Treatment Of Retinitis Pigmentosa With Vitamin A Treatment of retinitis pigmentosa with Vitamin A Eliot L. Berson, MD BermanGundLaboratory for the Study of Retinal Degenerations, Harvard Medical School http://www.djo.harvard.edu/meei/OA/RPB/RPB.html
Extractions: Eliot L. Berson, M.D., Berman-Gund Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114. Archives of Ophthalmology We found that mean annual rates of decline of remaining ERG amplitude were slowest for the group taking 15,000 IU per day of vitamin A and fastest for the group taking 400 IU per day of vitamin E. These rates were observed among all randomized patients as well as among a subgroup of 354 patients with slightly higher initial ERG amplitudes who could be followed more reliably and whom we designated as "the higher amplitude cohort." Mean annual rates of decline of remaining 30 Hz ERG amplitude among this cohort were as follows: Group A, 8.3%; Group Trace, 10%; Group A+E, 8.8%; and Group E, 11.8%. Rates of decline for visual field area showed similar trends, although the differences were not statistically significant. No significant differences were observed among groups with respect to rates of decline of visual acuity. These results are summarized in Table 1.
Extractions: Eye Focus Annual Report 2001 Understanding your eye condition The "Understanding" series of leaflets is designed to help you, your friends and family understand a little bit more about your eye condition. Each leaflet gives an introduction to the condition, how it can affect you, the main treatment available and how to make the most of your sight. There are details of who to contact for more information at the foot of the page. Retinitis pigmentosa (RP) is the name given to a group of hereditary eye disorders. These disorders affect the retina, which is the light-sensitive tissue lining the back of the eye, in which the first stages of seeing take place. In RP, sight loss is gradual and progressive. It is unusual for people with RP to become totally blind as most retain some useful vision well into old age. The retina in your eye serves a similar purpose to a film inside a camera. Light is focused by a lens at the front of the camera onto a light-sensitive film at the back, to form a picture. In a similar way, light entering your eye is focused onto a light-sensitive tissue which lines the inside of the eye at the back. This tissue is the retina.
Living With Retinitis Pigmentosa Help for those coping with vision loss from retinitis pigmentosa and other retinaldiseases. Features articles and books by Dorothy Stiefel, the. http://www.homebiz101.com/haven/
Extractions: Texas Association of Retinitis Pigmentosa Contact Dorothy I have dedicated this website as a "Lost and Found" haven: a place where people newly diagnosed with RP can come and browse, ask questions and order publications about how I learned to cope with impending blindness. You will discover that you are not alone! I vowed that no one should feel alone and isolated from others when they learn that they have RP or other retinal diseases. In order to locate others like myself, I founded the Texas Association of Retinitis Pigmentosa. This has earned me the title of "The RP Lady." And I certainly had a lifelong quest! For over 20 years now, people have been visiting by phone, in person, and now on the web. Go To Top Relax and enjoy the Haven!
RETINITIS PIGMENTOSA retinitis pigmentosa retinitis pigmentosa or RP is a group of geneticallydetermined,progressive degenerations of the rods and cones of the retina. http://www.medhelp.org/lib/retinit.htm
Extractions: RETINITIS PIGMENTOSA James D. Reynolds, M.D., Univ. of Arkansas School of Medicine Retinitis pigmentosa or RP is a group of geneticallydetermined, progressive degenerations of the rods and cones of the retina. The term retinitis pigmentosa was coined in 1857 by Donders, and like many older terms, it is a misnomer. Despite the "itis," there is no inflammatory or infectious component to this group of diseases. RP classically occurs as an isolated, hereditary condition, but it can be associated with a variety of other diseases. Physiology The retina is the actual sense organ of the eye. The rest of the eye provides support, nourishment, and focusing power. The retina contains several layers of cells, but the group of cells that initially responds to light are the rods and cones. These extremely specialized and sensitive cells transform light energy into electrical energy which is processed in the retina and transmitted to the brain via he optic nerve. Compared to the cones, the rods are a more sensitive, less discriminating cell population. They function best in the dark or near dark. The cones are less sensitive, but more discriminating. They function in well-lighted conditions and are the cells which provide us with our optimal 20/20 vision. The cones are also the cells responsible for the perception of color. These two groups of cells form a complimentary dual system. Classification Generalized rod-cone degenerations are classified in a variable way and few authors agree completely on the classifications. The following grouping is somewhat simplified:
