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Primary Immune Disorders: more detail

EATING DISORDERS IN PRIMARY CARE A guide to identification and treatment Screening for eating disorders should be a routine part of medical care for children, ... and young adults. (Postgraduate Medicine) by MD Douglas G. Kondo, MD Mae S. Sokol, 2010-05-27

Combat Syndrome X, Y and Z (The Metabolic Syndrome) by M.D. Stephen Holt, 2002

What You Need to Know About Polycythemia Vera - It's Your Life, Live It! by Michael Braham, 2010-10-26

lists with details

ClinicalTrials.gov - Linking Patients To Medical Research: Study Details
Purpose This study will try to identify mutations in the genes responsible for primaryimmunodeficiency disorders (inherited diseases of the immune system) and
http://www.clinicaltrials.gov/ct/gui/show/NCT00006319?order=14
P1
Prescription Drug Assistance Programs. primary Biliary Cirrhosis. primaryImmune disorders. Prion Diseases. Probability and Statistics. Progeria.
http://www.ability.org.uk/p1.html
IPOPI - International Patient Organisation For Primary Immunodeficiencies
Some disorders such as Selective IgA Deficiency can be quite Untreated primary immunedeficiencies are characterized by frequent lifethreatening infections
http://www.ipopi.org/pidinfo/

Extractions: The World Health Organization recognizes approximately 70 primary immune deficiencies including X-Linked Agammaglobulinemia (Bruton's Disease), Common Variable Immune Deficiency (also called Hypogammaglobulinemia), Selective IgA Deficiency, and Severe Combined Immune Deficiency (boy-in-the-bubble disease). Some disorders such as Selective IgA Deficiency can be quite common, occurring as often as 1/500 to 1/1000 individuals. Others may be as rare as 1 individual affected per million. Untreated primary immune deficiencies are characterized by frequent life-threatening infections and debilitating illnesses. Because of advances in our medical understanding and treatment of primary immune deficiency diseases, many patients who in the past would not have survived childhood are now able to live nearly normal lives. Most primary immune deficient patients require life long therapies including intravenous gammaglobulin infusion, aggressive antibiotic therapies, or bone marrow transplantation. Five classes of primary immunodeficiency diseases have been identified: T-lymphocyte disorders (such as the DiGeorge anomaly and chronic mucocutaneous candidiasis);
Primary Immunodeficiency
program. NIAID primary immune Deficiency Fact Sheet from the NationalInstitute of Allergy and Infectious Diseases (US). National
http://rarediseases.about.com/cs/primaryimmunodef/
Infusion Network Systems: Physicians
Clinical Warning Signs of primary immune Deficiency 8 Warning Signs Disordersof Host Defense Immunologist's rule of thumb for determining immunodeficiency,
http://www.infusionsystems.net/physicians.html

Extractions: Infusion Network Systems is dedicated to expanding the knowledge base of the medical community to increase awareness of primary immune deficiency. This is accomplished through lectures, grand rounds, consultations, formal and informal meetings, and medical journal submissions. Our Medical Director, Dr. Robert W. Hostoffer , is a leading immunologist and expert in the field of treating primary immune deficiency. Dr. Hostoffer has been a contributing author in various publications and actively involved as PI in numerous studies in the administration of intravenous immune globulin (IVIG).
Support - KIDS Foundation Of NZ - Everybody.co.nz
OUR ORGANISATION Free seminars on primary immune Deficiency DisordersEarly Diagnosis 10 warning signs. NZ, February 2003. Leading
http://www.everybody.co.nz/support/kids.html
The Dangers Of Smallpox
It is believed that about 1 person in 500,000 has this form of primaryimmune deficiency. Other immune disorders are far more common.
http://www.tucsoncitizen.com/living/2_3_03smallpox.html
OUP USA: ToC: Primary Immunodeficiency Diseases
Inherited disorders with Autoimmunity and Defective Lymphocyte Assessment of the ImmuneSystem, Helen M Genetic Aspects of primary Immunodeficiencies, Jennifer M
http://www.oup-usa.org/toc/tc_0195104862.html
NORD - National Organization For Rare Disorders, Inc.
immune Deficiency Foundation 40 West Chesapeake Avenue Patient Organization for PrimaryImmunodeficiencies Web National Organization for Rare disorders, Inc.
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Granulomatous
MediVibe.com - Welcome To Your Everyday Medical Resource
Obstetrics/Gynecology Oncology Ophthalmology Orthopedics Pediatrics Podiatry PrimaryCare Psychiatry HealthPortal Diseases and Conditions immune disorders
http://medivibe.subportal.com/health/Diseases_and_Conditions/Immune_Disorders/
Te Puna Web Directory > NZ > Health > Children And Young People's Health
KIDS Foundation of New Zealand Inc. Offers support to children and adults withprimary immune deficiencies, immune defects and related blood disorders.
http://webdirectory.natlib.govt.nz/dir/en/nz/health/children-and-young-peoples-h
KIDS Foundation - Medical Advisory Panel
Dr Ameratunga has a special interest in primary immune deficiencydisorders. Dr Ameratunga has received a PhD for genetic studies
http://www.pidsnz.co.nz/panel/panel.htm

