Publications: Michael Dean, Ph.D A liverspecific ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamilymaps to human chromosome 2p21 in the region of the sitosterolemia locus http://home.ncifcrf.gov/ccr/lgd/about/staff/deanm_pn.asp
Extractions: Annilo, T., Shulenin, S., Chen, Z.Q., Arnould, I., Prades, C., Lemoine, C., Maintoux-Larois, C., Devaud, C., Dean, M. , Denèfle, P., and Rosier, M.: Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34. Cytogenet. Genome. Res. (in press, 2003).
Riesgo De Hipoglicemía En Diabéticos Translate this page de colesterol en el tracto digestivo. sitosterolemia y transportadoresdependientes de ATP. Por razones hasta hace poco desconocidas http://www.galenored.com/galeno/galeno/avances/colesterol.htm
Extractions: En años recientes, diferentes grupos de investigadores han hecho importantes descubrimientos relacionados con el transporte intracelular de colesterol. Tales avances han permitido comprender mejor el metabolismo de los lípidos y abren enormes posibilidades para el desarrollo de medicamentos, con el fin de controlar condiciones clínicas adversas como dislipidemias y aterosclerosis. En este contexto, resultan de enorme importancia dos estudios recientes que revelan aspectos desconocidos hasta el momento sobre la absorción y transporte de colesterol en el tracto digestivo. Sitosterolemia y transportadores dependientes de ATP Por razones hasta hace poco desconocidas, sólo 5% de los homólogos vegetales del colesterol (sitosterol, estigmasterol, campestrol), presentes en la dieta, son absorbidos en el intestino. En una rara enfermedad, denominada sitosterolemia, hay un paso masivo de tales moléculas a la circulación sanguínea. Los pacientes afectados desarrollan hipercolesterolemia, aterosclerosis y enfermedad coronaria a temprana edad. Con el fin de identificar el defecto subyacente, investigadores de
DiabetoValens.com - The Diabetes Guide The FDA also approved ZETIA for use in two rare genetic disorders homozygousfamilial hypercholesterolemia and homozygous sitosterolemia. http://my.diabetovalens.com/diab_update/latestnews.asp?newsid=363
Rabbit Polyclonal To ABCG8 The mutated form of this transporter can lead to sterol accumulation and atherosclerosisor sitosterolemia, a rare autosomal recessive disorder, characterized http://www.novus-biologicals.com/data_sheet.php/4389/N
Extractions: ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.
Extractions: The National Human Genome Research Institute (NHGRI) leads the National Institutes of Health's effort in the Human Genome Project. The NHGRI's Division of Extramural Research (DER) funds Human Genome Project research in laboratories throughout the country. Research on genetic and physical mapping, DNA sequencing, database development, technology development for genome research, and studies of the ethical, legal, and social implications of genetics research are supported by the extramural arm of the NHGRI. NHGRI's Division of Intramural Research (DIR) applies the tools of the Human Genome Project to the study of human genetic diseases, their diagnosis and treatment. Recent Scientific Advances in Tools for Gene Discovery Detailed Maps of Human Chromosomes: Earlier this year, the Human Genome Project passed an important milestone when the human X chromosome was fully mapped with landmarks spaced about 75,000 base pairs apart. This map of a human chromosome was the first to meet or exceed the Human Genome Project goal of markers every 100,000 base pairs. The map will greatly benefit research into X-linked disease genes. In August 1997, a team headed by NHGRI DIR scientists completed a map of human chromosome 7, which contains an estimated 5 percent of the human genome and a total of 170 million base pairs. Scientists are now starting to sequence that chromosome from beginning to end, which will provide important information to study such human genetic diseases as cerebral cavernous malformations (CCM1), Pendred syndrome, Charcot-Marie-Tooth syndrome (CMT2D), and Williams syndrome.
Merck Newsroom Other indications. The FDA also approved ZETIA for use in two rare genetic disordershomozygous familial hypercholesterolemia and homozygous sitosterolemia. http://www.merck.com/newsroom/press_releases/102502.html
Extractions: Full Prescribing Information Patient Product Information FDA Approves ZETIA TM (ezetimibe) for Cholesterol Reduction First New Class To Treat Cholesterol Since Statins Introduced 15 Years Ago; Studies Show Significant Reductions in LDL Cholesterol When Added to All Statins Tested WHITEHOUSE STATION and KENILWORTH, N.J., Oct. 25, 2002 Following a 10-month review, the FDA has approved ZETIA TM (ezetimibe), the first in a new class of cholesterol-lowering agents that inhibits the intestinal absorption of cholesterol, Merck/Schering-Plough Pharmaceuticals announced today. The once-daily tablet of ZETIA 10 mg was approved for use either by itself or together with statins in patients with high cholesterol to reduce LDL "bad" cholesterol and total cholesterol. Cholesterol-lowering medicines should be used in addition to an appropriate diet when the response to diet and exercise has been inadequate.
EHS: Mosby's Drug Consult - Drug Updates - Ezetimibe 003574 Categories, Drug Classes, Brand Names Cost Of Therapy. CATEGORIES Hypercholesterolemia;Hyperlipidemia; sitosterolemia; Pregnancy; FDA Approved 2002 Oct. http://www.mosbysdrugconsult.com/DrugConsult/003574.html
Extractions: Drug Consult Home Log In Drug Updates Description ... Contact Us CATEGORIES: Hypercholesterolemia; Hyperlipidemia; Sitosterolemia; Pregnancy; FDA Approved 2002 Oct Drug Classes: Antihyperlipidemics Brand Names: Zetia Ezetimibe is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. The chemical name of ezetimibe is 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone. The empirical formula is C H F NO . Its molecular weight is 409.4. Background Clinical studies have demonstrated that elevated levels of total cholesterol (total-C), low density lipoprotein cholesterol (LDL-C) and apolipoprotein B (Apo B), the major protein constituent of LDL, promote human atherosclerosis. In addition, decreased levels of high density lipoprotein cholesterol (HDL-C) are associated with the development of atherosclerosis. Epidemiologic studies have established that cardiovascular morbidity and mortality vary directly with the level of total-C and LDL-C and inversely with the level of HDL-C. Like LDL, cholesterol-enriched triglyceride-rich lipoproteins, including very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), and remnants, can also promote atherosclerosis. The independent effect of raising HDL-C or lowering triglycerides (TG) on the risk of coronary and cardiovascular morbidity and mortality has not been determined.
