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testicular cancer article written for family physicians at the website of American Academy of Family Category Health Conditions and Diseases Genitourinary TesticularMay 1, 1999 AFP testicular cancer. SCOTT KINKADE overall. Testicularcancer accounts for only about 1 percent of all cancers in males. It
http://www.aafp.org/afp/990501ap/2539.html

Extractions: Advanced Search A patient information handout on testicular cancer, written by the author of this article, is provided on page 2549. T esticular cancer accounts for only about 1 percent of all cancers in males. It is, however, the most common tumor in males between 15 and 34 years of age. About 7,600 cases were expected in the United States in 1998, or about 4.2 cases per 100,000 males. Incidence rates vary across the globe, with higher rates in Scandinavia and Germany and lower rates in Asia and Africa. The incidence of testicular cancer in the United States has almost doubled since the 1930s and continues to climb, while more effective treatments have led to a decline in mortality (Figure 1 The survival rate in 1963 was 63 percent ; the five-year survival rate now exceeds 95 percent. Testicular Cancer FIGURE 1. Testicular cancer incidence and rates of mortality in the United States, 1973 to 1995. Information from Ries LG, Kosary CL, Hankey BF, Miller BA, Edwards BK, eds. SEER cancer statistics review, 1973-1995. Bethesda, Md.: U.S. Dept of Health and Human Services, Public Health Institute, National Institutes of Health, 1998. Retrieved November 1998 from the World Wide Web:
Orchid Cancer Appeal, The - Testicular Cancer
British charity promotes awareness of prostate and testicular cancer. Watch informative videos and learn how to help the cause.
http://www.orchid-cancer.org.uk/
Testicular Cancer
Concise and general information regarding testicular cancer. Provides a colored sketch of the anatomy.
http://www.uro.com/tcancer.htm

Extractions: Testicular Cancer What is testicular cancer? How is testicular cancer diagnosed? How is testicular cancer treated? What is testicular cancer? Testicular cancer occurs in approximately 1 in 25,000 men per year. It is 4 times less common in Afro-American men compared to Caucasian men. The risk of developing testicular cancer in a mans lifetime is approximately 1 in 500. It occurs most commonly between the ages of 15 and 40 years. It can also occur in infancy and late adulthood (e.g. over 60 years old). Individuals who have had an undescended testicle are at higher risk of developing testicular cancer. How is testicular cancer diagnosed? The best way to diagnose testicular cancer is through self-examinations . The usual initial finding is a painless lump in or on the testis, a hardness or enlargement of the testis. Less commonly there is associated pain and tenderness. If problems do occur and an individual is concerned due to tenderness, bloody discharge or a lump for some symptoms they should see a urologist. The urologist will do a physical examination and possibly order a testicular ultrasound. Non-cancerous masses found around the testicle can be fluid collections or cysts. In addition, dilation of some of the veins in the scrotum (
Testicular Cancer - Urologychannel
testicular cancer is a relatively rare but treatable form of cancer. Although it accounts for only 1 percent of cancers in men, it is the most common cancer in young men.
http://www.urologychannel.com/testicularcancer/index.shtml

Extractions: Overview Testicular cancer develops in the testicles (testes), the male reproductive glands. The testicles are located in the scrotum (membranous pouch below the penis) and are suspended from the body by the spermatic cord. They produce sperm (male reproductive cells) and testosterone. Testicular cancer is treated successfully in more than 95% of cases. Anatomy The testicles are primarily made up of a mass of seminiferous tubules in which sperm develop. The tubules are lined with Sertoli cells, which protect and supply nutrients to developing sperm. Sertoli cells also secrete the hormone inhibin, which is involved in the regulation of sperm production. Leydig cells, located in tissue between the seminiferous tubules, secrete testosterone and androsterone. These hormones stimulate the development of male sex organs, beard growth, muscle mass, and deepening of the voice.
What You Need To Know About Testicular Cancer
CancerHelp UK covers a wide range of topics including cancer prevention, diagnosis, treatment and follow up and has an extensive questions and answers section. revised and updated. Overview. About testicular cancer. Diagnosing testicular cancer. Treating testicular cancer
http://rex.nci.nih.gov/WTNK_PUBS/testicular

