Extractions: What are the symptoms of Wilm's tumor? Wilm's tumor, also called nephroblastoma, is a malignant (cancerous) tumor originating in the cells of the kidney. It is the most common type of renal (kidney) cancer and accounts for about 6 percent of all childhood cancers. Approximately 400 children in the US are diagnosed with a Wilm's tumor each year. The disease can occur at any age between infancy and 15 years, but, in most cases, the tumor is detected by the age of 3. This cancer affects males and females equally. The tumor can be very large and it may spread (metastasize) to other body tissues. The most common site for Wilm's tumor to metastasize is the lungs. Lesions may also occur, however, in the liver, the other kidney, brain, and/or bones. In approximately 5 to 10 percent of children with Wilm's tumor, both kidneys are involved. Other tumors such as rhabdoid tumors of the kidney, clear cell sarcoma of the kidney, and mesoblastic nephroma occur in the kidney but are not Wilm's tumors and have different prognoses and treatment. Return to top What causes Wilm's tumor?
Wilms Tumor, Cincinnati Childrens Hospital Medical Center wagr syndrome WAGR stands for the four diseases present in this syndrome, includingWilms tumor, aniridia (absence of the iris, which is the colored part http://www.cincinnatichildrens.org/Health_Topics/Your_Childs_Health/Cancer/Condi
Extractions: Wilms tumor, also called nephroblastoma, is a malignant (cancerous) tumor that originates in the cells of the kidney. It is the most common type of kidney cancer in childhood, affecting males and females equally and accounting for about 6 percent of all pediatric cancers. Approximately 500 children in the United States are diagnosed with this tumor each year. Although the disease can occur at any age between infancy and 15 years, it is generally detected by age 3. The tumor can be very large and it may metastasize (spread) to other body tissues. The most common site of spread is the lungs, but lesions may also occur in the other kidney, the brain, and/or bones. In approximately 5 to 10 percent of children with Wilms tumor, both kidneys are involved. Treatment strategies depend on a number of factors, including the stage of the disease and the microscopic pathology of the tumor. However, surgical removal of the tumor is the cornerstone of therapy. Collaborative treatment strategies that involve pediatric surgeons, pediatric oncologists (cancer specialists), and radiation oncologists have resulted in cure rates that exceed 90 percent.
CancerGene WT1 Class, GATEKEEPER; TRANSLOC; TUMORSUPPRESSOR. Diseases, Kidney Neoplasms;Nephroblastoma; wagr syndrome. 607102, Link to 194072, wagr syndrome, (3). http://caroll.vjf.cnrs.fr/cancergene/CG199.html
Extractions: GDB SwissProt LocusLink Atlas of Genetics and Cytogenetics in Oncology and Haematology : Class GATEKEEPER; TRANSLOC; TUMOR-SUPPRESSOR Diseases Kidney Neoplasms; Nephroblastoma; WAGR Syndrome Note WT1 gene is fused to EWS ( CG:36 ) in t(11;22)(p13;q12) in desmoplastic small round cell tumor (DSRCT) ( UI:95166761 ). Lee et al. (1997, UI:98016415 ) concluded that the oncogenic fusion of EWS to WT1 in DSRCT results in the induction of PDGFA ( CG:403 ) , a potent fibroblast growth factor that contributes to the characteristic reactive fibrosis associated with this unique tumour. Identification of WTAP( CG:1423 ), a novel Wilms' tumour 1-associating protein by Little et al. (2000, UI:20458888 Comments Johnstone et al. (1996, UI:97098673 ) showed that WT1 and par-4 (prostate apoptosis response protein 4; CG:1034 ) interact specifically both in vitro and in vivo and that this interaction is mediated by the zinc fingers of WT1 and the leucine repeats of par-4. Functional analyses showed that par-4 inhibited transcription activated by WT1 and augmented WT1-mediated transcriptional repression. WT1 encodes a zinc finger transcription factor implicated in kidney differentiation and tumorigenesis. In reporter assays, WT1 represses transcription from GC- and TC-rich promoters, but its physiological targets remain uncertain. Lee et al. (1999
ACS :: What Are The Risk Factors For Wilms' Tumor? syndrome. In the wagr syndrome the same gene (the gene on chromosome11) may be partially or completely deleted in all body cells. In http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_factors_f
Results Of The Search Your submitted paragraph wagr syndrome A CONTIGUOUS GENE SYNDROME characterizedby the association of WILMS' TUMOUR (a childhood nephroblastoma) with Aniridia http://chaos.swmed.edu/etblast/user/user-1015659130/lforem.html
Extractions: Evidence for visual imagery deficits in persons with mental retardation. Aniridia-Wilms' tumour syndromea case report. General slowing of information-processing by persons with mental retardation. Development of a theory of mind in individuals with mental retardation. Mental retardation research in the Soviet Union. Research in mental retardation: toward an etiologic approach. Is outerdirectedness employed in a harmful or beneficial manner by students with and without mental retardation? Bybee J ... Zigler E Am J Ment Retard 1992 Mar;96(5):512-21.
