Product Description
This digital document is an article from Health and Social Work, published by National Association of Social Workers on November 1, 1994. The length of the article is 5412 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: Thirteen persons diagnosed with amyotrophic lateral sclerosis were interviewed to determine the factors involved in making a decision whether to use mechanical ventilatory support. All study participants believed that they alone should make the decision regarding use of mechanical ventilation. The factors they considered to be of most importance were quality of life, severity of disability, availability of ventilation by means of a nasal mask, possible admission to a long-term care facility, ability to discontinue use of mechanical ventilation, desire to live, concern for their families' emotional health, and concern for care demands placed on their families. Suggestions are offered to facilitate the patient's decision-making process through provision of more information and improved dialogue between patient and professional.

Citation Details
Title: Amyotrophic lateral sclerosis patients' perspectives on use of mechanical ventilation.
Author: Jenny M. Young
Publication: Health and Social Work (Refereed)
Date: November 1, 1994
Publisher: National Association of Social Workers
Volume: v19Issue: n4Page: p253(8)

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This digital document is a journal article from Pratiques psychologiques, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
This article presents a review of the main research on the psychopathological disorders, the adaptive mechanisms an d the quality of life observed in patients with an amyotrophic lateral sclerosis. These publications show the good adaptation of the patients, who are not depressed, nor anxious an d who consider their quality of life as satisfactory. On the contrary, caregivers show more difficulties to adjust to the situation. These result underline the importance to follow the patients since the diagnosis, which remains an at risk period for the psychopathological disturbances, an d during the whole evolution of the disease. The taking care of the patients must include the caregivers an d adopt a multidisciplinary approach. ... Read more

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This digital document is an article from Clinical Psychiatry News, published by Thomson Gale on February 1, 2007. The length of the article is 819 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: ALS drug appears to ease resistant depression.(News)(amyotrophic lateral sclerosis)(Clinical report)
Author: Erik L. Goldman
Publication: Clinical Psychiatry News (Magazine/Journal)
Date: February 1, 2007
Publisher: Thomson Gale
Volume: 35Issue: 2Page: 1(2)

Article Type: Clinical report

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This digital document is an article from Journal of Neuroscience Nursing, published by American Association of Neuroscience Nurses on February 1, 1998. The length of the article is 2165 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the supplier: A nurse, totally physically paralysed, ventilator-dependent, yet able to communicate using a computer-operated voice machine, tells about her experience as a patient with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. She enrolled in a drug research study with the goal of sustaining hope and to be an active participant in her medical care.

Citation Details
Title: My journey with amyotrophic lateral sclerosis.
Author: Mary L. Nowotny
Publication: Journal of Neuroscience Nursing (Refereed)
Date: February 1, 1998
Publisher: American Association of Neuroscience Nurses
Volume: v30Issue: n1Page: p68(3)

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This digital document is an article from Journal of Medical Speech - Language Pathology, published by Thomson Gale on December 1, 2005. The length of the article is 3474 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Monitoring speaking rate by telephone for persons with amyotrophic lateral sclerosis.
Author: Laura J. Ball
Publication: Journal of Medical Speech - Language Pathology (Magazine/Journal)
Date: December 1, 2005
Publisher: Thomson Gale
Volume: 13Issue: 4Page: 233(8)

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Product Description
The article is excerpted fromGale Encyclopedia of Medicine.

Consultthe second edition of this authoritative, comprehensive, in-depthmedical guide for information on more than 1,700 medical topics inlanguage accessible to adult laypersons. Presented in a singlealphabetical sequence, articles range in length from one or twoparagraphs for minor topics, to several pages or more for major topics.Disease/disorder articles typically cover definition; description;causes and symptoms; diagnosis; treatments; prevention; and more.Test/treatment articles typically cover definition; purposes;precautions; preparation; risks; normal and abnormal results; and muchmore. This second edition includes more than 200 new entries, 300updated entries, approximately 650 color images and illustrations, anda comprehensive subject index. New features include biographical andhistorical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism thatproduces the condition; any risk factors that increase susceptibilityto the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used todiagnose the condition; how the test is done; who should be tested andwhen; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care ormanagement of the condition, such as drugs, surgeries, physicaltherapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Test/treatment articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the test/treatment
• Purposes -- why and when this test/treatment is prescribed
• Precautions -- when this test/treatment should not be prescribed
• Descriptions -- overview of the test/treatment including cost,length of time required, procedures followed, whether typically coveredby insurance
• Preparation -- pre-test treatment procedures, if any
• Aftercare -- post-test treatment procedures, if any
• Risks -- any complications/side effects commonly associated with the test/treatment
• Normal results -- for tests, describes the normal values; for treatments, describes the anticipated outcomes
• Abnormal results -- defines abnormal test values