Sitosterolemia Information Sites Reviewed sitosterolemia sites, by people who know sitosterolemia andwork with sitosterolemia. HEALTHorgs.com. Search The Largest http://www.healthorgs.com/ConditionsandDiseases/NutritionandMetabolismDisorders/
ML_ADD\[XFÇ¡Ãò Homozygous sitosterolemiaZETIA is indicated as adjunctive therapy to dietfor the reduction of elevated sitosterol and campesterol levels in patients http://www.fukumi.co.jp/mm/add/mp_hyperlipemia.htm
GeneCards: List Of Disease Genes ABCG5, ATPbinding cassette, sub-family G (WHITE), member 5 (sterolin1), 2p21, sitosterolemia. ABCG8, ATP-binding cassette, sub-family http://genecards.bcgsc.ca/cgi-bin/listdiseasecards?type=full
Sitosterolemia Websites From Linkspider.org The Best Results for sitosterolemia from the Linkspider Organization.Click here for sitosterolemia listings. Complete Directory http://www.linkspider.org/Health/ConditionsandDiseases/NutritionandMetabolismDis
Extractions: Directory Tree: Top Health Conditions and Diseases Nutrition and Metabolism Disorders ... Cholesterol and Other Fats : Sitosterolemia (3) Add URL Advertise Here! Personalize Amazon ... Sitosterolemia - A press release with a brief explanation of this disease. Sitosterolemia - An article about this uncommon genetic lipid disorder and the gene that is responsible for it. Scientists Closer To Locating Gene That May Explain Cholesterol Absorption - An article about a study of 10 families with sitosterolemia, a rare, recessively inherited disease.
Diseases Solved After Completion Of The June 2001 Analysis R50954, 10.0, 35, 56, 7, sitosterolemia, 5453902 NP_006214, protein (peptidylprolylcis/trans isomerase) NIMA-interacting, 4 (parvulin) Homo sapiens, 0.000912, http://www.bork.embl-heidelberg.de/g2d/table_resolved.html
List Of Tests Cholestanol (Cerebrotendinous xanthomatosis). Sitosterol (sitosterolemia, Phytosterolemia).Free Fatty Acids Total level and qualitative analysis. Desmosterol. http://www.genetics.kennedykrieger.org/TestList.htm
Extractions: If you wish to print all test forms at once please use the following link: All Forms Clinical Mass Spectrometry Section Organic acid gas chromatography/mass spectrometry N-acetyl-l-aspartic acid (Canavan disease) Canavan disease - prenatal diagnosis 3-Methylglutaconic acid ... Mevalonic Acid Peroxisomal Diseases Section Plasma Very Long Chain Fatty Acids: Includes Phytanic Acid (screening test for peroxisomal disorders) Red Blood Cell Plasmalogen Content (screening test for rhizomelic chondrodysplasia punctata) Plasma Total Lipid Fatty Acid Profile: Includes C8 to C26 saturated, monounsaturated, polyunsaturated, trans and branched chain fatty acids Red Blood Cell Total Lipid Fatty Acid Profile: Includes C8 to C26 saturated, monounsaturated, polyunsaturated fatty acids and plasmalogens ...
IX Sitosterolemia Nutrition and Metabolism Disorders, Cholesterol and Other Fats, sitosterolemia, sitosterolemiaT A press release with a brief explanation of this disease. http://ix.joal.net/en/Health/Conditions_and_Diseases/Nutrition_and_Metabolism_Di
Sitosterolemia In Health > Conditions And Diseases > Nutrition And Metabolism Di Similar pages ScheringPlough SP in the News Other indications The FDA also approved ZETIA for use in two rare genetic disordershomozygous familial hypercholesterolemia and homozygous sitosterolemia. http://ilectric.com/browse/web/Health/Conditions_and_Diseases/Nutrition_and_Meta
Extractions: Metasearch Directory News Multi-Search ... Login/Out Choose a Search Metasearch - The Web Metasearch - This Site Metasearch - News Metasearch - Auctions Metasearch - Forums Metasearch - Images Metasearch - Shopping Directory - Within This Category Only Directory - Entire Directory - Adult Directory - Arts Directory - Business Directory - Computers Directory - Games Directory - Health Directory - Home Directory - News Directory - Recreation Directory - Reference Directory - Regional Directory - Science Directory - Shopping Directory - Society Directory - Sports Directory - World Shopping - All products Shopping - Books Shopping - Electronics Shopping - Popular music Shopping - Classical music Shopping - DVD's Shopping - VHS Videos Shopping - In Theaters Shopping - Toys Shopping - Computer Hardware Shopping - Software Shopping - Magazines Shopping - Photo Shopping - Garden / Outdoor Living Shopping - Baby Shopping - Kitchen Lookup - Domain in Whois Lookup - Domain Availability Lookup - HTTP Source Lookup - DNS Record Categories Related Sponsored Sites Sites ... Cholesterol and Other Fats Sitosterolemia