WAGR Wheels Support Site WAGR WHEELS is a website for families affectedby wagr syndrome and related conditions.OurGoal is to link families to sources of information, to support, and http://www.angelfire.com/ga3/wagr/
Untitled otorenal syndrome Frasier syndrome renal dysplasia SimpsonGolabiBehmelsyndrome TownesBrocks syndrome wagr syndrome FURTHER INFORMATION http://www.nature.com/cgi-taf/DynaPage.taf?file=/nrg/journal/v3/n7/links/nrg842_
Health Library The results of your search for W are Waardenburg Syndrome. wagr syndrome.Waldenstrom's Macroglobulinemia. Waldmann Disease. Walker Warburg Syndrome. http://www.ochsner.org/library/healthguide/IllnessConditions/_SearchResults.asp?
Gene WT1ID78 affecting zinc fingers in exons 710. (wagr syndrome, genito-urinary(GU) anomalies, Denys-Drash-syndrome, Frasier syndrome; see below). http://www.infobiogen.fr/services/chromcancer/Genes/WT1ID78.html
Extractions: Home Genes Leukemias Solid Tumours ... Wilms' tumor Disease nephroblastoma of childhood Prognosis good with treatment according to NWTS or SIOP Cytogenetics 11p13 deletions/translocations can be seen in some cases Oncogenesis up to 15% of tumors show mainly biallelic inactivation of WT1 through deletion or mutatio Entity desmoplastic small round cell tumor (DSRCT) Prognosis poor Cytogenetics translocations, t(11;22)(p13;q12) Abnormal Protein With EWS : EWS-WT; in frame fusion of EWS exons 1-7 and WT1 exons 8-10 Entity Denys-Drash syndrome (DDS) Disease defined by: mesangial sclerosis with kidney failure (age 2 yrs), gonadal dysgenesis, risk of Wilms' tumors Prognosis kidney failure at age 0-5 years Hybrid/Mutated Gene dominant negative mutations, especially missense mutations within the zinc fingers (aa 394 Arg -> Trp) but very few nonsense mutations Oncogenesis high risk of Wilms' tumor development Entity Frasier syndrome Disease defined by: complete gonadal dysgenesis, focal glomerular sclerosis, gonadoblastoma; in karyotypic females the syndrome may be limited to focal glomerular sclerosis with regular gonadal development and function Prognosis kidney failure at age 10-30 years Hybrid/Mutated Gene heterozygous point mutations of alternative splice donor site in exon 9 with imbalance of WT1 isoform ratio Oncogenesis gonadoblatoma may occur within streak gonads External links Hugo Genes Cyto Gene Seq [Map View - NCBI] GeneCards CancerGene GDB Genatlas ... Genbank [ SRS ]
Extractions: On this page: Cherubs - A non-profit support group for the families and medical care providers of children and adults born with Congenital Diaphragmatic Hernia. Contact a Family - Information about this organization as well as the CaF directory of specific conditions and rare disorders. Also details about the Rare Disorders Alliance - UK. Fibrous Dysplasia Support Online - For those seeking support and information concerning the rare bone diseases: fibrous dysplasia, McCune Albright Syndrome and Cherubism. Human Growth Foundation - Information about growth-related disorders through education, research, and advocacy. Member driven organization. International Rare Disease Support Network - A community providing more than a 1000 different links to support groups for the people of all nations. Kindler Syndrome - An article and case study of this rare disease. Includes links. National Organization for Rare Disorders, Inc.
Extractions: About CDO Contact Us Join CDO Donate ... Volunteer Select a Page More about Chromosome Deletion Outreach Registered Chromosome Disorders CDO Family Stories Intro to Chromosome Abnormalities Ask the Doctor Library Resources Secure Application Form CDO Angels NICU Stories Guestbook T-Shirts FAQS Inspirational Chromosome Deletion Outreach, Inc.