Retinitis Pigmentosa (RP) - @med1 Translate this page Was ist retinitis pigmentosa? Unsere Nutzungs- bedingungen. Was ist RetinitisPigmentosa? - eine Einführung. Grauer Star und retinitis pigmentosa. http://www.med1.de/Laien/Krankheiten/Augen/Retinitis.Pigmentosa/
LaserSurgeryForEyes.com Site Map. Home. retinitis pigmentosa. retinitis pigmentosa is a hereditary diseasecharacterized by a gradually shrinking field of vision leading to blindness. http://www.lasersurgeryforeyes.com/retinitispigmentosa.html
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Retinitis Pigmentosa Translate this page retinitis pigmentosa. Nähere Informationen. Nähere Informationenzu retinitis pigmentosa erhalten Sie bei Pro Retina Deutschland. http://www.reineckerreha.de/augenkrankheiten/rp.htm
Extractions: Blickfeld eines RP-Betroffenen Beim klassischen Verlauf der RP beginnt sich das Geschichtsfeld von den Außenzonen her einzuengen, bis nur ein kleiner Sehrest im Zentrum übrig bleibt, der so genannte "Tunnelblick" oder das Röhrengesichtsfeld. Bei dieser typischen Form der RP ist die Orientierung im Raum erheblich erschwert, während das Sehen im Zentrum noch funktioniert.
Clinical Studies - Randomized Trial For Retinitis Pigmentosa Randomized Trial for retinitis pigmentosa. To determine whether a nutritional supplementin addition to vitamin A will slow the course of retinitis pigmentosa. http://www.nei.nih.gov/neitrials/static/study12.htm
Extractions: CS Home Search for a Study Participate in a Study Refer a Patient to a Study ... NEI Home Purpose Background Description Patient Eligibility ... NEI Representative To determine whether a nutritional supplement in addition to vitamin A will slow the course of retinitis pigmentosa. Retinitis pigmentosa (RP) is a group of inherited retinal degenerations with a worldwide prevalence of approximately 1 in 4,000. Patients typically report night blindness and difficulty with midperipheral visual field in adolescence. As the condition progresses, they lose far peripheral visual field. Most patients have reductions in central vision by age 50 to 80 years. Based on electroretinograms (ERGs), the course of the disease can be slowed on average among adults on 15,000 IU/day of vitamin A palmitate. While conducting the trial on the effects of vitamin A on RP, it became apparent that another substance in the diet could be affecting the course of the disease. This prompted the present randomized, controlled trial. This study is a randomized, controlled, double-masked trial with a planned duration of 5 years. Patients with the common forms of RP are assigned to either a test or a control group. All receive 15,000 IU/day of vitamin A palmitate in addition to the capsules under study. Participants will not know the contents of the supplement or the group to which they have been assigned until the end of the trial. The main outcome measurement is the total point score on the Humphrey Field Analyzer (HFA). In addition, computer-averaged 30-Hz cone ERG amplitudes and visual acuity are measured annually.
Retinitis Pigmentosa Patient Education. retinitis pigmentosa. retinitis pigmentosa and its group of relateddiseases can run in families and cause slow, progressive loss of vision. http://bri.wustl.edu/edu_retinitis.html
Extractions: Patient Education RETINITIS PIGMENTOSA Retinitis pigmentosa and its group of related diseases can run in families and cause slow, progressive loss of vision. In retinitis pigmentosa, there is slow destruction of certain cells in the retina. What are the symptoms of retinitis pigmentosa? Night blindness and loss of peripheral vision are the most common symptoms. Patients with retinitis pigmentosa have difficulty adjusting to darkness, and this is especially evident when people go to a movie theater. How is the diagnosis of retinitis pigmentosa made? The diagnosis is made by examination of the retina along with an electroretinogram. An electroretinogram measures the electrical activity of the retina. It is similar to an electrocardiogram which measures the electrical activity of the heart. Examination of family members is also important since variability within the disease exists. Genetic counseling would be important for family planning and a person's occupation. What is the treatment for retinitis pigmentosa?
