Geometry.Net - Health_Conditions: Vascular Dementia

Vascular Dementia And Memantine
Pharmacologic rationale for memantine in chronic cerebral hypoperfusion, especiallyvascular dementia. Mobius HJ. Merz and Co., Frankfurt, Germany.
http://www.memantine.info/memantine-3.htm

Extractions: Abstract Memantine is a moderate-affinity, voltage-dependent, uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors. In contrast to competitive NMDA antagonists, memantine is well tolerated in humans and is being developed for the treatment of dementia. The pathogenesis of vascular dementia (VaD) is largely unknown, and is likely multifactorial, but it involves the impairment of blood circulation as a common denominator. There is broad evidence for the efficacy of memantine in several animal models of ischemia. Memantine also acts on several secondary, potentially contributing factors in VaD such as neuronal depolarization, removal of magnesium block of NMDA receptors, chronic overstimulation of these receptors, and, possibly, mitochondrial dysfunction. Among others, it also has additional positive effects on long-term potentiation and cognition in standard animal models of impaired synaptic plasticity. Recently, clinical efficacy of memantine has been shown in an etiologically mixed population of severely demented patients, including those with VaD. Given the difficulties of diagnosing VaD in clinical practice, an optimal antidementive drug should be beneficial in both Alzheimer disease and VaD. Preclinical data presented in this paper indicate that such benefits can be achieved with
Memantine And Vascular Dementia
New approaches to clinical trials in vascular dementia memantine in smallvessel disease. Mobius HJ, Stoffler A. Merz Co. Frankfurt, Germany.
http://www.memantine.info/memantine-10.htm
A Z Psychiatry
vascular dementia. F01 vascular dementia. Vascular (formerly arteriosclerotic suggestingAlzheimer's disease. F01.1 vascular dementia Of Acute Onset.
http://www.azpsychiatry.info/icd/cognitive/vasculardementia.htm

Extractions: World Health Organization, Geneva, 1992 The diagnosis presupposes the presence of a dementia as described above. Impairment of cognitive function is commonly uneven, so that there may be memory loss, intellectual impairment, and focal neurological signs. Insight and judgement may be relatively well preserved. An abrupt onset or a stepwise deterioration, as well as the presence of focal neurological signs and symptoms, increases the probability of the diagnosis; in some cases, confirmation can be provided only by computerized axial tomography or, ultimately, neuropathological examination. Associated features are: hypertension, carotid bruit, emotional lability with transient depressive mood, weeping or explosive laughter, and transient episodes of clouded consciousness or delirium, often provoked by further infarction. Personality is believed to be relatively well preserved, but personality changes may be evident in a proportion of cases with apathy, disinhibition, or accentuation of previous traits such as egocentricity, paranoid attitudes, or irritability.
Vascular Dementia Dementia Care Caregiver Burden
Alzheimer Disease AlzheimerCentre. AlzheimerCentre Facing Alzheimer's disease. Alzheimer Disease Brain Disease Dementia Loss Memory . vascular dementia.
http://www.apiavia.com/Alzheimer_Disease/Vascular_Dementia.html
Vascular Dementia -- ECureMe.com
vascular dementia, more about vascular dementia, Multiinfarct Dementia.vascular dementia Dementia. more about vascular dementia, .. About
http://www.ecureme.com/emyhealth/data/Vascular_Dementia.asp

Extractions: March 31, 2003 Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health
Cognitive Functioning In Alzheimers Disease And Vascular Dementia: Further Evi
Cognitive Functioning in Alzheimers Disease and vascular dementiaFurther Evidence for Similar Patterns of Deficits. Kjell Fahlander
http://www.szp.swets.nl/szp/journals/jc246734.htm

Extractions: 2002, Vol.24, No.6, pp. 734-744 Cognitive Functioning in Alzheimers Disease and Vascular Dementia: Further Evidence for Similar Patterns of Deficits Kjell Fahlander , Åke Wahlin and Lars Bäckman Karolinska Institute, Stockholm Gerontology Research Center and NEUROTEC, Division of Geriatric Epidemiology, Stockholm, Sweden HM Queen Sophia College of Nursing, Stockholm, Sweden Uppsala University, Department of Psychology, Uppsala, Sweden The purpose of the present study was to examine possible differences in patterns of cognitive performance between population-based samples of Alzheimers disease (AD; n = 51) and vascular dementia (VaD; n = 14) patients between 75 and 96 years of age. The two demented groups were comparable in age, years of education, gender distribution, and severity of dementia. The selection of cognitive tasks (letter and category fluency, Block design, Clock reading and setting, and episodic face recognition) was thought to address some of the inconsistencies in previous research. The main finding was that AD and VaD patients were comparable on most tasks, although robust dementia-related deficiencies were found when comparing the results of the demented participants with those of the control participants. These findings suggest that AD and VaD may affect several basic cognitive functions in an equal manner.
Topic 12 Vascular Dementia
NINDS Search (search help). Contact us My privacy NINDS is part of the NationalInstitutes of Health Contact us . Content for this page. vascular dementia.
http://accessible.ninds.nih.gov/funding/neural_environment/stroke_prg/topic12.ht