Extractions: Medical Advisory Panel Operating as a sub-committee of the KIDS Foundation Board, the Medical Advisory Panel is comprised of eight medical professionals specialising in immunology-related illnesses. Two of the Panelists, Dr Rohan Ameratunga and Dr Jan Sinclair will also strengthen the link with the Foundation by becoming fully-fledged Board directors with voting rights. Dr Ameratunga will cover adult patient issues while Dr Sinclair will advocate for child patient issues. The Panel will provide the Foundation with medical advice, review scientific advances, prepare written articles for 'In Touch' magazine and assist in providing talks or lectures about Primary Immune Deficiency and related conditions. Panelists will also endorse Foundation activities as appropriate and update the Board on any medical service issues and concerns. KIDS Foundation general manager, Janet Simons, says the confirmation of the Medical Advisory Panel signals a new and exciting era for the Foundation. "We see the Panel as the key to building a stronger Foundation team dedicated to achieving more for the immunology service providers as well as PID patients around New Zealand. Having leading medical specialists working closely with the Foundation also enhances our reputation and credibility - an essential cornerstone if we are to raise awareness about PID".
Primary Immunodeficiency
primary immunodeficiencies are complex diseases them is according to the part of theimmune system that In some disorders, the B cells make almost no antibodies
http://156.40.88.3/publications/pubs/primaryimmunobooklet.htm

Extractions: I N T R O D U C T I O N M There are over 70 different types of PIs. Each type has somewhat different symptoms, depending on which parts of the immune defense system are deficient. Some deficiencies are deadly, while some are mild. But they all have one thing in common: they may open the door to multiple infections. In the more severe forms of PI, germs which cause only mild infections in people with healthy immune systems may cause severe or life-threatening infections. Although infections are the hallmark of PIs, they are not always the only health problem, or even the main one. Some PIs are associated with other immune system disorders, such as anemia, arthritis, or autoimmune diseases. Other PIs involve more than the immune system; some, for instance, are associated with symptoms involving the heart, digestive tract, or the nervous system. Some PIs retard growth and increase the risk of cancer. Today, thanks to rapid advances in medicine, many PI diseases can be successfully treated or even cured. With proper treatment, most people with PIs are not only surviving once-deadly diseases, they are usually able to lead normal lives. Children usually can go to school, mix with playmates, and take part in sports. Most adults with PI are leading productive lives in their communities.
Immunopharmacology Page 5
primary and secondary serum antibody responses. induces tolerance for marrow/immunecell grafting Efficacious for managing Autoimmune disorders systemic lupus
http://www.pharmacology2000.com/Hemo/Immunosupression/immuno5.htm

