Information
Polycystic Kidney Disease
polycystic kidney disease. Definition Alternative Names Cysts kidneys; Kidney- polycystic; Autosomal dominant polycystic kidney disease; ADPKD.
http://www.pennhealth.com/ency/article/000502.htm

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