Retinis Pigmentosa retinitis pigmentosa retinitis pigmentosa (RP) refers to a group ofdiseases that cause slow, but progressive loss of vision. The http://www.betacom.com/betacom/retin_pig.html
Extractions: Retinitis Pigmentosa Retinitis pigmentosa (RP) refers to a group of diseases that cause slow, but progressive loss of vision. The retina is the tissue which lines the inside of the eye and sends visual images to the brain. In RP, some of the light sensing cells in the retina are gradually destroyed. Although RP is commonly considered to be a hereditary condition, it is important to note that approximately fifty percent of RP cases are sporadic.
Retinitis Pigmentosa oogheelkunde. retinitis pigmentosa. Hoe vaak komt het voor ? Geschat wordt,dat ongeveer 14000 mensen retinitis pigmentosa (RP) hebben. http://www.ziekenhuis.nl/ziektebeelden/79.html
Extractions: Retinitis pigmentosa (ook wel T.R.D., tapetoretinale dystrofie, genoemd) is eigenlijk niet één ziekte maar een verzamelnaam voor een groep ziekten die gekenmerkt worden door slecht zien in het donker (nachtblindheid) en zeer geleidelijke beperking van het gezichtsveld, die uiteindelijk leidt tot kokerzien. De ernst en het beloop kunnen heel erg wisselen: soms zijn de symptomen al op kinderleeftijd duidelijk; soms wordt de ziekte pas op middelbare leeftijd vastgesteld. Wij gaan ervan uit dat de aanleg om de ziekte te krijgen, wel in alle gevallen erfelijk bepaald is. Het gaat hierbij om verschillende vormen van erfelijkheid, waarbij de kans om de aandoening over te dragen op eventuele kinderen varieert van zeer gering (minder dan 1%) tot vrij aanzienlijk (maximaal 50%). Indien u een erfelijkheidsonderzoek wilt, kunt u dat overleggen met uw oogarts of met uw huisarts. Geschat wordt, dat ongeveer 1:4000 mensen retinitis pigmentosa (RP) hebben. Dat betekent, dat er tegen de 4000 mensen met deze aandoening in Nederland moeten zijn. Voor oogartsen is de ziekte goed bekend, maar voor huisartsen is dat helaas niet zo, omdat de kans dat zij ermee te maken krijgen veel kleiner is. Omdat de aanleg voor de ziekte erfelijk is, zullen soms meerdere familieleden RP hebben, zodat de ziekte en het beloop al uit ervaring bekend zijn. Toch kunnen er grote verschillen zijn in het beloop van de ziekte, zelfs binnen één familie! Bovendien is het zo, dat bij ongeveer de helft van de RP-patiënten geen andere familieleden met de aandoening bekend zijn.
Blindness And Visual Impairment Centre: Retinitis Pigmentosa retinitis pigmentosa. What is retinitis pigmentosa? Causes and Symptoms.The cause of retinitis pigmentosa has not been clearly identified. http://www.cnib.ca/eng/eye_con/cospubs/rtnspgmt.htm
Extractions: Research What is Retinitis Pigmentosa? Retinitis pigmentosa (RP) refers to a group of diseases which tend to run in families and cause slow, but progressive loss of vision. The retina is the tissue which lines the inside of the eye and sends visual images to the brain. In RP, there is gradual destruction of some of the light sensing cells in the retina. Causes and Symptoms The cause of retinitis pigmentosa has not been clearly identified. About fifty percent of RP cases are sporadic with the remaining cases being hereditary. Learning more about the history of people with RP may help predict how the disease will progress for the affected person, although variations can exist even from person to person within a family. The first symptoms usually start during young adulthood, although it may be seen first at any age. The two most common symptoms are night blindness (where adjusting to the dark happens very slowly) and the loss of side vision. Loss of side or peripheral vision makes mobility very difficult. Once this occurs, a person is left with only central vision (as if looking down a tunnel). Treatment While developments are on the horizonparticularly in the area of genetic researchas yet, there is no cure for retinitis pigmentosa. The retina is attached to the optic nerve and transplants are not yet an option.