Published/Released: December 2001

Product Description
The Amyotrophic Lateral Sclerosis Medical Guide is a publication which has been designed to better help readers understand Amyotrophic Lateral Sclerosis. This Qontro Medical Guide has been designed with the reader in mind, and is a useful information source for readers at all levels looking to learn more about Amyotrophic Lateral Sclerosis. The Amyotrophic Lateral Sclerosis Medical Guide is highly recommended for those interested in understanding and learning more about Amyotrophic Lateral Sclerosis. ... Read more

Product Description
This digital document is a journal article from Cognitive Brain Research, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
An attempt has been made to study the ability of patients with amyotrophic lateral sclerosis (ALS) to 'plan' a task. Electroencephalogram (EEG) data corresponding to 'planning of a movement task' is analyzed in comparison with a normal relaxed state. The study was conducted on 12 patients with ALS (6 males, 3 females, mean age 46.75 years) and on same number of controls (10 males, 2 females, mean age 48.75 years) to evaluate a difference in the ability to 'plan' a movement task between them. Patients with ALS were divided in two groups defined by unclear/clear speech. It has been observed that patients with ALS having unclear speech (Group I) showed considerable reduction (p<0.0001) in 'planning' a movement task, whereas patients with ALS having clear speech (Group II) showed no deficit in 'planning' a movement task (p=0.0577), both in comparison with age-matched controls. Apart from supporting the earlier reports of a possible extended neuronal degeneration across wide area of the frontal lobes, the findings reveal a possible reduction in planning, an executive function of the prefrontal cortex of brain, and also reveal that speech impairment may be associated with cognitive deficits in patients with ALS. ... Read more

Product Description
This digital document is an article from Westchester County Business Journal, published by Westfair Communications, Inc. on May 30, 2005. The length of the article is 472 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Grandpa inspires couple to strike back at ALS.(FLY ON THE WALL)(Amyotrophic Lateral Sclerosis)
Publication: Westchester County Business Journal (Magazine/Journal)
Date: May 30, 2005
Publisher: Westfair Communications, Inc.
Volume: 44Issue: 22Page: 37(1)

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Product Description
This digital document is an article from Southern Medical Journal, published by Thomson Gale on May 1, 2006. The length of the article is 574 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Normal chest radiograph in terminal respiratory failure due to amyotrophic lateral sclerosis.(Letter to the editor)
Author: Christine Won
Publication: Southern Medical Journal (Magazine/Journal)
Date: May 1, 2006
Publisher: Thomson Gale
Volume: 99Issue: 5Page: 551(2)

Article Type: Letter to the editor

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Product Description
This up-to-date electronic book on CD-ROM provides the best collection available anywhere of official Federal government information and documents on the subject of Amyotrophic Lateral Sclerosis (ALS), Lou Gehrig's Disease. This CD-ROM uses next-generation search technology that allows complete indexing and makes all files on the disc fully searchable. For patients, practical information is provided in clearly written patient education documents. For medical professionals, doctor reference tools and texts have detailed technical information and clinical background material.

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a progressive, fatal neurological disease affecting as many as 20,000 Americans with 5,000 new cases occurring in the United States each year. The disorder belongs to a class of disorders known as motor neuron diseases. ALS occurs when specific nerve cells in the brain and spinal cord that control voluntary movement gradually degenerate. The loss of these motor neurons causes the muscles under their control to weaken and waste away, leading to paralysis. ALS manifests itself in different ways, depending on which muscles weaken first. Symptoms may include tripping and falling, loss of motor control in hands and arms, difficulty speaking, swallowing and/or breathing, persistent fatigue, and twitching and cramping, sometimes quite severely.

This thoroughly researched collection presents vital information from many authoritative sources: Food and Drug Administration (FDA), Centers for Disease Control (CDC), National Institutes of Health (NIH), and the National Institute of Neurological Disorders and Stroke (NINDS). Contents include clinical and medical Information, with information on risk groups, signs, symptoms, testing, diagnosis, treatment, and clinical trials.