Extractions: Testicular Cancer The National Cancer Institute (NCI) has prepared this booklet to help patients and their families better understand and deal with testicular cancer. We also hope it will encourage all readers to learn more about this disease. The information presented hereon the symptoms, diagnosis, and treatment of testicular cancer and on living with the diseaseis intended to add to information from doctors, nurses, and other members of the medical team. Throughout this booklet, words that may be new to readers are printed as italicized hot links . A glossary with definitions of these words and other terms related to testicular cancer can be found in the Medical Terms section. For some words, a "sounds-like" spelling is also given. Research sponsored by NCI and other groups has led to better methods of diagnosing and treating this disease. Most men with testicular cancer can now be cured, and continuing research offers hope that in the future even more people with this disease will be treated successfully. Our knowledge about testicular cancer continues to increase. For up-to-date information, call the NCI-supported Cancer Information Service (CIS) at 1-800-4-CANCER (1-800-422-6237).
CancerHelp UK
Provides news and information about the prevention, treatment and cure of testicular cancer. A UK Category Health Conditions and Diseases Genitourinary Testiculartesticular cancer. This section was originally developed from the CancerBACUPbooklet series. It has since been extensively revised and updated.
http://www.cancerhelp.org.uk/help/default.asp?page=2665
Testicular Cancer: Survival High With Early Treatment
In men aged 15 to 34, testicular cancer ranks as the most common cancer.Category Health Conditions and Diseases Genitourinary TesticularFDA Home Page Table of Contents. testicular cancer Survival High with EarlyTreatment. Only 15 years ago, a diagnosis of testicular cancer was grim news.
http://www.fda.gov/fdac/features/196_test.html

Extractions: Survival High with Early Treatment by John Henkel Glenn Knies wasn't thinking the worst when he felt the abnormality in his groin area 11 years ago. It was probably a hernia, he guessed. He had just finished working out. In the shower, he noticed his right testicle seemed enlarged. "I thought I had strained something," says Knies, an insurance adjuster in Schwenksville, Pa. He was 23 and barely out of college at the time. "I wasn't having any discomfort or symptoms to speak of," he says. "I was strong as ever, and there was nothing else to indicate a problem." He mentioned the condition to his mother, a nurse, who urged him to see a urologist quickly. She suspected something more serious than a hernia was bothering her son. His doctor determined the enlargement was cancer, and he removed Knies' right testicle, the standard first-line treatment for testicular tumors. Later, after tests showed that cancer may have spread to the lymph nodes deep within the abdomen where the testicles drain, doctors also removed the nodes. But the lymph nodes were "clean," free of cancer, Knies says. It was the first sign that he probably was going to be OK, that his doctor likely had gotten all the cancer after removing the testicle. To make sure, a regimen of regular examinations followedmonthly at first, tapering off to annually after five years. Eleven years later, he still has a yearly exam but considers himself a cancer survivor.
Sloan-Kettering - Testicular Cancer
The incidence of testicular cancer is rising in the United States, and it is the most common solid tumor diagnosed in men between the ages of 15 and 35 years.
http://www.mskcc.org/mskcc/html/445.cfm

Extractions: The incidence of testicular cancer is rising in the United States, and it is the most common solid tumor diagnosed in men between the ages of 15 and 35 years. Not too long ago, testicular cancer was considered a difficult and dangerous type of tumor. Advances in treatment mean that most men diagnosed with testicular cancer, especially those diagnosed when the cancer is at an early, treatable stage, can now expect to survive the disease. In this section you can find up-to-date information about testicular cancer, and learn about Memorial Sloan-Kettering's expertise in caring for patients with this disease.
Testicular Cancer, The Cancer Infomation Network
A physician guided site for testicular cancer patients, their families, and caregivers. Provides informat Category Health Conditions and Diseases Genitourinary Testicular Health Topics testicular cancer This short article provides answersto several basic questions about testicular cancer. Cancer
http://www.thecancer.info/testicular/

Extractions: First Steps After Diagnosis of Cancer Top 10 Cancer Sites, Treatment Centers, and Cancer Books for Newly Diagnosed Patients. Cancer Patients: Known Your Rights. Understanding Prognosis and Cancer Statistics - answers the most important question, "What is my prognosis?" Support Groups for Cancer Patients ... Pediatric Cancers Welcome to The Cancer Information Network Redirecting to new URL
Testicular Cancer Self-Exam, CancerLinksUSA.com
Offers background, risk factors, and instructions for performing testicular selfscam.
http://www.ontumor.com/testicular/selfexam.htm

Extractions: We Link, You Find! Top Feature Top 10 Links Associations Cancer Centers Research Related ... Glossary For Professionals Main Page Journal Club Meetings Tools About Us Book Store Contact Us Sign Guest Book Site Map Other Links Newsgroups TESTICULAR SELF-EXAMINATION (TSE) Testicular cancer is the most common type of cancer in men between 15 and 35 years of age. Although it accounts for only about 1 percent of all cancers in men, it is the number one cancer killer among men in their 20's and 30's. The disease is highly curable if it is diagnosed in early stage. Men can greatly increase their chances of early diagnosis by performing a simple procedure called testicular self-examination (TSE). Risk Factors: The disease develops more frequently in Whites than in Blacks. Men with a past history of undescended testicles at birth are at higher risk. Self-exam is especially important for these individuals.
TC-Cancer - Testicular Cancer Information & Support, Testical Cancer, Testicle T
Provides information and support services for testicular cancer, addressing such topics as signs, Category Health Conditions and Diseases Genitourinary TesticularThe testicular cancer Information, Resource and Support Center. Developedto help patients with testicular cancer and their family members.
http://www.tc-cancer.com/
Index
testicular cancer patient shares his experiences as he battles the disease and receives chemotherapy treatments.
http://www.michaelmerrill.com