Extractions: Immunosuppressive Cytotoxic Drugs return to main menu Primary use azathioprine: immunosuppression prototype: cytotoxic immunosuppressive drugs return to main menu urinary excretion small amounts of mercaptopurine and unchanged drug also renally excreted return to main menu Mechanism of Immunosuppression Action:azathioprine interference with nucleic acid metabolism
SRBI.COM - Market Research Projects - Primary Immune Deficiency Diseases In Amer
DISEASES IN AMERICA The First National Survey of Patients and Specialists Primaryimmune deficiency diseases represent a class of disorders in which there is
http://www.srbi.com/immune_dificiency.html

Extractions: Primary immune deficiency diseases represent a class of disorders in which there is an intrinsic defect in the human immune system (as distinct from immune disorder that are secondary to infection, chemotherapy, or some other external agent). In some cases, the body fails to produce any or enough antibodies to fight infection. In other cases, the cellular defenses against infection fail to work properly. The first medical recognition of primary immune deficiency diseases was only fifty years ago. Today, the World Health Organization recognizes more than 80 different primary immune deficiency diseases. Although primary immune deficiency diseases are often described as rare disorders, the true population prevalence of these diseases, either individually or collectively, is not well established. The major health surveys conducted by the U.S. government, the National Health Interview Survey and the National Health and Nutrition Examination Survey, do not collect information on primary immune deficiency diseases. No national population survey has ever been undertaken in the United States to estimate the prevalence or the population characteristics of the disease. Hence, although the diseases are clinically described in the medical literature, there is no comprehensive portrait available of the patient with primary immune deficiency diseases.
NIH Study Category Listing (7): Immunology/Infectious Diseases
Inhibitor Conta. Evaluation of Antibody Production in primary ImmuneDisorders. Cryptococcosis in Previously Normal Adults. Treatment
http://www.centerwatch.com/patient/nih/nihcat7.html

Extractions: About the NIH Clinical Center NIH Clinical Trials Search Page Return to NIH Listings Menu Non-NIH Trial Listings ... Additional resources in this illness area Below is a listing of government-funded clinical trials in Immunology/Infectious Diseases, being conducted by the various National Institutes of Health at the Warren Grant Magnuson Clinical Center in Bethesda, MD. Click on a study summary to view the study description and contact information directly from the NIH's web site. Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population Prospective Evaluation of the Significance of Anti-HIV Antibody in Asymptomatic Blood Donors A Phase II Study of Liposomal Doxorubicin and Interleukin-12 in AIDS-Associated Kaposi's Sarcoma Followed by Chronic Administration of Interleukin-12 Immunologic and Virologic Studies of Intermittent Versus Continuous HAART in the Treatment of HIV Disease ... A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Chronic Lyme Infection and Selected Control Populations Last updated: March 28, 2003 at 2:41:17 PM
Clinical Study: 01-HG-0226, Evaluation Of Antibody Production In Primary Immune
Clinical Study Summary Sheet for 01HG-0226
http://clinicalstudies.info.nih.gov/detail/A_2001-HG-0226.html

Extractions: Protocol Number: 01-HG-0226 Evaluation of Antibody Production in Primary Immune Disorders 01-HG-0226 This study will evaluate immune function in people with a known or suspected immune disorder. It will determine participants' immune response to vaccines by measuring blood antibody levels after vaccination. Patients enrolled in a NIH protocol involving immune reconstitution (bone marrow transplantation or gene therapy) for a known or suspected primary immune disorder may be eligible for this study. Participants may be asked to have more than one vaccine, based on their age, use of IVIG, past immunization history and underlying immune problem. The possible vaccinations include: The diphtheria, tetanus, pneumococcus and rabies vaccines are approved by the Food and Drug Administration (FDA) and used routinely to protect against disease. Bacteriophage PhiX174 is approved for research purposes to test immune status. Study participants will have a blood sample drawn before vaccination. The number of additional samples collected will vary according to the vaccines administered-8 for bacteriophage PhiX174; 1 for rabies; 1 for tetanus; and 1 to 2 for the pneumococcal vaccines. Each sample will be up to 5 teaspoonfuls. Participation in the study may last up to a year, depending on the blood sampling scheduling Referral Letter Required: Yes

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