In addition to the comprehensive disease-specific coverage, as a bonus we have included an encyclopedic collection of general medical and health documents, with extensive material from the CDC, FDA, and NIH on hundreds of diseases. Since navigating the Internet to find additional non-governmental medical information can be confusing, we've also provided our exclusive "Guide to Leading Medical Websites" with updated links to 73 of the best sites for medical information! By using weblinks on the CD-ROM, you can quickly check for the latest clinical updates directly from the government.

This CD-ROM has over 29,000 pages reproduced using Adobe Acrobat PDF software and Reader software is included. Advanced search and indexing features are built into our reproduction, providing a complete full-text index. This enables the user to search all the files on the disk at one time for words or phrases using just one search command! The Acrobat cataloging technology adds enormous value and uncommon functionality to this impressive collection of government documents and material. There is no other reference that is as fast, convenient, comprehensive, and portable!

Our CD-ROMs are privately-compiled collections of official public domain U.S. government files and documents - they are not produced by the federal government. They are designed to provide a convenient user-friendly reference work, utilizing the benefits of the Acrobat format to uniformly present thousands of pages that can be rapidly reviewed or printed without untold hours of tedious searching and downloading. This book-on-a-disc makes a superb reference work and educational tool for patients and their families, physicians, and other medical professionals. (Information on this CD-ROM is not a substitute for professional medical advice; of course, readers are urged to consult with a professional health care provider for any suspected illness.) ... Read more

Customer Reviews (1)

ALS CD ROM
Information is excessive, not strongly related to the subject and highly disorganized. I had higher hopes for the content of the disc and am extremely dissatisfied. ... Read more

Product Description
This digital document is an article from Health and Social Work, published by National Association of Social Workers on February 1, 1998. The length of the article is 6249 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: Key words: adaptation; amyotrophic lateral sclerosis; coping; illness; positive life experience

Citation Details
Title: Against all odds: positive life experiences of people with advanced amyotrophic lateral sclerosis.
Author: Jenny M. Young
Publication: Health and Social Work (Refereed)
Date: February 1, 1998
Publisher: National Association of Social Workers
Volume: 23Issue: 1Page: 35(9)

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Product Description
This digital document is an article from Clinical Psychiatry News, published by Thomson Gale on November 1, 2006. The length of the article is 784 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Gulf War vets may face increased ALS risk.(veterans)(amyotrophic lateral sclerosis)
Author: Mary Ellen Schneider
Publication: Clinical Psychiatry News (Magazine/Journal)
Date: November 1, 2006
Publisher: Thomson Gale
Volume: 34Issue: 11Page: 44(1)

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Product Description

The present Competitive Intelligence Report about Amyotrophic Lateral Sclerosis (ALS) / Lou Gehrig’s disease provides a competitor evaluation about new treatments in the R&D pipeline of amyotrophic lateral sclerosis (ALS) / Lou Gehrig’s disease as of March 2009.

Amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's disease) is a rapidly progressing, motor neuron disease characterized by the gradual degeneration and death of motor neurons. When muscles in the diaphragm and chest wall fail, patients lose the ability to breathe without ventilatory support. Most people with ALS die from respiratory failure.Approximately 120, 000 new cases are diagnosed each year. No cure has yet been found for ALS. There is one FDA approved drug, riluzole, that modestly slows the progression of ALS.

Quite a number of approaches to treat ALS are being investigated in clinical trials:of the 20 different approaches, the majority (16) are small molecule based treatments, followed by biologics such as proteins, peptides and antibodies and more recently cell-based therapies have emerged for clinical testing. Among the targets being clinically tested are glutamate based therapies, antioxidants, cellular energy regulators, immunomodulators and neuroprotective/neurotrophic therapies. Biologic therapies study the neuroprotective effects of VEGF or are directed at the misfolded superoxide dismutase (SOD-1) among other approaches. Cellular therapies intent to induce regeneration of neuronal cells and tissues.

The report includes a compilation of current active projects in research and development of small molecules, antibodies, proteins, peptides, vaccines and other biologics including cells for treatment of amyotrophic lateral sclerosis (ALS). In addition, the report lists company-specific R&D pipelines of new treatments of ALS. Competitor projects are listed in a tabular format providing information on:

• Drug Codes,
• Target / Mechanism of Action,
• Class of Compound,
• Company,
• Product Category,
• Indication,
• R&D Stage and
• additional comments with a hyperlink leading to the source of information.