Extractions: Funding - National Institute of Neurological Disorders and Stroke (NINDS) Skip menus Home About NINDS Disorders ... Find People The nation's leading supporter of biomedical research on disorders of the brain and nervous system. Select Topic Disorder Quick Links Alzheimer's Autism Cerebral Palsy Chronic Pain Epilepsy Headache Multiple Sclerosis Parkinson's Stroke Traumatic Brain Injury NINDS funding strategy Funding opportunities Grant mechanisms Research contracts ... Grants policy Contact staff - you are in this section Research training and career development Minorities and persons with disabilities Frequently asked questions E-mail notifications Funded grants/contracts (CRISP) ... Advisory council NINDS Search (search help) Contact us My privacy NINDS is part of the National Institutes of Health Contact us Get Web page suited for printing
Meyer_4255
vascular dementia Edited by John Stirling Meyer, MD Director Reviews vascular dementia. I recommend the book for neurologists and
http://www.futuraco.com/m_books/meyer_4255.htm
CyberSpace Search!
SEARCH THE WEB. Results 1 through 8 of 8 for vascular dementia.
http://www.cyberspace.com/cgi-bin/cs_search.cgi?Terms=vascular dementia
Characterization Of Risk Factors For Vascular Dementia
Characterization of risk factors for vascular dementia. The HonoluluAsiaAging Study. GW Ross, MD; H. Petrovitch, MD; LR White, MD
http://diabetes-mellitus.org/haas.htm

Extractions: G. W. Ross, MD; H. Petrovitch, MD; L. R. White, MD; K. H. Masaki, MD; C. Y. Li, MSc, MPH; J. D. Curb, MD; K. Yano, MD; B. L. Rodriguez, MD, PhD; D. J. Foley, MS; P. L. Blanchette, MD; R. Havlik, MD, MPH From the Department of Veterans Affairs (Drs. Ross and White), Honolulu; Department of Medicine (Drs. Ross, Petrovitch, White, Masaki, Curb, Rodriguez, and Blanchette), University of Hawaii John A. Burns School of Medicine, Honolulu; National Institute on Aging (D.J. Foley and Dr. Havlik), National Institutes of Health, Bethesda, MD; and Honolulu-Asia Aging Study (Drs. Petrovitch, White, and Masaki, C.Y. Li, and Drs. Curb, Yano, Rodriguez, and Blanchette), Kuakini Medical Center, Honolulu, HI. NEUROLOGY 1999;53:337 Background: Objective: To characterize patients with VaD by stroke subtype and to investigate risk factors for VaD in a cohort of Japanese American men, aged 71 to 93, living in Hawaii and participating in the HHP. Methods: Sixty-eight men with VaD were compared with 3,335 men without dementia or stroke (NSND). Men with VaD were also compared with 106 men with stroke who were not demented (SND). Candidate risk factors were measured prospectively.
Vitamins C And E May Protect Against Mental Decline
in the journal Neurology. vascular dementia is typically caused byobstructed blood circulation to the brain. This can lead to a
http://healthlink.mcw.edu/article/954383616.html

Extractions: Subscribe now >> Supplementing diets with antioxidant vitamins C and E may boost mental ability in later life and could protect against vascular and some other forms of dementia, according to a study published in the journal Neurology Vascular dementia is typically caused by obstructed blood circulation to the brain. This can lead to a series of minor cerebrovascular accidents that may cause impairment in thinking or memory functions. "We believe antioxidants like vitamins C and E may protect against vascular dementia by limiting the amount of brain damage that persists after a stroke," said study author Kamal Masaki, MD, of the University of Hawaii in Honolulu. "The supplements may also play a role in providing protection against brain cell and membrane injury involved in many aging-related diseases, thus resulting in significantly higher scores on mental performance tests in later life." The study investigated 3,385 Japanese-American men, aged 71 to 93, participating in the Honolulu Heart Program, a prospective study of heart disease and stroke initiated in 1965. The men were interviewed or surveyed in 1982 and 1988, and were assessed for dementia and mental abilities during exams in 1991 to 1993. Of the participants, 47 were diagnosed with Alzheimer's disease, 35 with vascular dementia, 50 with other or mixed types of dementia, 254 had low cognitive test scores without diagnosed dementia, and 2,999 men showed no cognitive difficulties.
VASCULAR-DEMENTIA
Search on This Term Main Index TopTerm Index Term Index Prev TermVALPROICACID Next Term vascular-DISEASES vascular-dementia. Broader Terms
http://www.alzheimers.org/chid/00001668.htm
Antiphospholipid Antibody Syndrome - New Treatments, February 5, 2003
New Treatments for Antiphospholipid Antibody Syndrome, February 5, 2003
http://redirect-west.inktomi.com/click?u=http://www.medical-library.org/journals

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