Search By Disease 14 wagr syndrome. 15 WardRomano syndrome (WRS). Should you not find the diseasefor which you are searching, please send an email to EDDNAL eddnal@skypro.be. http://www.eddnal.com/directory/disease.php?letter=W
MUMS List Of Disorders - U - Z Disease (5) *. WSyndrome (1); wagr syndrome (Wilms Tumor-Aniridia-GonadoblastomaM.lR.) (8) *; Waardenburg Syndrome (6); Waardenburg http://www.netnet.net/mums/mum_u-z.htm
Extractions: indicates there is a support group which covers that diagnosis. UPJ Obstruction (4) Uhl Anomaly (Ventricular myocardium, aplasia of right) (1) Ulcerated Colitis (4)* Ulna Bone, absence, bilateral (arm bone) (3) * Ulna Bone, deficiency (arm bone) (4) * Undescended Testes (72) Undiagnosed (498) Unusual Facies Syndrome (5) Ureathra, Diverticulum (1) Ureter Reconstruction (5) Ureterostomy (5) Urethra Fistula (2) Urethra Valve Syndrome (6) Urethra, Diverticulum (1) Urogenital Sinus (2) Urorectal Septum Malformation Sequence (2) Urticaria Pigmentosa (9) Urticaria, Cold (1) Usher Syndrome Type II (1) * Uveitis (pars plantis -dots in vision) (3) * Uvulopalatopharyngoplasty (palate reconstruction) (2) VATER Syndrome or Vacterl Association (72) ** Vaccine Reaction to HIB Vaccine (6) * Vaccine Reaction to Measles Vaccine (9) * Vaccine Reaction to Pertussis (DPT) Vaccine (306) * Vaccine Reaction to Polio Vaccine (5) * Vaginal Cancer (2) * Vaginal Malformations (19) Vanishing Bile Duct Syndrome (1) Vanishing Twin Syndrome (5) Varicella-Zoster (Chickenpox), Fetal Effects (5)
GENATLAS GENE DATABASE RCN1, 11p13, reticulocalbin,Ca++ binding protein of the endoplasmic reticulum,involvedin protein processing,deleted in wagr syndrome, 602735, , -, y. http://bisance.citi2.fr/cgi-bin/mug?tex1=WT1
WAGR NETWORK LINK WELCOME TO THE REACHING OUT WAGR NETWORK LINK. THIS IS FOR ANY PERSONWISHING TO CONTACT OTHERS WITH KNOWLEDGE ABOUT wagr syndrome. http://groups.msn.com/WAGRNETWORKLINK
Extractions: Recommend This Group to a Friend WELCOME TO THE REACHING OUT WAGR NETWORK LINK. THIS IS FOR ANY PERSON WISHING TO CONTACT OTHERS WITH KNOWLEDGE ABOUT WAGR SYNDROME. THE DOCUMENTS HERE AT THIS LINK CONTAIN THE MEDICAL QUEST 2003 SURVERY CONDUCTED BY OUR NETWORK. THESE ARE MICROSOFT XL FILES AND CAN BE COPIED. WE ENCOURAGE IT. MICROSOFT VIEWER LINK: http://office.microsoft.com/downloads/2000/xlviewer.aspx OURWEBSITES WWW.WAGR.ORG http://members.aol.com/ReachingOutNet/ OUR E MAIL DISCUSSION GROUP IS http://groups.yahoo.com/group/WAGR FROM THERE YOU CAN FIND US! HOPE TO CONNECT WITH YOU SOON. SINCERELY, REACHING OUT, THE WAGR NETWORK New Messages View all Welcome
Wagr, Syndrome : Arborescences MeSH Translate this page wagr, syndrome. Menu général CISMeF. néphroblastome C04.700.635 pageCISMeF du motclef wagr, syndrome C04.700.635.950 page CISMeF du motclef http://www.chu-rouen.fr/navimesh/naviwagrsyndrome.html
Wagr-syndrome wagrsyndrome. From Date 15 Jan 2003 Time 111625 Remote Name 80.60.52.135.Comments. There was a question about wagr-syndrome in the 'old' discussionforum. http://www.chromosomehelpstation.com/_disc/00000003.htm
Article Textbase No 10 Translate this page wagr (syndrome). TextBase ID 10, Auteur(s)ADICAP SNOMED Table des matières http://www.anapath.necker.fr/pathbase/french/textbase/BankArticles/HTML/10.html