Extractions: Send Michael an E-mail Your Source for News and Updates About Michael During His Treatment and Recovery O n September 6, 2001, Michael was diagnosed with Nonseminoma Testicular Cancer . Six short days later, after an inguinal orchiectomy , he was on the road to recovery. It certainly hasn't been easy. It seems that just when every effort and determination should be aimed at simply getting well, he has been forced to deal with all the issues related to learning about cancer and managing his treatment. These issues include learning about the different types of cancers, finding good doctors, choosing among the different treatment options, understanding and interpreting test results (sometimes better than the doctors), going to doctors' appointments, dealing with insurance companies, going on short-term disability, and thinking about and coping with the reality of infertility. Needless to say it quickly became overwhelming. But it's not just overwhelming for Michael. Cancer also impacts the lives of a cancer patient's friends and family. In her book There's No Place Like Hope: A Guide to Beating Cancer in Mind-sized Bites, cancer survivor Vickie Girard sums up the important role friends and family play in recovery and talks about how they often feel. She writes, "You walk through the darkness with us, not because you are ill and have to, but because you choose to. We were drafted, but you enlisted. We recognize and appreciate the difference more than words can ever say. YOU are our heroes, our support, and our reasons for fighting. To love a cancer patient is, in turn, to feel sad, frightened, concerned, angry, lost, and often helpless and to do all this, for the most part silently."
Home Page
A web site with general information and links to other sites about testicular cancer.
http://www.testicularcancer.co.uk

Extractions: Home Page Welcome to my web site about testicular cancer. This site has been built so information and awareness about testicular cancer is available to as many people as possible. On this site you will find information on how to do testicular self examination 'TSE' what to look for and what to do if you find a lump. you also find a link 's page which contains some web addresses and postal addresses for more support Groups and information centers. This web site has been created with my own experiences of testicular cancer and research from a number of sources, this site is for information and support only please seek medical advice immediately if you are worried. IF IN DOUBT CHECK IT OUT
Research And Clinical Trials - Office Of Rare Diseases
Information and links from this U.S. government source to other Internet sites which are oriented to clinical trials.
http://rarediseases.info.nih.gov/research-ct.html

Extractions: Links to the ClinicalTrials.gov database, the CRISP System (Computer Retrieval of Information on Scientific Projects), the Warren Grant Magnuson Clinical Center Hosptial, CancerNet and PDQ, and AIDS trials, as well as other databases helpful in accessing information on current or planned rare disease studies. If you enter the websites below, you will leave the Office of Rare Diseases website. Please return to our website to find more information on rare diseases, patient support groups and genetic counseling services. ClinicalTrials.gov - a service of the National Institutes of Health, developed by the National Library of Medicine, provides access to information from both Federally and privately funded clinical research studies. During the coming year, additional studies from other Federal agencies and the pharmaceutical industry will be added. Check this site often for updates.
Screening For Testicular Cancer
Information for doctors and health care professionals on screening for testicular cancer.
http://cancerweb.ncl.ac.uk/cancernet/304729.html

Extractions: This information is intended mainly for use by doctors and other health care professionals. If you have questions about this topic, you can ask your doctor, or call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). Note: A separate PDQ summary on Testicular Cancer Treatment is also available. There is insufficient evidence to establish that screening would result in a decrease in mortality from testicular cancer. Level of Evidence: 5 Opinions of respected authorities based on clinical experience, descriptive studies, or reports of expert committees It is projected that 7,200 new cases of testicular cancer will be diagnosed and 400 men will die of the disease in the United States in 2001.[1] Testicular cancer accounts for only 1% of all cancers in men. Despite a slow increase in observed incidence, there has been a dramatic decrease in the mortality as a result of new treatments. Unlike most other cancers, this disease is generally found in young men.[2] In white men, it is the most common cancer between 20 and 34 years of age, the second most common from 35 to 39 years of age, and the third most common from 15 to 19 years of age. This type of cancer is 4.5 times more common among white men than black men,[3] with intermediate incidence rates for Hispanics, American Indians, and Asians. High-risk groups exist. Males with cryptorchidism have 3 to 17 times the average risk. There is also an increased risk in males with gonadal dysgenesis and Klinefelter's syndrome.[4] Men with a family history of testicular cancer may be at a higher risk of this disease.[5] A history of testicular cancer is associated with a higher risk of a contralateral tumor.[6]
The Testicular Cancer Resource Center - Testicular Cancer Information For Everyo
The testicular cancer Resource Center A non-profit organization devoted to providingaccurate and timely information and support on all aspects of testicular
http://tcrc.acor.org/
Bmj.com Dearnaley Et Al. 322 (7302): 1583
British Medical Journal review on managing testicular cancer by DP Dearnaley, head of urology, RA Huddart, senior lecturer, A Horwich, professor at the Academic Unit of Clinical Oncology, Royal Marsden NHS Trust.
http://www.bmj.com/cgi/content/full/322/7302/1583