Retinitis Pigmentosa retinitis pigmentosa RP. The term Retinitis to surgery. The Geneticsof retinitis pigmentosa. Autosomal Recessive Inheritance This http://www.macular-degeneration.org/Conditions/RP/rp.html
Extractions: Treatments: Sunglasses ... Low Vision Aids Contacts: MDN Bulletin Board Who's Who The EyeCare Foundation The Bookstore ... Retinitis Pigmentosa - RP The term Retinitis Pigmentosa represents a group of retinal diseases characterized by progressive degeneration of the peripheral retina. The term " retin " " itis " is descriptive. It means there are signs of retin al " itis " or inflammation. Similarly, the term " pigment osa" relates to the spicular pigment ation which forms within affected retina. Though there is inflammation associated with RP, it is not thought to be contagious. RP typically affects the peripheral retina first resulting in loss of peripheral vision. To get an idea what this is like for an RP patient, you might try looking through the hole in a donut. You will see that RP causes tunnel vision. This means that while an RP patient's central vision can be excellent while their ability to simultaneously look to the sides, up or down is markedly impaired. Sometimes RP is associated with hearing loss and this is called
Extractions: Informacje o dzia³alno¶ci Polskiego Stowarzyszenia RP Retinitis Pigmentosa (czêsto u¿ywany jest skrót RP), czyli zwyrodnienie barwnikowe siatkówki, jest chorob± dziedziczn±, która w skrajnych przypadkach mo¿e prowadziæ do utraty wzroku. Jest to jedna z klasycznych chorób na tle genetycznym.
Retinitis Pigmentosa Eye. retinitis pigmentosa. retinitis pigmentosa is a progressive lossof vision. retinitis pigmentosa What is retinitis pigmentosa? http://jhhs.client.web-health.com/web-health/topics/GeneralHealth/generalhealths
Blindness Resource Center: Eye Diseases And Conditions Top of Listing retinitis pigmentosa retinitis pigmentosa (RP) progressive lossof peripheral vision, usually beginning with night blindness in young adulthood; http://www.nyise.org/eye.htm
Breakthrough For Retinitis Pigmentosa Breakthrough for retinitis pigmentosa Isolating the genes. Retinitispigmentosa, a degenerative disease of the retina, is the leading http://www.scienceinafrica.co.za/2001/july/pigment.htm
Extractions: Isolating the genes Retinitis pigmentosa, a degenerative disease of the retina, is the leading heritable cause of blindness today. The condition is caused by mutations in genes responsible for a number of different retinal components. These genes and disease-causing mutations can be inherited. Modern genetic technologies allow for the location of these genes and mutations. Once found their effects can be studied, and the foundation laid down for the potential development of gene-based therapies. A research team at the University of Cape Town, headed by Human Genetics professors Raj Ramesar, who also directs the Medical Research Council's Human Genetics Reseach Unit, and Jacquie Greenberg, working with Dr Chris Inglehearn in Leeds in the UK, have found the genetic defect which causes a form of retinitis pigmentosa. This form of the condition was prevalent in a very large family in South Africa, and with the co-operation of key members of the kindred, the UCT and UK researchers were able to track down the mutation responsible for their condition. The gene responsible was found on chromosome 17.
Retinitis Pigmentosa (Night) Vision Simulator The retinitis pigmentosa Simulator is designed to help patients and their caregiversbetter understand the possible progression of vision loss caused by this http://my-vision-simulator.com/retinitis_pigmentosa_night/
Extractions: What is retinitis pigmentosa? Retinitis pigmentosa is actually a group of diseases that cause a slow progressive vision loss. Approximately 200,000 Americans have some form of retinitis pigmentosa. In most cases, retinitis pigmentosa is inherited, although it may skip generations. People with retinitis pigmentosa may also develop other treatable eye diseases, such as glaucoma or cataracts. What are the symptoms of retinitis pigmentosa? What causes retinitis pigmentosa? People with retinitis pigmentosa gradually lose the light-sensitive cells at the back of the eye. These cells of the retina are called rods and cones. As the cells die, vision decreases. How is retinitis pigmentosa treated? At present there is no cure for retinitis pigmentosa. The progress of the disease can sometimes be slowed to preserve vision. Current research focuses on the genetic factors. Understanding how retinitis pigmentosa is passed along could help in finding a way to treat or prevent it. Additional Resources Ophthalmology Resource Center
Eye Conditions > Retinitis Pigmentosa -- EyeMDLink.com Last Updated 9/25/2001. retinitis pigmentosa. The dark, red bone spicule pigment spots on the right side of the photo are a classic sign of RP. http://www.eyemdlink.com/Condition.asp?ConditionID=391