Extractions: Cancer:other BMJ 2001;322:1583-1588 ( 30 June ) Regular review DP Dearnaley head of urology RA Huddart senior lecturer A Horwich professor Academic Unit of Clinical Oncology, Royal Marsden NHS Trust, Sutton SM2 5PT Correspondence to: DP Dearnaley davidd@icr.ac.uk Germ cell tumours of the testis are the commonest malignancy in men aged 20-40 years. Considerable therapeutic improvements in management based on the cancer's responsiveness to chemotherapy that contains platinum mean that over 95% of these patients can now expect to be cured.
The Testicular Cancer Resource Center - Testicular Cancer Information For Everyo
The testicular cancer Resource Center A non-profit organization devoted to providing accurate and timely information and support on all aspects of testicular cancer and extragonadal germ cell tumors. testicular cancer The most common cancer in men between the ages of 15 and 35.
http://www.acor.org/diseases/TC
The Testicular Cancer Resource Center Dictionary
The testicular cancer Resource Center TC Dictionary Down to earth definitionsof confusing terms. Not as effective as Cisplatin for testicular cancer.
http://tcrc.acor.org/dictionary.html

Extractions: For Testicular Cancer and Related Conditions Adenomatoid Tumor - A very rare, benign tumor of the epididymis . On ultrasound it appears as a well defined, hyperechoic mass separate from the testicle. Adjuvant therapy - A treatment given in addition to the main treatment (for example, chemotherapy as well as surgery) to try to prevent a cancer from coming back, even though there is no indication that the cancer is still there. AFP - see Alpha-fetoprotein Alopecia - The loss of hair. It is a side-effect of most forms of chemotherapy or radiotherapy used to treat cancer. In the treatment of testicular cancer, the chemotherapy usually causes hairloss about 2 weeks after the start of chemotherapy. During radiation treatments, the patient may lose hair in the area being radiated. It is usually temporary. Alpha-fetoprotein - AFP is a protein found in the bloodstream of some men with nonseminomatous testicular cancer (It is NEVER present in seminoma patients). The level rises when the cancer is growing and falls when the cancer is shrinking or has been surgically removed, so a blood test can possibly measure the progress of the disease and success of treatment. Because of this behavior, it is referred to as a tumor marker . Elevated levels of AFP occur in 75 per cent of patients with teratocarcinoma embryonal cell carcinoma , and yolk sac carcinoma . (However, increased levels of AFP are also found in patients with liver diseases, such as cirrhosis, acute and chronic hepatitis and hepatic necrosis. ) The serum
E-Testicles.com; Information, Urogenital, Urology, Penis, Prostate, Testosterone
Testicular anatomy and functions. Spermatogenesis, hormonal regulation, testicular cancer, common disorders. Part of the ALtruis Biomedical Network.
http://www.e-testicles.com

Extractions: Testicles (testes) are the male gonads. Two of these stuctures are found in the scrotum where they produce the male gametes, the spermatozoa, and the male hormone, testosterone . The testes are suspended from the body by the spermatic cord which contains the ductus deferens or vas deferens, testicular blood and lymph vessels and nerves. The testicles are paired spheroid structures, (4 to 5 x 2.5 x 3 centimeters, 10.5-14 grams) housed in the scrotum with the dual function of producing sperm and hormones. The scrotum serves as a protective covering and serves to maintain the testicular temperature about 2 degrees below abdominal temperature. Each testicle is covered by a sac derived from the peritoneum acquired during its descent from the abdomen during fetal development . This sac has a an outer parietal layer and an inner visceral layer. Under this, each testis is surrounded by a thick capsule of collagenous connective tissue . The posterior surface of the sac is thickened to form the mediastinum from which septa extend into the gland to separate it into about 250 lobules. Each lobule is filled with with 1-4 seminiferous tubules, connective tissue, vascular supply, lymphatic vessels nerves and interstitial cells.

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